Mechanism of Action: Increases the refractory period via sodium- and potassium-
channel effects, and slows intra-cardiac conduction of the cardiac action
potential, via sodium-channel effects which leads to a delay in the rate at which
the heart's electrical system "recharges" after the heart contracts (repolarization)
it also acts on peripheral smooth muscle to decrease peripheral resistance.
Nursing Responsibility:
a.) Assess cardiovascular status before therapy and monitor blood pressure.
b.) Give drug with meals to decrease GI problems.
c.) Reserve use for life-threatening arrhythmias; serious toxicity, including
arrhythmias, pulmonary toxicity can occur.
d.) Arrange for regular periodic blood tests for liver enzymes, thyroid hormone
levels.
e.) Instruct patient that skin discoloration is reversible.
f.) Advice patient to wear sunglass for photophobia.
Nitroglycerine 50mg/10ml
Mechanism of action: Dilates blood vessels that supply the areas of the heart
where there is not enough blood flow and oxygen thus decreases cardiac
workload and myocardial oxygen consumption
Nursing consideration:
Nursing consideration:
Classification: Vasopressor
Nursing consideration:
a.) Monitor blood pressure, heart rate, pulse pressure and cardiac output.
b.) Monitor urine output throughout administration.
c.) If hypotension occurs, administration fate should be increased.
d.) Check for allergies and any adverse reaction.