Final Module Book-20160514

Dow University of Health Sciences
Integrated Modular Medical Curriculum
2016


Patron:
Prof. Masood Hameed Khan, Vice Chancellor,
Curriculum Committee:
Prof. Salahuddin Afsar, Chairman Curriculum Committee
Prof. Junaid Ashraf, Co-Chair Curriculum Committee
Prof. Khalid Mehmood, Co-Chair Curriculum Committee
Prof. Shams Nadeem Alam Member
Prof. Abdul Rauf Memon Member
Prof. Rukhsana Rubeen, Coordinator Medical Education Cell
Prof. Naheed Khan, Chief Module Coordinator,
Edited and compiled by:

Prof. Junaid Ashraf Co-Chair Curriculum Committee
Dr. Sabahat Zaidi Lecturer Anatomy, DUHS
Secretarial Assistance:
Nouman Khan Principal Office, DMC
Muhamamd Ahsan Lakhani Principal Office, DMC
Dow University of Health
Sciences is grateful to its faculty
for their contribution in the
preparation of the Integrated
Modular Curriculum.
The University is also thankful to

faculty and students for their
feedback and suggestions.
CURRICULUM COMMITTEE
CHAIRPERSON:
Prof. Salahuddin Afsar, Dean Faculty of Medicine, Pro Vice

MBBS, FCPS, FRCP, Chancellor, DUHS
CO-CHAIRPERSONS:
Prof. Junaid Ashraf, Professor of Neurosurgery, Principal

MBBS, FRCS,FRCS(SN) Dow Medical College.
Prof. Khalid Mahmood, Chairperson Department of

MBBS, FCPS, FRCP, Medicine,
MEMBERS:
Prof. Shams Nadeem Alam Professor of Surgery, DUHS

MBBS, FRCS,
Prof. Abdul Rauf Memon Professor of Medicine, DUHS

MBBS, FCPS,
Prof. Rukhsana Rubeen, Professor of Biochemistry, DUHS and

MBBS, M.Phil, Coordinator Medical Education Cell
Prof. Naheed Khan, Professor of Anatomy, DUHS,

MBBS, M.Phil Chief Module Coordinator
The following faculty members were involved
in the process of documentation of curriculum
at various stages.
12. Dr. Sabahat Zaidi

1. Dr. Arisha Sohail
13. Dr. Saima Rashid
2. Dr. Asim Rehmani
14. Dr. Sana Zia
3. Dr. Ateeba Ayesha Khan
15. Dr. Sara Khan
4. Dr. Fahad Khan
16. Dr. Shafaq
5. Dr. Faryal Tariq
17. Dr. Shahan Waheed
6. Dr. Ghazala Irfan
18. Dr. Sobia Shakeel
7. Dr. Kiran Afshan
19. Dr. Tanzeela Khan
8. Dr. Mehreen Ali
20. Dr. Tasneem Kausar
9. Dr. Momina Waqar
21. Dr. Zahaib Siddique
10. Dr. Muhammad Ali
11. Dr. Muhammad Arsalan Siddique
Integrated Modular Medical

Curriculum
2016
Volume 1
7
NEED FOR CURRICULAR REFORMS
Prof. Masood Hameed Khan

Vice Chancellor
Practice of medicine is a life-long process for a doctor and consequently learning is a

continuous process as well. These stages of learning in medicine are phasic which
initially are formal as demonstrated in the MBBS Medical Curriculum, Fellowship, M.
Phil and PhD while it continues in a non-formal manner during Continuous Medical
Education & Professional Development programs. A curriculum of a medical college or
university is guided by the content defined by regulatory / accreditation bodies i.e.
Pakistan Medical & Dental Council (PMDC) in our case, but it is a dynamic document
which needs to continuously evolve so that the graduates it produces are equipped with
the skills needed to provide quality health care to patients under their care, as this is
what are the needs of the society.
With the establishment of Dow University of Health Sciences in 2004 the MBBS
curriculum was reviewed and one glaring deficiency seen was the absence of a
document which showed all the elements that a curricular document should reflect like
the objective of the curriculum, the curricular perspective, syllabus, teaching
methodologies, time tables, assessment plans and faculty development plans. The
syllabus content that needed to be covered during the five year was given by PMDC as
well as the number of hours each subject needed to be taught. Guidance was sought
from PMDC and Higher Education Commission (HEC) in this regard and the
Universitys proposal of curricular review was endorsed by both bodies. This was the
start of the needs assessment process and a curricular committee comprising of Deans,
Chairpersons and Medical Educationists was formed to suggest methodologies to
cultivate a curricular. The philosophy of any good educational system is that it focuses
on making its participant a problem solver as well as a life-long self-organized learner
and these were the guiding principles for this process.
The first change was to switch from an annual examination to a semester system. Next
was introduction of more objective assessment tools like One Best Multiple Choice
Questions (MCQ), Objective Structured Clinical Examination (OSCE). The next stage
was integration of the disciplines initially in a horizontal and then in a vertical manner.
Integration is what is needed by the graduate to function competently in real-world
practice settings.
8
With the ongoing review processes and development after a journey of nearly five years
at present a modular format has been adopted with Interactive Lectures, Case Based
Learning in a small group formats as a teaching strategy. Students are encouraged to do
elective rotation outside the setting. Also non-formal experiential learning for student
is promoted by liaising with organizations which provide civic interaction. All this has
been structured taking into account the Best Evidence Based Medical Education
literature and our local culture and context.
No transformation is possible without the involvement of a dedicated faculty and staff,

which took on the task with unfathomed zeal and through their efforts the outcomes
which initially were thought to be a dream took on the shape of reality. Resistance to
change is a natural response but as Darwin said It is not the strongest of the species
that survives, nor the most intelligent that survives. It is the most adaptable to change
that survives. This is probably true for nations as well.
These curricular reforms were implemented simultaneously in all three constituent

medical colleges of Dow University of Health Sciences, namely Dow Medical College,
Sindh Medical College and Dow international Medical College. The change has also
been instituted in its affiliated institute Shaheed Mohtarma Benazir Bhutto Medical
College Lyari, Karachi whose students are examined by this University.
Hopefully with the passage of time this document will prove to be the first step in
continuing curricular reform in medical college of our country as it is an imperative
step which is needed to be taken to produce graduates who can accomplish what
society demands from them, quality patient care.
9
Curriculum Development: Initial Challenges
Prof. Salahuddian Afsar
Chairman Curriculum Committee
After the establishment of Dow University of Health Sciences, the primary focus
of the University was to improve academics. Given this, I was given the task of
developing a team to review the existing curriculum for M.B.B.S. It transpired
that there was no documented curriculum up until that point so our first step
was to critically analyze the existing system of teaching.
The teaching was subject based with no integration between different basic
science departments as well as none between the basic sciences and clinical
sciences departments. The focus was on memorizing the subject rather than on
critical thinking.
Upon the recommendation of this committee the University approached the

Pakistan Medical and Dental Council for permission to develop a new
curriculum on the lines of one which is being used all over the world.
On the initiative of Dow University of Health Sciences, in 2008, PMDC assigned

this task of developing an integrated modular curriculum to four universities of
Pakistan. Dow University of Health Sciences was one of them.
While developing this curriculum, the University changed the subject based
approach to vertically and horizontally integrated modular teaching. This
encompasses basic sciences and clinical sciences being taught in an integrated
fashion starting from first year.
Initially there were considerable reservations on the part of the faculty who were
used to the previous system and were skeptical initially, but with repeated
discussions they were eventually convinced, met the changes with enthusiasm
and took part in the development of the new curriculum.
From the first year we started Case Based Learning. After one week of teaching
the students were provided a clinical scenario in small groups so they could
relate what they studied to a more clinical approach. The University also
developed a skills lab so students learnt their hands-on skills before they
approached a patient in the wards.
10
Realizing the importance of research in the field of medicine, a research module
was incorporated in which students presented their research projects on a
research day under the supervision of faculty members.
The examination system was also modified. Instead of an annual system of

assessment there are more frequent modular assessments. The conventional
methods of clinical examination has also being replaced by OSCE (objective
structured clinical examination) which has eliminated subjectivity from the
assessments.
The quality enhancement cell of DUHS evaluates the system by collecting

feedback from faculty and students. These reforms have brought positive
changes in enhancing the academic standards of the institution.
Professor Salahuddin Afsar

Chairman,
Curriculum Committee
Dow University of Health Sciences,
Karachi.
11
CONTENTS
VOLUME-1
SECTION ONE
1. Basic organization of the integrated Modular Curriculum
2. Outline of the Curriculum Document
3. Definitions, Codes and Abbreviations
4. Five Year Curriculum Organization
5. Semester wise list of Modules
6. Skills Curriculum
SECTION TWO
a. Semester 1
b. Semester 2
c. Semester 3
d. Semester 4
VOLUME-2
e. Semetser-5
f. Semetser-6
g. Semetser-7
h. Semetser-8
i. Final year semester 9 and 10.
SECTION THREE
Consolidated Transcripts
Recommended Books
Review and Feedback
12
CONTENTS OF SEMESTER SUBSECTION
The contents of each semester subsection are in the following order in the respective
subsection :
i. Semester Title with Modules in the Semester,

Duration and credit Hours.
Module section
1. Title of the Module, with Module Code and
Semester.
2. Names of Members of module committee,
module coordinator and documenter.
3. Rationale of the module in the Curriculum
and Terminal Objectives.
4. Learning Objectives of the Module with modes
of information transfer and mode of
assessment of each objective.
5. Time Table with names of faculty and venue of
teaching.
6. Learning Objectives of Lectures and skill
curriculum.
7. Table of specifications.
8. Blueprint of assessment of the Module.
9. Credit Hours.
ii. Assessment Plan of the whole semester
iii. Viva Stations
iv. Semester Transcript
13
Section -1
14
BASIC ORGANIZATION OF
THE INTEGRATED MODULAR CURRICULUM
In 2008 Pakistan Medical and Dental Council assigned the task of developing an Integrated Modular
Curriculum to four medical universities of Pakistan. Dow University of Health Sciences was one of
these universities. The university started developing the curriculum in early 2009 and implemented it
with the new first year batch which started in November, 2009. The development of the curriculum
and its implementation occurred side by side. The experience gained by early implementation
provided an important feedback for correction and revision while the curriculum was being
developed. Since then the curriculum has been completely implemented and two batches of students
of the University have graduated after studying on this pattern.
The modular curriculum develop by Dow University of Health Sciences is integrated both in the
vertical and the horizontal directions. However in order to prepare the students for clinical teaching
with a sound background knowledge of the basic sciences, the curriculum has been divided in three
spirals.
The three spirals:
1. Spiral -1 Basic Sciences spiral

2. Spiral -2 Clinical Sciences spiral
3. Spiral -3 Integrated Supervised Practical Training
The Basic Sciences Spiral is spread over the first four semesters (the first two years) and clinical
sciences spiral is distributed over the next four semesters that is semester fifth to eight semester. In
the final year (9th and 10th semesters) students are given practical hands on training in the role similar
to that of a shadow house officer. They are encouraged to refer to the theoretical teaching of the first
four years for their practical training.
The whole curriculum is divided into modules, each module being related to a particular system for
example. Cardiovascular 1 module is in the Basic Sciences Spiral (Semester 2) and Cardiovascular 2
module is in the Clinical Sciences Spiral (Semester 5).
(BASIC SCIENCES) SPIRAL FIRST TO FOURTH SEMESTER
In Basic Sciences Spiral, anatomy, physiology, pharmacology, pathology, biochemistry and community
medicine are taught system wise (modules) an integrated fashion. Important clinical conditions
related to that particular system or also introduced at this stage so that the students can correlate
clinical presentation with the pathophysiology. Attempt is may to identify a particular theme from
that system for each weeks teaching. In this spiral, teaching is 80% that of basic sciences components
and 20% that of clinical sciences. Early introduction of pathology and clinical sciences provides the
students an early context of the purpose of the basic sciences teaching.
15
Case Based Learning:
During this spiral, a clinical case scenario is given to the students each week, which is made available
to them on the Curriculum Section website, prior to the commencement of teaching of that week. It
is expected that after completion of teaching of that week student will be able to analyze and discuss
the case scenario in small groups, in the presence of a faculty member whose role is primarily that of
a facilitator rather than a didactic teacher. Feedback is given to the students regarding their
discussion and assessment of the students in these sessions is forwarded to the Principal. This is part
of the formative assessment of the students.
(CLINICAL SCIENCES) SPIRAL FIFTH TO EIGHT SEMESTER
In this spiral, distributed over fifth to eighth semesters the students revisits the basic subjects of that
system while studying the clinical aspects. All the modules which have been taught in the basic
sciences spiral have the clinical sciences component in this second spiral. Eighty percent of the
teaching in this spiral is clinical based, medicine, surgery, pediatrics and gynecology & obstructers
etc. and 20% is basic sciences. While teaching in this spiral due importance and weightage is given to
more common diseases which afflict our society.
Scenario Based Learning (SBL)

Clinical case scenarios based on important diseases are discussed in small group format,
during the clinical postings. Scenarios are based on the module currently being taught.
Although cases are similar to those in the Case Based Learning, in the clinical spiral the
emphasis is on diagnosis, differential diagnosis and management plan.
Student Research Studies
In this spiral, in the fourth year (7th and 8th semesters) students are also given topic of
research studies which they conduct under the guidance of their assigned faculty
supervisors. Once the study is complete, it is presented in front of the faculty and students
for critique and analysis. Research studies are completed in the fourth year and are
presented in the final year.
16
THIRD SPIRAL (NINTH AND TENTH SEMESTER)
(INTEGRATED SUPERVISED PRACTICAL TRAINING)
By the end of the 8th semester the students have learnt the basic and clinical sciences subjects related
to each module. In their clinical postings from the 5th to 8th semester although they are exposed, by
observation, to practical management of the patients, they are not directly involved in the
management planning and implementation. The final year (9th and 10th Semesters) has been designed
to give practical training with the intent that by the time the students has graduated he/she has
already attained the competencies which are expected of a house officer. This practical training is
provided in the wards where the students are posted. Their responsibilities are that a shadow house
officers. They are encouraged to present and discuss cases on the ward rounds with the faculty and
amongst themselves with the supervision of the faculty members.
During the course of this education, certain subjects are taught as parallel themes and a taught in
different modules. These includes research methodology, ethics, communication skills, presentation
skills and conducting basic research studies and are encouraged to write research papers,
It is expected by the time the students have graduated and are ready for the house job, they have
already achieved the competencies required of them by the Pakistan Medical and Dental Council.
17
OUTLINE OF THE CURRICULUM DOCUMENT
This Curriculum Document has been prepared in accordance to the

guidelines provided by the Pakistan Medical and Dental Council and
Higher Education Commission for documentation of Integrated
Curriculum
It is divided in three sections.
The first section deals with the overall structure of the curriculum, its
five years organization into semesters and modules, list of modules
and the list of practical skills to be learnt during five years. The
assessment and promotion policies, and the codes of modules,
subjects and important abbreviations used in the document are also
given in the section.
The second section is divided into Semester subsections. Each

semester subsection begins with the names of modules in the
semester, duration of each module and its credit hour. Details of
individual modules is given separately.
While preparing the document of the module special consideration

has been given to follow the guidelines given by Pakistan Medical and
Dental Council for documenting each module.
Following are the subsection of each module document.

1. The title page of the module gives its code, the semester
and the year of the module.
2. This is followed by names of members of Module committee*,
the module coordinator and the person who documented the
module.
18
*The designations of the members of module committee are those which they
actually had at the time of preparation of the module. Some faculty members
have since then been promoted.
3. The Rationale of that module in the five year curriculum

4. The Terminal Objectives which a student is expected to have
achieved at the end of the module
5. The Learning Objectives of the Module are given in a tabular

form with the mode of transfer of knowledge,
( lectures, tutorials, practicals etc) and the means of
assessment(theory, ATP or viva)
LEARNING OBJECTIVES:
Objectives of module are listed in following grid along with contents and teaching methodology
Self Study
CBL / SBL
One Best,
Skills Lab
Tutorials
Lectures
Practical
Library
Demo:
Digital
EMQS
ATP
viva
Topic /
Objectives SUBJECT
Content
Modes of information Transfer Assessment
HEM 1 Ane-1:
Recognize the Embryological
structure of development
hAnematopoietic
ANATOMY of blood
1.75 * *
tissues and
mechanism of elements.
hAnematopoesis Hematogenesis
6. Time Table the modes of transfer of information is organized in

the form of a weekly timetable. As a sample one of the time tables
which has been run most recently has been given. In the time table,
for generalization, names of faculty members and the venue of the
teaching have been eliminated.
19
FOUNDATION MODULE TIME TABLE
(This time table was for year 2015. Holidays represent actual holidays in that year)
First Week: (Cell)
ORIENTATION DAY
DA 11:00 -
8:30- 9:30 9:30-10:30 11:45-12:30 1.30-2.30
Y 11:45
INTRODUCTIO INTRODUCTION
INTRODUCTION N TO TO ORIENTATION TO COLLEGE
WEL COME BY TO PHYSIOLOGY BIOCHEMISTRY
DA ENVIRONMENT
THE PRINCIPAL ANATOMY & FACULTY & FACULTY
Y1 Name Of Faculty & FACULTY Name Of Name Of
VISIT TO DEPARTMENTS
VENUE Name Of Faculty Faculty Faculty
VENUE VENUE VENUE
7. Learning Objectives of the Lectures along with their codes is

given in the next section. These also include the learning objectives of
the skills curriculum.
LEARNING OBJECTIVE OF LECTURES
AT THE END OF THE LECTURE THE STUDENT SHOULD BE ABLE TO
EMBRYOLOGY
EMBRYOLOGICAL DEVELOPMENT OF BLOOD ELEMENTS.

HEM 1 Ane1 Ane1
HEMATOGENESIS
Define hematopoiesis.
Ideentify and Descibe the sites and source of heamopoiesis before and after birth
Differentiate stem / pluripotentd cells, progenitor and precursor (blasts) cells
Explain the development of various types of blood cells
8. The Table of Specification is prepared by calculating the

contribution of each discipline in actual hours in each module
(designated as Total 1)
The same is then calculated as percentage and the percentage
distribution is given as Total 2.
The percentage distribution is used to prepare the examination
material.
20
TABLE OF SPECIFICATIONS
KEY:
Total teaching hours of a discipline in module / total teaching hours of module100
Total 1= total of discipline based teaching
Total 2= total of integrated teaching (cbl)
WEEK 1st 2nd 3rd 4th 5th 6th Round of

TOTAL ***
% for
GEN ANAT. - - - - - - - PAPER II
-
EMBR 1.75 - - - - - 1.75 1.22

1
HISTO 1.50 - - - 4 1.75 7.25 5.08

6
PHYSIO 7 6.25 5 1.75 2 1.75 23.75 16.66

17
BIOCHEM 9.25 2.75 - - 1 1.75 14.75 10.35 11
PHARM 1 2.50 6 1.75 1 1 13.25 9.29
10
PATHO 4.50 4 7.25 5.25 2 9.75 32.75 22.98

23
MICRO 3.25 7 2.75 2.75 7 - 22.75 15.96

16
COM.MED 2.50 1.50 1 1 - 1.50 7.50 5.26

6
BEH.SCI 1 - 1.50 1 - 1 4.50 3.15

3
RES.METH 1.50 1.75 - - - - 3.25 2.28

2
SKILLS 1.50 - 1.75 1.75 1.50 - 6.50 4.56

-
CLINICAL 2 1.50 - 1 - - 4.50 3.15
FACULTY 5
TOTAL 1 36.7 29 27 18 20 20.25 142.5 99.94 100
5
TOTAL 2 1.75 1.75 1.75 1.50 1.75 8.50 - -
Proportionate weightage to be given to each subject in written and oral examinations.
9. Blueprint of Assessment of the module is given in the next

section. This includes both the composition of the module paper and
the semester paper.
21
BLUEPRINT OF ASSESMENT
FOUNDATION MODULE
(SEMESTER 1)
SUMMATIVE ASSESMENT
THEORY
ASSESMENT TOOLS MARKS WEIGHTAGE

One best Questions 55
SEMESTER
ATP 25
EXAM
PAPER-I 80%
One best Questions
20
based on CBL
Total 100
10. The last section contains the Credit Hours of the module.
After all the modules of the semester have been detailed, the
Semester Assessment Plan, semester credit hours, the composition of
structured viva stations and finally a sample of the Semester
transcript which is currently being used by Dow University of Health
Sciences , is given.\
The Final year (Semester IX and X) subsection provides these details

on the subject format.
The third section contains subsections which are common to all

modules. These include
1. The Consolidated Transcript of the five years assessment is

given both in semester wise and module wise format as
a. The Consolidated Semester transcript.
b. The Consolidated Modular transcript.
2. The list of some of the recommended books. However the

students have been advised to widen their search of knowledge by
accessing other sources of information as well.
3. The last part of the final section has the outline of feedback and
evaluation process employed by the University for continuous review
and revision of the Curriculum.
22
DEFINITIONS, CODES AND ABBREVIATIONS
DEFINITIONS
Definitions of the following terms used in the Curriculum Document have been
taken from HEC Guidelines.
CREDIT HOURS:
1. A credit hour means teaching a theory course of 50 minutes each week throughout the semester .
(1 semester=16 weeks, 1 lecture of 50 minutes / week x 16 = 1 credit hour).
2. One credit hour in laboratory or practical work / project would require lab contact of two hours per
week throughout the semester.
GRADE POINT AVERAGE:
Computation of semester grade point average (GPA) and Cumulative grade point average (C.GPA)
Semester Grade point Average (GPA) and Cumulative Point Average (C.GPAs) will be calculated
using the following relationships:
GPA = Sum over courses in Semester (Course Credit Hours X Grade Point Earned)
Total Semester Credit Hours
C.GPA = Sum over all taken Courses in all Semester (Course Credit Hours X Grade Point Earned)
Total Credit Hours Taken in all Semester
15 MIN OF INFORMATION TRANSFER/ LEARNING=0.25 HRS

30 MIN OF INFORMATION TRANSFER/ LEARNING =0.5 HRS
45 MIN OF INFORMATION TRANSFER/ LEARNING =0.75 HRS
60 MIN OF INFORMATION TRANSFER/ LEARNING =1 HR)
23
CODES
Each of the curriculum spirals, modules, subjects and lectures have been
assigned a distinct code consisting of alphabets and numbers.
Spiral Code:
The curriculum is organized in three cycles
First Spiral (basic sciences based teaching) Code 1

Second Spiral (clinical sciences based teaching) Code 2
Third spiral Final year (hands on supervised training) Code 3
For instance
Foundation Module is in first Spiral FND 1
Respiratory System Module in First Spiral RSP 1
Respiratory System Module in Second Spiral RSP 2
24
SUBJECT CODE
Each subject is designated by a code consistent three of alphabets.
Subjects code is as follows:
S. No. Code Subject

1. Ang Gross Anatomy
2. Anh Histology
3. Ane Embryology
4. Phy Physiology
5. Bio Biochemistry
6. Pha Pharmacology
7. Pth Pathology
8. Mic Microbiology
9. Com Community Medicine
10. For Forensic Medicine
11. Beh Behavioral Sciences
12. Res Research Methodology
13. Cbl Case based learning
14. Med Medicine
15. Sur Surgery
16. Ped Pediatrics.
17. Obg Obstetrics & Gynecology
18. Psy Psychiatry
25
Module code:
Each Module is designated by a code consistent three of capital alphabets
followed by the number of that module.
For example: the Respiratory System Module in the Basic Sciences Cycle is
coded as:
RSP-1
And the same module in the Clinical Sciences Cycle is coded as
RSP-2
MODULE CODE:
.No. Code Subject

1. FND1- Foundation
2. HEM1- Blood Module
3. LCM1- Locomotion
4. RSP1- Respiratory System
5. CVS1- Cardiovascular System
6. NEU1- Nervous System
7. HNN1- Head & Neck & Special Senses
8. END1- Endocrinology
9. HEM2- Hematology
10. RSP2- Respiratory System
11. CVS2- Cardiovascular System
12. HEM2- Hematology
13. GIL 2- GIT and Liver (including Nutritional Disorders)
14. EXC2- Renal and Excretory System
15. END2- Endocrinology
16. REP2- Reproductive System
17. ORT2 - Orthopedics, Rheumatology and Trauma care
18. NEU2- Neurosciences and Psychiatry
19. GEN- Genetics
20. OPH- Ophthalmology
21. ENT- Ear Nose
22. DPS- Dermatology & Plastic Surgery.
23. PMR- Physical Medicine & Rehabilitation.
24. ENV- Environmental & disorders
26
Lectures And Examination Material Code:
Each lecture is coded with its module code, subject code and its serial
number in that module for example, the six physiology lecture in the
Respiratory System Module in the basic cycle coded as
RSP1 Phy1, RSP1 Phy2, RSP1 Phy3,
The examination material related to these lectures, prepared in the

Q-Bank and stored in the Examination Department, are also coded in
the same way. This facilitates preparation of examination paper in
accordance with the curriculum.
27
ABBREVIATIONS
KEY:
MCQ: Multiple Choice Questions

ATP: Alternate to Practical
EMQ: Extended Matching Question
BCQ: Best choice Question (Single best question)
CBL: Case Based Learning
SBL: Scenario Based Learning
OSPE: Objective structured Practical Evaluation
OSCE: Objective structured Clinical Evaluation
HEC: Higher Education Commission
PMDC: Pakistan Medical & Dental Council
QEC: Quality Enhancement Cell
28
LIST OF MODULES AND CREDIT HOURS
CREDIT
S.NO. SEMESTERS MODULES
HOURS
1. Sem-1 Foundation Module 9
2. Blood Module-1 9
3. Sem-2 Locomotor Module-1 9
4. Respiratory System-1 4.5
5. Cardiovascular System-1 4.5
6. Sem-3 Neurosciences-1 9
7. Head & Neck & Special Senses 4.5
8. Endocrinology-1 4.5
9. Sem-4 GIT and Liver-1 9
10. Renal and Excretory System-1 4.5
11. Reproductive System -1 4.5
12. Sem-5 Infectious diseases 4.5
13. Hematology-2 4.5
14. Respiratory System -2 4.5
15. Cardiovascular System-2 4.5
16. Sem-6 GIT and Liver- 2 9
17. Renal & Excretory System-2 4.5
18. Endocrinology-2 4.5
19. Sem-7 ENT 4.5
20. Orthopedics-2 / Trauma, 6
21. Reproductive System-2 7.5
22. Sem-8 Ophthalmology 4.5
23. Rheumatology & Rehabilitation 4.5
Genetics & Dermatology
24. Neurosciences and Psychiatry-2 9
25. Medicine 13.5
Sem-9
Pediatrics 4.5
26. Surgery 13.5
Sem-10 Gynecology & Obstetrics 4.5
TOTAL CREDIT HOURS 180
29
FIVE YEAR CURRICULAR ORGANIZATION
SPIRAL SEM MODULES

FND1- Foundation HEM1- Blood Module
Cell, Genetics & Cell Death (Basics of Anatomy, Immunity, Inflammation, Tissue repair,
I Physiology, Biochemistry, Microbiology, Antimicrobials & Neoplasia
Gen. Pathology, and Gen. Pharmacology, Community 8 Week
Medicine & Behavioral Sciences) 8 Weeks
First II LCM1- Locomotion RSP1- Respiratory CVS1- Cardiovascular

Spiral Bones, Joints, Nerves & Muscles, 8 Week System 4 Weeks System 4 Weeks
NEU1-Nervous System HNN1- Head & END1- Endocrinology
III 8 weeks Neck & Special 4 weeks
Senses 4 Weeks
GIL 1-GIT and Liver EXC1- Renal and REP1- Reproductive
IV 8 week Excretory System System 4 week
4 Week
V IDD 1- Infectious HEM2- Hematology RSP2- Respiratory CVS2- Cardiovascular
diseases 4 weeks 4 weeks System 4 weeks System 4 weeks
GIL 2-GIT and Liver (including Nutritional EXC2- Renal & END2- Endocrinology
VI Disorders) 8 weeks Excretory System 4 weeks
4 weeks
Second th
Half of the class will cover Ophthalmology in first 3 weeks of 7 Semester and the other half will cover ENT modules
th
Spiral during this period. In the first 3 weeks of 8 semester the module will rives
VII OPH / ENT ORT2 Orthopedics /
Trauma, 6 weeks
REP2- Reproductive System
3 weeks 8 Weeks
OPH / PMR- DPS- GEN- NEU2- Neurosciences and Psychiatry
ENT Rheumatology & Dermatology Genetics 8 Weeks
VIII 3 weeks Rehabilitation Plastic Surger 1 week
/ Burns
2 Weeks
2 weeks
th
Half of the class will cover Medicine & Allied and the other half will cover Surgery & Allied modules in the 9
th
semester. The two half will exchange in the 10 semester.
Clinical Rotation 8:30 to 1:00 (with Ambulatory, Emergency, Clinical Rotation 8:30 to 1:00
Intensive care) (Inpatient, Ambulatory, Emergency, Intensive care and
In Medicine, Pediatrics, Cardiology and Neurology units Operation Theatres)
1:30 to 3:00 pm In Surgery, Gynae& Obstetrics, Orthopedics and
Third IX & Lecture on problem based approach, twice a Neurosurgery. 1:30 to 3:00 pm
Spiral X week Lecture on problem based
Ward tutorial twice a week approach, twice a week
Student research Ward tutorial twice a week
presentation once a week Student research presentation once a week
PARALLEL THEMES:
The following themes are not part of any individual module but shall run concurrently :
Communication Skills, Clinical Skills, Writing and Presentation Skills, Article Writing, Ethics
30
Curriculum of Practical skills
The following practical skills are taught to the students by Simulation in the
Undergraduate Skills Lab of the Professional Development Centre.
First year
Semester I
1.1 FOUNDATION MODULE
1. First aid skills part 1
2. First aid skills part 2
1.2 BLOOD MODULE
3. Intramuscular injection & Venipuncture
4. Intravenous Cannulation
Semester II
2.1 LOCOMOTOR MODULE

5. Vital Signs
6. Basic Life Support
2.2 RESPIRATORY SYSTEM
7. Introduction to respiratory system
2.3 CARDIOVASCULAR SYSTEM
8. Introduction to cardiovascular system examination
31
Second Year
Semester III
3.1 NERVOUS SYSTEM
9. Introduction to central nervous system examination
3.2 HEAD & NECK & SPECIAL SENSES
10. Cranial nerves examination
3.3 ENDOCRINOLOGY
11. Examination of prostate
Semester IV
4.1 GIT & LIVER
12. Introduction to abdominal examination
13. Nasogastric Intubation
4.2 RENAL & EXCRETORY SYSTEM
14. Male urethral catheterization
15. Female Urtral catheterization
4.3 REPRODUCTIVE SYSTEMS
16. Examination of breast
32
Third Year
Semester V
5.1 INFECTIOUS DISEASES
17. History taking skills
5.2 HEAMATOLOGY
18. Introduction to Advanced Cardiac Life Support
5.3 RESPIRATORY SYSTEM
19. Auscultation of lungs
5.4 CARDIOVASCULAR SYSTEM
20. Auscultation of heart
Semester VI
6.1 GIT & LIVER (INCLUDING NUTRITIONAL DISORDERS)
21. abdominal examination
22. history taking
6.2 RENAL & EXCRETORY SYSTEM
23. Male & female urethral catheterization
6.3 ENDOCRINOLOGY
24. Arterial puncture
33
Fourth Year
Semester VII
7.1 ENT
25. Otoscopy
7.2 EYE
26. Ophtalmoscopy
7.3 DERMATOLOGY, PLASTIC SURGERY /BURNS
27. introduction to basic Surgical Skills
a. instrument handling
b. knotting
c. Basic suturing
7.4 REPRODUCTIVE SYSTEM
28. Examination of breast
7.5 GENETICS & ENVIRONMENTAL DISORDERS
Semester VIII
8.1 NEUROSCIENCES & PSYCHIATRY
29. Lumbar Puncture
8.2 ORTHOPEDICS, RHEUMATOLOGY & TRAUMA CARE (BONES &

JOINTS)
30. Revision of First Aid Skills
34
Final Year
Semester IX and X
9.1 31. Emergency Life Saving Skills Medicine
9.2 32. Emergency Life Saving Skills Pediatrics
9.3 33. Emergency Life Saving Skills Gynecology and Obstetrics
9.4 34. Emergency Life Saving Skills Surgery
35
ASSESSMENT AND PROMOTION POLICIES
In its assessment and promotion policies University has followed the guidelines
of Pakistan Medical and Dental Council. Although assessment is conducting
both at the modular and semester levels, the weightage of internal
assessment, the distribution of marks, clearance of both theory and viva
components and clearance of all the examinations of a year being the pre
condition for promotion to next year are essential ingredients of these policies.
ASSESSMENT POLICIES
The assessment is both formative and summative.
FORMATIVE ASSESSMENT
In the small group discussions conducted each week on the Case Based
Learning and Scenario Based Learning sessions, the facilitator not only
encourages the students to discuss the cases amongst themselves but also
assesses them and provides a feedback for improvement to them at the e nd of
the session. A copy of this assessment is forwarded to the respective Principal.
STUDENT CBL / SBL EVALUATION

DATE ----------------------
SEMESTER--------------------------- MODULE---------------------------------------
CBL/SBL TOPIC------------------------------------------------------------------------------------------------------------
INTEGRAT RESPONDED
INITIATE
E TO OTHER
ATTEND PUNCTUA THE TOTAL
SERI STUDE ROL PREVIOUS GP.
ED LITY DISCUSSI MARKS
AL NT L KNOWLED MEMBERS
ON
NO: NAME NO: GE POSITIVELY
2 2 10
2
2 2
1.
2.
3.
4.
36
5.
FACILITATOR---------------------------------------------------------------------------------------------------------------
NAME OF FACILATATOR -------------------------- SIGNATURE-----------------------------------
In the Clinical postings in the third, fourth and final year the students are
regularly assessed during and at the end of the posting and are provided
feedback for improvement. Copies of the posting records are forwarded to the
Principal of the college.
SAMPLE PAGE OF THE GRADE BOOK

Name of Students Year Roll No.
Posted from ____________ to ___________ for _____________ days

(dated) (date) (date)
*GRADE
ATTENDANCE (in word)
____(Maximum)_____
(Attended)
Ward
Ward Test Attendance Participation Total
Roll No. Grade
(50) (20) (100)
(30)
CLINICAL TEACHING UNIT:
__________________________________________________________________
(Sd.) Students Date (Sd.) Teacher

__________________________________________________________________________
*For grading see Rules and Regulation at the end.
SUMMATIVE ASSESSMENT
The summative assessment consists of the module and semester examinations.
37
Module examinations There is a module examination at the end of each
module. The content of the whole teaching of the module are tested in this
examination. It consists of a single paper of objective type questions. The
distribution of the questions is based on the Table of Specifications of the
module. There can be 75 to 100 questions depending on the duration of the
module. Sixty percent of the questions are of single best type. The remaining
questions are divided on extended matching questions and Case based learning
type integrated questions. The examination is centralized, conducted by the
examination department and students of all constituent and affiliated colleges
have to take this examination. Twenty percent of the weightage of the
Semester theory paper of that module is based on the module examination.
The Assessment plan of each Module is given at the end of each module
document.
Semester examination At the end of the semester there is a semester

examination which consists of one theory paper based on the contents of each
module and a structured viva which consists of 8 to 10 stations of five minutes
each.
Written Paper There is one written paper for each module of the
semester. For example, if there are three modules in one semester,
papers I, II and III will correspond to the written components of these
modules.
Each written paper has 75 to 100 objective type questions depending on

the duration of teaching in the module. Sixty percent of these questions
are of short scenario BCQ type and the remaining of long scenario case
based type. These questions are maximally of integrated format.
Structured Viva The distribution of stations is based on the weightage

of individual disciplines. For example there are more stations of Anatomy
in the Locomotor component of viva. Likewise there are more stations of
Physiology in the Hematology component in the basic sciences spiral.
Although VIVA stations are discipline based, maximum effort is made to
adhere to the principles of integration while preparing the questions for
structured viva.
38
DISCIPLINE WISE DISTRIBUTION OF VIVA STATIONS IN THE
SEMESTER EXAMINATION
Spiral I Spiral II
Subject Semester Semester Total
1 to 4 5 to 8
Anatomy 12 12
Physiology 10 10
Biochemistry 7 7
Pharmacology 1 8 9
Pathology 6 7 13
Medicine* 6 6
Surgery** 6 6
Ophthalmology 4 4
ENT 4 4
*Medicine includes Internal Medicine,

Neurology, Cardiology and
Total 36 35 71
Dermatology.
**Surgery includes General Surgery, Neurosurgery and Orthopedics.
The Assessment plan of each semester along with marking and weightage
of papers and their credit hours is given at the end of each semester
document.
39
Final year
The fifth year is the third spiral, the year of supervised integrated practical
training.
Ophthalmology and ENT have already been examined in the fourth year and
although the teaching and examination in these two disciplines is modular they
have been given full weightage as that of a subject in accordance with the
PMDC requirement .
The final year examination is subject based. Medicine, Surgery, Pediatrics and
Gynecology & Obstetrics are the four subjects examined in the final year. There
is both a written and a practical examination of each subject with equal
weightage given to theory and practical examination.
The assessment plan of the final year subjects are given at the end of each
subject in the Final year section.
40
PROMOTION POLICIES
The University follows the promotion policy in accordance with the guidelines
of Pakistan of Medical and Dental council
There is a Semester examination at the and or each Semester and a

retake examination of both the odd and even Semesters of the year, after
the even Semester examination.
Students can be promoted from odd (1,3,5,7, & 9) to even semester

(2,4,6,8, & 10 respectively ) even if they have not clear the subjects of the
odd semester but they have to clear all papers of each year, and their
component, before being promoted to next year.
Students who fail to clear any paper, either theory or viva, have to retake
only the component they have failed in.
As per PMDC policy, clearance of all the papers of first year in four
attempts is essential for continuation of medical studies.
41
Integrated Modular Medical

Curriculum
2016
Volume 2
42
SPIRAL -1
Basic Sciences
43
SEMESTER -1
Foundation Module 8 Weeks 9 CreditHours
Hematology-1 Module 8 Weeks 9 Credit Hours
44
FOUNDATION MODULE
(FND 1)
Semester 1
First Year MBBS
45
5 YEAR CURRICULAR ORGANIZATION
Spiral Sem. Modules

First LCM1- Locomotion RSP1- Respiratory CVS1- Cardiovascular
II
Spiral Bones, Joints, Nerves & Muscles, 8 Week System 4 wks System 4Week
III NEU1- Nervous System HNN1- Head & END1- Endocrinology

8 weeks Neck & Special 4 weeks
GIL 1-GIT and Liver Senses 4 weeks
EXC1- Renal and REP1- Reproductive
4 Week
diseases 4 week 4 week System 4week System 4 week
VI Disorders) 8weeks Excretory System4 4 weeks
wks
Second th
Spiral th
during this period. In the first 3 weeks of 8 semester the module will rives
VII OPH / ENT ORT2 Orthopedics / REP2- Reproductive System
Trauma, 6 week
3 week 8 Weeks
VIII ENT Rheumatology Dermatology Genetics 8 Weeks
3 wk & Rehabilitation Plastic Surger 1 wk
/ Burns 2 wk
2 Weeks
th
th
1:30 to 3:00 pm In Surgery, Gynae & Obstetrics, Orthopedics and
PARALLEL THEMES:
46
MODULE COMMITTEE
Dr Naheed Khan (focal person) Professor of Anatomy, DUHS

Dr. Khalida Parveeen, Professor of Anatomy, DUHS
Prof. Zeba Haque Professor of Biochemistry, DUHS
Prof. Mahmood Hasan Professor of Pathology, DUHS
Prof. Saud Hasan Professor of Pharmacology, DUHS
Prof. Nighat Nisar Professor of Community Medicine, DUHS
Dr. Yasmeen Taj Professor of Pathology, DUHS
Dr. Muhammad Rafique Professor of Anatomy, DUHS
Dr. Kelash Nankani Professor of Physiology, DUHS
Dr. Rukhsana Rubeen Associate Professor of Biochemistry, DUHS
Documented by:
DR. NAHEED KHAN
DR. SABAHAT ZAIDI
Coordinated by:
DR. SABAHAT ZAIDI
Reviewed by:
Module committee
Curriculum committee
47
RATIONALE:
A Student stepping into a medical school requires orientation, and

introduction to medical sciences with respect to health & disease. The
student also needs certain guidelines to achieve goals to become a
successful but ethical doctor in future.
Foundation module provides integration of core concepts that underlie the

foundation of basic sciences and their use in clinical medicine. This will
eventually lead to develop critical thinking for integration and application
of basic knowledge for clinical application
TERMINAL OBJECTIVE:
By the end of the Foundation module the student shall be able :
Define levels of organization of human body

Identify homeostatic mechanism and its importance in body functions
Describe the anatomy, biochemistry & physiology of cell
Enlist different modes of transportation across the cell membrane
Interpret the biochemistry of carbohydrates, proteins and fats
Define & illustrate stepwise embryological mechanism of cell
Discuss histology of epithelium, glands & muscles
Recognize morphologic alterations in cell injury & cell death.
Define behavioral sicences and its roll in medicial sciences
Elaborate community medicine and its application for a medical
doctor
48
Objectives of module are listed in following grid along with contents and
teaching methodology
Lectures
Demo:
Tutorials
Practical
CBL / SBL
Self Study
Library
Digital
spotting
Practical /
One Best, EMQS
Skills Lab
viva
Objectives
Faculty Topic / Content
Modes of information Transfer Assesment
Conceptualize ANATOMY Fnd1Ang1 Levels of organization of 1 -

the integrated human body
* *
assembly of
structures and
functions in
human body by
relating with the
arrangement of
different LEVELS
OF
PHYSIOLOGY Fnd1Phy1 Homeostatic mechanism of 1
ORGANIZATION
major functional system
* * *
Recognize the Fnd1Phy2 Extra cellular fluid and 1.5

role of
internal environment
* * *
physiochemical
aspects for the BIOCHEMISTRY Fnd1 Bio 1 Extra-cellular Matrix 1
maintenance of * *
homeostasis.
INTEGRATED Fnd1 Cbl 1 Fluid and electrolyte 3 -
LEARNING imbalance
* *
Identify the BIOCHEMISTRY Fnd1 Bio 2 Organization of living 1.5 -

different types, system: The macromolecules
* *
occurrence and
role of
macromolecules
for the healthy
living of human
Use light HISTOLOGY Fnd1Anh1 Introduction to microscopy 1.5 - -
beings.
microscope to
*
identify the
various tissues
stained by H/E
Relate HISTOLOGY Fnd1Anh 2 Cell Introduction 1
staining.
organization and
* * *
structure of
different
components of a
Fnd1Anh 3 Cell Organelles 1.5
cell
arrangement of
and
(Endoplasmic Reticulum, Golgi
* * *
cells in organ Apparatus, Ribosomes, Centrioles,
system manner Mitochondrion, Lysosomes,
in a living human
Peroxisomes
body. Fnd1Anh 4 Nucleus 1
* * *
49
Lectures
Demo:
Tutorials
Practical
CBL / SBL
Self Study
Library
Digital
spotting
Practical /
One Best, EMQS
Skills Lab
viva
Objectives
Fnd1Anh 5 Inclusions 1 -
* *
(Lipid, Glycogen, Pigments:Melanin,
Lipofuscin,Lutein ) & Secretory
Granules
Fnd1Anh 6 Cytoskeleton 1 -
(Microtubules, Filaments: Thick,
* *
Thin /Microfilaments, Intermediate)
Fnd1Phy3 Physiological role of Cell 1

PHYSIOLOGY: Organelle
* * *
50
Lectures
Demo:
Tutorials
Practical
CBL/SBL
Self Study
Library
Digital
spotting
Practical /
BCQs,SEQs,
Lab
EMQS
Skills
viva
Objectives Faculty Topic / Content
Correlate the 1
composition and HISTOLOGY Fnd1Anh7 CELL MEMBRANE :
* A
* *
basic structure of cell Composition & Structure
BIOCHEMIST Fnd1 Bio 3 Cell membrane 1.5 -
membrane with its
RY
* *
functional
importance and
adaptation
Interpret the PHYSIOLOGY Fnd1Phy4 Transport Of 1.5
physiological basis of Substances Across Cell Membrane
* * *
different types of : Passive Transport
transport
Fnd1Phy5 Transport Of 1
mechanisms through
Substances Across Cell Membrane
* * *
cell membrane
: Active Transport (Special
Reference To Sodium Pump
Recognize the exact GROSS Fnd1Ag2 Terminologies: 1.5
location of a ANATOMY Anatomical positions, Terms of
* * *
dissected/prosected positions, Anatomical planes
part /organ of
human body with
respect to various
TERMS of
POSITIONS,
DIRECTION,
Interpret theand GROSS Fnd1Ag3 Terms of movement 1.7
BODY PLANES.
movements of ANATOMY 5
* * *
different parts of
human body
PATHOLOGY Fnd1 Pth Introduction of 1
pathology , Outline of cellular
* *
response to stress and injury
the knowledge of ,Types of adaptations of Cellular
various TERMS of
Growth and Differentiation
MOVEMENT.
Fnd1 Pth Adaptations of Cellular 1

Discuss the
pathological aspects Growth and Differentiation
* * *
of cell and different Fnd1 Pth Cell injury and cell death 1
mechanisms * * *
associated with Fnd1 Pth Morphologic Alterations 1.75
morphological in Cell Injury
* * *
specturm of injury at
Fnd1 Pth Mechanisms of Cell 1 -
simple and electron
Injury
* *
micrscopic levels.
Fnd1 Pth Apoptosis 0.75 -
* *
Fnd1 Pth Pathological calcification 1 1.5
* * *
Fnd1 Pth Intracellular 1
Accumulations
* * *
Fnd1 Pth Introduction of 1.5 - -

pathology laboratory
*
51
Lectures
Demo:
Tutorials
Practical
/CBL/SBL
Self Study
Library
Digital
spotting
Practical /
BCQs, SEQs
Skills Lab
EMQS
viva
Objectives
Modes of information Transfer

Assesment
Differentiate HISTOLOGY: Fnd1Anh8 Mitosis and Cell 1
between normal cycle
* a * *
and abnormal
EMBRYOLOGY Fnd1Ae1 Meiosis + 1
cell division and
Comparison With Mitosis
* * *
their
consequences
Fnd1Anh9 Epithelium:1 1 1.5 * * *
Types, Location, Functions
Fnd1Anh10 Epithelium:2 1
Types, Location, Functions
* * *
Fnd1Anh11 Cell Surface 1
Recognize the Modification
* * *
organization of (Microvilli,
Fnd1Anh12Cilia, Flagella
Cell Junctions 1
cells in the HISTOLOGY * *
epithelium and
Fnd1Anh13 Exocrine glands 1
other basic * * *
tissues of body Fnd1Anh14 Connective 1 1.5
tissue1: components
* * *
Fnd1Anh15 Connective 1
tissue2: classification
* *
description of each type
Fnd1 Mic 1 Basic bacteriology 1

* * *
Differentiate a
Fnd1 Mic 2 Structure of 1
human cell from
bacterial cell
* * *
a bacterial cell
for the Fnd1 Mic 3 Bacterial Genetics 1 -
* *
recognition of
Fnd1 Mic 4 An account of 1.5 - -
disease caused
Microbiology lab: use of
*
by bacteria MICROBIOLOGY microscope &different
staining methods
Fnd1 Bio 4 Water: Structure 1.5 -

Application of
BIOCHEMISTRY and Dissociation
* *
basic principles
of chemistry in Fnd1 Bio 4 Buffers and pH 1.5 -
body
* *
homeostasis
52
Lectures
Demo:
Tutorials
Practical
CBL/SBL
Self Study
Digital Library
spotting
Practical /
BCQs, SEQs
Skills Lab
EMQS
viva
Objectives Topic / Content
Faculty
Fnd1 Bio5 Carbohydrates: Structure, 1 -

Use the knowledge Classification and Functions
* *
of CARBOHYDRATE
BIOCHEMISTRY Fnd1 Bio6 Carbohydrates: Isomerism 0.75
chemistry for
and Monosaccharide Derivatives
* * *
health
Classify protein on Fnd1 Bio7 Amino Acids: Structure, 1 -

the basis of Classification and Functions
* *
BIOCHEMISTRY
structure, function
and chemical
Fnd1 Bio8 Proteins: Structure, 1
reactions and
Classification and Functions
* * *
recognize their
importance in
Justify thediet and Fnd1 Bio9 Fatty acids: Structure, 1 -
balanced
importance of BIOCHEMISTRY Classification and Functions
* *
health
LIPIDS for balanced
Fnd1 Bio10 Lipids: Structure, 1
diet and health.
Classification and Functions
* * *
Fnd1Ag4 Introduction to 1.75 1.5
Integumentary system
* * *
Appreciate the
function of Support Fnd1Ag5 Bones ,Division and 1.75 1.5
and Protection by Function of Skeletal System,
* * *
using the general Classification of Bones, Gross
GROSS
knowledge of SKIN, Structure of Adult Long Bone, Parts of
ANATOMY
FASCIA and BONES Young Long Bone
and their
Fnd1Ag6 Bone development 1.75
component tissues
(ossification) Blood supply of long
* * *
bone Cartilage Bone marking
Fnd1Ag7 General concepts of muscles 1.75

GROSS
* * *
Associate the ANATOMY
Movement and
Fnd1Anh16 Muscular tissue 1 1.5
Posture of human
HISTOLOGY
* * *
body with the
structure of
Fnd1Ag8 General concepts of joints 1.75
MUSCLES and
GROSS * * *
JOINTS.
ANATOMY
Explain the process Fnd1 Bio11 Energy flow within the 1 -

of energy flow cell 1
* *
BIOCHEMISTRY
within the cell.
Fnd1 Bio12 Energy Flow Within The 1 -
Cell 2
* *
53
Lectures
Demo:
Tutorials
Practical
/CBL/SBL
Self Study
Library
Digital
spotting
Practical /
BCQs, SEQs
Skills Lab
EMQS
viva

Explain the Fnd1Anh17 Blood vascular 1.75 1.5
Physiological system
* * *
functions of (CAPILLARIES,ARTERIES,VEINS
Transportation
HISTOLOGY , ANASTOMOSIS)
and Exchange by
applying
knowledge of
structure of
BLOOD VESSELS.
Integrate the Fnd1Ag9 Introduction to 1
function of GROSS Lymphoid system
* * *
Defense with ANATOMY
the structure of
LYMPH NODES Fnd1Anh18 Lymphoid system 1
AND
I: LYMPH NODE, THYMUS
* * *
LYMPHATICS.
HISTOLOGY:
Fnd1Anh19 Lymphoid system 1
II : TONSIL AND SPLEEN
* * *
Correlate the Fnd1Ag10 Nervous System 1.7
functions of Division CNS, PNS Neurons: 5
* * *
Control and Types Classification , Nerve
Regulation with
GROSS (With Its Covering ) & Myelin
the knowledge
ANATOMY
of arrangement
1.7
and Distribution
Fnd1Ag11 Typical Spinal 5
* * *
of NERVOUS
SYSTEM. Nerve
Fnd1 Bio13 Nucleic Acids 1 1 -

* *
Fnd1 Bio14 Nucleic Acids 2 1 -
* *
Fnd1 Bio15 Replication and 1 -
Repair
* *
Apply the basic
concepts of
Chemistry of Fnd1 Bio16 Transcription 1 -
Nucleic acids
* *
and their types Fnd1 Bio17 Post- 1 -
for
Transcriptional Modification
* *
understanding BIOCHEMISTRY
the mechanism
Fnd1 Bio18 Translation And 1 -
of transfer of
Post-Translational
* *
genetic
characters and Modification
for protein
synthesis. Fnd1 Bio19 Regulation of 1 -
Gene Expression
* *
Fnd1 Bio20 Gene defects 1.5 -

* *
54
Fnd1 Pth Human Genetic 1
PATHOLOGY
Architecture
* * *
Lectures
Demo:
Tutorials
Practical
CBL/SBL
Self Study
Library
Digital
SEQs EMQS
spotting
Practical /
BCQs,
Lab
Skills
viva
Objectives
Conceptualize Fnd1 Ae15 Fetal Membranes 1

the interchange Amnion(including disorders of
* * *
of substances amniotic fluid) Chorion
between
EMBRYOLOGY +umbilical cord, Yolk Sac
maternal and
Fnd1 Ae16 Placenta 1
fetal blood by * * *
applying the
Fnd1 Ae17 Multiple 1
knowledge
structure
of
and pregnancies
* * *
Relate the Fnd1 Ae18 Teratogenesis 1
functions
various
of
placentabirth and
* * *
defects
fetal with
genetic factors
membranes
and
environmental
teratogens EMBRYOLOGY
Fnd1 Ae19 Prenatal diagnosis 1 -
Recognize the * *
importance of
procedures for
assessing fetal
status for the
well being of
newborn infant
Fnd1Phy7 Cell Signaling
Effectof PHYSIOLOGY Mechanisms:1st & 2nd
* * *
endogenous
(physiological) Messengers
Fnd1 Pha9 Receptor 1
and
classification, property, Type
* *
exogenous(drug PHARMACOLOGY
) moloecules
& Mechanism of drug actions
on functioning Fnd1 Pha10 Signaling 1
of cells Mechanisms G-protein
* *
coupled receptors
Fnd1 Pha1 Introduction to 1.75
Pharmacology
* *
Fnd1 Pha2 Routes of 1.5
administration of drugs
* * *
Corelate the Fnd1 Pha3 Dosage of drugs, 1 1.5
principles of
Calculation and clinical
* *
general
pharmacology application, Therapeutic
for the PHARMACOLOGY index, Preclinical & clinical
appropriate
trials, bioassays
Fnd1 Pha4 Factors Modifying 1.75
therapy of
disorders / The Drug Response
* *
diseases
Fnd1 Pha5 Pharmacokinetics 1
Absorption Of Drug
* *
Fnd1 Pha6 Biotransformation 1
of drugs.Phase-1& Phase-11
* *
55
Fnd1 Pha7 Excretion of drugs 1
& factors affecting the
* *
excretion of drugs
Fnd1 Pha8 Adverse drug 1
reactions/Drug-Drug
* *
interactions
Fnd1 Ae8 First Week Of 1
Development After
* * *
Fertilization
Fnd1 Ae9 2nd Week Of 1.75
Development
* * *
Identify the
various stages of
development of Fnd1 Ae10 3rd week of 1.75
human embryo
development,
* * *
to understand
the mechanism Gastrulation: formation of
of primitive
Fnd1 Ae11streak and of
3rd week 1.75
developmental EMBRYOLOGY notochord
development neurulation and
* * *
disorders and development of somites
anomalies
Fnd1 Ae12 Fourth To Eighth 1.75
Weeks Organogenetic Period
* * *
Phases Of Embryonic
Development
Fnd1 Ae13 Fourth to Eighth 1
Weeks Organogenetic Period
* * *
Highlights of The Fourth To
Eighth Weeks
Fnd1 Ae14 Fetal Period (9th 1
Week till birth)
* * *
56
BCQs, SEQs
Practical /
Self Study
/CBL/SBL
spotting
Lectures
Tutorials
Practical
Library
Demo:
EMQS
Skills Lab
Digital
viva
Fnd1 Com1 introduction to 1.5 -

public health & community
* *
Recognize the medicine
importance of
Fnd1 Com2 origin and 1 -
Community determinants of disease
* *
medicine for COMMUNITY
the MEDICINE
Fnd1 Com3 health systems 1 -
development of * *
Fnd1 Com4 healthy city 1 -
public health * *
Fnd1 Com5 health system 1 -
research
* *
Fnd1Beh1 Introduction to 1 -
Behavioral Science web 1
* *
1
Fnd1Beh2 Culture, Cultural
Recognize the Influences, Belief
1 *1 - *
1
importance of
BEHAVIORAL
behavioral
SCIENCES Fnd1Beh3 Delivery
sciences * - *
culturally relevant care
Fnd1Beh4 Value & -

Attitudinal Transformation
* *
Fnd1Res 1 Topic Selection 1.5 - -

*
Fnd1Res 2 Objective Writing 1.5 - -
Recognize the *
importance of
research RESEARCH
Fnd1Res 3 Questionnaire 1.5 - -
methodology
METHODOLO
Making
*
GY/
for conducting communicati
research work on skill Fnd1Res 4 Literature Search 1.5
* - -
in later year
Fnd1Res 5 Study Designs 1.5 - -

*
57
FOUNDATION MODULE
Time Table
First Week: (Cell)
DAY 8:30- 9:30

ORIENTATION DAY
9:30-10:30 11:00 - 11:45 11:45-12:30 1.30-2.30
INTRODUCTION INTRODUCTION TO INTRODUCTION TO

ORIENTATION TO COLLEGE
WEL COME BY TO PHYSIOLOGY BIOCHEMISTRY
ENVIRONMENT
DAY 1 THE PRINCIPAL ANATOMY & FACULTY & FACULTY
Name Of Faculty & FACULTY Name Of Faculty Name Of Faculty
Name Of Faculty VENUE VENUE VISIT TO DEPARTMENTS
VENUE
VENUE
Day 8:30- 9:30 9:30-10:30 11:00 -12:00 12:00 -12:45 1:30-3:00
ANATOMY PHYSIOLOGY: BIOCHEMISTRY

Levels of PHYSIOLOGY
Homeostatic Organization of living
organization of Extra cellular fluid and internal
DAY 2 mechanism of major system: The
human body environment
functional system macromolecules
Name Of Faculty Name Of Faculty
Name Of Faculty VENUE
Name Of Faculty
VENUE VENUE VENUE
HISTOLOGY PHYSIOLOGY:
HISTOLOGY : HISTOLOGY
CELL MEMBRANE : Transport Of Substances Across Cell
CELL Introduction INTRODUCTION TO
DAY 3 Composition & Membrane Passive Transport
Name Of Faculty MICROSCOPY
Structure Name Of Faculty
VENUE
VENUE Name Of Faculty
VENUE
PHYSIOLOGY: ANATOMY 5 GROUPS
Transport Of HISTOLOGY :
HISTOLOGY : Terminologies: Anatomical
Substances Cell Organelles (Endoplasmic Reticulum, Golgi
Nucleus Apparatus, Ribosomes, Centrioles, positions, Terms of
DAY 4 Across Cell positions, Anatomical planes
Name Of Faculty Mitochondrion, Lysosomes, Peroxisomes
Membrane Active
Transport Name Of Faculty
VENUE
(Special VENUE
Reference To
Sodium Pump PATHOLOGY:
Name Of Faculty Introduction of pathology
VENUE
PHYSIOLOGY , Outline of cellular
10.30-12.00
Physiological role response to stress and ANATOMY 5 groups
DAY 5 of Cell Organelle injury Types of TERMS OF MOVEMENT
Name Of Faculty adaptations of Cellular Name Of Faculty
Growth and VENUE
VENUE
Differentiation
Name Of Faculty
VENUE
ANATOMY
Terminologies: 10.30-12.00
DAY 6 Anatomical positions, Terms of positions, HISTOLOGY REVISION
Anatomical planes, Terms of movement CELL MEMBRANE : Composition & Structure
Revision by NUCLEUS Name Of Faculty
VENUE
58
Time Table: Second Week:
(Theme: Intercellular connections)
Days 8:30- 9:30 11:00 -12:00 12:00 -12:45 1.30-3.00
9:30-10:30
DAY 1
DAY 2
HOLIDAY
HISTOLOGY: EMBRYOLOGY HISTOLOGY: COMMUNITY

Meiosis + Inclusions MEDICINE
Mitosis Comparison (Lipid, Glycogen, INTRODUCTION TO
With Mitosis Pigments:Melanin, COMMUNITY MEDICINE:
DAY 3 Lipofuscin,Lutein ) &
Self assessment And Cell Cycle Importance of Research
Name Of Secretory Granules
Faculty Name Of Faculty
Name Of Faculty
VENUE VENUE VENUE Name Of Faculty
VENUE
HISTOLOGY:
Cytoskeleton HISTOLOGY
(Microtubules, PATHOLOGY : Epithelium:1 HISTOLOGY BIOCHEMISTRY
Filaments: Adaptations of Types, Epithelium:2 Water: Structure and
DAY 4 Thick, Thin Cellular Growth Location, Types, Location, Dissociation
/Microfilaments, and Differentiation Functions Functions Name Of Faculty
Intermediate) Name Of Faculty Name Of Name Of Faculty VENUE
Name Of Faculty VENUE Faculty VENUE
VENUE VENUE
PATHOLOGY MICROBIOLOGY PHYSIOLOGY:

Cell injury and Basic bacteriology Cell Signaling Mechanisms:1st & 2nd
DAY 5
cell death Name Of Faculty Messengers
Name Of Faculty VENUE Name Of Faculty
VENUE VENUE
HISTOLOGY :
Cell Surface BIOCHEMISTRY
Modification HISTOLOGY: PATHOLOGY
DAY 6 (Microvilli, Cilia, Cell Junctions Morphologic Alterations in Cell Injury Buffers and pH
Flagella) Name Of Faculty Name Of Faculty Name Of Faculty
Name Of Faculty VENUE VENUE VENUE
VENUE
59
Foundation Module Semester- I
Time Table: Third Week
MACROMOLECULES+SKELETAL SYSTEM
Days 8:30- 9:30 9:30-10:30 11:00 -12:00 12:00 -12:45 1.30-3.00
1-Self Study =A
2- MICROBIOLOGY
PRACTICAL: An account
of a Microbiology Lab
MICROBIOLO
BIOCHEMISTRY: BIOCHEMISTRY: Use of microscope for
GY
SELF identification of bacteria and
ASSESSMENT carbohydrates: Carbohydrates: different staining methods
Structure of
Structure, Isomerism and =B Name Of Faculty
3-PATHOLOGY
bacterial cell
DAY 1 Name Of Faculty Classification and Monosaccharide VENUE
PRACTICAL:
Name Of
VENUE Functions Derivatives An introduction to pathology
Faculty
Name Of Faculty Name Of Faculty laboratory =C Name Of
VENUE
VENUE VENUE Faculty
4-HISTOLOGY
VENUE
PRACTICAL:
Epithelium=D Name Of
Faculty
5-Self Study =E
VENUE
BEHAVIORAL HISTOLOGY EMBRYOLOGY : 1-B
SCIENCES gametogenesis:spermatogenesis and
Introduction to 2-C
DAY 2 Exocrine glands spermiogenesis
Behavioral Science Name Of Faculty Name Of Faculty 3-D
web VENUE VENUE 4-E
Name Of Faculty
VENUE 5-A
COMMUNITY BIOCHEMISTR
MEDICINE Y:
1-C
Origin and Amino Acids: PATHOLOGY 2-D
PATHOLOGY
determinants of Structure, Mechanisms of Cell
DAY 3 Injury
Apoptosis: 3-E
disease Classification and Name Of Faculty
Name Of Faculty Functions Name Of Faculty
VENUE
4-A
VENUE Name Of Faculty VENUE 5-B
VENUE
BIOCHEMISTRY HISTOLOGY: EMBRYOLOGY: 1-D
Ogenesis, Prenatal and EMBRYOLOGY
Proteins: Structure,
Classification and Connective Postnatal maturation of Female Reproductive 2-E
DAY 4 Name Of Faculty
Functions Tissue1: oocytes and Organs 3-A
VENUE Components comparison of gametes Name Of Faculty
Name Of Faculty 4-B
Name Of Faculty Name Of Faculty VENUE
VENUE
VENUE VENUE NLH-1 5-C
HISTOLOGY: 10.30-12.00
connective tissue2: GROSS ANATOMY:5groups
PATHOLOGY
classification Bones ,Division and Function of Skeletal System,
Intracellular
DAY 5 description of each
Accumulations
Classification of Bones, Gross Structure of Adult Long
type Bone, Parts of Young Long Bone
Name Of Faculty
VENUE
VENUE VENUE
PATHOLOGY BIOCHEMISTR GROSS ANATOMY 5 groups 1-E

Pathological Y Fatty acids: Bone development (ossification) Blood supply of 2-A
Structure, 3-B
DAY 6 calcification long bone Cartilage Bone markings
Name Of Faculty Classification and Name Of Faculty 4-C
Functions 5-D
VENUE VENUE
Name Of Faculty
VENUE
60
TIME TABLE: FOURTH Week
(SKELETAL SYSTEM/INTRODUCTION TO PHARMACOLOGY)
DAYS 8:30- 9:30 9:30-10:30 11:00 -12:00 12:00 - 1.30-3.00
12:45
1-HISTOLOGY
PRACTICAL: Connective
tissue( loose and dense)
BIOCHEMISTRY Name Of Faculty
2-PATHOLOGY
SELF GROSS ANATOMY VENUE
PRACTICAL: Intracellular
ASSESSMENT Lipids: Structure, 5 GROUPS accumulations & Pathological
DAY 1 Name Of Classification and General Concepts Of calcification (WEBPATH
Faculty Functions Muscles images=B Name Of Faculty
VENUE Name Of Faculty Name Of Faculty 3-CBL=C
VENUE
VENUE VENUE
4- Name Of Faculty
VENUE = Research
Methodology =D
5-SELF STUDY=E
BIOCHEMIST
RY
HISTOLOGY GROSS ANATOMY 1-B
MUSCULAR 5 groups 2-C
Nucleic Acids
DAY 2 TISSUE GENERAL CONCEPTS
Name Of
Name Of Faculty OF JOINTS
3-D
Faculty 4-E
VENUE
VENUE 5-A
GROSS HISTOLOGY 1-C

ANATOMY BIOCHEMISTRY
Extra-cellular
Blood Vascular System, 2-D
DAY 3 Introduction to Capillaries,Arteries,Veins
Lymphoid Matrix 3-E
, Anastomosis
system Name Of Faculty 4-A
Name Of Faculty
Name Of VENUE 5-B
VENUE
Faculty
VENUE HISTOLOGY: 1-D
Lymphoid System BIOCHEMISTRY
EMBRYOLOG I Enzymes: Structure and 2-E
DAY 4 Y Ovarian Cycle Lymph Node, Functions 3-A
Name Of Thymus Name Of Faculty 4-B
Faculty Name Of Faculty VENUE
5-C
VENUE VENUE
EMBRYOLOG HISTOLOGY:
PHARMACOLOGY
Y Female Lymphoid System
Introduction to
Reproductive Ii
DAY 5 Pharmacology
Cycle Tonsil And Spleen
Name Of Faculty
Menstrual Cycle Name Of Faculty
VENUE
Name Of VENUE
Faculty
VENUE
1-E
COMMUNITY PHARMACOLOG 2-A
MEDICINE Y Routes of EMBRYOLOGY 3-B
Health system administration of Transportation Of Ovum 4-C
DAY 6 research drugs. And Fertilization 5-D
Name Of Name Of Faculty
Faculty Name Of Faculty VENUE
VENUE VENUE
61
FOUNDATION MODULETIME TABLE: FIFTH WEEK
REGULATION AND MICRONUTRIENTS
Days 8:30- 9:30 9:30-10:30 11.00-12.45 1:30-3:00
1= A: SKILL LAB : Routes

GROSS ANATOMY Of Administration Of Drugs
5 groups
PHARMACOLOGY
Nervous System
Dosage of drugs, 2= B: HISTOLOGY
Division Cns, Pns PRACTICAL Muscular Tissue
Self Assessment Calculation and clinical
Neurons: Types
application, Therapeutic
DAY 1 Classification Nerve 3= C: DIGITAL LIBRARY
Name Of Faculty index, Preclinical &
(With Its Covering ) &
VENUE clinical trials, bioassays
Myeliz 4= D: BIOCHEMISTRY
Name Of Faculty
VENUE Cell Membrane (tutorial)
VENUE VENUE
5= E: CBL
DAY 2 HOLIDAY
GROSS ANATOMY
BIOCHEMISTRY 5 groups 1-B
BIOCHEMISTRY
Vitamins 2-C
Minerals Typical Spinal Nerve
DAY 3
Name Of Faculty
Name Of Faculty Name Of Faculty 3-D
VENUE VENUE 4-E
VENUE
5-A
PHARMACOLOGY
EMBRYOLOGY 1-C
BIOCHEMISTRY Factors Modifying The 2-D
First Week Of
Energy Flow Within Drug Response
DAY 4 Development After 3-E
The Cell 1
Fertilization 4-A
Name Of Faculty
Name Of Faculty
VENUE
VENUE
Name Of Faculty 5-B
VENUE
COMMUNITY BIOCHEMISTRY 1-D

MEDICINE Energy Flow Within 2-E
DAY 5 Health City The Cell 2 3-A
Name Of Faculty Name Of Faculty 4-B
VENUE VENUE
5-C
1-E
PHARMACOLOGY EMBRYOLOGY 2-A
DAY 6 Pharmacokinetics BIOCHEMISTRY 2nd Week Of 3-B
Absorption Of Drug, Nucleic Acid 2 Development 4-C
Name Of Faculty Name Of Faculty Name Of Faculty
VENUE VENUE VENUE 5-D
62
FOUNDATION MODULE TIME TABLE: SIXTH WEEK
DEVELOPMENT AND GENETICS
Days 8:30- 9:30 9:30-10:30 11.00:-12:45 1:30-3:00
SELF BIOCHEMISTRY
EMBRYOLOGY
ASSESMENT Replication and 3rd week of development, COMMUNITY MEDICINE
DAY 1 TEST Repair gastrulation, Health System Research
Name Of Name Of Faculty formation of primitive streak Name Of Faculty
VENUE
Faculty and notochord VENUE
VENUE 1- A=DIGITAL LIBRARY
2- B= HISTOLOGY
PRACTICAL
PHARMACO
Blood vessels Name Of Faculty
LOGY
VENUE
3- C= PHARMACOLOGY
BIOCHEMISTRY EMBRYOLOGY
Biotransformat TUTORIAL
3rd week of development ii
ion of Dosage of drugs :Calculation
DAY 2 Transcription neurulation and development of
drugs.Phase- Name Of Faculty Name Of Faculty
somites
1& Phase-11 VENUE VENUE
Name Of Faculty
Name Of 4- D= ANATOMY Museum
VENUE
Faculty :models of bones, joints and
VENUE muscles
Name Of Faculty
VENUE
5- E= CBL
BIOCHEMIS PHARMACOLOG 1-B

TRY Y GROSS ANATOMY
Post- Excretion of drugs & Autonomic Nervous System 2-C
DAY 3
Transcriptional factors affecting the Sympathetic 3-D
excretion of drugs.
Modification Name Of Faculty
Name Of Faculty 4-E
Name Of VENUE
VENUE 5-A
Faculty
DAY 4 PATHOLOG BIOCHEMISTRY 1-C
VENUE GROSS ANATOMY
Y Translation And
Post-Translational Autonomic nervous system 2-D
Human
Genetic
Modification Parasympathetic 3-E
Name Of Faculty
Architecture VENUE
Name Of Faculty 4-A
VENUE
Name Of 5-B
Faculty
BIOCHEMIS PHARMACOLOG
VENUE Y 1-D
TRY
Regulation of
Receptor 2-E
classification,
DAY 5 Gene property, Type & 3-A
Mechanism of drug
Expression
actions.
4-B
Name Of Name Of Faculty 5-C
Faculty VENUE
VENUE
BIOCHEMIS PHARMACOLOG PHYSIOLOGY
TRY Y
Physiological overview of 1-E
Signaling
C Mechanisms G- Autonomic nervous system 2-A
DAY 6 Name Of protein coupled Name Of Faculty 3-B
receptors
Faculty Name Of Faculty VENUE 4-C
VENUE VENUE
5-D
63
Foundation Mod 7th Week Time Table
GENETIC DISORDERS
Days 8:30- 9:30 9:30-10:30 11.00:-12:45 1:30-3:00
DAY 1
Self Study Day
A= DIGITAL LIBRARY
GROSSANATOMY 5 B= Self study
MICROBIOLOGY
SELF ASSESMENT batches
TEST Biochemistry Tutorial
Integumentary
DAY 2 Name Of Faculty Bacterial Genetics C= Gene Defects
systemParts, function,
VENUE Name Of Faculty HISTOLOGY PRACTICAL
appendages + fascia D= Skin And Facia
VENUE
VENUE VENUE
E = CBL
PATHOLOGY: PHARMACOLOGY: EMBRYOLOGY
Fourth To Eighth Weeks 1. B
MendelianDisorders Adverse drug
DAY 3 Organogenetic Period Phases 2. C
reactions/Drug-Drug Of Embryonic Development 3. D
Name Of Faculty interactions Name Of Faculty 4. E
VENUE Name Of Faculty VENUE 5. A
VENUE
DAY 4
BS EMBRYOLOGY
12/1 Fourth to Eighth Weeks
1. C
DAY 5 Culture, Organogenetic Period
Highlights of The Fourth 2. D
CulturalInfluenc 3. E
To Eighth Weeks
es, Belief 4. A
Name Of Faculty
Name Of Faculty VENUE 5. B
VENUE
Name Of
BSFaculty EMBRYOLOGY:
PATHOLOGY:
VENUE 1. D
DAY 6 Biochemical and Molecular
Delivery culturally Fetal Period (9th 2. E
Week till birth) Basis of Some
relevant care 3. A
MendelianDisorders
4. B
Name Of Faculty 5. C
Thurs VENUE VENUE
VENUE
64
Foundation Module Time Table: EIGHTH Week
DRUGS AND TERATOGENS 8
Days 8:30- 9:30 9:30-10:30 11.00:-12:45 1:30-3:00
1. E= DIGITAL LIBRARY
-
INTRODUCTI
EMBRYOLO
ON OF 2. A= SELF STUDY
AUTONOMIC GY
NERVOUS Fetal Membranes
SYSTEM. Amnion(includin 3. B= Biochemistry Tutorial
g disorders of PATHOLOGY Gene Defects
amniotic fluid) Chromosomal Disorders Name Of Faculty VENUE
DAY 1 Synthesis, Chorion
release and fate Name Of Faculty
+umbilical cord, VENUE
of Yolk Sac
4. C= HISTOLOGY PRACTICAL Skin
neurotransmitte And Facia
Name Of
rs Name Of Faculty
Faculty
Name Of VENUE
VENUE
Faculty 5. D= CBL
VENUE
PHARMACOLO
GY:
Adrenergic PHARMACOLOGY:
receptor PATHOLOGY
EMBRYOLOGY: Adrenergic receptor antagonist,
DAY 2 agonist,
Placenta classification & Pharmacological
Classification & Single-Gene Disorders
Name Of actions
mechanism of Name Of Faculty
Faculty Name Of Faculty
VENUE action VENUE
VENUE
Name Of
Faculty
VENUE
PHARMACOLO
GY
EMBRYOLOGY EMBRYOLOGY
Cholinergic PHARMACOLOGY
EMBRYOLOGY :
receptor
Multiple PRENATAL
DAY 3 agonist,classifi Cholinergic receptor antagonist,
Teratogenesis pregnancies DIAGNOSIS
cation & classification & clinical application
Name Of Name Of Name Of
mechanism of Name Of Faculty
Faculty Faculty Faculty
action VENUE
VENUE VENUE VENUE
Name Of
Faculty
VENUE
DAY 4
SELF STUDY
DAY 5
DAY 6 MODULE TEST
65
LEARNING OBJECTIVES
At the end of the teaching session the student should be able to achieve the following
objectives:
HISTOLOGY
Fnd1Anh1 INTRODUCTION TO MICROSCOPY
Identify parts of Light Microscope

Discuss the working of Light Microscope
Discuss the magnification of Microscope
Identify different types of Microscopes and their functions
Identify the types of Electron Microscopes (Transmission and Scanning)
Fnd1Anh 2 CELL : INTRODUCTION
Define cell
Recognize various types of cells
Differentiate between eukaryotic and prokaryotic cell
Identify different components of a cell
Fnd1Anh 3 CELL ORGANELLES
Define Organelles
Enumerate cell Organelles
Discuss detailed Structure, Composition and functions of each cell Organelle (
Mitochondria, Ribosomes, Endoplasmic Reticulum, Golgi Complex and Lysosomes)
Explain the Structure and Composition of Cytoplasm and cytosol
Fnd1Anh 4 NUCLEUS
Define nucleus
Describe the structure of eukaryotic nucleus
Identify the features and functions of nuclear membrane, nucleolus, chromatin and
nucleoplasm
Fnd1Anh 5 INCLUSIONS AND SECRETORY GRANULES
Identify Cytoplasmic inclusions with example of each

List the types of Glycogen particles
Differentiate Exogenous and Endogenous pigments
Recognize crystals and crystalloids
66
Fnd1Anh 6 CYTOSKELETON (MICROTUBULES, FILAMENTS: THICK, THIN / INTERMEDIATE
MICROFILAMENTS
Define Cytoskeleton.
Describe the composition and functions of cytoskeleton.
Enumerate the type, distribution and function of Filaments
Describe the details of microtubules
Fnd1Anh7 CELL MEMBRANE
Define cell membrane

Identify the Structure of cell membrane
Recognize the Phospholipids bilayer and its composition
Differentiate between various types of membrane proteins and carbohydrates
with their function.
Identify the Electron microscopic features of cell membrane
Express the Fluid Mosaic Model of cell membrane
Fnd1Anh8 MITOSIS & CELL CYCLE
Identify the steps of Cell division: mitosis

- Prophase
- Pro metaphase
- Metaphase
- Anaphase
- Telophase
Explain the significance of mitosis
Define the cell cycle
Explain the various stages of cell cycle
Recall the events of somatic cell division
Discuss the significance of S phase of cell cycle
Integrate the knowledge of cell cycle to the basis of development of cancer
Fnd1Anh9 EPITHELIUM: 1
Define Epithelium
Discuss general features of Epithelial cells (basal, apical and lateral
surfaces)
Differentiate between basement membrane and basal lamina
Differentiate between simple and stratified epithelia
Identify the different types of Epithelia and their examples
67
Fnd1Anh10 EPITHELIUM: 2
Define Epithelium
Discuss general features of Epithelial cells (basal, apical and lateral
surfaces)
Differentiate between basement membrane and basal lamina
Differentiate between simple and stratified epithelia
Identify the different types of Epithelia and their examples
Fnd1Anh11 CELL SURFACE MODIFICATION

(MICROVILLI, CILIA, FLAGELLA)
Recognize the modification at the different surfaces of a cell

Identify the modifications at the apical surface (microvilli, cilia and stereo
cilia)
State their distribution and significance
Fnd1Anh12 CELL JUNCTION
Define cell junction

Identify the junctions along the lataral and basal surfaces of cells
Discuss the structure and functions of the five main types of cell junction
Recognize various sites of their distribution
Enlist the components of junctional complex
Fnd1Anh13 EXOCRINE GLANDS

Define glands

Discuss the general feature and structure of exocrine glands

Classify exocrine glands
-on the basis of number of cells.
-on the basis of their structure
-on the basis of type of secretion
-on the basis of mode of secretion
Fnd1Anh14 CONNECTIVE TISSUE1: COMPONENTS
Define connective tissue
Differentiate connective from epithelial tissue
Describe the components of connective tissue
-cells
-fibers
-matrix
68
Fnd1Anh15 CONNECTIVE TISSUE 2:
CLASSIFICATION DESCRIPTION OF EACH TYPE
Classify the connective tissue.

