RISK FACTORS

Predisposing Factors: Precipitating

Factors:

-Potential Genetic Endowment of HSPG1, HSPG2, HSPGX genes -Genetic

Mutation

-Advanced age: 85 years old -High intake

of red meat and fats

Normal cell mutates into an abnormal cell due to exposure/ intake of substances Genetic endowment of faulty genes resulting to development of
promoting carcinoigenesis cancerous cells

Formation originates in the following zones: Peripheral zone, Central zone, and
Transition Zone

Cancerous cells develop small clump formations noted as microscopic lesion ( Prostatic
Intraepithelial neoplasm) Dx Test:
Presence of active
levels of the Cancerous cells fails to undergo process of apoptosis causing continuous multiplication in Increase in
hormone an unregulated manner, and competes with normal cell utilization of body nutrients Prostatic Specific
testosterone Antigen (PSA):
Formation of Tumor in the prostate region
>100.00 ng/dl
(Adenocarcinoma)
Binds cancerous
cells’ androgen
Prostate cancer
CA cells skip citrate
production necessary for
Stimulates growth Metastasis
semen formation enables
and development of
energy conservation
Cancerous cells proliferates on local nearby structures
(urethra, bladder, seminal vesicles and nearby
structures).
 Symmetrically enlarged gland composed by
malignant cells

Narrows the Encroaches upon Growth of the so- Prostate capsule Dx Test:
lumen of the the bladder neck called median lobe influence
KUB with Prostate UTZ
segment of the reducing the of the prostate proliferation to
prostate ability to funnel extends into the expand outward Impression: Bilateral Renal
in response to proximal urethra Cyst; Grade 1 prostate
micturation enlargement by ultrasound
criteria; Ultrasonographically
Lower Urinary Tract Manifestations are normal urinary bladder.
Asymptomatic based on the patient’s
Assessment Dx Test reveals: Chest PA:
Unremarkable cardiopulmonary
findings. Blastic metastasis in
Progressive Systemic Metastasis
thoracic cage as described.
DX test reveals: Increased
levels of alkaline
phosphatase: 155.0 u/L

SGPT: 59.0 U/L Malignant cells Malignancy Metastasis to Metastasis to the

metastasized occurring the Dx test reveals: Bones Lungs
towards the hepatic regions of the
Large Intestinal
region colon Asymptomatic
ileus Blastic -DOB (+)
Altered liver Proliferation causes metastasis
function: decreased pressure on the noted -Ineffective gas
serum albumin surrounding normal exchange
Dx test reveals:
tissues of the -Pooling of secretions
abdomen Blastic bone resulting to Crackles
Dramatic decrease Generalized abdominal metastasis as upon auscultation (+)
in oncotic pressure pain noted on all described,
causes the quadrants with Pain scale hyperthropic -increased mucus
development of of 8/10. (Reflects through degenerative production (+) cough
Pitting Edema Nursing history during osteoarthropy with greenish sputum
(Grade 4) admission to the MSH ER) thoracolumbar spine