Professional Development for Health & Safety Experts

CHMM Question 08/24/2017 Toxicology & Risk

Your company is performing animal research on a new chemical that will eventually be
used in a pharmaceutical. Initial toxicology analysis shows that when administered to
mice, the lowest dose where a toxic effect is observed was 25 mg/kg. What is the
toxicological term for this dose?

A. LD50
B. NOAEL
C. LOAEL
D. IDLH

(Solution on next page)

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 Professional Development for Health & Safety Experts

Solution:

The Lowest Observed Adverse Effect Level (LOAEL) is defined as the lowest dose
where an adverse or toxic effect was observed.

The correct solution is C.

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www.BowenEHS.com
Copyright 2017 Bowen EHS A Division of Bowen Learning Network, Inc.