Identify the different types of connective tissue under the microscope.
State the distribution of each type
Fnd1Anh16 MUSCULAR TISSUE
Distinguish three types of muscles at the light and electron microscopic levels.
Identify the distinctive features of each type of muscle fiber:
-Smooth
-Skeletal
-Cardiac
Describe the structural basis of muscle striations
Fnd1Anh17 BLOOD VASCULAR SYSTEM, CAPILLARIES,

ARTERIES,VEINS,ANASTOMOSIS
Define the components of blood vascular system.

Recognize General structure of blood vessels.
Discuss Capillaries and their types
Recognize the structure of different types of Arteries
Recognize the structure of different types of Veins
Discuss Microcirculation, Anastomosis and end arteries
Fnd1Anh18 LYMPHOID SYSTEM I

LYMPH NODE, THYMUS
Discuss the overview of lymphatic tissue including MALT
Tell the functions of Lymph node
Describe and Identify the histological features of Lymph node
Discuss the functions of thymus
Describe and Identify the histological features of thymus
Fnd1Anh19 LYMPHOID SYSTEM II

TONSIL AND SPLEEN
Identify the locations of tonsils.

Learn the histological features of tonsils.
Discuss the Functions of tonsils.
Describe the Histological features of spleen.
Know the Functions of spleen.
69
PHYSIOLOGY
Fnd1Phy1 HOMEOSTATIC MECHANISM OF MAJOR FUNCTIONAL SYSTEM
Define Homeostasis
Discuss Control Systems of the Body
Enumerate Examples of Control Mechanisms
Explain Characteristics of Control Systems
Fnd1Phy2 EXTRACELLULAR FLUID AND INTERNAL ENVIORMENT
Define the Extracellular and intracellular fluid

Describe Origin of Nutrients in the Extracellular Fluid
Explain Removal of Metabolic End Products
Explain Exchange of Water, Nutrients, and Other Substances Between the
Blood and Interstitial Fluid-Diffusion Through the Capillary Membrane
Discuss The Interstitium and Interstitial Fluid-Fluid imbalance-edema
Fnd1Phy3 FUNCTIONS OF CELL ORGANELLES

Explain Organization of the Cell
Describe Physical Structure of the Cell
Discuss Functional Systems of the Cell
o Ingestion by the CellEndocytosis
o Digestion of Pinocytosis and Phagocytic
o Foreign Substances Inside the CellFunction of the Lysosomes
o Synthesis and Formation of Cellular-Structures by Endoplasmic
Reticulum and Golgi Apparatus
o Extraction of Energy from NutrientsFunction of the Mitochondria
Fnd1Phy4 TRANSPORT OF SUBSTANCES THROUGH THE CELL MEMBRANE

Discuss the Lipid Barrier of the Cell Membrane
Define simple Diffusion and Diffusion through the Cell Membrane
Define Facilitated Diffusion
Explain the role Cell Membrane Transport Proteins.
Discuss Diffusion through Protein Channels, and Gating of These Channels
Enlist Factors That Affect Net Rate of Diffusion
Describe Osmosis across Selectively Permeable MembranesNet Diffusion
of Water
Fnd1Phy5 ACTIVE TRANSPORT OF SUBSTANCES THROUGH MEMBRANES
Define Primary Active Transport

Enlist examples of primary active transport
Discuss Secondary Active TransportCo-Transport and Counter-
Transport
Describe Active Transport Through Cellular Sheets
70
GROSS ANATOMY
Fnd1Ang2 TERMINOLOGIES: (ANATOMICAL POSITIONS ,TERMS OF POSITIONS ,

ANATOMICAL PLANES)
Define various anatomical positions ( anatomical, supine, prone)

Define various terms of position
Differentiate between the various relative positions
Identify various anatomical plane
Fnd1Ang3 TERMS OF MOVEMENT

Define and Demonstrate the movements occurring at various joints of body
(flexion, extension, abduction,adduction, rotation)
Identify movements occurring at specific joints (pronation, supination,
inversion , eversion)
Identify the planes at which the movements occur
Fnd1Ang4 INTEGUMENTARY SYSTEM

PARTS, FUNCTION, APPENDAGES + FASCIA.
Define the term integumentary system.

Discuss the functions of the skin .
Differentiate between epidermis and dermis.
Discuss the significance of tension lines.
Discuss the main determinant of skin color.
Identify the appendages of the skin
Differentiate between superficial and deep facia
Fnd1Ang5 BONES :DIVISION AND FUNCTION OF SKELETAL SYSTEM
Explain the division and function of skeletal system

Classify bones according to shape and regions.
Identify the parts of adult long bone.
Identify the parts of young long bone.
Fnd1Ang6 BONE DEVELOPMENT (OSSIFICATION):

(BLOOD SUPPLY OF LONG BONE,CARTILAGE, BONE MARKINGS )
Explain the ossification of bone

Identify the centres of ossification and their significance
Distinguish between Intramembranous and endochondral ossification.
Enlist the sources of blood supply of long bones
Identify the bone markings.
List and Identify the types of cartilages
71
Fnd1Ang7 GENERAL CONCEPTS OF MUSCLES:
Enlist the components of muscular system

Classify the muscles according to:
their Shape and
direction of fibers
their action
Express the principles of innervation and blood supply of muscles
Fnd1Ang8 GENERAL CONCEPTS OF JOINTS:
Define the joints

Classify the joints on the basis of uniting material
Define a synovial joint
Enlist the features of synovial joint
Classify Synovial joints on the basis of:
Shape of articulating surfaces
Degree of mobility
Express the principles of innervation and blood supply of synovial joints
Fnd1Ang9 INTRODUCTION TO LYMPHOID SYSTEM:
Define lymphoid /lymphatic system

Define lymphatics and lymph nodes
Describe briefly the structure of lymph node
Enlist various Lymphoid tissues and Lymphoid organs.
Identify large lymphatic channels: right lymphatic duct and thoracic duct
Identify the role of lymphatic system in infections
Identify the role of lymphatics in the spread of cancer
Fnd1Ang10 INTRODUCTION TO NERVOUS SYSTEM

Enlist the basic divisions of Nervous system
Enlist and define the various components of CNS and PNS
Describe the structure of Neuron
Classify neurons on the basis of
o No of processes
o Length of fibers
Define a nerve and its coverings
Differentiate between myelinated and unmyelinated fibres
Enlist various types of Neuroglia and state their functions
Fnd1Ang11 TYPICAL SPINAL NERVE
Define a spinal nerve.

Recognize the spinal nerve as a part of PNS.
Enumerate the spinal nerves in different regions.
72
Identify their location and site of emergence.
Identify various components of a typical spinal nerve.
Recall the fate of rami.
Associate the rami communicans with typical spinal nerve.
Recall the distribution of gray rami.
Fnd1Ang12 AUTONOMIC NERVOUS SYSTEM SYMPATHETIC

Define Autonomic Nervous System
Define sympathetic part of Autonomic Nervous System.
Compare somatic and autonomic systems.
Recognize the components of sympathetic part of nervous system (thoracolumbar
outflow: lateral gray horn, paravertebral sympathetic chain, prevertebral ganglia
and plexuses)
Differentiate between white and gray rami communicans
Describe the different fates (destination) of white and gray rami (preganglionic
and postganglionic fibres)
List the functions
Fnd1Ang13 AUTONOMIC NERVOUS SYSTEM PARASYMPATHETIC
Define parasympathetic part of Autonomic Nervous System.

Recognize the components of parasympathetic part of nervous system
(craniosacral outflow: Parasympathetic Cranial nerve nuclei and Sacral spinal
segments)
Enlist the Parasympathetic ganglia
Describe the pathways of pre and post ganglionic parasympathetic fibres
List the functions
Compare Sympathetic & Parasympathetic Systems.
Fnd1Ang14 FEMALE REPRODUCTIVE ORGANS
Discuss the brief gross anatomy of each part of female genital system
Recognize the different parts of female genital tract and their location in pelvic
cavity
State the blood supply, nerve supply and lymphatic drainage
Mention the microscopic features of each part in relation to ovulation,
menstruation and pregnancy
GENERAL EMBRYOLOGY
Fnd1Ane1 MEIOSIS AND COMPARISON WITH MITOSIS
Define Meiosis
Differentiate first and second meiotic divisions.
State the phases of meiotic divisions.
Justify the importance and result of meiosis in both sexes
Differentiate between mitosis and meiosis.
73
Fnd1Ane2 OVARIAN CYCLE
Define the ovarian cycle

Explain the stages of maturation of primary oocyte to mature ovum after
puberty
Describe the hormonal control (FSH, LH) of ovarian cycle
Mention the liberation of mature ovum into abdominal cavity, formation of
corpus luteum and albican
Fnd1Ane3 FEMALE REPRODUCTIVE CYCLE / MENSTRUAL CYCLE
Define the female reproductive cycle (menstrual cycle)

Discuss its different phases
Interpret the hormonal control of menstrual cycle
Correlate the ovarian cycle and with menstrual cycle
Fnd1 Ane 7-GAMETOGENESIS & SPERMATOGENESIS AND SPERMIOGENESIS
Define gametogenesis
Describe the sequence events of spermatogenesis in the male.
Identify the importance of mitosis and meiosis in spermatogenesis.
List the steps in Spermeogenesis
Differentiate between spermatogenesis and Spermeogenesis
Fnd1 Ane 8 Oogenesis, Prenatal and Postnatal maturation of oocytes and comparison of
gametes
Define the term oogenesis.

Describe the process of oogenesis.
Differentiate between primary and secondary oocytes.
Explain the importance of arrest of division of primary oocyte in prophase
Compare the male and female gametogenesis.
Fnd1 Ane 9 TRANSPORTATION OF OVUM AND FERTILIZATION
Discuss the transport of ovum from the surface of ovary to ampulla of fallopian
tube
List the factors affecting the transport of ovum
Define fertilization
State normal site of fertilization
Describe the results of fertilization
Mentions the factors affecting fertilization
Enumerate the changes that occur in spermatozoa before fertilization
74
Explain the factors affecting penetration of sperm through the zona pellucida for
formation of Pro nuclei
Fnd1 Ane 10 FIRST WEEK OF DEVELOPMENT AFTER FERTILIZATION
Discuss the formation of zygote

Correlate the transport of zygote from ampulla of fallopian tube to the uterine
cavity and cleavage
Explain the formation of blastocyst
Fnd1 Ane11 2ND WEEK OF DEVELOPMENT
Define implantation
State its normal site
Explain the formation of outer and inner cell masses
Discuss the further development of outer cell mass (trophoblast),
Differentiate syncytiotrophoblast and cytotrophoblast with its microscopic
appearance
Describe the process of implantation (day wise change)
State the differentiation of embryonic pole and development of bilminar germ
disc with formation Epiblast and hypoblast, their cavities (amniotic cavity and
primary yolk sac)
Discuss the development of the chorionic sac and formation Primary chorionic villi
Enumerate the abnormal sites for implantation (ectopic pregnancy) and the
different diagnostic tools
Fnd1 Ane12 3RD WEEK OF DEVELOPMENT I, GASTRULATION,

FORMATION OF PRIMITIVE STREAK AND NOTOCHORD
Define the gastrulation ( formation of three germ layers)

Discuss the development of primitive streak and related congenital anomalies
(Sacrococcygeal Teratoma)
Describe the development of notochordal process, notochord canal, prechordal
plate and cloacal membrane
Fnd1 Ane 13 3RD WEEK OF DEVELOPMENT II

NEURULATION AND DEVELOPMENT OF SOMITES
Define Neurulation
List the steps of development of Neural Tube
Enumerate the derivatives of Neural Crest Cells
State the congenital anomalies resulting from abnormal neurulation
Describe the formation of three germ layers
Differentiate three components of Mesoderm (Paraxial, Intermediate and Lateral
plate Mesoderm)
Define Somites
75
Relate the development of Somites with the formation of axial skeleton and
associated structures
Discuss the development of Intraembryonic coelom and primordial CVS
Explain the further development of chorionic villi
Fnd1 Ane14 FOURTH TO EIGHTH WEEKS , ORGANOGENETIC PERIOD
PHASES OF EMBRYONIC DEVELOPMENT
Define the terms used in embryogenesis like growth, morphogenesis and

differentiate
To differentiate these terms
State the folding of embryo in median plane (head and tail folding)
Describe the folding of embryo in horizontal plane (lateral folding)
Enumerate the derivatives of three germ layers
Fnd1 Ane 15 FOURTH TO EIGHTH WEEKS ORGANOGENETIC PERIOD

HIGHLIGHTS OF THE FOURTH TO EIGHTH WEEKS
List the highlights of the period that give rise to all the major organs and systems
List the methods of estimation of embryonic age
Define different terminologies used for the age determination (crown-rump
length and crown-heel length)
Determine gestational age with help of history and calculate expected date of
delivery
Fnd1 Ane 16 FETAL PERIOD (9th WEEK TILL BIRTH)
Define the fetal period

Discuss the factors affecting fetal period
Specify the tissue and organ development week wise
Know the different milestone in development of fetus
Mention the causes of fetal loss
Fnd1 Ane 17 The Fetal Membranes and Placenta

Specify the development and functions of fetal membranes, chorion, amnion, yolk
sac, umbilical cord and allantois.
Discuss the birth injuries related to amniotic fluid.
Know the details of amnion, chorion.
Describe the formation and function of amniotic fluid.
Identify yolk sac and umbilical cord
Fnd1 Ane18 The Placenta

Know the changes occur in the endometrium of mother with formation of
deciduas and decidual reaction
Describe the different types of Chorionic villi
Mention the development of placenta, both the fetal part and maternal part
Describe the functions of placenta
Describe the placental circulation
76
Fnd1 Ane19 MULTIPLE PREGNANCIES
Define the multiple pregnancies
Know the different types of multiple pregnancies
Differences between the mono and dizygotic twins
Specify the risk factors related to multiple pregnancies
Know about conjoined twins and its different types
Fnd1 Ane 20 TERATOGENESIS
Classify the birth defects
Enumerate the causes of birth defects
Know the genetic factor involve in birth defects
Name the environmental causes producing birth defects
Fnd1 Ane 21 Prenatal diagnosis
Define the mechanism of tests of prenatal diagnosis during 1 st trimester
Define the mechanism of tests of prenatal diagnosis during 2 nd trimester
Describe the indications for amniocentesis
BIOCHEMISTRY
Fnd1 Bio 1 EXTRA-CELLULAR MATRIX
Define Extra-cellular matrix

Describe the structure of proteins, carbohydrates and mineral content of ECM.
Describe the functions of various molecules of ECM.
Describe the various forms of Extra-cellular matrix (intercellular space,
subcutaneous tissue, cartilage, bone) w.r.t. the variations in protein
carbohydrates and mineral contents.
Fnd1 Bio 2 Organization of Living System: The Macromolecules

Understand the philosophy and meaning of life
Define level of organization
List the various levels of organizations
Describe Chemical organization of the human body
Describe macromolecules
Relate macro-molecules with different functions
Fnd1 Bio 3 CELL MEMBRANE
Describe the structure of cell membrane

Explain the concept of Fluid Mosaic Model.
Differentiate the structural and functional differences between membrane
peripheral and integral proteins with examples and references.
Explain the role of membrane phospholipids in cell functions (Phosphoinositol
triphosphate, Phosphatidyl choline)
Explain the role of membrane carbohydrates (blood groups, glycocalyx)
Explain the role membrane molecule in intracellular signaling with examples
77
Fnd1 Bio 4 WATER: STRUCTURE AND DISSOCIATION
Describe structure of water

Justify that water is universal solvent.
Justify that water forms the medium of cytosol, ECM and blood.
Discuss the dissociation of water and its contribution in pH.
Fnd1 Bio 5 BUFFERS AND |PH
Define pH
Discuss the hydrogen ion production in the body
Define buffers
Explain the mechanism of action of buffers
Justify that bicarbonate buffer is the major buffer of the body.
Discuss the clinical states of disturbed pH
Fnd1 Bio6 CARBOHYDRATES: STRUCTURE, CLASSIFICATION AND FUNCTIONS
Define carbohydrates
Classify carbohydrates on the basis of functional group and carbohydrate moiety.
Describe the structure of mono, di and polysaccharides
Discuss the biomedical importance of mono, di and polysaccharides
Describe the functions of mono, di and polysaccharides
Fnd1 Bio7 CARBOHYDRATES: ISOMERISM AND MONOSACCHARIDE DERIVATIVES
Explain isomerism in carbohydrates

Discuss biomedical importance
Describe the monosaccharide derivatives (sugar acids, sugar alcohols, amino-
sugars and deoxysugars)
Discuss the clinical importance of monosaccharide derivative (GAGs,
detoxification, cataract, diabetes mellitus, hexosamines, DNA)
Fnd1 Bio8 AMINO ACIDS: STRUCTURE, CLASSIFICATION AND FUNCTIONS
Define amino acids

Classify amino acids on the basis of nutrition, R group and solubility.
Describe a zwitter ion and its significance
Describe the functions of amino acids
Explain the formation of peptide bond
Justify that peptide bond is a modified amide bond.
78
Fnd1 Bio9 PROTEINS: STRUCTURE, CLASSIFICATION AND FUNCTIONS
Define proteins
Justify that protein chains have a direction from amino to carboxylic end.
Differentiate between configuration and confirmation w.r.t proteins
Classify proteins on the basis of nutrition, shape, solubility and functions
Justify that function of protein depends upon the structure w.r.t. (cell membrane
proteins, cytoskeleton, hormones, enzymes, skin, and hair).
Fnd1 Bio10 FATTY ACIDS: STRUCTURE, CLASSIFICATION AND FUNCTIONS
Define fatty acids

Describe the structure of fatty acids
Classify fatty acids on the basis of saturation and nutrition
Describe the functions of fatty acids
Discuss the clinical significance of fatty acids in health and disease
Fnd1 Bio11 LIPIDS: STRUCTURE, CLASSIFICATION AND FUNCTIONS
Define lipids
Classify lipids
Describe the functions of various classes of lipids.
Justify that cell membrane is made up of phospholipids
Justify that milk is needed for post natal development of brain (phospholipids,
glycolipids, sphingolipids).
Discuss the clinical significance of lipids (obesity, diabetes mellitus, cardiovascular
diseases, vitamin D deficiency, hypertension, storage diseases)
Fnd1 Bio12 EXPLAIN THE PROCESS OF ENERGY FLOW WITHIN THE CELL.
Define bioenergetics.
Define energy, energy carriers and low, moderate and high energy compounds.
Differentiate between oxidation and reduction.
Discuss the methods of electron flow from substrate to oxygen (Hydronium ion,
hydrogen atom, free electrons and oxygen).
Enumerate the substrates used for energy.
Justify the role of mitochondria in generation of energy (structure, enzymes in
membranes and matrix
, own DNA).
List the enzymes of electron transport chain in the increasing redox potential
order.
Justify that electron transport chain is also termed as respiratory chain.
Explain that oxidation is linked with phosphorylation of ATP
79
Fnd1 Bio13 Describe the structure and functions of nucleic acid and their relationship in
central dogma.
Define nucleic acids
Discuss the structure and types of nucleic acids DNA and RNA
Differentiate between DNA and RNA
Define central dogma and justify its relation with living state.
Fnd1 Bio14 NUCLEOTIDES: STRUCTURE, CLASSIFICATION AND FUNCTIONS
Describe nitrogenous bases present in the nucleic acids

Describe the structure of nucleoside and nucleotides
Discuss the functions of nucleotides (energy carrier, coenzymes, electron carrier,
metabolite activator, nucleic acids)
Explain polymerization of nucleotides via 3-5 phosphodiester bonds
Justify that the nucleotide polymers have a direction fro 5 to 3.
Fnd1 Bio15 EXPLAIN THE PROCESS OF REPLICATION AND REPAIR.REPLICATION AND REPAIR
Define replication.
List the requirements for replication
Deduce the appropriate time for replication in cell cycle.
State the theories of replication
Explain the process of replication
Justify the need for RNA primer in replication
Differentiate the process of replication on leading and lagging strand
Differentiate between DNA polymerase I and III.
Justify that replication is a flawless process (proofreading activity).
Explain the processes of repair in DNA replication and relate this with disease
processes like xeroderma pigmentosa.
Differentiate the replication of DNA in pro and eukaryotes
Fnd1 Bio16 EXPLAIN THE PROCESS OF TRANSCRIPTION AND POST TRANSCRIPTIONAL

MODIFICATION TRANSCRIPTION
Define transcription
Define transcription factors.
Describe the properties of RNA polymerase
Differentiate between coding and non-coding strand of DNA
List the requirements for transcription.
Explain the process of transcription
Discuss the aberrations in transcription.
Differentiate the process of transcription in pro and eukaryotes.
80
Fnd1 Bio17 EXPLAIN THE PROCESS OF TRANSCRIPTION AND POST TRANSCRIPTIONAL
MODIFICATION POST-TRANSCRIPTIONAL MODIFICATION
Define posttranscriptional modification
Define introns and exons.
Describe the structure of primary transcript
Describe the post-transcriptional modifications of the primary transcript with
their significance.
Discuss the clinical significance of the abnormal post-transcriptioonal
modifications.
Fnd1 Bio18 EXPLAIN THE PROCESS OF TRANSLATION AND POST TRANSLATION

MODIFICATION TRANSLATION AND POST-TRANSLATIONAL MODIFICATION
Define and Describe characteristics of genetic code.
Justify that language of nucleotides change to language of amino acids to exhibit
phenotype.
Define mutations and its types (missense, nonsense, silent, frameshift, non-
frameshift, deletions and insertions)
Define protein synthesis as the process of translation.
List and describe the requirements for translation.
Explain the steps of translation.
Discuss regulation of translation
Describe the post-translational modification of proteins with examples
Fnd1 Bio19 DISCUSS REGULATION OF GENE EXPRESSION REGULATION OF GENE EXPRESSION
Define the term regulation

Recognize that all humans carry the same set of genes yet they are different
from each other.
Justify that the genome is selectively expressed in each individual influenced
by various genetic and environmental factors
Describe the structure of an operon.
Explain the process of regulation of gene expression both in pro and
eukaryotes
Fnd1 Bio20 DESCRIBE MUTATIONS, GENE DEFECTS METHODS OF TRANSMISSION OF

GENETIC DISEASES AND RELATE THEM WITH DISEASES (DOWNS SYNDROME,
TURNERS, KLINEFELTERS, SICKLE CELL ANEMIA, CYSTIC FIBROSIS, X-LINKED
DISEASES).
Describe various mutations in the genetic code

Define gene, locus, allele, homozygous, heterozygous, autosomal and X-
linked, dominant and recessive.)
Differentiate between single and multiple gene defects.
81
Explain the methods of transmission of genetically transmitted diseases
(autosomal and X linked dominant and recessive).
Draw the pedigree of the families affected by genetic diseases.
Calculate the probability of the diseased offspring in autosomal and X- linked,
dominant and recessive diseased family
Relate the mutations in Downs syndrome Turners, Klinefelters, sickle cell
anemia, cystic fibrosis, X-linked diseases
Fnd1 Bio21 CLASSIFY ENZYMES AND EXPLAIN THEIR MECHANISM OF ACTION
Define enzymes and related terms (holoenzyme, apoenzyme, prosthetic

group, isoenzymes, active site, allosteric site, specificity, enzyme activity,
regulation, location)
Describe the structure of enzymes.
Define energy of activation and energy barrier.
Justify that enzymes provide an alternate pathway with lower energy barrier.
Describe Km
Justify that enzyme affinity and Km are reciprocally related.
Discuss the clinical significance of Km (hexokinase and glucokinase)
Discuss the general clinical significance of enzymes.
Fnd1 Bio22 DESCRIBE CLASSIFICATION AND FUNCTIONS OF VITAMINS AND MINERALS

WITH THEIR DEFICIENCY AND TOXIC CONSEQUENCES.
VITAMINS AND MINERALS
Define micronutrients
Identify vitamins and minerals as micronutrients.
Classify vitamins on the basis of solubility
Describe the general characteristics of water and lipid soluble vitamins in
relation to sources, RDA, digestion and absorption, transport in blood, storage
and excretion, functions, toxicity and deficiency states.
Classify and list minerals as macro and micro-minerals.
Describe the sources and functions of the macro and micro-minerals
PATHOLOGY
Fnd1 Pth1 INTRODUCTION OF PATHOLOGY
Define pathology
Briefly describe the outline of cellular response to stress and injury
Enumerate the types of adaptations of Cellular Growth and
Differentiation
82
Fnd1 Pth2 ADAPTATIONS OF CELLULAR GROWTH AND DIFFERENTIATION
Define/Compare Hypertrophy, Hyperplasia, Atrophy and Metaplasia.

Enlist physiological and pathological mechanisms of above mentioned types of
adaptation.
Fnd1 Pth3 CELL INJURY AND CELL DEATH:
Define and briefly describe the terms: Reversible cell injury and Cell death
Enumerate the Causes of Cell Injury
Describes the sequential morphologic changes in Cell Injury that end in cell
death or apoptosis
Fnd1 Pth4 MORPHOLOGIC ALTERATIONS IN CELL INJURY
Differentiate between Necrosis and Apoptosis

Describe the light and electron microscopic morphology of Reversible injury.
Describe the nuclear and cytoplasmic features of necrosis.
Define and briefly describe the Patterns of Tissue Necrosis including:
o Coagulative necrosis
o Liquefactive necrosis
o Gangrenous necrosis
o Caseous necrosis
o Fat necrosis
o Fibrinoid necrosis
Fnd1 Pth5 MECHANISMS OF CELL INJURY
Discuss the mechanisms of Cell Injury in terms of :

Explain ischemic injury, reperfusion injury and toxic injury with the help of
selected Clinical examples Cell Injury and Necrosis
Fnd1 Pth6 APOPTOSIS:
Define Apoptosis
Enumerate pathological and physiological Causes of Apoptosis
Describe Biochemical Features and Mechanism of Apoptosis
Summarize the role of Apoptosis in health and disease
PATHOLOGIC CALCIFICATION
Fnd1 Pth7
Define and describe Pathologic Calcification.
Differentiate between Dystrophic calcification and Metastatic calcification
Discuss events in Cellular Aging
83
Fnd1 Pth8 INTRACELLULAR ACCUMULATIONS
Discuss the role of Intracellular Accumulations in metabolic derangements of cell.

Define and briefly describe the terms:
o Steatosis (Fatty Change)
o Cholesterol and Cholesterol Esters
o Proteins component accumulation
o Hyaline changes
o Pigments
o Glycogens
Fnd1 Pth9 INTRODUCTION OF PATHOLOGY LABORATORY

Define pathology
Explain the various components of pathology namely microbiology & histopathology
Fnd1 Pth10 HUMAN GENETIC ARCHITECTURE

Review Genes and Human Diseases
Define Mutations
Review principals relating to the effects of gene mutations including: Point
mutations within coding sequences
o Mutations within noncoding sequences
o Deletions and insertions:
o Trinucleotide-repeat mutations
Fnd1 Pth11 MENDELIAN DISORDERS
Discuss the postulates of Mendelian Disorders

Explore the pattern of inheritance in Autosomal Dominant Disorders, Autosomal
Recessive Disorders and X-Linked Disorders
List the examples of autosomal and x linked disorders
Fnd1 Pth12 BIOCHEMICAL AND MOLECULAR BASIS OF SOME MENDELIAN DISORDERS
Enumerate the biochemical and molecular basis of single gene (Mendelian)

disorders.
Describe the pathogenesis and morphology of Marfan syndrome, Familial
Hypercholesterolemia, Lysosomal Storage Diseases, Niemann-Pick disease,
Gaucher disease, Glycogen Storage Diseases.
Fnd1 Pth13 CHROMOSOMAL DISORDERS
Describe the normal Karyotype

Define various types of structural abnormalities of chromosomes including:
Deletion, ring chromosome, Inversion, Isochromosome and Translocations.
Discuss the cytogenetic disorder involving autosomes
Trisomy 21 (Down Syndrome)
84
Discuss the cytogenetic disorder involving sex chromosomes (Klinefelter
Syndrome, Turner Syndrome)
Fnd1 Pth14 SINGLE-GENE DISORDERS

Define the term Single-Gene Disorders with Nonclassic Inheritance
Classify and briefly describe the following:
o Diseases caused by trinucleotide-repeat mutations
o Disorders caused by mutations in mitochondrial genes
o Disorders associated with genomic imprinting
o Disorders associated with gonadal mosaicism
Fnd1 Pth15 MOLECULAR DIAGNOSIS OF GENETIC DISEASES
Discuss the role of Molecular Diagnosis of Genetic Diseases especially germline

mutations and acquired genetic alterations.
List the indications for Prenatal and Postnatal genetic analysis, Diagnosis and
management of cancer and infectious disease
Describe the significance of PCR analysis, Southern Blotting, Fluorescence in Situ
Hybridization, Array-Based Comparative Genomic Hybridization as future
diagnostic tools
MICROBIOLOGY AND BASIC BACTERIOLOGY
Fnd1 Mic1 BASIC BACTERIOLOGY
Define Microbiology
Briefly describe the different fields of microbiology and their role in Diagnosis
of infectious diseases
Differentiate between eukaryote and prokaryote cells and the importance of the
morphological difference in disease and diagnosis of infections
Fnd1 Mic2 STRUCTURE OF BACTERIAL CELL AND SPECIALIZED STRUCTURES

Describe the important components of a typical bacterial cell
State the differentiating characteristics of gram positive and gram negative
bacteria and its importance in diagnosis and vaccination .
Enlist the specialized structure of bacterial cell and their role in disease.
Fnd1 Mic3 BACTERIAL GENETICS

Enlist the methods of DNA transfer in microorganisms
State the significance of DNA transfer in drug resistance
Enlist and describe the types of mutations in bacteria.
Describe the process of lysogeny .
Describe the role of mutations in drug resistance in infectious diseases.
85
PHARMACOLOGY
Fnd1 Pha1 INTRODUCTION TO PHARMACOLOGY
Define the terms:
o Pharmacology branches,
o Drug, poison,
o Pharmacodynamics
o Pharmacokinetics.
o What are the Sources of drug,
o Application of basic principles in selected examples of drug use,
o Importance of Pharmacopeias
o New challenges in Pharmacogenetics
Principles
Ethnic differences
Specific examples of genetically variable enzymes
CYP2D6, CYP2C9, CYP2C19
Fnd1 Pha2 ROUTES OF ADMINISTRATION OF DRUGS.

Approach of different route of administration
Advantages / Disadvantages of different routes of administration.
Fnd1 Pha3 DOSAGE OF DRUGS, CALCULATION AND CLINICAL APPLICATION THERAPEUTIC
INDEX, PRE-CLINICAL & CLINICAL TRIALS, BIOASSAYS.
Describe different dosage forms, their correct names and special characteristics.
Define the terms ED50, LD50, TD50 and Therapeutic index.
Describe what is meant by the term Therapeutic Window.
Explain how a quantal dose-response curve is constructed
Fnd1 Pha4 FACTORS MODIFYING THE DRUG RESPONSE

Describe how different dosage forms alter the absorption, distribution, onset of
duration of action of drugs.
Fnd1 Pha5 PHARMACOKINETICS: ABSORPTION OF DRUG, &DISTRIBUTION OF DRUGS

Explain what is meant by the term drug disposition.
Explain the drug properties facilitate absorption.
Describe factors affecting the absorption of drugs
Discuss which biological properties that facilitate absorption.
Explain the mechanism of pH-dependent ion trapping with respect to accumulation of
drugs.
Explain which chemical properties make a drug more water soluble.
Explain which chemical properties make a drug more lipid soluble.
Define plasma half life, its clinical significance & factors affecting them.
Discuss protein binding and the effect of concomitant administration of two protein-
binding drugs on drug effect.
Discuss the impact of drug distribution and redistribution on drug action.
86
Fnd1 Pha6 BIOTRANSFORMATION OF DRUGS.PHASE-1& PHASE-11
Explain the principle of the chemical defense hypothesis.

Explain what is meant by the term drug metabolism.
List the major mechanisms responsible for drug metabolism.
Describe the major enzyme systems in the body that are responsible for
oxidation, reduction and/or hydrolysis of selective pharmacological agents.
Describe the basic principles of how drug metabolism alters drug action.
Define cytochrome p-450.
Explain how drugs are chemically altered by cytochrome p-450.
Explain the rate limiting step in the general non-specific pathway for drug
metabolism in the liver.
Discuss the difference between acute and chronic drug treatment with respect to
drug metabolism by the liver.
Explain how drug-induced enzyme induction and inhibition can alter responses to
drugs.
Discuss the basic clinical interactions that can result from changes in drug
metabolism during co-administration of drugs.
Fnd1 Pha7 EXCRETION OF DRUGS & FACTORS AFFECTING THE EXCRETION OF DRUGS.
Explain the basic principles by which drugs are excreted from the body
What are routes of drug elimination?
Fnd1 Pha8 ADVERSE DRUG REACTIONS/DRUG-DRUG INTERACTIONS
Define adverse drug reactions

Differentiate between side/ untoward & toxic effects
List the different types of adverse effects
Define tolerance & describe its types
Define hypersensitivity and explain its types
Explain drug tolerance
Describe the various systemic adverse effects
Fnd1 Pha9 RECEPTOR CLASSIFICATION, PROPERTY, TYPE & MECHANISM OF DRUG

ACTIONS.
Describe the two primary properties of a drug receptor, and how a receptor
differs from an inert binding site.
Define the following drug properties: agonist, antagonist, partial agonist,
affinity, efficacy, potency.
Describe a typical dose-response curve for a drug, and label the positions on
the curve that are used to define drug potency and efficacy.
Explain the difference between selectivity and specificity of drug effect, and
which is more commonly observed.
Explain what is meant by additive, Potentiative and synergistic drug effects.
87
Fnd1 Pha10 SIGNALING MECHANISMS G-PROTEIN COUPLED RECEPTORS.
Describe several different signal transduction mechanisms by which agonists exert

their effects.
COMMUNITY MEDICINE
Fnd1 Com1 INTRODUCTION TO PUBLIC HEALTH AND COMMUNITY MEDICINE
& HISTORICAL DEVELOPMENT OF PUBLIC HEALTH
Descirbe basic definitions
Discuss concept of c.o.m.e (community oriented medical education)
Define comprehensive health care
Describe historical development of public health
Describe development of public health in indo-pakistan
Discuss health plans and social action programs
Discuss major health problems
Discuss who as international organization
Fnd1 Com2 ORIGIN AND DETERMINANTS OF DISEASE

Discuss mckeons concept
Define determinants and types of determinants
Discuss societies in transition
Fnd1 Com3 HEALTH SYSTEMS

Describe health systems development
Explain situation analysis by studying health indicators &to identify health
needs
Enlist health systems problems
Define equity, effectiveness
Enlist public health engineering, financial and organizational problems
Enlist problems of health planning, evaluation and research
Identify services and resources, health facilities and health manpower
Describe major problems of rural and urban health areas of Pakistan
Fnd1 Com4 HEALTHY CITY

Describe the concept of healthy cities by WHO
88
BEHAVORIAL SCIENCES
Fnd1Beh1 Introduction to Behavioral Science web

Discuss the relevance of behavioral sciences in medicine
Enumerate new holistic pattern of medical education
Describe difference b/w curriculum traditional & new holistic medical
education
Explain WHOs health definition demand holistic approach
Fnd1Beh 2 Culture, Cultural Influences, Belief

Discuss concept of sociology and anthropology and their importance in
medicine.
Describe culture and subculture and their influences.
Discuss evolution of culture as dynamic processes.
Discuss concept of Belief values and norms and their impact on clinical
practice.
Evaluate the attitude of physicians toward culture.
Fnd1Beh 3 Delivery culturally relevant care

Evaluate the influence of Socio-cultural Factors on Therapeutics
Describe the process of Cultural Assessment
Evaluate the role of holistic doctor
Fnd1Beh 4 Value & Attitudinal Transformation

Identify, explore and clarify Values, Attitudes and Transformation
To understand Value clarification and Attitudinal transformation framework
To understand the difference between sex and gender (gender identity,
gender roles, gender wheel, mainstreaming of gender in health system, stigma
and discrimination)
To understand and clarify the concept of basic SR rights (ICPD, MDGs,
Declarations and legislations)
89
CASE BASED LEARNING
1. CBL :1
What is menstrual cycle.
What are the phases of menstrual cycle.
What are the hormones released during the cycle how they effect and
controlled.
Explain histological changes in ovary and endometrium.
2. CBL :2
Define Osmosis and how hypernatremia disturb the osmolarity and cellular
function
Enumerate the Factors affecting the movement of water and electrolytes
across cell membrane (Between extracellular and intracellular compartment )
Enumerate the causes of HypervolemicHypernatremia ,
IsovolemicHypernatremia and HypovolemicHypernatremia
How homeostasis is achieved if water and electrolytes are distrubed
3. CBL :3
Structure, function and different parts of cell.
Importance of cell membrane in regulating various function and defects in
disease states.
Importance of cell nucleus in defining cell function and determining
phenotype and genotype of the species.
Structure, number and types of chromosomes.
Effects of Chromosomal anomalies on gross appearance and physiological
functions of human body
Clinical feature of this syndrome and name it.
Social and ethical issues associated with this syndrome.
Other syndromes of numerical and structural chromosomal abnormalities.
4. CBL :4
Define about twin pregnancy.
Classify the twin pregnancy on the basis of fetal membranes.
Describe the predisposing factor leading to twin pregnancy
Explain the types and complications of twin pregnancy.
90
LEARNING OBJECTIVE OF SKILL LAB CURRICULUM
I. First aid Skills part 1 (bleeding, soft tissue injuries)
II. First aid Skills part 2 (burns, fractures, vertebral injury)
Assemble a First Aid Kit with at least twelve essential contents.

Demonstrate appropriate communication skills while handling a patient
requiring first aid.(especially reassurance to patient)
Following five common injuries will be addressed:-

I- Bleeding
Demonstrate the appropriate methods of managing external bleeding. (Direct
pressure, compressing pressure points, elevation).
II- Soft Tissue Injuries
Demonstrate proper management of wounds including assessment, cleaning
and dressing (head, forearm and hand, leg and ankle).
III. Vertebral column Injury
Demonstrate correct rolls, moves, and lifts in transporting a patient to avoid spinal
cord injury (log roll, spine stabilization)
IV. Bony Injuries (Fractures)
Demonstrate the correct method of splinting fractures in the leg and arm.
V. Burns
Demonstrate the correct method of first aid management of burns.
91
RESEARCH METHODOLOGY
Fnd1Res 1Topic Selection
Describe what type of research can be feasible at beginning of undergraduate level

Select a good topic for their research within their own resources and limitations
Fnd1Res 2 Objective Writing
Define objective of a scientific study

Write a proper study objective
Describe different verbs used in objective writing
Fnd1Res 3 Questionnaire Making
What is a questionnaire
Characteristics of good questionnaire
Close ended and Open ended questions
Develop a good study questionnaire
Fnd1Res 4 Literature Search
Describe how to conduct a good literature search

Describe national online resources
Search in different International online resources
Fnd1Res 5 Study Designs
Different type of study designs

Advantages and disadvantages of study designs
92
TOTAL #Roun
WEEK 1st 2nd 3rd 4th 5th 6th 7th 8th Including(pr ***
CREDIT d of
HOURS %for
act)
PAPER
GEN 24 13.85 1
6 - 3.25 4.5 3.5 5 1.75 - 1.5 14
ANAT.
EMBR - 1 3.5 3.75 2.75 3.5 3.75 4.75 23 13.27

1.43 13
HISTO 7.75 6.5 4.5 6.25 1.5 1.5 1.5 - 29.5 17.02 1.37
17
(7.5) (0.156)
PHYSIO 6.5 1.5 - - - 1.75 - - 9.75 5.627

0.60 6
BIOCHEM 1.5 3 4.75 4.75 6.5 6 1.5 - 28 16.16

1.75 16
PHARM - - - 2.75 3.75 5.5 1 6 19 10.96 1.09

11
(1.5) (0.031)
PATHO 1 3.75 5.25 1.5 - 1 2.75 3.75 10.96 1.0

19 (3) 11
0.0625
MICRO - 1 2.5 - - - 1 - 4.5 2.59 0.18

4
(1.5) (0.031)
COM.MED - 1.5 1 1 1 1.5 1 - 7 4.04

0.43 4
BEH.SCI - - 1 - - - 1 - 2 Fnd15
0.12 1
RES.METH - - - 1.5 1.5 1.5 1.5 - 6 3.46

0.38 3
SKILLS - - - - 1.5 - - - (1.5) 0.86

(0.031) -
Total 1 22.75 18.25 25.75 25.75 22 27.25 16.75 14.75 173.25 100
10.139 100
Total 2 for 6 -
- - - 1.5 1.5 1.5 1.5 - -
III A (CBL)
93
FOUNDATION MODULE
(SEMESTER 1)
SUMMATIVE ASSESMENT
THEORY

SEMESTER EXAM
ATP 25
PAPER-I
One best Questions 80%
20
based on CBL
Total 100
MODULE EXAM
EMQs 10
ATP 20
MODULE PAPER 20%
One best Questions
20
based on CBL
Total 100
STRUCTURED VIVA

ASSESMENT
SUMMATIVE
SEMESTER
EXAM
See Semester
PAPER-III A Structured viva
Assessment Plan
ASSESMENT TOOLS
ASSESME
SEMESTE
SUMMATI
R EXAM
Feedback Given to the

VE
NT
ASSESMENT DURING CBL SESSION

Student by Facilitator
NOTE: Paper II & IIIB of Semester 1 Examination are Based on Blood Module.
94
CREDIT HOURS
SEMESTER I
FOUNDATION MODULE
I 6
Foundation
III A 3
95
HEMATOLOGY MODULE
HEM 1
Semester 1
First Year MBBS
96
5 YEAR CURRICULAR ORGANIZATION
SPIRAL SEM MODULES

II

4 Week
wks
Second th
Spiral th
Trauma, 6 week
3 week 8 Weeks
/ Burns 2 wk
2 Weeks
th
th
Clinical Rotation 8:30 to 1:00 (with Ambulatory, Clinical Rotation 8:30 to 1:00
Emergency, Intensive care) (Inpatient, Ambulatory, Emergency, Intensive care and
PARALLEL THEMES:
97
MODULE COMMITTEE:
1. Dr. Naheed Khan, Associate Professor of Anatomy (Focal Person) DUHS

2. Prof. Nighat Rukhsana, Professor of Physiology DUHS
3. Prof. MahmoodHasan, Professor of Pathology DUHS
4. Dr. MahayRookh, Associate Professor of Pharmacology DUHS
5. Dr. NadeemAlam, Associate Professor of Biochemistry DUHS
6. Prof. Mohammad Akber Agha, Professor of Pathology DUHS
7. Dr. YasmeenTaj, Associate Professor of Pathology DUHS
8. Prof. RazaurRehman, Professor Psychiatry Department DUHS
9. Prof. NighatNisar, Professor of Community Medicine DUHS
10. Dr Rashid Qadeer, Associate Professor of Medicine DUHS
Documented and Coordinated by:
DR. SABAHAT ZAIDI
Reviewed by:
Module committee
98
RATIONALE
Knowledge of blood, immunity and inflammation is essential, as blood is

responsible for the supply of micro-nutrients, O2 delivery to the tissues and
maintenance of homeostasis and body responses and defense mechanisms
against injurious agents and various diseases encountered in daily life.
Terminal Objective
Medical graduate after completion of 5 years training program should be able

to:
Describe the composition of blood in relation to its biochemistry and

physiology
Define anemia and its pathophysiology.
Classify different types of anemias on the basis of its pathophysiology
Recognize ABO/RH blood grouping system
Practice history taking of a patient presented with blood disorders
Explain hemostatsis and roll of thrombolysis
Describe pathophysiology of bleeding disorders & identify its different
types.
Identify role of pharmacology in anemia and bleeding disorders
Define and explain research methadology.
Identify and describe immunology on the basis of its pathophysiology
Enlist pharmaceutical agents used in different immunological disorders
99
Lectures
Demo:
Tutorials
Practical
CBL / SBL
Self Study
Library
Digital
One Best, EMQS

Skills Lab
ATP
viva
SUBJECT Topic / Content
Objectives
Assesment
HEM 1 Ane-1: 1.75
Embryological development of
* *
ANATOMY
blood elements. Hematogenesis
HEM 1 Anh 1 Histology of 1.5

ANATOMY blood
* * *
HEM 1 Phy 1 Composition of 1

Recognize the
blood:cellular components
* * *
structure of
hAnematopoietic
tissues and HEM 1 Phy 2 Maturation of 1.75
mechanism of
PHYSIOLOGY
RBCs. Regulation of
* *
hAnematopoesis erythropoiesis
HEM 1 Phy 3 Peripheral blood 1.5

film
* * *
HEM 1 Bio 1 Composition of 1

BIOCHEMISTRY blood: plasma components of
* *
protein
HEM 1 Bio 2 Synthesis,structure & 2

functions of Hb, oxygen
*
Justify that the
basic structure of dissociation curve
Hemoglobin is BIOCHEMISTRY
essential for HEM 1 Bio 3 Iron metabolism 1
RBCs normal
* *
function
HEM 1 Bio 4 Vit. B 12/Folic acid/ 1
B6
* *
HEM 1 Phy 4 classification of 1.75
anemia and significance of red
* *
Know the PHYSIOLOGY
cell indices
classification of
anemia & HEM 1 Pth 1 Anemia of 1
differentiate the diminished
different types PATHOLOGY
erythropoeisis(megaloblastic/iron
of anemias on
def anAnemia,aplastic
the bassis of
pathophysiology anAnemia)
HEM 1 Phy 5 Hemolysis and 1
PHYSIOLOGY
hemolytic anemias
* *
100
Lectures
Demo:
Tutorials
Practical
CBL / SBL
Self Study
Library
Digital
One Best, EMQS

Skills Lab
ATP
viva
Objectives
Assesment
HEM 1 Pth 2 Bone marrow 1.75
Changes with ages and disease
* * *
(Hemopoisis, Aplastic Anemia)
HEM 1 Med 1 History and 1
MEDICINE
clinical findings in an anemic
* * *
patient
INTEGRATED HEM 1 Cbl 1 Nutritional anemia 1.75
LEARNING (CBL)
*
HEM 1 Pth 3 Hemolytic 1
Explain the anAnemia(hereditary
* * *
PATHOLOGY
Mechanism of spherocytosis,G6PD def,Sickle
corpuscular and cell disease)
extra
corpuscular
in
HEMan 1anemic patientused in
Pha 1 Agents 1
Hemolytic
PHARMACOLOGY
Anemias: Hematopoietic ,
* *
anemia Growth factors
HEM 1 Bio 5 Abnormalities of Hb 1.75
synthesis, porphyria ad its
* *
diffferent types Variants of
BIOCHEMISTRY hemoglobin
HEM 1 Bio 6 Heme Degradation
and related disorders and
* *
Explain the
mechanism of hyperbilirubinemia
qualitative and
HEM 1 Bio 7 Hemoglobinopathies 1
quantitative
and Thalassemia
* *
disorders of
R.B.C. (Hyper-
bilirubinemia) HEM 1 Pth 4 Thalassemia 1
Explain the
PATHOLOGY
syndrome
* *
mechanism of
HEM 1 Bio 8 Hemoglobin 1.75
qualitative and
quantitative
BIOCHEMISTRY
electrophoresis
* * *
disorders of INTEGRATED HEM 1 Cbl 2 Hemoglobinopathies 1.75
R.B.C. (Hyper-
LEARNING (CBL)
* |*
bilirubinemia)
1
HEM 1 Phy 6 Hemostasis and * *
Role of thrombocytes
PHYSIOLOGY 1.5
Understand the
HEM 1 Phy 7 Clotting cascade * * *
and bleeding disorders
mechanism of
hemeostasis, 1
explain the role
HEM 1 Phy 8 Fibrinolytic * *
mechanism
of platelets in
homeostasis and HEM 1 Bio 9 Vitamin K and its 1
coagulation BIOCHEMISTRY disorders
* *
HEM 1 Pth 5 Heamorrhagic and 1

PATHOLOGY thromboembolic conditions
* *
101
Lectures
Demo:
Tutorials
Practical
CBL / SBL
Self Study
Library
Digital
One Best, EMQS

Skills Lab
ATP
viva
Objectives
Assesment
HEM 1 Pha 2 Coagulants & 1
PHARMACOLOGY
Anticoagulants
* *
HEM 1 Pth 6 Bleeding diathesis 1

secondary to platelet disorders
* *
PATHOLOGY
HEM 1 Pth 7 Clotting factors 1
related diseases + factor VIII,IX
* *
Deficiency diseases
PHARMACOLOGY HEM 1 Pha 3 Thrombolytics / 1.5

Fibrinolytics+antiplatelet drugs
* *
1.5
HEM 1 Phy 9 Bleeding time & * *
PHYSIOLOGY clotting time
HEM 1 Med 2 History, 1.5
MEDICINE Examination and Management
* *
of a patient with bleeding
Disorder
INTEGRATED HEM 1 Cbl 3 Thrombocytopenic 1.75
LEARNING (CBL) purpura
* *
Lectures
Demo:
Tutorials
Practical
CBL/SBL
Self Study
Library
Digital
BCQs,SEQs,
Lab
EMQS
Skills
ATP
viva
Objectives
1
Describe the
PHYSIOLOGY
HEM 1 Phy 10 blood goups * A *
different Abo/Rh system/ erythroblastosis
blood groups fetalis
1.75
HEM 1 Phy 11 Blood grouping and * * *
cross matching
Comprehend HEM 1 Pth 8 Indications of Blood 1
the Transfusion and Transfusion
* *
requirements PATHOLOGY
Reactions + Blood Banking
of transfusion
and its
1.75
complications
Define HEM 1 Phy 12 Genesis and general * *
Inflammation PHYSIOLOGY characteristics of white blood cells
and the
1.5
mechanism HEM 1 Phy 13 Functions of WBC and * *
of monocyte macrophage cell system (
phagocytosis R.E.S).
PATHOLOGY HEM 1 Pth 9 Acute Inflammation 1

* *
102
HEM 1 Pth 10 Chronic Inflammation 1.5
* *
PATHOLOGY HEM 1 Pth 11 The role of leukocytes in 1
acute inflammation
* *
PHARMACOL HEM 1 Pha 4 Non Steroidal anti- 1.5
OGY inflammatory drugs. Classification,
* *
Recognize the Mechanisms and Pharmacology of
mechanism Aspirin.
of HEM 1 Pth 12 morphology of acute 1.75
inflammatory
PATHOLOGY inflammation
* * *
process and
HEM 1 Pth 13 Mediators of 1
host
Inflammation
* *
responses to
inflammation PHARMACOL HEM 1 Pha 5 Basic Pharmacology of 1
OGY Eicosanoid (Prostaglandin,
* *
Thromboxane, Leukotrienes) &
Vasoactive peptides
PATHOLOGY HEM 1 Pth 13 Morphology of chronic 1.75
inflammation (granuloma)
* * *
HEM 1 SUG 1 Acute inflammatory 1
SURGERY
codition(cellulitis, abcesses and others)
* *
INTEGRATED HEM 1 Cbl 3 Cellulitis & abcess 1.75
LEARNING (CBL)
Lectures
* * *
Demo:
Tutorials
Practical
/CBL/SBL
Self Study
Library
Digital
BCQs, SEQs
Skills Lab
EMQS
ATP
viva
SUBJECT
HEM 1 Pth 14 Extracellular 1.5

matrix and healing by
* a
*
connective tissue deposition
Describe the
mechanism of PATHOLOGY
HEM 1 Pth 15 The growth 1
tissue
factors and cytokines
* *
regeneration
& repair HEM 1 Pth 16 Local and 1
systemic factors affecting
* *
tissue renewal
HEM 1 Pha 6 Antimicrobials
(Overview of antibacterial
1.5 * *
drugs, classification and
drug resistance)
HEM 1 Pha 7 Cell wall 2
Overview the
synthesis inhibitors
* *
Antimicrobials (Penicilline) - I
PHARMACOLOGY
& their HEM 1 Pha 8 Cell wall 1.75
pharmacokine synthesis inhibitors * *
tics {cephalosporins and others} - II
HEM 1 Pha 9 Protein synthesis 1

inhibitors.
* *
HEM 1 Pha 10 Anti- 1
metabolites /nucleic acid * *
synthesis inhibitors.
103
HEM 1 Anh 2 Introduction 1.5
To Lymphoid Tissue And
* * *
ANATOMY
Immune System,
Histology Of Lymph Node
&Thymus
HEM 1 Phy 14 Types And 1
PHYSIOLOGY
Functions Of Lymphocytes
* *
HEM 1 Bio 10 1
BIOCHEMISTRY Immunoglobulin
* *
Differentiate HEM 1 Anh 3 Histology Of 1.75
the Lymph Node &Thymus
* * *
mechanism of
cellular and HEM 1 Anh 4 Histology Of 1
humoral ANATOMY
Spleen And Tonsils
* * *
immunity,
hypersensitivit
HEM 1 Anh 5 Histology Of 1.75
y and
Spleen And Tonsils
* * *
immunological
disorders
HEM 1 Mic 1 Innate And 1
Acquired Immunity And Its
* *
Significance Of Infectious
Diseases
MICROBIOLOGY
HEM 1 Mic 2 Antibody 1
Mediated Immune Response
* *
HEM 1 Mic 3 Cell Mediated 1

Immunity
* *
PHYSIOLOGY HEM 1 Phy 15 Cellular & 1.75
humoral immunity
* *
Lectures
Demo:
Tutorials
Practical
CBL/SBL
Self Study
Library
Digital
BCQs, SEQs
Lab
EMQS
Skills
ATP
viva
PHYSIOLOGY HEM 1 Phy 16 Allergy & 1

HYPERSENSITIVITY
* *
HEM 1 Pth 17 1
Enumerate the
Hypersensitivity reaction 1
* *
consequences PATHOLOGY
+2
and patho- HEM 1 Pth 18 1
physiology of Hypersensitivity reaction
* *
allergic and 3+4
immune MICROBIOLOGY HEM 1 Mic 4 Complement 1
responses. system & its role in
* *
immunity
PHARMACOLOGY HEM1 Pha 11 Histamine / 1
Antihistamine & ergot
* *
alkaloids
104
Describe MICROBIOLOGY HEM 1 Mic 5 Antigen 1.5
Antigen antibody reaction
* *
Antibody
reactions
Characterize the MICROBIOLOGY HEM 1 Mic 6 MHC & 1.5

significance of transplant
* *
MHC molecules.
PATHOLOGY HEM 1 Pth 19 Autoimmune 1.75

disease: mechanism
PHARMACOLOGY HEM 1 Pha 12 1
Immunomodulants &
* *
immunosuppressents
Discuss briefly MICROBIOLOGY HEM 1 Mic 7 1.5

immunodeficien Immunodeficiency states
* * *
cy states
PATHOLOGY HEM 1 Pth 20 General
features of autoimmune
* * *
disease
BIOCHEMISTRY HEM 1 Bio 11 Biochemical 1.75
interpretation of immune
* *
deficient disorder
PATHOLOGY HEM 1 Pth 21 1.75
Interpretation of
* *
autoimmune serology
Define PATHOLOGY HEM 1 Pth 22 Introduction 1
neoplasia its to Neoplasia:
* *
nomenclature, Nemenclature of tumors +
classification & terminologies
HEM 1 Pth 23 Classification 1
epidemiology.Di
of tumors, difference
* * *
fference between benign and
between benign malignant tumors
& malignant HEM 1 Pth 24 Characteristic 1
tumors. features of tumors and
* *
Epidemiology of cancers
PATHOLOGY HEM 1 Pth 25 Molecular 1

Basis of Cancer
* *
The HEM 1 Pth 26 Carcinogenic 1
pathogenesis of Agents and Their Cellular
* *
tumors , InteractionS
PHARMACOLOGY HEM 1 Pha 13 Cancer
carcinogenic Chemotherapy:
* *
agents & cancer (OVERVIEW)
chemotherapy
INTEGRATED HEM 1 Cbl 5 Lymphoma
LEARNING (CBL)
* *
Enumerate PATHOLOGY HEM 1 Pth 27 Host Defense
hematologic against TumorsTumor
* *
malignancy & Immunity
HEM1 Pth 28 Hematologic
host tumor malignancy: acute and
* *
immunity Community chronic
HEM 1 Com1 Normal
Recognize the
distribution curve
* *
105
importance of medicine HEM 1 Com 2 Dynamics of
Community disease transmission
* *
medicine in
HEM 1 Com 3 outbreak
disease
transmission & investigation
* *
HEM 1 Com 4 measure of
investigation
central tendency and
* *
dispersion
Importance of HEM 1 Mic 8 Structure of 1.75
microbiology in bacteria
* * *
recognition of HEM 1 Mic 9 Classification 1.75
disease caused and Growth of bacteria
* *
by bacteria
HEM 1 Mic 10 grams 1.75
,diagnosis in lab
staining
* * *
HEM 1 Mic 11 Normal flora 1.5
* *
HEM 1 Mic 12 Pathogenesis 1
of protozoal pathogenesis
* *
MICROBIOLOGY and micro organism
HEM 1 Mic 13 Malaria 1
* * *
HEM 1 Mic 14 Culture of 1.75
bacteria
* * *
HEM 1 Mic 15 Sterilization 1
and Disinfection
* *
HEM1 Mic 16 Acid fast 1.75
staining
* * *
HEM 1 Beh 1 Child 1
Development
* *
Recognize the HEM 1 Beh 2 puberty 1
importance of
BEHAVIORAL
adolescent
* *
SCIENCES
behavioral
HEM 1 Beh 3 Learning and 1
sciences
behaviour changes
* *
regarding
human
development HEM 1 Beh 4 Metacognition 1
and behaviour for web
* *
Recognize the HEM 1 Res 1 Sample 1.5
importance of techniques
*
RESEARCH
research METHODOLOGY HEM 1 Res 2 Principles of 1.5
methodology
data analysis
*
for conducting
research work
in later year
106
HEMATOLOGY MODULE
Time Table
Week1
Days 8:30- 9:30 9:30-10:30 11.00:-12:30 1:30-3:00
PHYSIOLOGY: BIOCHEMISTRY ANATOMY:

Introduction to the : Embryological development
Module Composition of of blood elements.
DAY 1 Composition of blood: plasma SELF STUDY
Hematogenesis
Blood: Cellular Components and NAME OF FACULTY
Components Proteins VENUE
NAME OF FACULTY NAME OF FACULTY
VENUE VENUE
Practical:GP A=Physiology:
peripheral Blood NAME OF
FACULTY
GP B=HISTOLOGY:
VENUE
BIOCHEMISTRY: Histologyof Blood NAME OF
Synthesis, Structure and FACULTY PHYSIOLOGY:
SELF VENUE
functions of Hemoglobin GP C =Self study Maturation of RBCs, Regulation
STUDY
DAY 2 ,oxygen dissociation of erythropoiesis
curve GP D1=Skills I/M and VENE NAME OF FACULTY
10:00-10:30 Puncture VENUE
NAME OF FACULTY
VENUE D2=SELF STUDY
GP E = PATHOLOGY LAB:
Bone marrow Changes with
ages and disease (Hemopoisis,
Aplastic Anemia) NAME OF
FACULTY
VENUE 1. B BEHAVORIAL SCIENCES
BIOCHEMISTRY SELF
Iron Metabolism STUDY 2. C=
DAY 3
NAME OF FACULTY 3. D Child Development
VENUE 10:00-10:30 4. A
5. E NAME OF FACULTY
VENUE
BIOCHEMISTR PHYSIOLOGY: BIOCHEMISTRY:
1. C
Y: classification of Abnormalities of Hb synthesis,
2. D= E
DAY 4 Vit.B12 / Folic anemia and porphyria ad its diffferent types
3. A
Acid/ B6 significance of red Variants of hemoglobin
NAME OF 4. B NAME OF FACULTY
cell indices
FACULTY NAME OF FACULTY VENUE
VENUE VENUE
PATHOLOGY- SELF 1. D
Anaemia of diminished STUDY 2. E=
DAY 5 erythropoiesis 3. A
(megaloblastic/iron 10:00-10:30 4. B
defanaemia,aplasticanaemi 5. C
a)
NAME OF FACULTY
PHYSIOLOGY PHARMACOLOG 1. E
HemolysisVENUE
and Y: 2. A=
DAY 6 hemolytic Agents used in 3. B SELF STUDY
NAME OF Anemias: 4. C
FACULTY
Hematopoietic , 5. D
VENUE Growth factors
NAME OF FACULTY
VENUE
107
HEMATOLOGY MODULE SEMESTER 1, Time Table: Week 2
HEMOGLOBINOPATHIES & HEMOSTASIS
Days 8:30- 9:30 9:30-10:30 11:00 -12:30 1.30-3.00

PATHOLOGY:
Hemolytic PHYSIOLOGY CLINICAL FACULTY
anaemia(hereditary BLOOD GOUPS History and clinical findings in an
spherocytosis,G6PD ABO/Rh system anemic patient SELF STUDY
DAY 1 NAME OF FACULTY
def,Sickle cell NAME OF FACULTY
disease) VENUE VENUE
NAME OF FACULTY
VENUE
GP=A= BIOCHEMISTRY
Hemoglobin electrophoresis
NAME OF FACULTY
VENUE
GP=B= MICROBIOLOGY
Practical Grams Staining
NAME OF FACULTY
BIOCHEMISTRY: CM
VENUE
Hemoglobinopathies and 10:00-10:30
DAY 2 GP= C= PHYSIOLOGY: PRIMARY HEALTH CARE
Thalassemia SELF
NAME OF FACULTY STUDY Blood grouping and cross NAME OF FACULTY
VENUE matching/ErythroblastosisFetalis VENUE
NAME OF FACULTY
VENUE
GP D2,=Skills I/M injections and
VenePuncture
D1= Self Study
GP E= CBL
BIOCHEMISTRY:
PATHOLOGY: Heme Degradation 1-B= 2-C
Thalassemia and related disorders 3-D
DAY 3 syndrome and 4-E SELF STUDY
NAME OF FACULTY hyperbilirubinemia
VENUE NAME OF FACULTY 5-A
VENUE
PHYSIOLOGY MICROBIOLOGY PHYSIOLOGY
1-C= 2-D
Hemostasis and Role Classification and Clotting cascade and
Growth of bacteria 3-E
of thrombocytes bleeding disorders
DAY 4 NAME OF FACULTY NAME OF FACULTY 4-A
NAME OF FACULTY
VENUE 5-B
VENUE VENUE
BIOCHEMISTRY PHYSIOLOGY: 1-D=

Vitamin K and its Fibrinolytic 2-E
DAY 5 disorders mechanism 3-A
NAME OF FACULTY NAME OF FACULTY 4-B
VENUE VENUE 5-C
PATHOLOGY: BEHAVORIAL SCIENCES
PHARMACOLOGY 1-E=
Heamorrhagic and Coagulants 2-A
thromboembolic Puberty Adolescent
DAY 6 &Anticoagulants 3-B
conditions
NAME OF FACULTY
NAME OF FACULTY 4-C NAME OF FACULTY
VENUE 5-D
VENUE VENUE
108
HEMATOLOGY MODULE SEMESTER I
Time Table: Week 3, WBC, INFLAMMATION
Days 8:30- 9:30 9:30-10:30 11:00 -12:30 1.30-3.00

PATHOLOGY
Bleeding diathesis MICROBIOLOGY MICROBIOLOGY
DA secondary to Normal flora Sterilization and Disinfection
NAME OF FACULTY SELF STUDY
Y1 platelet disorders NAME OF FACULTY
NAME OF FACULTY VENUE VENUE
VENUE
1- SELF STUDY
2. CBL hemoglobinopathies
GP: B=
3. Gp: C1skill lab
I/Vcannulation COMMUNITY
PATHOLOGY
SELF C2= SELF STUDY MEDICINE
Clotting factors related diseases 4. MICROBIOLOGY
DA + factor VIII,IX Deficiency STUDY Dynamics of Disease
Practical An account of culture
Y2 diseases and sensitivity set up in Lab. Trans;mission
10:00-10:30
Culture of bacteria Gp: D =
NAME OF FACULTY
VENUE
VENUE
VENUE
5. PHYSIOLOGY Practical:
Bleeding time & clotting time Gp:
E=
NAME OF FACULTY
PHARMACOLOG VENUE
Y MICROBIOLOGY 1-B
Thrombolytics / Pathogenesis of 2-C
SELF STUDY
DA Fibrinolytics+ microorganisms 3-D
Y3 antiplatelet drugs NAME OF FACULTY 4-E
NAME OF FACULTY VENUE 5-A
VENUE
PHYSIOLOGY 1-C CLINICAL
Genesis and general SELF 2-D FACULTY
DA characteristics of white blood STUDY History, Examination
10:00- 3-E
Y4 cells and Management of
10:30 4-A
NAME OF FACULTY a patient with
5-B
VENUE bleeding Disorder
PHYSIOLOGY 1-D NAME OF FACULTY
SELF
DA Functions of WBC and STUDY
2-E VENUE
Y5 monocyte macrophage cell 10:00- 3-A
system ( R.E.S). 10:30 4-B
DR. ANWARNLH-1 5-C
PATHOLOGY PATHOLOGY 1-E
DA Acute The role of leukocytes 2-A
Inflammation in acute inflammation 3-B SELF STUDY
Y6
NAME OF FACULTY NAME OF FACULTY 4-C
VENUE VENUE 5-D
109
HEMATOLOGY MODULE SEMESTER I TIME TABLE: WEEK 4
TISSUE RENEWAL, REGENERATION, AND REPAIR+ ANTIMICROBIALS
Day 8:30- 9:30 9:30-10:30 11:00 -12:30 1.30-3.00

s
PHARMACOLO GP: ASELF STUDY
GY CBL GP: B BEHAVORIAL SCIENCES
PATHOLOGY Basic Pharmacology
Mediators of SKILL LAB : I/Vcannulation
of Eicosanoid
DA Inflammation SKILL LAB GP: C2 Learning And Behaviour
(Prostaglandin,
Y1 NAME OF Thromboxane,
HISTO PATHOLOGY Morphology Of Change
FACULTY Acute Inflammation Gp: NAME OF NAME OF FACULTY
Leukotrienes) & FACULTY
VENUE VENUE
Vasoactive peptides VENUE
NAME OF
PHYSIOC2:SELF
PRACT/STUDY
TUTORIAL =
FACULTY DLC
VENUE GP: E
PHARMACOLO
GY
Non Steroidal
PATHOLOGY anti-inflammatory 1. B
Chronic drugs. 2. C
PATHOLOGY
DA Inflammation Classification, The Cell Cycle
3. D2
Y2 NAME OF Mechanisms and 4. E NAME OF FACULTY
FACULTY
5. A VENUE
VENUE Pharmacology of
Aspirin.
NAME OF
FACULTY
VENUE
Clinical faculty 1. C
Acute inflammatory 2. D
SELF
DA codition(cellulitis, abcesses 3. E2
STUDY
4. A
SELF STUDY
Y3 and others
10:00-10:30
NAME OF FACULTY 5. B
VENUE
PATHOLOGY 1. D
Extracellular matrix and COMMUNITY MEDICINE
SELF 2. E
DA healing by connective Outbreaks investigations
STUDY 3. A2
Y4 tissue deposition
10:00-10:30 4. B NAME OF FACULTY
NAME OF FACULTY VENUE
VENUE 5. C
PHARMACOLOGY
SELF
Antimicrobials PATHOLOGY
STUDY
DA (Overview of The growth factors and cytokines
Y5 antibacterial drugs, NAME OF FACULTY
10:00-10:30 VENUE
classification and drug
resistance.)
NAME OF FACULTY
VENUE
PATHOLOGY SELF 1. E
Local and systemic factors 2. A
DA STUDY
SELF STUDY
affecting tissue renewal 3. B2
Y6 NAME OF FACULTY 4. C
VENUE 10:00-10:30 5. D
110
HEMATOLOGY MODULE SEMESTER - I
TIME TABLE: WEEK 5th, IMMUNITY
Days 8:30- 9:30 9:30-10:30 11:00 -12:30 1.30-3.00

1-SELF STUDY = A
2-CBL =B
10.:00
PHARMACOLOGY
TO 3-SELF STUDY=C
DA Cell wall synthesis 10:30 4-Micropractical: Micro
inhibitors (Penicilline) - I pract: Acid fast staining NAME SELF STUDY
Y1
NAME OF FACULTY OF FACULTY
SELF 5-, HISTOPATHOLOGY
VENUE STUDY
VENUE
morphology of chronic
inflammation (granuloma)
NAME OF FACULTY
VENUE GP: E, DR. FAIZ
PHARMACOLOGY 10.:00 1. B PHYSIOLOGY
Cell wall synthesis TO 2. C Types And Functions Of
DA inhibitors2 {cephalosporins 10:30 3. D Lymphocytes
Y2 and others} NAME OF FACULTY
NAME OF FACULTY 4. E
SELF
VENUE 5. A VENUE
STUDY
ANATOMY
Introduction To 10.:00 1. C
Lymphoid Tissue And TO 2. D
DA Immune System, 10:30
Y3
3. E SELF STUDY
Histology Of Lymph
4. A
Node &Thymus SELF
NAME OF FACULTY STUDY 5. B
VENUE
ANATOMY
10.:00 1. D
Histology Of Spleen And
TO 2. E BIOCHEMISTRY
DA 10:30 Immunoglobulin
Y4 Tonsils. 3. A
NAME OF FACULTY
NAME OF FACULTY 4. B VENUE
VENUE SELF
STUDY 5. C
PHARMACOLO COMMUNITY MEDICINE
DA GY Measures Of Central Tendency
Protein synthesis SELF STUDY And Dispersion
Y5
inhibitors. NAME OF FACULTY
NAME OF VENUE
FACULTY
VENUE PHARMACOLO
MICROBIOLOG GY
Y
Overiew of
Anti-metabolites 1. E
/nucleic acid 2. A
DA protozoal synthesis inhibitors
Y6
pathogenesis and NAME OF 3. B SELF STUDY
classification FACULTY 4. C
NAME OF VENUE
FACULTY 5. D
VENUE
111
HEMATOLOGY MODULE SEMESTER I,
TIME TABLE: WEEK 6th
DAY 8:30- 9:30 9:30-10:30 11:00 -12:30 1.30-3.00

S
1-Histology PRACTICAL: lymph
node &thymus A = NAME OF
MICROBIOLOGY SELF FACULTY
2- SELF STUDY= B
Malaria STUDY VENUE
DAY NAME OF FACULTY 3-SKILL LAB =C1 SELF STUDY
1 VENUE 10:00-10:30 SELF STUDY=C2
4- 4-Micro practical Diagnostic
test based on serology=D, = NAME
OF FACULTY
5- SELF STUDY=E
VENUE
MICROBIOLOGY
PHYSIOLOGY MICROBIOLOGY
Innate And 1. B=
Allergy And Antibody Mediated
Acquired Immunity 2. C
DAY Hypersensitivity Immune Response
And Its 3. D
2 NAME OF
Significance in 4. E
NAME OF FACULTY FACULTY
Infectious Diseases 5. A
VENUE BEHAVORIAL
MICROBIOLOGY 1. C=
MICROBIOLOGY SCIENCES
Complement System 2. D
Cell Mediated
DAY And Its Role In 3. E
3 Immunity Metacognition For
NAME OF FACULTY Immunity NAME OF
FACULTY
4. A Web
VENUE
VENUE 5. B
NAME OF
PATHOLOGY
MICROBIOLOGY PATHOLOGY 1. D= FACULTY
Hypersensitivity
DAY Antigen Antibody Hypersensitivity 2. E VENUE
Reactions Type 3+4
Reactions Reactions Type 1+2 3. A
4 NAME OF
NAME OF FACULTY NAME OF FACULTY 4. B
VENUE VENUE FACULTY
5. C
VENUE
PHARMACOLOG Y 1. E=
MICROBIOLOGY
Histamine/Antihista
DAY
Immunodeficiency 2. A
mine & Ergot 3. B
5 Alkaloids states
NAME OF FACULTY
NAME OF FACULTY 4. C
VENUE 5. D
VENUE
PATHOLOGY PHARMACOLOG PATHOLOGY
Autoimmune Y General features of
DAY diseases: Immunomodulants Autoimmune diseases +
and SELF STUDY
6 mechanism NAME Prototype -Systemic
OF FACULTY Immunosuppressen autoimmune disease (SLE)
VENUE ts NAME OF FACULTY
VENUE
112
TH
HEMATOLOGY MODULE SEMESTER I, TIME TABLE: WEEK 7
DAY
S
8:30- 9:30 9:30-10:30 11:00 - 12:30 1.30-3.00
1. A= BIOCHEMISTRY:
Biochemical Interpretation of
Immune-deficient disorder NAME
OF FACULTY
VENUE
2. B= PHYSIOLOGY SGD: Cellular
PATHOLOGY
Introduction to Neoplasia: SELF and humoral Immunity NAME OF
Nemenclature of tumors + STUDY FACULTY
DA VENUE
3. C= PATHOLOGY TUTORIAL:
Y1
terminologies SELF STUDY
10:00-
NAME OF FACULTY
10:30
interpretation of Autoimmune
VENUE serology
NAME OF FACULTY
4. D= HISTOLOGY PRACTICAL:
VENUE
spleen and tonsils NAME OF
FACULTY
VENUE
5. E= CBL
PHARMACOLOGY SELF 1. B= CM
DA STUDY 2. C Normal Distribution
Antiviral agents
Y2 NAME OF FACULTY 3. D Curve
10:00- 4. E NAME OF FACULTY
VENUE
5. A VENUE
10:30
PATHOLOGY SELF
Classification of tumors, STUDY 1. C
difference between 2. D
DA
Y3 benign and malignant 10:00- 3. E SELF STUDY
tumors 10:30 4. A
NAME OF FACULTY 5. B
VENUE
PATHOLOGY SELF
STUDY 1. D
Characteristic features of 2. E
CLINICAL
DA tumors and FACULTY
10:00- 3. A
Y4 Epidemiology of cancers Approach to patient
4. B
NAME OF FACULTY 10:30 with lymphadenopathy
5. C
VENUE
SELF
PHARMACOLOGY STUDY PATHOLOGY
DA Folate Antagonists Molecular Basis of Cancer
Y5 NAME OF FACULTY 10:00- NAME OF FACULTY
VENUE 10:30 VENUE
PATHOLOGY SELF 1. E
Carcinogenic Agents and STUDY 2. A
DA Their Cellular
Y6
3. B SELF STUDY
Interactions 10:00- 4. C
NAME OF FACULTY 10:30 5. D
VENUE
113
HEMATOLOGY MODULE, SEMESTERI,
TIME TABLE: WEEK 8TH
DAY 8:30- 9:30 9:30-10:30 11:00 -12:30 1.30-3.00

DAY 1 PATHOLOGY
Host Defense MICROBIOLOGY
against Tumors SELF STUDY SELF STUDY
MHC And Transplant
Tumor Immunity NAME OF FACULTY
NAME OF FACULTY
VENUE VENUE
DAY 2 (REVISIT)
(REVISIT) (REVISIT)
PHYSIOLOGY:
PATHOLOGY- BIOCHEMISTRY:
classification of
Anaemia of diminished Hemoglobinopathies and
SELF STUDY
anemia and Thalassemia
erythropoiesis
significance of red NAME OF FACULTY NAME OF FACULTY
cell indices VENUE VENUE
NAME OF FACULTY
DAY 3 VENUE
(REVISIT) (REVISIT)
(REVISIT)
PATHOLOGY: PHYSIOLOGY
BIOCHEMISTRY
Thalassemia Clotting cascade and SELF STUDY
Vitamin K and its disorders
syndrome bleeding disorders NAME OF FACULTY
NAME OF FACULTY NAME OF FACULTY VENUE
VENUE VENUE
DAY 4 (REVISIT)
PHARMACOLO
GY (REVISIT)
(REVISIT)
Antimicrobials PHYSIOLOGY
PHYSIOLOGY:
(Overview of Allergy And SELF STUDY
antibacterial drugs, Fibrinolytic mechanism
NAME OF FACULTY Hypersensitivity
classification and VENUE NAME OF FACULTY
drug resistance.) VENUE
NAME OF FACULTY
VENUE
DAY 5 PATHOLOGY (REVISIT) (REVISIT)
Haematologic PHARMACOLOGY MICROBIOLOGY
malignancy: acute Cell wall synthesis Complement System And Its
and chronic inhibitors (Penicilline) I Role In Immunity
NAME OF FACULTY NAME OF FACULTY NAME OF FACULTY
VENUE VENUE VENUE
DAY 6 (REVISIT) (REVISIT)
PHARMACOLOG (REVISIT) PATHOLOGY
Y MICROBIOLOGY Classification of tumors,
Cell wall synthesis Malaria difference between SELF STUDY
inhibitors2 NAME OF FACULTY
{cephalosporins and VENUE benign and malignant
others} tumors
SUNDA VENUE VENUE
Y
DAY 1
SELF STUDY
DAY 2
MODULE EXAMINATION
114
LEARNING OBJECTIVES OF LECTURES
EMBRYOLOGY
2. EMBRYOLOGICAL DEVELOPMENT OF BLOOD ELEMENTS.

