ATHMA

The maize P gene conditions red phlobaphene pigmentation to the pericarp

and cob. Starting from two unstable P alleles which carry insertions of the
transposable element Ac, we have derived 51 P null alleles; 47 of the 51 null
alleles have a 17-kb deletion which removes the 4.5-kb Ac element and 12.5
kb of P sequences flanking both sides of Ac. (1) The maize P gene is a
transcriptional regulator of genes encoding enzymes for flavonoid
biosynthesis in the pathway leading to the production of a red phlobaphene
pigment. (2) The Zea mays P gene has been postulated to regulate the
biosynthetic pathway of a flavonoid-derived pigment in certain floral tissues
[Styles, E. D. & Ceska, O. (1977) Can. J. Genet. Cytol. 19, 289-302]. We have
characterized two P transcripts that are alternatively spliced at their 3' ends.
(3) Legislation in some parts of the world now requires municipal solid waste
(MSW) to be processed prior to landfilling to reduce its biodegradability and
hence its polluting potential through leachate and fugitive emission of
greenhouse gases. (4) Recent gene expression QTL (eQTL) mapping studies
have provided considerable insight into the genetic basis for inter-individual
regulatory variation. (5) Physicians now recognize the importance and
usefulness of incorporating an assessment of health-related quality of life
(HRQL) in their clinical practice and clinical studies. (6) The maize P gene
encodes a Myb-homologous transcriptional regulator of flavonoid
pigmentation in floral organs, and different P gene alleles condition precise
tissue- and organ-specific pigmentation patterns. (7) The distributions of
residue hydrophobicity for individual domains as well as for the aggregates of
domains on a single chain have been found to exhibit well-defined second-
order hydrophobic moment profiles. (8) Exposure of plants to different biotic
and abiotic stress condition instigates significant change in the cellular redox
status; resulting in the elevation of reactive nitrogen species that play
signaling role in mediating defense responses. (9) We experienced severe
asthmatic crisis during general anesthesia in a 45-year-old man with IgG4-
related disease, COPD and athma undergoing removal of submandibular
gland. (10)

DAFTAR PUSTAKA
(1-10)

1. Athma P, Peterson T. Ac induces homologous recombination at the maize

P locus. Genetics. 1991 May;128(1):163-73. PubMed PMID: 1648001. Pubmed
Central PMCID: 1204445.
2. Chopra S, Athma P, Peterson T. Alleles of the maize P gene with distinct
tissue specificities encode Myb-homologous proteins with C-terminal
replacements. The Plant cell. 1996 Jul;8(7):1149-58. PubMed PMID: 8768374.
Pubmed Central PMCID: 161193.
3. Grotewold E, Athma P, Peterson T. Alternatively spliced products of the
maize P gene encode proteins with homology to the DNA-binding domain of
myb-like transcription factors. Proceedings of the National Academy of Sciences
of the United States of America. 1991 Jun 01;88(11):4587-91. PubMed PMID:
2052542. Pubmed Central PMCID: 51710.
4. Bhandari AR, Powrie W. Behavior of an MBT waste in monotonic triaxial
shear tests. Waste management. 2013 Apr;33(4):881-91. PubMed PMID:
23266323.
5. Pai AA, Cain CE, Mizrahi-Man O, De Leon S, Lewellen N, Veyrieras JB, et al.
The contribution of RNA decay quantitative trait loci to inter-individual variation
in steady-state gene expression levels. PLoS genetics. 2012;8(10):e1003000.
PubMed PMID: 23071454. Pubmed Central PMCID: 3469421.
6. Juniper EF. Effect of asthma on quality of life. Canadian respiratory
journal. 1998 Jul-Aug;5 Suppl A:77A-84A. PubMed PMID: 9753523.
7. Chopra S, Athma P, Li XG, Peterson T. A maize Myb homolog is encoded by
a multicopy gene complex. Molecular & general genetics : MGG. 1998
Nov;260(4):372-80. PubMed PMID: 9870702.
8. Zhou R, Royyuru A, Athma P, Suits F, Silverman BD. Magnitude and spatial
orientation of the hydrophobic moments of multi-domain proteins. International
journal of bioinformatics research and applications. 2006;2(2):161-76. PubMed
PMID: 18048160.
9. Imran QM, Falak N, Hussain A, Mun BG, Sharma A, Lee SU, et al. Nitric
Oxide Responsive Heavy Metal-Associated Gene AtHMAD1 Contributes to
Development and Disease Resistance in Arabidopsis thaliana. Frontiers in plant
science. 2016;7:1712. PubMed PMID: 27917181. Pubmed Central PMCID:
5116471.
10. Moriya M, Oda S, Nakane M, Kawamae K. [Severe asthmatic crisis during
general anesthesia in a patient with IgG4 related disease]. Masui The Japanese
journal of anesthesiology. 2014 Apr;63(4):418-22. PubMed PMID: 24783608.

Nama : Nadila Raudhani Permatasari

Stambuk : 110 2017 0108