Dr. A.K.

Srivastava (Room I - 229)

BBL331 (Prerequisites BBL132, BBL133)

Microbial growth, substrate utilization and product formation kinetics; simple

structured models: batch, fed-batch, repeated fed-batch, CSTR, CSTR with
recycle, multistage CSTRs, and PFR: aeration and agitation, rheology of
fermentation fluids; mixing and scale up; air sterilization, media sterilization,
design of fermentation media, aseptic transfer.

References
1. Biochemical Engineering, By S. Aiba, A.E. Humphrey and N.F.
Millis, 2nd Edition, University of Tokyo Press, Japan
2. Biochemical Engineering Fundamentals By J.E. Bailey, D.F. Ollis
2nd Edition, McGraw Hill Book Company, New Delhi
. 3. Biochemical Engineering By J.M. Lee
Prentice Hall, Englewood Cliffs, New Jersey
4. Bioprocess Engineering, Basic Concepts By M.L. Shuler, F. Kargi
Prentice Hall, Englewood Cliffs, New Jersey
5. Bioprocess Engineering Systems, Equipment & Facilities
By B.K. Lydersen, N.A. D'Elia & K.L. Nelsen
John Wiley and Sons Inc. New York
6. Biological Reaction Engineering, I.I. Dunn, E. Heinzle, J. Ingham, J.E.
Prenosil, VCH Publishers, Weinheim.
7. Process Biotechnology Fundamentals, S.N. Mukhopadhyay, Viva Books
Pvt. Limited, New Delhi.
8. Fermentation and Enzyme Technology By D.I.C. Wang, C.L.
Cooney, A.L. Demain, P. Dunnill, A.E. Humphrey & M.D. Lilly
John Wiley and sons, New York
9. Principles of Fermentation Technology By P.F. Stanbury & A.
Whitaker Pergamon Press, New York
10. Biotechnology : A textbook of Industrial Microbiology By W
Crueger & Crueger, Sinauer Associates Inc, Sunderland, MA &
Science Tech, Inc. Madison, WI
11. Basic Biotechnology By J.Bulock & B. Kristiansen
Academic Press, New York (U.S.A.)
12. Concepts in Biotechnology By D. Balasubramanian, C.F.A. Bryce,
K Dharmalingam, J. Green, K Jayaraman. University Press, Hyderabad
13. Manual of Industrial Microbiology and Biotechnology, Arnold L.
Demain, Nadine A. Solomon, American Society for Microbiology,
Washington D.C.
14. Introduction to Industrial Sterilization, Richards
15. Principles of microbe and cell cultivation, S.J. Pirt

Minor I 20 Marks, Minor II -20 Marks, Tests (Surprise/Announced) 20 Major 40 marks