HEM 1 Ane1 Ane1
HEMATOGENESIS
Define hematopoiesis.
Ideentify and Descibe the sites and source of heamopoiesis before and after
birth
Differentiate stem / pluripotentd cells, progenitor and precursor (blasts) cells
Explain the development of various types of blood cells
HISTOLOGY
3. INTRODUCTION TO LYMPHOID TISSUE AND IMMUNE SYSTEM AND

HEM 1 Anh 2
HISTOLOGY OF LYMPH NODE AND THYMUS
Understand the immune system and lymphoid tissue.

Differentiate between central lymphoid organs and peripheral lymphoid
organs.
Identify the structure and function of lymph nodes.
Identify the structure, function and histological appearance of thymus.
4. HEM 1 Anh 4 HISTOLOGY OF TONSIL AND SPLEEN
Define locations of tonsils.

Describe histological features of tonsils.
Enlist functions of tonsils.
Enlist histological features of spleen.
Enumerate Functions of spleen.
115
PHYSIOLOGY
1. HEM 1 Phy 1 COMPOSITION OF BLOOD:CELLULAR COMPONENTS
Composition of blood
Functions of blood.
Plasma and its composition.
R.B.Cs: Their structure, function and count.
W.B.Cs: Their types, structure, function and count.
Platelets: Their structure, function and count.
2. HEM 1 Phy 2 MATURATION OF RBCS. REGULATION OF ERYTHROPOIESIS
The end of lecture student should be able to know,

What is haemopoiesis.
Types of stem cells.
Classification of stem cells.
Sited of haemopoisis.
Regulation of haemopoeitic cells.
Interactions.
3. HEM 1 Phy 4 CLASSIFICATION OF ANEMIA & SIGNIFICANCE OF RED CELL INDICES

Define anemia?
Explain classification of anemia
Morphological classification
Pathophysiological classification
Functional classification
Describe diagnoses of anemia by red cell indices
4. HEM 1 Phy 5 HEMOLYSIS AND HEMOLYTIC ANEMIA
Define hemolysis?
Describe menbrane defects.
Define
o Hereditory spherocytosis.
o Sickle cell anemiia,
o Thalesemia.
o Autoimmune hemolytic anemia.
116
5. HEM 1 Phy 6 HEMOSTASIS & ROLE OF THROMBOCYTES
Define Hemostasis.
Delineate the process of hemostasis that restricts blood loss when
vessels are damaged.
Give a picture of the structure of platelets.
Describe the Role of platelets in hemostasis.
Give the Abnormalities of Hemostasis
6. HEM 1 Phy 7 CLOTTING CASCADE AND BLEEDING DISORDERS
Describe intrinsic pathway of clotting

Describe extrinsic pathway of clotting
Enlist clotting factors
Enumerate clinical conditions due to deficiency of clotting factors.
Define von Willebrand disease (VWD)
Define hemophilia
7. HEM 1 Phy 8 FIBRINOLYTIC MECHANISM
Define fibrinolysis
Describe mechanism of fibrinolytic mechanism
Describe the therapeutic role of fibrinolytic mechanism
Enumerate few disorders related with abnormal fibrinolytic
pathway
8. HEM 1 Phy 14 TYPES AND FUNCTIONS OF LYMPHOCYTES
Enlist types of lymphocytes

Describe specificity of antibodies & sensitized t- cells.
Describe clones of lymphocytes.
Explain activation of t lymphocytes by helper t- cells
Describe formation of antibodies.
Enlist differences b/t primary & secondary response.
Describe mechanism of action of antibodies.
Explain types & formation of t-cells.
117
9. HEM 1 Phy 10 ABO AND RH SYSTEM (Blood Grouping)/ ERYTHROBLASTOSIS
FETALIS
Describe function of agglutinogen and agglutinin in relation to

blood group
Describe antigen and antibody of ABO system
Describe mechanism that inherit the ABO system.
List phenotype and genotype of possible ABO types.
Describe antigen and antibody of Rh system.
Explain universal donor and universal recipient .
Describe transfusion reaction related to ABO and Rh system
Describe erythroblastosis foetalis
10.HEM 1 Phy 12 GENESIS AND GENERAL CHARACTERISTICS OF WHITE BLOOD CELLS
Describe about different types of white blood cells.

Describe the genesis of white blood cells.
Know the general characteristics of white blood cells.
11. HEM 1 Phy 13 FUNCTIONS OF WHITE BLOOD CELLS MONOCOTS-MACROPHAGE

SYSTEM (RETICULOENDOTHELIAL SYSTEM)
Describe the functions of Leucocytes.

Define the hallmark of acute inflammation.
Explain the role of neutrophils, eosinophils, basophils, monocytes
and macrophages in the immune system.
Describe the components of the monocyte macrophage system
10. HEM 1 Phy 16 ALLERGY AND HYPERSENSITIVITY
Describe Hypersensitivity reaction.

Define the term Allergen.
Classify the hypersensitivity reactions
List the diseases associated with hypersensitivity reactions
Describe the mechanisms of damage in hypersensitivity
reactions.
118
BIOCHEMISTRY
1. HEM 1 Bio 1 COMPOSITION OF BLOOD: PLASMA COMPONENTS AND PROTEINS
Discuss the components of plasma.

Discuss about of plasma proteins.
Explain the role of plasma proteins in human body.
List the diseases in which plasma proteins are raised or decreased
2. HEM 1 Bio 2 STRUCTURE,FUNCTIONS, PROPERTIES & OXYGEN- DISSOCIATION CURVE

OF HEMOGLOBIN
The synthesis of hemoglobin
The structural details of hemoglobin molecule specially its quaternary
structure
The T and R forms of Hemoglobin
The oxygenation of hemoglobin molecule
The Hemoglobin oxygen dissociation curve and factors affecting it
The Bohrs effect
Compare the hemoglobin and myoglobin molecule with respect to
structure and function
1. HEM 1 Bio 3 IRON METABOLISM
Know the biochemical properties of iron.

Enlist the functions of iron in body .
State the sources of iron in diet.
Describe the steps of iron aBehorption from gut to cells.
Describe its forms of storage in the body.
Know the clinical importance of iron regulation in body.
2. HEM 1 Bio 4 VIT.B12/ FOLIC ACID/ B6
Describe the sources, RDA and Chemical nature of Vitamin B12, Folic Acid
& Vitamin B6 .
Explain the aBehorption of B12, Folic acid & Pyridoxine.
Discuss the metabolism of B12, folic acid & B6.
Describe the deficiency states of B12, folic acid & B6.
119
3. HEM 1 Bio 5 ABNORMALITIES OF HEMOGLOBIN SYNTHESIS, PORPHYRIA & ITS
DIFFERENT TYPES VARIANTS OF HB
Define Hemoglobin structure
Describe the R and T state of the hemoglobin
Explain the Heme structure and its synthesis
Enlist defects of heme synthesis
Describe major forms of porphyrias
Explain variants of Hemoglobin according to the chains
4. HEM 1 Bio 6 HEME DEGRADATION & RELATED DISORDERS & HYPERBILIRUBINEMIA
State the normal turnover of erythrocytes

List the sites of erythrocyte and hemoglobin degradation
Explain the working of heme oxygenase system
Relate the levels of bilirubin with the discoloration of tissues
Explain the excretion of bile pigments through the body
Relate various types of hyperbilirubinemia with altered heme and bilirubin
metabolic processes
5. HEM 1 Bio 7 HEMOGLOBINOPATHIES & THALASEMIA

Define hemoglobinopathies
Appreciate normal globin chain configuration
Define and classify thalassemias
Appreciate four possible alpha thalassemia syndromes
Explain type of mutations responsible for beta thalassemia
Lab test responsible for diagnosing hemoglobinopathy and thalassemias
6. HEM 1 Bio 9 VITAMIN K AND ITS DISORDERS

Describe structure of vitamin K
Explain sources and functions of vitamin K
Enlist clinical manifestations of deficiency of vitamin K
Describe vitamin K role in gamma carboxylation reactions
Enumerate conditions predisposing to Vitamin K deficiency
7. HEM 1 Bio 10 IMMUNOGLOBULIN
Define immunoglobulin (Ig)

Describe the structure of Ig
Classify different types of Ig
Give the important properties of each class of Ig
Justify the role of each class of Ig in diseased condition
120
PATHOLOGY
1. HEM 1 Pth 1 ANEMIAS OF DIMINISHED ERYTHROPOIESIS

(MEGALOBLASTIC/IRODEFICENCY,APLASTIC ANEMIA)
Define anaemia
List the factors that are important in regulating erythropoiesis
List the types of common anaemia
Discuss the pathogenesis of anaemia
Discuss the basis for hematological laboratory methods in anaemia
Interpret results of hematological tests in the diagnosis of anaemia
Describe the basis of Coombs Test
Name the types of anaemia due to nutritional deficiency
Discuss the pathogenesis of anaemia due to nutritional deficiency
2. HEM 1 Pth 2HEMOLYTIC ANEMIAS (HEREDITARY SPHEROCYTOSIS. G6PD DEFFICIENCY,

SICKLE CELL ANEMIA)
To define hemolytic anemia.

To explain types of hemolytic anemia.
To identify morphological features on peripheral blood.
To discuss pathogenesis involved in hemolytic anemia.
3. HEM 1 Pth 4 THALASSEMIA SYNDROME
To discuss Thalassemia Syndromes

To understand different types of mutations.
To explain pathogenesis of thalassemia syndromes.
To identify morphological features on peripheral blood smear.
4. HEM 1 Pth 5 HEMORRHAGIC & THROMBO-EMBOLIC CONDITIONS
Define causes of hemorrhagic disorders.

Enlist lab tests in diagnosis.
Discuss the mechanisms involved.
5. HEM 1 Pth 6 BLEEDING DIATHESIS SECONDARY TO PLATELETS DISORDERS

(DISORDERS OF PRIMARY HEMOSTASIS)
Define haemostasis
Study the different processes in haemostasis
Study the synthesis, cytoplasmic organization and functions of platelets
Describe the role of platelets in haemostasis
Describe the steps in blood coagulation
121
Describe the fibrinolytic system
Describe the physiological basis of tests for haemostatic function
List common Haemorhhagic disorders
Describe types of thrombocytopenia
Explain the effects of low platelet count on Hemostasis
6. HEM 1 Pth 7COAGULATION FACTORS VIII & IX DEFICIENCY
Describe etiology of hemophilia

Describe pathogenesis and pathophysiology of hemophilia
Explain classification of hemophilia
Diagnose hemophilia based on clinical features and laboratory findings
7. HEM 1 Pth 14 EXTRACELLULAR MATRIX AND HEALING BY CONNECTIVE TISSUE
Review the various components of ECM & its role in healing

Understand the basic features of repair
6. HEM 1 Pth 15 GROWTH FACTORS AND CYTOKINES
What is growth factor & cytokine.

Types of growth factors
Sources of growth factors
Function of growth factors
7. HEM 1 Pth 16 LOCAL & SYSTEMIC FACTORS AFFECTING TISSUE RENEWAL
List the systemic factors that affect wound healing.

List local factors that affect wound healing.
List potential complications of wound.
8. HEM 1 Pth 9 ACUTE INFLAMMATION

Describe about the acute inflammation.
Describe the changes occurring in acute inflammation.
9. HEM 1 Pth 10 CHRONIC INFLAMMATION
Describe the chronic inflammation.

Describe the chronic inflammatory cells and mediators.
Describe the systemic effects of chronic inflammation.
10. HEM 1 Pth 11 THE ROLE OF LEUKOCYTES IN ACUTE INFLAMMATION
Describe the categories of the various qualitative alterations of

leukocytes.
122
Describe procedures performed for the detection and diagnosis of
qualitative alterations of leukocytes.
Describe the disease states/ conditions seen in qualitative alterations
of leukocytes.
Describe the peripheral blood findings seen in qualitative alterations of
leukocytes.
Describe the categories of various quantitative alterations of
leukocytes.
Define relative and absolute values
List the major causes of quantitative alterations of leukocytes
11. HEM 1 Pth 13CHEMICAL MEDIATORS OF ACUTE INFLAMMATION
Know and describe the chemical mediators released during acute

inflammation.
12. HEM 1 Pth 17 mHYPERSENSITIVITY REACTION I & II
Define hypersensitivity
Enlist Types of hypersensitivity
Describe Pathogenesis of hypersensitivity
13. HEM 1 Pth 18 HYPERSENSITIVITY REACTIONS TYPE III AND IV
Define type III Hypersensitivity reactions

Describe different eg type III of hypersensitivity reactions
Define type IV hypersensitivity reactions
Describe different eg of type IV hypersensitivity reactions.
14. HEM 1 Pth 19 AUTOIMMUNE DISEASE:MECHANISM
Define Autoimmunity
Enlist the autoimmune diseases
Describe association between HLA and autoimmune disorders
Define Sjogrens syndrome
15. HEM 1 Pth 20 GENERAL FEATURES OF AUTOIMMUNE DISEASES
General features of autoimmune diseases.

Pathogenesis and clinical manifestations , of systemic
autoimmune disease (SLE).
16. HEM 1 Pth 22 NEOPLASIA AND NEOPLASIA NOMENCLATURE
Describe the definition of neoplasia.

Describe the nomenclature of neoplasia.
123
17. HEM 1 Pth 23 CLASSIFICATION OF TUMORS,DIFFERENCE BETWEEN BENIGN AND
MALIGNANT TUMORS
Classification of tumors.
Difference between benign and malignant tumors
18. HEM 1 Pth 24 CHARACTERISTIC FEATURES OF TUMOR & EPIDEMIOLOGY OF CANCERS
Growth phases of malignant cancer

Dysplasia and carcinoma-in-situ
Functional capabilities of benign and malignant tumours
Growth factors and rate and clinical implications
Local invasion of benign and malignant tumours
Pathways of spread, seeding, lymphatic and haematogenous
spread
Invasion of extracellular matrix
19. HEM 1 Pth 25 MOLECULAR BASIS OF CANCER
Normal cell cycles and fundamental principal of cancer regarding

cycle
Essential alterations in malignant transformation
Steps of cell proliferation
Protooncogenes and growth factors and their receptors
Two-hit hypothesis of knudson
Tumor supressor genes
Cellular changes in tumor cells
DNA repair defects
Homing of tumor cells
Development of sustained angiogenesis
HEM 1 Pth 26 CARCINOGENIC AGENTS AND THEIR CELLULAR INTERACTIONS
Different types of carcinogens

Mechanism of action of carcinogens
Therapeutic agents that also act as carcinogens
Skin cancer and radiation
Viral carcinogens and types
20. HEM 1 Pth 27 IMMUNITY TO TUMORS
Define immunity
Describe antigens associated to tumors
Explain mechanism of tumor immunity
Describe carcinoembryonic antigen & alpha fetoprotein
124
21. HEM 1 Pth 28 HEMATOLOGIC MALIGNANCY:ACUTE & CHRONIC
Understand Malignacies involving Bone marrow

Understand FAB Classification
Understand Diagnostic criteria for acute and chronic cases of
hematologic malignancies
Explain signs and symptoms of acute and chronic leukemias
MICROBIOLOGY AND BASIC BACTERIOLOGY

1. HEM 1 Mic 8 STRUCTURE OF BACTERIAL CELL
Describe the important components of a typical bacterial cell.

State the differentiating characteristics of gram positive and gram
negative bacteria and its importance in diagnosis and vaccination,
Enlist the specialized structure of bacterial cell and their role in
disease.
2. HEM 1 Mic 9 CLASSIFICATION & GROWTH OF BACTERIA
Identify bacteria and its properties

Classify bacteria according to its shape, arrangement, gram
staining, method of respiration.
Define the pattern of bacterial growth
Explain cycle of bacterial growth
Draw & label the bacterial growth curve
Describe aerobic & anaerobic growth
Explain the fermentation of sugar, its products & clinical
laboratory test
3. HEM 1 Mic 11 NORMAL FLORA

Define normal flora.
Describe colonization of normal flora.
Discuss the role of normal flora in health & disease
Explain harmful effects of normal flora

4. HEM 1 Mic 12 PATHOGENESIS OF MICRORGANISMS
Differentiate b/w true pathogens, opportunists and commensals

List the routes of transmission of infection
Describe colonization, pathogenesis, spread and excretion of
infectious agents.
125
5. HEM 1 Mic 13 MALARIA
Define Malaria and list the types of plasmodium species causing
malaria
Describe the pathogenesis with relevant lab tests
6. HEM 1 Mic 15 STERELIZATION & DISINFECTION
Define Sterelization and Disinfection.

Describe various methods used for sterelization and disinfection and
their application in hospitals,OTs,LaBeh.,and health related situations
7. HEM 1 Mic 1 INNATE AND ACQUIRED IMMUNITY & ITS SIGNIFICANCE OF INFECTIOUS
DISEASE
Define immunity,and differentiate b/w innate and acquired
immune response.
Describe various organs and cells involved in immunity.
8. HEM 1 Mic 2 ANTIBODY MEDIATED IMMUNE RESPONSES
Elist various types of antibodies.

Describe different functions of antibodies.
Describe different Mechanisms of antibody mediated immune
responses.
9. HEM 1 Mic 3 CELL MEDIATED IMMUNE RESPONSE
Define cell- mediated immune response

Enlist different types of T cells and their functions
Explain antigen processing and presentation
Discuss method of activation of Tcells
Discuss method of activation of macrophages and delayed type
hypersensitivity
Describe MHC, different classes, structure, expression and gene
defects.
10. HEM 1 Mic 4 COMPLEMENT & ITS ROLE IN DISEASE

Define complement system
Explain activation & regulation of complement system
Discuss biologic effects of complement system
Describe clinical aspect of complement system
126
11. HEM 1 Mic 5 ANTIGEN-ANTIBODY REACTIONS IN THE LABORATORY
Discuss significance of immunodiagnosis in disease.

Define specificity and sensitivity of a test.
Explain the basic principles of serological tests, and their
application in the diagnosis of various pathological conditions.
12. HEM 1 Mic 6 MAJOR HISTOCOMPATIBILITY COMPLEX (MHC) & TRANSPLANT
Define major histocompatibility complex

Describe its role in immunity and transplant reaction.
13. HEM 1 Mic 7 IMMUNODEFICIENCY STATES
Discuss Primary immunodeficiency and its causes

Discuss Secondary immunodeficiency and its causes
Explain transmission of HIV
Define epidemiology
HEM 1 Mic 7 IMMUNODEFICIENCY STATES
Discuss Primary immunodeficiency and its causes

Discuss Secondary immunodeficiency and its causes
Explain transmission of HIV
Define epidemiology
PHARMACOLOGY
HEM 1 Pha 1 Agents used in Anemias: Hematopoietic , Growth factors
Describe the causes of different anemias.

Explain the type of anemia expected as a result of deficiencies of
iron, erythropoietin, Vitamin B12 and folic acid.
Describe the primary sites of action of erythropoietin.
Explain the approved indications for treatment of anemia by
erythropoietin, iron, folic acid and Vitamin B12.
Describe the aBehorption of iron by the intestines.
Explain the treatment for iron toxicity or overdose
127
HEM 1 Pha 2 Coagulants & Anticoagulants
Describe how Blood Clots are formed.

Describe how the blood clots are broken down ?
Know what drugs can be used to regulate clotting ?
Explain how to rectify clotting deficiencies
HEM 1 Pha 3 THROMBOLYTIC/FIBRINOLYTIC+ANTI PLATELET
Describe the causes and treatment of atheroma and arterial

thrombosis.
List the drugs used for coronary thrombosis
Appreciate the dangers of platelet clumping and how drugs may
prevent this.
Understand the treatment and causes of patients with coronary
thrombosis.
classify and describe the pharmacology of Thrombolytics &
Fibrinolytics drugs
describe the pharmacodynamics and pharmacokinetics of
Thrombolytics & Fibrinolytics, including their side-effects.
HEM 1 Pha 4 NSAIDS (NON-STEROIDAL ANTI-INFLAMMATORY DRUGS)
Describe the mechanism of action of nsaids

Describe the common pharmacological effects of nsaids
Enlist the common adverse effects of nsaids
Describe the classification of nsaids
Explain common mechanism of action (cyclooxygenase inhibition)
Describe different selectivities to cox I and II
HEM 1 Pha 5 BASIC PHARMACOLOGY OF EICOSANIDE
Describe the type, mechanism of production and physiologyical

effects of :
Angiotensin II.
Vasopressin.
Endothelins .
Neuropeptide Y).
Bradykinin and related Kinins.
Natriuretic Pepties.
Vasoactive Intestinal Peptide.
Substance P.
128
HEM 1 Pha 6 ANTIMICROBIAL AGENT
Define antibiotics.
Describe ifferent antimicrobial agents.
Explain uses and reasons of Combination of antimicrobial drugs.
Define drug resistance.
Explain Complication of antibiotic therapy.
Explain Patient factors for choosing antimicrobial agent
HEM 1 Pha 7 CELL WALL SYNTHESIS INHIBITORS -1
Describe the structural relationship of the penicillin

molecule with antimicrobial activity.
Explain the mechanism of action of b-lactam
antibiotics.
Describe the pharmacokinetic properties of penicillins.
Discuss primary therapeutic indications for penicillin G.
Explain the major side effects of penicillins.
Describe the indications for broad-spectrum penicillins.
List the penicillinase-resistant penicillins.
List the combinations of inhibitors of b-lactamase with
penicillins.
HEM 1 Pha 8 CELL WALL SYNTHESIS INHIBITORS-2 CEPHALOSPORINS
Explain the mechanism of action of cephalosporins.

Describe the four generations of cephalosporins with specific
examples and the differences in their
Describe antimicrobial spectrum and pharmacokinetic
properties.
Describe the adverse effects due to cephalosporins.
Explain the terms superinfection and cross-
hypersensitivity.
Discuss the mechanism of action of vancomycin.
Describe the pharmacokinetic properties,
therapeutic indications and toxicities of vancomycin.
HEM 1 Pha 9 PROTEIN SYNTHESIS INHIBITORS

Explain the mechanism of action and the mode of bacterial
resistance of protein synthesis inhibitors.
Describe the therapeutic indications for each class of antibiotics.
List the various toxicities associated with each class of antibiotics.
Explain the drug interaction of tetracyclines and antacid
129
Describe the adverse effects of Tetracycline, Chloramphenicol &
Aminoglycosides, including contraindications in children
and pregnant women.
HEM 1 Pha 10 ANTI METABOLITES
Describe Folate antagonists and their classification
Discuss sulfonamides and trimethoprim and mechanism of action,
therapeutic use and resistance
Explain Co-trimoxazole and its therapeutic uses and adverse effects
Describe Quinolones and DNA gyrase inhibitors, types and
mechanism of action
HEM 1 Pha 11 Histamine and Antihistamine Agents
Explain how histamine is formed and describe the locations of its
synthesis, storage and catabolism.
Explain the difference between H1 and H2 receptors and their
physiologic/path-physiologic function .
Describe the "triple response of Lewis" and the mechanism(s)
underlying each response.
Describe the primary therapeutic uses, pharmacokinetic properties,
and side effects of H1 and H2 antagonists and the
antidegranulating drugs.
HEM 1 Pha 12 IMMUNOMODULANTS AND IMMUNOSUPPRESSENTS
Define the general principles of immunosuppression.
Name immunosuppressants and, for each, describe the mechanism
of action, clinical uses and toxicities.
Describe the mechanisms of action, clinical uses and toxicities of
antibodies used as immunosuppressants.
Describe the general principles of immunostimulants and their
indications.
Describe the different types of allergic reactions to drugs.
HEM 1 Pha 13 CANCER CHEMOTHERAPY
Explain the role of chemotherapy in the management of patients

with cancer.
Describe the prospects for "cure", or long term survival ,the various
limitations to effective drug treatment.
Define and explain the terms: selective toxicity, mass doubling time
and growth fraction.
Explain the concept of "total cell kill" in cancer patients.
Explain the term cell cycle specificity and be able to classify the
various anticancer agents based on this parameter.
Describe the principles of combination chemotherapy in the
treatment of cancer.
Explain the mechanisms for resistance to anticancer drugs.
Describe the mechanism of action and therapeutic indications of
various anticancer drugs.
Describe the common toxic effects for each major class of
anticancer drugs (alkylating agents, antimetabolites, natural
products and miscellaneous agents).
130
COMMUNITY MEDICINE
HEM 1 Com1 Normal distribution curve
Define epidemiology
Appreciate unique skills in epidemiology
Enlist two broad types of epidemiology
Differentiate between laboratory science and field science
Enlist Uses of epidemiology
HEM 1 Com2 DynamicsOf Disease Transmission

Define epidemiologic triode of disease transmission.
Enlist factors influencing disease transmission.
Describe models of disease transmission.
Know timeline for infection.
Explain iceberg concept of infection.
Define herd immunity
HEM 1 Com 3 OUTBREAK INVESTIGATION
Define outbreak
Describe Purpose of an outbreak investigation
Enumerate steps of an outbreak investigation
HEM 1 Com 4 MEASURE OF CENTRAL TENDENCY AND DISPERSION

Define biostatics.
Enlist uses of biostatics.
Appreciate role of biostatician.
Enlist and calculate measures of central tendency and dispersion.
BEHAVIORAL SCIENCES
Hem 1 Beh 1 Childdevelopment
Describe the child development
Discuss the achievement of basic milestones
Enumerate the ways of communication among children
Discuss the cognitive development
Hem 1 Beh 2 Puberty adolescent
Define puberty
Enlist the secondary sexual charaterstics
Discuss the sexual and social identity
Hem 1 Beh 3 Learning and behaviour change
Discuss meaning of 'learning'
Enlist different theories of learning
Describe difference between classical & operant conditioning
Explain conditioning in daily life and clinical setting
Enumerate concepts and principles of learning theories
131
Hem 1 Beh 4 Metacognition for web
Discuss importance of metacognition
Enlist the benefits of metacognition strategies
Enumerate factors influence metacognition
Describe dimensions of metacognition
Blood Module:
I. I/M Injection:
Introduction/ Rationale
It is one of the commonest ways of administering medications parenterally.
Learning Objectives
After the session the student should be able to :
Demonstrate and perform the procedure proficiently.
II. Venipuncture:
Introduction/ Rationale
Venipuncture is the process of obtaining intravenous access for the purpose of
intravenous therapy and obtaining a sample of venous blood. Because of its importance
and potential hazards for the pt. every doctor should be proficient in this basic
procedure.
Learning Objective
At the end of the session the student should be able to:
Enlist the equipment needed for the procedure.

Demonstrate the skill proficiently.
III. I/V Cannulation:
Introduction (Rationale):
This is one of the most important skills for giving parenteral medications and fluids to
patients.
Learning Objectives:
At the end of the session students should be able to:

Identify the correct sites for I/V cannulation
Demonstrate correct method of I/V Cannulation
132
RESEARCH METHODOLOGY
Hem 1 Res 1 Sample
techniques
Describe different types of sample
Explain random sampling
Correlate differences between probability and nonprobability
CASE BASED LEARNING

1. CBL 1
Correlate the changes in structure and function of the different types of

Hemoglobin in health and in disease states.
Correlate different Hb electrophoresis pattern
Relate normal and abnormal haemostatic mechanisms with the coagulation
cascade
Relate blood and blood components transfusion and transfusional reactions
2. CBL 2
Learn the clinical approach to bleeding disorders, specifically platelets disorders

versus coagulation disorders
Discuss and differentiate between extrinsic and intrinsic pathways
3. CBL 3
Interpret the report of Complete Blood Count.

Identify abnormalities in a Complete Blood Count.
Describe different types and causes of anemia.
Understand Iron deficiency anemia.
4. CBL 4
Define Lymphadenopathy
Identify different causes of lymphadenopathy
Describe the mechanism of lymphadenopathy
Explain different types of lymphnodes
5. CBL 5
Describe different types of hyper-sensitivity reactions

List the examples of different hyper sensitivity reactions
Understand the mechanism of anaphylaxis
133
WEEK 1st 2nd 3rd 4th 5th 6th Round of %
TOTAL *** for PAPER II
GEN - - - - - - -
ANAT. -
EMBR 1.75 - - - - - 1.75 1.22 1
HISTO 1.50 - - - 4 1.75 7.25 5.08 6
PHYSIO 7 6.25 5 1.75 2 1.75 16.66 17

23.75
BIOCH 9.25 2.75 - - 1 1.75 10.35 11

EM 14.75
PHARM 1 2.50 6 1.75 1 1 9.29 10
13.25
PATHO 4.50 4 7.25 5.25 2 9.75

32.75 22.98 23
MICRO 3.25 7 2.75 2.75 7 - 22.75 15.96 16
COM.M 2.50 1.50 1 1 - 1.50 5.26 6

ED
7.50
BEH.SC 1 - 1.50 1 - 1 3.15 3

I 4.50
RES.ME 1.50 1.75 - - - - 2.28 2

TH
3.25
SKILLS 1.50 - 1.75 1.75 1.50 - 6.50 4.56 -
CLINIC 2 1.50 - 1 - - 3.15 5

AL 4.50
FACUL
TOTAL
TY 36.75 29 27 18 20 20.25 142.5 99.94 100
1
TOTAL 1.75 1.75 1.75 1.50 1.75 8.50 - -
2
134
HEMATOLOGY MODULE
(SEMESTER 1)
SUMMATIVE ASSESMENT
THEORY

SEMESTER EXAM
ATP 25
PAPER-II
20
based on CBL
Total 100
MODULE EXAM
EMQs 10
ATP 20
MODULE PAPER 20%
One best Questions
20
based on CBL
Total 100
STRUCTURED VIVA

ASSESMENT
SUMMATIVE
SEMESTER
EXAM
See Semester
PAPER-III B Structured viva
Assessment Plan
ASSESMENT TOOLS
Structured Feedback
ASSESMENT DURING CBL SESSION Given to the Student by
Facilitator
NOTE: Paper I & III A of Semester 1 Examination are Based on Foundation Module.
135
CREDIT HOURS
SEMESTER I
HEMATOLOGY MODULE
II 6
Hem 1
III B 3
136
ASSESMENT PLAN, SEMESTER-1
CREDIT
PAPER CONTENT WEIGHTAGE
HOURS
Foundation Module
80 Marks
(Semester Theory)
100
I Marks 6
Foundation Module
20 Marks
(Module Exam)
Hematology Module
80 Marks
(Semester Theory)
100
II Marks 6
Hematology Module
20 Marks
(Module Exam)
Foundation Module
a
(Viva)
50 Marks 3
100
III Marks
Hematology Module
b
(Viva)
50 Marks 3
Semester-1 Total Credit Hours 18
137
138
SEMESTER -2
Locomotor System-1 Module 8 Weeks 9 Credit Hours
Respiratory System-1 Module 4 Weeks 4.5 Credit Hours
Cardiovascular System -1 Module 4 Weeks 4.5 Credit Hours
139
LOCOMOTOR MODULE
(LCM 1)
Semester 2
First Year MBBS
140
Spiral Sem. Modules

II

4 Week
wks
Second th
Spiral th
Trauma, 6 week
3 week 8 Weeks
/ Burns 2 wk
2 Weeks
th
th
PARALLEL THEMES:
141
MODULE COMMITTEE:
Dr Naheed Khan (focal person) Professor of Anatomy, DUHS

Dr. Khalida Parveeen, Professor of Anatomy, DUHS
Prof. Zeba Haque Professor of Biochemistry, DUHS
Prof. Mahmood Hasan Professor of Pathology, DUHS
Prof. Saud Hasan Professor of Pharmacology, DUHS
Prof. Nighat Nisar Professor of Community Medicine, DUHS
Dr. Yasmeen Taj Professor of Pathology, DUHS
Dr. Muhammad Rafique Professor of Anatomy, DUHS
Dr. Kelash Nankani Professor of Physiology, DUHS
Dr . Naila Naeem Shahbaz Associate Professor of Neurology,DUHS
Documented & Coordinated by:
DR. SABAHAT ZAIDI
Reviewed by:
Module committee
142
RATIONALE
Timely diagnosis and management of bony, cartilaginous and neuromuscular disorders is

essential to prevent disability and morbidty. A sound knowledge of structure and function of
locomotor system forms the basis of understanding the rationale of diagnosis and
mangment of the of limb disordres.
TERMINAL OBJECTIVE
By the end of this module the students should be able to:
Describe anatomy of upper and lower limbs.

Explain biochesmitry of extraceullar matrix related to cartilage and bones.
Classify histology & embryology of bones, cartilages and muscles.
Identify the roll and biochemistry of calcium, vit d and other minerals.
Enlist and discribe pathophsyiology of different arthropathies and highlight its distinctive
clinical findings.
Recognize different pharmaceutical agents used to treat arthropathies.
Enlist and describe pathophysiology of different musculopathies and highlight its distinctive
clinical findings.
Intrepret investigations used to diseases involving locomotor system.
143
LEARNING OBJECTIVES OF THE MODULE
Objectives of module are listed in following grid along with contents and teaching
methodology
Lectures
Demo:
Tutorials
Practical
CBL / SBL
Self Study
Library
Digital
spotting
Practical /
One Best, EMQS
Skills Lab
viva
Faculty
Topic / Content
Objectives (REGULAR)
Describe the LCM 1 Ane 1 Development 1 * *

importance of of mesoderm, Paraxial
mesoderm in Anatomy Mesoderm and Sclero
embryological Myotome and formation of
basis of the cartilAnges
diseases.
Identify the LCM 1 Anh 1 Classification& 1 * * *
congenital histology of cartilAnges
anomalies of Anatomy
cartilAnges by LCM 1 Anh 2 Histology of 1.5 * * *
discussing its cartilAnge
structure and LCM 1 Bio 1 Chemistry of 1
chemistry Biochemistry * *
cartilAnges,
LCM 1 Anh 3 Classification 1.5 * * *

& histology of bones
Anatomy LCM 1 Anh 4 Bone 1.5 * * *
LCM 1 Ane 2 Development 1.5 * *

of Bone, cartilAnge & joints
Correlate the LCM 1 Bio 2 Chemistry of 1
types, structure * *
Bone & the role of
and function of hormones in modeling &
bones and the Biochemistry,
remodeling
mechanism of LCM 1 Bio 3 Role of 1.5 * *
bone modeling parathyroid hormone,
and remodeling calcitonin + Vit D in bone
with modeling & remodeling
background LCM 1 Pth 1 Deficiency 1 * *
knowledge of states of Vitamin D
mineral Pathology LCM 1 Pth 2 Types and 1
metabolism * *
important clinical
with their manifestations of
consequences Osteoprosis
LCM 1 Pha 1 Ca Preps, Vit D 1 * *
preps,
Pharmacology
LCM 1 Pha 2 Drugs used in 1 * *
osteoporosis(Biphosphonate
II & other related drugs)
Integrated LCM 1 Cbl 1 Osteomalacia 1.5 * *
learning
144
Lectures
Demo:
Tutorials
Practical
CBL / SBL
Self Study
Library
Digital
spotting
Practical /
One Best, EMQS
Skills Lab
viva
Faculty
Topic / Content
LCM 1 Ang 1 Osteology of 1.5 * *

clavicle
LCM 1 Ang 2 Osteology of 1.5 * *

Anatomy scapula
Identify break LCM 1 Ang 3 Osteology of 1.5 * *
in weight humerus
LCM 1 Ang 4 Muscles of 1.5 * *
transmission
pectoral girdle
from upper
limb to axial LCM 1 Pth 3 Fractures ; 1
Pathology * *
skeleton due to bone repair
fractures of
bones of LCM 1 Ort 1 Fractures & 1 * *
pectoral girdle dislocation of upper limb
& resulting LCMOPAEDIC
disabilities LCM 1 Ort 2 Soft tissue * *
disorders of upper limb
Integrated LCM 1 Cbl 2 Fracture of 1.5 * *

learning clavicle
LCM 1 Ang 5 Muscles of 1.5 * *

shoulder region with nerve
Correlate the Anatomy supply & action & scapular
clinical anastomosis
manifestation LCM 1 Ang 6 Shoulder joint 1.5 * *
of shoulder & its movements
region for e.g. LCM 1 Pth 4 Joint inflamm., 1
winging * *
types of arthritis (OA) 1
scapula and
drooping of Pathology LCM 1 Pth 5 Joint inflamm., 1 * *
shoulder by
relating the types of arthritis (RA) 2
muscles, LCM 1 Pth 6 Patho * *
ligaments and physiology of bone infection
neurovascular
LCM 1 Pha 3 Drug used for 1 * *
bundle of
arthritis: NSAIDs, Narcotic
axillary and
scapular analgesics (acetaminophen)
region. Types LCM 1 Pha 4 Drug used for 1 * *
of Pharmacology
arthritis: NSAIDs, Non-
Osteoarthritis, narcotic analgesics (Aspirin)
with
pathogenesis LCM 1 Pha 5 Overview 1 * *
DMARDs, 1
immunosuppressant,
LCM 1 Pha 6 DMARDs, 2 1.5 * *
corticosteroids
Acetaminophen
Recognize the LCM 1 Ane 3 Development 1.5 * *
congenital of LimBeh Congenital
anomalies of Anatomy Anomalies of limBeh
limBeh by
knowing their
145
Lectures
Demo:
Tutorials
Practical
CBL / SBL
Self Study
Library
Digital
spotting
Practical /
One Best, EMQS
Skills Lab
viva
Faculty
Topic / Content
development
Lectures
Demo:
Tutorials
Practical
CBL/SBL
Self Study
Library
Digital
spotting
Practical /
BCQs,SEQs,
Lab
EMQS
Skills
viva
Modes of information Transfer Assesmen

t
Anatomy LCM 1 Ang 7 Structure of 1 * *
typical spinal nerve A
LCM 1 Phy 1 Electrical 1 * *
Properties of neurons
(RMP)
LCM 1 Phy 2 Generation 1.5 * *
and propAngation of
action potential.
LCM 1 Phy 3 Functional 1 * *
classification of nerve
Identify types of fibers
LCM 1 Phy 4 Synaptic 1 * *
neuropathies due transmission aspects of
to damAnge to Physiology neuromuscular
myelin sheath and transmission
LCM 1 Phy 5 Pain 1 * *
axons by applying
LCM 1 Phy 6 Introduction 1.5 * *
the knowledge of
to power lab & Recording
structure and of NCV's
function LCM 1 Phy 7 Simple 1.5 * *
muscle twitch
of nerves LCM 1 Phy 8 Tetanization 1.5 * *
& Summation
LCM 1 Phy 9 Fatigue 1.5 * *
Biochemistry LCM 1 Bio 4 Chemistry of 1.5 * *
neuro-transmitter
NEUROLOGY LCM 1 Neur 1 1 * *
Examination of muscles &
nerves of upper limb
Pharmacolog LCM 1 Pha 7 Pain 1 * *
y manAngement
Identify the LCM 1 Phy 10 Disorders 1 * *
Disorders of of neuromuscular
neuromuscular transmission
Physiology
transmission by
relating them with
physiology of
neuromucular
junction 146
LCM 1 Ane 4 1 * *
Recognize the basis Development of Muscle
Anatomy
of myopathies and LCM 1 Anh 5 Histology of 1.5 * *
muscular Muscle
dystrophies by
LCM 1 Phy 11 Properties 1 * *
identifying the
of muscle fiber
structure and
functions of LCM 1 Phy 12 Mechanism 1 * *
muscles. of skeletal muscle
contraction
Physiology Differentiate
Physiological basis of
LCM 1 Phy
smooth 13 Muscular
muscle 1 * *
adaptation
contractionto exercise
with skeletal
Muscle Metabolism
muscle contraction
LCM 1 Phy 14 EMG 1.5 * *
recording
Identify the lesions LCM 1 Ang 8 Formation 1.5 * *
of brachial plexus , and relations of Brachial
with the knowledge Anatomy plexus Cutaneous Supply
LCM 1 Ang 9 Nerve 1.5 * *
of its structure and \ dermatome of Upper
injuries of upper limb
formation. limb Lectures
Demo:
Tutorials
Practical
/CBL/SBL
Self Study
Library
Digital
spotting
Practical /
BCQs, SEQs
Skills Lab
EMQS
viva
Faculty
Assesment
LCM 1 Ang 10 Axilla 1.5 * *
a
Boundaries and contents:
Axillary Artery &
Vein,axillary lymph nodes
LCM 1 Ane 5 Development 1 * *
Anatomy
& histology of mammary
gland
Correlate the
structure of LCM 1 Ang 11 Gross 1.5 * *
breast with Anatomy of Breast
special emphasis
on lymphatic LCM 1 Phy 15 Physiology of 1 * *
PHYSIOLOGY lactation
drainAnge of
upper limb in LCM 1 Pth 7 Non 1 * *
carcinoma breast neoplastic lesions of
breasrt
PATHOLOGY
LCM 1 Pth 8 Neoplastic 1 * *
lesions of breasrt
Integrated LCM 1 Cbl 3 Mass in the 1.5 * *

learning breast
Identify various LCM 1 Ang 12 Muscles and 1.5 * *

Anatomy nerves of arm
nerve injuries in
the arm at
147
different levels Integrated LCM 1 Cbl 4 Supra condylar 1.5 * *
learning fractures of humerus
Recognize the LCM 1 Ang 13 Brachial 1.5 * *

importance of Anatomy vessels
brachial artery
Identify the LCM 1 Ang 14 Osteology of 1.5 * *

clinical Ulna
manifestations LCM 1 Ang 15 Osteology of 1.5
of lower radial
* *
radius and hand
fractures in
Anatomy
correlation to
the knowledge
of structures of
forearm
Recognize the LCM 1 Ang 16 Elbow joint& 1 * *

importance of arterial anastomosis
blood vessels around elbow
around the LCM 1 Ang 17 Superficial 1 * *
elbow joint with Anatomy veins, lymphatics & lymph
nodes of upper limb
localization of
LCM 1 Ang 18 Boundaries 1.5 * *
ante-cubital
and contents of cubital
veins for fossa
drawing blood
Lectures
Demo:
Tutorials
Practical
/CBL/SBL
Self Study
Library
Digital
spotting
Practical /
BCQs, SEQs
Skills Lab
EMQS
viva
Faculty
Assesment
LCM 1 Ag 10 Axilla 1.5 * *
a
Boundaries and contents:
Axillary Artery &
Vein,axillary lymph nodes
LCM 1 Ae 5 Development 1 * *
Anatomy
& histology of mammary
gland
Correlate the
structure of LCM 1 Ag 11 Gross 1.5 * *
breast with Anatomy of Breast
special emphasis
on lymphatic LCM 1 Phy 15 Physiology 1 * *
PHYSIOLOGY of lactation
drainage of
upper limb in LCM 1 Pth 7 Non 1 * *
carcinoma breast neoplastic lesions of
breasrt
PATHOLOGY
LCM 1 Pth 8 Neoplastic 1 * *
lesions of breasrt
Integrated LCM 1 Cbl 3 Mass in the 1.5 * *

learning breast
148
LCM 1 Ag 12 Muscles and 1.5 * *
Identify various Anatomy nerves of arm
nerve injuries in
the arm at
different levels Integrated LCM 1 Cbl 4 Supra 1.5 * *
learning condylar fractures of
humerus
Recognize the LCM 1 Ag 13 Brachial 1.5 * *
importance of Anatomy vessels
brachial artery
Identify the LCM 1 Ag 14 Osteology of 1.5 * *

clinical Ulna
manifestations LCM 1 Ag 15 Osteology of 1.5 * *
of lower radial radius and hand
fractures in
Anatomy
correlation to
the knowledge
of structures of
forearm
Recognize the LCM 1 Ag 16 Elbow joint& 1 * *

importance of arterial anastomosis
blood vessels around elbow
around the LCM 1 Ag 17 Superficial 1 * *
elbow joint with Anatomy veins, lymphatics & lymph
nodes of upper limb
localization of
LCM 1 Ag 18 Boundaries 1.5 * *
ante-cubital
and contents of cubital
veins for fossa
drawing blood
Lectures
Demo:
Tutorials
Practical
CBL/SBL
Study
Self
Library
Digital
/ spotting
Practical
EMQS
BCQs,
SEQs
viva
Lab
Skills
LCM 1 Ang 19 Muscles of front of 1.5 * *

forearm& flexor retinaculum
LCM 1 Ang 20 Muscles of back of 1.5 * *

forearm extensor retinaculum
LCM 1 Ang 21 Nerves and vessels of 1.5 * *

forearm
Enumerate the
musles and Anatomy LCM 1 Ang 22 Muscles of 1.5 * *
joints of fore hand,movement of
arm and hand thumb,palmaraponeurosis,anatomi
involved in cal snuff box
daily life LCM 1 Ang 23 Nerves & vessels of 1.5 * *
activities hand
LCM 1 Ang 24 Wrist joints & small 1.5 * *
joints of hands
LCM 1 Ang 25 Spaces of palm 1.5 * *
Skill Skills Vital Signs: arterial puncture 1. * *

5
149
Mark the LCM 1 Ang 26 Surface marking of 1.5 * *
surface structures of Upper Limb
anatomy of
major nerves
Anatomy
and vessels of
upper limb ,
clinical
importance of
cross section
Differentiate LCM 1 Rad 1 Normal radiological 1 * *
between the anatomy of upper limb
normal and
Radiology LCM Rad 2 Cross section of upper 1
abnormal * *
radiographs of limb
the upper limb
Identify the LCM 1 Ang 27 Introduction of 1 * *

effects of break lower limb
in weight
LCM 1 Ang 28 Osetology of Hip 1.5 * *
transmission Bone I
from axial
skeleton to Anatomy LCM 1 Ang 29 Osetology of Hip 1.5 * *
lower limb due Bone II
to fractures of LCM 1 Ang 30 Osetology of femur 1.5 * *
bones of pelvic
girdle & thigh.
LCM 1 Ang 31 Femur :attachments 1.5 * *
Identify the LCM 1 Ang 32 Formation 1. * *

clinical effects lumbosacral plexus, cutaneous 5
of lumbosacral Anatomy supply\dermatomes of lower limb
root and nerve LCM 1 Ang 33 Nerve injuries of 1 * *
compression. lower limb
LCM 1 Neur 2 Clinical examination 1 * *

of nerves of lower limb
LCM 1 Neur 3 Neuromuscular 1. 1 * *

disorders(Neuropathy) 5
Neurology
LCM 1 Ang 34 Veins of lower limb . 1. * *
Formation of great & small 5
saphenous veins + Lymphatic
DrainAnge
LCM 1 Ang 35 Deep fascia of 1.5 * *
thigh,iliotibial tract, saphenous
opening
Recognize the
importance of LCM 1 Ang 36 Muscles of anterior 1 * *
compartments compartment of thigh
of lower limb & LCM 1 Ang 37 Nerves & vessels of 1.5
the injuries as a
Anatomy * *
anterior compartment of thigh
result of
wound of LCM 1 Ang 38 Medial compartment 2 * *
thigh. of thigh
LCM 1 Ang 39 Posterior 1 * *
compartment of thigh
150
LCM 1 Ang 40 Popliteal fossa 1. * *
5
Integrated LCM 1 Cbl 5 Gunshot injury of thigh 1. * *

learning involving adductor canal 5
Differntiate LCM 1 Ang 41 Femoral Sheath & 2 * *

femoral from Anatomy Femoral ring and femoral canal +
inguinal hernia femoral triangle & its contents
LCM 1 Ang 42 Gluteal region 1.5 * *

Indicate the
importance of Anatomy
structures in
gluteal region
with special Integrated LCM 1 Cbl 6 Sciatica 1. * *
reference to learning 5
Sciatica
Discuss hip LCM 1 Ang 43 Hip joint & 1. * *

joint & its movements 5
movments to
Anatomy
understand its
deformities &
dislocation
LCM 1 Ang 44 Osteology of Tibia 1.5 * *
Explain gross
LCM 1 Ang 45 Osteology of Fibula 2 * *
features of
& bones of foot
bones of foot Anatomy
muscles,vessels LCM 1 Ang 46 Muscles, nerves and 2 * *
and nerves vessels of Anterior & Lateral
Compartment of Leg
Recognize the LCM 1 Ang 47 Muscles,neves and 1 * *
importance of vessels of posterior compartment of
soleal pump in Anatomy leg
relation to deep
vein
Discuss knee LCM 1 Ang 48 Gross 1. * *
thrombosis
joint & its features,movement and applied 5
movments to Anatomy anatomy of knee joint & genicular
understand its anastomosis
deformities
Discuss LCM 1 Ang 49 Muscles, 1.5 * *
musculature Anatomy neurovascular supply of foot
and
neurovascular
Identify flat LCM 1 Ang 50 Ankle and superior 1 * *
supply of foot
foot and its and inferior tibiofibular joints,
mechanical joints of foot
Anatomy
effects
LCM 1 Ang 51 Arches of foot 1 * *
Mark the LCM 1 Ang 52 Surface Anatomy of 1.5 * *

surface Anatomy lower limb
anatomy of
major nerves
Differentiate LCM 1 Rad 3 Normal x-ray of lower 1.
and vessels
* *
between theof limb 5
lowerlimb
normal and Radiology
abnormal LCM 1 Rad 4 Cross section of lower 1 * *
radiographs of limb
the lower limb.
Community LCM 1 Com 1 Study Design with 1 * *
medicine measures of association
151
LCM 1 Com 2 Normal Distribution * *
curve
LCM 1 Com 3 Standard Error And 1. * *

Estimation of 95% Confidence 5
Interval
LCM 1 Com 4 Health transition 1 * *
LCM 1 Com 5 Injuries and accidents 1 * *
LCM 1 Com 6 Disaster 1 * *
ManAngement and control
LCM 1 Com 7 Health promotion 1 * *
and Health education
LCM 1 Com 8 Health of elderly 1 * *

Behavioral LCM 1 Beh 1 Medical Ethics 1 * *
sciences
LCM 1 Beh 2 Common ethical 1 * *
Omissions in Medical Practice
152
LOCOMOTOR MODULE
TIME TABLE
FIRST WEEK
THEME: STRUCTURE AND FUNCTION OF BONES AND
CARTILAGES
Day 8.30 -9.30 9.30- 10.30 11.00-12.30 1.30-3.00
Anatomy Demo
Anatomy Anatomy Demo Osteology of clavicle
Anatomy Osteology of Scapula A+C= FACULTY
Classification &
DAY
Introduction to A= FACULTY VENUE VENUE
histology of
1 locomotor system B= FACULTY VENUE B= FACULTY VENUE
FACULTY
cartilages C= FACULTY VENUE D= FACULTY HALL
FACULTY
VENUE D= FACULTY VENUE 102
VENUE
E= FACULTY VENUE E= FACULTY BIO
LAB
Anatomy
Embryology Anatomy Demo
Development of Osteology of
Biochemistry mesoderm, Anatomy Humerus
DAY
Chemistry of Paraxial Classification & A= FACULTY VENUE
2 cartilages Mesoderm and Histology of bones B= FACULTY VENUE
FACULTY Sclero Myotome FACULTY C= FACULTY VENUE
VENUE and formation of VENUE D= FACULTY VENUE
cartilages E= FACULTY BIO
FACULTY LAB
VENUE
Biochemistry Anatomy Demo

Community Chemistry of Muscles of pectoral
Medicine Bone and the girdle
DAY
Study of design role of A= FACULTY
3 with measures of hormones in AD VENUE
association modeling and B= FACULTY VENUE
FACULTY remodeling C= FACULTY
VENUE FACULTY D= FACULTY
VENUE E= FACULTY
Anatomy Demo
PHARMACOLOGY Pathology
Muscles of shoulder
Ca Preps, Vit. D Describe the
region with nerve
DAY
preps, and other deficiency states Self Study
supply and actions
4 related minerals of Vitamin D
FACULTY
A+C= FACULTY VENUE
FACULTY
B= FACULTY VENUE
VENUE D= FACULTY VENUE
VENUE
E= FACULTY VENUE
153
SEMESTER II 2011-2012
LOCOMOTOR MODULE WEEK-II
Theme: Diseases of Bones & Nerves
Day 8.30 -9.30 9.30- 10.30 11.00-12.30 1.30 -3.00

1)GP A:Histology practical:
2) GP B:Biochemistry Tut. : Role of
Cartilage
Pathology Parathyroid Hormones, calcitonin + Vit-D
SELF Types and Embryology in Bone Modeling and remodeling,
ASSESMENT important clinical Development of FACULTY
DA 3) GP C:Physiology practical
TEST manifestations of Cartilage, Bones and
Y1 Introduction to Power lab
FACULTY Osteoporosis Joints
VENUE FACULTY FACULTY VENUE FACULTY
VENUE 4) GP D: Self Study
5) GP E: CBL
Pathology Pharmacology 1. B
Drugs used in Anatomy 2. C
Patho-physiology
DA osteoporosis Shoulder joint & its 3. D
of Bone Infection
Y2 (Biphosphonates movements 4. E
FACULTY
II FACULTY VENUE
VENUE 5. A
and other related " Anatomy Demo 1. C
drugs
5 batches 2. D
FACULTY VENUE
Community Formation and 3. E
Medicine Anatomy relations of Brachial 4. A
Structure of plexus 5. B
DA Cutaneous Supply \
Disaster Typical Spinal
Y3 dermatome of Upper
Management Nerve
FACULTY FACULTY VENUE limb"
A: FACULTY VENUE
VENUE B: FACULTY VENUE
C: FACULTY VENUE
D: FACULTY VENUE
E: FACULTY VENUE
Pathology 1. D
Joint Physiology Embryology 2. E
inflammation., Electrical Development of 3. A
DA
types of arthritis Properties of Limbs Congenital 4. B
Y4
(OA) I neurons (RMP Anomalies of limbs 5. C
FACULTY FACULTY VENUE FACULTY
VENUE
Pathology
Physiology Physiology
Joint
Functional Generation and
inflammation.,
DA classification of propagation of action
types of arthritis (
Y5 nerve fibers potential
RA) II
FACULTY FACULTY
FACULTY
VENUE VENUE
VENUE
1. E
Pharmacology Anatomy Demo 5 2. A
Drug used for batches 3. B
arthritis: NSAIDs, Axilla Boundaries and
non-narcotic 4. C
contents Axillary Artery
analgesics & Vein ,axillary lymph
5. D
DA (acetaminophen) and nodes& their relationship
other drugs used; BS
Y6 A: FACULTY VENUE
Diacirine and B: FACULTY VENUE
hyaluronic acid and FACULTY C: FACULTY VENUE
chondroitin sulfate D: FACULTY VENUE
and etc
FACULTY VENUE
FACULTY VENUE
154
SEMESTER II 2011-2012
LOCOMOTOR MODULE WEEK-III
THEME MAMMARY GLAND
DAY 8.30 -9.30 9.30- 10.30 11.00-12.30 1.30-3.00

Anatomy Demo 5
SELF BATCHES
ASSESMENT
PHARMACOLOGY ANATOMY Muscles and nerves of arm
DAY TEST
Drugs used for arthritis: Gross Anatomy of Breast A= FACULTY VENUE
1 (acetaminophen)
FACULTY FACULTY VENUE B+E= FACULTY VENUE
VENUE
FACULTY VENUE
C= FACULTY VENUE
D= FACULTY VENUE
A= Histology Practical : bone
Anatomy Demo 5 BATCHES
B= Biochemistry Practical Brachial Vessels+ scapular
Chemistry of Neuro anastomosis
ANATOMY
transmitters A= FACULTY HISTOL
Histology
and PHARMACOLOGY FACULTY LAB
DAY Development of Drugs used for arthritis:
C= Physiology practical B= FACULTY VENUE
2 NSAIDs, (Aspirin) C= FACULTY VENUE
Mammary gland NCV Power lab
FACULTY VENUE D= FACULTY VENUE
FACULTY FACULTY
VENUE D=- CBL E= FACULTY VENUE
E= Pharmacology Tutorial
Management of rheumatoid
arthritis:
PHARMACOLOGY* Anatomy Demo 5 BATCHES
PHYSIOLOGY Management of 1. B Osteology of Ulna
Physiology of rheumatoid arthritis: 2. C A= FACULTY VENUE
DAY lactation DMARDs, immuno- B+E= FACULTY VENUE
3. D
3 FACULTY suppressants, 4. E C= FACULTY VENUE
VENUE corticosteroids 5. A D= FACULTY VENUE
FACULTY VENUE
Anatomy Demo 5 BATCHES
Osteology of radius and hand
PATHOLOGY 1. C A= FACULTY HISTOL
Non neoplastic 2. D
DAY lesion of Breast SELF STUDY 3. E
LAB
4 B= FACULTY VENUE
FACULTY 4. A
C= FACULTY VENUE
VENUE 5. B
D= FACULTY VENUE
E= FACULTY VENUE
PATHOLOGY COMMUNITY 1. D
Neoplastic lesion MEDICINE 2. E
DAY of Breast Normal Distribution 3. A
5 FACULTY Curve 4. B
VENUE FACULTY VENUE 5. C
Anatomy
Cubital Fussa
A= FACULTY HISTOL
CLINICAL PHYSIOLOGY 1. E LAB
DAY FACULTY Properties of muscle 2. A
B= FACULTY VENUE
Arthritis fiber 3. B
6 4. C C= FACULTY VENUE
FACULTY FACULTY
5. D D= FACULTY VENUE
VENUE VENUE
E= FACULTY VENUE
155
LOCOMOTOR MODULE
SEMESTER II, WEEK IV (4) TIME TABLE
THEME: FOREARM AND HAND
DAY 8.30 -9.30 9.30- 10.30 11.00-12.30 1.30-3.00

Anatomy Anatomy Demo
Physiology
Muscles of front of Forearm, flexor 5 BATCHES
Mechanism of retinaculum & space of parona Muscles of back of forearm& extensor
SELF skeletal muscle
ASSESSMENT 1. A= FACULTY VENUE retinaculum
DAY TEST
contraction 2. B = FACULTY VENUE 1. A= FACULTY VENUE
1 FACULTY Differentiate basis 3. C = FACULTY VENUE 2. B = FACULTY VENUE
VENUE of smooth muscle 4. D = FACULTY VENUE 3. C = FACULTY VENUE
contraction 5. E = FACULTY VENUE 4. D = FACULTY ARVENUE
FACULTY VENUE 5. E = FACULTY VENUE
HISTO PRACTICAL: Anatomy Demo
Physiology A= Histology of Muscles VENUE 5 BATCHES
Synaptic Physiology CBL=B Blood Vessels and Nerves of Forearm
transmission aspects Disorders of Physiology Practical =C (EMG) 1. A= FACULTY VENUE
DAY of neuromuscular neuromuscular 2. B = FACULTY VENUE
VENUE
2 transmission transmission VENUE = D1= FIRST AID SKILLS: 3. C = FACULTY VENUE
FACULTY FACULTY VENUE VENUE 4. D = FACULTY ZEELA
VENUE VENUE
5. E = FACULTY VENUE
DAY
3
Anatomy Demo
Physiology
5 BATCHES
Muscular 1. B Muscles of hand, movement of thumb,
adaptation to Anatomy 2. C Palmar
DAY exercise Development of 3. D aponeurosis, anatomical snuff box
4 Muscle Muscle 4. E 1. A= FACULTY VENUE
Metabolism FACULTY VENUE 5. A 2. B = FACULTY VENUE
FACULTY 3. C = FACULTY IN VENUE
VENUE 4. D = FACULTY RAN VENUE
5. E = FACULTY ADVENUE
1. C
Anatomy 2. D
Elbow joint & 3. E
Physiology 4. A
DAY Anastomosis
pain
Around 5. B
5 FACULTY VENUE
FACULTY
VENUE

Superficial Veins, 1. D 5 BATCHES
Lymphatics And Pharmacology 2. E Nerves and Vessels of hand
DAY Lymph Nodes Of Pain management: 3. A 1. A= FACULTY VENUE
6 Upper Limb narcotic analgesics 4. B 2. B = FACULTY VENUE
FACULTY FACULTY VENUE 5. C 3. C = FACULTY VENUE
VENUE 4. D = FACULTY VENUE
5. E = FACULTY VENUE
156
LOCOMOTOR MODULE
SEMESTER II, WEEK V (5) TIME TABLE
THEME: APPLIED ANATOMY OF UPPER LIMB + INTRODUCTION OF LOWER LIMB
Day 8.30 -9.30 9.30- 10.30 11.00-12.30 1.30 -3.00
DAY
1 Self study
DAY
2 Self study
Anatomy Demo
Wrist joint and small joints of 1=E
SELF Radiology Faculty
hand 2=A
ASSESSMENT Normal radiological
DAY A= FACULTY VENUE 3=B
TEST anatomy of upper
3 B = FACULTY 4=C
FACULTY limb
C = FACULTY VENUE 5=D
VENUE FACULTY VENUE
D = FACULTY VENUE LAST WEEK BATCH
E = FACULTY VENUE
Anatomy Demo
RADIOLOGY Faculty of Neurology Surface anatomy of upper
Faculty Cross Examination of Anatomy lecture limb
DAY sections of upper muscles and nerves Nerve injuries of upper limb A= FACULTY VENUE
4 limb of upper limb FACULTY VENUE B = FACULTY VENUE
FACULTY FACULTY C = FACULTY ENUE
VENUE VENUE
E = FACULTY VENUE
Anatomy Demo
ORTHOPAEDIC Hip Bone I
Faculty ANATOMY A. = FACULTY OSSAIN
DAY Trauma to upper Introduction of VENUE
limb (Fractures of lower limb B. = FACULTY VENUE
5 dislocation)
FACULTY VENUE C. = FACULTY VENUE
FACULTY
D. = FACULTY VENUE
VENUE
E. = FACULTY VENUE
Anatomy Demo
Hip Bone II
Pathology Orthopedic
A. = FACULTY VENUE Community Medicine
DAY Fractures and bone Soft tissue disorders
repair B. = FACULTY FACULTY Standard Error And 95%
of upper limb Confidence Interval
6 FACULTY FACULTY
VENUE
VENUE C. = FACULTY VENUE FACULTY VENUE
VENUE
D. = FACULTY FACULTY
FACULTY VENUE
157
LOCOMOTOR MODULE
SEMESTR-II
Time Table; Week VI (6) Theme; Thigh
Day 8.30 -9.30 9.30- 10.30 11.00-12.30 1.30-3.00

1. A=Anatomy Demo
spaces of palm
Anatomy Demonstration FACULTY VENUE
in 5 batches 2. B= Physiology
Self Practical
DAY Community Medicine Femur: osteology
assessment Simple Muscle Twitch
Health Transition A+B = FACULTY VENUE
1 test FACULTY VENUE C= FACULTY ATTA UR FACULTY
VENUE 3. C= CBL
REHMAN
D+E = FACULTY VENUE 4. D= Skills Lab
FIRST AID SKILLS
5.E= Self Study
Anatomy Demonstration
Anatomy Demonstration in 5 batches 1. B
in 5 batches Deep fascia of thigh, iliotibial tract,
2. C
DAY Femur : attachments saphenous opening
3. D
2 A+B = FACULTY AT VENUE A+B = FACULTY VENUE
4. E
C= FACULTY VENUE C= FACULTY VENUE
5. A
D+E = FACULTY VENUE D+ E = FACULTY SAIN
BIO LAB
Anatomy lecture 1. C
Anatomy lecture
Behavioral Muscles of anterior 2. D
DAY Formation of lumbosacral
sciences compartment of thigh 3. E
3 VENUE plexus
FACULTY 4. A
VENUE FACULTY
5. B
in 5 batches
Nerves and vessels of anterior
1. D
Anatomy lecture compartment of thigh
2. E
DAY Femoral Sheath & Femoral ring and A = FACULTY RAN VENUE
3. A
4 Adductor canal--- B= FACULTY AH
VENUE 4. B
Femoral Triangle and its contents
C= FACULTY AT VENUE 5. C
FACULTY VENUE
D= FACULTY VENUE
E= FACULTY VENUE
Anatomy Demonstration Anatomy Demonstration

in 5 batches in 5 batches
DAY
Medial compartment of thigh Gluteal Region
5 A+B+C = DR. NASAR VENUE
A+B = FACULTY VENUE
C= FACULTY VENUE D+E = DR. SABAHT VENUE
D+E = FACULTY VENUE
in 5 batches
Community
Posterior compartment 1. E
Medicine
/back of the thigh Anatomy lecture 2. A
DAY FACULTY
ccidents &
A+B = FACULTY AN Hip joint and movements 3. B
6 Injures VENUE
FACULTY VENUE 4. C
FACULTY C= FACULTY AIN
5. D
VENUE
VENUE
D+E = FACULTY H
VENUE
158
LOCOMOTOR MODULE
SEMESTER II, TIME TABLE: WEEK VII(7th)
THEME ; LEG AND FOOT
Day 8.30 -9.30 9.30- 10.30 11.00-12.30 1.30-3.00
1-Physiology A
Anatomy DEMO 5 BATCHES Tetanization &Summation
COMMUNITY Tibia FACULTY
SELF MEDICINE
2. B= SELF STUDY
ASSESSMENT Health promotion A+B= FACULTY VENUE
DAY
TEST and health 3. C= CBL
1 C= FACULTY AN VENUE
FACULTY education
VENUE FACULTY D= FACULTY 102 HALL 4- D=ANATOMY MUSEUM
VENUE E= FACULTY VENUE Model Study of UPPER LIMB
5. E= SKIKLL LAB:Arterial
puncture
Anatomy DEMO 5 BATCHES 1. B

Anatomy
Fibula & bones of foot 2. C
DAY Popliteal fossa
A= FACULTY 102 HALL 3. D
2 DR. NAHEED KHAN
B+C= FACULTY ZEELA VENUE 4. E
VENUE
D+E= FACULTY VENUE 5. A
DAY
3
Anatomy DEMO 5 BATCHES Anatomy LECTURE 1. C

Anterior & Lateral compartment of leg Superficial Veins of Lower limb 2. D
DAY Formation of Great & Small
A= FACULTY MRAN VENUE 3. E
4 B= DR. IRSHAD VENUE Spahneous veins + Revision of 4. A
C= FACULTY VENUE Fibula 5. B
FACULTY VENUE
Anatomy DEMO 5 BATCHES

Posterior Compartment of Leg 1. D
Muscles ,Posterior Tibial Vessels and 2. E
DAY
Tibial Nerve FACULTY A+B = 3. A
5 FACULTY VENUE 4. B
C= FACULTY EELA 102 HALL 5. C
D+E= FACULTY VENUE
1. E
Anatomy DEMO 5 BATCHES
2. A
Anatomy Demo Anatomy Lecture
DAY 3. B
Muscles of foot Knee Joint
6 4. C
A+B+C = FACULTY FACULTY FACULTY VENUE 5. D
VENUE
159
LOCOMOTORMODULE
SEMESTER II, TIME TABLE: WEEK VIII (8th)
THEME: NEUROPATHY
Days 8.30 -9.30 9.30- 10.30 11.00-12.30 1.30-3.00
A2= VENUE arterial
puncture.
Anatomy Demo
A1= Self Study
Ankle Joint, Superior Anatomy
B= Physiology Practical
SELF ASSESSMENT and Inferior Neurovascular Supply of foot
Fatigue
DAY TEST Tibiofibular Joints & A+B = FACULTY VENUE
FACULTY
1 FACULTY Transverse Tarsal C+D= FACULTY VENUE
VENUE Joint E= FACULTY 102 HALL C= Anatomy Museum
Model Study. FACULTY
FACULTY VENUE
D= CBL
E= Self study
Anatomy 1. B2
Faculty of Neurology Radiology Faculty 2. C
DAY Clinical examination of Nerve Injuries of
Normal X-Rays of Lower Limb 3. D
2 Nerves of Lower Limbs Lower Limb 4. E
FACULTY VENUE FACULTY VENUE
FACULTY VENUE 5. A
Orthopedic Faculty
Clinical Faculty of Neurology 1. C2
Anatomy Trauma to lower
Neuromuscular disorders 2. D
DAY Arches of foot Limb
(Neuropathy) 3. E
3 VENUE (Fractures &
FACULTY 4. A
FACULTY dislocations )
VENUE 5. B
VENUE
Anatomy Demo
Radiology Faculty 1. D2
COMMUNITY Surf FACULTY anatomy of
2. E
DAY Cross Sections of Lower MEDICINE lower limb
Elderly Health 3. A
4 Limb A = FACULTY 102 HALL
FACULTY VENUE 4. B
B+C= FACULTY VENUE
FACULTY VENUE 5. C
D+E = FACULTY VENUE
FACULTY OF
Orthopedic Faculty VASCULAR SURGERY 1. E2
Deformities of Skeleton Applied vascular 2. A
DAY of lower Limb anatomy of Lower Limb 3. B
5 (Coxa Vera ,Coxa Vulga + 4. C
, Telipes Foot etc) Deep Vein Thrombosis 5. D
VENUE FACULTY VENUE
DAY
6 SELF STUDY
160
AT THE END OF THE LECTURE THE STUDENT SHOULD BE ABLE TO:
GROSS ANATOMY
1. LCM 1 Ang 1 INTRODUCTION TO LOCOMOTOR AND UPPER LIMB
Identify the extent of the upper limb.

Identify various regions of upper limb.
Describe the division of various regions into compartments.
State the contents of compartments of arm, forearm & hand.
Describe the joints of upper limb.
Apply the clinical anatomy of upper limb.
2. LCM 1 Ang 1a OSTEOLOGY OF CLAVICLE
Recognize the bone

Identify the site of bone
State the bony land marks of bone like borders ,surfaces and land
marked used for bond determination.
Describe & Demonstrate the attachments of muscles.
3. LCM 1 Ang 2 OSTEOLOGY OF SCAPULA
Recognize the bone.

Identify the site of bone.
State the bony landmarks of bone like borders, surfaces & land mark
used for bone determination.
Describe & Demostrate the attachment of muscles on scapula
4. LCM 1 Ang 3 OSTEOLOGY OF HUMERUS
Recognize the bone.

Identify the site of bone
State the bony landmarks of bone like borders, surfaces & land mark
used for bone determination.
Describe & Demostrate the attachment of muscles & ligaments.
5. LCM 1 Ang 4 MUSCLES OF THE PECTORAL GIRDLE
Recognize the role of muscles of pectoral region in stabilizing the

pectoral girdle.
List the muscle of pectoral girdle .
Describe & Demonstrate the attachments of muscle of pectoral girdle,
nerve supply and actions ( Pectoralis Major and minor,
161
Subclavius,Trapezius,Latissimus Dorsi,Rhomboid major and
minor,Levator Scapulae and Serratus anterior).
Discuss the structural organization of the clavi-pectoral fascia.
Identify the triangle of auscultation.
Describe the nerves and blood vessels of this region.
6. LCM 1 Ang 5 MUSCLES OF THE SHOULDER REGION
Recognize the extent of shoulder region.

List the muscles of shoulder region.
State the detailed structures of each muscle with respect to
Origin,
Insertion,
Nerve supply and
Action of muscles with any characteristic features.
7. LCM 1 Ang 6 THE SHOULDER JOINT & ITS MOVEMENTS
Classify the types of shoulder joint.

Describe the structure of shoulder joint.
Name the muscles acting on the joint/rotator cuff muscles.
Explain the range of mobility.
Describe the movements of shoulder joint.
Explain the clinical anatomy of the joint.
8. LCM 1 Ang 7 TYPICAL SPINAL NERVE
Define a spinal nerve.

Recognize the spinal nerve as a part of PNS.
Enumerate the spinal nerves in different regions.
Identify their location and site of emergence.
Identify various components of a typical spinal nerve.
Recall the fate of rami.
Associate the rami communicans with typical spinal nerve.
Recall the distribution of gray rami.
9. LCM 1 Ang 8 FORMATION & RELATIONS OF BRACHIAL PLEXUS CUTANEOUS
SUPPLY\ DERMATOME OF UPPER LIMB
Mention the formation of brachial plexus (roots, trunk,division, and

cords).
Discuss the relation of brachial plexus also in connection to clavicle
(Supra, retro, infra clavicular parts).
State the branches arising the different cords.
Draw the brachial plexus.
Describe cutaneous supply of arm.
162
10. LCM 1 Ang 9 NERVES OF UPPER LIMB AND THEIR INJURIES
Describe the course and branches of nerves of upper limbs.
Explain the injuries associated with these nerves.
Identify the causes and motor and sensory loss associated with nerve
injuries of upper limb.
Apply knowledge of gross anatomy to identify the deformities associated
with these nerves.
11. LCM 1 Ang 10 AXILLA
Describe the position, shape of axilla.

Describe the boundaries and muscle forming the boundaries of axilla.
Discuss the formation, course and relations of axillary vessels.
Describe arrangement and groups axillary lymph node
LCM 1 Ang 11 GROSS FEATURES OF BREAST

Describe the anatomy of breast.
Explain the relation of breast within pectoral region.
Describe the blood supply of breast.
Describe the lymphatic drainage of breast.
Relate the Anatomy of the breast with axilla.
12. LCM 1 Ang 12MUSCLES AND NERVES OF ARM
Describe the compartments of arm and how they are formed.

Identify and explain the muscles and their actions found in the arm.
Discuss the nerve supply of arm.
Describe the course of the nerves
Identify the branches of the nerves
Relate & intergrate with the clinical correlations
13. LCM 1 Ang 13BRACHIAL VESSELS AND SCAPULAR ANASTOMOSIS
Discuss the extension, relation and branches of the Brachial artery.

Describe the course of the Basilic and cephalic veins
Describe and explain the formation and purpose of the scapular
anastomosis.
14. LCM 1 Ang 14 OSTEOLOGY OF ULNA
Recognize the bone.
Determine the side of bone.
Identify the features of bone.
Identify the muscles attached to bone.
Explain clinical significance of bone.
15. LCM 1 Ang 15 OSTEOLOGY OF RADIUS & HAND

Recognize the bones of forearm & hand
Determine side of bones.
Identify the features of bones.
Identify the muscles attached to bones.
163
Describe the ossification of bones
Explain the clinical significance of bones.
16. LCM 1 Ang 16 ELBOW JOINT & ANASTOMOSIS AROUND ELBOW JOINT
Identify the morphology of the joint.

State and Identify the muscles acting on the elbow joint.
Discuss the neurovascular supply of the joint.
Describe the carrying angle and applied aspect of the joint.
Describe the anastomosis and collateral circulation.
Describe formation of anastomosis around elbow joint.
17. LCM 1 Ang 17 SUPERFICIAL VEINS, LYMPHATICS AND LYMPH NODES OF UPPER LIMB
Discuss the normal anatomy of veins of upper limb.
Differenciate between superficial and deep veins.
Discuss the features of individual superficial veins of upper limb.
Corelate the applied anatomy with the gross anatomy of superficial
veins of upper limb.
Define a lymph node.
Identify the groups of lymph nodes.
Describe groups and area of drainage of each group of lymph
nodes.
Discuss the commencement, course and termination of superficial
lymphatic vessels.
Discuss the clinical conditions related to lymphatic channels of upper
limb.
18. LCM 1 Ang 18 CUBITAL FOSSA
Describe the boundaries, the contents and the relationship among

structures of cubital fossa.
Demostrate the surface anatomy of the cubital fossa.
Explain the clinical importance of the cubital fossa.
19. LCM 1 Ang 19 THE MUSCLES OF THE ANTERIOR COMPARTMENT OF FOREARM AND
FLEXOR RETINACULUM
List the muscles of forearm.

State the nerve supply of these muscles.
Explain actions of the muscles of anterior compartment of forearm.
Describe attachment and functions of flexor retinaculum.
164
20. LCM 1 Ang 20 MUSCLES OF THE POSTERIOR COMPARTMENT OF FOREARM AND
EXTENSOR RETINACULUM
Explain the organization of muscles of posterior compartment of forearm

State the nerve supply of these muscles.
Explain the actions of the muscles of posterior compartment of forearm.
Decribe the structural organization of the Extensor Retinaculum.
21. LCM 1 Ang 21 BLOOD VESSELS & NERVES OF THE FOREARM
Discuss the different vessels & nerves in forearm.

Describe the location, destination, course & relations of radial and ulnar
arteries & their branches in forearm.
Identify and discuss the deep veins of forearm and their tributaries.
Describe the location, destination, course & relations of ulnar, radial and
median nerves & their branches in forearm.
22. LCM 1 Ang 22 MUSCLES OF HAND MOVEMENTS OF THUMB PALMAR APONEUROSIS

ANATOMICAL SNUFFBOX
Recall the structure and functions of palmar aponeurosis.

Describe the attachments, nerve supply & actions of muscles of hand.
Correlate the movements of thumb with hand anatomy.
Identify the anatomical snuffbox.
Relate applied with gross anatomy of few structures of hand.
23. LCM 1 Ang 23 VESSELS & NERVES OF THE HAND

Identify different vessels in hand.
Describe the location, destination course relations of radial and ulnar
arteries in hand.
State the branches of radial and ulnar arteries in hand.
Describe the formation of superficial and deep palmar arch, veins of
hand and their tributaries.
Discuss the nervous supply of the hand.
24. LCM 1 Ang 24 SUPERIOR & INFERIOR RADIO-ULNAR JOINTS & WRIST JOINT
Recognize the details of radio-ulnar joints.
Discuss and explain the movements occurring on these joints.
Name the muscles acting in pronation and supination.
Discuss the nerve supply and blood supply of these joints.
Describe wrist joint, nerve supply and blood supply.
Discuss clinical problems related to these joints.
165
25. LCM 1 Ang 25 SPACES OF THE PALM
Identify the different spaces of the hand on both palmar and dorsal
aspects.
Discuss the clinical importance of these spaces.
26. LCM 1 Ang 26 SURFACE ANATOMY OF UPPER LIMB
Demostarete the surface markings for various arteries of upper limb.
27. LCM 1 Ang 27 INTRODUCTION TO LOWER LIMB
Recognize different parts of lower limb.

Describe regions of lower limb.
List the bones of lower limb.
Describe the vessels and nerves of lower limb.
Identify different land marks in different regions of lower limb
28. LCM 1 Ang 28 HIP BONE I

Identify the different parts of the bone.
Discuss side determination.
Discuss muscle attachments.
Describe ligamentous attachments.
Discuss the different bones articulating with the hip bone.
29. LCM 1 Ang 29 HIP BONE II
Identify the different parts of the bone.

Discuss side determination.
Discuss muscle attachments.
Describe ligamentous attachments.
Discuss the different bones articulating with the hip bone.
30. LCM 1 Ang 30 FEMUR (OSTEOLOGY)

Identify different parts of the femur
Determine the side of the bone
Identify the surfaces and borders of the bone
31. LCM 1 Ang 31 FEMUR (ATTACHMENTS AND CLINICAL ANATOMY)
Describe the attachments of the different muscles and ligaments on the

bone
Discuss the arterial supply of the bone
Relate to the general idea about fractures of femur and other clinical
conditions
166
32. LCM 1 Ang 32 LUMBO SACRAL PLEXUS, CUTANEUS NERVES, DERMATOME MAPPING.
Discuss the formation of lumbar plexus.

List the branches of lumber plexus with their root values.
Discuss relation of the nerves with Psoas major muscle.
List the structures supplied by lumbar plexus.
Describe the formation of sacral plexus.
Describe the composition and relations of sacral plexus.
List the branches of this plexus.
Discuss the Cutaneous supply of lower limb.
Discuss few applied points about these plexuses.
33. LCM 1 Ang 33 NERVES OF LOWER LIMB AND THEIR INJURIES
Identify the names of nerves and their main branches innervating lower
limb
Identify the nerves closely related to a bone or other structure of lower
limb
Recognize the main nerves commonly vulnerable to injury
Identify the main area and loss of function if particular nerve is injured
Define and under stand terms neuritis, anesthesia, par aesthesia,
paralysis, neuralgia, sciatica
34. LCM 1 Ang 34 SUPERFICIAL VESSELS AND LYMPHATICS OF LOWER LIMB
Enumerate and describe the superficial arteries of lower limb

Name and discuss superficial veins of lower limb
List and discuss the superficial lymphatic vessels and lymph nodes of
lower limb
35. LCM 1 Ang 35 DEEP FASCIA OF THIGH, ILIOTIBIALTRACT AND SAPHENOUS OPENING
Describe the arrangement of deep fascia in thigh and how the iliotibial
tract participates in walking and running
Describe the location of saphenous opening and its relations
Discuss clinical application of the topic
36. LCM 1 Ang 36 MUSCLES OF THE ANTERIOR FASCIAL COMPARTMENT OF THIGH
Discuss the concept of muscles of anterior compartment of thigh.

Describe the nerve supply of anterior compartment.
Describe the action of these muscles.
167
37. LCM 1 Ang 37 NERVES AND VESSELS OF ANTERIOR COMPARTMENT OF THIGH
Discuss the nerve supply of the anterior compartment of thigh.

Describe the blood supply and the venous drainage of anterior
compartment of thigh.
38. LCM 1 Ang 38 THE MEDIAL COMPARTMENT OF THIGH
Discuss the muscles of medial compartment of the thigh.

Discuss the blood & nerve supply of these muscles.
Describe the actions of the muscles of medial compartment of thigh
39. LCM 1 Ang 39 POSTERIOR COMPARTMENT OF THIGH
Describe the muscles of posterior compartment of thigh

Describe the arterial supply of posterior comparmentr of thigh
Disscuss the trochanteric and cruciate anastomosis at the back of thigh
Describe the venous drainage of this region
Describe the nerve supply of posterior compartment of thigh and
Relate to the clinical conditions effecting the region
40. LCM 1 Ang 40 POPLITEAL FOSSA
Describe the boundaries of popliteal fossa.

Describe the contents of the popliteal fossa.
Discuss some clinical correlates regarding popliteal fossa
41. LCM 1 Ang 41 FEMORAL SHEATH AND FEMORAL RING AND ADDUCTOR CANAL---
FEMORAL TRIANGLE AND ITS CONTENTS
Describe the location & boundaries of femoral triangle

List the contents of femoral triangle
Describe the femoral sheath & canal
Discuss the location, boundaries and contents of adductor canal
42. LCM 1 Ang 42 GLUTEAL REGION
Describe the location of gluteal region

Discuss bones and ligaments of gluteal region
Discuss about the different structures entering and leaving gluteal region
Describe muscles, vessels and nerves of gluteal region
Discuss about certain clinical correlates regarding gluteal region
168
43. LCM 1 Ang 43 THE HIP JOINT AND MOVEMENTS
Discuss the characteristics features of synovial joint

Describe the Articular surfaces of hip joint
Identify the the capsule of hip joint
Describe the synovial membrane, cavity & fluid of hip joint
Enumerate the ligaments of hip joint & describe their attachments
Discuss the movements possible at hip joint
44. LCM 1 Ang 44 TIBIA BONE
Describe the division of tibia bone in 3 parts

Identify the surfaces and borders of tibia
Decsribe the attachments of muscles on the tibia bone
Discuss the ossification of tibia and its primary and secondary
ossification centers
45. LCM 1 Ang 45 FIBULA & BONES OF FOOT
Determine the side of bone.

Describe the bony features along with its different attachments on the
fibula.
Name and describe the tarsal bones and their arrangment.
Name and describe the metatarsal bones and phalangeal bones.
46. LCM 1 Ang 46 ANTERIOR AND LATERAL COMPARTMENT OF LEG

Classify the compartments of leg
State the muscles of anterior and lateral compartment of leg
Describe the vessels of anterior and lateral compartment of leg
Describe the nerves of lateral and anterior compartment of leg
47. LCM 1 Ang 47 POSTERIOR COMPARTMENT OF LEG

Explain the concept of organization of the muscles of posterior
compartment of leg.
Describe nerve supply of these muscles.
Explain the actions of the muscles of posterior compartment of leg.
48. LCM 1 Ang 48 KNEE JOINT

Discuss the classification of knee joint
Describe the articular surfaces of this joint
Discuss the articular capsule
Describe the synovial membrane and the synovial cavity
Enumerate the ligaments of knee joint
Describe the bursa around the knee joint
Describe the blood and nerve supply of the knee joint
169
49. LCM 1 Ang 49 THE MUSCLES AND NEUROVASCULAR SUPPLY OF THE FOOT
Describe the dorsal muscles of foot.

Describe the origin and insertion of planter muscles of foot.
Describe their nerve supply and actions.
Describe vascular and nervous supply of sole and dorsum of foot
Describe their course through foot
Discuss relationships
50. LCM 1 Ang 50 ANKLE JOINT SUPERIOR & INFERIOR TIBIOFIBULAR JOINTS SUB-TALAR &
TRANSVERSE TARSAL JOINTS
Describe the Ankle Joint

Describe the Superior and Inferior Tibio-Fibular Joints
Describe Sub-talar Joint
Describe transverse tarsal joint or mid-tarsal joint.
51. LCM 1 Ang 51ARCHES OF FOOT

Describe the arches of foot and the factors responsible for their
maintenance
Recognize the injury when it occurs and be able to evaluate plantar
fasciitis.
Discuss about counselling regarding the rehabilitation for plantar
fasciitis.
52. LCM 1 Ang 52SURFACE ANATOMY OF LOWER LIMB
Demostrate the surface anatomy of arteries of lower limb.

Demostrate the surface anatomy of superficial & deep veins lower limb.
Demonstrate the surface anatomy of nerves of lower limb.
EMBRYOLOGY
1. LCM 1 Ane 1DEVELOPMENT OF MESODERM, PARAXIAL MESODERM AND

SCLEROMYOTOME AND FORMATION OF CARTILAGES
Define the process of gastrulation.
Describe the development of mesoderm.
Describe the process of somitogenesis.
Describe the formation of cartilage.
170
2. LCM 1 Ane 2 DEVELOPMENT OF BONE , CARTILAGE AND JOINTS
Discuss histogenesis of Bone

Describe the Intramembranous Ossification
Describe the Endochondral Ossification
Describe the Ossification of limb bones
Describe the development of joints
Describe the development of cartilage
3. LCM 1 Ane 3 DEVELOPMENT OF LIMBS
Describe the early stages of limb development

Discuss the development of upper and lower limb buds
Describe the final stages of limb development
Describe and explain the anomalies of the limbs
4. LCM 1 Ane 4 DEVELOPMENT OF MUSCLES
Describe the development of skeletal muscle.

Discuss the development of Myotomes and derivatives of epaxial
divisions of myotomes and derivatives of hypaxial divisions of myotomes
5. LCM 1 Ane 5 HISTOLOGY & DEVELOPMENT OF MAMMARY GLANDS
Describe breast development in puberty & in the adult

Describe histology of mammary gland in non-lactating, lactating & during
pregnancy
Identify and describe the nipple and areola
Describe the histologic changes in breasts during pregnancy & lactation
Describe the postlactational regression of the breasts
Discuss about cancer of the breast
Discuss the medical application
HISTOLOGY
6. LCM 1 Anh 1 CLASSIFICATION & HISTOLOGY OF CARTILAGE
The General properties of cartilage

Different types of cartilage
Properties and ocations Hyaline, Elastic and Fibrocartilage
Growth of cartilage
171
7. LCM 1 Anh 2 HISTOLOGY OF CARTILAGE
Identify types of cartilages at the light and electron microscope levels,

including distinctive features of each.
Describe the structural basis.
8. LCM 1 Anh 3 CLASSIFICATION & HISTOLOGY OF BONE
Recognize bone and its functions and composition.

Differentiate between woven bone and lamellar bone.
Differentiate between compact bone and spongy bone.
Discuss the applied aspect of bone
9. LCM 1 Anh 4 HISTOLOGY OF BONE
Identify three types of bone at the light and electron microscope levels,
including distinctive features of each.
Describe the structural basis.
10. LCM 1 Anh 5 HISTOLOGY OF MUSCLES
Identify three types of muscle at the light and electron microscope

levels, including distinctive features of each muscle fiber.
Describe the structural basis of muscle striations.
Regognize the structural elements that produces muscle contraction and
brings the movement of a body part.
Recognize the function and organization of the connective tissue in
muscle.
PHYSIOLOGY
1. LCM 1 Phy 1 ELECTRICAL PROPERTIES OF NEURON
Describe the basic structure and function of neuron
State its basic physical and electrical properties of neuron
Explain the factors on which the resting membrane potential depends
Explain the mechanics of action potential initiation and measurements of
action potentials.
Describe the basics of patch-clamp technique
2. LCM 1 Phy 2INITIATION AND PROPAGATION OF ACTION POTENTIAL
Define some basic electrophysiological terms

Discuss post synaptic potentials (PSPs)
Discuss of Resting Membrane Potential (RMP)
Define Ionic equilibrium Potential
172
Define Action Potential
State the key properties of Action potentials
Describe the phases of Action Potentials
Describe the characteristics of Action Potentials
3. LCM 1 Phy 3FUNCTIONAL CLASSIFICATION OF NERVE FIBER

Define nerve fiber
Describe basic functional anatomy of a nerve fiber
Classify nerve fiber
Explain the conduction of Action Potentials
4. LCM 1 Phy 4 SYNAPTIC TRANSMISSION
Classify different types of synapses

Classify the types of synaptic transmission
Explain the steps involved in chemical transmission
Classify the neurotransmitters and its types
Explain summation and classify its types
Explain Neuromuscular transmission and classify its types
5. LCM 1 Phy 5 PAIN PATHWAY & ADAPTATION
Name the types of peripheral nerve fibers and receptor types that
mediate nociception.
Explain the difference between pain and nociception.
Explain the differences between fast and slow pain and acute and
chronic pain.
Explain hyperalgesia and allodynia.
Describe and explain referred pain.
6. LCM 1 Phy 6 NCV AND EMG(NERVE CONDUTION VELOCITIES AND

(ELECTROMYOGRAPHY)
Define the principles of NCVs and EMGs

State the purpose of advising these tests
Describe how the NCVs and EMG are carried out
7. LCM 1 Phy 7 THE MUSCULAR TWITCH RESPONSE AND RECRUITMENT (PRACTICAL)

Record and measure the muscular twitch response to nerve stimulation,
and show recruitment in the twitch response as the stimulus strength
increases
173
8. LCM 1 Phy 8SUMMATION AND TETANIZATION
Measure the effects of changing the interval between paired stimulus
pulses
Observe a short tetanic contraction
9. LCM 1 Phy 9FATIGUE (PRACTICAL)

Measure the decline in maximal force during a sustained contraction .
Examine some properties of muscular fatigue .
10. LCM 1 Phy 10 DISORDERS OF NMT
Explain the mechanism of NMT

Describe the role of neurotransmitter
Discuss the diseases that affect NMT
State the chemical agents that affect NMT
11. LCM 1 Phy 11 PROPERTIES OF MUSCLE FIBERS
Classify the types of muscle fibers.

State the properties of muscle fibers.
Explain the functions of muscles.
Describe the Stimulus and properties of stimuli.
Describe the effects of multiple stimuli on muscle fibers.
Describe the properties of smooth muscle and cardiac muscle fiber.
12. LCM 1 Phy 12 MECHANISM OF SKELETAL MUSCLE CONTRACTION DIFFERENTIATE BASIS

OF SMOOTH MUSCLE CONTRACTION
Classify the types of muscle tissue
State their functional characteristics
Describe the structural organization of skeletal muscle
Describe the Ultrastructure of Sarcomere
Explain the mechanism of muscle contraction
Describe the excitation/contraction sequence
Explain the sliding filament theory
Explain the process of Relaxation
13. LCM 1 Phy 13 MUSCLE METABOLIC ADAPTATION TO EXERCISE
Explain skeletal muscle metabolic adaptations to exercise

Classify types of muscle fibers
Describe the distribution and recruitment of different muscle fibers
Explain the muscle metabolic adaptations to exercise (acute and chronic)
Explain the recovery from exercise-EPOC
Recognize the Health Advantages of Regular Exercise
174
14. LCM 1 Phy 14 ELECTROMYOGRAPHY(PRACTICAL)
Employ the basic practical approach towards EMG, spontaneous activity,

motor unit potentials, recruitment and interference patterns, single fiber
EMG, pitfalls and cautions.
15. LCM 1 Phy 15 PHYSIOLOGY OF LACTATION
Describe the Anatomy of mammary gland,

Explain the Physiology of mammary gland
Describe the Lactation reflex
Describe the Hormonal effect
16. LCM 1 Phy 16 INTRODUCTION TO THE POWER LAB AND LAB TUTOR
Recognize the major hardware and software components of the lab tutor
system
Setup a powerlab and apply it on data acquisition, analysis and report
formulation on various lab tutor experiments
BIOCHEMISTRY
1. LCM 1 Bio 1 BIOCHEMISTRY OF CARTILAGE
Eneumerate the functions of cartilage.

Describe the biochemical composition of Cartilage in general
Discuss the composition of Extra-cellular matrix {Glycosaminoglycan
(GAG)}
Relate degenerative conditions associated with disturbances in the
normal composition.
2. LCM 1 Bio 2 BIOCHEMISTRY OF BONES AND THE ROLE OF HORMONES IN MODELING

AND REMODELING
Describe the chemical composition of bone

Explain the role of osteoblasts and osteoclasts cells in bone
mineralization and bone resorption
Define Rickets, Osteomalacia, Osteoporosis, Osteogenesis imperfecta
3. LCM 1 Bio 3 BIOCHEMISTRY OF BONES AND THE ROLE OF HORMONES IN MODELING

AND REMODELING
Describe and Explain the role of Parathyroid Hormones, calcitonin + Vit-
D in Bone Modeling and remodeling.
175
4. LCM 1 Bio 3 CHEMISTRY OF NEUROTRANSMITTERS
Define neurotransmitters
Enlist the neurotransmitter of locomotor system. Give their structure.
Enlist different neurotransmitter receptors
Describe the synthesis of these neurotransmitters.
State and explain that acetylcholine has sympathetic & parasympathetic
functions.
Explain the mechanism of action of acetylcholine in modulating muscle
contraction.
PATHOLOGY
1. LCM 1 Pth 1 VITAMIN D DEFICIENCY STATES
Define Vitamin D
Explain significance of vitamin D in the body
Describe the different deficency states related with vitamin D
Discuss the prevention of Vitamin D Deficiency
2. LCM 1 Pth 2 TYPES AND IMPORTANT CLINICAL MANIFESTATIONS OF OSTEOPOROSIS
Define of osteoporosis
Describe generalized and localized osteoporosis
List the primary and secondary causes of generalized osteoporosis
Define Pathogenesis and clinical course
Discuss its complications and management
3. LCM 1 Pth 3 FRACTURES AND BONE REPAIR
Define terms related to fracture: Stress Fracture, Incomplete fracture,

Closed (simple fracture), Open (complicated) fracture, multifragmented
fractures, complex fracture, Pathologic fractures
Describe mechanism of bone healing
Enlist complications of fracture
Describe etiology & Pathogenesis of Pathologic fracture
4. LCM 1 Pth 4 JOINT INFLAMMATION TYPES OF ARTHRITIS (OSTEOARTHRITIS) OA I
Define Osteoarthritis?
Explain pathophysiology of osteoarthritis
Dsecribe the clinical features of osteoarthritis
5. LCM 1 Pth 5 JOINT INFLAMMATION TYPES OF ARTHRITIS (RHEUMATOID ARTHRITIS)

RA II
176
Enlist types & classification of various forms of arthritis.
Define rheumatoid arthritis
Describe etiology & risk factors, pathogenesis, & complications
6. LCM 1 Pth 6 PATHOPHYSIOLOGY OF BONE INFECTION (OSTEOMYELITIS)
Classify different types of osteomyelitis

List factors leading to their etiology
Explain its pathogenesis
Discuss its complications and management
Enumerate clinical features, make diagnosis & know the criteria
Enlist differential diagnosis.
7. LCM 1 Pth 7 NON NEOPLASTIC DISEASES OF THE BREAST
Discuss the etiology/pathologic features of different forms of benign

non-neoplastic and neoplastic breast disease.
Discuss the benign breast diseases that increase a patients risk of
developing breast cancer and
Classify these conditions by the degree of risk
Outline other risk factors predisposing to breast
Cite the cancer & incidence/prevalence of breast cancer.
8. LCM 1 Pth 8 NEOPLASTIC DISEASES OF THE BREAST
Name the Neoplastic lesions of the breast.

Name & briefly describe the Benign Epithelial lesions of the breast.
Classify the histological types & give brief description of Carcinoma of
the Breast
Name & briefly describe the male breast lesions.
PHARMACOLOGY
1. LCM 1 Pha 1 CALCIUM AND VITAMIN D PREPARATIONS
Recognize various calcium preparations, their chemical
formulations and mode of administration
2. LCM 1 Pha 2 DRUGS USED IN OSTEOPOROSIS
List the drugs used in the treatment of osteoporosis

Explain their mode of action
Explain their pharmakokinetics
State the ide effects of these drugs
177
3. LCM 1 Pha 3 DRUGS USED FOR ARTHRITIS (ACETAMINOPHEN)
Enlist known therapies for RA

Explain MOA and adverse effects of NSAIDS
Explain MOA and Adverse Effects of Acetaminophen
4. LCM 1 Pha 4 DRUGS USED IN ARTHRITIS NSAIDS (ASPIRIN)
Describe their general properties.

Classify the drugs
Explain the mechanism of action.
State their actions in general.
Discuss their clinical uses.
Explain the pharmacokinetics and dynamics of different NSAIDs,
including COX-2 selective NSAIDs
Describe general properties.
Describe aspirin toxicity.
Describe drug interactions.
Discuss clinical application.
State the contraindications
COMMUNITY MEDICINE
1. LCM 1 Com 1 EPIDEMIOLOGIC STUDY DESIGN
Recognize concepts of different study designs

Apply the knowledge of study design in research projects
Classify different study designs
Recognize the advantages and disadvantages of several study designs
2. LCM 1 Com 2 THE NORMAL DISTRIBUTION CURVE AND Z-SCORES
Define properties of the normal curve.

Describe mean and standard deviation of the normal curve.
Define area under the curve.
Calculate z-scores.
3. LCM 1 Com 3 CONFIDENCE INTERVAL AND STANDARD ERROR
Describe confidence interval and standard error

Differentiate advantage of confidence interval over point estimate
4. LCM 1 Com 4 HEALTH TRANSITION
Define epidemiologic transition/health transition.
178
Describe epidemiologic & demographic transition in developing
countries.
Explain double burden of diseases.
Enlist causes of Epidemiologic transition.
Discuss available NCD data in Pakistan.
5. LCM 1 Com 5 INJURY VIOLENCE AND ACCIDENT
Define injury
Enumerate types of injuries.
Define accident.
Define intentional injuries.
Define unintentional injuries.
Define traffic injuries.
Define home accidents.
Define drowning.
Define injury prevention.
6. LCM 1 Com 6 DISASTER MANAGEMENT

Classify and define disaster and types of disaster
Explain pre disaster management
Explain pre disaster administration
Identify pre disaster planning
Identify social reactions followed by disaster
Understand the surveillance cycle of a disaster
Define bio terrorism
7. LCM 1 Com 7 HEALTH PROMOTION & EDUCATION

Describe the stages of health education.
Explain the strategies of health education.
8. LCM 1 Com 8 ELDERLY HEALTH
Define geriatrics
Describe magnitude of problems of aging populations .
Identify human resources for health care of the elderly.
Cite Epidemiology on elderly population problems.
List solutions of elderly problems.
BEHAVIORAL SCIENCES
1. LCM 1 Beh 1 MEDICAL ETHICS:
Describe concept of Ethical Dilemmas in the life of doctor

Describe the consequences of Ethical Omission in medical practice
Define Branches of ethical medical professionalism and Pillars of Medical
ethics.
179
Describe concept of ethics in light of Hippocratic Oath
Describe the importance of Ethics in the life of a doctor
Describe the different components of Ethical professionalism
Enumerate characteristics of Ethical Professionalism
Apply concept of medical ethics and professionalism in different clinical
setting
2. LCM 1 Beh 2 COMMON ETHICAL OMISSIONS IN MEDICAL PRACTICE
Describe the importance of Informed consent and confidentiality

Describe the procedure of taking informed consent and maintaining
confidentiality
Apply given concepts in different clinical setting and different settings
related to Medical
RADIOLOGY
1. LCM 1 Rad 1 NORMALX RAYS OF UPPER LIMB
Recognize the basic radiological anatomy of upper limb
Relate imaging with gross anatomy
Identify the bones and joints on x-ray
Know the different views of the x- ray
Recognize imaging vocabulary
2. LCM Rad 2 CROSS SECTION OF UPPER LIMB
Identify the anatomic structures of upper limbs on standard radiographic
and cross sectional images
3. LCM 1 Rad 3 NORMAL X RAYS OF LOWER LIMB
Recognize little Basics of Imaging

Relate imaging with Gross anatomy
Identify the bones and joints on X-ray
Recognize the different views of the X- ray
Develop imaging vocabulary
4. LCM 1 Rad 4 CROSS SECTIONAL ANATOMY OF LOWER LIMB
Interpret Cross sectional anatomy of lower limb
Interpret the cross sectional anatomy on various advance imaging modality
Identify the bones and joints on CT and MRI
Read and Interpret sectional anatomy of lower limbs on CT and MRI
180
ORTHOPAEDIC
1. LCM 1 Ort 1 FRACTURES & DISLOCATIONS OF THE UPPER LIMB
Understand the mechanisms and forces which results in fracture and dislocation
of bones of upper limb.
Know the common types of fractures of bones of upper limb and areas involved.
Understand the basic principals of management of common fractures.
Understand how to reduce common dislocations and their postoperative
management.
2. LCM 1 Ort 2 SOFT TISSUE DISORDERS UPPER LIMB
Understand different inflammatory and soft tissue disorders of upper limb

Understand the basic principles of management of these disorders
3. LCM 1 Ort 3 FRACTURES & DISLOCATIONS OF THE LOWER LIMB
Describe and clinically co-relate to:
Dislocation of hip
Fracture of Neck of Femur
Injuries of mid thigh
Fracture of shaft of femur.
Injuries of lower thigh and knee
Condylar or supra condylar femur fracture.
Dislocation of knee.
Injuries of upper end of leg.
Fracture of upper end of tibia.(Bumper Fracture)
Injuries of mid leg
Fracture of tibia and fibula
Injuries of lower leg and ankle.
Potts fracture.
Sprain ankle.
Dislocation ankle.
Injuries of foot.
Fracture of calcaneus
LCM 1 Ort 4 DEFORMITIES OF LOWER LIMB
Describe and clinically co-relate to:
CONGENITAL DEFORMITIES:
Wrist - Madelung's deformity.
Hand - syndactylism, poly dactylism
Congenital deformities of lower limbs:
Congenital talipus equino varus (club foot)
Congenital dislocation of hip
181
Congenital genu recurvatum, genu varus (bow knees)
Congenital pseudoarthrosis of tibia (bow legs)
Acquired deformities:
The most common causes of acquired deformities are;
Trauma
Infection
Degeneration
Tumor
Metabolic disorder
4. LCM 1 Ort 5 JOINT DISORDERS/ ARTHRITIS
Joint disorders
Definition of arthritis
history ,examination aspect of arthritis
Different types of arthritis
Investigations required for diagnosing different types of arthritis
NEUROLOGY
1. LCM 1 Neur 1 EXAMINATION OF THE UPPER LIMB NERVES
Describe the sensory and motor nerve supplies of the different regions of Upper
limb
Perform examination of nerves of Upper limb
Apply knowledge of lesions of different nerves of Upperlimb and what
abnormality would appear in case of a lesion
2. LCM 1 Neur 2 EXAMINATION OF NERVES OF LOWER LIMB
Describe the sensory and motor nerve supplies of the different regions of lower
limb
Perform examination of nerves of lower limb
Apply knowledge of lesions of different nerves of lower limb and what
abnormality would appear in case of a lesion
3. LCM 1 Neur 3 CLINICAL PRESENTATIONS OF NEUROMUSCULAR DISEASE
Recognize different patterns of presentation of neuromuscular disorders on

basis of history and examination
Describe different varieties of muscle, neuromuscular junction, peripheral
nerve, root and anterior horn cell disorders
Enumerate investigations for these disorders including EMG, NCV, muscle
enzymes
VASCULAR SURGERY
1. LCM 1 Vas 1 APPLIED ANATOMY OF UPPER AND LOWER LIMB BLOOD VESSELS
182
Revise main arterial and venous supply of upper limb
Apply injuries or disease associated with vessels of upper limb
Revise main arterial and venous supply of lower limb
Apply injuries or disease associated with vessels of lower limb
CASE BASED LEARNING

1. CBL 1
Recognize the causes of weakness in the limb.
Identify modalities of investigation of muscular disorders.
Recognize the genetic basis of muscle diseases.
Understand the finding of Electrophysiology (EMG / NCVs).
2. CBL 2
Anatomy of the axilla.
Anatomy of the breast and relationship to the axilla
Clinical importance of axilla in relation to breast diseases
3. CBL 3
Identify the normal structures related to elbow joint
Relate the changes that may occur due to fracture in this area
Identify radiological anatomy of upper limb
Recognize that injury to one structure is not isolated but also involves other
adjacent structures
4. CBL 4
Know the normal structures of the elbow region
Know the neurovascular relations of the elbow joint
Know the common injury patterns of this region
Differentiate the various neurovascular injuries at the elbow
5. CBL 5
Understand Course of major vessels in the thigh.
Correlate Blood loss which can be associated with gun shot injury.
Understand Clinical assessment of nerves of lower limb.
Understand that an injury at thigh can damage various tissues locally and can be
associated with systemic complications
6. CBL 6
Know the motor and sensory distribution of lumbar nerve roots.
Recognize the features that occur due to disease of a certain nerve root.
Correlate the motor and sensory impairment to identify the level of nerve root
involved.
183
ORTHO 1: Locomotion Module:
I. VITAL SIGNS:
INTRODUCTION/RATIONALE:
This is one of the first skills that a healthcare professional needs when dealing with patients
generally and specially in suspected cases of shock due to injuries. Accurate measurement of
vital signs is of prime importance in the decision making process of diagnosis and
management. Students will watch demonstration videos and then practice the measurement of
five vital signs.
The module is divided into two sub modules and will be taught in two sessions.
Module 2A- Temperature, Pulse, Respiration and Pain
Module 2B- Measuring Blood Pressure
After The Sessions The Student Should Be Able To:
Demonstrate the correct methods of assessing Vital Signs.
Demonstrate effective communication skills during and after assessment.
Sub Topic Learning Objectives
TEMPERATURE
1. Identify different types of thermometer
2. List the four sites for assessing temperature and Recognize expected differences
between the measurements obtained at different sites.
3. Demonstrate how to take oral temperature and read the thermometer accurately.
PULSE
4. Identify seven sites where pulse may be counted ( Superficial Temporal radial,
carotid, femoral, popliteal, posterior tibial, dorsalis pedis)
5. Demonstrate correct palpation of radial pulse, count the pulse rate and note its rhythm
accurately.
6. Describe method of assessing pulse in infants (heart rate in neonates and brachial pulse
in infants)
RESPIRATORY RATE
7. Demonstrate how to count and record respiratory rate accurately
PAIN
8. Demonstrate the ability to use a pain measurement scale (faces pain scale, visual
analog scale) to evaluate the intensity of patient's pain.
9. Demonstrate the ability to empathize with the patient in pain
184
BLOOD PRESSURE:
10. Identify the different parts of the instruments (stethoscope and sphygmomanometer)
and their types.
11. Demonstrate proper placement of BP cuff on the arm and thigh.
12. Demonstrate how to measure and record blood pressure accurately
13. Describe and demonstrate the methods used to assess blood pressure in different
pediatric age groups.
14. Demonstrate appropriate communication skills before, during and after the procedure.
II. Basic life Support:

Rationale:
The skills learned in this class will enable students to recognize emergencies
such as sudden cardiac arrest &know how to respond to them, as cardiac arrest
is a leading cause of death worldwide.
At the end of the session student should be able to
1. Demonstrate the basic steps of CPR for adults & infants
185
WEEK 1st 2nd 3rd 4th 5th 6th 7th 8th TOTAL Round of %
Credit
hours
GROSS 8.5 5.5 9 9.5 8.5 18.5 15.5 7.5 82.5 46.4 4.9
46
ANAT. (3.0) (0.06)
EMBR 1 3 1 5 2.81
3 0.31
HISTO 2.5 1.5 2.5 1.5 8 4.50 0.21

5
(4.5) (0.09)
PHYSIO 5 3.5 6.5 1.5 1.5 1.5 19.5 10.9 0.65
11
(9.0) (0.18)
BIOCHEM 3 1.5 1.5 6 3.38 0.28
3
(1.5) (0.03)
PHARM 2 4.5 1 7.5 4.22
4 0.46
PATHO 1 4 2 1 8 4.50 5 0.5
COM.MED 1 1 1 1.5 2 1 1 8.5 4.78

5 0.53
BEH.SCI 1 1 2 1.12 1 0.12
RES.METH 1.5 1.5 0.84

1 0.09
SKILLS 1.5 1.5 1.5 1.5 6 3.38

3 0.38
ORT 1 2 2 5 2.81
3 0.31
RAD 2 2.5 4.5 2.53

3 0.28
NEURO 1 2.5 3.5 1.97

2 0.21
VASC SRG 1 1 0.56

0.06
CBL 1.5 1.5 1.5 1.5 1.5 1.5 9 5.07

5 0.56
TOTAL 17 27.5 26.5 22.5 16 26 21 21 177.5 99.77

100 10.21
186
LOCOMOTOR MODULE
(SEMESTER II)
SUMMATIVE ASSESMENT
THEORY

SEMESTER
EXAM
ATP 25 80%
PAPER-I
One best Questions
20
based on CBL
Total 100
MODULE EXAM
EMQs 10
ATP 20
MODULE PAPER 20%
One best Questions
20
based on CBL
Total 100
STRUCTURED VIVA

SUMMATIV
ASSESME
SEMESTE
R EXAM
See Semester
NT
PAPER-IV- A Structured viva

E
Assessment Plan
ASSESMENT TOOLS
Structured Feedback
Facilitator
NOTE: Paper II & IV-B of Semester 2 Examination are Based on Respiraton Module.
Paper III & IV-C of Semester 2 Examination are Based on Cardiovacular Module.
187
CREDIT HOURS
SEMESTER II
LOCOMOTOR MODULE
I 6
Locomotion
IV A 3
188
Respiratory Module
(RSP 1)
Semester II
First Year MBBS
189
Spiral Sem. Modules

I Physiology, Biochemistry, Microbiology, Antimicrobials &Neoplasia
II
Spiral Bones, Joints, Nerves & Muscles, 8 Week System 4 wks System4Week
III NEU1-Nervous System HNN1- Head & END1- Endocrinology

8 weeks Neck&Special 4 weeks
4 Week
diseases 4 week 4 week System4week System4 week
wks
Second th
Spiral th
Trauma, 6 week
3 week 8 Weeks
VIII ENT Rheumatology & Dermatology Genetics 8 Weeks
3 wk Rehabilitation 2 Plastic Surger 1 wk
/ Burns 2 wk
Weeks
th
th
PARALLEL THEMES:
190
MODULE COMMITTEE
Prof. FouziaImtiaz, Professor of Biochemistry, DIMC

Prof. NighatRukhsana, Professor of Physiology, DIMC (Focal Person)
Prof. ShaheenSharafat, Professor of Pathology, DIMC
Dr. Syed Samiullah, Assistant Professor of Anatomy, DIMC
Dr. Noor Kamil, Assistant Professor of Pharmacology, DIMC
Dr. Faisal FaiyazZuberi, Assistant Professor of Pulmonology, OICD, DUHS
Dr. NaveeduzZafar, Assistant Professor of Pathology, SMC
Documented by:
Dr. Mohammad ArsalanSiddiqui
Dr. Ateeba Ayesha Khan
Coordinated by:
Dr. SabahatZaidi
Reviewed by:
Modular committee
191
Rationale:
A doctor in Clinical Practice will comeacross a large number of patients who have
disorders related to respiratory system as In our community there is ahigh prevalence
of respiratory diseases particularly in children where the leading cause of morbidity
and mortality in children is ARI and pneumonia.To be able to manage these, the basis
of oxygen administration and artificial ventilation should be taught in earlier years.
The understanding of air flow dynamics will enable the student to understand the
diseases like asthma, chronic bronchitis and their remedies. At the same time the
diseases related to smoking like lung cancer and chronic bronchitis are also on the rise
and a firm understanding of the respiratory system will enable the student to prevent
such lifestyle diseases through spreading relevant health education messages. The
student training should also include mechanism and uses of inhalers.
Terminal Objectives:
By the end of respiratory module the students will be able to:
1. Describe the normal and abnormal structures and functions of respiratory system.
2. Interpret the biochemical changes in the body related to the respiratory system with
reference of some common respiratory disorders.
3. Describe normal changes that occur in respiratory system functioning from infancy to
old age.
4. Elaborate the pathophysiology and types of infective respiratory disorders
5. Explain obstructive and restrictive pathologies involving respiratory system
6. Identify role of respiratory system in controlling acid-base balance
7. Take history and perform a satisfactory physical examination of the respiratory
system.
8. Formulate an appropriate plan for evaluating patients with respiratory signs and
symptoms to achieve a reasonable differential diagnosis.
192
Objectives of module are listed in following grid along with contents,

Modes of information Transfer, duration of teaching of each content and the
mode of assessment.
Lectures
Demo:
Tutorials
Practical
CBL / SBL
Self Study
spotting
Practical /
One Best,
Skills Lab
EMQS
viva
Objectives
Assesment
Modes of information transfer
ANATOMY RSP 1 Ang 1 Overview of 1
Thorax
1. Overview the
(Skeleton, wall, Outlet, inlet)
* *
components of
Thoracic Cavity and
PHYSIOLOGY RSP 1 Phy 1 Functional 1.5
their relations.
organization of respiratory
* *
system +innervation
EMBRYOLOGY RSP 1 Ane1Development of 1
ribs & vertebrae
* *
1
RSP 1 Ang 2Gross Features of * *
sternum
RSP 1 Ang 3Gross Features of 1
2. Identify the role Thoracic vertebrae
* *
of thoracic skeleton
in respiration. ANATOMY
RSP 1 Ang 4 General 1.5
Features + attachment of
* *
typical Ribs
RSP 1 Ang 5 General Features 1.5

+ attachment of Atypical Ribs
* *
3. Describe Larynx HISTOLOGY RSP 1 Anh 1Respiratory 1
and associated epithelium
* * *
structures in ANATOMY 1
relation to defense, * *
phonation and RSP 1 Anh 2Larynx
cough mechanism. HISTOLOGY 1.5
Enlist the clinical * * *
conditions related RSP 1 Anh 3
to its disorders. Larynx & Trachea.
EMBRYOLOGY RSP 1 Ane2Development of 1

4. Explain the respiratory system&
* *
developmental and Developmental anomalies
structural anatomy
BIOCHEMISTRY RSP 1 Bio 1 Classification of 1.5
related to
Compound Lipids and
* *
respiratory system
biochemical importance of
and associated
Lecithins in respiration
anomalies.
CBL RSP 1 CBLRespiratory Distress 1.5
Syndrome (RDS)
* *
193
Lectures
Demo:
Tutorials
Practical
CBL / SBL
Self Study
spotting
Practical /
One Best,
Skills Lab
EMQS
viva
Objectives
Assesment
Be able to diagnose, COMMUNITY RSP 1 Com 1Effects of 1.5
manage and counsel MEDICINE smoking on community
* *
patients whose
respiratory
disorders are caused
by social,
occupational,
environmental
factors.
RSP 1 Ang 6 Thoracic cavity 1.5
division & boundaries of
* *
mediastinum&Joints of
thoracic cage
5. Explain RSP 1Ang7 Thoracic muscles, 1.5
Respiration in ANATOMY Inter costal spaces
* *
relation to
RSP 1Ang 8Diaphragm 1.5
a. Anatomical * *
movements RSP 1Ang 9Thoracic 1
b. Physiological Movements with respiration
* *
mechanisms (including involvement of
c. Biochemical abdominal wall)
changes
RSP 1 Phy 2 Mechanics of 1
respiration
* *
PHYSIOLOGY 1.5
RSP 1 Phy 3 Respiratory rate * * *
with the help of-- Power lab&
breath holding effect
EMBRYOLOGY RSP 1Ane3Development of 1
Body Cavities
* *
RSP 1RadThoracic inlet 1
RADIOLOGY Relations & Cross sectional
Anatomy
PHYSIOLOGY 1.5
RSP 1Phy 4 Group, A, B, C : * *
Physiology Practical: Normal
& rapid Breathing
RSP 1Ang10 1.5
6. Get recognition
with the thoracic Superior mediastinum and its
* *
cavity development, contents
divisions and
relations of
constituent
1.5
structures.
RSP 1Ang 11 Contents of * *
ANATOMY anterior Mediastinum +
Posterior Mediastinum
RSP 1Ang12Thoracic 1.5

sympathetic trunk,
* *
Phrenic and vagus nerve,
Thoracic duct.
RSP 1 Ang 13 Anatomy Demo 1
Pleura + Gross anatomy of
* *
Lungs
194
Lectures
Demo:
Tutorials
Practical
CBL / SBL
Self Study
spotting
Practical /
One Best,
Skills Lab
EMQS
viva
Objectives
Assesment
RSP 1Ang 14 vasculature of 1
Lungs- bronchial &pulmonary
* *
+ Lymphatic
of thorax
HISTOLOGY 1.5
RSP 1Anh 4 * *
respiratory epithelium
CLINICAL RSP 1 Med 1 Clinical 1
FACULTY Examination of respiratory
* *
System
CBL: 1.5
RSP 1 CBLChest injury * *
PHYSIOLOGY RSP 1 Phy5 Lung volume and 1.5
capacities + PFTs
* *
CLINICAL 1
FACULTY RSP 1 Lab 1Clinical * *
Applications of PFTs
7. Recognize the
importance of lung SKILLS LAB AND 1.5
volumes and DIGITAL LAB
RSP 1 SklAuscultation of the * *
capacities for lungs
breathing and PHYSIOLOGY RSP 1Phy6Lung Vol& 1.5
diagnosis of Capacities (Practical)
* *
disorders.
RADIOLOGY RSP 1 Rad 2Radiology Normal 1.5
respiratory structure on chest
* *
radiograph.
structures making right & left
heart borders Identify nasal
structures on radiography
1
RSP 1 Phy7Lung Compliance * *
1
RSP 1 Phy8Pulmonary
circulation
* *
V/Q RELATIONSHIP
1.5
PHYSIOLOGY RSP 1Phy 9 * *
Diffusion of gases
RSP 1Phy 10 Transport of 1
8. Discuss the
Gases:
* *
mechanism of
Transport of O2 and O2-Hb
gaseous exchange,
dissociation curve
transport and role in
RSP 1 Phy 11 Transport of 1.5
metabolism.
CO2 in relation to physiology
* *
RSP 1Bio 2 1
Role of respiration in
* *
glycolysis, CO2 and H2O
BIOCHEMISTRY production
RSP 1 Bio 3Electron Transport 1.5
Chain& biological oxidation
* *
RSP 1 Bio4 Role of 1
Bicarbonate and electrolytes
* *
for normal gaseous exchange.
195
Lectures
Demo:
Tutorials
Practical
CBL / SBL
Self Study
spotting
Practical /
One Best,
Skills Lab
EMQS
viva
Objectives
Assesment
PHYSIOLOGY RSP 1 Phy12Regulation of 1.5
respiration (Chemical &
* *
Neural)
PHYSIOLOGY RSP 1Phy 13 Hypoxia & its 1.5
types
* *
CBL: RSP 1 CblPulmonary 1.5
Embolism
* *
9. Compare regular RSP 1 Phy 14 Respiratory 1
breathing adjustment to exercise, high
* *
acclimatization in altitude and deep sea
normal and PHYSIOLOGY 1.5
abnormal body RSP 1 Phy15Effect of re- * *
states. breathing on the respiratory
rate and Pulse rate.
CLINICAL RSP 1 Med 2Recognize the 1.5
MEDICINE signs and symptoms of
* *
common respiratory
disorders
ANATOMY RSP 1 Ang15 1.5
10. Recognize the Surface anatomy
* *
common signs and CLINICAL 1.5
symptoms of Medicine RSP 1 Med 6PFTs
* *
respiratory
COMMUNITY 1.5
disorders like cough,
MEDICINE
RSP 1 Com 2 Asthma * *
hemoptysis, SOB, RSP 1 Com 3 Tuberculosis 1.5
etc. * *
CLINICAL RSP 1 Med 6ABGs
Medicine interpretation
* *
1
RSP 1 Bio5 Role of respiratory * *
system for Acid base Balance
BIOCHEMISTRY
11. Enlist and RADIOLOGY RSP 1 Rad 3Radiology and 1
Explain disorders of Imaging of Respiratory
* *
respiratory system: System
RDS, Pulmonary 1
embolism, Chest RSP 1 Pth 1ARDS * *
injuries, COPD / PATHOLOGY
1
Asthma RSP 1Pth 2 COPD; Its types,
pathogenesis and clinical
* *
features.
Bronchitis & its pathogenesis
CBL: 1.5
RSP CblCOPD / Asthma * *
RSP 1Pth 3 Asthma, 1.5
pathogenesis, clinical
* *
manifestation.
Bronchiectasis, its etiology
PATHOLOGY and pathogenesis of
1
* *
RSP 1 Pth 4 Pleural Effusion
&Pneumo thorax
196
Lectures
Demo:
Tutorials
Practical
CBL / SBL
Self Study
spotting
Practical /
One Best,
Skills Lab
EMQS
viva
Objectives
Assesment
RSP 1Pth 5 Pulmonary 1.5
Vascular Disorders
* *
Define pulmonary embolism,
RSP 1 Pth 6Lung Cancer 1

* *
1
RSP 1Pth 7Tuberculosis
* *
RSP 1 Pth 8Classification of 1.5
Pneumonia
* *
RSP 1 Pth 9 Microscopic 1.5
stages of pneumonia
* *
(Practical)
13. Enumerate the PATHOLOGY
important and
common disorders RSP 1 1.5
of the respiratory Pth10Histopathology/Micros
* *
tract. cpy of Tuberculosis (Practical)
(Enlistcommon
infections related to
upper & lower
RSP 1 Mic1Common 1
respiratory tract
pathogens causing
* *
(URI, LRI))
community acquired
pneumonia
RSP 1 Mic2Mycobacterium 1
Microbiology
Tuberculosis
* *
RSP 1 Mic3Zeihl Nelson 1.5

Staining
* *
RSP 1 Pha 1 Introduction of 1.5

goals of therapy of Asthma
* *
Major component of long &
short term asthma
manAngement
Brief description of
complementary & alternative
Describe the basic
PHARMACOLOGY therapies for asthma
management of the
RSP 1 Pha 2 Introduction of 1
respiratory
goals of therapy of COPD,
* *
disorders
Major component of long &
short term manAngement,
brief description of
complementary & alternative
therapies.
RSP 1 Pha 3Drugs used for 1

* *
197
Lectures
Demo:
Tutorials
Practical
CBL / SBL
Self Study
spotting
Practical /
One Best,
Skills Lab
EMQS
viva
Objectives
Assesment
Community Acquired
Pneumonia(Penicillin)
RSP 1 Pha 4Drugs used for 1
Community Acquired
* *
Pneumonia(Macrolides+Quin
olones)
RSP 1 Pha 5Anti-Tuberculosis 1
therapy (1+2)
* *
198
EMESTER II, RESPIRATION MODULE
TIME TABLEWEEK 1
DAYS 8:30 to 9:30 9:30 to 10:30 11.00 to 12.30 1:30 to 3.00

Anatomy Anatomy
Overview of General description Physiology Anatomy Demo
Thorax of upper respiratory Functional organization of General Features + attachment of
(Skeleton, wall, Tract & Lower respiratory system typical Ribs+
DAY 1
Outlet inlet) Respiratory Tract + innervation A+B+C= FACULTY
FACULTY FACULTY FACULTY VENUE D+E= FACULTY -1
VENUE NIGAR VENUE
1.A=Biochemistry
Chemistry of inflammatory
mediators in respiratory
disordersVENUE
FACULTY R. ATIF
2.B=SELF STUDY
Anatomy 3.C= Histology Practical-
Histology Respiratory Epithelium+
Anatomy Demo
Respiratory Anatomy Demo: trachea + FACULTY General Features + attachment of
DAY 2 Epithelium+ Sternum- FACULTYVENUE Atypical Ribs
histology of larynx FACULTY 3.D= CBL of last week of A+B+C= FACULTY IALH
and trachea VENUE locomotion D+E= FACULTY VENUE
FACULTY
VENUE 4.E= Physiology Practical:
Introduction to Power
labwith respect to respiration
DR. MEHWISH / DR.
ANWAR
VENUE
Anatomy 1. B=DR. ATIF

CM
General features of vertebra+ 2. C
DAY 3 Acute respiratory track
Curvatures of vertebral column. 3. D
infection
A+B+C= FACULTY ALH 4. E
FACULTY VENUE
D+E= FACULTY VENUE 5. A
Anatomy Demo 1. C= DR. DANISH

Thoracic vertebrae 2. D
DAY 4
(typical + atypical) 3. E
A+B+C= FACULTY ALH 4. A
D+E= FACULTY VENUE 5. B
Anatomy 1. D= DR. DANISH

Anatomy
Thoracic muscles, Inter costal spaces 2. E
DAY 5 Diaphragm (thoracic Outlet)
Wall 3. A
A+B+C= FACULTY ALH
FACULTY N 4. B
D+E= FACULTY VENUE
VENUE 5. C
199
SEMESTER II RESPIRATION MODULE
TIME TABLE WEEK2
DAYS 8:30 to 9:30 9:30 to 10:30 11.00 to 12.30 1:30 to 3.00

LAST WEEK PRACTICAL
1.E=Biochemistry Chemistry of
inflammatory mediators in respiratory
Anatomy disorders VENUEFACULTY
Thoracic 2.A=SELF STUDY Anatomy
Physiology
Movement with Thoracic Cavity , Division &
Mechanics of 3.B= Histology Practical-Respiratory
DAY respiration Boundaries of Media stinum& Joints
respiration Epithelium+ trachea +lungs
1 (including of thoracic cage
FACULTY FACULTYVENUE
involvement of A+B+C= FACULTY VENUE
VENUE 3.C= CBL of last week of
abdominal wall D+E= FACULTY
FACULTY locomotion
4.D= Physiology Practical:
VENUE Introduction to Power labwith
respect to respirationDR. MEHWISH /
DR. ANWAR VENUE
Thoracic inlet Superior mediastinum and its contents
Anatomy Demo (Arch of aorta,ligamentumarteriosum,
Relations & Cross Anatomy
DAY Pleura
sectional Gross + Histology of Lungs Brachiocephalic vein,Superior vena
2 FACULTY cava, Cardiac plexus,Trachea)
Anatomy FACULTY VENUE
VENUE A+B+C= DR. SABHATVENUE
FACULTY
VENUE D+E= FACULTY
1.A=CBL
2.B= SKILL LAB Auscultation of
lung Anatomy Demo
DAY Physiology Anatomy 3.C= PHYSIOPRACT : Recording of Contents of anterior
3 vasculature of normal respiratory rate and Mediastinum (Thymus) + Posterior
Lung Compliance
Lungs- bronchial & relationship b/w respiratory rate and Mediastinum (Thoracic Aorta,
FACULTY pulmonary pulse rate OesophagusAzygous System
VENUE FACULTY KHAN FACULTY PHYSIO. LAB A+B+C= FACULTY VENUE
VENUE 4.D= SELF STUDY D+E= FACULTY
5.E= Histology Practical
Lungs FACULTY
DAY
4
PATHOLOGY 10:00-
DAY 1. C
Define asthma, pathogenesis, 10:30
2. D
5 clinical manifestation, Define AM
3. E
bronchiectasis, its etiology and SELF
4. A
pathogenesis ofbronchiectasis STUD
5. B
FACULTY VENUE Y
DAY Pharmacology Anatomy 1. D

Physiology
Drugs used in Development of ribs 2. E
6 Pulmonary volume and capacities
Asthma and COPD-1 & vertebrae 3. A
FACULTY FACULTY 4. B FACULTY VENUE
VENUE NVENUE 5. C VENUE
200
SEMESTER IIRESPIRATION MODULE
WEEK- 3TIME TABLE
DAYS 8:30 to 9:30 9:30 to 10:30 11.00 to 12.30 1:30 to 3.00

Last week practical
1. E
Pathology
2. A Clinical faculty
DAY 1 Chronic Obstructive pulmonary disease
3. B Pulmonary function test
Describe pathogenesis of bronchitis
4. C FACULTY VENUE
FACULTY VENUE 5. D
FACULTY
ANATOMY
Pharmacology Histology of Last week practical
Drugs used in alveolar capillary 1. B
Asthma and membrane+ general 2. C Physiology
DAY 2
COPD II + description of tissue 3. D diffusion of gases
ANTITUSSIVES arrangement in 4. E FACULTY VENUE
FACULTY hollow viscera 5. A
VENUE FACULTY FACULTY
VENUE
1 A=Pathologypractical:microscopic
images of asthma,
Emphysema,bronchitis&bronchiactesis.
DR. SAIMA RASHID
PATHO LAB
Pathology 2 B= Physiology Practical: effects of
Physiology Pulmonary rebreathing on respiratory rate and
Pulmonary pulse rate.VENUE. FACULTY CM
Vascular Disorders
circulation Effects of smoking on the
DAY 3 (pulmonary 3 C= CBL
V/Q Community
embolism
RELATIONSHIP + V/Q Scan) 4 D= PHARMA TUTORIAL Approach FACULTY
FACULTY in treatment of Bronchial asthma + VENUE
VENUE FACULTY Methods of administration of Drugs:
VENUE
Nebulization, etc.)
PHARMA LAB
FACULTY
5 E= SKILL LAB Auscultation of
lungSKILL LAB
Physiology
transport of Gases Biochemistry 1. B
(O2-Hb Role of respiration 2. C Physiology
DAY 4
dissociation in glycolysis, CO2 3. D transport of CO2 in relation to physiology
curve) and H2O 4. E FACULTY VENUE
FACULTY production 5. A
VENUE
DAY 5
Biochemistry
1. D
Role Of Buffers In Physiology
10:00-10:30 2. E
DAY 6 Hydrogen Ion Homeostasis Hypoxia & its types
am 3. A
FACULTY Self-study FACULTY VENUE
VENUE 4. B
5. C
201
SEMESTER II RESPIRATION MODULE
TIME TABLE -WK 4
DAYS 8:30 to 9:30 9:30 to 10:30 11.00 to 12:30 1.30 to 3.00
Biochemistry Pharmacology LAST WEEK PRACTICAL

Role of Respiratory Drugs used in 1. C Physiology regulation of respiration
DAY 1 system for Acid Asthma and COPD 2. D CHEMICAL + NEURAL
base balance, (ANTITUSSIVES) 3. E
FACULTY VENUE
FACULTY FACULTY 4. A
VENUE VENUE 5. B
Biochemistry Physiology LAST WEEK PRACTICAL

Electron transport Respiratory
chain & biological 1. E Biochemistry
DAY 2 adjustment to 2. A
oxidation exercise,high altitude Metabolism of Phospholipids and its role in
3. B ARDS
FACULTY and deep sea 4. C
VENUE FACULTY 5. D
FACULTY VENUE
VENUE
Anatomy
Development of
Anatomy:
respiratory system
Pathology Thoracic sympathetic trunk, CM
DAY 3 & Developmental
ARDS Phrenic and vagus nerve, Thoracic ASTHMA, risk factors,prevention and control
anomalies of
FACULTY duct. FACULTY VENUE
respiratory System
VENUE FACULTY VENUE
FACULTY
VENUE
1A= Pathology
practical:microscopic stages of
PATHOLOGY
pneumoniaDR. SAIMA
Classification of Anatomy
PNEUMONIA 10:00- 2B=Physiology Practical :Lung
DAY 4 10:30AM Vol&Capacities +PFT Lymphatic of thorax
CommacqtypicalpneuComm A+B= FACULTY VENUE
acqatypical pneu SELF DR. MEHWISH/ DR. ANWAR
STUDY C+D= FACULTY VENUE
Aspiration pneumonia 3C= CBL
FACULTY VENUE E= FACULTY VENUE
4D= SELF STUDY
5E= SELF STUDY
Pharmacology Microbiology
Drugs used for Common Pathogens 1. B
community acquired causing Community 2. C
DAY 5 Acquired Pneumonias
pneumonia 3. D
1.Penicillin (typical and atypical) 4. E
VENUE VENUE
PATHOLOGY Pharmacology 1. C Clinical faculty

SA6 Pleural effusion 2.Macrolides 2. D ABG'S
22/6 Pneumothorax 3.Qunolones 3. E
Lab investigations and interpretation for
respiratory status
VENUE VENUE 5. B
VENUE
202
SEMESTER II -RESPIRATION MODULE
TIME TABLE WEEK 5
DAYS 8:30 to 9:30 9:30 to 10:30 11.00 to 12:30 1.30 to 3.00
Last week practical

PATHOLOGY Pharmacology
1. D
Pleural effusion 2.Macrolides
DAY 1 2. E
Pneumothorax 3.Qunolones SELF STUDY
3. A
FACULTY FACULTY
VENUE VENUE 4. B
5. C
Last week practical
PATHOLOGY 1. C Clinical faculty

Microbiology
Mycobacterium Pathology of 2. D ABG'S
DAY 2 Tuberculosis Lab investigations and interpretation for
Tuberculosis 3. E
FACULTY FACULTY respiratory status FACULTY VENUE
VENUE 4. A
VENUE
5. B
Community Last week practical

Pharmacology
Medicine 1. E Radiology
ATT 1: Tuberculosis
DAY 3 AntiTuberculous 2. A
FACULTY
drugs 3. B Normal respiratory structure on chest radiograph.
VENUE
FACULTY 4. C FACULTY
VENUE VENUE
5. D
1.A+B+C= Histopathology
practical Microscopy of TB Anatomy
Radiology Pharmacology 5 Groups Demo
CT scan FACULTY
ATT 2: VENUE Surface Anatomy of thorax
DAY 4 FACULTY AntiTuberculous A + B = FACULTY VENUE
VENUE drugs C + D= FACULTY VENUE
FACULTY 2.D+E= Microbiology Zeihl E= FACULTY
VENUE Nelson staining
FACULTY
Pathology Clinical Faculty 1. D+ E

Signs & symptoms of
Ca lung
respiratory disorders
DAY 5 FACULTY And Clinical
VENUE
Examination of 2. A+B+C
respiratory System
FACULTY
DAY 6
SELF STUDY
203
At The End Of The Lecture The Student Should Be Able To
GROSS ANATOMY
RSP 1 Ang 1Overview of Thorax (Skeleton, wall, Outlet inlet)

Describe the structural outline of thorax
Enlist the different components of thoracic cage
Identify the different compartments of thoracic cavity
Describe the boundaries of thoracic inlet and outlet
RSP 1 Ang 2Gross Features of sternum

Describe the location and shape of the sternum
Describe the parts of the sternum
Describe the articulations and muscle attachments
Discuss the relations and clinical importance
Correlate to applied anatomy
RSP 1 Ang 3Gross Features of Thoracic vertebrae

Describe the gross features of the thoracic vertebrae; vertebral
body, IV disk, Laminae, pedicles, intervertebral foramina, processes
and important ligaments.
RSP 1 Ang 4General Features + attachment of typical Ribs

Classify the ribs.
Identify the different parts of typical rib.
Discuss the features of typical ribs.
RSP 1 Ang 5General Features + attachment of Atypical Ribs

List and identify the different parts of atypical rib.
Discuss the features of atypical ribs.
RSP 1 Ang 6Thoracic cavity division, boundaries of mediastinum

&Joints of thoracic cage
Classify and list the joints of thorax
Identify the structures of the thoracic cavity
Discuss the division and boundaries of mediastinum
204
RSP 1Ang7Thoracic muscles, Inter costal spaces
Identify the different layers of thoracic walls
Identify Intercostal muscles
Discuss about the contents of intercostal spaces
Describe &Explain the origin of intercostal arteries
Describe &Explain the origin, course and distribution of intercostal
nerves
Discuss about the branches and course of internal thoracic artery
Clinically correlate to the thoracic wall& its abnormalities
RSP 1Ang 8Diaphragm

Describe the origin and insertion of the diaphragm
Describe the openings of the diaphragm
Explain its actions
Discuss the clinical correlates
RSP 1Ang 9 Thoracic

Movements with respiration (including involvement of
abdominal wall)
About principles of respiratory movement
Movements involved to change diameter of thoracic cage
Movement in different phases of respiration, both under normal
and stressed condition
RSP 1 Ang10 Superior mediastinum and its contents

Enlist and describe the contents of the superior mediatinum
Describe the relations of its contents
Describe blood & nerve supply of the vicera
Discuss clinical correlates
RSP 1 Ang 11 Contents of anterior Mediastinum (Thymus) + Posterior

Mediastinum
Enlist and describe the contents of the Anterior & Posterior
Mediatinum
Describe blood & nerve supply of the viscera
205
RSP 1 Ang12Thoracic sympathetic trunk, phrenic and vagus nerve, Thoracic
duct.
RSP 1 Ang 13Anatomy Demo Pleura + Gross anatomy of Lungs

Describe the gross features of pleura
Describe the pleural cavity and the pleural reflections
Outline the surface anatomy related to pleural reflections
Discuss the clinical application related to the topic
Explain the gross description of lung with relation to its borders and
surfaces
Describe the detailed structure of right and left lungs and the
difference between them
Describe & Explain the bronco pulmonary segments and their
importance
Discuss about the nerve supply to lungs , pulmonary plexus and the
importance of phrenic nerve
RSP 1Ang 14vasculature of Lungs bronchial & pulmonary

Describe the route and alternative roles of the two vascular
system that permeate lung tissue
RSP 1 Ang 15Surface anatomy

Out line the surface anatomy of the thorax
EMBRYOLOGY
RSP 1 Ane 1Development of ribs & vertebrae
Discuss the stages of development of the vertebral column
Discuss the development of ribs from costal elements of
primitive vertebrae
Clinically correlate to associated congenital anomalies including
spina bifida, spondylolisthesis, scoliosis, kyphosis, extra rib, fused
rib and pigeon shaped chest.
206
RSP 1 Ane2Development of respiratory system& Developmental anomalies of
respiratory System
Enumerate the different Parts of Respiratory System
Name the Different Parts of Foregut
Discuss the formation of laryngo- tracheal tube
Discuss the formation of Lung Bud
Describe the Branches of Bronchi
Discuss the different Stages of development of Lung
Describe Maturation of Lung
Clinically correlate to the congenital errors during development
RSP 1Ane 3Development of Body Cavities

Identify the intra embryonic mesoderm and its parts
State the division of lateral plate mesoderm into visceral and
parietal layers enclosing intra embryonic caelome or body cavity
Recognize the cephalo-caudal and transverse foldings of embryonic
disc
Describe the extent of intra embryonic coelom after folding and its
divisions into three serous cavities
State the derivatives of visceral and parietal layers of mesoderm
State the pericardio-peritoneal canals and their final fate
Explain the development of diaphragm from various tissue sources
Clinically correlate to the main anomalies related to body cavities
and diaphragm
HISTOLOGY
RSP 1 Anh 1respiratory epithelium

Describe the structural details of respiratory system
Classify the types of epithelia lining the various parts of respiratory
system
Differentiate between the histological differences among various
parts of respiratory system
Recognize &Identifythe individual structures in H& E and EM
sections.
207
RSP 1 Anh 2Larynx
Describe the different layers of larynx

Discuss the histological characteristics of each layer of larynx
Describe the histological classification of laryngeal cartilage
RSP 1 Anh 3Larynx &Trachea

Describe the structure of trachea and its layer
Describe the different layers of trachea and their histological
characteristics
RSP 1Anh 4Respiratory Epithelium,Alveolar capillary membrane

& general description of tissue arrangement in the hollow viscera
(Practical)
Describe the microscopic anatomy of respiratory bronchiole.
Discuss the microscopic picture of alveolar ducts, alveolar sacs and
alveoli.
Know the different types of cells found in respiratory tract like type
1 and type2 cells found in alveoli
Discuss surfactant, alveolar septum, alveolar pores and alveolar
macrophages
Describe blood-air barrier.
Discuss the clinical aspects related to the topic.
PHYSIOLOGY
RSP 1 Phy 1Functional organization of respiratory system
Different phases of respiration
Respiration occurring at different levels in the human body
Classification of respiratory system according to structure and
function
Describe the structure and functions of nasal cavity, pharynx,
larynx, trachea, bronchi, bronchioles and alveoli
RSP 1 Phy 2Mechanics of respiration

Define and explain internal and external respiration
Define gas laws of respiratory physiology
Describe the role of pressure gradients in causing air to flow in
and out of the lungs
208
Explain the role of respiratory muscles in producing pressure
gradients
Explain the relevance of pulmonary compliance and elasticity
to ventilation
Define various measurements of pulmonary function
RSP 1 Phy 3Respiratory rate with the help of-- Power lab&breath holding effect
Record breathing movements
Investigate various aspects of breathing (Breath holding ability,
hyperventilation and re-breathing)
Determine the relationship between breathing and heart rate
RSP 1Phy 4Group, A, B, C: Physiology Practical: Normal & rapid Breathing

Describe the respiratory pattern of normal and rapid breathing
Investigate the relationship between breathing and heart rate
RSP 1 Phy 5Lung Volume & Capacities + PFTs& individual variability

Describe the parameters of Pulmonary Function Tests
Explain the pattern of PFTs in obstructive and restrictive disease
Differentiate between obstructive and restrictive diseases on the
basis of PFTs
RSP 1 Phy 6Lung volume and capacities + PFTs (Practical)

Explain the principles of spirometry and how integration of the flow
signal gives a volume.
Relate your recorded lung volumes and capacities, to those of a
typical person of the same gender, height and age.
Perform pulmonary function tests, describe the common
measurements made from them (PIF, PEF, FVC and FEV1) and relate
these measurements to those of a typical person of the same
gender, height and age.
Describe the effect of airway restrictions on PIF, PEF, FVC and FEV1.
RSP 1 Phy 7Lung Compliance

Define Lung compliance
Explain compliance diagram of lungs
209
Explain how do lungs adapt and why?
Explain tension on lung surface
Explain lung and chest compliance
Define laplace law
RSP 1 Phy 8Pulmonary circulation V/Q RELATIONSHIP
Explain the mechanism of blood flow to lungs

Describe & Explain the regional distribution of ventilation and
perfusion due to effect of gravity in lungs
Explain the concept of physiological shunt
Explain the concept of physiological dead space
Illustrate Ventilation perfusion ratio in different parts of lungs in
health and disease
State the partial pressures of oxygen and carbondioxide in
physiological shunt and dead space
RSP 1Phy 9Diffusion of gases

Describe the gas exchange process
Mixed Gases and Partial Pressure
Explain the physiologic principles of Gas Exchange
Explain the mechanisms of Gas Movement
Explain the Bulk flow principles
Define the gas Laws, diffusion coefficient, diffusion capacity
State the factors affecting rate of diffusion
RSP 1Phy 10Transport of O2 and O2-Hb dissociation curve

Explain the steps of gas exchange in lungs and tissue
Describe the process of oxygen diffusion
Explain the transport of oxygen in blood.
State the influence of oxygen on haemoglobin saturation.
Describe the role of haemoglobinin oxygen transport.
Explain the O2-Hb dissociation curve.
Describe the factors affecting on O2-Hb dissociation curve.
RSP 1 Phy 11Transport of CO2 in relation to physiology
Differentiate the 3 ways of CO2 transportation.

Describe the transport and exchange of CO2 in blood.
210
Describe the transport and exchange of CO2 in tissue.
Describe the transport and exchange of CO2 in lungs.
Explain the influences of CO2 on blood pH.
RSP 1 Phy 12Regulation of respiration (CHEMICAL & Neural)
Discuss control of breathing

Explain how blood gases affect the respiratory center of brain?
Explain how respiratory center control blood gases and pH?
Discuss Nervous regulation (autonomic control).
Explain how brain stem regulates respiration
Describe and explain the other stimuli that modify the respiratory
rhythm and the pathways that these signals take to the brain stem.
Describe voluntary control (cerebral cortex)
RSP 1Phy 13Hypoxia& its types

Define Hypoxia.
Describe the Hypoxic injury to cell.
Explain the types of Hypoxia.
Elucidate the causes of hypoxia
Describe Cyanosis
Discuss the Effects of Hypoxia
RSP 1 Phy 14Respiratory adjustment to exercise, high altitude and deep sea
Explain the respiratory responses in relation to exercise
Describe and Explain the changes occurring in the muscles during
exercise
Discuss the response of Oxygen hemoglobin dissociation curve
during exercise
Discuss about oxygen debt and its importance
Explain how does the respiratory system adapt to high altitude
pressures
Discuss acclimatization and its importance
Clinically correlate to under water diving and changes in the body
Describe & Explain decompression sickness and its consequences
211
RSP 1 Phy 15Effect of re-breathing on the respiratory rate and Pulse rate.
Describe and explain the effects on the respiratory pattern of re-
breathing expired gas
Describe and explain the relationship between breathing and heart
rate
BIOCHEMISTRY
RSP 1 Bio 1Classification

of Compound Lipids and biochemical importance of
Lecithins in respiration
Discuss the synthesis of phospholipids
Discuss the metabolism of phopholipids
Discuss the synthesis of surfactant
Discuss the role of pneumocytes
Discuss the lecithin/ sphingomyelin ratio in relation to respiratory
distress syndrome
RSP 1Bio 2 Role of respiration in glycolysis, CO2 and H2O production

Define cellular respiration
Identify the key players and stages of cellular respiration
Describe and explain the steps of glycolysis
Correlate with other biochemical pathways
RSP 1 Bio 3Electron Transport Chain& Biological oxidation

Compare the mitochondrial content of different tissues and relate this
characteristic to the function of the particular tissue
Describe the purpose of the electron transport chain (particularly
complexes I, III, and IV) and ATP synthase, their substrates and
products, their cellular localization, and their tissue distribution
Explain how electron transport and ATP synthase are functionally
coupled
Explain how the process of oxidative phosphorylation is influenced by
the availability of oxygen and NADH
Explain how the cellular ATP:ADP ratio regulates the rate of ATP
production by oxidative phosphorylation
Discuss biological oxidation
Name the enzymes involved
212
Explain various biochemical reactions
Correlate with various biochemical cycles
RSP 1 Bio 4Role of bicarbonate and electrolytes for normal gaseous exchange
Explain the normal physiology of serum electrolytes
Explain different biochemical abnormalities
Explain the roles of electrolytes in gaseous exchange
RSP 1 Bio5Role of respiratory system for Acid base Balance

Define acid base balance
Define acidosis
Discuss the significance & source of hydrogen ions
Describe the types of acidosis
Discuss respiratory acidosis in detail
Define alkalosis
Discuss the significance & source of bicarbonate ions
Describe the types of alkalosis
Discuss respiratory alkalosis in detail
PATHOLOGY
RSP 1 Pth 1ARDS
Define Acute Lung Injury and ARDS

Describe the causes of ARDS
Discuss the characteristic features, morphology and pathogenesis of
ARDS
Describe its consequences and clinical course
RSP 1 Pth2COPD; Its types, pathogenesis and clinical features

Define chronic obstructive lung diseases (COPD)
Classify the types of COPD
Discuss their common features
Identify the causes, underlying patho-physiology, morphology, and
clinical features of chronic bronchitis
213
RSP 1 Pth3Asthma & Bronchiectasis; Pathogenesis & clinical manifestations
Describe the etiology of asthma& Bronchiectasis
Describe its signs & symptoms
Describe the diagnostic tests
Describe its management
RSP 1 Pth4Pleural Effusion &Pneumo thorax

Enlist the lesions of the pleura
Define pleural effusion and state its causes
Classify and explain different types of pleural effusions
Define pneumo-thorax and state its causes
RSP 1Pth 5Pulmonary Vascular Disorders
Describe the pathophysiologic response, clinical significance and

consequences of pulmonary embolism
Describe features, clinical course and sign and symptoms of
pulmonary embolism
State the diagnostic tests for pulmonary embolism
Describe the features of pulmonary infarction
Define pulmonary hypertension
Describe its groups, pathogenesis, morphological features, clinical
course, sign and symptoms and diagnostic strategies
Define diffuse pulmonary hemorrhagic syndromes.
Describe the features of Good pasture syndrome, Idiopathic
pulmonary hemosiderosis and Wegener granulomatosis
RSP 1 Pth6Lung Cancer
Describe its epidemiology
State its risk factors
Classify different forms of lung cancers
Define and illustrate with examples paraneoplastic syndrome
Describe the staging system
214
RSP 1 Pth7Tuberculosis
State it etiology
Recogize the communicable granulomatous disease caused by
mycobacterium tuberculosis
Discuss its epidemiology
Explain the pathogenesis of Granuloma formation
Recognize and describe the five different clinical patterns of
tuberculosis
Define primary and secondary tuberculosis
Describe physical examination, laboratory & radiological
findings
Describe and explain its complications
RSP 1 Pth 8Classification of Pneumonia
Define pneumonia
Discuss the etiological classification of pneumonia
Discuss its clinical presentation
Describe the diagnostic tools for pneumonia
RSP 1 Pth 9 Microscopic stages of pneumonia (Practical)
Identify histopathologic changes in pneumonia under a microscope

Identify the causative organism
Describe the various stages under a microscope
RSP 1 Pth10Histopathology/Microscopy of Tuberculosis (Practical)
Recognize the use of zeihl nelson staining in its identification

Identify histopathologic changes in tuberculosis under a microscope
Describe the various stages under a microscope
MICROBIOLOGY
RSP 1 Pth1Common pathogens causing community acquired pneumonia
Define pneumonia
Discuss the etiological classification of pneumonia
Describe the features of some important causative organisms of
pneumonia
Describe the diagnostic tools for pneumonia
215
RSP 1 Pth2Mycobacterium Tuberculosis
Classify Mycobacterium associated with human disease
State the transmission
Describe its clinical presentation
Discuss its management
RSP 1 Pth3Zeihl Nelson Staining

Describe the process of Zeihl Nelson staining
Describe its positive appearance
Discuss its clinical application
PHARMACOLOGY
RSP 1 Pha 1Asthma
Recognize the goals of therapy of Asthma

Explain the major component of long & short term asthma
management
Explain the mechanism of action, route of administration and adverse
effects of first line agents
Describe thecomplementary& alternative therapies for asthma
RSP 1 Pha 2COPD
Recognize the goals of therapy of COPD

Explain the major component of management based on severity
effects of first line agents
Describe the complementary & alternative therapies
RSP 1 Pha3Drugs used for Community Acquired Pneumonia(Penicillin)

Name the common infectious causes of pneumonia
Name the antibiotics used for the treatment
effects
Discuss the drug interactions
216
RSP 1 Pha 4Drugs
used for Community Acquired Pneumonia
(Macrolides+Quinolones)
effects
Discuss the pharmaco-kinetics
RSP 1 Pha 5Anti-Tuberculosis therapy (1+2)

Name the antibiotics used for the treatment
effects
COMMUNITY MEDICINE
RSP 1 Com 1Effects of smoking on community
Describe the history of Tobacco Smoking.

Describe chemical constituents of Tobacco.
Describe habits of Tobacco Smoking.
Explain health effects of Tobacco smoking
Discuss the tobacco production in Pakistan.
Describe tobacco control program.
Discuss tobacco free initiative.
RSP 1 Com 2Asthma
Define Asthma
Discuss the global burden of Asthma
Explain the etiology, triggers and clinical manifestation
Describe its management
RSP 1 Com 3Tuberculosis
Describe how TB is diagnosed.

Describe the treatment process for someone diagnosed with TB.
Describe how employees can monitor their own TB status.
Describe epidemiology of TB in terms oftime trends and geographical
variation and susceptible group
217
BEHAVIORAL SCIENCES
RSP 1BehHysterical Breathing, Functional Breathing
Define Hysterical and functional breathing

Explain its mechanism
Discuss its clinical implication
RADIOLOGY
RSP 1 Rad 1 Thoracic inlet Relations & Cross-sectional Anatomy
Describe different structures that can be identified on CT chest
Recognize different levels of mediastinal CT
Describe the appearance of lung parenchyma on CT chest
RSP 1 Rad 2Radiology
Recognize the normal respiratory structure on chest

radiograph.
Discuss the positions of the lobes.
Name structures making right & left heart borders
Identify nasal structures
RSP 1 Rad 3Radiology and Imaging of Respiratory System

Read a normal chest X-ray
Identify the main regions where a chest X-ray may show an
abnormality
Describe how different tissue appear on chest X-ray
MEDICINE
RSP 1 Med 1Clinical Applications of PFTs
Describe the parameters of Pulmonary Function Tests
Explain the pattern of PFTs in obstructive and restrictive disease
Differentiate between obstructive and restrictive diseases on the
basis of PFTs
218
RSP 1 Med 2Clinical Examination of the respiratory system
Enumerate the different signs elicited after a clinical examination of a
patient with respiratory disorders
The techniques of examination
Be able to correlate the findings with common diseases
RSP 1 Med 3Recognize the signs and symptoms of common respiratory disorders
Enumerate the various symptoms of respiratory disorders.
Correlate the symptoms with the signs of respiratory distress.
Determine the cause of respiratory distress in a patient with particular
sign or symptom
RSP 1 Med 4Clinical Applications of ABGs

Define Arterial Blood Gases (ABGs).
List the indication of ABG test.
Identify the samples for evaluation of respiratory status.
State the methods of transportation of sample for ABGs.
State the method & equipment for measuring ABGs.
Describe the parameters measured as arterial blood gases within their
normal ranges (pH, pCO2, HCO3, pO2).
Describe the steps to interpret ABGS.
Discuss the various results of ABGs.
Respiratory Module:
I. Introduction To Respiratory System Examination:
INTRODUCTION/RATIONALE: Diseases of respiratory system are one of the most

common causes of morbidity and mortality, both in adults and children. Respiratory system
examination is performed as an integral part of physical examination, or when a patient
presents with respiratory problems (for example: shortness of breath, cough or chest pain).
At the end of the session students should be:-
Familiar with the correct method of inspection, palpation and percussion of chest.
To demonstrate correct technique of auscultation of chest
219
CASE BASED LEARNING
CBL 1:
Define pneumonia ?
List the pathogens known to be causative agents of pneumonia?
Explain the pathogenic mechanism of pneumonia?
Describe the findings of lung consolidationand discus its clinical
implication?
Enlist the complications of pneumonia?
Describe the clinical course of pneumonia?
CBL 2:
To learn types & mechanisms of hypoxia
To learn common causes of sudden onset of Chest pain
To learn common causes of acute shortness of breath
To learn mechanism of hypoxia responsible for acute pulmonary
embolism
CBL 3:
Describe the major difference between obstructive and restrictive
lung pathology
Explain different lung capacities and volumes.
Interpret the effect of bronchodilators on lung volumes in a
obstructive scenario.
Describe different treatment options for the given pathology.
CBL 4:
Identify the patient having tuberculosis
Describe the pathophysiology of the given pathology
Interpret different types of tuberculosis
Define the management for the given scenario.
CBL 5:
Differentiate between obstructive and restrictive lung diseases.
Classify the stages of the given pathology
Describe the causes, symptoms and management for the given
pathology
Interpret the X-ray findings for the given scenario.
220
WEEK 1st 2nd 3rd 4th 5th 6th 7th 8th #Round
TOTAL *** of %for
PAPER1
Gross 6 - 3.25 4.5 3.5 5 1.75 - 14

ANAT. 24 13.85
EMBR - 1 3.5 3.75 2.75 3.5 3.75 4.75 23 13.27 13
HISTO 7.75 6.5 4.5 6.25 1.5 1.5 1.5 - 29.5 17.02 17
PHYSIO 6.5 1.5 - - - 1.75 - - 9.75 5.627 6
BIOCHE 1.5 3 4.75 4.75 6.5 6 1.5 - 16

M 28 16.16
PHARM - - - 2.75 3.75 5.5 1 6 19 10.96 11
PATHO 1 3.75 5.25 1.5 - 1 2.75 3.75 19 10.96 11
MICRO - 1 2.5 - - - 1 - 4.5 2.59 4
COM.M - 1.5 1 1 1 1.5 1 - 4

ED 7 4.04
BEH.SCI - - 1 - - - 1 - 2 1.15 1
RES.ME - - - 1.5 1.5 1.5 1.5 - 3

TH 6 3.46
SKILLS - - - - 1.5 - - - 1.5 0.86 -
Total 1 22.75 18.25 25.75 25.75 22 27.25 16.75 14.7 173.2 100 100
5 5
Total 2 - - - 1.5 1.5 1.5 1.5 - -
for III A
(CBL) 6 -
221
RESPIRATION MODULE
(SEMESTER II)
SUMMATIVE ASSESMENT
THEORY

SEMESTER
ATP 25
EXAM
PAPER-II One best Questions

20
based on CBL 80%
Total 100
MODULE EXAM
EMQs 10
ATP 20
MODULE PAPER 20%
One best Questions
20
based on CBL
Total 100
STRUCTURED VIVA

ASSESMENT
SUMMATIVE
SEMESTER
EXAM
See Semester
PAPER-IV- B Structured viva
Assessment Plan
ASSESMENT TOOLS
Structured Feedback
Facilitator
NOTE: Paper I & IV-A of Semester 2 Examination are Based on Locomotor Module.
Paper III & IV-C of Semester 2 Examination are Based on Cardiovacular Module.
222
CREDIT HOURS
SEMESTER II
RESPIRATION MODULE
II 3
RESPIRATION
IV B 1.5
223
CARDIOVASCULAR MODULE
Code: (CVS 1)
Semester: II
First Year MBBS
224
Spiral Sem. Modules

II

4 Week
wks
Second th
Spiral th
Trauma, 6 week
3 week 8 Weeks
/ Burns 2 wk
Weeks
th
th
PARALLEL THEMES:
225
MODULE COMMITTEE
1) Dr. Naheed Khan , Associate Professor of Anatomy

2) Dr. Mahmood Hassan, Professor of Pathology Focal person
3) Dr. KhalidaParveen, professor of Anatomy
4) Dr. NadeemAlam, Associate Professor of Biochemistry
5) Dr. KelashNankani, Associate Professor of Physiology
6) Dr. Abdul RaufMemon, Professor of Medicine
7) Dr. Muhammad Nawaz Lashari, Assistant Professor of Cardiology,
8) Dr. RukhsanaRubeen,Associate Professor of Biochemistry
Documented by:
DR SAIMA RASHID
Co-ordinated by
DR. SABAHAT ZAIDI
Reviewed by
Modular Committee
226
RATIONALE:
Cardiovascular diseases are common in the community and ischemic heart
disease is one of the most common noninfectiousdisease in our society.
Understanding of the structure and function cardiovascular system and their
relationship to diseases process is essential for diagnosis and management of
cardiovascular diseases.The cardiovascular module is designed to fulfill these
expectations.
TERMINAL OBJECTIVES:
Medical graduate after completion of 5 years training program should be able
to:
1. Recognize the clinical presentations of common cardiovascular diseases in

community.
2. Diagnose these diseases on the basis of history, examination and
investigations.
3. Explain pathological findings identified in cardiovascular pathology
4. Identify roll of pharmaceutical agents used for diseases involving
cardiovascular system.
5. Enlist clinical features of common cardiovascular pathologies
6. Interpret radiological investigations in relation to cvs.
7. Understand preventive measures for counseling their patients.
8. Practice basic principals of management of common diseases and make
appropriate referral
9. Aware of the prognosis to counsel their patients.
227
Lectures
Demo:
Tutorials
Practical
CBL / SBL
Self Study
Library
Digital
ATP
viva
Skills Lab
One Best, MCQS

OBJECTIVES FACULTY
TOPIC / CONTENT
Assessment
* *
CVS:1 Ang1 Overview of CVS 1
1 * *
CVS:1 Ang2 Overview of
Coronary blood vessels
CVS:1 Ang 3 Heart: covering * *

(pericardium) and external
Recognize the 1
features
normal structure of
heart including CVS:1 Ang4a Heart: Internal- * *
development, GROSS
ANATOMY features 1
topographical 1
anatomy, its blood * *
supply, nerve supply
and histology . CVS:1 Ang4 b Heart: Internal- 1
features 2
CVS1:Ang5 Conducting system, * *
Blood Supply, Nerve supply
1.5
CVS:1Ang 6 * * *
Heart, (surface marking of 1.5
heart and valves, great vessel
Histology CVS:1 Anh1 Histology of 1 * * *
Heart including myocardium
CVS1:Ang7 Anatomy Demo: 1.5 * *
Overview of principle arteries
Review the of body
arrangement of
arteries, veins, GROSS
CVS1:Ang8AnatomyDemo: 1.5 * *
lymphatics of entire ANATOMY
body Overview of principle veins of
body
228
Lectures
Demo:
Tutorials
Practical
CBL / SBL
Self Study
Library
Digital
ATP
viva
Skills Lab
One Best, MCQS

OBJECTIVES FACULTY
TOPIC / CONTENT
Assessment
CVS1:Ang 9 Anatomy 1.5 * *
overview of lymphatic channels
HISTOLOGY of body
CVS 1: Anh 2 Histology of blood 1.5 * * *
vessels
Identify the CVS1: Ane 1 Early Development 1.5 * - *

congenital of heart
anomalies of cvs including
CVS1: Anehistology
2 Late of
(asd, vsd, pda, tof, lymphatics of heart
Development
tga ) with reference EMBRYOLOGY
to normal CVS1: Ane 3
development and Development of Arterial
System
CVS1: Ane 4
early circulation
Development of Venous
System
CVS 1 : Phy 1 ARRHYTHMIAS * - *
Define functions of 1
cardiac muscle along CVS:1 Phy 2 Physiology 1.5 * *
with its properties ( Cardiac Cycle
infatiguability, non-
tetanization ) and CVS:1 Phy 3 * *
interpret PHYSIOLOGY Mechanism of cardiac muscle 1.5
mechanical/pressure contraction
changes during
CVS1: Phy 4 * *
cardiac cycle along
B.P auscultation and palpation 1
with regulation of
cardiac pumping. CVS:1,Phy:5 Excitation and 1.5 * *
conduction system of heart
CVS:1 Phy:6 ECG Basic * - *

Principals
Interpret normal & 1,5
abnormal ECG. ST-T * *
changes and its CVS:1 Phy:7
abnormalities in ECG Rate and Rhythm OF ECG 1.5
myocardial * *
PHYSIOLOGY
ischemia along with CVS:1 Phy:8
abnormalities of Vector Analysis of ECG 1.5
rhythm and block. CVS:1 Phy:9 * *
calculate heart rate. ECG and Heart sounds
1.5
* - *
CVS:1 Bio:1 Overview of 1.5
Identify the risk Lipid metabolism
229
Lectures
Demo:
Tutorials
Practical
CBL / SBL
Self Study
Library
Digital
ATP
viva
Skills Lab
One Best, MCQS

OBJECTIVES FACULTY
TOPIC / CONTENT
Assessment
factors and role of CVS:1 Bio:2 * *
lipids in Structure of fatty acids and 1
compound lipids related to CVS
CVS:1 Bio:3 =Calorimetry * *

1
BIOCHEMISTRY CVS:1 Bio:4 * *
Lipid Profile 1.5
CVS:1 Bio:5(a) * *
Chemistry synthesis and 1.5
functions of lipoproteins
CVS:1 Bio:5(b) * *
Chemistry synthesis and 1.5
functions of lipoproteins
CVS:1 Pth:1
Atherosclerosis
CVS:1 Pth:2(a) * *
Ischemic Heart Diseases 1 1
CVS:1 Pth:2(b) * *
Ischemic Heart Diseases 2 1
CVS-1: Pth: 2 ( c) (practical) * *

Histopathology Practical Slides 1.5
coronary blockage Of Atherosclerosis And IHD
and atherosclerosis ( CVS:1 Pha:2 Pharmacology * *
hyperlipidemia/ Lipid lowering drugs 1.5
dyslipidemia ).
CVS:1 Bio: 6 Oxidants and * *
antioxidants 1
CVS:1 Bio:7 Role of * *
Nutrition and antioxidants in
CVS Disorder. 1.5
CVS:1 Pha:1 Lipid Lowering 1
PHARMACOLOGY Drugs
Define cardiac * - *
output and factors PHYSIOLOGY 1
CVS:1 Phy:10 Cardiac output
modulating/
and its regulation
controlling COP.
Differentiate left
and right sided heart * *
failure and correlate PATHOLOGY CVS:1 Pth:3
it with the CARDIAC FAILURE 1.5
230
PATHOLOGY
Lectures
Demo:
Tutorials
Practical
CBL / SBL
Self Study
Library
Digital
ATP
viva
Skills Lab
One Best, MCQS

OBJECTIVES FACULTY
TOPIC / CONTENT
Assessment
importance of CVS:1 Pha:2
pressure differences Anti-Anginal Drugs
PHARMACOLOGY
.
CVS:1 Phy:11 * *
PHYSIOLOGY CVS adaptation during exercise 1
Name the common CVS:1 Pha:3a * *

cardiac arrhythmias. PHARMACOLOGY 1
describe the DRUGS USED IN ARRYTHMIAS
electrical events that
produce them. * *
PHARMACOLOGY CVS:1 Pha:3b 1
DRUGS USED IN ARRYTHMIAS
BEHAVIOURAL CVS:1 Beh :1

SCIENCES Crisis Intervention
Understand the * *
changes in CVS:1 Phy:12Hemo-dynamics
hemodynamics by 1
pulmonary
applying and
the (bloodflow,pressure,resistance)
knowledge of PHYSIOLOGY
systemic circulation.
different types of CVS1:Bio :8 * *
blood vessels and Practical; 1.5
changes in these Interpretation of Cardiac
vessels like Enzymes
atherosclerosis.
BIOCHEMISTRY
CVS:1 Phy:13 1 * - *
Local control of blood flow
List component of
CVS:1 Phy:18
circulation,
Nervous regulation of
microcirculation, and
functions of arterial circulation and rapid control of
PHYSIOLOGY B.P.
and venous system.
Formation of edema
CVS:1 Phy:19
by applying
Circulatory shock
knowledge of
capillary/lymphatic
exchange CVS:1 Pth :4(a) * *
PATHOLOGY Hypertensive Vascular Disease 1.5
CVS:1 Pth :4(b) * *

Hypertensive Vascular Disease 1.5
231
Lectures
Demo:
Tutorials
Practical
CBL / SBL
Self Study
Library
Digital
ATP
viva
Skills Lab
One Best, MCQS

OBJECTIVES FACULTY
TOPIC / CONTENT
Assessment
CLINICAL CVS:1 Crd:15 * *
FACULTY CBL: Hypertension 1.5
CVS:1 Pha:4a * *
Drugs used in HTN 1 1
PHARMACOLOGY
CVS:1 Pha: 4b Drugs used * *
in HTN 2 1
232
Time Table
First WEEK
Days 8:30 to 9:30 9:30 to 10:30 11:00 to 12:30 1:30 to 3:00

Biochemistry
Overview of Lipid
ANATOMY metabolism including Histology of blood vessels
1 Overview of CVS Cholesterol Name of Faculty SELF STUDY
Name of Faculty Metabolism Venue
Venue
Name of Faculty
Venue
1. A=Histology Practical
blood vessels. Name of
Faculty
Venue
2. B=Bio Pract: =Colrimetry
ANATOMY BIOCHEMISTRY: Name of Faculty
Heart: covering Structure of fatty acids Venue
Biochemistry:
(pericardium)and and compound lipids 3. C= SELF STUDY
2 related to CVS Chemistry synthesis and
external features 4. D= Biochemistry demo lipid functions of Lipoproteins 1
Name of Faculty Name of Faculty profile
Venue Venue
Name of Faculty
Venue
5. E= CBL (LAST OF
RESPIRATORY)
Name of Faculty Venue
1. B
ANATOMY DEMO 2. C
3 Heart: Internal-features 1 3. D
Name of Faculty 4. E
Venue 5. A
1 1. C BIOCHEMISTRY:
0 2. D Chemistry synthesis and functions
ANATOMY
4 Heart: Internal-features 2
: of Lipoproteins 2
3. E
3 Name of Faculty
0 4. A
Venue - 5. B
1
1
:
0
0
S
E
L
F
S
T
U
D
Y
233
SEMESTER II CARDIOVASCULAR MODULE
TIME TABLE WEEK-II
Days 8:30 to 9:30 9:30 to 10:30 11:00 to 12:30 1:30 to 3:00
ANATOMY LAST WEEK PRACTICAL

Biochemistry
Oxidants and Overview of 1. D= Name of Faculty Biochemistry:
antioxidants Coronary Venue Role of Nutrition and antioxidants in
1 Name of blood vessels 2. E CVS Disorders
Faculty Name of 3. A Name of Faculty
Venue Faculty Venue
4. B
Venue 5. C
ANATOMY LAST WEEK PRACTICAL
Histology
Pathology 1. E= Name of Faculty
Of heart PATHOLOGY
Atherosclerosis Venue
including Ischemic Heart Diseases 1
2 Name of 2. A
myocardium Name of Faculty
Faculty 3. B
Name of Venue1
Venue
Faculty 4. C
Venue 5. D
1.A= Physiology Practical:
Measurement of blood pressure by
Pharmacolog auscultation & by cardiac
y microphoneName of Faculty
PATHOLOGY 2.B=Histopathologypractical slides
Lipid
Ischemic Heart ofatherosclerosis
Venue and IHD
3 Diseases 2
lowering SELF STUDY
drugs Name of Faculty Venue
Name of 3.C= Histology practical heart
Name of
Faculty Name of Faculty Venue
Venue Faculty
Venue 4.D= CBL Name of Faculty
Venue
5.E = SELF STUDY
Physiology: 10:00- 1. B ANATOMY DEMO

Properties of Cardiac 10:30 am 2. C Heart, (surface marking of heart and
4
Muscle SELF 3. D= valves, great vessel
Name of Faculty STUDY 4. E
Name of Faculty
Venue 5. A
Physiology: Venue
1. C
Excitatory + conduction 10:00-10:30
system of heart am 2. D
5
Action Potential in SELF 3. E= Name of Faculty
CARDIAC muscle STUDY Venue
Name of Faculty 4. A
Venue
Anatomy: 1. D
5. B
Conducting system, 10:00- 2. E
Blood Supply, Nerve 10:30 3. A= Name of Faculty
6 SELF STUDY
supply SELF Venue
Name of Faculty STUDY
4. B
Venue
5. C
234
TIME TABLE WEEK-III
Days 8:30---9:30 9:30---10:30 10:30---12:00 12:00---1:00
LAST WEEK PRACTICAL

Physiology PHYSIOLOGY 1. E
Mechanism of Cardiac Cycle/ 2. A Physiology:
cardiac muscle Heart Sounds
1 ECG 1: Normal ECG recording and lead system
contraction 3. B= Name of Faculty
Name of Faculty Name of Faculty
Venue Venue
Venue 4. C
5. D
Anatomy PHARMACOLOGY
PATHOLOGY Anatomy :
Early Overview of principle arteries of CVS Anti Anginal Drugs
Development Of Cardiac Failure
2 Name of Faculty
Heart Name of Faculty Name of Faculty
Venue Venue Venue
Name of Faculty
Venue
A1 = SKILL LAB
EXAMINATION OF CVS
A2 = SELF STUDY
B = Physiology Practical: Major Physiology:
Physiology: components of ECG by power Lab,
ECG Abnormalities Hypertrophy and ischemia/
ECG 2: Rate and rhythm + 10:0010:30 Name of Faculty Venue myocardial infarction
3 vectoral analysis SELF
Name of Faculty STUDY C = SELF STUDY
Name of Faculty
Venue
D = Biochemistry Venue
Practical;Interpretation of Cardiac
Enzymes Name of Faculty
Venue
E= CBL
PHARMACOLOG
Physiology: Y: 1. B1
Arrhythmias + Drugs Used In 2. C
4 conduction defects Arrythmias 1 3. D SELF STUDY
Name of Faculty 4. E
Venue
Venue
PHARMACOLOGY: 1. C1
Drugs Used In 10:00 10:30 2. D
5 Arrythmias 2 3. E
SELF
Name of Faculty STUDY 4. A
Venue 5. B
Anatomy
Physiology
Late Development 1. D1
Normal and Clinical Faculty of Radiology
Of Heart And 2. E
abnormal heart X-ray chest in relation to CVS
6 Partitioning Of 3. A
sounds Name of Faculty
Heart 4. B
Name of Faculty 5. C Venue
Name of Faculty
Venue
Venue
235
TIME TABLE WEEK-IV
8:30 to 9:30 9:30 to 10:30
Days 10:30 to 12:00 12:00 to 1:00
Anatomy :
Physiology: LAST WEEK PRACTICAL
Overview Of 1. E
Cardiac Output And
Principle Veins Of 2. D
1 Its Regulation
Cvs. 3. A
Name of Faculty SELF STUDY
Name of Faculty 4. B
Venue 5. C
Venue
1.A2= Skill lab. Examination of cvs
A1= Self study
Physiology:
Anatomy: 2. B=Physiology practical:ECG and
Hemo-Dynamics heart sound
2 Development Of
(Blood Flow, Arterial System Physiology:
Pressure, Resistance,) 3. C= CBL:
Name of Faculty Local Control Of Blood Flow
Name of Faculty Venue 4. D= SELF STUDY Name of Faculty Venue
Venue
5.E= SELF STUDY
Clinical Faculty Cardiology 1. B

10:00- PATHOLOGY
Imaging Techniques ( Echo, 2. C
10:30 Hypertensive Vascular Disease.
3 Angiography, Thalium 3. D
SELF Name of Faculty Venue
Scanning). Name of Faculty 4. E
STUDY
Venue 5. A
Physiology:
Nervous Regulation Of
Circulation And Rapid Control 1. C
10:00- Anatomy: Development Of Venous
Of B.P 2. D
10:30 System. Name of Faculty
4 Long Term Regulation Of 3. E
SELF Venue
Arterial Pressure. 4. A
STUDY
Name of Faculty 5. B
Venue
PATHOLOGY 1. D
PHARMA
Hypertensive Heart Drugs Used In 2. E
5 Disease Hypertension 2 3. A
Name of Faculty Name of Faculty 4. B
Venue 5. C
Venue
Physiology:
PHARMA 1. E
Micro circulation
Drugs Used In 2. A
lymphatic system
6 Hypertension 2 3. B SELF STUDY
and oedema
Name of Faculty 4. C
Name of Faculty
Venue 5. D
Venue
236
LEARNING OBJECTIVES
objectives:
ANATOMY
CVS:1 Ang1OVERVIEW OF CVS
Explain organization of cardio vascular system
Enlist the components of cardio vascular system
Describe about location, external and internal structure of heart
Explain about different chambers and valve of the heart
Discuss the different circulatory circuits and their working .
Describe the structures of different vessels
CVS:1 Ang2ANATOMY OF PERICARDIUM
Definepericardium
Describe different reflectionsof pericardium
Identify entry &exit of vessels of heart via pericardium
Discuss applied anatomyof heart
CVS:1Ang3 (a)CHAMBERS AND INTERNAL FEATURES OF HEART
Discuss the surface marking of the heart

Describe the surface marking of the heart valves
Explain the surface marking of the aorta
Demonstrate the surface marking of the superior vena cava
Demonstrate the surface marking of the inferior vena cava
CVS:1 Ang3 (b)CHAMBERS AND INTERNAL FEATURES OF HEART
Explain the different chambers of the heart

Describe Internal structures of the heart
Describe the different Valves of the heart
CVS:1Ang 4OVERVIEW OF CORONARY ARTERIES

Discuss the main branches of coronary arteries.
Enlist the branches of each main artery.
Describe the anastomosis of coronaries.
237
CVS:1 Ang5CONDUCTINGSYSTEM OF THE HEART, BLOOD SUPPLY
AND NERVE SUPPLY TO HEART
Describe the conduction system of heart

Enlist the different components of conduction system
Describe the blood supply of heart
Describe coronary artery and its branches
Explain theinnervations of heart
CVS:1Ang 6SURFACE
MARKING OF THE HEART,AORTA,SUPERIOR VENA CAVA ,
INFERIOR VENA CAVA
Discuss the surface marking of the heart

Describe the surface marking of the heart valves
Explain the surface marking of the aorta
Demonstrate the surface marking of the superior vena cava
Demonstrate the surface marking of the inferior vena cava
CVS:1 Ang7OVERVIEW OF PRINCIPAL ARTERIES OF THE BODY
Describe the organization of the venous system of the body

Express the great veins opening in to the heart
Discuss the distribution of the veins in the respective region
Evaluate the applied aspect related to the topic
CVS:1Ang8OVERVIEW OF PRINCIPAL VEINS OF THE BODY
Describe the organization of the venous system of the body

Express the great veins opening in to the heart
Discuss the distribution of the veins in the respective region
Evaluate the applied aspect related to the topic.
CVS:1Ang9LYMPHATIC SYSTEM
Define Lymphatic System

Describe the composition of Lymph
Enlist the parts of Lymphatic System
238
HISTOLOGY
CVS: 1 Anh1 (a)HISTOLOGY OF HEART INCLUDING MYOCARDIUM
Discuss the basic structure of blood circulatory system

Enumerate different layers of the walls - of heart
Express the characteristics of cardiac muscle cell
Explain the Structure of Intercalated disc
Define the junctional specializations making up the intercalated disk.
Describe identification of different microscopic views of cardiac muscle and its
ultra structures.
CVS: 1 Anh1 (b)HISTOLOGY OF HEART INCLUDING MYOCARDIUM
Discuss the basic structure of blood circulatory system

Enumerate different layers of the walls - of heart
Express the characteristics of cardiac muscle cell
Explain the Structure of Intercalated disc
Define the junctional specializations making up the intercalated disk.
Describe identification of different microscopic views of cardiac muscle and its
ultra structures.
CVS: 1 Anh2 (a)HISTOLOGY OF BLOOD VESSELS

Discuss the basic structure of blood vessels
Enumerate different layers of the walls - of vessel.
Express the characteristics of blood vessel
Describe identification of different microscopic views of vessel muscle and its
ultra structures.
CVS: 1 Anh2 (b)HISTOLOGY OF BLOOD VESSELS (practical)
Discuss the basic structure of blood vessels
Enumerate different layers of the walls - of vessel.
Express the characteristics of blood vessel.
Describe identification of different microscopic views of vessel muscle and its
ultra structures.
EMBRYOLOGY
CVS: 1 Ane1EARLY DEVELOPMENTOF HEART
Describe Vasculogenesis and Angiogenesis

Illustrate the formation of Endothelial tube
Explain the Carcinogenic Area
Describe the formation of heart tube
239
Evaluate the further development of heart
Discuss the formation of different layers of heart
Explain the division of heart tube
Describe the Rotation of Heart tube
CVS: 1 Ane2 LATE DEVELOPMENT AND PARTITIONING OF THE HEART

Describe the development of heart tube its division and its rotation
Evaluatethe development of Four Chambered Heart
Explain the Interatrial and Interventricular septum formation
Discuss the formation of Heart Valves
Evaluate the formation of Conduction System.
CVS:1 Ane3 DEVELOPMENT OF THE ARTERIAL SYSTEM
Explain the relation of Pharyngeal Arches and Aortic Arches

Evaluate the fate and formation of aortic arches
Describe the formation of Brachiocephalic Trunk, Common Carotid and left
Subclavian arteries
CVS:1 Ane4 DEVELOPMENT OF THE VENOUS SYSTEM

Describe the Veins of Embryo
Describe development and Fate of Umbilical, Vitelline and Cardinal Veins .
PHYSIOLOGY
CVS:1 Phy:1 ARRYTHMIAS AND CONDUCTION DEFECTS IN ECG
Enlist the common cardiac arrhythmias

Describe the electrical events that produce them.
CVS:1 Phy:2 THE CARDIAC CYCLE
Define what is cardiac cycle.

Describe the phases of cardiac cycle.
Describe the relationship of the electrocardiogram to the Cardiac Cycle.
Enumerate the Pressure Changes in the Atria.
Explain the Period of Isovolumic (Isometric) Relaxation.
Interpret the relationship of the Heart sounds with cardiaccycle.
CVS:1 Phy:3 MECHANISMS OF CARDIAC MUSCLE CONTRACTION
Describe the Specialized Excitatory and Conductive System of the Heart.

Define what is primary pace maker.
Discuss the function of internodal pathways.
Explain what are Purkinji Fibers.
240
Define a cardiac myocyte.
Explain the Excitation and Contraction of Cardiac Myocyte.
Enumerate the role of gap Junctions?
CVS:1 Phy:4 BLOOD PRESSURE BY AUSCULTATION AND PALPATION

Define blood pressure
Classify types of blood pressure
Describe the Methods of Blood Pressure (BP) measurement.
Describe the Factors affecting blood pressure
CVS:1 Phy:5 EXCITATION AND CONDUCTING SYSTEM OF HEART
Describe generation of an action potential of heart.

Classify the phases of action potential.
Describe the components of conducting system of heart.
Explain the conducting pathway.
Express the rate of conduction.
CVS:1 Phy:6 ELECTROCARDIOGRAM ECG BASIC PRINCIPLE

Define ECG
Describe the basic principle in generation of ECG waves
Interpret ECG paper and its calibration
Recognize/appreciate/illustrate different leads and their arrangement
Explain the different components of ECG .
CVS:1 Phy:7 RATE AND RHYTHM OF ECG
Enumerate the rate of ECG tracing
Describe how to calculate the rate from ECG tracing
Interpret ruleof 300
Describe sinus rhythm, sinusbradycardia and tachycardia
Explain the overdrive suppression.
CVS:1 Phy:8 VECTORIAL ANALYSISOF ECG
Explain about vector and the principles applied in plotting electrical vector of
heart
Enumerate the relationship between vectors generated in the heart and EKG
waves .Assign appropriate vectors to depolarizing and repolarizing signals at
different angles to the recording electrodes
Describe the concepts of instantaneous vectors and net vectors
Dissect a vector loop into component instantaneous vectors
Reconstruct a vector loop from individual traces
Explain how the hex axial reference system is generated and be able to
identify the individual axes
241
CVS:1 Phy:9 CARDAIC OUTPUT AND ITS REGULATION
Define the terminology of cardiac function: Cardiac output, venous return,

stroke volume and ejection fraction
Identify the factors regulating cardiac output
Explain effect of preload, contractility, and after load on stroke volume and
cardiac output.
Appreciate positive and negative chronotropic and inotropic effects
Discuss the goal of the cardiovascular system is to maintain adequate blood
flow to all body tissues.
CVS:1 Phy:10CVS ADAPTATION DURINGEXERCISE
Outline the circulatory responses to various types of exercise

Identify the factors that regulate local blood flow during exercise
Enlist & discuss those factors responsible for regulation of stroke volume
during exercise
Discuss the regulation of cardiac output during exercise
CVS:1 Phy:11HEMODYNAMICS (BLOOD FLOW, PRESSURE AND RESISTANCE)
Explain the term Hemodynamics

Describe the principles governing the flow of blood in the human body
Explain the factors effecting resistance to flow and how it effects the normal
physiological environment of the body
CVS:1 Phy:12LOCAL CONTROL OF BLOOD FLOW

Describe the intrinsic regulation of blood flow.
Discuss the vasodilator and oxygen lack theories.
Explain the mechanisms of Auto -regulation.
Elaborate the acute metabolic control of local blood flow.
CVS:1 Phy:13NERVOUS REGULATION OF CIRCULATION AND RAPIDCONTROL

OF BLOOD PRESSURE
Define the sympathetic and parasympathetic nervous system and their role in
circulation
Explain vasoconstrictor tone
Describe vasomotor area, its location and function
Differentiate different methods of rapid nervous control of BP
Discuss baroreceptor and other reflexes
Evaluate the role of kidney in blood pressure control.
242
CVS:1 Phy:14NORMAL AND ABNORMAL HEART SOUNDS
Define of heart sounds
Enlist the types of heart sounds
Define Murmurs and types of murmurs
CVS:1 Phy:15ELECTROCARDIOGRAM
Describe where to place electrodes to record the standard limb lead ECG
(leads I, II and III )
Identify the major components of the ECG (P wave, QRS complex, T wave) in
these leads
Relate the electrical activity in the heart to these major components .
CVS:1 Phy:16 ELECTROCARDIOGRAM &HEART SOUNDS
Explain the time relationships between the electrical activity of the heart (as
recorded in the ECG) and the mechanical activity of the heart (as judged from
the heart sounds).
CVS:1 Phy:17CIRCULATORY SHOCK AND BASIC PRINCIPLES OF MANAGEMENT

Define Circulatory Shock.
Explain the physiologic causes of circulatory shock.
Describe the stages of circulatory shock.
Describe Hemorrhagic Shock.
Give details of Neurogenic Shock.
Characterize Anaphylactic Shock.
Give details of Septic Shock.
Explain Physiology of Treatment in Shock
BIOCHEMISTRY
CVS:1 Bio:1Overview of Lipid Metabolism including Cholesterol Metabolism
Classify Lipids
Explain the digestion, absorption and utilization of dietary lipids.
Describe Lipogenesis and Lipolysis.
Identify Lipid malabsorption.
Enumerate the functions of cholesterol
Explain cholesterol synthesis and metabolism
Describe transport of cho
243
CVS:1 Bio:2STRUCTURE OF FATTY ACIDS & COMPOUND LIPIDS RELATED
Define Lipids.
Explain the structure and functions of fatty Acids.
Describeun-saturated&saturatedFatty Acids.
Enumerate non- essential& Essential Fatty Acids.
Explain Simple and Complex Lipids.
CVS:1 Bio:3CALORIMETER (Biochemistry Practical)

Describe the principals of CALORIMETER.
Discuss its mode of mechanism.
CVS:1 Bio:4 Lipid Profile (Biochemistry Demonstration)

Discuss the components of normal lipid profile
Interpret the normal laboratory ranges of lipid profile
Diagnose Hyperlipidemia and its clinical features
Describe the classification of hyperlipidemia
CVS:1 Bio:5(a)CHEMISTRY SYNTHESIS & FUNCTIONS OF LIPOPROTEINS.(HDL)

DefineLipoproteins?
Describe Lipoprotein Particles.
Discuss the composition of Lipoproteins.
List the chemical components of HDL.
Explain the synthesis & role of HDL in Lipid transport.
Enumerate the disorders of plasma Lipoproteins.
CVS:1 Bio:5(b)CHEMISTRY SYNTHESIS & FUNCTIONS OF LIPOPROTEINS.(HDL)
DefineLipoproteins
Describe Lipoprotein Particles.
Discuss the composition of Lipoproteins.
List the chemical components of HDL.
Explain the synthesis & role of HDL in Lipid transport.
Enumerate the disorders of plasma Lipoproteins.
CVS:1 Bio:6OXIDANTS AND ANTI- OXIDANTS
Define Oxidants and Anti-oxidants.

Explain the role of oxidants and anti-oxidants.
Describe oxidants and anti-oxidants.
CVS:1 Bio: 7ROLE OF NUTRITION AND ANTIOXIDANTS IN CARDIOVASCULAR DISEASE
Describe cardiovascular diseases

Describe the common causes of cardiovascular diseases
Explain atheroma formation as the cause of coronary heart diseases
244
Identify the risk factors of coronary heart diseases
Discuss the modifiable risk factors in terms of diet and physical activity
Describe the role of Antioxidants in prevention of cardiovascular diseases
Identify the levels of prevention for cardiovascular disease.
CVS:1 Bio:8Interpretation of Cardiac Enzymes
Interpret certain cardiac enzymes (CPK, LDH, and SGOT) are released from the
heart muscle cells when it is injured ("heart attack").
Evaluate the levels of cardiac enzymes in the blood which is a common test for
the diagnosis of a heart attack and extent of damage done to the heart
PATHOLOGY
CVS:1 Pth:1ATHEROSCLEROSIS
Describe the morphology and distribution of atherosclerotic plaque

Enlist the components of atherosclerotic plaque
Explain the parts of an atheroma
Describe the complications of atherosclerosis.
CVS:1 Pth:2(a)ISCHEMIC HEART DISEASE 1
Describe Ischemic heart diseases.

Classify different Ischemic heart diseases.
Explain the causes and clinical manifestation of Ischemic heart diseases.
CVS:1Pth:2(b)ISCHEMIC HEART DISEASE 2
ANGINA PECTORIS
Define Angina Pectoris

Diagnose the pathogenesis
Explain the causes of Angina Pectoris
Enlist the types of Angina Pectoris
CVS:1 Pth:3CARDIAC FAILURE
Definecardiac failure.
Describe the etiology of cardiac failure,
Discuss the patho-physiology, symptoms and physical signs,
Enlist the types of cardiac failure,
Enumerate the complications of cardiac failure.
Interpret Investigations, management and differential diagnosis of cardiac
failure.
245
CVS:1 Pth:4(a)HYPERTENSIVE VASCULAR DISEASE
Describe the pathogenesis ,symptoms and physical signs of

Hypertensive Vascular Disease.

Enlist the principal manifestations of hypertensive vascular diseases and
explain the early changes in terms of the underlying events that produce
them.
CVS:1 Pth:4(b)HYPERTENSIVE HEART DISEASE
Describe the pathogenesis ,symptoms and physical signs of

hypertensive heart disease.

Enlist the principal manifestations of hypertensive vascular diseases and
explain the early changes in terms of the underlying events that produce
them.
PHARMACOLOGY
CVS:1Pha :1LIPID LOWERING DRUGS
Describe the effect of a representative from each class of lipid-lowering

agent.
Explain the mechanisms and therapeutic advantages and limitations of
different classes of lipid lowering agents.
Discuss the potential impact of agents that modify atherosclerosis and its
sequelae on patient health.
Discuss the magnitude of low-density lipoprotein cholesterol (LDL-C) lowering
and rates of elevated liver enzymes.
CVS:1Pha :2ANTI-ANGINAL DRUGSLECTURE-1
Recognize and categorize different anti- anginal drugs by their mechanism of

action.
Explain how different classes of drugs abolish angina.
List the primary channel or receptor mechanisms ,and how anti- anginal drugs
produce their effects.
Describe the primary drugs used for acute and chronic treatment .
Explain which drugs are useful for reducing ventricular rate..
Cite major side effects of major anti- anginal drugs.
246
CVS:1Pha :3(a)ANTI-ARRHYTHMIC DRUGSLECTURE-1
Describe the drugs used for treatment ofarrhythmias.

Explain which drugs are useful for reducing ventricular rate.
Discuss Enhanced automaticity and Triggered automaticity,
Cite major side effects of major anti-arrhythmic drugs
CVS:1Pha :3(b)ANTI-ARRHYTHMIC DRUGS LECTURE-2
Recognize and categorize different anti-arrhythmic drugs by their mechanism

of action.
Explain how different Classes of drugs abolishes arrhythmias.
List the primary channel or receptor mechanisms by which Class I, II , III and IV
anti-arrhythmic drugs produce their effects.
Describe the primary drugs used for acute and chronic treatment of AV node
reentry.
Explain which drugs are useful for reducing ventricular rate.
major side effects of major anti-arrhythmic drugs.
CVS:1Pha4 (a)DRUGS USED IN HYPERTENSION(LECTURE-1)

Describe the impact and mechanisms involved in essential hypertension.
Explain actions of major classes of antihypertensive drugs.
List the stepwise and monotherapy regiments for treatment of hypertension.
Describe the use of drugs in the treatment of a hypertensive emergency or
crisis.
CVS:1Pha4 (b)DRUGS USED IN HYPERTENSION ( LECTURE-2)
Describe the impact and mechanisms involved in essential hypertension.

Explain actions of major classes of antihypertensive drugs.
List the stepwise and monotherapy regiments for treatment of hypertension.
Describe the use of drugs in the treatment of a hypertensive emergency or
crisis.
247
CVS1 Cardiovascular Module:

I. Introduction To Cardiovascular System Examination:
Introduction/Rationale:
Diseases of cardiovascular system are one of the most common causes of morbidity and
mortality, both in adults and children. Cardio vascular system examination is performed as
an integral part of physical examination, or when a patient presents with cardio vascular
problems (for example: chest pain).
Enumerate the steps of examination of the cardiovascular system (CVS) .
To demonstrate correct technique of auscultation of heart.
CASE BASED LEARNING

CBL 1:
Pain sensitive structures of heart and characteristics of pain originating from

heart
Blood supply of heart and results of its occlusion, pathophysiology of
occlusion
biochemical changes associated with myocardial injury
ECG changes associated with myocardial injury
Risk factors and role of lipids in the pathogenesis of coronary artery disease.
CBL 2:
Recognize different types of congenital heart diseases
Understand the mechanism of cyanosis.
Understand the differences between cyanotic and acyanotic heart diseases
CBL 3:
Define Hypertension, high normal blood pressures and normal blood pressures.
Describe the mechanism of control of blood pressure.
Interpret the role of different organs for the control of blood pressure.
248
WEEK 1st 2nd 3rd 4th TOTAL Round of %

Credit
hours
12.50
GROSS 6.50 1.50 4.50 13.80 0.60
13
ANAT.
EMBR 5.50 5.50 5.75

6 0.34
HISTO 3.00 2.50 1.50 7 7.32

7 0.43
26.00
PHYSIO 10.50 14.00 1.50 27.22 1.34
27
BIOCHEM 10.50 1.50 1.50 13.50 14.13 0.7

14
PHARM 1.50 3.00 3.00 7.50 7.85

8 0.5
12.00
PATHO 3.50 2.50 2.50 3.50 12.56 0.6
13
Clinical
3.00 1.00 4.00 4.18
Faculty 4 0.25
SKILL 1.50 1.57

1.50 2 0.09
LABS
CBL 1.50 1.50 1.50 1.50 6 6.28

6 0.4
TOTAL 26.50 26.00 27.00 16.00 95.50

100 5.37
249
(SEMESTER II)
SUMMATIVE ASSESMENT
THEORY

SEMESTER
ATP 25
EXAM
PAPER-III One best Questions 80%

20
based on CBL
Total 100
MODULE EXAM
EMQs 10
ATP 20 20%
MODULE PAPER
One best Questions
20
based on CBL
Total 100
STRUCTURED VIVA

ASSESMENT
SUMMATIVE
SEMESTER
EXAM
See Semester
PAPER-IV- C Structured viva
Assessment Plan
ASSESMENT TOOLS
Structured Feedback
Facilitator
NOTE:
Paper I& IV-A of Semester 2 Examination are Based on LocomotorModule.
Paper II & IV-B of Semester 2 Examination are Based on Respiration Module.
250
CREDIT HOURS
SEMESTER II
III 3
Cardiovascular
IV-C 1.5
251
CREDIT
HOURS
Locomotor Module
80 Marks
(Semester Theory)
100
I Marks 6
Locomotor Module
20 Marks
(Module Exam)
Respiration Module
40 Marks
(Semester Theory) 50
II Respiration Module Marks 3
10 Marks
(Module Exam)
Cardiovacular Module
40 Marks
III Cardiovacular Module Marks 3
10 Marks
(Module Exam)
Locomotor Module
a
(Viva)
50 Marks 3
Respiration Module 100

IV b
(Viva)
25 Marks
Marks
1.5
Cardiovacular Module
C
(Viva)
25 Marks 1.5
Semester-II Total Credit Hours 18
252
253
SEMESTER -3
Neurosciences-1 Module 8 Weeks 9 Credit Hours
Head & Neck Module 4 Weeks 4.5 Credit Hours
Endocrinology -1 Module 4 Weeks 4.5 Credit Hours
254
NEUROSCIENCES MODULE
CODE: NEU-1
SEMESTER III
SECOND YEAR M.B; B.S
255
Spiral Sem. Modules


Bones, Joints, Nerves & Muscles, 8 Week System 4 wks System 4Week
Spiral
NEU1- Nervous System HNN1- Head & END1- Endocrinology
III 8 weeks Neck & Special 4 weeks
Senses 4 weeks
4 Week
wks
Second th
Spiral th
Trauma, 6 week
3 week 8 Weeks
/ Burns 2 wk
2 Weeks
th
th
PARALLEL THEMES:
256
MODULE COMMITTEE:
Dr. Naheed Khan, Professor of Anatomy, DUHS

Dr. Naila Naeem, Associate Professor of Neurology , DUHS
DR Ruqaiya Shahid, Assistant Professor of Pathology, DUHS
DR Lubna Avesi, Assistant Professor of Pathology , DUHS
Dr. Kelash Nankani, Associate Professor of Physiology, DUHS
Dr. Nadeem Alam, Associate Professor of Biochemistry, DUHS
Dr. Fuad Shaikh, Lecturer of Pharmacology , DUHS
Dr. Saba Sohail, Professor of Radiology , DUHS
DOCUMENT PREPARED BY:

MODULE COORDINATED BY:

DOCUMENT REVIEWED BY:

Module committee
257
RATIONALE
Diseases of the nervous system are common all over the world. Timely diagnosis and
management of acute CNS problems like cerebrovascular accidents and infections
prevents morbidity and mortality. Early diagnosis and prompt treatment of
degenerative and demyelinating diseases like Parkinsons disease and multiple sclerosis
is important to reduce the occurrence of disability burden on community.
Understanding the structure and function of nervous system and its relationship with
pathophysiology of diseases is essential for diagnosis and management The
neurosciences 1 module provides this basic understanding by integrating the teaching of
anatomy, physiology, and function of different structures of the nervous system along
with the biochemistry of neurotransmitters, and the basic pharmacology and pathology
related to the disorders of the central and peripheral nervous system.
TERMINAL OBJECTIVES
AT THE END OF THIS MODULE STUDENT WILL BE ABLE TO:
Describe the anatomy of brain and spinal cord and the general
organization of nervous system.
Analyze the physiology of nervous system and biochemistry of
neurotransmitters
Understand the metabolism the brain of along with the composition of
blood brain barrier
Explain the Mechanism of Ischemia, Hypoxia, infarction and intracranial
hemorrhage
Summarize all the cranial nerves with their associated clinical correlates
Elaborate the approach to a neurologic patient with its screening
258
methodology
BCQS, SEQS EMQS

DIGITAL LIBRARY
SELF STUDY
TUTORIALS
PRACTICAL
PRACTICAL
LECTURES
SKILL LAB
LIBRARY
VIVA
CBL
LEARNING OBJECTIVES FACULTY TOPIC/CONTENT
Modes of information Transfer Assessmen

t
Recognize the structure ANATOMY NEU1 Ang1:Skull as a 1 * * *

and function of major whole and vault of Skull
division and + Anterior Cranial fossae
components of central, HISTOLOGY NEU1 Anh1: General 1 * * *
peripheral and organization of Nervous
autonomic nervous system
system Different types of nerve
tissue-
(Neurons and Neuroglia)
NEU1 Phy1 : Neuron 1 * *
membrane potential:
Generation and
propagation of Nerve
PHYSIOLOGY impulse
NEU1 Phy2 : Sensory 1 * *
Receptors (including
Muscle spindle) and
Neuronal circuits
ANATOMY NEU1 Ang2 : Skull 1 * *
:Middle and posterior
Cranial fossae 2
HISTOLOGY NEU1 Anh2 : Structure of 1 * *

Neuron and neuroglia
NEU1 Phy3 : Overview of 1 * *

Peripheral Nervous
system
PHYSIOLOGY
NEU1 Phy4 : Types of 1 * **
nerve fibers, its
regeneration and
degeneration, Synapses
including Properties
PATHOLOGY NEU1 Pth1 : Patterns of 1 * *
nerve injury and
Regeneration of Neurons
259
ANATOMY NEU1 Ang3 : Organization 1 * *
of Autonomic Nervous
system
PHYSIOLOGY NEU1 Phy5 : Functions 1 * *

and integration of
Autonomic Nervous
system
NEUROLOGY NEU1 Neu1 : Approach to 1 *
Neurologic patient
ANATOMY NEU1 Ang4 : Models Of 1.5 *

Brain & Spinal Cord
NEU1 Neu2 : Screening 1 * * *

Neurological Examination
NEUROLOGY NEU1 Neu3 : 1 * *

Electrophysiological
investigation of
neurological disorders
(EEG & EMG/NCV)
PHYSIOLOGY NEU1 Phy6 : EEG 1.5 *
Recognize the structure NEU1 Ang5 : Structure of 1.5 *

and function of major Diencephalon I
division and (Thalamus)
components of central, Structure of
peripheral and Diencephalon II
autonomic nervous ANATOMY (Epithalamus,
system, with the role of subthalamus and third
hypothalamus ventricle)
NEU1 Ang6 : Structure of 1 *
Diencephalon III
(Hypothalamus)
NEU1 Phy7 : Functions of 1 * *

Hypothalamus
PHYSIOLOGY NEU1 Phy8 : Functions of 1 * *

Diencephalon
(Thalamus, Epithalamus,
subthalamus)
ANATOMY NEU1 Ang7 1.5 *
:Diencephalon
Identify various NEU1 Ane1:Development 1 * *

congenital of Nervous system and
malformations of brain Neurulation
and spinal cord by EMBRYOLOGY NEU1 Ane2 1 * *
knowing the :Development of
embryological basis of Forebrain +
260
neurulation and Developmental
transformation of Anomalies of CNS
neural tube into CNS
and the anomalies in
the process PATHOLOGY NEU1 Pth2 1 * *
:Developmental
anomalies of CNS
Interpret the various NEU1 Ang8 :Spinal Cord 1.5 * * *
clinical presentations of I+
spinal cord disorders Arterial Supply and
correlating with its Venous Drainage
organization, structure NEU1 Ang9 :Meninges of 1 *
and function. brain and spinal cord
ANATOMY
NEU1 Ang10 : Spinal Cord 1 *
II
NEU1 Ang11 : Spinal cord 1 * *

(Structure + Tracts)
HISTOLOGY NEU1 Anh3 :Spinal Cord 1 *
ANATOMY NEU1 Ang12 :Lesions of 1 * * *

spinal cord
RADIOLOGY NEU1 Rad1 :Radiology. CT 1 * * *

scan and MRI of Spinal
Cord
PHYSIOLOGY NEU1 Phy9 :Organization, 1 *

location and function of
different descending
pathways
Localize the common ANATOMY NEU1 Ang13 : Anatomy of 1 * *

brain stem and cranial brain stem and
nerves lesions by associated lesions:
recognizing the Medulla Oblongata
structure of brainstem PHYSIOLOGY NEU1 Phy10 :Motor, Vital 1 * *
and the associated and non-vital functions of
cranial nerves. Brain Stem (respiratory,
cardiac, vasomotor
centers and coughing,
sneezing and vomiting
reflexes)
NEU1 Ang14 :Anatomy of 1 * *
brain stem and
associated lesions: Pons
261
NEU1 Ang15 :Anatomy of 1 * *
brain stem and
associated lesions:
midbrain
NEU1 Ang16 :Summary of 1.5 * *
ANATOMY cranial nerve(1-6) nuclei
+associated clinical
correlates
NEU1 Ang17 : Summary 1.5 * *
of cranial nerve (7-12)
nuclei
correlates
Deduce the neuro- HISTOLOGY NEU1 Ane4 :Histology of 1 * * *
anatomic basis of Cerebellar Cortex
ataxia and
incoordination by NEU1 Phy11 :Physiologic 1 * *
applying the knowledge correlates of various
of cerebellar cortex, parts of cerebellum and
nuclei and peduncles. its function; Effects of
Cerebellar dysfunction
Identify different PHYSIOLOGY NEU1 Phy12 1 * *
modalities of sensation :Organization, location
and correlate the lesion and function of different
in sensory system with ascending pathways
the organization of NEU1 Phy13 :Physiology 1 * *
ascending pathways, of pain
receptors and thalamus
along with the role of BIOCHEMISTRY NEU1 Bio1 :Serotonin and 1 * *
serotonin and other pain
pain modulators.
Predict the clinical NEU1 Phy14 : Motor 1 * *
significance of the functions of Spinal cord
various superficial and + Reflex arc
deep reflexes by PHYSIOLOGY NEU1 Phy15 : 1 * *
applying the knowledge Examination of
of their path ways and Superficial and deep
functions. reflexes
Differentiate between ANATOMY NEU1 Ang18 : Gray 1 * *
the functions of matter of cerebral
dominant and non- hemisphere:
dominant cerebral CEREBRAL CORTEX
hemispheres and Surfaces, lobes, sulci and
between various parts gyri of cerebral
of each hemisphere by hemisphere.
identifying the surfaces, HISTOLOGY NEU1 Anh5 :Microscopic 1 * *
lobes, sulci &gyri of anatomy of cerebral
cerebral hemisphere. cortex
NEU1 Ang19 :Functional 1 * *
areas of cerebral cortex
and their associated
lesion
NEU1 Ang20 : White 1.5 * *
matter of cerebral
hemisphere Projection
262
fibers:
Internal capsule and
ANATOMY related anomalies
NEU1 Ang21 :White 1.5 * *
matter of cerebral
hemisphere Commissural
fibers and association
fibers
NEU1 Ang22 :White 1 * *
matter of Brain
Differentiate between
pyramidal and
extrapyramidal
syndromes and upper
and lower motor
neuron lesions with the
knowledge of structure
and types of fiber
bundles traversing the
brain and their
functions
Correlate the BIOCHEMISTRY NEU1 Bio2 :Metabolism 1 * *
presentation of ofAcetylcholine
Parkinsons disease with
the topographic
anatomy and function
of basal nuclei
ANATOMY NEU1 Ang23 :Gray matter 1 * *

of cerebral hemisphere:
Basal nuclei
PHYSIOLOGY NEU1 Phy16 :Basal 1 * *
ganglia and Disorders
BIOCHEMISTRY NEU1 Bio3 : Dopamine 1 * *

and parkinsonism
PHYSIOLOGY NEU1 Phy17 :Disorders Of 1.5 * *

Basal Ganglia
Appreciate the changes ANATOMY NEU1 Ang24 :Limbic 1 * *

in emotions, behavior system
and personality by
recalling the structure
PHYSIOLOGY NEU1 Phy18 :Limbic 1 * *
and functions of limbic
system
system.
Interpret the effects of ANATOMY NEU1 Ang25 :Fourth 1.5 * *

increased intracranial ventricle & cerebral
pressure with the aqueduct
structure of
NEU1 Ang26 : Lateral 1 * *
craniospinal meninges,
Ventricles of Brain +
ventricular system, and
Choroid Plexus
263
mechanism of PHYSIOLOGY NEU1 Phy19 : CSF 1 * *
formation, flow, formation, circulation
drainage and chemistry and functions
of C.S.F in normal and BIOCHEMISTRY NEU1 Bio 4:Chemical 1 * *
in disease. Composition of CSF and
changes in diseased State
PATHOLOGY NEU1 Pth3 :Cerebral 1 * *
edema, Hydrocephalus,
Raised intracranial
pressure and herniation
BIOCHEMISTRY NEU1 Bio5 :Chemical 1.5 * * *
Analysis of CSF
Correlate between COMMUNITY NEU1 Com1 :Endemic 1 * *
clinical presentations MEDICINE diseases involving
and pathogenic Nervous System:
mechanisms involved in Poliomyelitis, rabies,
CNS infections and Diphtheria, Tetanus
infestations PATHOLOGY NEU1 Pth4 :Inflammation 1 * *
of brain and meninges
Relate the different ANATOMY NEU1 Ang27 :Arterial 1.5 * *

syndromes of ischemia Supply of Brain and
in anterior and Spinal Cord
posterior circulation of
brain and ischemic
myelopathy with the
pattern of arterial NEUROLOGY NEU1 Neu4 :Gross clinical 1 * *
supply of brain and effects of territorial
spinal cord, together blockage of arteries
with knowledge of
blood brain barrier.
COMMUNITY NEU1 Com2 :Risk Factors 1 * *

MEDICINE Causing Stroke And Their
Prevalence In Community
BIOCHEMISTRY NEU1 Bio6 : Chemical 1 * *

composition of BBB +
Breach of BBB
NEU1 Pth5 :Mechanism 1 * *

of Ischemia Hypoxia,
infarction and
intracranial hemorrhage
PATHOLOGY
NEU1 Pth6 : Hypertensive 1 * *
cerebrovascular disease
and
intracranial hemorrhage
264
Recognize the effects of NEU1 Ang28 :Venous 1.5 * *
venous stasis and drainage of brain and
obstruction by applying spinal cord +
the knowledge of Dural venous sinuses
venous drainage and ANATOMY
dural venous sinuses
NEU1 Ang29 :Meninges 1.5 * *

And Dural Venous
Sinuses
Assess the higher BIOCHEMISTRY NEU1 Bio7 : Introduction 1 * *
mental functions and and classification of
appreciate their loss in Neurotransmitters
dementia by recalling NEU1 Phy20 :Functions of 1.5 * *
the mechanisms of neurotransmitters
cognition, memory, and
retrieval, with special PHYSIOLOGY
knowledge of NEU1 Phy21 : Learning 1 * *
neurotransmitters and and Memory
papez circuit.
Identify electrical PHYSIOLOGY NEU1 Phy22 :Reticular 1 * *

activity of brain and its Activating System
different wave forms Sleep and its disorders
with the knowledge of
sleep and awake states
Identify the energy NEU1 Bio8 :Brain needs in 1 * *
needs and metabolism different metabolic states
of Brain in well-fed, BIOCHEMISTRY
fasting, starvation and
disease states
NEU1 Bio9 :Role of free 1 *
radical injury in
neurodegenerative
process
BEHAVIORAL SCIENCES NEU1 Beh1 :Perception 1 * *
NEU1 Beh2 :Thinking 1 * *

BEHAVIORAL
SCIENCES
NEU1 Beh3 : Emotion 1 * *
265
TIME TABLE
FIRST WEEK
08:30 to 09:30 to 10:30 to 12:30 1:30 to 3:00

Days 09:30 10:00
1-Physiology Tutorial: Gp A
Overview of Peripheral Nervous
Physiology system Name of facultyVenue
Anatomy
General Revisit: 2-Anatomy Histology
Neuron Practical: Gp B Structure of
Anatomy organization of
membrane Neuron and neuroglia Name of
Nervous system
Skull as a whole and vault of potential: facultyVenue
Different types of
1 Skull Generation and
+ nerve tissue- 3-: GP: C1 skill lab first aid
propagation of
Anterior Cranial fossae 1 (Neurons and part 2
Nerve impulse
Name of faculty Venue Neuroglia) C2= self study
Name of
Name of faculty 4- Gp D Anatomy Museum
faculty
Venue (Bones Of Skull) Name of
Venue
facultyVenue
5-Gp E self study
2 PhysiologyREVISIT Anatomy 1. B
Types of nerve fibers, its Skull :Middle and posterior 2. C
Biochemistry
regeneration and degeneration, Cranial fossae
Physiology 2
Physiology 1.
3. C
D
3
Introduction and classification
Synapses including Properties FunctionsName
of of faculty Sensory 2.
4. D
E
ofName
Neurotransmitters
Anatomy Venue Receptors
neurotransmitters
Anatomy 3.
1. E
D
of faculty 5. A
4. A
4 Spinal Name of facultySupply
CordVenue
I+Arterial Name
Meninges of brain (including
of faculty and spinal Muscle
cord 2. E
5. B
Venue
Anatomy
and Venous Drainage VenueName of facultyspindle) and 3. A
PHYSIOLOGY
Spinal
A+BCord
- II Venue Neuronal circuits 4. B
Motor functions of Spinal cord+Reflex
A+B Name
C+D Name ofof facultyVenue
facultyVenue Name of faculty 5. C
5 arc
C+D DR. Name of
EName of facultyVenue Venue
Name of faculty
facultyVenue
Venue
EName of facultyVenue
Physiology:
Pathology 1. E
Organization, location and
Patterns of nerve injury and 2. A
function of different ascending
6 Regeneration of Neurons 3. B
pathways
Name of faculty 4. C
Name of faculty 5. D
Venue
Venue
266
NEUROSCIENCES MODULE SEMESTER III
WEEK-2 TIME TABLE
Day
8:30-10:00 10:30-11:30 11:30 -12:30 1:30 to 03:00
s
1-Anatomy Histology
Practical: Gp A Spinal Cord
2- Gp B= CBL
PHYSIOLOGY: PATHOLOGY 3- Gp C1=skill lab first aid
Organization, location and Patterns of nerve injury and Regeneration of part 2
1 function of different C2= self study
Neurons
ascending pathways 4- D Self study
Name of facultyVenue Name of facultyVenue
5- Physiology Practical
Examination of Superficial
and deep reflexes: Gp E
Name of facultyVenue
PHYSIOLOGY: PHYSIOLOGY: BIOCHEMISTR 1. B
Organization, location and REVISIT Y REVISIT 2. C
2 function of different Physiology of pain Serotonin and pain 3. D
descending pathways Name of Name of 4. E
Name of facultyVenue facultyVenue facultyVenue 5. A
PHYSIOLOGY
ANATOMY Motor, Vital and non- PHARMACOLOG 1. C
Anatomy of brain stem and vital functions of Brain Y:REVISIT 2. D
associated lesions: Medulla Stem (respiratory,
3 Opioids analgesics 3. E
Oblongata cardiac, vasomotor Name of 4. A
centers and coughing, facultyVenue 5. B
Name of facultyVenue sneezing and vomiting
reflexes) Name of
ANATOMY Anatomy of facultyVenue 1. D
brain stem and associated ANATOMY (Revisit) 2. E
4 lesions: Pons Spinal cord (Structure + Tracts) 3. A
Name of facultyVenue Name of facultyVenue 4. B
5. C
10:00- 12:00
ANATOMY
PHYSIOLOGY:
Anatomy of brain stem and
5 Physiologic correlates of various parts of
associated lesions: midbrain
cerebellum and its function; Effects of
Cerebellar dysfunction
CM
Endemic diseases ANATOMY 1. E
ANATOMY:
involving Nervous Fourth ventricle & 2. A
Histology of Cerebellar
6 System: Poliomyelitis, cerebral aqueduct 3. B
Cortex
rabies, Diphtheria, Name of 4. C
Tetanus facultyVenue 5. D
267
SEMESTER III
WEEK 3 TIME TABLE (UPDATED)
DAY 8.30-10:00 10.30-12.30 1:30 to 03:00
ANATOMY
PHYSIOLOGY:
ANATOMY Structure of Diencephalon I (Thalamus)
Functions of Diencephalon
Lesions of spinal cord Structure of Diencephalon II
1 (Thalamus, Epithalamus,
Name of facultyVenue. (Epithalamus, subthalamus and third
subthalamus)
ventricle)
CLINICAL
PHYSIOLOGY: FACULTY:
ANATOMY ANATOMY REVISIT
Functions of Radiology. CT scan
Structure of Diencephalon III Organization of Autonomic
2 Hypothalamus and MRI of Spinal
(Hypothalamus) Nervous system
Name of Cord
facultyVenue Name of
facultyVenue
PHYSIOLOGY:
ANATOMY
REVISIT ANATOMY REVISIT
REVISIT Organization of Autonomic
Functions of
3 Structure of Diencephalon III SELF STUDY
Nervous system
Hypothalamus
(Hypothalamus)
Name of Name of facultyVenue
facultyVenue
268
NEUROSCIENCES MODULE SEMESTER III
WEEK-4 TIME TABLE
Days 8:30-10:00 10.30-12.30 1:30 to 03:00
Anatomy: Histology:
Gray matter of cerebral Biochemistry: PHYSIOLOGY
Microscopic Metabolism
hemisphere: REVISIT
anatomy of
1 CEREBRAL CORTEX ofAcetylcholine Functions and integration of Autonomic
cerebral cortex
Surfaces, lobes, sulci and gyri of Name of Nervous system
Name of
cerebral hemisphere. facultyVenue Name of facultyVenue
Name of facultyVenue facultyVenue
HistologyPractical:GP:A
Microscopic anatomy of cerebellar
Anatomy:
Gray matter of cortex R. RIAZ UNAR
. Physiology:
Anatomy: cerebral Gp: B CBL:
Basal ganglia and
Functional areas of cerebral hemisphere:
2 Basal nuclei Disorders GP: CBio tuto: Types of
cortex and their associated lesion
Name of Name of Neurotransmitter
facultyVenue facultyVenue
GP: DPHYSIO TUTO
GP: E= SELF STUDY
Anatomy: Embryology
Biochemistry: 1. B
White matter of cerebral Development of
Dopamine and 2. C
hemisphereProjectionfibres: Nervous system and
3 parkinsonism 3. D
Internal capsule and related Neurulation
Name of 4. E
anomalies Name of
facultyVenue 5. A
08:30 10:00 10:00 to 11:00
Anatomy:
Anatomy:
Lateral Ventricles
White matter of cerebral
4 of Brain +
hemisphereCommissural fibres
Choroid Plexus
and association fibres
Name of
A+B= Name of facultyVenue facultyVenue
REVISIT
Anatomy: 1. D
White matter of cerebral 2. E
5 hemisphereCommissuralfibres 3. A
4. B
and association fibres
5. C
REVISIT Anatomy Lecture

Anatomy: Development of 1. E
Anatomy: Lateral Ventricles 2. A
Forebrain +
Arterial Supply of Brain and of Brain + 3. B
6 Developmental
Spinal Cord Choroid Plexus Anomalies of CNS 4. C
Name of facultyVenue Name of 5. D
Name of
facultyVenue
facultyVenue
269
SEMESTER III, NEUROSCIENCES
WEEK 05 TIMETABLE
DAYS 8:30 10:00 10:30 11:30 11:30 12:30 1:30 3:00

Clinical Faculty of Pathology LAST WEEK PRACTICAL
Neurology Developmental E
SELF
Gross clinical effects of anomalies of CNS A
1 ASSESMENT
territorial blockage of B
TEST DR Name of
arteries C
Name of facultyVenue facultyVenue D
Gp: A= HistologyPractical:
Microscopic anatomy of
Physiology: Biochemistry: cerebral cortex
Chemical
Anatomy: CSF formation, Composition of CSF Case Based LearningGp: B
Venous drainage of brain circulation and and changes in
2
and spinal cord + functions diseased State Gp: C Models Of Brain &
Dural venous sinuses Name of Name of Spinal Cord
Name of facultyVenue facultyVenue facultyVenue Gp: DPhysioTuto Disorders
Of Basal Ganglia
5-:GpE SELF STUDY
CM
Biochemistry
REVISIT Risk Factors Chemical B
ANATOMY Causing Stroke composition of C
3 Meninges And Dural And Their BBB + D
Venous Sinuses Prevalence In Breach of BBB
Community E
Name of facultyVenue Name of
Name of facultyVenue A
facultyVenue
Pathology Cerebral
Pharmacology edema,
Classify antithrombotics, REVISIT Hydrocephalus, C
anti platelets and ANATOMY Raised intracranial D
4 fibrinolytics their Diencephalon pressure and E
indications / contra Name of herniation A
indication facultyVenue Name of B
Pathology D
Mechanism of Ischemia E
5 Hypoxia, infarction and A
intracranial hemorrhage B
Name of facultyVenue C
PATHOLOGY: Clinical Faculty: E
Biochemistry
Inflammation of Radiology. CT scan A
Brain needs in different
6 brain and meninges and MRI of Brain B
metabolic states
Name of Name of C
facultyVenue facultyVenue D
270
SEMESTER III NEUROSCIENCES MODULE
WEEK 6 TIME TABLE
Days 8.30-10 10.30-11.30 11.30-12.30 1:30 to 03:00
1-A= CBL
PATHOLOGY 2-PHYSIOLOGY PRACTICAL:
Hypertensive PHYSIOLOGY
ANATOMY: Gp: B= EEG
cerebrovascular disease Reticular Activating Limbic system
1 3-BIOCHEMISTRY
and System Name of PRACTICAL: Gp: C=
intracranial hemorrhage Sleep and its disorders facultyVenue Chemical Analysis of CSF
4-D=SELF STUDY
5- E= SELF STUDY
BIOCHEMISTRY
Role of free radical
1. B
REVISIT ANATOMY PHYSIOLOGY: injury in 2. C
2 White matter of Brain Limbic system neurodegenerative 3. D
Name of facultyVenue Name of facultyVenue process 4. E
Name of 5. A
facultyVenue2
FACULTY OF PHYSIOLOGY:
1. C
NEUROLOGY REVISIT ANATOMY Learning and 2. D
3 Approach to Neurologic Anatomy of Cerebellum Memory 3. E
patient Name of facultyVenue Name of 4. A
Name of facultyVenue facultyVenue 5. B
ANATOMY
FACULTY OF NEUROLOGY ANATOMY Summary of cranial
Summary of cranial 1. D
Screening Neurological nerve (7-12) nuclei 2. E
nerve(1-6) nuclei
4 Examination +associated clinical 3. A
Name of facultyVenue correlates 4. B
correlates
Name of 5. C
facultyVenue
FACULTY OF NEUROLOGY 1. E
Elector physiologic 2. A
5 investigations of 3. B
neurological disorders 4. C
(EEG & EMG/NCV) 5. D
6 SELF STUDY
271
At the end of lecture student should be able to:
ANATOMY
NEU1 Ang1 : Skull as a whole and vault of Skull + Anterior Cranial fossae
Identify parts of skeleton (axial and appendicular)

Identify parts of skull&Sutures of skull
Describe different bones of skull& different views (Norma) of skull
Describe Interior of the skull& divisions of the cranial fossa
Describe Anterior cranial fossa, Foramens and structures passing through them
NEU1 Ang2 : Skull :Middle and posterior, Cranial fossae 2
Describe Interior of the skull& divisions of the cranial fossa

Describe middle cranial fossa, Foramens and structures passing through them
Describe posterior cranial fossa, Foramens and structures passing through them
NEU1 Ang3 : Organization of Autonomic Nervous system
Define Autonomic Nervous System.

Enumeratedivisions of the ANS into Sympathetic & Parasympathetic Systems.
Identify levels of autonomic control.
Compare somatic and autonomic systems.
Compare Sympathetic & Parasympathetic Systems.
NEU1 Ang5 : Structure of Diencephalon I (Thalamus), Structure of Diencephalon II, (Epithalamus,

subthalamus and third ventricle)
Describe the structure and divisions of Diencephalon
Explain the boundaries of diencephalon
Narrate the functions, nuclei and connections of Thalamus, Epithalamus, subthalamus and
third ventricle
NEU1 Ang6 : Structure of Diencephalon III(Hypothalamus)

Explain the boundaries of diencephalon
Narrate the functions, nuclei and connections of hypothalamus
272
NEU1 Ang7 : Diencephalon (revisit)

Identify the boundaries of diencephalon
NEU1 Ang8 : Spinal Cord I+ Arterial Supply and Venous Drainage
Describe parts of spinal cord and arterial supply & venous drainage of the spinal cord
Describe division of the arterial system into Carotid & Vertebral Systems
Different areas of spinal cord supplied by different branches of these arterial systems &
drainage by venous system
NEU1 Ang10 : Spinal Cord II
Describe Ascending and descending tracts.

Identify Nuclei of spinal cord.
Lesions of these tracts.
Common lesions related to spinal cord.
NEU1 Ang11 : Revisit- Spinal cord (Structure + Tracts)
Describe parts of spinal cord and arterial supply & venous drainage of the spinal cord
Describe Ascending and descending tracts.
Identify Nuclei of spinal cord.
Lesions of these tracts.
Common lesions related to spinal cord.
NEU1 Ang12 :Lesions of spinal cord
Describe Lesions of Ascending and descending tracts.

Describe Common lesions related to spinal cord.
NEU1 Ang13 : Anatomy of brain stem and associated lesions: Medulla Oblongata
Describe the detailed Anatomy of medulla oblongata

Define its location
Describe the External features
Describe the Internal structure at four different levels (sections)
Explain the Applied anatomy of medulla oblongata
NEU1 Ang14 : Anatomy of brain stem and associated lesions: Pons
273
Explain external features of pons
Describe internal structure of pons
Explain Lesions of pons
NEU1 Ang15 : Anatomy of brain stem and associated lesions: midbrain
Explain external features of midbrain

Enumerate Cranial Nerves of the Midbrain
Describe internal structure of midbrain
Explain Lesions of midbrain
NEU1 Ang16 : Summary of cranial nerve(1-6) nuclei +associated clinical correlates
Enumerate Cranial Nerves I VI

Explain Lesions of each cranial nerves with its clinical presentation & diagnostic tests
NEU1 Ang17 : Summary of cranial nerve (7-12) nuclei +associated clinical correlates
Enumerate Cranial Nerves VII XII

Explain Lesions of each cranial nerves with its clinical presentation & diagnostic tests
NEU1 Ang18 :Gray matter of cerebral hemisphere: CEREBRAL CORTEX Surfaces, lobes, sulci and
gyri of cerebral hemisphere
Describe anatomicalstructures of cerebral cortex as surface, lobes, sulci &gyri
Explain the dominance & non-dominance correlation with structure & functions of cerebral
cortex
NEU1 Ang19 : Functional areas of cerebral cortex and their associated lesion
Describe different functional areas of cerebral cortex including Motor areas, Sensory
areas&Association areas
Describe lesions associated with functional areas
NEU1 Ang20 :White matter of cerebral hemisphere Projection fibers: Internal capsule and
related anomalies
Give definition, location & relation of internal capsule.
Explain connections of internal capsule.
Describe Parts of internal capsule &Fiber tracts of the internal capsule.
Explain Blood supply of internal capsule.
Give Clinical correlation of related sturctures.
NEU1 Ang23 : Gray matter of cerebral hemisphere: Basal nuclei
identify the location and components of basal nuclei.
274
explain the connections of basal nuclei.
describe clinical aspects related to basal nuclei.
NEU1 Ang25 : Fourth ventricle & cerebral aqueduct
Identify the ventricles of brain along with their location.

Explain the structure and location of fourth ventricle
Explain the structure and location of cerebral aqueduct
Explainthe normal CSF secretion and circulation.
Define the Blood brain barrier
Describe the Applied anatomy of ventricles and CSF flow
NEU1 Ang26 :Lateral Ventricles of Brain + Choroid Plexus
Identify the lateral ventricle and its boundaries

Describe the applied aspects of lateral ventricle.
NEU1 Ang27 : Arterial Supply of Brain and Spinal Cord
Describe Arterial supply of the brain

Describe division of the arterial system into Carotid & Vertebral Systems
Identify Branches of Internal carotid &Vertebral arteries.
Different areas of brain supplied by different branches of these arterial systems & blood
supply of areas other than cerebral cortex
explain applied aspects related to the blockage & Hemorrhage of blood vessels
supplying brain
NEU1 Ang28 : Venous drainage of brain and spinal cord + Dural venous sinuses
Explain venous drainage of brain and spinal cord

Identify the dural venous sinuses
NEU1 Ang29 : Meninges And Dural Venous Sinuses
Define Meninges.
DescribeFunctions of Meninges.
Explain Composition of Meninges.
Describe Dura Mater &duralinfoldings.
Explain the Dural Venous Sinuses.
Describe the Arachnoid and the Pia Mater.
Describe the Meningeal Spaces.
275
EMBRYOLOGY
NEU1 Ane 1: Development of Nervous system and Neurulation
explain brief organization and function of nervous system

explain in depth the development of neural tube, and neural crest cells and their
derivatives.
describe the details of development of various parts of brain and spinal cord.
explain the steps of myelination.
NEU1 Ane2 : Development of Forebrain + Developmental Anomalies of CNS
explain brief organization and function of nervous system

explain in depth the development of neural tube, and neural crest cells and their
derivatives.
HISTOLOGY
NEU1 Anh1 : General organization of Nervous system : Different types of nerve tissue- (Neurons
and Neuroglia)
Describe the nervous tissue
Define neuron, its structure and function
Enlist types of neurons according to structure
Enlist types of neurons according to functions
Define neuroglia, their types and functions
NEU1 Anh2 : Structure of Neuron and neuroglia
Describe the histological structure of neuron & identify its division

Describe the histological structure of neurolgia
NEU1 Anh3 : Spinal Cord
Describe white matter.

Describe Gray Matter.
Identify structures in the gray and white matter.
NEU1 Anh4 : Histology of Cerebellar Cortex
Describe in short review about gross anatomy of cerebellum

Describe the layers of cerebellar cortex
Describe the cells of cerebral cortex
276
Describe Deep Nuclei of Cerebellum
NEU1 Anh5 : Microscopic anatomy of cerebral cortex
Describe in short review of gross anatomy of cerebral hemisphere.

Identify the types of cerebral cortices.
Explain different types of cells of cerebral cortex.
Describe the layers of different cerebral cortices
BIOCHEMISTRY
NEU1 Bio1 : Serotonin and pain
explain Chemistry of serotonin.

Describe the role of serotonin in CNS.
Describethe relationship of serotonin and pain.
give serum Levels of serotonin.
Define Serotonin toxicity& describe its clinical presentation .
NEU1 Bio2 : Metabolism of Acetylcholine
illustrate Structure of acetylcholine

describe Synthesis, transport and degradation of acetylcholine
describe Acetylcholine Receptors& its functions
explain functions of Acetylcholine
Describe disorders underlying acetylcholine receptor dysfunction
NEU1 Bio3 : Dopamine and parkinsonism
Describe metabolism of Dopamine

Explain the distribution of Dopamine in CNS
Explain the role of Dopamine in central CNS pathways
Describe dopamine relation with Parkinsons disease
Describe clinical features of Parkinsonism
Give treatment of Parkinsons disease
NEU1 Bio 4: Chemical Composition of CSF and changes in diseased State
define cerebrospinal fluid.

Explain Mechanism of formation &Absorption of CSF.
Give Composition, characteristics of CSF.
277
Describe Circulation.
Give indication of CSF examination.
Enumerate Changes in CSF in diseases states.
NEU1 Bio5 :Chemical Analysis of CSF

NEU1 Bio6 : Chemical composition of BBB + Breach of BBB
Explain composition of BBB(Blood Brain Barrier).

Define BBB break.
Identify Diseases effecting BBB.
Enlist Drugs targeting brain.
Describe drug delivery across BBB
NEU1 Bio7 : Introduction and classification of Neurotransmitters
Explain the different types of Neurotransmitters in CNS.

Give classification of Neurotransmitters
Explain mechanism of action of various types of Neurotransmitters
Describe the neurotransmitter receptors types & functions.
NEU1 Bio8 : Brain needs in different metabolic states
Explain the mechanism and mode of metabolism in a post absorptive state.

Describe the brain in well fed, postabsorptive and fasting states.
Explain the removal of ammonia and glutamate from the brain.
NEU1 Bio9 :Role of free radical injury in neurodegenerative process
Enumerate thedifferent free radicals, formation and role of Free radicals

Describe the useful and harmful effects of free radicals
Lists the neurodegenerative diseases
Describe the cellular and non-enzymatic antioxidants
EnumerateAntioxidants taken in the diet
278
PHYSIOLOGY
NEU1 Phy1 : Neuron membrane potential: Generation and propagation of Nerve impulse
Explain Principles of neuronal resting membrane potential, action potential, gating of the
action potential, threshold potential and significance of Nernst equation.
Define the absolute and relative refractory period.
Describe Propagation of action potential
Give Significance of saltatory conduction
Describe difference between the myelinated and non-myelinated nerve conduction
NEU1 Phy2 : Sensory Receptors (including Muscle spindle) and Neuronal circuits
Define receptor
Describe Types of receptor
Explain adaptations in receptors
Explain Properties of receptors
Describe Receptor potential
Types of nerve fibers, its regeneration and degeneration, Synapses including

NEU1 Phy4 :
Properties
Define a nerve fibre, its structure and function
Define and describe a motor fibre and a sensory fibre
Define and describe the nerve, its coverings and types
NEU1 Phy5 :Functions and integration of Autonomic Nervous system
Describe divisions of ANS.

Explain Pre-ganglionic and Post ganglionic fibers.
Identify Receptors types in the ANS.
Explain Functions of sympathetic and parasympathetic system.
Explain Role of adrenal glands in ANS.
NEU1 Phy7 : Functions of Hypothalamus
Describe functions of hypothalamus

Explain the neurotransmitters functioning in hypothalamus
Explain the neuronal control of hypothalamic functions
279
NEU1 Phy8 : Functions of Diencephalon(Thalamus, Epithalamus, subthalamus)
Describe functions of diencephalon

Explain the neurotransmitters functioning in diencephalon
Explain the neuronal control of thalamic functions
NEU1 Phy9 : Organization, location and function of different descending pathways
Describe Upper/lower motor neuron.

Describe Pyramidal tracts, Basal nuclei &Basal ganglia.
NEU1 Phy10 : Motor, Vital and non-vital functions of Brain Stem
Describe medulla and pons

Explain Respiratory centers in medulla and pons with relation to Control of ventilation,
Describe medulla reticular formation,
Describe Control of respiration,Cough center, Sneeze center,Vomiting center.
Describe Cardiovascular centers, Baroreceptors,Vasomotor nerves,Arterial baroreceptors,
Describe Baroreceptor dysfunction
Explain Vasomotor control system
NEU1 Phy12 : Organization, location and function of different ascending pathways
Describe Sensory pathways and receptors.

Describe Spinothalamic pathway &Spinothalamic damage.
Describe Dorsal column pathway &Dorsal column damage.
DescrtibeSpinocerebellar pathway &Spinocerebellar tract damage.
NEU1 Phy13 : Physiology of pain
List the types of peripheral nerve fibers and receptor types that mediate nociception.
Explain the difference between pain and nociception.
Explain the differences between fast and slow pain and acute and chronic pain.
Explain hyperalgesia and allodynia.
280
NEU1 Phy16 : Basal ganglia and Disorders
Describe Functional anatomy of basal ganglia

Describe Components of basal ganglia
Explain Neuronal circuit of basal ganglia, Putamen circuit, Caudate circuit
List Specific neurotransmitter in basal ganglia
Describe Functions of basal ganglia
Explain Abnormalities of putamen and caudate circuit
Explain Disorders of basal ganglia
NEU1 Phy19 : CSF formation, circulation and functions

Explain Mechanism of formation & Absorption of CSF.
Give indication of CSF examination & lumbar puncture
NEU1 Phy20 : Functions of neurotransmitters
List two basic kinds of neurotransmitter.

Describe how synaptic activity regulates.
Describe different ways of manipulating neurotransmitters.
Describe Acetylcholine or Ach, Norepinephrine or NE, Dopamine or DA, Serotonin or 5HT,
Amino Acids &Neuromodulators:neuropeptide and gases.
NEU1 Phy22 : Reticular Activating System: Sleep and its disorders
Describe the sleep physiology

Describe the sleep types and various stages of sleep
Analyze the brain wave forms during different staged of sleep
Explain the effects of sleep deprivation
Explain the sleep disorders
281
PATHOLOGY
NEU1 Pth2 : Developmental anomalies of CNS
Recall the outlines of the development of CNS

Define the developmental anomalies of CNS
NEU1 Pth3 : Cerebral edema, Hydrocephalus, Raised intracranial pressure and herniation
Describe Cerebral edema

Describe Hydrocephalus
Describe Types of brain herniation
NEU1 Pth4 :Inflammation of brain and meninges
Describe the types, causes, morphology, complications &histopathological presentation

of meningitis, cerebral abscess, meningoencephalitis
NEU1 Pth5 : Mechanism of Ischemia Hypoxia, infarction and intracranial hemorrhage
Explain mechanism of Hypoxia and ischemia

Describe causes, Morphology of Hypoxia and ischemia
NEU1 Pth6 : Hypertensive cerebrovascular disease and intracranial hemorrhage
describe Types, Causes&Sequel of hemorrhages.
RADIOLOGY
NEU1 Rad1 : Radiology. CT scan and MRI of Spinal Cord
Name the radiologic modalities useful for evaluating spine

Identify gross radiologic anatomy of spine on CT and MR imaging
COMMUNITY MEDICINE
Endemic diseases involving Nervous System: Poliomyelitis, rabies, Diphtheria,
NEU1 Com1 :
Tetanus
Define endemic disease.
describe the differential diagnosis, causes, pathogenesis, diagnostic tools &
management of diseases involving nervous system.
282
NEU1 Com2 : Risk Factors Causing Stroke And Their Prevalence In Community
Give the WHOdefiniton of stroke

Classify the risk factors
Explain the prevalence of stroke in the western world .
Explain the prevalence of stroke in pakistan
enlist and communicate the prevention.
NEUROLOGY
NEU1 Neu1 : Approach to Neurologic patient
Perform general neurological examination of patient and take relevant history

Enlist manifestations of motor & sensory dysfunctions
Differentiate between upper & lower motor neuron lesion
Describe signs of extrapyramidal dysfunction
Define the patterns of weakness
NEU1 Neu2 : Screening Neurological Examination
Describe the concept of screening neurological examination

List the different components of screening neurological examination
NEU1 Neu3 : Electrophysiological investigation of neurological disorders (EEG & EMG/NCV)
Define EEG and describe the method of action and its clinical uses
Describe the different types of brain waves
Define EMG and describe the method of action and its clinical uses
NEU1 Neu4 : Gross clinical effects of territorial blockage of arteries
Describe clinical effects of arterial blockade of major arteries of brain.
283
BEHAVIORAL SCIENCES
NEU1 Beh1 : Perception
Describe the process of perception.

Describe different factors affecting perception.
Apply knowledge of perception in different clinical setting.
Describe different perceptual abilities and their practical application
NEU1 Beh2 : Thinking
Describe concept of thought process.

Describe different form of thinking.
Describe process of thinking in Problem Solving and decision making.
Describe concept of creative thinking.
Steps and barriers in creative thinking.
NEU1 Beh3 : Emotion
Describe the concept of emotions and its different types

Describe different theories of Emotions
Describe concept of positive and negative emotions
Describe clinical application of concept of emotions
Nervous System Module

I. INTRODUCTION TO CNS EXAMINATION
Diseases of nervous system are common and are an important cause of disability and deformity
both in adults and children. Nervous system examination is performed as an integral part of
physical examination, or when a patient presents with a neurological problem (for example:
headache, vertigo, seizure, stroke, numbness, muscular weakness, gait difficulty, speech
disorder).
Familiar with the correct method of nervous system examination.
284
CASE BASE LEARNIG
CBL 1:
Describe the blood supply of the brain and its meninges
Correlate different cortical areas according to motor functions
Define stroke and its causes
Correlate the clinical feature with the CT finding.
Elaborate the management plans for the given pathology
CBL 2
Identify the clinical signs & symptoms of raised intracranial pressure.

Correlate the clinical feature with the MRI finding.
Determine the type of lesion, primary or secondary.
CBL 3
Define Parkinsons disease and its signs and symptoms

Understand the pathophysiology of the given pathology
Describe tremors and its types
Differentiate between Parkinson disease and parkinsonism
CBL 4
Understand the pathways of different spinal tracts

Evaluate different levels of dissuasion of the spinal tracts
Describe pathologies related to the spinal tracts
Correlate spinal tract pathologies with the presenting symptoms
285
WEEKS/HOURS 1 2 3 4 5 6 7 T1 T1x100/T2 ROUND OFF
ANATOMY 9 7.5 10 4 7 4 37.5 29.29 30
BIOCHEMISTRY 1.5 1.5 - 4 2 4 - 13 10.15 10
PHYSIOLOGY 9 7 5 3 4 6 1 35 27.34 27
PATHOLOGY 1 1 - - 1 4 1 8 6.25 6
HISTOLOGY 2.5 1.5 1.5 1.5 1.5 - - 8.5 6.64 7
PHARMA - 1 - - 1 - 5 7 5.46 6
EMBRYOLOGY - - - 1 1 - - 2 1.56 1
COMMUNITY
- - 1 - 1 - - 2 1.56 1
MEDICINE
SKILL LAB - - 1.5 1.5 - - 3 2.34 2
RADIOLOGY - - - - - 1 - 1 0.78 1
NEUROLOGY - - - - - 1 4 5 3.90 4
CBL - 1.5 1.5 - 1.5 1.5 - 6 4.68 5
TOTAL 23 21 20.5 13.5 21.5 21.5 11 128 100 100
286
(SEMESTER-II)
SUMMATIVE ASSESMENT
THEORY

SEMESTER
EXAM
ATP 25
PAPER-I
20
based on CBL
Total 100
EMQs 10
MODULE
EXAM
ATP 20
MODULE PAPER
20
based on CBL
Total 100
STRUCTURED VIVA

ASSESMENT
SUMMATIVE
SEMESTER
EXAM
See Semester
Assessment Plan
ASSESMENT TOOLS
Structured Feedback
Facilitator
NOTE: Paper II & IV-B of Semester-3 Examination are Based on Head & Neck Module.
Paper III & IV-C of Semester-3 Examination are Based on Endocrinology Module.
287
CREDIT HOURS
SEMESTER II
Paper-I 6
Neurosciences
Paper-IV-A 3
288
HEAD & NECK & SPECIAL SCIENCES
CODE: HNN-1
Semester III
SECOND (2ND) YEAR M.B; B.S
289
Spiral Sem. Modules


Bones, Joints, Nerves & Muscles, 8 Week System 4 wks System4Week
Spiral
NEU1-Nervous System HNN1- Head & END1- Endocrinology
III 8 weeks Neck&Special 4 weeks
Senses 4 weeks
4 Week
wks
Second th
Spiral th
Trauma, 6 week
3 week 8 Weeks
/ Burns 2 wk
Weeks
th
th
PARALLEL THEMES:
290
MODULE COMMITTEE
Dr. Junaid Ashraf, Professor of Neurosurgery Dow Medical College, DUHS
Dr. Naheed khan, Associate Professor of Anatomy, DUHS
DrRukhsanaRubeen, Associate Professor of Biochemistry, DUHS
Dr , KelashAssociate Professor of Physiology, DUHS
Dr Rubina, Assistant Professor of Pathology, DUHS
Dr. Mohammad ShujaFarrukh, Associate Professor of ENT, DUHS
DrMuneerQuraishy,Associate professor of Eye, DUHS.
PARALLEL RUNNING SUBJECTS:

Capt. Dr. FarhatMirza, Professor ofForensic Medicine, DUHS (Forensic Medicine)
Dr. NighatNisar, Professor of Community Medicine, DUHS (Committee Medicine)
Dr. RazaurRehman, Professor of Psychiatry, DUHS (Behavioral Sciences)



Module committee
291
RATIONALE
Head and neck is a special region of the body where brain, spinal cord, organs of special senses
like eyes, ears, nose and the proximal alimentary and respiratory tracts exist in close proximity.
The anatomical relationships of these organs to each other are important to understand as
often diseases afflicting one of these also affect other organs by contiguity. Injuries to the region
of head, face & neck are associated with high mortality & morbidity. It is necessary to study this
region as a separate entity although it is not a separate system. This module provides the basic
understanding of the anatomy and physiology of the components of head and neck.
TERMINALOBJECTIVES
By the end of this module student will be able to:

Understand and describe the anatomy of structures of head and neck
Recognize the different special senses
Identify the histology of various organs in head & neck
Discuss the development of branchial arches
Describethe physiological mechanisms of all special senses
Describe the clinical significance of errors of refraction
Elaborate the histopathology of neoplastic lesions involving head and neck
292
LEARNING OBJECTIVES
methodology
BCQS, SEQS EMQS

DIGITAL LIBRARY
SELF STUDY
TUTORIALS
PRACTICAL
PRACTICAL
LECTURES
SKILL LAB
LIBRARY
VIVA
CBL
OBJECTIVES FACULTY TOPIC/CONTENT

t
Overview the head ANATOMY HNN1 Ang1:Overview the 1 * *

and neck regions. head and neck regions
PHYSIOLOGY HNN1 Phy1 : Overview of 1 * *
Special Senses
HNN1 Ang2 :Face 1 * *
(Muscles, Nerves: Extra
ANATOMY Cranial Part of V &VII
HNN1 Ang3 :Arteries & 1.5 * *
Veins of Face
Identify the HNN1 Ane1 1 * * *

derivatives of :Development of Face
pharyngeal arches
and pouches HNN1 Ane2 : 1.5 * * *
Development of Eye
HNN1 Ane3 1 * *
:Development of Ear
HNN1 Ane4 1.5 * * *

EMBRYOLOGY :Development of Nose &
Nasal Cavity
HNN1 Ane5 1 * *
:Development of
Pharyngeal Apparatus
HNN1 Ane6 :Derivatives 1 * *

of Pharyngeal arches &
Pharyngeal Pouches
(Tongue, Thyroid, Thymus
293
Identify the EMBRYOLOGY HNN1 Ane7 1.5 * * *
abnormalities of :Development of Soft and
pharyngeal arches Hard Palate & Congenital
and pouches Anomalies
Identify the features HNN1 Ang4 :Skull as a 1 * * *

of the vault & base whole and vault
of skull
ANATOMY HNN1 Ang5 1 *
:Pterygopalatine Fossa
Recognize the ANATOMY HNN1 Ang6 :Scalp (layers, 1 *

importance of scalp Nerves &Vessels
in the region of head
Identify the views of HNN1 Ang7 :Skull Norma 1.5 * *

skull frontalis
HNN1 Ang8 :Norma 1.5 * *

ANATOMY lateralis and occipitalis

Basalis
Anterior and middle part

Basalis
middle and posterior part
Enumerate the ANATOMY HNN1 Ang11 :Eyelids & 1 * *

contents of orbital lacrimal Apparatus
region &Ciliary Ganglion
HISTOLOGY HNN1 Anh1 :Histology of 1 * *
Eyelids, Conjunctiva,
Lacrimal Apparatus
HNN1 Ang12 :Orbital 1 * *

cavity (boundaries &
Extra-ocular muscles)
HNN1 Ang13 :Orbital 1
Cavity: Contents except
extraocular muscles
ANATOMY
294
Correlate the HISTOLOGY HNN1 Anh2 :Histology of 1.5 * * *
structures of eye Eye
with its functions.
HNN1 Phy2 :Formation & 1 * *
Circulation of Aqueous
Humor (Glaucoma)
PHYSIOLOGY HNN1 Phy3 :Photo 1 * * *
Transduction
BIOCHEMISTRY HNN1 Bio1 :Visual Cycle 1 * * *
HISTOLOGY HNN1 Anh3 :Eyelids & 1 * *

lacrimal Apparatus
HNN1 Phy4 : Visual acuity 1.5 * *
HNN1 Phy5 :Eye 1 * *

PHYSIOLOGY movements & their
control
HNN1 Phy6 :Field of 1.5 * *

Vision &Perimetery
Identify the HNN1 Phy7 :Visual Acuity 1 * * *

disorders of optical & Errors of Refraction
system at different PHYSIOLOGY
HNN1 Phy8 :Visual 1 * * *
levels
Pathway & its lesions
OPTHALMOLOGY HNN1 Oph1 :Errors of 1 * *

Refraction , presbyopia
& management
Explain the BIOCHEMISTRY HNN1 Bio2 :Vitamin A & 1 * *

biochemical its related Disorders
functions of vitamin
A and effects of
vitamin A deficiency
on vision
Describe the major HISTOLOGY HNN1 Anh4 :Salivary 1.5 * * *
and minor salivary Glands
glands
PATHOLOGY HNN1 Pth1 1.5 * * *
:Inflammatory, neoplastic
and non- neoplastic
lesions of salivary glands
295
Enumerate the HNN1 Ang14 :Temporal 1 * *
structures of the Region &Temporo
temporal region ANATOMY mandibular Joint
HNN1 Ang15 1.5 * *

:Infratemporal Fossa & its
contents (including
muscles of mastication
Recognize the HNN1 Ang16 :Mandible 1 * *

importance of
mandibular region in ANATOMY HNN1 Ang17 :Parotid 1 * *
the face of an Region
individual
Identify the ANATOMY HNN1 Ang18 :External 1 * *
structures of ear & Ear (Pinna & External
histological features Meatus)
of ear Middle Ear Cavity & its
Contents
Identify the parts of HNN1 Phy9 :Sense of 1 * *
auditory pathway Hearing, its mechanism
and describe the and auditory pathway
mechanism of
transmission of
sound PHYSIOLOGY HNN1 Phy10 :Hearing 1 * *
Conduction Test
HNN1 Phy11 :Disorders of 1 * *

hearing
Describe mechanism PHYSIOLOGY HNN1 Phy12 :Mechanism 1 * *

of balance how of Balance and related
the body regulate disorders
balance
Identify the HNN1 Ang19 :External 1 * *

structures of Nose & Bony Boundaries
nose&Para-nasal of Nasal Cavity
Sinuses
HNN1 Ang20 :Para-nasal 1.5 * * *
ANATOMY
Sinuses
HNN1 Ang21 :Nerves & 1.5 * * *
Blood Vessels of Nose &
Nasal Cavity
HISTOLOGY HNN1 Anh5 :Nasal Cavity 1.5 * *
Respiratory & Olfactory
Epithelium
Identify the HNN1 Ang22 :Hard and 1 * *

structure and soft palate
296
function of oral ANATOMY HNN1 Ang23 :Oral Cavity 1 * *
cavity &related
disorders
HISTOLOGY HNN1 Anh6 :Oral Cavity 1.5 *
PATHOLOGY HNN1 Pth2 :Tumor and 1

Precancerous conditions
of Oral cavity
Describe sense of PHYSIOLOGY HNN1 Phy13 :Sense of

olfaction with Olfaction: its receptor &
relation to pathway
anatomical & ANATOMY HNN1 Ang24 :Tongue +
biochemical function Hypoglossal Nerve
of related structures
HISTOLOGY HNN1 Anh7 :Tongue
Describe the deep ANATOMY HNN1 Ang25 :Deep 1 * *

structures in the Cervical Fascia &Platysma
neck.
Enumerate 12 OPTHALMOLOGY HNN1 Oph2 :Cranial 1 * * *

cranial nerves nerve palsy affecting the
Explain clinical eye and pupillary
effects of injury to disorder
each cranial nerve ANATOMY HNN1 Ang26 :Vestibulo- 1 * * *
cochlear Nerves &
Intracranial Part of facial
nerve
BEHAVIORAL HNN1 Beh1 :Motivation 1 * *
SCIENCES
HNN1 Beh2 : Intelligence 1 * *
/cognition
BEHAVIORAL
SCIENCES
HNN1 Beh3 : Memory 1 * *
297
Head & Neck and Special Sciences Module
Time Table
First Week
Days 08:30 to 10:00 10:30 to 11:30 11:30 to 12:30 1:30 to 03:00
1
CNS MODULE TEST
Anatomy
Scalp (layers, Anatomy Anatomy Demonstration:
Anatomy demonstration (5 batches) Nerves &Vessels Skull Norma frontalis (5Batches)
2 Skull as a whole and vault
Name of Norma lateralis and occipitalis
Name of faculty Venue Name of faculty Venue Name of faculty Venue
faculty Venue
BEHAVIORAL SCIENCES
BEHAVIORAL SCIENCES
Intelligence SELF STUDY
3 Motivation
Name of faculty Venue Name of faculty Venue
4 PUBLIC HOLIDAY
Anatomy
Histology
Eyelids & lacrimal Anatomy Demonstration
Anatomy Demo 5 batches Of Eyelids, Conjunctiva,
Apparatus &Ciliary 5 batches
Face (Muscles, Nerves: Extra Cranial
5 Ganglion Lacrimal Apparatus Norma Basalis
Part of V &VII)
Anterior and middle part
Name of faculty Venue Name of faculty Name of faculty
Venue Name of faculty Venue
Venue
298
Head & Neck and Special Senses
TIME TABLE SEMESTER III, Week 2
Days 08:30 to 10:00 10:30 to 11:30 11:30 to 12:30 01:30 to 03:00
ANATOMY EMBRYOLOGY PHYSIOLOGY ANATOMY DEMO

(Arteries & Veins of Face Development of Face Overview of Special 5 batches
1 Name of faculty Senses Norma Basalis
Name of faculty Venue Name of faculty middle and posterior part
Venue
1.=Self Study GP:A

PHYSIOLOGY 2.=Physiology Practical GP:B
GROSS ANATOMY and PHYSIOLOGY Visual acuity Name of faculty
Formation & Circulation
Histology of of Aqueous Humor Visual Acuity & Errors 3=Histology
Venue H) Practical
2 Eye (Glaucoma of Refraction Eyelids & lacrimal Apparatus GP
Name of faculty Venue Name of faculty Name of faculty C(DR.RIAZ)
Venue Venue 4: Cbl GP D
5.Skill lab CNS examination :
GP:E1Gp: E2 SELF STUDY
ANATOMY 1.B
PHYSIOLOGY EMBRYOLOGY
Development of Eye 2.C
Orbital cavity (boundaries & Photo Transduction
3
Extra-ocular muscles) Name of faculty 3.D
Name of faculty 4.E
Name of faculty Venue Venue Venue
5.A
ANATOMY PHYSIOLOGY 1.C

BIOCHEMISTRY
Visual Pathway & its Vitamin A & its related 2.D
Orbital Cavity: Contents except lesions Disorders
4
extraocular muscles
3.E
Name of faculty Name of faculty 4.A
Name of faculty Venue Venue Venue 5.B
8:30-10:00
1.D
10:30-12:00
2.E ANATOMY
5 External Nose & Bony Boundaries of Nasal Cavity
3.A
4.B Name of faculty Venue
5.C
CLINICAL FACULTY
ANATOMY Cranial nerve palsy 1.E
BIOCHEMISTRY
Visual Cycle affecting the eye and 2.A
6 Para-nasal Sinuses pupillary disorder 3.B
Name of faculty Venue Name of faculty
Name of faculty 4.C
Venue 5.D
Venue
299
TIME TABLE SEMESTER III
Week 3
Days 08:30 to 10:00 10:30-11:30 11:30to 12:30 01:30 to 03:00
1=Physiology Tutorial
Eye movements & their
controlGP:A: Name of faculty
Clinical faculty Venue
(eye)
Anatomy 2=Physiology Practical
Errors of Refraction
Nerves & Blood Vessels of Nose Gross anatomy Field of Vision &Perimetery
, presbyopia & Lecture
1 & Nasal Cavity management
Name of faculty Venue GP:B
Mandible
Name of faculty Venue 3=Histology Practical Eye Name
Name of faculty Name of faculty Venue
of faculty VenueGP:C
Venue
4=Skill lab CNS examination
GP:D2
GP:D1 : SELF STUDY
5=SELF STUDY GP:E
2 Public Holiday
1.B
Histology Embryology 2.C
Physiology
Nasal Cavity Development of Nose 3.D
Respiratory & Olfactory Sense of Olfaction: its receptor &
3 & Nasal Cavity 4.E
pathway
Epithelium Name of faculty 5.A
Name of faculty Venue Venue2 Name of faculty Venue
Anatomy 1.C
External Ear (Pinna & External Histology 2.D
Anatomy 3.E
Salivary Glands
Meatus) Gross Anatomy
4 Name of faculty 4.A
Middle Ear Cavity & its Parotid Region 5.B
Contents Venue Name of faculty Venue
Name of faculty Venue
1.D 10:30-12:00
2.E
Anatomy Lecture
3.A
5 VestibulocochlearNerves&Intracranial Part of facial nerve
4.B
5.C Name of faculty Venue
Anatomy 1.E
Embryology Physiology 2.A
Gross Anatomy Development of Ear Sense of Hearing, its mechanism 3.B
6 Temporal Region
&Temporomandibular Joint Name of faculty and auditory pathway 4.C
Name of faculty Venue Venue Name of faculty Venue 5.D
300
TIME TABLE SEMESTER III
Week 4
DAY 08:30 TO 10.00 10:30 TO 11:30
S
11:30 TO 12:30 1:30 TO 03:00
1, Physiology Practical GP A
Hearing Conduction Test
Revisit Gross Anatomy Demo 5batches Name of faculty Venue
+HISTOLOGY Embryology 2 Self Study Gp B
Gross Anatomy
External, middle And Development of Ear 3, Histology Practical Salivary
1 Temporal Region
Internal Ear Name of faculty GlandsGpC Name of faculty
&Temporomandibular Joint Venue
Name of faculty Venue Venue
4CBL Gp D
5 Self studyGpE
ANATOMY PHYSIOLOGY
Mechanism of 1. B
Infratemporal Fossa & its PHYSIOLOGY 2. C
contents(including muscles Disorders of hearing Balance
2
and related disorders 3. D
of mastication Name of faculty Venue 4. E
5. A
Venue
PATHOLOGY 1.C
EMBRYOLOGY
ANATOMY Inflammatory, 2.D
Development of Pharyngeal
3 Pterygopalatine Fossa neoplastic and non- 3.E
Apparatus
Name of faculty Venue neoplastic lesions of 4.A
Name of faculty Venue salivary 5.B
glandsName of
faculty Venue
HISTOLOGY 1.D
ANATOMY DEMO GROSS ANATOMY
Oral Cavity 2.E
4 Hard and soft palate Oral Cavity
Name of faculty 3.A
Name of faculty Venue Name of faculty Venue 4.B
Venue
5.C
10:00-11:00 11:00- 12:00
ANATOMY DEMO EMBRYOLOGY PATHOLOGY
Tongue + Hypoglossal Nerve Derivatives of Pharyngeal Tumor and Precancerous
5 Anatomy arches & Pharyngeal conditions ofOral cavity
Name of faculty Venue Pouches (Tongue, Thyroid,
Thymus Name of Name of faculty
faculty Venue Venue
EMBRYOLOGY
Development of Soft 1.E
GROSS ANATOMY HISTOLOGY and Hard Palate & 2.A
Deep Cervical Fascia Tongue 3.B
6 Congenital
&Platysma Name of faculty Venue 4.C
Anomalies
Name of faculty Venue Name of faculty 5.D
Venue
301
TIME TABLE SEMESTER III, Week 5
Days 8.30-10:00 10.30-11.30 11.30-12.30 1.30-3.00
Anatomy Demo
Posterior Triangle Physiology
Sense of Taste, its ANATOMY ANATOMY
(Trapizeus& Anterior Triangle of Neck + Prevertebral&Scaleni
Sternocleidomastoid receptors and its
1 pathway Supra and Infra Hyoid Muscles Muscles + root of neck
muscles) Cervical Name of faculty Venue Name of faculty
Plexus & Accessory Name of faculty
Venue Venue
Nerve Name of
faculty Venue
1.Anatomy demo Gp:A
Cervical vertebrae Name
of faculty Venue
Histology of Gross Anatomy 2. Histology PRACTICAL
Gross Anatomy Thyroid and Para Thyroid
Thyroid & ANATOMY 5groups
Thyroid Gland glands Gp:B Name of
2 Parathyroid Submandibular Region
Name of faculty faculty Venue
Venue
Venue 3. CBL Gp: C
4. Gp: SELF STUDY D
5.SELF STUDY Gp: E
Gross Anatomy Gross Anatomy Gross anatomy 1.B

Carotid arteries + veins and lymph 2.C
nodes of head and ANATOMY 3.D
3 Carotid Sheath Pharynx Including tonsils
neck 4.E
Name of faculty 5.A
Venue
Venue
Physiology Gross Anatomy 1.C
Mechanism of Lesions of Cranial ANATOMY 2.D
4 swallowing Nerves Glosspharyngeal and Vagus nerves 3.E
Name of faculty 1---6TH Name of faculty Venue 4.A
Venue Name of faculty 5.B
Venue 1D
Gross Anatomy
Lesions of Cranial Nerve 2E
5 7TH----12TH 3A
4B
Name of faculty Venue 5C
BEHAVIORAL ANATOMY 5groups 1. E
Pathology
Neoplastic lesions of SCIENCES Gross anatomy of Larynx 2. A
head and neck Name of faculty Venue 3.B
6 memory
4.C
Name of faculty Name of faculty 5. D
Venue Venue
302
LEARNING OBJECTIVES
objectives:
ANATOMY
HNN1 Ang1 : Overview the head and neck regions
Explain the overview of neck regions

Explain the overview of head surface,muscle, innervations, blood & venous supply
HNN1 Ang2 : Face (Muscles, Nerves: Extra Cranial Part of V &VII
Describe the boundaries of face

Enumerate the muscles and innervations of face
Describe the blood supply of face
Describe the disorders and applied of face
HNN1 Ang3 : Arteries & Veins of Face
Describe arterial supply of head and neck, including:

External carotid artery origin and supply,
Maxillary artery origin and supply,
Facial artery origin and supply,
Lingual artery origin and supply,
Internal carotid artery origin
Major venous drainage to sinuses,
Head and neck major veins.
HNN1 Ang4 : Skull as a whole and vault
Define axial skeleton

describe bones of skull and cranium
explain overview of Skull Geography &Sutures
Differentiate the various views of the skull
HNN1 Ang6 : Scalp (layers, Nerves &Vessels)
Explain the extent of scalp

Describe five layers of scalp
303
Identifythe nerves and vessels of scalp
Enumerate the clinical correlates
HNN1 Ang7 : Skull Norma frontalis
Define norma frontalis

Explain the different regions of it
Enumerate the muscle attachment
Describe Boundries and features of its structure.
HNN1 Ang8 : Norma lateralis and occipitalis
Enlist various bones in normal lateralis

Describe the Cranial and facial subdivisions
Define External acoustic meatus
HNN1 Ang9 : Norma BasalisAnterior and middle part
Describe bones forming the base of skull

Explain the details of anterior, middle and posterior part of base ofskull
Identify different foramina and structures passing through them atthe base
Explain the attachments and relations of base of skull
HNN1 Ang10 : Norma Basalis, middle and posterior part
Describe bones forming the base of skull

Explain the details of middle and posterior part of base ofskull
Identify different foramina and structures passing through them atthe base
Explain the attachments and relations of base of skull
HNN1 Ang11 : Eyelids & lacrimal Apparatus & Ciliary Ganglion
Describe the palpebarel fissure

Explain the different layers of the eyelid and its muscles.
Enumerate the blood supply and innervations of eyelids.
Illustrate lacrimal apparatus ciliary ganglion and tfeir disprders.
304
HNN1 Ang12 : Orbital cavity (boundaries & Extra-ocular muscles)
Describe the boundaries of the orbit

Explainthe relations of optic fascia
Explain the muscles and their innervations
HNN1 Ang13 : Orbital Cavity: Contents except extraocular muscles
Describe the foramina of orbital cavity with their contents.

Explain the structures supplied by nerves of orbital cavity.
Describe the blood vessels of orbit.
HNN1 Ang14 : Temporal Region & Temporo mandibular Joint
Describe the boundaries and contents of temporal fossa.

Enumerate the temporomandibular joint,its type,formation,neurovascular
supply and action.
Clinically correlate disorders of the temporo mandibular joint.
HNN1 Ang15 : Infratemporal Fossa & its contents (including muscles of mastication)
Explain the submandibular region.

Describe the anterior triangle of the neck.
Listthe Suprahyoid muscles.
Describe the submandibular gland.
Describe the sublingual gland.
Define what is submandibular ganglion
HNN1 Ang16 : Mandible
Define Location of mandible

Describe Parts of mandible
Explain Structural features of each part
Enlist Attachments of each part
Describe Blood and nerve supply of mandible
Interpret Applied anatomy of mandible
HNN1 Ang18 : External Ear (Pinna & External Meatus), Middle Ear Cavity & its Contents
Describe Parts of ear.
Explain functions of middle, internal ear.
Explain of organ of hearing and balance.
305
Interpret Applied anatomy of ear
HNN1 Ang19 : External Nose & Bony Boundaries of Nasal Cavity
Describe the anatomy of external nose.

Define the Boundaries of nasal cavity.
Explain Blood vessels of nose.
Enumerate Nerve supply of nose.
HNN1 Ang20 : Para-nasal Sinuses
Define & list names of paranasal sinuses

Describe functions of paranasal sinuses.
Identify Radiographic Protocols for sinuses
Explain diseases of sinuses.
HNN1 Ang21 : Nerves & Blood Vessels of Nose & Nasal Cavity
Identify & DescribeArterial&Venous supply of nose and nasal cavity.

Describe Nerve supply of nose and nasal cavity
HNN1 Ang22 : Hard and soft palate
Describe the palate and its types.

Describe the hard palate.
Listmuscles of the soft palate.
Describe the vasculature and innervation of the palate.
HNN1 Ang23: Oral Cavity
Define the boundaries of oral cavity

Describe Structures forming the roof ,lateral walls and floor of oral cavity.
Enumerate Nervous supply of oral cavity.
HNN1 Ang24 : Tongue + Hypoglossal Nerve
Describe what is tongue and Pailla.

Explain taste buds andIsthimus faucium
Enumerate the Extrinsic andIntrinsic muscles of the tongue
Define functions of Hypoglossal nerve and Glossopharyngeal nerve.
306
HNN1 Ang25 : Deep Cervical Fascia & Platysma
Describe what is deep cervical fascia

Explain the investing layer of deep cervical fascia and the structure it encloses.
Define attachment of the fascia.
Enlist the four parts namely: the investing layer, pretrachial fascia, prevertebral
fascia &the carotid sheath
HNN1 Ang26 : Vestibulo-cochlear Nerves & Intracranial Part of facial nerve
Define vestibulocochlear nerve.

Explain the components & structure and function of this nerve.
Describe its attachment to the brain stem & its course through the cranial cavity.
Describe its innervations & symptoms of damage like hearing loss , vertigo,
nystagmus, motion sickness, false sense of motion, loss of equilibrium (in dark
places), gaze-evoked tinnitus.
Interpret related applied anatomy.
Describe intracranial part of facial nerve.
EMBRYOLOGY
HNN1 Ane1 : Development of Face
Describe the Developmental stages of Face

Explain the congenital Anomalies of face
HNN1 Ane2 : Development of Eye
Describe the steps of development of human eye.

Explain the derivatives of different embryonic primitive eye layers.
Describe the development of various layers of eye individually, along with optic
nerve.
HNN1 Ane3 : Development of Ear
Explain development of inner ear.

Describe development of middle ear.
Elaborate development of external ear.
307
HNN1 Ane4 : Development of Nose & Nasal Cavity
Explain developmental stages of nose.

Describe development of nasal cavity.
Explain development of paranasal sinuses.
Explain congenital anomalies of nose and nasal cavity.
HNN1 Ane5 : Development of Pharyngeal Apparatus
Define pharyngeal Apparatus

Describe development of pharyngeal Apparatus
List the different Parts of pharyngeal Apparatus
Explain fate of pharyngeal Arch and pharyngeal Cleft
Explain fate of pharyngeal Pouch and pharyngeal Membrane
Describe the Congenital Anomalies related to pharyngeal Apparatus.
HNN1 Ane6 : Derivatives of Pharyngeal arches & Pharyngeal Pouches (Tongue, Thyroid, Thymus
DefineBranchial Apparatus
Describe Development of Branchial Apparatus
Enlist the different Parts of Branchial Apparatus
describe Fate of Branchial Arch, Branchial Cleft, Branchial Pouch &Branchial Membrane
HISTOLOGY
HNN1 Anh1 : Histology of Eyelids, Conjunctiva, Lacrimal Apparatus
Describe eye, Sclera and its walls,

Interpret Choroid and its walls,
DescribeCiliary body,
Explain Aqueous humor,Iris andVitreous body.
HNN1 Anh2 : Histology of Eye
Describe Retina development,Layers of retina,

Explain Functions of retinal pigment epithelium,
Define Neuronal retina,three deep neurons.
Evaluate Photoreceptors and Rod cells.
HNN1 Anh4 : Salivary Glands
Describe Salivary glands and their location

DescribeHistology of parotid gland
DescribeHistology of submandibular gland
DescribeHistology of sublingual gland.
308
HNN1 Anh6 : Oral Cavity
Describe the different parts of oral cavity.

Explain the histology of these different parts of oral cavity
Distinguish the location and histological similarities and dissimilarities among the
different types of oral mucosae.
BIOCHEMISTRY
HNN1 Bio1 : Visual Cycle
Describe visual cycle.

Enumerate different steps for the formation of visual complex.
Explainthe role of retinaldehyde in vision.
HNN1 Bio2 : Vitamin A & its related Disorders
DescribeStructure& Forms of vitamin A.

Illustrate Storage and transport of vitamin A.
Enlist Functions of vitamin A.
Explain Disorders of Vitamin A deficiency.
PHYSIOLOGY
HNN1 Phy1 : Overview of Special Senses
Describe the structures of the Special Senses

Explain the pathways of sound in the ear and light in the eye
Identify, describe, and discuss the receptors and neural pathways involved in each of
the five special senses.
HNN1 Phy2 : Formation & Circulation of Aqueous Humor (Glaucoma)
Describe aqueous humor and its function

Explain Its composition, formation and circulation&outflow
Describe Intraocular pressure , glaucoma its various types and detection
HNN1 Phy3 : Photo Transduction
Define Photo transduction.

Explain the photoreceptor cells involved in photo transduction.
309
Enumerate the photopigments.
Describe the steps involved in photo-transduction.
HNN1 Phy5 : Eye movements & their control
Describe the movements of the eyes and how it works

Explain the functions of extra-ocular muscles in the movement
Describe the innervations in the eye movement
HNN1 Phy6 : Field of Vision &Perimetery
To plot the field of Vision by Perimeter.
HNN1 Phy7 : Visual Acuity & Errors of Refraction
Describe visual acuity,

ExplainSnellen chart,
Describe normal vision, normal visual acuity and other measures of visual acuity,
Distinguish Refractive errors, causes of refractive errors,
Explain management of the refractive errors
HNN1 Phy8 : Visual Pathway & its lesions
Define what is visual system

Enlist the constituents of visual system
Describe Optic pathway and its lesions
HNN1 Phy9 : Sense of Hearing, its mechanism and auditory pathway
Describe the components and functions of the external, middle, and inner ear.
Define the sound stimulus.
Explain the parts of the inner ear and their roles in equilibrium and hearing.
Interpret auditory Physiology.
Describethe pathways for the sensations of hearing.
HNN1 Phy11 : Disorders of hearing
Describe Hearing disorders,& types of hearing disorders,

Identify according to Functional classification, causes of middle ear disorders,
Define & describe cholesteatoma
310
Explain sensorineural disorders
HNN1 Phy12 : Mechanism of Balance and related disorders
Explain overview of vestibular system.

Describe Vestibular apparatus, vestibule and cochlea,
Explain Vestibular receptor sense organs and detected stimuli and otolith organ.
Explain Depolarization of hair cells, macular hair cells in utricle
Describe Semicircular canal, push pull activation of semicircular canals, CNS vertebral
connections,
Identify Central connections of the vestibular system(cell bodies in vertebral
ganglion),Vertebral reflexes.
Describe nystagmus, vertebral disease and S/S of vertebral disease
HNN1 Phy13 : Sense of Olfaction: its receptor & pathway
Define what is taste.

Describe taste buds and its structure.
Explain taste sensations.
Enlist types of papillae.
Enumerate taste pathway.
PATHOLOGY
HNN1 Pth1 :Inflammatory, neoplastic and non- neoplastic lesions of salivary glands
Explainetiology, pathogenesis, contributing factors, and major subtypes of

Inflammatory, non-neoplastic and neoplastic lesions of salivary glands
Explainetiology, pathogenesis, contributing factors, and major subtypes of Tumor and
Precancerous conditions of oral cavity
HNN1 Pth2 : Tumor and Precancerous conditions of Oral cavity
Explainetiology, pathogenesis, contributing factors, and major subtypes of Caries,

gingivitis, reactive nodules, infections of oral cavity
Explainetiology, pathogenesis, contributing factors, and major subtypes of Neoplastic
lesions of head and neck
311
OPTHALMOLOGY
HNN1 Oph1 : Errors of Refraction, presbyopia & management
Define & Describe Refractive Errors, Emmetropia, Hypermetropia, Astigmatism

Define & describe accomodation
HNN1 Oph2 : Cranial nerve palsy affecting the eye and pupillary disorder
Describe Distribution of cranial nerves

Explain Functional classification of cranial nerves, their pathways
Explain Clinical features related to the disorders
BEHAVIORAL SCIENCES
HNN1 Beh1 : Motivation
Describe concept of motivation

Differentiate among different types of Motivation
Differentiate between biological and psychological and social motives
Describe steps of Psychological mechanism of motivation.
Describe different staged of Abraham Maslows hierarchy of needs.
Describe clinical application of motivation
HNN1 Beh2 : Intelligence /cognition
Describe concept of intelligence

Describe different Mental Abilities / Proficiencies (intellectual Attributes)
Describe Ganders concept of multiple intelligence and contemporary theories of
intelligence
Describe the concept of emotional Intelligence
Describe role of genetics and environment in development of Intelligence
Describe the use of Intelligence Test
HNN1 Beh3 : Memory
Analyze the concept of memory

Differentiate between different types of Memory
Describe different stages in development of memory.
Critically review the role of anatomy of biochemistry in formation of Memory
Use methods to improve memory
Analyze the memory problem in pathological conditions.
312
Head and Neck and Special senses Module:
II. Introduction to Cranial Nerves Examination

Introduction/ Rationale:
Examination of the function of the cranial nerves is an important part of the neurological
assessment. All the cranial nerves may be involved in disease processes in their intracranial and
extra cranial courses and at their site of origin within the brain and brainstem.
Learning objectives:
Demonstrate the correct method of examination of cranial nerves 2nd, 3rd, 4th, 6th and 7th
CASE BASED LEARNING

HNN 1CBL 1
Define Parkinsons disease and its signs and symptoms
Understand the pathophysiology of the given pathology
Describe tremors and its types
Differentiate between Parkinson disease and parkinsonism
HNN 1CBL 2
Describe the blood supply of the brain and its meninges
Correlate different cortical areas according to motor functions
Define stroke and its causes
Correlate the clinical feature with the CT finding.
Elaborate the management plans for the given pathology
HNN 1CBL 3
Identify the clinical signs & symptoms of raised intracranial pressure.
Correlate the clinical feature with the MRI finding.
Determine the type of lesion, primary or secondary.
313
WEEKS/HOURS 1 2 3 4 5 T1 T1x100/T2 ROUND OFF
ANATOMY 17 9 5 9 15 55 52.63 52
BIOCHEMISTRY 1 1 - - - 2 1.91 2
PHYSIOLOGY 6 4 4 2.5 2.5 19 18.18 18
PATHOLOGY - - 1 1.5 1.5 4 3.82 4
HISTOLOGY - 3.5 - 3.5 2.5 9.5 9.09 9
EMBRYOLOGY 2 1 1 2.5 1 7.5 7.18 7
RADIOLOGY - - - 1 - 1 0.95 1
EYE-CLINICAL
- 1 1 - - 2 1.91 2
FACULTY
CBL - 1.5 - 1.5 1.5 4.5 4.30 4
TOTAL 26 21 12 21.5 24 104.5 100 100
314
BLUEPRINT OF ASSESSMENT
HEAD & NECK MODULE
(SEMESTER-III)
SUMMATIVE ASSESMENT
THEORY

SEMESTER
ATP 25
EXAM

20
based on CBL
80%
Total 100
MODULE EXAM
EMQs 10
ATP 20
MODULE PAPER
20
based on CBL
Total 100
STRUCTURED VIVA

ASSESMENT
SUMMATIVE
SEMESTER
EXAM
See Semester
Assessment Plan
ASSESMENT TOOLS
Structured Feedback
Facilitator
NOTE: Paper I & IV-A of Semester 2 Examination are Based on NeurosciencesModule.

Paper III & IV-C of Semester 2 Examination are Based on Endocrine Module.
315
CREDIT HOURS
SEMESTER III
HEAD & NECK & SPECIAL SENSES-1 MODULE
Paper-II 3
HNN-1
Paper-IV B 1.5
316
ENDOCRINOLOGY MODULE I
Code: END 1
Semester III
Second Year MBBS
317
Spiral Sem. Modules

II

4 Week
wks
Second th
Spiral th
Trauma, 6 week
3 week 8 Weeks
/ Burns 2 wk
2 Weeks
th
th
PARALLEL THEMES:
318
ENDOCRINOLOGY MODULE COMMITTEE
Dr.Rubina Gulzar (Asstt.Professor of Pathology DMC)
Dr.Tahseen (Asstt.Professor of Biochemistry DMC)
Dr.Mujtaba (Associate Professor of Anatomy DMC)
Dr.Fuad Shaikh (Senior Lecturer of Pharmacology DMC)
Dr. Kelash (Associate Professor of Physiology DMC)
Dr.Akhtar Baloch,Assisstant Professor of Medicine,DMC,CHK
Dr.Muzzamil Shabana Ejaz,Assisstant professor of Paediatrics, DMC,CHK
Prepared by :
Dr.Ateeba Ayesha Khan
Coordinated by:
Reviewed by:
Module Committee
319
RATIONALE
The function of the endocrine system is to coordinate and integrate cellular activity
within the whole body by regulating cellular and organ function throughout life
and maintaining homeostasis. Homeostasis, or the maintenance of a constant
internal environment, is critical to ensuring appropriate cellular function. In this
module the anatomy and physiology of the endocrine organs alongwith functional
biochemistry of the hormones secreted alongwith normal physiological changes are
taught in integrated fashion with reference to common disease processes occurring
in our community.
TERMINAL OBJECTIVE
By the end of this module student will be able to:
Review the anatomy of endocrine organs (pituitary, thyroid, pancreas,

parathyroid and adrenal gland).
Describe the role of hormones in relation to homeostasis and metabolism.
Identify and list functional physiology of hormones.
Recognize stepwise synthesis and release of various hormones
Enlist common endocrine related disorders and their pathogenesis
Recognize various endocrine disorders on the basis of clinical and
investigative findings
Highlight the role of pharmacological agents used to treat endocrine
disorders
320

modes of information transfer, duration of teaching of each content and the
mode of assessment.
Self Study
Practical /
One Best,
CBL / SBL
Tutorials
Practical
Lectures
spotting
Skills Lab
Demo:
EMQS
viva
Assesment
Objectives Modes of information transfer
Physiology END1 Phy1 * *
1
Introduction of
Endocrinology,
Control and
feedback
Overview of all Anatomy * *
endocrine glands / END1Ang1
Describe the
Anatomical 1.5 1.5
development, gross
overview of all
and microscopic endocrine glands in
features and List the body (Gross)
the endocrine
glands in the body
with their
respective
hormones
Classify the Biochemistry * * *

hormones on the
basis of structure, END1 Bio1
1
biochemistry and
Classification of
functions
hormones based on
chemical structure
and Mechanism of
action
321
Anatomy END1 Ang2 1 * *
Describe the
development, Gross structure of
biochemical hypothalamus
structure,
secretions, mode of Physiology END1Phy2 * * *
action, functions, 1.5
Hypothalamus and
anomalies and
common related Ant: Pituitary
disorders of Hormones
hypothalamus Anatomy END1Ang3 * *
Gross, and 1.5
development of
Pituitary(
demonstration)
Anatomy END1 Anh1 * *

1 1.5
Microscopic
structure of
Pituitary
Pathology * * *
END1 Pth1
Anterior pituitary
and 1.5
Posterior pituitary
Medicine 1 * *
END1 Med1
Clinical disorders of
pituitary
END1 Phy3 1.5 *
Disorders of Ant.
Pituitary
END1Phy4 * *
1
Growth hormone
Synthesis, function
& related disorders
END1Phy5 * *
Physiology
Hormones of the
posterior pituitary 1
and related
disorders (Function
of Posterior
Pituitary Hormones
& diabetes insipid
us )
322
Biochem END1 Bio2 1.5 * *
Molecular
structure and
biochemical
functions of
Anterior Pituitary
Hormones
CBL END1 Cbl1 1.5 * *
Acromegaly
Describe the END1 Ang4 1.5 * *

development,
biochemical Demonstration:
Gross structure of
structure,
thyroid and
secretions, mode of parathyroid
action, functions, Anatomy END1 Anh 2 1 1.5 * * *
anomalies and
common related Microscopic
disorders of thyroid structure of
and parathyroid thyroid and
parathyroid
gland
1 * *
END1 Ane2
Development of
Thyroid and
parathyroid and
related anomalies
1 * *
END1 Bio3
Thyroid: Synthesis
mode of action,
metabolic
functions
END1 Bio4 * *
T3, T4, TSH iodine 1.5
levels, Long acting
Biochemistry thyroid Stimulator
(Lab investigation
for thyroid
functions)
1.5 * *
END1 Bio5
Parathyroid
hormone,
Calcitonin and
related disorders
Medicine 1.5 * *
END1 Med2
323
Presentations of
Hypothyroidism /
Hyperthyroidism
and Interpretation
of laboratory
CBL 1.5 * *
END1 Cbl 2
Graves disease
(hyperthyroidism)
1.5 * *
END1 Phy6
Function of Thyroid
Hormones
END1 Phy 7 1 * *
Function of
Parathyroid
Physiology
Hormones
END 1 Phy 8 1.5 * *
Physiology
Practical: Thyroid
function Test &
BMR
Pharmacology END1 Pha 1 1 * *
Drugs used in hypo
and
hyperthyroidism
1 * *
END1 Pha 2
Drugs used in hypo

and hypercalcemia
Pathology 1 * *
END1 Pth2
Hypothyroidism
1.5 * *
END1 Pth3
Disorders of
parathyroid gland
1.5 * *
END1 Pth4
Hyperthyroidism
and graves disease
Discuss the Com. Med. 1 * *
epidemiology and END1 Com1
consequences of
Iodine Control
iodine deficiency
Program
and the salient
features of iodine
control program in
Pakistan
324
Describe the * *
development, END1 Ang5 1.5
structure,
secretions, mode of Gross structure of
action, functions, pancrease
anomalies and
common related 1 * *
disorders of END1 Anh3
pancreas.
Microscopic
structure of
pancreas
1.5 * *
Anatomy END1 Ane3
Development of
pancreae
1.5 * *
END1 Anh4
Microscopic
structure of
pancreas
* *
END1 Phy9 1.5
Hormonal secretion
of Pancreas
Glucagon,
somatostatin)
Physiology
1 * *
END1 Phy10
Hormonal secretion
of pancrease
(insulin)
1 * *
END1 Bio4
Endocrine
secretions of
Pancreas,
molecular structure
and biochemical
function ( insulin)
1.5 * *
END1 Bio5
Biochemical
interpretation for
the diagnosis of
Diabetes mellitus.
325
1 * *
END1 Bio6
Endocrine
secretions of
Biochemistry Pancreas,
molecular structure
and biochemical
function (Glucagon,
somatostatin)
END1 Bio7 * *
Regulation of blood 1
glucose level, hyper
and hypoglycemia.
Complications of
Diabetes Mellitus
e.g. Diabetic Keto-
acidosis and
nonketotic
complications.
CBL END1 Cbl 3 1.5 * *
Diabetes mallitus
Given a set of 1 * *
laboratory data, END1 Pth5
differentiate
between hypo and Diabetes
hyper secretion of Pathogenesis
Pancreas
* *
END1 Pth6 1
Pathology Diabetes
Complication
Describe * *
integration of 1
different hormones END1 Pha2
in growth,
Oral Hypoglycemic
metabolism and Drugs
326
maintenance of END1 Pha3 * *
blood sugar level Pharmacology 1
Insulin
Preparations
END1 Med3 1 * *
Clinical Faculty Overview

Of medicine /Diagnosis of
Diabetes
Describe the END1 Com2 1 * *

epidemiology of
diabetes mellitus in Community Epidemiology of
terms of global Medicine diabetes in
perspectives in Pakistan,preventio
Pakistan n and control at
primary care level
Describe the levels END1 Com3 1 * *
of prevention of
diabetes mellitus Community Obesity
and its control at Medicine
primary care level
Describe the 1 * *
development,
biochemical END1Ang6
structure,
Microscopic
secretions, mode of
structure of
action, functions,
adrenal gland
anomalies and
common related 1.5 * *
disorders of adrenal
END1 Anh5
gland
Microscopic
Anatomy
structure of adrenal
gland
327
1.5 * *
END1Ane4
Gross structure &

development of
adrenal gland
+anomalies of
development
END1 Phy11 * *
(Functions of gluco- 1
corticoids)
END1 Phy12 * *
Adrenal Cortex 1.5

(Functions of
mineralocorticoids)
Physiology
1 * *
END1 Phy13
Adrenal medulla
Secretions, MOA
and disorders
Pharmacology END1 Pha4 1
Steroids * *
328
Dow Medical College, DUHS
Endocrinology Module, Semester III , Week 1 Time Table
Days 8:30- 10:00 10:30- 11:30 11:30-12:30 1:30-3:00
Anatomy Lecture Physiology Biochemistry

Anatomical Introduction of Anatomy demonstration
Endocrinology, Classification of hormones
overview of all 5 batches
Control and based on chemical
1 endocrine glands in Gross, and development of
feedback structure and Mechanism
the body (Gross) Pituitary
of action
Name of faculty Name of faculty Name of faculty Venue
Venue
8:30-10:00am
Physiology: 1 10.00-11.00
Hypothalamus and Anatomy Lecture 11.0-12:00
Ant: Pituitary Microscopy of Anatomy demonstration
2 5 batches Gross structure
Hormones Pituitary
Name of faculty of hypothalamus
Venue Venue
PHYSIOLOGY
Biochemistry: PHYSIOLOGY:
2
Molecular structure Hormones of the posterior
Growth
and biochemical pituitary and related
hormone
functions of disorders (Function of SELF STUDY
3 Synthesis,
Anterior Pituitary Posterior Pituitary
function &
Hormones Hormones & diabetes
related disorders
Name of faculty insipid us
Name of
faculty Venue
329
Days 8.30-10:00 10.30-11.30 11.30-12.30 1.30-3.00

1-Histology Practical:
Microscopic structure of Pituitary
Gp.A
2- Physiology Tutorial: Disorders
Pathology COMMUNITY
Clinical Faculty of Ant. Pituitary Gp. B
Anterior pituitary MEDICINE
posterior pituitary Obesity Clinical Disorders of Pituitary Name of faculty Venue
1
Name of faculty Name of faculty Name of faculty Venue
3- CBL Gp.C
Venue Venue
4- SELF STUDY Gp.D
5.Skill LabGp.E1 (Examination of
prostate) self study Gp.E2
Anatomy Anatomy
Demonstration Development of 1.B
Gross structure of Thyroid and Physiology 2.C
thyroid and parathyroid and Function of Thyroid Hormones
2 3.D
parathyroid related anomalies Name of faculty Venue
4.E
Name of faculty Name of faculty
Venue Venue 5.A
Biochemistry Anatomy:
1.C
Thyroid: Synthesis Microscopic Pathology 2.D
mode of action, structure of Hypothyroidism
3 3.E
metabolic functions thyroid and Name of faculty Venue 4.A
Name of faculty parathyroid
5.B
Venue Name of faculty
Pathology Venue
Pharmacology
Physiology 1.D
hyperthyroidism and Drugs used in hypo
Function of Parathyroid 2.E
&
4 graves disease Hormones 3.A
Hyperthyroidism
Name of faculty DR. NADEEM Name of faculty Venue 4.B
Venue NLH-2 5.C
8:30-10:00am
Biochemistry:
10:30-12:00pm
Parathyroid hormone,
Pathology
5 Calcitonin and related
Disorders of parathyroid gland
disorders
Name of faculty
Venue
Clinical Faculty
Presentations of Pharmacology 1. E
Hypothyroidism / 2. A
Hyperthyroidism and SELF STUDY Drugs used in hypo and
6 3.B
Interpretation of hypercalcemia
4.C
laboratory Tests Name of faculty Venue 5. D
Name of faculty
Venue
330
Days
8:30- 10:00 10:30- 11:30 11:30-12:30 1:30-3:00
1 - GP-A - Histology Practical :

Microscopic structure of thyroid
parathyroid Name of faculty Venue
Anatomy 2 - GP-B - Physiology tutorial :

Thyroid function Test & BMR
Community Medicine:
Anatomy Demonstration: 5 Development of Name of faculty Venue )
batches pancreas and related
1 Gross structure of pancreas Iodine Control Program anomalies
Name of faculty 3-GP-C2 SKILL LAB GP-C1
Name of faculty Venue SELF STUDY
Venue
Name of faculty
4-GP-D. Biochemistry Practical: T3,
Venue
T4, TSH iodine levels, Long acting
thyroid Stimulator (Lab investigation
for thyroid functions)
5 - GP-E - CBL
Biochemistry:
Endocrine secretions
Physiology 1.B
Anatomy : of Pancreas, molecular
Hormonal secretion of 2.C
Microscopic structure of structure and
2 Pancreas (insulin) 3.D
pancreas biochemical function (
Name of faculty insulin) 4.E
Name of faculty Venue 5.A
Venue
Biochemistry:
Endocrine secretions of
Physiology Pharmacology 1.C
Pancreas, molecular
Hormonal secretion of Oral 2.D
structure and biochemical
3 Pancreas Glucagon, Hypoglycemic Drugs 3.E
function
somatostatin)
(Glucagon,somatostatin) Name of faculty 4.A
Name of faculty Venue Name of faculty Venue 5.B
Venue
Biochemistry: Community
Regulation of blood glucose Medicine:
level, hyper and Pathology 1 Epidemiology of 1.D
hypoglycemia. Complications Diabetes Pathogenesis diabetes in Pakistan, 2.E
4 Prevention &Control 3.A
of Diabetes Mellitus Name of faculty
e.g. Diabetic Keto-acidosis at primary care leve 4.B
Venue 5.C
and nonketotic complications. Name of faculty
8:30-9:30AM 9:30-10:30AM 10:30-12:00
Pathology Clinical Faculty 1.E
Diabetes Overview /Diagnosis 2.A
5 Complication of Diabetes 3.B
Name of faculty Name of faculty 4.C
Venue Venue 5.D
331
Day 8:30- 10:00 10:30- 11:30 11:30-12:30 1:30-3:00

s
1.A= Histology Practical: Microscopic
structure of pancreas & adrenal gland Name
of faculty Venue
2.B=Biochemistry Tutorial: Given a set of
Anatomy laboratory data, differentiate between hypo and
Anatomy (5-Batches)
Gross structure and Microscopic Pharmacology hyper secretion of Adrenal cortex Name of
development of adrenal structure of adrenal Insulin Preparations faculty Venue
1 gland +anomalies of gland Name of faculty 3. C=Biochemistry Tutorial: Biochemical
development Name of faculty interpretation for the diagnosis of Diabetes
Venue
Name of faculty Venue Venue mellitus Name of faculty Venue
4.D=CBL
5.E=Physiology: Pineal gland + local hormones
prostaglandins Name of faculty Venue
Biochemistry: 1. B
Biochemistry: Physiology Adrenocortical
Adrenocortical hormones hormones: Metabolic
2.C
(Functions of gluco-
synthesis & chemistry corticoids Function of 3.D
2
Name of faculty Name of faculty Glucocorticoids effect of 4.E
Venue Venue Synthetic Cortisone 5A
Name of faculty
Biochemistry: Venue
Physiology
adrenocortical Physiology 1.C
Adrenal Cortex hormones: Adrenal medulla 2.D
3 (Functions of electrolyte balance Secretions, and 3.E
mineralocorticoids) function of disorders 4.A
Name of faculty Venue mineralocorticoid Name of faculty Venue 5B
Name of faculty
Venue
Pathology Biochemistry:
Chemistry of 1 D.
adrenal medullary Pharmacology
Hypo and Hyper of Steroids
2.E
4 and associated 3.A
secretion of adrenal hormones with Name of faculty
Cortex &MEDULA Pheochromocytoma Venue 4.B
Name of faculty Name of faculty 5.C
Venue Venue
8:30-9:30AM 10:30-12:00
Clinical Faculty: DDRL
Testing of Endocrine 1.E
Medicine
5 Interpretation & functions 2.A
(Ketosteroids basal 3.B
Diagnosis of Hyper and levels in Blood,
Hypo Secretionof Urine, Saliva, etc 4.C
adrenal gland Name of faculty 5.D
6 Venue SELF STUDY
7 MODULE TEST
332
LEARNING OBJECTIVES
objectives:
ANATOMY
END1Ang 1 GROSS AND DEVELOPMENT OF PITUITARY AND RELATED ANOMALIES
Discuss the gross anatomy of pituitary gland.

Describe the development of pituitary gland.
Enumerate the congenital anomalies related to pituitary gland.
END1Ang 2 GROSS STRUCTURE OF THYROID AND PARATHYROID GLAND.
Recognize the anatomy of thyroid gland.

Define the relations of lobes of thyroid and isthmus of thyroid.
Discuss Blood vessels of supplying thyroid.
Discuss Nerve supply of thyroid.
END1Ang 3 GROSS ANATOMY OF PANCREAS
Describe the location, peritoneal relations, and morphological and

secretory parts of Pancreas
Describe the gross features of different parts of pancreas
Describe the arterial supply, venous drainage and nerve supply of pancreas
END1An5 ADRENAL GLAND
Outline structure of suprarenal gland

Identify the different zones of adrenal cortex
List the hormones released by adrenal cortex and there functions.
Know the relations of right and left adrenal glands
333
END1Ang6 ADRENAL GLANDS, RELATION OF STRUCTURE WITH FUNCTION
Define adrenal medulla

Describe Anatomy and divisin of adrenal medulla
Enlist and discuss Hormones of adrenal cortex,
Enlist and discuss Hormones of adrenal medulla.
END1Ang7 GROSS STRUCTURE OF THYROID AND PARATHYROID GLAND.
Discuss the anatomy of thyroid gland.

Define the relations of lobes of thyroid and isthmus of thyroid.
Discuss Blood vessels of supplying thyroid.
Discuss Nerve supply of thyroid.
HISTOLOGY
END1 Anh 1 MICROSCOPIC STRUCTURE OF THYROID GLAND
Identify the normal microscopic features of thyroid gland

Discuss the parenchymal and lobular cells of thyroid cells
END1 Anh2 MICROSCOPIC STRUCTURE OF PANCREAS

Discuss the histological components of pancreas
Describe the capsule and stroma pancreas
Discuss the Parenchyma and Lobules (acini) of Pancreas
Discuss the Duct System of Pancreas
Describe the endocrine component of pancreas
Discuss the differences between Parotid gland and Pancreas
END1Anh3 MICROSCOPIC STRUCTUREOF ADRENAL GLAND
Indentify :
o Points of identification.
o Histological differences.
o Disorders of Adrenal Gland
334
END1 Anh4 MICROSCOPIC STRUCTURE OF PARATHYROID GLAND
Identify Microscopic structure of Parathyroid Gland

Describe Points of identification
Discuss Disorders of parathyroid gland
END1 Anh 5 MICROSCOPY OF PITUITARY GLAND.
Identify the histological features of pituitary gland.

Discuss the different subtypes of the pituitary gland lobes.
EMBRYOLOGY
END1 Ane 1 DEVELOPMENT OF ADRENAL GLAND AND RELATED ANOMALIES
Discuss the development of adrenal gland.

Eneumerate the developmental anomalies of adrenal gland.
END1 Ane 2 DEVELOPMENT OF THYROID & PARATHYROID GLANDS AND

RELATED ANOMALIES
Discuss Embryological development of thyroid and parathyroid glands

Eneumerate Related developmental anomalies
PHYSIOLOGY
END1 Phy 1 THE PINEAL GLAND

To discuss:
What is pineal gland,
The anatomy of pineal gland,
The physiological functions of pineal gland,
Control of melatonin secretion,
What are prostaglandins,
335
Effects of prostaglandins,
Therapeutic uses of prostaglandins.
END1 Phy 2 INTRODUCTION TO ENDOCRINOLOGY.

Discuss definition of endocrine system and the classification of the
various chemical messenger systems in the body.
Discuss the difference of autocrines and paracrines.
Describe Role and function of the endocrine glands and hormones secreted
by them.
END1 Phy 3 REGULATION OF HORMONAL SECRETION
To discuss :
What is hormone,
Types of hormones,
Physiology of hormones,
Hormones as a signal,
Control of hormone secretion.
END1 Phy 4 FUNCTIONS OF THYROID HORMONE
Describe the functional anatomy of the Thyroid Gland.

Discuss the steps of production of thyroid hormones.
Tell the Effects of Thyroid hormones on BMR.
Describe the effect on metabolism of protein, carbohydrate and fat.
END1 Phy 5 FUNCTION OF PARATHYROID HORMONES
To discuss :
Parathyroid hormone location,histology,
Calcium & Phosphate Metabolism
Distribution & Balance of Ca & PO4
Diseases associated with the Parathyroid Gland
336
END1 Phy 6 HORMONES OF POSTERIOR PITUITARY AND RELATED DISORDERS
To discuss :
Overview of the posterior pituitary
The function of Oxytocin and ADH
Disorders of ADH
Clinical correlate
END1 Phy 8 FUNCTION OF PARATHYROID HORMONES
To discuss
Parathyroid hormone
Parathyroid hormone is the most important endocrine regulator of calcium
and phosphorus concentration in extra cellular fluid.
END1 Phy 9 FUNCTIONS OF THYROID HORMONE

Describe the functional anatomy of the Thyroid Gland.
Describe the steps of production of thyroid hormones.
Discuss the Effects of Thyroid hormones on BMR.
Describe the effect on metabolism of protein, carbohydrate and fat.
END1 Phy 10 ADRENAL CORTEX - FUNCTIONS OF THE GLUCOCORTICOIDS.
To discuss
Overview of the hormones of Adrenal Cortex.
Functions of Cortisol and actions on :
Carbohydrate metabolism.
Protein metabolism.
Fat metabolism
Anti-inflammatory action.
Immunity and blood cells
In stress
Allergic responses.
337
END1 Phy 11 THYROID SYNTHESIS, MODE OF ACTION, METABOLIC FUNCTIONS AND
DISORDERS
To discuss
The steps involved in Thyroid Hormone Synthesis

The chemical nature of Thyroid Hormones
Thyroid Hormone Transport and Protein Binding
The mode of action of Thyroid Hormones
The metabolic effects of Thyroid Hormones
Clinical Disorders of Thyroid Function
END1 Phy 12 HORMONAL SECRETION OF PANCREAS
Define and describe Endocrine and exocrine portion of pancreas.

Discuss the normal Insulin secretion.
Eneumerate different disorders of pancrease
BIOCHEMISTRY
END1 Bio1 Classification of hormones according to the chemical nature
Discuss the basic functions of endocrine system

Classify the hormones chemically
Recall the mechanism of action according to the chemical nature
Recognize the chemical properties and structure of each group of
hormones
END1 Bio 2THYROID SYNTHESIS, MODE OF ACTION, METABOLIC FUNCTIONS AND

DISORDERS
To discuss :
The steps involved in Thyroid Hormone Synthesis
The chemical nature of Thyroid Hormones
Thyroid Hormone Transport and Protein Binding
The mode of action of Thyroid Hormones
The metabolic effects of Thyroid Hormones
338
Clinical Disorders of Thyroid Function
END1 Bio3 ENDOCRINE

SECRETIONS OF PANCREAS-MOLECULAR STRUCTURE AND
BIOCHEMICAL FUNCTION (INSULIN)
To discuss:
Molecular structure of Insulin
Biosynthesis of Insulin
Mechanism of action of Insulin
Functions of Insulin
END1 Bio 4 Regulation of Blood Glucose Levels Hypoglycemia and Hyperglycemia
Define normal blood glucose level

Describe its regulation
Define Hypoglycemia
Enlist different causes of hypoglycemia
Define Hyperglycemia
Enlist different causes of hypoglycemia
Justify that hypoglycemia is more dangerous for life as compare to
hyperglycemia
END1 Bio5 METABOLIC SYNDROME
Definition of Metabolic Syndrome

discuss Visceral obesity is an indicator of the syndrome and an independent
marker for CVD
Describe Current and some potential future treatment options
END1 Bio6 Relate OBESITY, LEPTINS and Type II DIABETES
Define Diabetes mellitus

Define obesity
Describe Leptins
Describe the relation of diabetes with obesity
Justify the role of Leptins in obese diabetic conditions
339
END1 Bio7 ADRENAL CORTEX: FUNCTIONS OF MINERALOCORTICOIDS.
Define and discuss Mineralocorticoids

Describe the effects of high levels of Aldosterone on the kidney.
Give Aldosterone functions on Circulation.
Describe role Aldosterone show on muscles.
Give the factors that help in the regulation of Aldosterone.
END1 Bio8 ADRENOCORTICAL HORMONES CHEMISTRY AND SYNTHESIS
To Discuss:
The various adrenocortical hormones
The structure of these hormones
The important aspect of their synthesis
END1 Bio 9 METABOLIC FUNCTIONS OF MINERALOCORTICOIDS AND THEIR

DISORDERS
To Discuss
Mode of action
Functions
Diseases associated with deficiency and excess of mineralocorticoids
END1 Bio10 BIOCHEMISTRY OF ADRENAL MEDULLA & PHAEOCHOMOCYTOMA
Identify the parts of the adrenal gland

Identify hormones secreted by adrenal medulla and their main actions
Discuss the diseases caused by imbalance of adrenal medulla.
Discuss the common clinical presentation of phaeochromocytoma.
END1 Bio11 ADRENOCORTICAL

HORMONES CHEMISTRY, SYNTHESIS AND
METABOLIC FUNCTIONS OF GLUCOCORTICOIDS & DISORDERS
To understand :
The various adrenocortical hormones
340
The structure of these hormones
The important aspect of their synthesis.
The effects of Glucocorticoids on carbohydrate metabolism
The effects of Glucocorticoids on fat metabolism
The effects of Glucocorticoids on protein metabolism
The effects of Glucocorticoids on immune system
Glucocorticoids-As Anti-inflammatory Agents
PHARMACOLOGY
END1 Pha1 DRUGS USED IN HYPO AND HYPERCALCEMIA:
Understand the mechanism of action ,clinical uses and side effects of drugs
used in hypo and hyper calcemia
END1 Pha2 DRUGS USED IN HYPO AND HYPERTHYROIDISM
Understand the mechanism of action ,clinical uses and side effects of drugs
used in hypo and hyper thyroidism
END1 Pha 3 DRUGS USED IN HYPERGLYCEMIA
Enlist and understand the mechanism of action ,clinical uses and side
effects of drugs used in hyperglycemia
END1 Pha 4 DRUGS USED IN HYPERCORTISOLISM:
Enlist and understand the mechanism of action ,clinical uses and side
effects of Steroids
341
PATHOLOGY
END1 Pth 1 DISORDERS OF ANTERIOR PITUITARY.
Discuss overview of the pituitary gland.

Define the cell types present in the anterior pituitary.
Describe the function of hormones and how they are involved in regulating
pigmentation in humans.
Describe the basis of conditions where pituitary function and growth
hormone secretion and function are abnormal, and how they can be
treated.
END1 Pth 2 HYPERTHYROIDISM AND GRAVES DISEASE
Discuss pathophysiology of hyper thyroidism

Identify microscopic features of hyperthyroidism
END1 Pth 3 DISORDERS OF PARATHYROID
Discuss functions of Parathyroid Hormone.

Discuss the mode of action of PTH.
Emphasize on the role of calcium and phosphorus in the body.
Explain the types of Parathyroid Disorders.
Give their symptoms and causes.
END1 Pth4 DISORDERS OF HYPER AND HYPO CORTI
CLINICAL
END1 Med1 SIGNS & SYMPTOMS OF HYPO/HYPERTHYROIDISM
Discuss the normal regular functioning of thyroid gland.

Enlist the common investigations used for thyroid functional disorders
Describe clinical signs & symptoms caused by excess or deficiency of
thyroid hormone.
342
END1 Med2 CLINICAL DISORDERS OF ADRENAL GLAND
Discuss the common diseases caused by excess or deficiency of adrenal

hormones.
Describe the common clinical presentation of these disorders.
END1 Med3 CLINICAL DISORDERS OF PITUITARY
To identify the parts of the pituitary gland

To identify hormones secreted by each lobe and their main actions
Discuss the common diseases caused by excess or deficiency of pituitary
hormones
Recognize and discuss the common clinical presentation of these disorders
COMMUNITY MEDICINE
END1 COM 1 IODINE CONTROL PROGRAM IN PAKISTAN
Discuss the epidemiology and consequences of iodine deficiency and the

salient features of iodine control program in Pakistan
Prevalence and causes of Iodine deficiency in Pakistan
Iodine control program in Pakistan
Endocrinology Module:
I. Introduction to Examination Of Prostate
Introduction/Rationale:
Examination of prostate is an important skill for early diagnosis of cancer and other disease.
Demonstrate the correct technique of examination of prostate.
343
CASE BASED LEARNING
END1Cbl1
Identify the anatomical structures involved in these physical findings.

Describe the physiology of Growth Hormone secretion and regulation.
Correlate the physical findings of underlying hormonal disorder with
normal functions.
Interpret the investigations of relevant gland.
To prescribed the treatment and monitor the response of treatment.
END1Cbl2
Describe the secretion and regulation of insulin

Identify deficiency of insulin on basis of symptom
Describe the pathogenesis Diabetes Mellitus
Identify the anatomical structure involved.
END1Cbl3
Understanding pathophysiology of addisions disease

Able to diagnose hormonal problems on basis of clinical features
Able to identify anatomical structures involved
END1Cbl4
Discuss the structure and functions of thyroid gland

Recognize the mechanism of action of thyroid Hormones and regulation
Relate the clinical picture with the presentation of such clinical condition.
Recognize the importance of selection of salt utilized in cooking
Recognize the social issues related to swelling in front of neck
Identify the anatomical structures of the endocrine gland in front of the
neck
Discuss the synthesis of T3 T4
344
WEEKS/HOURS 1st 2nd 3rd 4th TOTAL *** ROUND OFF
PATHOLOGY - 5.5 2 1.5 9 11.32 11
ANATOMY 5 6.5 5.5 3 20 25.15 25
PHYSIOLOGY 4.5 3.5 4 5 17 20.38 20
SKILL LAB - 1.5 1.5 - 3 3.27 3
CLINICAL
- 2.5 1 1 4.5 5.34 5
FACULTY
BIOCHEMISTRY 2.5 3 5 7.5 18 22.34 22
PHARMACOLOGY - 2 1 2 5 6.28 6
COMMUNITY
- 1 1 - 2 2.515 2
MEDICINE
DDRL - - - 1 1 1.257 1
TOTAL T1 12 27 24.5 22.5 79.5 100 100
Total 2 CBL - 1.5 1.5 1.5 4.5 - 10
345
ENDOCRINOLOGY-1 MODULE
(SEMESTER-III)
SUMMATIVE ASSESMENT
THEORY

SEMESTER
ATP 25
EXAM
PAPER-III One best Questions

20
based on CBL
80%
Total 100
MODULE EXAM
EMQs 10
ATP 20
MODULE PAPER
20
based on CBL
Total 100
STRUCTURED VIVA

ASSESMENT
SUMMATIVE
SEMESTER
EXAM
See Semester
Assessment Plan
ASSESMENT TOOLS
Structured Feedback
Facilitator
NOTE: Paper I & IV-A of Semester-3 Examination are Based on Neurosciences Module.
Paper II & IV-B of Semester-3 Examination are Based on Head & Neck Module.
346
CREDIT HOURS
SEMESTER III
Paper-III 3
END-1
Paper-IV-C 1.5
347
PAPER CONTENT WEIGHTAGE CREDIT HOURS
Neurosciences Module
80 Marks
(Semester Theory)
100
I Marks 6
Neurosciecnes Module
20 Marks
(Module Exam)
Head & Neck Module

40 Marks
II Head & Neck Module
Marks 3
10 Marks
(Module Exam)
Endocrinology Module
40 Marks
(Semester Theory)
50
III Marks 3
10 Marks
(Module Exam)
Neurosciences Module
a
(Viva)
50 Marks 3
Head & Neck Module 100

IV b
(Viva)
25 Marks
Marks
1.5
C
(Viva)
25 Marks 1.5
348
349
SEMESTER -4
GI and Liver-1 Module 8 Weeks 9 Credit Hours
Reproduction-1 Module 4 Weeks 4.5 Credit Hours
Renal & Excretory System-1 Module 4 Weeks 4.5 Credit Hours
350
GASTROINTESTINAL TRACT & LIVER MODULE
CODE: GIL-1
SEMESTER IV
SECOND (2ND) YEAR M.B; B.S
351
Spiral Sem. Modules

II

4 Week
wks
Second th
Spiral th
Trauma, 6 week
3 week 8 Weeks
/ Burns 2 wk
2 Weeks
th
th
PARALLEL THEMES:
352
GIL MODULE COMMITTEE
Dr Talat Yasmeen, Professor of Anatomy, DUHS
Dr Naheed, Assistant Professor of Anatomy, DUHS
Dr Aijaz Qureshi, Associate Professor of Physiology, DUHS
Dr Rubeen, Associate Professor of Biochemistry, DUHS
DrS hamama, Associate Professor of Pharmacology, DUHS
Dr. Rubina Gulzar, Assistant Professor of Pathology, DUHS
Dr. Saba , Assistant Professor of Pathology, DUHS
Dr. Aisha Mehnaz, Professor of Pediatrics. DUHS
Dr. Rauf Memon, Associate Professor of Medicine, DUHS
Dr Sajida Qureshi, Assistant Professor of Surgery, DUHS
Capt. Dr. Farhat Mirza, Professor of Forensic Medicine, DUHS (Forensic Medicine)
Dr. Nighat Nisar, Professor of Community Medicine, DUHS (Community Medicine)
Dr. Raza-ur-Rehman, Professor of Psychiatry, DUHS (Behavioral Sciences)



Module committee
Curriculum
353
RATIONALE
Gastrointestinal tract and liver play a vital role in the life of a human beings .The
processes of ingestion, digestion, absorption, assimilation and metabolism of the food
for its ultimate utilization as a source of energy and biostructural molecules are
performed in these organs. Liver is the organ where major metabolic functions take
place. It is important for undergraduate students of medicine to have basic knowledge
about the functions & diseases of gastrointestinal tract and liver and their management
and for that a sound understanding of the structure, function, biochemical processes
and their relationship to the disease processes is essential. All of these are taught in this
module in an integrated fashion.
TERMINAL OBJECTIVE
At the end of this module student will be able to:
Review anatomy of gastro-intestinal tract.

Describe embryological development
Highlight common developmental anomalies of gastro-intestinal tract.
Enlist various enzymes and describe their composition and synthesis.
Explain gastrointestinal tract on the basis of its physiology.
Identify common pathologies in relation to digestion, absorption and
storage.
Recognize importance of liver in the process of digestion, absorption and
storage.
Explain pathological findings of hepatic diseases.
Interpret common investigations done to diagnose gastro-intestinal tract
related pathologies.
354
methodology
BCQS, SEQS EMQS

DIGITAL LIBRARY
SELF STUDY
TUTORIALS
PRACTICAL
PRACTICAL
LECTURES
SKILL LAB
LIBRARY
VIVA
CBL
LEARNING OBJECTIVES FACULTY TOPIC/CONTENT
Assessment
GIL1 Ang 1:Introduction 1 * *

1. Identify the & divisions of GIT +
boundaries and abdominal quadrants
divisions ANATOMY GIL1 Ang 2: Division of 1.5 * *
Gastrointestinal tract abdomen into regions
and quadrants and their
contents
GIL1 Ang 3: surface 1.5 * *
anatomy of abdomen
GIL1 Ang 4: Anterior 1.5 * * *

abdominal wall
PHYSIOLOGY GIL1 Phy1: Introduction 1 * *

to the digestive system
SKILL LAB GIL1 Skl 1: Introduction 1.5 * * *

to abdominal
examination
GIL1 Phy 2: Functions of 1 * * *

2. Describe the the smooth muscle and
Structure of smooth their electrical properties
muscle and their GIL1 Phy 3: Ingestion of 1.5 * * *
electrical properties, to food (mastication reflex)
recognize the major PHYSIOLOGY
organs of the digestive
system and cross- GIL1 Phy 4: Nervous and 1 * *
section of wall of the hormonal control of GIT
digestive tract. The
nervous and hormonal
355
control of GIT and ANATOMY GIL1 Ang 5: Nerves of 1.5 * * *
ingestion of food. abdomen
ANATOMY GIL1 Ang 6: Inguinal Canal 1.5 * * *

3. Identify the
abdominal regions in
RADIOLOGY GIL1 Rad 1: Assessment 1 * * *
location of different
of GIT(PLAIN X RAY & BA
viscera in abdominal STUDIES)
regions and planes RADIOLOGY GIL1 Rad 2: Assessment 1 * * *

of GIT(ULTRASOUND)
GIL1 Rad 3: Assessment 1 * * *

of GIT(CT SCAN)
SURGERY GIL1 Sur 1: Hernia 1 * * *
CBL GIL1 Cbl1: CBL 1.5 * *
GIL1 Ang 7: Overview of 1.5 * *

4. Recognize the details ANATOMY peritoneal Cavity &
of peritoneum and peritoneal reflections +
peritoneal reflections vertical disposition
on the different GIL1 Ang 8: Peritoneum 1.5 * * *
contents of abdominal horizontal disposition
& peritoneal cavity.
SKILL LAB GIL1 Skl 2: Gut Sounds 1.5 * * *
ANATOMY GIL1 Ang 9: Lumbar 1.5 * *

5.Identify the Vertebrae
structures forming the
posterior abdominal
wall and viscera related GIL1 Ang 10: Posterior 1.5 * *
to them abdominal wall
(boundaries, Muscles,
fascia)
GIL1 Ang 11: Lymphatic 1.5 * *
drainage of Abdomen
EMBRYOLOGY GIL1 Ane 1: Development 1 * *

of GIT
6. Describe the (derivatives of fore gut)
location, development, ANATOMY GIL1 Ang 12: Esophagus 1 * *
gross anatomy, (Abdominal Part),
microscopic anatomy Stomach
356
and clinical anatomy of ANATOMY GIL1 Ang 13: Duodenum 1 * *
different viscera and pancreas
present in abdominal
cavity EMBRYOLOGY GIL1 Ane 2: Development 1 * *
Anatomy of GIT (2)
(derivatives of mid and
hind gut)
GIL1 Ane 3: Congenital 1 * *

Anomalies of GIT(I)
GIL1 Ane 4: Congenital 1 * *

Anomalies of GIT(II)
HISTOLOGY GIL1 Anh 1: General plan 1 * *

of G.I.T + Oesophagus
GIL1 Anh 2: Stomach 1 * *
GIL1 Anh 3: Esophagus 1 * *

+stomach
GIL1 Anh 4: Pancreas, 1 * *

Duodenum
GIL1 Anh 5: Small 1 * *

intestine
GIL1 Anh 6: Pancreas 1 * *
GIL1 Anh 7: small & large 1 * * *

Intestine
CBL GIL1 Cbl 2: CBL 1.5 * *
ANATOMY GIL1 Ang 20: anal canal
ANATOMY GIL1 Ang 14: Small 1.5 * * *

7.Identify the Intestine & large
components of large intestine+ (comparison of
intestine, and emphasis two)
the importance of HISTOLOGY GIL1 Anh 8: Large 1 * *
rectum and anal canal intestine
for normal functioning
of the body. PATHOLOGY GIL1 Pth 1: 1 * * *
Malabsorption and celiac
disease
GIL1 Pth 2: Inflammatory 1 * * *
bowel disease
357
ANATOMY GIL1 Ang 15: Abdominal 1 * * *
8.Describe the major Aorta + blood supply of
vessels of GIT and Liver abdomen
GIL1 Ang 16: inferior vena 1 * * *
cava+ venous drainage of
abdomen
PATHOLOGY GIL1 Pth 3: Circulatory 1 * * *
disorders of liver
ANATOMY GIL1 Ang 17: Liver 1 * *

9.Describe the details
of hepato-biliary
GIL1 Ang 18: Gall bladder 1 * *
system(Extra-hepatic
and biliary tract
and intra hepatic)
GIL1 Ang 19: Hepatic 1 * *
portal system
HISTOLOGY GIL1 Anh 9: Histology of 1.5 * *
Liver and gall bladder
GIL1 Anh 10: Histology of 1 * *
gall bladder
GIL1 Anh 11: Histology of 1 * *
liver
EMBRYOLOGY GIL1 Ane 5: Development 1 * *
of liver, Gall bladder and
pancreas
BIOCHEMISTRY GIL1 Bio 1: Use of 1.5 * * *

10.Describe role of liver colorimetry for diagnosis
in the metabolism of of diseases
carbohydrates, lipids GIL1 Bio 2: Interpret the 1.5 * * *
and proteins estimations of bilirubin
GIL1 Bio 3: Overview of 1 * *
exocrine functions of
Liver and Pancreas
related to micro and
macronutrients
MEDICINE GIL1 Med 1: Liver 1 * * *
function tests
MICROBIOLOGY GIL1 Mic 1: Hepatotropic 1 * *
viruses
BIOCHEMISTRY GIL1 Bio 4: Interpret the 1.5 * * *
estimations of Alkaline
Phosphatase and
aminotransferases
GIL1 Bio 5: jaundice 1 * * *
PATHOLOGY GIL1 Pth 4: Acute 1 * *

hepatitis
GIL1 Pth 5: Chronic 1 * *

hepatitis & Cirrhosis
358
11.Explain the process BIOCHEMISTRY GIL1 Bio 6: Role of 1 * *

of synthesis and glycogen in well fed,
degradation of fasting, starvation and
glycogen malnutrition states
(Glycogenesis&Glycogeno
lysis)
12.Relate metabolism BIOCHEMISTRY GIL1 Bio 7: Glycogen 1 * *

of glycogen with Storage diseases
malnutrition and
storage disease
13.Explain the process BIOCHEMISTRY GIL1 Bio 8: Over view of 1 * *
of digestion of dietary Digestion and Absorption
carbohydrate, lipid & of carbohydrates, lipids
protein and proteins
GIL1 Bio 9: Overview of 1 * *

nitrogen metabolism
(digestion& transport of
amino acid into cell,
removal of nitrogen from
amino acids)
13.Describe the BIOCHEMISTRY GIL1 Bio 10: Degradation 1 * *

biochemical structure of dietary Lipids and their
and function of transport
lipoproteins
14.Relate the normal BIOCHEMISTRY GIL1 Bio 11: 1 * *
process of digestion & Malabsorption syndrome
absorption of (biochemical background)
carbohydrates, lipids &
proteins with
absorption syndromes
15.Explain the process BIOCHEMISTRY GIL1 Bio 12: 1 * *

of oxidation of glucose Gluconeogenesis
GIL1 Bio 13: Human Body 1.5 * * *

general needs & levels for
glucose and its regulation
(Glycolysis, insulin,
glucagon)
GIL1 Bio 14: Interpret the 1.5 * * *
estimations of Glucose by
spectrophotometry and
glucometer
16.Justify the BIOCHEMISTRY GIL1 Bio 15: HMP shunt 1 * *
significance of HMP
with respect to
359
reducing equivalents &
other sugars
17.Describe the BIOCHEMISTRY GIL1 Bio 16: Metabolism 1 * *
synthesis of glucose of bilirubin & Bile salt
from non-carbohydrate synthesis
sources (Uronic Acid path & role
of glucuronate)
18.Relate the glucose BIOCHEMISTRY GIL1 Bio 17: Common 1 * *
oxidation with energy Metabolic pathway for
production through energy Provision from
TCA, cycle electron CHO, lipids and Amino
transport chain & acid (TCA Cycle/ Krebs
oxidative Cycle)
phosphorylation GIL1 Bio 18: Body Energy 1 * *
Gradient Maintenance
(Electron Transport Chain
& Oxidative
Phosphorylation)
19.Describe the process BIOCHEMISTRY GIL1 Bio 19: Amino acid 1 * *

of ammonia transport degradation and
and formation of urea synthesis. Urea cycle and
metabolism of ammonia
20.Relate BIOCHEMISTRY GIL1 Bio 20: 1 * *

carbohydrate, protein Carbohydrate, Lipids &
& lipid metabolic Proteins Metabolism In
processes in well-fed Well fed state and
states, obesity, Obesity
starvation and diabetes
mellitus GIL1 Bio 21: 1 * *
Carbohydrate, Lipids &
Proteins Metabolism in
Starvation and Diabetes
mellitus
BIOCHEMISTRY GIL1 Bio 22: Composition 1.5 * * *

21.Discuss the fate of of Peritoneal fluid in
amino acids after relation to Peritoneal
absorption Dialysis
GIL1 Bio 23: Phenyl 1 * *

Alanine, Tyrosine,
Tryptophan, Methionine.
Branch chain amino acids,
Glycine, Histidine,
Creatine&creatinine
GIL1 Bio 24: Metabolic 1 * *
defects in amino acid
metabolism
22. Relate the BIOCHEMISTRY GIL1 Bio 25: Coenzymes 1 * *
role of water soluble derived from vitamins
vitamins in metabolism and their role in
as coenzymes metabolic actions
360
Explain how MEDICINE GIL1 Med 2: Fatty liver 1 * *

hyperammonemia disease
results from chronic BIOCHEMISTRY GIL1 Bio 26: Fatty Acids 1 * * *
liver disease and Ketone bodys
metabolism in human
body
23.Discuss fatty acid BIOCHEMISTRY GIL1 Bio 27: Fate of 1 * *
synthesis its oxidation, Dietary Cholesterol and
ketogenesis and indigenous Cholesterol in
cholesterol synthesis human body (Metabolism
of Cholesterol)
estimations of
cholesterol
estimations of Tri-acyl-
glycerole and
Estimations of total lipid
24. Describe the PHARMACOLOGY GIL1 Pha 1: Anti-diarrheal 1 * * *

differences in the drugs
nature of GIL1 Pha 2: laxative 1 * * *
gastrointestinal motility
as a function of
position and time. GIL1 Pha 3: Antiemetic/ 1 * * *
pro-kinetic agents
PHYSIOLOGY GIL1 Phy 5: Motor 1 * *
functions of esophagus
&stomach
GIL1 Phy 7: Movements 1 * *
of small intestine & large
intestine
PATHOLOGY GIL1 Pth 6: Motor 1 * *
disorders, varices,
esophagitis &Baretts
26. Recognize PATHOLOGY GIL1 Pth 7: Acute & 1 * *
Factors that control the chronic gastritis
rate of emptying of the
stomach and PHARMACOLOGY GIL1 Pha 4: Antisecretory 1 * * *
mechanism of the drugs: H2-antagonists
control
GIL1 Pha 5: Antisecretory: 1 * * *
PPI & miscellaneous
27. Discuss the PHYSIOLOGY GIL1 Phy 8: Secretions of 1 * * *

composition, saliva (composition,
mechanism of function and regulation)
secretion, functions, PATHOLOGY GIL1 Pth 8: Diseases of 1 * *
nervous and hormonal salivary gland (non-
regulation of gastro- tumors & tumors)
361
intestinal juices. And PHYSIOLOGY GIL1 Phy 9: Gastric 1 * *
juices of accessory secretion (composition,
organs such as salivary function and regulation)
gland, pancreas and GIL1 Phy 10: Secretions of 1 * *
liver. small and large intestine
PATHOLOGY GIL1 Pth 9: Peptic ulcer 1 * *
and H. pylori association
MICROBIOLOGY GIL1 Mic 2: Diagnosis of 1 * * *
H. pylori infection in
clinical practice
PHYSIOLOGY GIL1 Phy 11: Bile 1 * *
secretion (composition,
function and regulation)
GIL1 Phy 12: Pancreatic 1 * * *
secretion (composition,
function and regulation)
PATHOLOGY GIL1 Pth 10: Pancreatitis 1 * *
COMMUNITY GIL1 Com 1: Study design 1 * *

COMMUNITY MEDICINE 1
GIL1 Com 2: Study design 1 * *
2
GIL1 Com 3: How to 1 * *
Conduct research
GIL1 Com 4: Dynamics of 1 * *
Diseases Transmission
BEHAVIOUR SCIENCES BEHAVIOURIAL GIL1 Beh1: Social support 1 * *
SCIENCES treatment stigma.
GIL1 Beh 2: Social 1 * *
structure role and child
rearing practices
GIL1 Beh 3: Family 1
GIL1 Beh 4: Health belief 1 * *

model and explanatory
Model
362
GIT AND LIVER
TIME TABLE
FIRST WEEK
Days 8.30-------10.00 10.30-------11.30 11.30--------12.30 1.30-----------3.00
ANATOMY ANATOMY DEMO:

ANATOMY PHYSIOLOGY
Introduction to the Development of GIT Anterior abdominal wall
Introduction & divisions of GIT + abdominal
1 digestive system (derivatives of fore gut) A+B= Name of faculty Venue
quadrants
Name of faculty Name of faculty C+D= Name of faculty Venue
Venue Venue E= Name of faculty Venue
A=Histology practical: Esophagus
+stomach
B=Physiology: Ingestion of food (mastication
reflex) Name of faculty Venue PHYSIOLOGY
Functions of the HISTOLOGY
C=Biochemistry: Use of colorimetry for
smooth muscle and General plan of G.I.T + ANATOMY DEMO
diagnosis of diseases (Relate with Kit
2 their electrical Oesophagus Inguinal Canal
methods
properties Name of faculty Name of faculty Venue
Name of faculty
D=Anatomy: divisionVenue
of abdomen into
regions and quadrants and their contents Name of faculty Venue
,anatomy museumName of faculty Venue
Venue
E1: Skill lab: Introduction to abdominal
examinationName of faculty Venue
E2: self study
PHYSIOLOGY BIOCHEMISTRY
1. B SELF STUDY
2. C Nervous and hormonal Over view of Digestion and
Peritoneum
3 3. D control of GIT Absorption of carbohydrates, lipids
Name of faculty and proteins
4. E Name of faculty
5. A Venue Name of faculty Venue
Venue
PHYSIOLOGY
Secretions of saliva PATHOLOGY ANATOMY DEMO:
1. C Diseases of salivary
2. D (composition, Overview of peritoneal Cavity
gland (non-tumors &
4 3. E function and tumors) &peritoneal reflections + vertical
4. A regulation) Name of faculty disposition
5. B Name of faculty Venue Name of faculty Venue
Venue
1. D (10:00 TO 12:00)
2. E ANATOMY DEMONSTRATION:
5 3. A Esophagus (Abdominal Part), Stomach
4. B Name of faculty Venue
5. C
1. E HISTOLOGY PHYSIOLOGY
Motor Functions Of PATHOLOGY
2. A STOMACH Motor disorders, varices, esophagitis
6 3. B Esophagus &Stomach
Name of faculty &Baretts
4. C Name of faculty Name of faculty Venue
5. D Venue
Venue
363
TIME TABLE SEMESTER IV
GIT AND LIVER TIME TABLE SECOND WEEKs
Days 08:30------10:00 10:30------11:30 11:30------12:30 1:30-------3:00
PHYSIOLOGY
Gastric secretion ANATOMY
GROSS ANATOMY SELF-STUDY
(BLOOD SUPPLY
(composition, Abdominal Aorta + blood supply of
1 Duodenum and pancreas
OF GIT). function and abdomen
Name of faculty Venue regulation) Name of faculty Venue
Name of
faculty Venue
1- GP. A :Histology practical:
Pancreas, Duodenum
2- GP. B: SELF STUDY PATHOLOGY
Acute & chronic ANATOMY DEMO:
PHARMACOLOG
3-GP. C: Biochemistry: (5 Batches )
gastritis Y
2 Composition of Peritoneal fluid in Antacids Peritoneum
Name of horizontal disposition
relation to Peritoneal Dialysis
Name of faculty Venue faculty
Name of Name of faculty Venue
Venue
4-GP. D: CBL faculty Venue
5-GP. E1: Self-study
E2: SKILL LAB: Introduction to
abdominal examination
ANATOMY
Development
Anatomy of GIT
1. B HISTOLOGY
(2) (derivatives BIOCHEMISTRY
2. C Small intestine
of mid and hind Coenzymes derived from vitamins and
3 3. D
4. E gut) Name of their role in metabolic actions (Vit:
5. A Name of B3,4,5,6.)
faculty Venue
faculty
Venue
1. C HISTOLOGY PHYSIOLOGY GROSS ANATOMY
Large intestine Secretions of small
2. D Small Intestine & large intestine
4 3. E
Name of and large intestine
+(comparison of two)
4. A faculty Name of
5. B Venue faculty Venue Name of faculty Venue
PHYSIOLOGY PHARMACOLOGY
1. D Movements of Antisecretory
2. E small intestine & drugs: H2-
5 3. A large intestine
antagonists
4. B Name of
5. C
Name of
faculty
Venue faculty Venue
1. E
MICROBIOLOGY
2. A PATHOLOGY
Diagnosis of H. pylori infection in clinical
6 3. B Peptic ulcer and H. pylori association
practice
4. C Name of faculty Venue
5. D
364
GIT AND LIVER TIME TABLE THIRD WEEK
Days 08:30------10:00 10:30------11:30 11:30------12:30 1:30-------3:00
ANATOMY PHYSIOLOGY
PHARMACOLOGY HISTOLOGY Pancreatic secretion PATHOLOGY
1 Antisecretory: PPI & miscellaneous Pancreas (composition, function Pancreatitis
Name of faculty and regulation)
Venue
1.A-Histology practical
small & large Intestine Name of
faculty Venue
2.B- SELF-STUDY BIOCHEMISTRY
3.C- Biochemistry Pract: Interpret Mal absorption PATHOLOGY
the estimations of bilirubin Syndromes Malabsorption and Gross Anatomy:
Name of faculty Venue celiac disease Liver
2 (Biochemical
4.-D-CBL
background) Name of faculty Name of faculty Venue
5.E- BIOCHEMISTRYHuman Name of faculty Venue
Body general needs & levels for Venue
glucose and its regulation
(Glycolysis, insulin, glucagon)
tutorial Name of faculty Venue
1. B PATHOLOGY
2. C Inflammatory bowel PHARMACOLOGY Gross Anatomy:
3 3. D disease Anti-diarrheal Hepatic portal system
4. E Name of faculty Name of faculty Name of faculty Venue
5. A Venue Venue
1. C
2. D GROSS ANATOMY- 12-00 TO
Gall bladder and biliary tract SELF STUDY
4 3. E 12:30
4. A Name of faculty Venue SELF STUDY
5. B
1. D BIOCHEMISTRY
2. E
Overview of exocrine functions of Liver and
5 3. A
Pancreas related to micro and macronutrients
4. B
5. C Name of faculty Venue
1. E COMMUNITY
Histology
2. A MEDICINE
Histology of Liver and
dynamics of disease
6 3. B gall bladder SELF STUDY
transmission
4. C Name of faculty
Name of faculty
5. D Venue
Venue
365
GIT AND LIVER TIME TABLE FOURTH WEEK
Days 08:30------10:00 10:30------11:30 11:30------12:30 1:30-------3:00
1.C-Histology practical
small & large Intestine Name of
Biochemistry
faculty Venue Physiology Metabolism of bilirubin &Bile
2.D- SELF-STUDY Anatomy Bile secretion salt synthesis
3.E- SELF-STUDY Development of liver, Gall bladder (composition, function (Uronic Acid pathway & role
1 4.-A-CBL HALL 101 and regulation)
and pancreas of glucuronate)
5.B- BIOCHEMISTRY Human Body
general needs & levels for glucose and its Venue Name of faculty
regulation (Glycolysis, insulin, glucagon) Venue
tutorial Name of faculty Venue
1-A-Biochemistry Practical:
Interpret the estimations of Glucose by
spectrophotometery and glucometer
2. B2: SKILL LAB=Gut Sounds BIOCHEMISTRY
Common Metabolic pathway
B1- Self-study Name of faculty ANATOMY for energy Provision from
Venue PATHOLOGY Congenital Anomalies of CHO, lipids and Amino acids
Acute hepatitis GIT(I)
2 3-C-CBL (TCA Cycle/ Krebs Cycle)
Name of faculty Venue Name of faculty Name of faculty
4-D-Histology Practical
Venue Venue
Histology of Liver and gall bladder Name
of faculty Venue
5.E= Biochemistry Pract: Interpret the
estimations of bilirubin
Name of faculty Venue.
BIOCHEMISTRY PATHOLOGY Biochemistry
Role of glycogen in well fed, Chronic hepatitis Body Energy Gradient
1. B
fasting, starvation and malnutrition & Maintenance
2. C
states Cirrhosis
3 3. D (Electron Transport Chain &
4. E (Glycogenesis&Glycogeno-lysis) Name of faculty Oxidative Phosphorylation)
5. A Name of faculty Venue Venue Name of faculty
Venue
1. C
B.S. GROSS ANATOMY:
BIOCHEMISTRY
Social support Spleen
2. D
Gluconeogenesis treatment stigma. Name of faculty
4 3. E
4. A Name of faculty Venue Name of faculty Venue
5. B Venue
1. D BIOCHEMISTRY
2. E Hexose Mono Phosphate Shunt
5 3. A ( Metabolism of sucrose & fructose, Galactose Metabolism &
4. B lactose Synthesis)
5. C= SELF STUDY
1. E
BIOCHEMISTRY MICROBIOLOGY
2. A Hepatotropic viruses
6 3. B JaundiceName of faculty SELF STUDY
Name of faculty
4. C Venue Venue
5. D= SELF STUDY
366
TIME TABLE SEMESTER V
GIT AND LIVER TIME TABLE FIFTH WEEK
Days 08:30------10:00 10:30------11:30 11:30------12:30 1:30-------3:00
COMMUNITY
6. D BIOCHEMISTRY MEDICINE GROSS ANATOMY: 5
7. E how to conduct BATCHES
Glycogen storage disease
1 8. A Lumbar Vertebrae
Name of faculty research
9. B
C= SELF STUDY
Venue
Venue
1-A-Biochemistry Practical:
Interpret the estimations of Alkaline
Phosphatase & aminotransferase
Name of faculty Venue BIOCHEMISTRY
2.B1-Skill lab: Gut sounds ANATOMY
ANATOMY 5 BATCHES
B2- SELF-STUDY Fatty Acids and Ketone Congenital Anomalies Posterior abdominal wall
2 bodys metabolism in of GIT (II) (boundaries, Muscles, fascia)
3-C-CBL
human body Name of faculty Name of faculty Venue
4-D- A-Biochemistry Practical: Name of faculty Venue
Interpret the estimations of cholesterol Venue
5.E-Self study
BIOCHEMISTRY
1. B BIOCHEMISTRY Degradation of dietary Lipids
2. C Fate of Dietary Cholesterol and indigenous Cholesterol
in human body and their transport
3 3. D
4. E (Metabolism of Cholesterol) (Lipoproteins)
5. A Name of faculty Venue Name of faculty Venue
RADIOLOGY- 1 PATHOLOGY
1. C Assessment of
2. D Circulatory disorders of ANATOMY
GIT(PLAIN X RAY &
4 3. E liver inferior vena cava+ venous drainage
BA STUDIES)
4. A Name of faculty of abdomen
Name of faculty
5. B Venue Venue Name of faculty Venue
1. D
2. E 10.30-12.00
5 3. A Anatomy : Nerves of abdomen
4. B Name of faculty Venue
5. C
1. E BIOCHEMISTRY
2. A Overview of nitrogen metabolism
6 3. B (digestion& transport of amino acid into cell, removal SELF STUDY
4. C of nitrogen from amino acids)
5. D Name of faculty Venue
367
GIT AND LIVER TIME TABLE SIXTH WEEK
Days 08:30------10:00 10:30------11:30 11:30------12:30 1:30-------3:00
6. E BIOCHEMISTRY
7. A Overview of nitrogen metabolism COMMUNITY MEDICINE
1 8. B (digestion& transport of amino acid into cell, removal of study design 1
9. C nitrogen from amino acids)
10. D Name of faculty Venue Name of faculty Venue
1: A+B-Biochemistry tutorial:
hyperammonia
BIOCHEMISTRY PHARMACOLOGY
2-C+ D-Biochemistry Practical:
Amino acid degradation and synthesis, Antiemetic/ pro-kinetic agents
2 Interpret the estimations of Tri-acyl-
Urea cycle and metabolism of ammonia
glycerol and Estimations of total Name of faculty Venue
lipidName of faculty Venue
3. E= Histology: RECTUM
BIOCHEMISTRY:
1. C+D Phenyl Alanine, Tyrosine, Tryptophan, Methionine
Branch chain amino acids, Glycine, Histidine, SELF STUDY
3 2. E
3. A+B Creatine&creatinine
BEHAVIOR
PHARMACOLOGY SCIENCES COMMUNITY MEDICINE
1. E Laxative study design 2
Family
4 2. A+B Name of faculty
3. C+D Name of faculty Name of faculty Venue
Venue
Venue
BIOCHEMISTRY ANATOMY
Metabolic defects in amino acid Rectum
5 metabolism
BEHAVIOR SCIENCES
Social structure role and child BIOCHEMISTRY
rearing practices Carbohydrate, Lipids & Proteins Metabolism
6 In Well fed state and Obesity SELF STUDY
368
GIT AND LIVER TIME TABLE SEVENTH WEEK
11:30 --
Days 08-:30 ---- 10:00
10:30 ----- 11:30 -- 1:30 ----- 03:00
12:30
BEHAVIOR SCIENCES BIOCHEMISTRY GROSS ANATOMY: 5

1 Health belief model and Carbohydrate, Lipids & Proteins Metabolism in BATCHES
explanatory Mode Starvation and Diabetes mellitus surface anatomy of abdomen
Name of faculty Venue Name of faculty Venue Name of faculty Venue
REVISION REVISION:
GROSS ANATOMY BIOCHEMISTRY
ANATOMY SELF-
2 ANAL CANAL
Peritoneum 1 STUDY HMP SHUNT
REVISION
BIOCHEMISTRY
Body Energy Gradient HISTOLOGY SELF-STUDY
3 Maintenance Anal Canal
(Electron Transport Chain & Name of faculty Venue
Oxidative Phosphorylation)
Name of faculty
Venue
REVISION GROSS ANATOMY: Lymphatic

ANATOMY RADIOLOGY drainage of Abdomen
4 Peritoneum 2 Assessment of GIT(PLAIN X RAY & SELF- Name of faculty Venue
Name of faculty BA STUDIES) STUDY
8:30-10AM 10-11:30AM
5 RADIOLOGY CLINICAL FACULTY SELF-
ASSESMENT OF GIT(CT SCAN) Hernia STUDY
REVISION
Biochemistry 10:30-11:30AM
Metabolism of bilirubin &Bile salt RADIOLOGY
6 SELF-STUDY
synthesis Assessment of GIT by ultrasound
(Uronic Acid pathway & role of
glucuronate)
369
GIT AND LIVER ,TIME TABLE 8TH WEEK
11:30 ----
Days 08-:30 ---- 10:00 10:30 ----- 11:30 1:30 ----- 03:00
12:30
CLINICAL FACULTY REVISION

1 Liver function tests BIOCHEMISTRY
Self-study
Name of faculty Venue Gluconeogenesis
REVISION
BIOCHEMISTRY
CLINICAL FACULTY
2 Role of glycogen in well fed, fasting,
Fatty liver disease starvation and malnutrition states
Name of faculty Venue (Glycogenesis&Glycogeno-lysis)
REVISION
BIOCHEMISTRY: REVISION
Amino acid degradation BIOCHEMISTRY
3 and synthesis, Fate of Dietary Cholesterol and College Closed at 01:00pm
indigenous Cholesterol in human body If first Ramadan
Urea cycle and metabolism (Metabolism of Cholesterol)
of ammonia Name of faculty Venue
4
SELF-STUDY
5 SELF-STUDY
6
Module exam
370
LEARNING OBJECTIVES
objectives:
ANATOMY
GIL1 Ang 1: Introduction & divisions of GIT + abdominal quadrants
Describe the divisions of GIT & abdominal quadrants

Define and list components of gastrointestinal tract
GIL1 Ang 2: Division of abdomen into regions and quadrants and their contents
Describe the Division of abdomen into regions and quadrants

Enlist the contents of abdominal regions
GIL1 Ang 3: surface anatomy of abdomen
Identify surface marking of stomach, spleen, liver, gall bladder, kidney & appendicular
orifice.
GIL1 Ang 4: Anterior abdominal wall
Describe the details of anterior abdominal wall.

Identify the layers of abdominal wall.
Identify the fascia, muscles of wall.
GIL1 Ang 5: Nerves of abdomen
Describe nerve supply of anterior and posterior abdominal wall.

Identify & create a visual representation of nerves supplying the abdomen.
Sequence and catagorize information on the segmental sympathetic supplies and referred
pain.
Explain the basic structure of paravertebral plexuses.
Describe somatic nervous supplyof abdomen.
GIL1 Ang 6: Inguinal Canal
371
Identify Surface marking of inguinal canal
Describe Walls of Inguinal Canal
Describe Deep Inguinal Ring & Superficial Inguinal Ring
Identify Structures passing through the inguinal canal
Enlist Coverings of spermatic cord
Explain Mechanics of the inguinal Canal
Define hernia and describe types of hernia namely Direct & indirect Inguinal Hernia
GIL1 Ang 7: Overview of peritoneal cavity and peritoneal relations + vertical disposition
Define peritoneum
Understand the different folds of peritoneum.
Discuss the embryological development of peritoneum and its folds
Describe greater and lesser sacs
List the intra and retroperitoneal viscera
Discuss vertical tracings of peritoneum
GIL1 Ang 8: Peritoneum- horizontal disposition
Describe peritoneum
Describe arrangement of peritoneum in transverse section of abdomen
Describe arrangement of peritoneum in transverse section of male pelvis
Describe arrangement of peritoneum in transverse section of female pelvis
GIL1 Ang 9: Lumbar vertebrae
Explain general characteristics of lumbar vertebrae including body and arch of lumbar
vertebrae
Describe processes like superior and inferior articular, transverse, spinous, mammillary
accessory processes
Describe first lumbar vertebra & fifth lumbar vertebra
Discuss lumbar spinal stenosis
GIL1 Ang 10: Posterior abdominal wall (boundaries, Muscles, fascia)
Identify structures forming posterior abdominal wall.

Describe muscles of posterior abdominal wall.
Identify attachments of lumber fascia.
GIL1 Ang 11: Lymphatic drainage of Abdomen
372
List the types of lymph nodes draining the abdomen
List the lymphatics draining the abdominal wall & the abdominal viscera
Identify the terminal group of lymph nodes around abdominal aorta
Describe the lymphatic trunks, cisterna chili & the thoracic duct
GIL1 Ang 12: Esophagus (abdominal part), stomach
Explain gross features of abdominal part of esophagus & stomach.

Name their peritoneal & visceral relations.
Explain their blood supply, lymphatic drainage & nerve supply.
GIL1 Ang 13: Duodenum and pancreas
Identify duodenum
Describe all the division of duodenum
Identify the relations of different parts of duodenum
Explain the details of pancreas.
Identify the parts and relations of pancreas
GIL1 Ang 14: Small Intestine & large intestine+ (comparison of two)
Describe the basic anatomy of small &large intestine

Identify the important gross features of large intestine
Explain the basic gross features which differentiate large intestine from small intestine
Identify the appendix on the basis of its distinguished features
Describe the characteristics of ano-rectal regions
GIL1 Ang 15: Abdominal aorta+ blood supply of abdomen
Describe the position and the vertebral levels of aorta in the abdomen.
List the main branches of the aorta and its territories.
Explain the applied anatomy of the aorta.
GIL1 Ang 16: Inferior vena cava+ venous drainage of abdomen

Describe the formation of inferior vena cava
List the tributaries of inferior vena cava

Explain abdominal and thoracic relations of this vein
Discuss clinical importance of inferior vena cava
373
GIL1 Ang 17: Liver
Describe the anatomical structure of liver.

Identify lobes and surfaces of liver.
Identify the segments of liver.
GIL1 Ang 18: Gall bladder and biliary tract
Describe the location, size, relation and blood supply of gallbladder

Explain differences between Intra & Extra Hepatic Billiary Systems
List different components of Extra-hepatic biliary System
Identify the right & left hepatic ducts, common hepatic duct, cystic ducts, bile duct
Describe clinical conditions related to gallbladder
GIL1 Ang 19: Hepatic portal system
Describe the hepatic portal circulation.

Explain the anatomy of hepatic vein.
Describe the portacaval anastomosis.
Explain the clinical correlation of hepatic portal system.
GIL1 Ang 20: Anal canal
describe gross anatomy of Anal Canal

explain the relations of the anal canal with the surrounding structures
describe the Blood supply, venous and lymphatic drainage of anal canal& innervations
of anal canal
EMBRYOLOGY
GIL1 Ane 1: Derivatives of foregut
Describe the divisions of primitive gut.

Describe the derivatives of foregut.
Describe the development of the derivatives of foregut.
Describe the applied anatomy of derivatives of foregut.
374
GIL1 Ane 2: Derivatives of mid and hind gut
Describe the derivatives of midgut.

Explain the rotation of midgut.
Describe Know the fixation of intestine.
Describe derivatives of hindgut.
Describe the clinical correlation of mid and hind gut.
GIL1 Ane 3: Congenital anomalies of gut
Describe the congenital anomalies of gut

Enlist the special features associated with common anomalies related to gut including:
Cleft lip or cleft palate
Hernias
Esophageal atresia
GIL1 Ane 4: Congenital anomalies of gut
Describe the congenital anomalies of gut

Enlist the special features associated with common anomalies related to gut including:
malrotation of gut
Anorectal malformations
GIL1 Ane 5: Development of liver, gall bladder and pancreas
Explain the hepatic and cystic buds

Discuss the site and source of parenchymal and stromal tissue of liver and gall bladder.
Explain the origin of pancreatic buds and their derivatives in adult pancreas
Explain congenital anomalies of liver, gall bladder and pancreas.
HISTOLOGY
GIL1 Anh 1: General plan of G.I.T + esophagus
Give overview of digestive system
Describe structure of the gastrointestinal tract, GIT
Explain histological features of layers of GIT
Describe Histological featuresof structure of each layer of esophagus
GIL1 Anh 2: Histology of Stomach
Different regions of stomach, grossly and histologically

Explain various layers of the wall of stomach
375
Describe different glands and the various kind of cells present in them
GIL1 Anh 5: Small intestine
Identify the parts of small intestine.

Describe the histological features of different parts of small intestine.
GIL1 Anh 6: Histology of pancreas
Briefly review the gross anatomy of pancreas

Discuss the histological components of pancreas
Discuss the histological details of Parenchyma and Lobules (acini) of Pancreas
Discuss the Duct System of Pancreas
Describe the endocrine component of pancreas
GIL1 Anh 8: Large intestine
Describe the basic anatomy of large intestine

Identify the important histological features of large intestine
Explain the basic histological features which differentiate large intestine from small
intestine
Identify the appendix on the basis of its distinguished features
Describe the characteristics of anorectal regions
GIL1 Anh 9: Histology of liver and gall bladder
Identify histology of liver

Explain common liver disorders
Explain clinical manifestations of liver disorders.
Describe Gall bladder histology.
GIL1 Anh 10: Histology of gall bladder
Identify the important landmarks of liver,

describe the histological architecture of liver
Identify the structural details of hepatocytes, portal triad, hepatic sinus&hepatic lobule
GIL1 Anh 11: Histology of liver
Describe the different components of biliary tract
376
Identify the histological appearance of gall bladder
BIOCHEMISTRY
GIL1 Bio 3: Overview of exocrine functions of Liver and Pancreas related to micro and
macronutrients
Describe the importance of liver & exocrine pancreas in metabolism and digestion of
micro and macronutrients.
GIL1 Bio 5: Jaundice
Understand mechanism of Jaundice

Give classification of jaundice on the basis of conjugated and non-conjugated
GIL1 Bio 6: Role of glycogen in well fed, fasting, starvation and malnutrition states
(Glycogenesis &Glycogenolysis)
Describe the overall purpose of glycogenesis and glycogenolysis, their reactants and
products, their cellular localization, and their tissue distribution
Explain the contribution of glycogenesis and glycogenolysis to blood glucose regulation
during the fed state, the fasting state, and exercise
Describe the roles of glycogen synthase and branching enzyme in glycogenesis, and
predict the biochemical and potential clinical consequences in deficiencies of these
enzymes
Explain how glycogen synthesis and glycogenolysis are regulated by insulin, glucagon,
and catecholamines
Describe the roles of glycogen phosphorylase, debranching enzyme, and glucose 6-
phosphatase in glycogen breakdown, and predict the biochemical and potential clinical
consequences in deficiencies in these enzymes glucose 6-phosphatase
Compare and contrast the purpose and regulation of glycogenolysis in hepatocytes vs
skeletal muscle
GIL1 Bio 7: Glycogen Storage diseases
List different glycogen storage diseases

Describe the biochemical changes involved in glycogen storage diseases
explain clinical features, prognosis and treatment of various glycogen storage diseases
377
GIL1 Bio 8: Over view of Digestion and Absorption of carbohydrates, lipids and proteins
Understand the role of digestion, absorption, bioavailability and metabolism of

macronutrients.
Understand the interaction between macronutrients and intermediated metabolites.
GIL1 Bio 9: Overview of nitrogen metabolism (digestion& transport of amino acid into cell,
removal of nitrogen from amino acids)
Describe factors affecting nitrogen balance in health and disease.

Describe the role of gastric hormone gastrin and paracrine hormone histamine in
promoting secretion of HCl and pepsinogen, and the activation of pepsinogen to pepsin.
Describe pepsin action in the digestion of peptides.
Describe the uptake of peptides and amino acids from the gastrointestinal tract.
GIL1 Bio 10: Degradation of dietary Lipids and their transport
List and explain the requirement of different lipases.

List the circulating forms of lipids found in various nutritional states.
Describe the fluxes of triglycerides and fatty acids between organs in the fed and fasted
states.
Describe the sites of synthesis and utilization of the various circulating lipids.
List the major products of fat oxidation.
Describe the major steps that regulate fat oxidation.
Explain how carnitine affects the partitioning of fat between oxidation vs. triglyceride
synthesis.
Explain what is different between the oxidation of unsaturated vs. saturated fatty acids.
GIL1 Bio 11: Malabsorption syndrome (biochemical background)
Define malabsorption
Describe causes and mechanism of malabsorption.
Explain commonest diseases associated with malabsorption
GIL1 Bio 12: Gluconeogenesis
Describe the 3 unique enzyme reactions for the gluconeogenic pathway and explain the
regulation of these reactions.
378
Discuss the contribution of fatty acid oxidation to the gluconeogenic pathway.
Describe the role of biotin and niacin in the gluconeogenic pathway.
GIL1 Bio 15: HMP shunt
Describe the general scheme of the pentose phosphate pathway
Explain the two stages of the pathway
Discuss the enzymes involved in the two cycles with special reference to the NADPH
production
Explain significance of the intermediates formed in the pathway
Describe the enzymes of the non-oxidative pentose phosphate pathway
Describe Wernicke-Korsakoff syndrome
GIL1 Bio 16: Metabolism of bilirubin & Bile salts synthesis
Describe the composition & function of Bilirubin

Explain the pathway of bilirubin metabolism
Describe the role of hemeoxygenase system
Explain Bilirubin conjugation in the liver
Explain Hyperbilirubinemias
Describe organic composition & flow of bile.
Explain synthesis of the bile acids from cholesterol & is regulation by its own feedback
inhibition & functions of bile salts
Understand the significance of glucuronic acid pathway
Describe the synthesis of glucuronic acid
Describe its conversion to ascorbic acid and pentoses
Discuss the role of UDP Glucuronic acid in synthesis of proteoglycans, drug metabolism,
xenobiotics
GIL1 Bio 17: Common Metabolic pathway for energy Provision from CHO, lipids and Amino
acids (TCA Cycle/ Krebs Cycle)
Describe steps of the TCA cycle & know the reactants and the products.
Relate the citric acid cycle in the role of generating energy.
Summarize the different reactions that occur during the cycle.
Give examples of condensation, dehydration, hydration, decarboxylation, oxidation and
substrate level phosphorylation.
Calculate the yield of ATP for one turn of the cycle.
Understand the reaction for the three enzyme complexes of pyruvate
dehydrogenase and how it is regulated and know which vitamins or cofactors are
involved in the PDH conversion of pyruvate to acetyl CoA.
379
GIL1 Bio 18: Body Energy Gradient Maintenance (Electron Transport Chain & Oxidative
Phosphorylation)
Define electron transport chain, oxidative phosphorylation, and coupling

List components of the respiratory chain and the electron carrying molecules. Know the
differences between the hemes.
Outline the pathway of electron transport in mitochondria in terms of the transfer of
electrons from the reducing equivalents to oxygen.
GIL1 Bio 19: Amino acid degradation and synthesis. Urea cycle and metabolism of ammonia
describe fate of amino acid carbons and the nitrogen

identify the organ involved in the urea synthesis
explain the reactions in the cytosol and the mitochondria
identify the basic amino acids involved in the urea cycle
explain the nitrogen acquiring reactions in the synthesis of urea
explain the links between the urea and the citric acid cycle
describe the fate of the urea
describe the rate limiting step of the urea cycle
GIL1 Bio 20: Carbohydrate, Lipids & Proteins Metabolism in well fed state and Obesity
Explain biochemical mechanisms of body adaption to obesity and in well fed state
regarding macronutrient metabolism
GIL1 Bio 21: Carbohydrate, Lipids & Proteins Metabolism in Starvation and Diabetes mellitus
Explain the normal production of ketone bodies &ketoacids

Define ketoacidosis & give common causes of ketoacidosis
Explain Diabetic ketoacidosis
Explain biochemical mechanisms of body adaption to starvation
GIL1 Bio 23: Phenyl Alanine, Tyrosine, Tryptophan, Methionine

Branch chain amino acids, Glycine, Histidine, Creatine&creatinine
Define ketogenic and glucogenic amino acids, and list them as exclusively ketogenic,
glucogenic, or both.
380
Distinguish disease states associated with Inborn Errors of Metabolism, including (A) the
deficient enzyme, (B) relation of the deficiency to the buildup of secondary metabolites,
and (C) clinically relevant information related to the disease state
Cystinuria
Histidinemia
Phenylketonuria
Methylmalonyl CoA mutase deficiency
Albinism
Homocystinuria
Alcaptonuria
Maple syrup urine disease
Cystathioninuria
Tyrosinemia
GIL1 Bio 24: Metabolic defects in protein/ amino acid metabolism
Describe the importance of dietary protein quality in the maintenance of health, and the
consequences of protein-energy malnutrition (e.g. Marasmus and Kwashiorkor).
GIL1 Bio 25: Coenzymes derived from vitamins and their role in metabolic actions
Define the role of the B vitamins in metabolism

Describe the components and functions of coenzymes NAD, FAD and coenzyme CoA
GIL1 Bio 26: Fatty Acids and Ketone body metabolism in human body
Define lipogenesis
Understand formation of malonylCoA
Understand acetyl CoA production and its utilization in fatty acid synthesis
Explain acetyl CoA carboxylase regulation
Explain the role of fatty acid synthase
Describe the 7 succession steps of fatty acid synthesis
Define major sources of NADPH and their use in fatty acid synthesis
Define triacylglycerol and its formation
Differentiate between ketonemia and ketonuria
Describe three forms of ketone bodies
Explain genesis of ketone bodies and the role of the liver
381
Describe transport of ketone bodies and the utilization of the ketone bodies and the
enzymes involved on ketogenesis
Define ketoacidosis the disease and physiological significance
GIL1 Bio 27: Fate of Dietary Cholesterol and indigenous Cholesterol in human body (Metabolism
of cholesterol)
List the major steps in the biosynthesis of cholesterol, emphasizing the regulatory sites.
List the pathways of cholesterol utilization.
Explain the importance of bile acid synthesis in cholesterol turnover.
Describe how the relative amount of cholesterol vs. carbohydrate could affect blood
cholesterol.
Understand the pathways of cholesterol biosynthesis and utilization, identify potential
secondary effects of HMG-CoA reductase inhibitors.
PHYSIOLOGY
GIL1 Phy1: Introduction to the digestive system
Understand the functional significance of the gastrointestinal system

Describe the structure of the gastrointestinal tract, the glands that drain into it, and its
subdivision.
List the major gastrointestinal secretions.
Identify the major hormones of the gastrointestinal system
GIL1 Phy2: Functions of smooth muscles and their electrical properties
Describe the characteristics of smooth muscle.

Explain the mechanism of smooth muscle contraction.
Give us the primary function of smooth muscle cells.
Give details of the electrical properties of smooth muscles.
Describe a few related disease conditions.
GIL1 Phy4: Nervous and hormonal control of GIT
382
Describe the importance of GIT.
Describe the gastrointestinal peptides.
Describe the control of digestive functions
by nervous system.
Define the term enteric nervous system
Describe the role played by the gastrointestinal hormones in gastrointestinal motility.
GIL1 Phy5: Motor functions of esophagus& stomach
Identify different parts of esophagus&stomach.

Describe the main functions performed by esophagus&stomach.
Explain the physiology of mixing and propulsion of food.
Define the term chyme
List and explain the factors that control gastric emptying.
Explain the control mechanism of gastric emptying.
GIL1 Phy7 :Movements of small and large intestine
Describe the small intestinal motility

Describe the functional parts of small intestine.
List 3 characteristics of the small intestine which increase the surface area.
Describe the physiological role of different colon regions
Explain the importance of peristalsis movements in large intestine
Describe the large intestinal motility.
GIL1 Phy8 :Salivary glands& secretion of Saliva
Describe Salivary glands, its secretion & functions of saliva.

Understand the Control of salivary secretion by Nerve supply.
Explain the Component of Saliva.
GIL1 Phy9 :Gastric secretion

List functions of stomach &Gastric glands,
Explain Structure of stomach wall
Describe composition and function of gastric secretions.
Explain Regulation of secretion mechanism of stimulating gastric secretion.
GIL1 Phy10: Small and large intestine secretions
383
Define Digestive system
Describe Digestive system secretions
Identify Component of small intestine
List and describe Intestinal secretions, Large intestine secretion & functions
Understand Neural control of digestive system&Integration of neural & hormonal
control
GIL1 Phy11: Bile secretion (composition, function and regulation)
Define bile
Describe the process of bile secretion
Explain why are bile saltsimportant especially for digestion
Understand entero-hepatic circulation
Describe clinical effect in the abnormalities of bile secretion
GIL1 Phy12: Pancreatic secretion

Understand Composition and function of pancreatic secretions.
Understand regulation of secretion mechanism of stimulating pancreatic secretion.
PATHOLOGY
GIL1 Pth 1: Malabsorption& celiac disease
Define Malabsorption
Describe the normal physiology of digestion and absorption in the GIT
Explain the pathophysiological mechanisms involved in malabsorption of nutrients
Explain the clinical features of malabsorption syndrome.
GIL1 Pth 2: Inflammatory Bowel Disease
Explain etiologies, pathogenesis, gross and microscopic changes & clinical presentations
of inflammatory bowel disease including Crohns disease and ulcerative colitis
GIL1 Pth 3: Circulatory disorders of liver
384
Describe the pathogenesis, clinical presentations, gross & microscopic pathological
features of diseases caused by:
Impaired blood flow into the liver due to hepatic artery compromise, portal vein
obstruction and thrombosis
Impaired blood flow through the liver causing cirrhosis & sinusoidal occlusion
Hepatic venous outflow obstruction as hepatic vein thrombosis and inferior vena
cava thrombosis & sinusoidal obstruction syndrome (veno-occlusive disease)
GIL1 Pth 4: Acute hepatitis
Explain etiology, pathogenesis, mode of transmission, clinical diagnosis of Hepatitis virus

A, Hepatitis virus B, Hepatitis virus D
GIL1 Pth 5: Chronic hepatitis & Cirrhosis

C, Hepatitis virus D
Explain Etiology, morphology & pathogenesis, gross &histo-pathological changes in
cirrhosis
GIL1 Pth 6: Motor disorders of esophagus, varices, esophagitis & Barretts esophagus
Explain Etiology, morphology & pathogenesis of motor disorders of esophagus,

esophageal varices, esophagitis & Barretts esophagus
GIL1 Pth 7: Acute & chronic gastritis
Explain the clinical presentations, etiologies, and pathogenesis, gross and microscopic
changes found in gastritis
GIL1 Pth 8: Diseases of salivary gland (non-tumors & tumors)
Describe xerostomia.
Explain pathogenesis, etiology, gross and microscopic changes of sialadenitis, mucocele,
and sialolithiasis
List and describe types, pathogenesis, etiology of salivary gland tumors.
385
GIL1 Pth 9: Peptic ulcer and H. Pylori infection association
changes found in peptic ulcers & H. pylori infection
Pancreatitis
GIL1 Pth 10:
changes found in acute & chronic pancreatitis.
PHARMACOLOGY
GIL1 Pha 1: Pharmacology- Anti-diarrheal drugs
Describe mechanism of action, side effects, adverse effects of pharmacological

management of diarrheas
GIL1 Pha 2: Pharmacology-Drugs used in constipation
Explain mechanism of action, types, side effects & adverse effects of drugs used in
constipation
GIL1 Pha 3: Drugs used as anti-emetic & pro-kinetic drugs
Describe mechanism of action, types, indications & side effects of anti-emetic drugs
Describe mechanism of action, types, indications & side effects of pro-kinetic agents
GIL1 Pha 4: Anti-secretory drugs: H2 antagonist
Explain mechanism of action, types, indications & side effects of H2 receptor antagonist
explain Triple & quadruple therapy
386
GIL1 Pha 5: Anti-secretory drugs: proton pump inhibitors & miscellaneous
Explain mechanism of action, types, indications & side effects of Proton pump inhibitors
explain Triple & quadruple therapy.
RADIOLOGY
GIL1 Rad 1: Radiology-Assessment of GIT (PLAIN X-RAY & BARIUM STUDIES)
Explain the x-ray and barium diagnostic tests for GIT evaluation
Identify the normal GIT diagnostic tests
GIL1 Rad 2: Radiology-Assessment of GIT (ULTRASOUND)
Explain the diagnostic tests for GIT evaluation

GIL1 Rad 3: Radiology-Assessment of GIT (CT SCAN)
Explain the diagnostic CT tests for GIT evaluation

SURGERY
GIL1 Sur 1: Hernias
Describe causes, pathogenesis, clinical presentation & complications of abdominal

hernias
MICROBIOLOGY
GIL1 Mic 1: Hepatotropic viruses

A, Hepatitis virus B, Hepatitis virus C, Hepatitis virus D, Hepatitis virus E.
387
GIL1 Mic 2: Diagnosis of H. pylori infection in clinical practice
Describe Helicobacter pylori infection

List relevant lab. Diagnostic tests
Describe significance of each relevant test
COMMUNITY MEDICINE
GIL1 Com 1: Study designs-1
Describe the different types of study designs

Understand the context in which different study designs are used
Differentiate between different study designs
Understand cross sectional and case-control studies
Explain cohort studies and randomized controlled trials
Illustrate the advantages and disadvantages of different study designs
Discuss some of the potential biases inherent in different study designs.
GIL1 Com 2: Study designs-2
Explain cohort studies and randomized controlled trials

Illustrate the advantages and disadvantages of different study designs
Discuss some of the potential biases inherent in different study designs.
GIL1 Com 3: How to conduct research
Understand what is research and why do we need to do it.

Describe the steps of conducting a research.
Identify different research methodologies.
Differentiate between the aim and objectives of a research.
Appreciate the value of literature review and research question.
Define the components of a research paper.
GIL1 Com 4: Dynamics of Diseases Transmission
388
Explain epidemiological triad of disease transmission
Describe factors effecting disease transmission
Define routes of transmission
Explain models of disease causation
Describe iceberg concept of infection
MEDICINE
GIL1 Med 1: Liver function tests
Identifytypes of enzymes in liver function tests

Describe significance of each relevant test with relation to hepatic & biliary system.
GIL1 Med 2:Fatty liver disease
Describe causes, pathogenesis, clinical presentation complications of fatty liver disease

Describe overview of management of fatty liver disease
BEHAVIORAL SCIENCES
GIL1 Beh1:Social support treatment stigma
GIL1 Beh 2:Social structure role and child rearing practices
GIL1 Beh 3:Family
GIL1 Beh 4:Health belief model and explanatory Model
389
GIT & Liver Module:
I. Introduction To Abdominal Examination
Diseases of gastrointestinal system are one of the common causes of morbidity and mortality
both in adults and children Abdominal examination is performed as an integral part of physical
examination, or when a patient presents with gastro intestinal problems (for example: Abdominal
pain, nausea, vomiting, diarrhea and GI bleeding ).
At the end of the session students should be able to:-
Enumerate the steps of examination of Abdomen.

To demonstrate correct technique of auscultation of Gut sounds.
II. NASOGASTRIC INTUBATION
Nasogastric intubation refers to the process of placing a soft plastic nasogastric (NG) tube
through a patient's nostril, past the pharynx and down the esophagus into a patient's stomach.
After the session students should be able to:
List the equipment/material required for NG intubation.

Demonstrate the appropriate technique for insertion n of nasogastric tube.
390
CASE BASED LEARNING
GIL1 Cbl1
Describe the anatomy of the GI tract
Understand the blood supply of the GI tract
Define is the reason of generalized abdominal tenderness
the risk factors for the disease

GIL1 Cbl2
Explain the gross and microscopic anatomy of liver
Give the arterial supply of organ involved
Give the hepatic causes of abdominal distension.
Explain the mechanism of development of abdominal distension.
Explain portal hypertension.
Enumerate the clinical consequences of portal hypertension?
GIL1 Cbl3
Students should be able to describe malabsorption.

Enlist the common and rare causes of malabsorption.
Enlist the series of investigations done to diagnose it.
Explain the management plan.
GIL1 Cbl4
Define pathophysiology of coeliac disease.

Describe the management outline of the given pathology.
Understand different anatomical structure involved in the process of Digestion and
Absorption of food.
Elaborate different causes of intestinal Malabsorption.
391
ROUND
WEEKS/HOURS 1 2 3 4 5 6 T1 T1x100/T2
OFF
ANATOMY 10 8.5 5 7 2.5 - 33 21.35 21
BIOCHEMISTRY 4.5 2.5 7.5 7.5 13 9 44 28.47 28
PHYSIOLOGY 6.5 3 2 - - - 11.5 7.44 7
PATHOLOGY 2 2.5 3 3 - - 10.5 6.79 7
PHARMA - 3 1 - - 2 6 3.88 4
MEDICINE - - - 1 1.5 - 2.5 1.61 2
BEHAVIORAL
- - - 1 2.5 1 4.5 2.91 3
SCIENCES
COMMUNITY
- - 1.5 1 1.5 1.5 5.5 3.55 3
MEDICINE
MICRO - 1.5 - 1 - - 2.5 1.61 2
HISTOLOGY 3.5 3.5 4 1.5 1.5 - 14 9.06 9
RADIOLOGY - - 1 1 1 - 3 1.94 2
SURGERY - - - - - 1 1 0.64 1
SKILL LAB 1.5 1.5 1.5 1.5 1.5 1.5 9 5.82 6
CBL - 1.5 1.5 1.5 1.5 1.5 7.5 4.85 5
TOTAL 28 27.5 28 27 26.5 17.5 154.5 100 100
392
GIT-1 MODULE
(SEMESTER-III)
SUMMATIVE ASSESMENT
THEORY

SEMESTER
ATP 25
EXAM
PAPER-I One best Questions

20
based on CBL
80%
Total 100
MODULE EXAM
EMQs 10
ATP 20
MODULE PAPER
20
based on CBL
Total 100
STRUCTURED VIVA

ASSESMENT
SUMMATIVE
SEMESTER
EXAM
See Semester
Assessment Plan
ASSESMENT TOOLS
Structured Feedback
Facilitator
NOTE: Paper II & IV-B of Semester-4 Examination are Based on Renal Module.
Paper III & IV-C of Semester-4 Examination are Based on Reproduction Module.
393
CREDIT HOURS
GASTROINTESTINAL TRACT & LIVER MODULE
SEMESTER- IV
GIL-1 MODULE
Paper-I 6
GIL-1
Paper-IV-A 3
394
RENAL 01 MODULE
(EXC 1)
SEMESTER IV
SECOND (2ND) YEAR M.B.B.S
395
Spiral Sem. Modules

II

4 Week
wks
Second th
Spiral th
Trauma, 6 week
3 week 8 Weeks
/ Burns 2 wk
2 Weeks
th
th
PARALLEL THEMES:
396
MODULE COMMITTEE
SPIRAL 01:
Prof. Naheed Khan, Professor of Anatomy, DMC

Dr. Rukhsana Rubeen, Associate Professor of Biochemistry, DMC
Dr. Kelash Nankani, Associate Professor of Physiology, DMC
Dr. Mahmood Hassan, Professor of Pathology, SMC
Dr. Farooq Alam, Lecture of Pharmacology, DIMC
Dr Mujtaba Kolachi, Associate Professor of Anatomy, DMC
Documented by:
Dr.Tanzeela Khan (Department of Anatomy, Dow Medical College, DUHS)
Coordinated by:
Dr.Ateeba Ayesha Khan (Department of Pathology, Dow Medical College, DUHS)
Reviewed by:
Module committee
397
RATIONALE
Renal system is involved in the excretion of waste products especially nitrogenous end
products of protein metabolism. It regulates normal hydrogen ion concentration, pH and acid
base balance, maintains sodium and potassium and electrolyte balance of the body also
maintain blood pressure, osmotic pressure, water balance, plasma / extra cellular fluid volume.
Renal diseases are common in the community and renal failure is a common end stage of most
renal disorders. Understanding of the basic anatomy, physiology and biochemical processes is
essential for dealing with the disease processes afflicting the renal system. This module
provides this basic understanding.
TERMINAL OBJECTIVES
Discuss anatomy of kidney and urinary tract

Review embryological development of kidney and urinary tract
Explain common developmental abnormalities of renal system
Identify role of renal system in maintaining blood pressure and acid base
balance
Enlist functions of kidney and pathologies related to them.
Explain method of electrolyte balance and pathologies related to it.
Highlight pathologies related to kidneys and their distinctive clinical
features
Interpret investigations done to diagnose abnormal structural and
functional presentations.
398
Objectives of module are listed in following grid along with contents, modes of information
transfer, duration of teaching of each content and the mode of assessment.
spotting
Practical /
DIGITAL LIBRARY
One Best, EMQS

SELF STUDY
TUTORIALS
PRACTICAL
LECTURES
SKILL LAB
CBL/ SBL
LIBRARY
DEMOS
viva
LEARNING FACULTY TOPIC/CONTE
OBJECTIVES NT Assessment
EXC 1 Ang 1 1
ANATOMY
* *
Overview of
Excretory system
Describe the of the body and
structure and structure of
functions of kidney
excretory EXC 1 Phy 1 1
system PHYSIOLOGY
* *
General
functions of the
kidneys and
Excretory system
EXC 1 Bio 1 1
BIOCHEMISTRY
* *
Physicochemical
Aspects in
relation to water
(Diffusion,
Adsorption,
viscosity)
EXC 1 Ane 1 1
Explain the EMBRYOLOGY
* *
development of Development Of
kidneys and Kidney & Ureter
ureters with
399
their related EXC 1 Pth 1 1
anomalies
* *
PATHOLOGY
Anomalies of
kidney and lower
urinary tract
EXC 1 Anh 1 1
Describe the
* *
histological and Histological
gross features of Features of
kidneys and kidney (detailed
ureters with its microscopic
blood, lymphatic features of
and nerve nephron and
supply HISTOLOGY collecting ducts
EXC 1 Anh 2 1.5
* * *
Microscopic
features of
nephron and
collecting ducts
EXC 1 Ang 2 1 * *
Details of gross
anatomical
features of
kidney
ANATOMY EXC 1 Ang 3 1 * *
Details of blood
and nerve supply
and lymphatic
drainage of
kidney
EXC 1 Bio 2 1 * *
Osmolality,
osmolarity,
tonicity,
Colloid osmotic
pressure
(oncotic
Describe the pressure ),
BIOCHEMISTRY
biochemical Osmosis and role
and
of albumin
physiological
400
aspects of GFR EXC 1 Bio 3 1.5
* * *
and role of pH
and water Normal,
hypertonic,
hypotonic
solutions
EXC 1 Phy 2 1
PHYSIOLOGY
* *
GFR and factors
affecting GFR
EXC 1 Phy 2
*
Tubular Re-
absorption and
secretion
EXC 1 Bio 4 1 * *
BIOCHEMISTRY
The role of water
and Ph
SKILL LAB 1.5

Hands on session *
on urinary
catheterization

Recognize the Gross anatomical
features of ureter,
normal gross urinary bladder
structure of and
ureter, urethra(male&
female)
urinary
bladder and EXC 1 Anh 3 1 * *
urethra
including Histological
features of ureter,
topographical
urinary bladder
anatomy, its and urethra
blood supply, HISTOLOGY
nerve supply EXC 1 Anh 4 1.5
*
and
Ureter, urinary
histological bladder and
features urethra

Blood supply,
lymphatic
drainage
and nerve supply
401
of ureter and
urinary bladder
and urethra
including these
organs
EXC 1 Ane 2 1
Describe the
* *
Development of
development urinary bladder
of and
urinary EMBRYOLOGY
urethra
bladder and
EXC 1 Ane 3 1
urethra with * *
its related Anomalies
anomalies of bladder &
urethra
EXC 1 Bio 5 1 * *
Recognize the Role of Renal
concept of System
in acid base
electrolyte balance
balance and
imbalance and
its correlation EXC 1 Bio 10 1.5
with other
* *
systems and its Acid base balance,
BIOCHEMISTRY buffers, alkalosis
importance.
(Biochemistry:
EXC 1 Bio 6 1
pH, acid base * *
balance, Sodium and
buffers, chloride
alkalosis, Metabolism
acidosis )
ANATOMY EXC 1 Ang 6 1

Perform the
* *
surface Surface Anatomy
of Urinary
marking of
System
urinary system
PATHOLOGY EXC 1 Pth 2 1
Describe the
* *
pathogenesis Pathogenesis of
glomerular
of glomerular disorders
diseases
402
PHYSIOLOGY EXC 1 Phy 3 1
Discuss
* *
Formation of The concentration
and dilution of
urine, re- Urine
absorption and
EXCretion of
urine.
Discuss the PHYSIOLOGY EXC 1 Phy 4 1

* *
importance of
Acidification of
concentration urine
and dilution of
urine,
acidification of
urine
EXC 1 Phy 5 1.5
Comprehend PHYSIOLOGY * *
the concepts GFR Regulation
and Importance
of GFR and their
regulating
factors
EXC 1 Bio 7 1
* *
Discuss Potassium and
Phosphate
normal and Metabolism
abnormal
constituents EXC 1 Bio 8 1
of urine in
* *
Nucleic acid
relation with BIOCHEMISTRY
Purine
phosphateuri Metabolism
a, glycosuria,
and amino EXC 1 Bio 9 1
* *
acid urea and
Disturbances of
interpret the water, sodium and
biochemical potassium balance
reports.
CLINICAL EXC 1 Med 1 1 1.5
FACULTY Urine detailed
* *
report
sample collection
and
biochemical
analysis
403
PHARMACOLOGY EXC 1 Pha 1 1
Classify
* *
diuretics Overview Of
Diuretics
related to their
site of action
and their 1.5
adverse effects CASE BASED EXC 1 Cbl 1
* *
LEARNING
EXC 1 Bio 10 1
Describe the
* *
biochemical Purine
metabolism 2
aspects of
purine
EXC 1 Bio 11 1
metabolism BIOCHEMISTRY * *
with its related Disorders of
disorders purine
metabolism
EXC 1 Pth 2 1
* *
Explain the Nephritic
pathogenesis PATHOLOGY syndrome
of nephritic
EXC 1 Pth 3 1
and nephrotic * *
syndrome
Nephrotic
syndrome
PHYSIOLOGY EXC 1 Phy 6 1

Process of
* *
Discuss the micturition and
process of micturition reflex
micturition
and
micturition
reflex
MEDICINE EXC 1 Med 2 1

Interpret the
* *
ABG reports for Interpret the ABG
the diagnosis of reports for the
acidosis and diagnosis of
acidosis and
alkalosis
alkalosis
Describe the
* *
pathogenesis of Tubulointerstitial
tubulointerstitia diseases
404
l diseases and EXC 1 Pth 5 1
Pyelonephritis PATHOLOGY
* *
Pyelonephritis
1
Explain the BIOCHEMISTRY EXC 1 Bio 12
* *
relation of urea
uric acid, Relation of urea
creatinine, uric acid,
calcium and creatinine,
calcium and
albumin and
albumin and other
other
electrolytes with
electrolytes with renal disorders
renal disorders
EXC 1 Bio 13 1
Relate BIOCHEMISTRY
* *
pyrimidine Pyrimidine
metabolism metabolism
with renal
functions
EXC 1 Med 3 1
Recognize the
* *
importance of Renal failure
clinical picture
dialysis in the
and presentation
cases of renal MEDICINE
EXC 1 Med 4 1
failure
Dialysis types and
* *
importance
Discuss the EXC 1 Pth 5 1

PATHOLOGY
* *
pathogenesis
Lower urinary
of lower tract infections
urinary tract
infections
EXC 1 Med 4 1
Discuss the MEDICINE
* *
dehydrated and Dehydration/ over
overhydrated hydration
conditions conditions
EXC 1 Med 5 1
Interpret the RADIOLOGY/
* *
radiographs of CLINICAL Radiographs and
urinary system other imaging
techniques of
urinary system
405
PRACTICALS: PHYSIOLOGY EXC 1 Phy 7
1.5
* *
Regulation of
Hormonal
water and
regulation of
electrolyte water and
balance by electrolytes
various
hormones (ADH,
Aldosterone,
rennin, etc.
Abnormalities:
Hyper-
aldosteronism,
Diabetes
Insipidus).
Define the BIOCHEMISTRY EXC 1 Bio 14

1.5 * * *
Plasma
Discuss the
clearance and its
normal
relation with
constituents of
clinical disorders
urine Renal
function tests
(plasma clearance)
CASE BASED EXC 1 Cbl 2 1.5 * *

LEARNING
406
DATES, TEACHING FACULTY AND VENUES SHOWN IN ITALICS ARE SUBJECTED TO CHANGE
DOW UNIVERSITY OF HEALTH SCIENCES
SEMESTER IV- RENAL MODULE - FIRST WEEK
10:00------11:00
Days 08:30------10:00 11:00------12:00 12:00-------1:00
1-A=Histology Practical :microscopic

features of nephron and collecting ducts
Biochemistry
2-B=Biochemistry Practical Solutions: Anatomy Overview of EXCretory Physiology
Physicochemical Aspects in
hypotonic and hypertonic, Molal, molar, system of the body and structure of General functions of the
relation to water
Normal Solutions, Use of normal saline kidney kidneys and excretory
1 (Diffusion, Adsorption,
Name of Faculty Venue system
viscosity)
Name of Faculty
Venue Venue
Venue
3-C1=Skill lab: Hands on session of Urinary
Catheterization in SKILL LAB
C2=SELF STUDY
4-D=SELF STUDY
BIOCHEMISTRY:
Osmolality, osmolarity,
1=B Anatomy Histological: tonicity, Anatomy Demo
Features of kidney: (detailed Colloid osmotic pressure
2=C 4batches
microscopic features of nephron and (oncotic pressure ),
2 Details of gross anatomical
3=D collecting ducts
Osmosis and role of features of kidney
Name of Faculty
4=A albumin Venue
Venue
Name of Faculty
Venue
Anatomy Demo 4 batches

Details of blood and nerve
1=C supply and lymphatic drainage
PHYSIOLOGY BIOCHEMISTRY
2=D GFR and factors affecting GFR The role of water and Ph of kidney
3 A+B= Name of Faculty Venue
3=A Name of Faculty Name of Faculty
C+D= Name of Faculty
4=B Venue Venue Venue
D= Name of Faculty
Venue
1=D
10-11:30 AM
2=A Anatomy
4 SELF-
Development Of Kidney & Ureter
3=B STUDY
Name of Faculty
4=C Venue
Anatomy Demo 4 batches

PATHOLOGY Gross anatomical features of ureter, urinary bladder and
PHYSIOLOGY:
Anomalies of kidney and lower urinary urethra(male& female)
Tubular Re-absorption and secretion
5 tract A+B+C= Name of Faculty
Name of Faculty
Venue
Venue D+E= Name of Faculty
Venue
407

RENAL MODULE - SECOND WEEK
Days 08:30------10:00 10:00------11:00 11:00------12:00 12:00-------1:00
Anatomy demo 5 batches

Blood supply, lymphatic drainage and
Anatomy nerve supply of ureter and urinary
Biochemistry bladder and urethra including these
Histological B.S
Role of Renal System in
features of ureter, urinary bladder and Counseling organs
1 acid base balance
urethra Name of Faculty A+B+C= Name of Faculty
Name of Faculty
Name of Faculty Venue Venue
Venue
Venue D+E= Name of Faculty
Venue
1-A=-Physiology Tutorial: GFR

Regulation Name of Faculty
Venue
2-B=Biochemistry PracticalAcid base
balance, buffers, alkalosis, acidosis Name
of Faculty Anatomy demo 5 batches
Anatomy Biochemistry Surface Anatomy of Urinary system
Venue Sodium and chloride
Development of urinary A+B= Name of Faculty
2 3-C1=Skill lab: Hands on session of bladder and urethra metabolism Venue
Urinary Catheterization in Skill Lab Name of Faculty Name of Faculty C+D= Name of Faculty
C2=SELF STUDY Venue Venue Venue E= Name of Faculty
Venue
4-D=CBL
5.E=Histology practical: ureter, urinary
bladder & Urethra
Name of Faculty
Venue
1. B PATHOLOGY
Anatomy Anomalies of Physiology
2. C Pathogenesis of
bladder & urethra the concentration and dilution of urine
3 3. D glomerular disorders
4. E Name of Faculty
Venue Venue
5. A= Venue
Biochemistry
1. C Biochemistry Disturbances of water, sodium and
2. D Potassium and Phosphate PHARMACOLOGY potassium balance
4 3. E Metabolism Overview Of Diuretics Name of Faculty
4. A Name of Faculty Name of Faculty
Venue
5. B= Venue Venue
1. D 10-11:30AM
2. E Physiology
5 3. A Acidification of urine
4. B Name of Faculty
5. C= Venue
. CLINICAL FACULTY
1. E
B.S Urine detailed report Biochemistry:
2. A
Informational Care sample collection and Nucleic acid Purine Metabolism- 1
6 3. B
Name of Faculty biochemical analysis Name of Faculty
4. C
Venue 2 Name of Faculty Venue 2
5. D=
Venue
408

RENAL MODULE THIRD WEEK
Days 08:30------10:00 10:00------11:00 11:00------12:00 12:00-------1:00
1-A=-Physiology Tutorial:
Hormonal regulation of water and
electrolytes Name of Faculty
Venue
2-B=Biochemistry Practical
Discuss normal constituents of urine Biochemistry PATHOLOGY Physiology
Renal Function Tests (Plasma clearance) Purine Metabolism Nephritic syndrome Process of micturition
1 Name of Faculty 2 and micturition reflex
Venue Name of Faculty
Venue
Venue Venue
3-C2=Skill lab: Hands on session of
Urinary Catheterization in SKILL LAB
C1=SELF STUDY
4-D=CBL
5.E=SELF-STUDY
MICROBIOLOGY Biochemistry
1. B Urine detailed report
2. C Disorders of Purine
sample collection and
2 3. D Metabolism SELF STUDY
biochemical analysis
4. E
5. A Venue
Venue
MEDICINE
1. C Interpret the ABG
PATHOLOGY
2. D reports For the
Nephrotic syndrome
3 3. E diagnosis of acidosis
Name of Faculty
4. A and alkalosis
5. B Venue Name of Faculty
Venue
Biochemistry
Radiology
Relation of urea uric
1. D PATHOLOGY Radiographs
acid, creatinine, calcium
2. E Tubulointerstitial + other imaging
and albumin and other
4 3. A diseases Name of techniques of urinary
electrolytes with renal
4. B Faculty system
disorders
5. C Venue Name of Faculty
Venue
1. E Biochemistry MEDICINE
2. A Pyrimidine Renal failure clinical
5 3. B Metabolism picture and presentation
4. C Name of Faculty Name of Faculty
5. D Venue Venue
MEDICINE
Dehydration/ over-hydration: ORS +other
Available solutions for Intra venous MEDICINE PATHOLOGY
PATHOLOGY
infusions(Dextrose water5%, 10 %, 25%, Dialysis types and Lower urinary tract
Pyelonephritis
6 importance infections
Ringerlactate, Normal saline, amino acids Name of Faculty
solutions, Hemaxcel Name of Faculty Name of Faculty
Venue Venue
Venue
409
LEARNING OBJECTIVES
At the end of the lecture, students should be able to:
ANATOMY
EXC 1 Ang 1 OVERVIEW OF EXCRETORY SYSTEM OF THE BODY AND STRUCTURE OF KIDNEY
Describe the different parts of EXCretory system.

Describe the general overview of these EXCretory parts.
Explain the structure of kidney.
EXC 1 Ang 2 GROSS FEATURES OF KIDNEY
Describe the gross features of kidney
Differentiate the anterior and posterior surfaces and relations of kidney
Identify the internal structure of kidney
EXC 1 Anh 1 HISTOLOGICAL FEATURES OF KIDNEY.

(MICROSCOPIC FEATURES OF NEPHRON AND COLLECTING DUCTS)
Summarize the anatomy of kidney.
Describe the detailed microscopic features of nephron and collecting ducts.
EXC 1 Ang 3 BLOOD SUPPLY, INNERVATION, LYMPHATIC DRAINAGE & SURFACE

ANATOMY OF KIDNEY
Describe the blood Supply of Kidney
Describe the Lymph nodes draining the kidney
Explain the Nerve supply of Kidney
410
Perform the Surface anatomy of the kidney on human bony landmarks
EXC 1 Ane 3 ANOMALIES OF KIDNEY AND URETER
Identify clinical conditions related to kidney and ureter
Differentiate between the congenital abnormalities and pathological conditions of

kidney and ureter.
EXC 1 Ang 4 GROSS ANATOMY OF URETERS, URINARY BLADDER AND URETHRA
Identify ureter, urinary bladder and urethra
Describe the course and relations of ureter
Explain the parts and relations of urinary bladder
Identify the parts of urethra
EXC 1 Anh 3 HISTOLOGY OF URETER AND URINARY BLADDER & URETHRA
Describe the location of the ureter & urinary bladder
Explain the histology of
Ureter,
Urinary bladder and Urethra
BLOOD SUPPLY, LYMPHATIC DRAINAGE & NERVE SUPPLY OF URINARY BLADDER,

EXC 1 Ang 5
URETER & URETHRA
Describe the blood supply of urinary bladder, ureter & urethra.
Explain the Lymphatic drainage of urinary bladder, ureter & urethra.
Describe the Nerve supply of urinary bladder, ureter & urethra.
411
EXC 1 Ane 2 DEVELOPMENT OF URINARY BLADDER AND URETHRA
Describe the development of urinary bladder.
Explain the development of urethra.
Describe the congenital anomalies related to them.
EXC 1 Ang 6 SURFACE ANATOMY OF URINARY SYSTEM
Identify the surface anatomy of
Kidney,
Ureter and
Urinary bladder.
EXC 1 Ane 3 ANOMALIES OF URINARY BLADDER AND URETHRA
Describe the congenital anomalies of urinary bladder.
Explain the congenital anomalies of urethra
PHYSIOLOGY
EXC 1 Phy 1 GENERAL FUNCTIONS OF THE KIDNEYS AND EXCRETORY SYSTEM
Define parts of the EXCretory System.

Explain the Histology of the Functional unit Nephron.
Enlist the Primary functions of the Kidneys.
Describe the process of achieving the functions.
EXC 1 Phy 2 GFR ,FACTORS AFFECTING IT & ITS REGULATION:
412
Describe glomerular filtration membrane and how it EXCludes blood cells and proteins
from the filtrate
Explain the forces that promote and oppose glomerular filtration
Discuss how will you calculate net filtration pressure if given the magnitude of these
forces
Define glomerular filtration rate (GFR) and discuss Factors affecting GFR
Explain the regulation of GFR (describe how the nervous system, hormones, kidney itself
regulate glomerular filtration).
EXC 1 Phy 3 TUBULAR REABSORPTION
Describe the general structure of tubular system
Describe the tubular reabsorption at different renal segments
Effect of tubular reabsorption on concentration of urine
Explain the role of ADH and urea
EXC 1 Phy 5 ACIDIFICATION OF URINE
Outline the processes involved in the secretion of H+ into the tubules.
Discuss the regulation of acidbase balance.
Define acidosis and alkalosis, and give the normal mean and the range of H+
concentrations in blood.
Describe the changes in blood chemistry that occur during the development of
metabolic acidosis and metabolic alkalosis.
EXC 1 Phy 6 PROCESS OF MICTURITION AND MICTURITION REFLEX
Enlist the organs of micturition
Describe the neural control of micturition
413
BIOCHEMISTRY
EXC 1 Bio 1 PHYSICOCHEMICAL ASPECTS IN RELATION TO WATER
Discuss the importance of water in our life
Define the Homeostasis of water
Explain the Fluid compartments in the body
Describe the Hydrogen bonding in water and its importance in the movement
Define the terms diffusion, adsorption and viscosity
EXC 1 Bio 2 OSMOLARITY, OSMOLALITY, TONICITY, COLLOID OSMOTIC PRESSURE

OSMOSIS AND ROLE OF ALBUMIN
Define the terms osmolality, osmolarity and tonicity
Describe osmosis
Justify the role of albumin in maintaining plasma oncotic pressure
EXC 1 Bio 4 Role of Water & Ph
Describe the Biomedical Importance of water and pH.
Describe the characteristics of water.
Explain the formation of hydrogen bonds by water molecule.
Describe the Van der Waals forces.
EXC 1 Bio 5 ROLE OF RENAL SYSTEM IN ACID BASE BALANCE
Define acidosis and alkalosis
414
Explain the role of Buffers in maintaining acid base balance
Enlist different causes of these conditions
Describe the mechanism of development of acidosis and alkalosis
Enlist the biochemical changes in these conditions
EXC 1 Bio 6 SODIUM AND CHLORIDE METABOLISM
Describe the different sources of sodium & Chloride
Enlist different functions of sodium & Chloride
Justify their role in maintaining the osmolality of plasma
Interpret the Normal values of sodium & chloride in serum and urine
EXC 1 Bio 7 POTASSIUM & PHOSPHATE METABOLISM
Enlist sources of potassium & Phosphates
Justify the role of potassium PO4 in maintaining active life
Give their RDA
EXC 1 Bio 8 NUCLEIC ACID - PURINE METABOLISM
Explain the pathway of Purine synthesis.
Discuss the role of various amino acids in the synthesis of AMP and GMP.
Describe the role of folic acid and CO2 in the synthesis AMP and GMP
EXC 1 Bio 9 DISTURBANCES OF WATER, SODIUM AND POTASSIUM BALANCE
Describe normal intake/ output of water, Na & K
Explain the sources of water, Na & K
415
Discuss the Role of kidney and hypothalamus
Discuss the Role of ADH & aldosterone
MEDICINE
EXC 1 Med 1 URINE DETAILED REPORT COLLECTION AND EXAMINATION
Enlist the precautions necessary to collect the urine sample for Urine detailed report
examination
Discuss the various components of urine analysis
Describe the importance of each of the components in relation to different disease

states
EXC 1 Med 2 DEHYDRATION / OVER-HYDRATION CONDITIONS
Define Dehydration.
Classify dehydration
Discuss the treatment plans in mild, moderate and severe dehydration
Describe rehydration.
Explain the composition of ORS.
Discuss other Intravenous solutions that can be used as volume expanders
EXC 1 Med 3 RENAL FAILURE
Describe an overview of anatomy, physiology of urinary system.
Explain the classification of renal failure.
416
Discuss the clinical picture and presentation of renal failure.
PATHOLOGY
EXC 1 Pth 1 TUBULO INTERSTITIAL DISEASES:
Define Tubulo interstitial injury.
Describe causes & pathogenic mechanisms of Tubulo interstitial injury.
Identify predisposing factors of Pyelonephritis.
Describe causes, pathogenic mechanisms & morphology of Acute Pyelonephritis.
Describe clinical course of Acute Pyelonephritis.
Identify features of Chronic Pyelonephritis.

Renal and excretory Module:
I. MALE AND FEMALE URETHERAL CATHETERIZATION
Urethral catheterization is an invasive procedure with several potential hazards if not performed
proficiently, like trauma to the urethera and infection. It is imperative that all health professionals
be thoroughly versed with the procedure.
After the session students should be able to:
List the equipment required for the procedure.
Demonstrate correct aseptic techniques and the procedure for urinary catheterization
in males & females.
417
CASE BASED LEARNING
EXC 1 Cbl 1
The anatomaical correlate of obstructive conditions of urinary tract
Classification of obstructive Disorders of urinary tract
The signs and symptoms of urinary tract obstruction
Be able to understand the significance of hematuria, bacteriuria and leukocyturia in a

patient with history suggestive of renal colic
Be able to understand the chemical composition of renal stones.
EXC 1 Cbl 2
Describe the anatomical relations of right and left kidneys
Identify different causes of flank pain
Corelation of hypertension and kidney diseases
418
TABLE OF SPECIFICATION
WEEKS 1 2 3 TOTAL (TI) T1x100/T2 ROUND OFF
ANATOMY 3 7 - 10 17.09 18
BIOCHEMISTRY 4.5 6.5 5.5 16.5 9.65 10
PHYSIOLOGY 5 4 2.5 11.5 19.65 20
PATHOLOGY 1 1 5 7 11.96 12
MICRO - - 1 1 1.70 2
PHARMA - 1 - 1 1.70 2
MEDICINE - 1 4.5 5.5 9.40 10
BEHAVIORAL
- 2 - 2 3.41 4
SCIENCES
RADIOLOGY - - 1 1 1.70 2
SKILL LAB 1.5 1.5 3 5.12 6
CBL - 1.5 1.5 3 5.12 5
TOTAL (T2) 13.5 24 19.5 58.5 99.05 100
419
RENAL & EXCERTORY SYSTEM-1 MODULE
(SEMESTER-IV)
SUMMATIVE ASSESMENT
THEORY
SEMESTER
ATP 25
EXAM
PAPER-II One best Questions 80%

20
based on CBL
Total 100
MODULE EXAM
EMQs 10
ATP 20 20%
MODULE PAPER
One best Questions
20
based on CBL
Total 100
STRUCTURED VIVA

ASSESMENT
SUMMATIVE
SEMESTER
EXAM
See Semester
Assessment Plan
ASSESMENT TOOLS
Structured Feedback
Facilitator
NOTE: Paper I & IV-A of Semester 4 Examination are Based on GIT & Liver Module.
Paper III & IV-C of Semester 4 Examination are Based on Reproduction Module.
420
CREDIT HOURS
SEMESTER IV
RENAL & EXCRETORY SYSTEM-1 MODULE
Paper-II 3
EXC-1
Pper-IV-B 1.5
421
REPRODUCTION MODULE
Code: REP 1
Semester: IV
Second Year MBBS
422
Spiral Sem. Modules

II

4 Week
wks
Second th
Spiral th
Trauma, 6 week
3 week 8 Weeks
/ Burns 2 wk
2 Weeks
th
th
PARALLEL THEMES:
423
MODULE COMMITTEE
Dr. Farrukh Mustafa ,Assistant Professor of Anatomy, DUHS

Dr. Nighat Mannan, Professor of Physiology, DUHS
Dr. Zia Ikram Assistant Professor of Biochemistry, DUHS
Dr. Talat MIrza, Professor of Pathology, DUHS
Dr. Shamaila Khalid, Assistant Professor of Pharmacology, DUHS
Dr. Riffat Jaleel Assistant Professor of Gynae&Obs, DUHS
Dr. Rukhsana Rubeen Assistant Professor of Biochemistry, DUHS
Dr. Naheed Khan Professor of Anatomy, DUHS
Module Documented by:

DR. ARISHA SOHAIL
Coordinated by:
DR. ATEEBA AYESHA KHAN
Reviewed by:
Modular committee
424
RATIONALE:
Reproduction module enables students to relate the knowledge of anatomy,

physiology and pathology of the structures of the male and female
reproductive system with the clinical presentation of internal and external
genital diseases in order to manage general gynecological problems, sexually
transmitted infections, infertility, tumors, breast disorders, pregnancy and
related issues in the mother and neonates.
TERMINAL OBJECTIVE:
Describe the anatomy of male and female reproductive organs.

Discuss the development of reproductive organs and their related
embryological disorders.
Explain role of various hormones on male and female reproductive
system.
Identify stepwise synthesis and release of gametocytes and
pathologies related to it.
Define various terms used to describe pathological menstrual
bleeding.
Express the importance of breast feeding.
Highlight the role of pharmacological agents used to treat different
reproductive pathologies.
425

mode of assessment.
Digital library
BCQs, EMQs
Self
Skills Lab
Tutorials
Practical
Lectures
Teaching
Demo:
spottin
CBL
viva
ATP
Objectives
Study
Faculty
Content / Topic
Modes of information transfer Assessment

Rep 1 Ang 1Sacrum
Describe bony pelvis with &CoccyxJoints of 1 * * *
types, differentiate the pelvic cavity
boundaries of male &
female pelvis and their ANATOMY Rep 1 Ang 2
bony details Bony Pelvis(inlet
related to pelvic and outlet)
malformation correlating Difference b/w
them with anatomy male & female 1.5 * * *
pelvis
Types of bony
pelvisCephalopelvic
disproportion
Identify the boundaries and Rep 1 Ang 3
spaces of pelvic floor ANATOMY Pelvic walls
Pelvic floor 1.5 * * *
Pelvic fascia
Divisions of pelvis
Describe the different Rep 1 Ang 4
visceras / organs inside the Perineum:
pelvic cavity Divisions
(Urogenital 1 * * *
ANATOMY Diaphgram) of
perineum and
Perineal body
Rep 1 Ang 5
1.5
Anal Region * * *
Anal Canal
GROSS Rep 1 Ang 6
ANATOMY Male internal
genital organs: 1 * * *
Testes, epididymis,
Histology scrotum
Rep 1 Anh 1 Testes 1 1.5 * * *
426
Rep 1 Ang 7
GROSS Relative Anatomy
ANATOMY of pelvic organs
Pelvic sigmoid 1.5 * * *
Colon, Rectum,
Urinary Bladder
Identify the boundaries Rep 1 Ang 8
&recesses, know the ANATOMY Ischiorectal Fossae 1
details &contents of
Rep 1 UL * * *
ischiorectal fossa.
SKILL LAB Examination of
Introducing the concrpt of Rectum & Prostate 1.5 * * *
relationship between
health,sexual and
reproductive health Rep 1 Beh 1
BEHAVIOURAL Introducing the
SCIENCES concrpt of
1
relationship * - *
between
health,sexual and
reproductive health
Rep 1 Beh 2
Clarifying the components BEHAVIOURAL Clarifying the 1
of sexual and reproductive SCIENCES components * - *
individuals ofsexual and
reproductive
Rep 1 Ane 1
individuals
Explain development of EMBRYOLOGY Development of 1 * - *
male reproductive system male reproductive
system
Rep 1 Ang 9
ANATOMY Development of
external genitilia
Male external
1.5 * - *
genital organ Male
urethra
Discuss the congenital, Rep 1 Pth 1
genetic, and developmental Congenital
anomalies of male genital Anomalies of male
tract in relation to PATHOLOGY genital tract, 1 * - *
morbidity and clinical Testicular atrophy,
implications Epididymoorchitis
Rep 1 Phy 1
PHYSIOLOGY Gametogenic
function of testis
Explain spermatogenesis ( spermatogenesis ) 1 * - *
and relate the mechanism Endocrine functions
of spermatogenesis and ( secretions of
hormonal regulation. testosterone )
427
Rep 1 Phy 2
PHYSIOLOGY Functions of
testosterone,
Applied physiology
1 * - *
(hyper & hypo
gonadism)
Identify the microscopic HISTOLOGY Rep 1 Anh 2
features of the parts of Prostate, Seminal 1 1.5 * - *
male reproductive system. Vesicle,
Discuss the importance of GROSS Bulbourethral
Rep 1 Ang10
descend of testes and glands
ANATOMY Prostate, Ductus
enlargement of prostate deferens, Seminal
1.5 * - *
vesicle, Applied
Describe the enlargement
Rep 1 Pth 2
etiopathogenesis, PATHOLOGY BPH,PSA
Prostatitis, BPH
morphology and diagnostic
features of prostatitis,
1 * - *
hyperplasia and prostatic
carcinoma
Relate the mechanism of Rep 1 Phy 3
ovulation including PHYSIOLOGY Function of ovary
hormonal regulation with Ovulation
1 * - *
its abnormalities.
Define empowerment and BEHAVIOURAL Rep 1 Beh 3
factors influencing the SCIENCES Define
empowerment of empowerment and 1 * - *
individuals factors influencing
the empowerment
Evaluate the local scenario BEHAVIOURAL of
Repindividuals
1 Beh 4
of Reproductive health SCIENCES Evaluate the local
scenario of 1 * - *
Reproductive
health
Relate the mechanism of Rep 1 Phy 3
ovulation including PHYSIOLOGY Function of ovary:
hormonal regulation with Ovulation 1 * - *
its abnormalities
Describe synthesis, Rep 1 Bio 1
regulation and functions BIOCHEMISTRY Synthesis of steroid
of hormones of female hormones
1.5 * - *
reproductive system Rep 1 Bio 2
Synthesis,
regulation and
functions of
1 * - *
Estrogen
Rep 1 Bio 3
Synthesis, 1
regulation and * - *
functions of
Progesterone
428
BIOCHEMISTRY Rep 1 Bio 4
Synthesis,
Describe the mechanism of regulation and
action, clinical uses, functions of
1 * - *
adverse effects and Prolactin
contraindications of PHARMACOLO Rep 1 Pha 1
androgens and their GY Androgens & Anti-
antagonists Androgerns 1 * - *
Describe the mechanism of PHARMACOLO Rep 1 Pha 2

actions, clinical uses, GY Estrogens & Anti-
adverse effects and estrogens
contraindications of 1 * - *
estrogen and anti-
estrogens
Describe the development EMBRYOLOGY Rep 1 Ane 2
of parts Development of
of female parts of female
1 * - *
reproductive system
reproductive
Discuss major blood vessels ANATOMY system
Rep 1 Ang 11
and nervous plexus found Internal iliac artery 1 * * *
in pelvic cavity and their and its branches
clinical importance ANATOMY Rep 1 Ang 12
Nerves of Pelvis & 1 * * *
Perineum , sacral
Plexus
ANATOMY Rep 1 Ang 13
Venous &Lymphatic 1.5 * * *
drainage of pelvic
cavity
GROSS Rep 1 Ang 14
Identify the microscopic ANATOMY Female genital 1.5 * * *
features of the parts of tract: Fallopian
female reproductive tube, ovary
system. HISTOLOGY Rep 1 Anh 3 Ovary,
Fallopian tube
1 1.5 * * *
GROSS Rep 1 Ang 15
ANATOMY Uterus, Cervix, 1.5 * * *
Vagina
HISTOLOGY Rep 1 Anh 4uterus,
cervix, vagina 1 1.5 * * *
Discuss the congenital, ANATOMY Rep 1 Ang 16
genetic, and developmental Female External 1.5 * - *
anomalies of female genital Genitilia& female
tract in relation to PATHOLOGY urethra
Rep 1 Pth 4
morbidity and clinical Congenital
implications. Anomalies of 1 * - *
Female Genital
Tract & PIDs
429
GYNAE & OBS Rep 1 Obg
1Common
Developmental 1
Anomalies of * - *
female
reproductive
system
Discuss pathology of PATHOLOGY Rep 1 Pth 5
dysfunctional uterine Dysfunctional
bleeding and discuss uterine bleeding,
Endometrial 1 * - *
endometrial hyperplasia in
Hyperplasia
relation to hormonal
imbalances
Describe the biochemical BIOCHEMISTRY Rep 1 Bio 5
changes during menarche Describe the 1.5
biochemical
* - *
GYNAE & OBS changes
Rep 1 during
menarche
Obg2Menstrual
Disorders
1 * - *
Describe Non-neoplastic & PATHOLOGY Rep 1 Pth 7
functional cysts of ovary Non-neoplastic & 1
functional cysts of * - *
Describe normal sexual BEHAVIORAL ovary
Rep 1 Beh 5 normal
response cycle in male & SCIENCES sexual response
female cycle in male & 1 * - *
female
Rep 1 Ang 17
Describe structure ANATOMY Structure of 1 * * *
&function of placenta placenta
PHYSIOLOGY Rep 1 Phy 4
Function of
1 * - *
Discuss Culture Bound BEHAVIORAL placenta
Rep 1 Beh 6 Culture
Syndromes (Dhat SCIENCES Bound Syndromes 1 * - *
Syndrome) (Dhat Syndrome)
Rep 1 Phy 5
Discuss pregnancy and PHYSIOLOGY Physiological
parturition. changes during
1 * - *
pregnancy
Rep 1 Bio 6
BIOCHEMISTRY Pregnancy Test
(measurement of
beta HCG levels by
different methods) 1.5 * * *
Practical: Urine
Pregnancy Test for
confirmation of
pregnancy
Rep 1 Obg 3
GYNAE & OBS Normal labour , * - *
430
Parturition (stages ,
mechanism , role of
hormones)
Rep 1 Bio 6 Identify
Identify the metabolic BIOCHEMISTRY the metabolic
needs of women during needs of women 1 * - *
pregnancy &lactation during pregnancy
&lactation
Recognize Behavioral Rep 1 Obg 4
aspects of change in GYNAECOLOGY HRT
reproductive life & OBSTETRICS
(physiological changes at 1 * - *
puberty in both male and
female(secondary Sex
Characteristics)
Relate role of hormones for Rep 1 Phy 6
mammary glands PHYSIOLOGY Composition of
development and milk breast milk &
1.5 * - *
secretion. lactation
COMMUNITY Rep 1 Com1
MEDICINE Breast milk benefits 1 * - *
Identify and discuss the Rep 1 Pth 9
disorders of early Disorders of early
pregnancy (abortion, PATHOLOGY pregnancy
ectopic pregnancy and
1 * - *
gestational trophoblastic
diseases.
Identify and discuss the Rep 1 Pth 10
disorders of late pregnancy. PATHOLOGY Disorders of late 1
Discuss contraception & its pregnancy * - *
application & compare diff.
contraceptives
PHARMACOLO Rep 1 Pha 3 1 * - *
GY Compare diff.
contraceptives
Evaluate Myths & BEHAVIORAL Rep 1 Beh 7 1 * - *
misconception about SCIENCES Evaluate Myths &
reproductive problems in misconception
local socio-cultural set up about reproductive
problems in local
socio-cultural set
up
431
REPRODUCTION MODULE
TIME TABLE
FIRST WEEK
Days 8:30- 10:00 10:30- 11:30 11:30-12:30 1:30-3:00

Anatomy Lecture Anatomy Demo : 4 Batches
BEHAVIORAL SCIENCES Anatomy Lecture Perineum: Bony Pelvis,
Introducing the concept of (inlet and outlet) Difference
Sacrum and coccyx divisions (Urogenital
relationship between health, between male and female pelvis
Joints of pelvic cavity Diaphragm)of
1 sexual and reproductive health. Types of bony pelvis
Name of Faculty perineum and
Name of Faculty &Cephalopelvic disproportion
Venue Perineal body
Venue A+B= Name of Faculty Venue
Name of Faculty C+D+E= Name of Faculty
Venue
Venue
A-Biochemistry Tutorial:
Synthesis of steroid hormones
BEHAVIORAL
B-Histology: Practical Anatomy SCIENCES Anatomy Demo:4 Batches
Testes and ducts System Male internal genital Clarifying the Pelvic walls,
Name of Faculty Venue organ: Gross Anatomy components of sexual Pelvic Floor and pelvic fascia
of Testes, epididymis, and reproductive Division of pelvis
2
scrotum
C1-SKILL LAB:Examination of individuals A+B= Name of Faculty Venue
Name of Faculty
rectum and prostate Name of Faculty C+D+E= Name of Faculty
Venue
C2: SELF STUDY Venue Venue
D= SELF STUDY
E-Self-study
3 INDEPENDENCE DAY
Anatomy Anatomy Demo:

1. B Anatomy Anal Region Anal-Canal
Development of male
4 2. C= Histology: Testes
reproductive system A+B= Name of Faculty Venue
3. D Name of Faculty
Name of Faculty C+D+E= Name of Faculty
4. E Venue
Venue Venue
5. A
10:00 to 11:00 11:00 to 12:00
1. C Pathology
2. D=
Physiology:
Gametogenic function of Congenital Anomalies
3. E of Male Genital Tract,
testis (spermatogenesis )
5 4. A Testicular Atrophy and
Endocrine functions
5. B Epididymo-orchitis
(secretions of testosterone )
Name of Faculty Venue Name of Faculty
Venue
Physiology
Functions of
1. D testosterone, Anatomy
6 2. E= Applied physiology Ischiorectal Fosse
3. A (hyper and hypo- Name of Faculty SELF - STUDY
4. B gonadism Venue
5. C
Name of Faculty
Venue
432
Reproduction Module 1, Semester IV
Time Table - Week 2
Days 8:30- 10:00 10:30- 11:30 11:30-12:30 1:30-3:00

BEHAVIOUR SCIENCES Anatomy Demo:
Define empowerment Gross: Prostate, Ductusdeferens,
1.E and factors influencing Histology Seminal Vesicle, Applied
2.A=3.B the empowerment of Prostate, Seminal Vesicle, enlargement BPH, PSA
1 4.C individuals. Bulbourethral glands
A+B= Name of Faculty Venue
5.D Name of Faculty Name of Faculty Venue
C+D= Name of Faculty Venue
Venue E= Name of Faculty Venue
A=CBL
B=Biochemistry Tutorial:
Describe the biochemical changes
during menarcheName of
Faculty Venue
BEHAVIOUR Anatomy Demo:
SCIENCES Male external genital organs
C2=Examination of rectum and Evaluate the local Pharmacology Male urethra+ Development
prostate SKILL LAB Scenario of Androgens and Anti Androgens external genitalia
2 C1=SELF-STUDY Reproductive Health A+B= Name of Faculty Venue
D=Histology Practical: Name of Faculty C+D= Name of Faculty Venue
Prostate, Seminal Vesicle Venue E= Name of Faculty Venue
Bulbourethral glands
E=SELF-STUDY
Anatomy Gross:Demo:
1. B Female genital tract: ovary, fallopian
2. C tube
Pathology
3 3. D A+E= Name of Faculty Venue
SELF STUDY Prostatitis & BPH
4. E= B+C+D= Name of Faculty Venue
5. A
Anatomy Demo:
1. C Histology: Uterus, cervix, Vagina
2. D= Ovary, fallopian tube A+E= DR SABAHAT NLH=2 Physiology
3. E Name of Faculty Function of ovary: Ovulation
4 Name of Faculty Venue
4. A= Venue Name of Faculty Venue
5. B
B+C+D= Name of Faculty Venue
Biochemistry
1. D Histology: Synthesis, regulation and functions of
2. E= Uterus, cervix, Vagina hormones of female
5 3. A Name of Faculty reproductivesystemEstrogen
4. B = Venue Name of Faculty Venue
5. C
Biochemistry
1. E Pharmacology
Synthesis, regulation and functions of
2. A= Estrogens and Anti
hormones of female reproductive
6 3. B estrogens
system Progesterone
4. C= Name of Faculty SELF STUDY
5. D
Venue
433
REPRODUCTION MODULE 1, SEMESTER IV
TIME TABLE - WEEK 3
Days 8:30- 10:00 10:30- 11:30 11:30-12:30 1:30-3:00

A=Biochemistry tutorial:
Hormones of infertility
Embryology Pathology
1 B=Histology practical: ovary, Development of parts of Describe Non neoplastic and
SELF-
fallopian Name of Faculty Venue female reproductive system STUDY
functional cysts of Ovary&
Name of Faculty Venue PCOS
C=CBL
D+E= SELF STUDY
BEHAVIORAL
Anatomy SCIENCES
Nerves of pelvis and perineum Describe normal Pharmacology
Anatomy
Contraceptives Internal iliac artery and its branches
2 +sacral plexus sexual response
Name of Faculty Venue A+B+C= Name of Faculty Venue
Name of Faculty Venue cycle in male and
female
Name of Faculty D+E= Name of Faculty Venue
Venue
B= Name of Faculty Venue Pathology Anatomy Demo:

C= Name of Faculty Venue Congenital Anomalies of Female External genitalia
3 Female Genital Tract & PIDs
SELF- And female urethra
STUDY A+B+C=Name of Faculty Venue
D Name of Faculty Venue
E+A D+E= Name of Faculty Venue
C= Name of Faculty Venue Community medicine

Pathology
Discuss contraception and its
Dysfunctional Uterine Bleeding SELF-
D= Name of Faculty Venue application according to the
4 & Endometrial Hyperplasia STUDY
needs of Pakistan
E Name of Faculty Venue
A+B
D= Name of Faculty Venue Clinical Faculty
Common Developmental Anomalies of
5 E= Name of Faculty Venue female reproductive system
A Name of Faculty Venue
B+C
E= Name of Faculty Venue

BEHAVIORAL SCIENCES
Sexual and reproductive
6 A= Name of Faculty Venue ELSEVIER OLYMPIAD AT DMC
dysfunction and its management
B (ATTENDANCE COMPULSORY)
C+D
434
`TIME TABLE FOR REPRODUCTION MODULE 1
SEMESTER IV WEEK 4
Days 8:30- 10:00 10:30- 11:30 11:30-12:30 1:30-3:00
Anatomy
Physiology Venous and lymphatic drainage
Clinical Faculty Anatomy of Pelvic cavity
Function of placenta
Menstrual Disorders Structure of Placenta A+B= Name of Faculty Venue
Name of Faculty
1 Name of Faculty Venue Name of Faculty Venue C+D= Name of Faculty Venue
Venue
E=Name of Faculty Venue
A=Physiology Tutorial: Composition &

importance of breast Milk Name of
Faculty Venue
B=CBL Physiology
C=Histology practical: Physiological changes Pathology
2 Uterus, cervix, Vagina during pregnancy Disorders of early pregnancy
SELF STUDY Name of Faculty Name of Faculty Venue
Venue
D=Biochemistry Practical: Pregnancy Test
(measurement of beta HCG levels by different
methods) Urine Pregnancy Test for confirmation of
pregnancy Name of Faculty Venue
E=Self-study
Biochemistry
Synthesis, regulation
B= Physiology and functions of
Pathology
C Mammary gland and hormones of female
Disorders of late pregnancy
3 D lactation reproductivesystempr
E Name of Faculty Venue olactin
A Name of Faculty
Venue
Biochemistry Clinical Faculty

C Clinical Faculty
Identify the metabolic Normal Labor,Parturition
D HRT
4 needs of women during (stages, mechanism and role
E
pregnancy and lactation Name of Faculty of hormones)
A Venue
Name of Faculty Venue Name of Faculty Venue
B
Anatomy-REVISIT
Perineum: Anatomy-REVISIT
D=
Peritoneum with
E divisions (Urogenital
relation to pelvis
5 A Diaphragm)of perineum
andPerineal body Name of Faculty
B
Venue
C Name of Faculty Venue
E Embryology-revisit
Community medicine
A Development of male and femalereproductive
6 Breast milk: Benefits
B system +congenital anomalies
C Name of Faculty Venue
D
435
LEARNING OBJECTIVES
GROSS ANATOMY
REP1 Ang1 BONY PELVIS SACRUM AND COCCYXJOINTS OF PELVIS
Define bony pelvis,

Describe surfaces of sacrum.
Explain articulation.
Identify muscles associated with sacrum.
Differentiate between male and female sacrum.
Enlist various types of joints of pelvis.
Explaintype , articulations , ligaments relation of joints.
Enlist factors providing stability to joint.
Describe blood supply , nerve supply & movements of joint.
REP 1 Ang 2 THE BONY PELVIS (INLET & OUTLET DIFFERENCE BETWEEN MALE & FEMALE PELVIS
Differentiate the greater & lesser pelvis.

Describe the superior & inferior circumference and their boundaries.
Describe the anatomical position of pelvis.
Differentiate the shapes of female pelvis regarding childbirth.
Differentiate between male & female pelvis.
REP1Ang3 PELVIC FLOOR
Describe the anatomy of the pelvic walls.

Discuss the muscles of pelvic floor
Develop an understanding of blood supply, nerve supply, lymphatic drainage of muscles.
Describe actions of pelvic diaphragm.
REP 1 Ang 4 DIVISION OF PERINEUM AND CUTANEOUS NERVES. PERINEAL BODY.
Identify borders and relationsof the perineum.

Describe divisions of the perineum.
436
Explain cutaneous nerves of the perineum.
Define perineal body.
REP 1 Ang 5 ANAL CANAL
Explain the gross anatomy of Anal Canal

Identify the relations of the anal canal with the surrounding structures.
Describe the blood supply, venous and lymphatic drainage of anal canal.
Explain innervations of anal canal.
REP 1 Ang 6 MALE INTERNAL GENITAL ORGAN - TESTES AND EPIDYDIMIS
Describe the coverings of testis.

Recognize the internal features of testis.
Explain the significance of pampiniform plexus.
Justify the location of testis outside the body
Defend the role of testicular maturation in epididymis
Integrate the knowledge of descent of testis to its vessels, lymphatics and nerves.
Recall the different clinical conditions associated with testis.
REP 1 Ang 7 OVERVIEW OF PELVIC ORGANSSIGMOID COLON, RECTUM, URINARY BLADDER
Describe pelvic organs.

Describe sigmoid colon.
Describe rectum.
Explain structure of urinary bladder.
Explain relations of these pelvic organs.
Describe blood supply and innervation of these pelvic organs
REP 1 Ang 8 THE ISCHIORECTAL FOSSA
Explain the details of ischiorectal fossa.

Identify the boundaries and recessess of ischiorectal fossa
Describe the contents of ischiorectal fossa.
REP1 Ang 9 MALE EXTERNAL GENITALIA MALE URETHRA
Describe gross anatomy of male external genitalia.
437
Explain their arterial, venous drainage & nerve supply.
Explain anatomy of male urethra, its arterial, venous drainage & nerve supply.
Discuss the normal human embryology of human genital tract.
Differentiate between male & female sex organs.
Discuss the mal development of external genitalia.
REP 1 Ang10 MALE INTERNAL GENITAL ORGAN - DUCTUS DEFERENS, SEMINAL VESICLES &
PROSTATE
Describe the gross features of male internal organs: Epididymis, Ductus Deferens,
Seminal Vesicles & Prostate
Explain their blood supply , nerve supply & lymphatic drainage.
Discuss clinical correlation: Benign Prostatic Hyperplasia and clinical significance of High
PSA levels.
REP1 Ang 11 INTERNAL ILIAC ARTERY
Describe the course of the common iliac artery.
Identify divisions of internal iliac by their relationships to pelvic organs or wall
structures.
REP1Ang12 NERVES OF PELVIS AND PERINEUM + SACRAL PLEXUS
Identify pelvic nerves.

Describe Sacral plexus.
Identify coccygeal plexus.
Describe pelvic hypogastric plexus.
REP 1 Ang 13 VENOUS AND LYMPHATIC DRAINAGE OF PELVIS
Describe main veins of the pelvis and their tributaries.

Identify area of drainage of these veins.
Describe different groups of lymph nodes.
Explain afferent and efferent pathways of different groups.
Explainrole of lymphatics and common route of spread of malignancies of pelvis.
REP1 Ang 14 OVARIES AND FALLOPIAN TUBE

Identify ovaries and fallopian tubes.
Describe the parts of ovaries and falloprian tubes.
Identify the ligaments of ovaries
Enumerate the clinical correlates of ovaries and uterine tubes.
438
REP 1 Ang 15 UTERUS, CERVIX AND VAGINA
Explain the details of uterus, cervix and vagina.

Enumerate the parts of uterus, ligaments of uterus and relations of uterus.
Identify the clinical correlates of uterus, cervix and vagina.
REP 1 Ang 16 FEMALE EXTERNAL GENITALIA AND FEMALE URETHRA
Enlist the names and anatomical location of female external genitalia.

Explain function, arterial supply, venous drainage and nerve supply of female
external genitalia.
Discuss clinical importance of female external genitalia.
Explain course & relations of female urethra.
Describe arterial supply, venous drainage and nerve supply of female urethra.
Discuss clinical importance of female urethra.
REP 1 Ang17 STRUCTURE OF PLACENTA
Describe placental hormone production and identify the cellular components of the
placenta that produce the hormones.

Explain the placental barrier.
Describe a chorionic villus.

Explain the formation and structure of the mature placenta.

Discuss the placental barrier and maternal and fetal blood flow in the placenta.

HISTOLOGY
REP 1 Anh 1 HISTOLOGY OF TESTIS AND DUCT SYSTEM
439
Enlist the male reproductive organs.
Describe the histological anatomy of testis and duct system.
Differentiate these two structure under microscope.
REP 1 Anh 2 HISTOLOGY OF SEMINAL VESICLES, PROSTATE & BULBOURETHRAL GLANDS

Explain the histology of Seminal Vesicle.
Explain the histology of Prostate gland.
Describe the histology of Bulbourethral glands of Cowper.
Enlist the secretions of the above mentioned accessory exocrine glands.
Describe the composition of Semen.
REP 1 Anh 3 HISTOLOGY OF OVARY AND FALLOPIANTUBES
Describe components of the female reproductive system.

Explain the general organization of the ovaries.
Identify ovary and ovarian follicles under microscope.
Identify layers and cells of fallopian tubes under microscope.
REP 1 Anh 4 HISTOLOGY OF UTERUS, CERVIX AND VAGINA
Discuss uterus histology.

Identify layers of uterus histologically.
Identify phases of menstruation of uterus.
Identify cervix histologically.
Identify both uterus and vagina histologically.
EMBRYOLOGY
REP 1 Ane 1 DEVELOPMENT OF MALE REPRODUCTIVE SYSTEM
Discuss the development of parts of male reproductive system.

Explain the applied anatomy of development of male reproductive system.
REP 1 Ane 2 DEVELOPMENT OF PARTS OF FEMALE REPRODUCTIVE SYSTEM
Discuss the precursor and migration of primordial germ cell.
440
Define the location and division genital ridge .
Differentiate development of male and female genital tract.
Describe the development of female genital ducts.
Discuss the development and differentiation of Paramesonephric ducts and
development uterus and vagina.
PHYSIOLOGY
REP 1 Phy 1GAMETOGENIC FUNCTION OF TESTIS - SPERMATOGENESIS - ENDOCRINE

FUNCTIONS
Describe the process of spermeogenesis.

Identify the different parts of sperm.
Enumerate the different parts of male reproductive system.
Explain the structure of testis.
Define the structure of semineferrous tubules.
Correlate the harmonal control with the development process.
Illustrate the histologic features.
REP 1 Phy 2 FUNCTIONS OF TESTESTERONE, APPLIED PHYSIOLOGY (HYPER & HYPOGONADISM)
Describe Function of testeterone.

Define Hypogonadism.
DefineHypergonadism.
REP 1 Phy 3 FUNCTIONS OF OVARIES
Discuss reproductive physiology.

Describe functions of ovaries
Discuss oogenesis & Sexual Cycle.
Describe the changes in ovarian follicles in relation to oogenesis.
Describe the hormonal event that regulate the ovarian cycle.
Distinguish between a primordial, primary and secondary follicle.
Describe the effects of FSH & LH on the ovary.
Describe the effects of estrogen & progesterone on uterus, hypothalamus & anterior
pituitary.
441
REP 1 Phy 4 FUNCTIONS OF PLACENTA.
Explain the structure of placenta.

Discuss the function of placenta .
REP 1 Phy 5 MATERNAL CHANGES DURING PREGNANCY
Explain the different maternal changes during pregnancy.

Describe parturition and its stages.
REP 1 Phy 6 MAMMARY GLAND AND LACTATION
Explain anatomy of mammary gland,

Discuss physiology of mammary gland,
Describe lactation reflex,
Describe hormonal effect.
BIOCHEMISTRY
REP 1 Bio 1 STEROID HORMONE SYNTHESIS
Enlist types of steroid hormones.

Explain cholesterol is the common precursor molecule for the synthesis of steroid
hormones.
Describe the common metabolic pathway for synthesis of all steroid hormones.
Explain the synthesis of female sex hormones.
Describe synthesis of male sex hormones.
REP 1 Bio 2 SYNTHESIS, REGULATION& FUNCTIONS HORMONES OF FEMALE REPRODUCTIVE

SYSTEM
ESTROGEN
Enlist the hormones related to female reproductive system

Describe the structure, functions, and mechanism of action of Estrogen
Enlist the clinical conditions related to the hormones.
Enlist the lab investigations required for their diagnosis.
442
REP 1 Bio 3 SYNTHESIS, REGULATION& FUNCTION OF HORMONES OF FEMALE REPRODUCTIVE
SYSTEM
PROGESTERONE
Describe the synthesis of progesterone.

Enumerate the functions.
Interpret the mechanism of action and regulation.
Identify sites of secretion.
EP 1 Bio 4 SYNTHESIS, REGULATION& FUNCTION OF HORMONES OF FEMALE

REPRODUCTIVE SYSTEM
PROLACTIN
Describe synthesis of Prolactin.

Discuss the regulation of Polactin secretion.
Enlist functions of Prolactin.
Discuss its homeostasis.
REP 1 Bio 5 DESCRIBE THE BIOCHEMICAL CHANGES DURING MENARCHE
Define menarche.
List the changes associated with menarche.
Describe effects of hormones.
REP 1 Bio 6 IDENTIFY THE METABOLIC NEEDS OF WOMEN DURING PREGNANCY & LACTATION
Explain amount of energy required during pregnancy.

Enumerate the nutrients required in increased amount.
Describe the importance of iron & folic acid during pregnancy.
PATHOLOGY
1- REP 1 Pth 1 CONGENITAL ANOMALIES OF MALE GENITAL TRACT, TESTICULAR ATROPHY

AND EPIDIDYMO-ORCHITIS
Describe structure and function of reproductive system.
443
Explain mechanism of normal sexual determination and differentiation.
Discuss development of testes.
Differentiate male phenotype.
Describe congenital anomalies of descent of testis.
Describe hydrocele.
Explain dongenital inguinal hernia.
Enlist congenital anomalies of penis.
Discuss atrophy of testis.
Define epididymo-orchitis.
2- REP 1 Pth 2 PROSTATITIS & BPH
Explain the classification of prostatitis.

Define acute prostatitis.
Define chronic prostatitis.
Define abacterial prostatitis.
Describe anatomy of prostate.
Explain etiology of Benign Prostatic Hyperplasia.
Describe morphology of BPH.
Discus clinical features of BPH.
Discuss complication of BPH.
3- REP 1 Pth 3 CONGENITAL ANOMALIES OF FEMALE GENITAL TRACT &

PIDS
Enlist the congenital anomalies of uterus and vagina.

Enlist names of organisms which causeinfertility in females.
Identify the virus involved in the pathogenesis of cervical, vaginal, and vulvar cancers.
Define Pelvic inflammatory disease.
Enlist the causes of PID.
Describe the morphology of PID in fallopian tubes and ovaries.
Discuss the sequelaePID.
Discuss treatment for PID.
4- REP 1 Pth 4 DYSFUNCTIONAL UTERINE BLEEDING & ENDOMETRIAL

HYPERPLASIA
Define dysfunctional uterine bleeding.

Enlist the causes of DUB.
Define endometrial hyperplasia.
Describe the different morphological types of endometrial hyperplasia
444
5- REP 1 Pth 5 NON-NEOPLASTIC & FUNCTIONAL CYSTS OF OVARY
Describe etiology of non-neoplastic & functional cysts of ovary.

Discuss pathophysiology of non-neoplastic & functional cysts of ovary.
Establish diagnosis of non-neoplastic & functional cysts of ovary.
Discuss consequences of non-neoplastic & functional cysts of ovary.
6- REP 1 Pth 6 Disorders of early pregnancy
Define abortion.
Define molar pregnancy.
Enlist types of moles.
Define ectopic pregnancy.
7-REP 1 Pth 7Disorders of late pregnancy
Define twin placentas.

Discuss abnormalities of placental implantation.
Describe placental infections.
Define preeclampsia.
Define eclampsia.
Pharmacology
1- REP 1 Pha 1 Androgens and Anti Androgens
Explain the mode of action and side-effects of androgenhormones and anti- androgen
drugs.
Describe pharmacological actionof androgenhormones and anti- androgen drugs.
Enlist indications of androgenhormones and anti- androgen drugs.
Enlist contraindications of androgenhormones and anti- androgen drugs..
Explain drug Interactions of androgenhormones and anti- androgen drugs..
Enlist adverse effects.
Discuss management of anabolic steroids and androgen inhibitors.
2- REP 1 Pha 2 Estrogens and Anti estrogens
Describe the pharmacology of estrogen preparations and their use .

Describe the mechanism of action of Estrogens and Anti estrogens.
445
Enlist contraindicationsof Estrogens and Anti estrogens.
Explain drug Interactionsof Estrogens and Anti estrogens.
Enlist adverse effectsof Estrogens and Anti estrogens.
Discuss management of estrogens.
3- REP 1 Pha 3Contraceptives
Describe The Pharmacology Of Oral Contraceptive Drugs And Their Adverse Effects.
Enlist contraindicationsOf Oral Contraceptive Drugs.
Explain drug InteractionsOf Oral Contraceptive Drugs.
Enlist adverse effectsOf Oral Contraceptive Drugs.
Management Of Oral Contraceptives
BEHAVIOURAL SCIENCES
1- REP 1 Beh 1 PSYCHOSOCIAL ASPECT OF REPRODUCTIVE HEALTH

Introducing the concept of relationship between health, sexual and reproductive health

Clarifying the components of sexual and reproductive individuals
Define empowerment and factors influencing the empowerment of individuals .
4- REP 1 Beh 5 SOCIO-CULTURAL ASPECTS OF SEXUAL DYSFUNCTION
Describe normal sexual response cycle in male and female
5- REP 1 Beh 6 SOCIO-CULTURAL ASPECTS OF SEXUAL DYSFUNCTION
Sexual and reproductive dysfunction and its management
446
COMMUNITY MEDICINE
1- REP 1 Com1BREAST MILK: BENEFITS
Describe anatomy and Physiology of Lactation.

Enlist Types and Composition of Human Breast Milk.
Define Colostrum.
Enlist Benefits of Breastfeeding babies.
EnlistcContraindication to Breastfeeding .
2- REP 1 Com2CONTRACEPTION AND ITS APPLICATION ACCORDING TO THE NEEDS OF

PAKISTAN
Discuss contraception and its application according to the needs of Pakistan

Enlist Different methods of contraception.
Describe Classification of contraceptives.
Explain Effectiveness of contraceptive methods and failure rates.
Describe Mode of action of different contraceptive methods.
Enlist Contra indications of different contraceptive methods.
GYNAECOLOGY& OBSTETRICS
1- REP 1 Obg1 COMMON DEVELOPMENTAL ANOMALIES OF FEMALE
REPRODUCTIVE SYSTEM
Describe Structure and function of female genital tract.

Describe The mechanism of normal sexual determination and differentiation.
Explain Abnormal sex chromosome complexes.
Sexual determination.
Enlist Anomalies of female genital tract.
REP 1 Obg2 MENSTRUAL DISORDERS
Recall physiology of menstruation.

Describe terminologies & causes of AUB.
Discuss patho-physiology of DUB, esp role of eicosanoids.
Discuss types, causes, diagnosis of DUB.
447
REP 1 Obg3 NORMAL LABOR, PARTURITION (STAGES, MECHANISM AND ROLE
OF HORMONES)
Define Normal Labor.

Exlplain (stages of Normal Labor.
Describe mechanism of Normal Labor.
Describe role of hormones in normal labour.
REP 1 Obg 4 Hormone Replacement Therapy (HRT)
Describe Pathophysiology of menopause.

Describe Mechanism of menopause.
Explain Hormone Replacement Therapy.
Enlist Indications & Contraindications of HRT.
Reproductive Module:
I. EXAMINATION OF BREAST
INTRODUCTION / RATIONALE:
The clinical breast examination (CBE) can be used either for screening (to detect breast cancer in
asymptomatic women) or for diagnosis (to evaluate women who present with breast complaints).
Students often avoid examination of the breasts during routine physical exam because of
shyness. It should be an essential part of routine physical examination for early detection of
breast disease.
At the end of this session students should be able to:
1. Demonstrate the proper technique of clinical breast examination.
2. Demonstrate the examination of axillary and supraclavicular lymph nodes.
3. Identify the findings in following abnormalities.
a. Fibro adenoma
b. Carcinoma
448
CASE BASED LEARNING
REP 1 CBL
Describe the anatomy of male genitalia and its anamolies.

Describe the secretion and regulation of testosterone and gonadotrophins.
Describe the normal and abnormal semen parameters.
Identify the causes of male factor infertility.
Know the importance of clinical examination and investigation of male in infertile
couple.
REP I CBL2 PCOs
Define polycystic ovarian disease

Enlists the common cause of chronic anovulatoryamenorrhoea
449
TOTAL
WEEKS/HOURS 1st 2nd 3rd 4th Including (pract)
*** ROUND OFF
ANATOMY 12 10.5 7.5 4 34 39.54 40
BIOCHEMISTRY 1.5 3.5 1.5 3.5 10 11.63 12
PHYSIOLOGY 2 1.5 - 4.5 8 9.31 10
PATHOLOGY - 1.5 4.5 3 9 10.47 11
PHARMA - 2 1 - 3 3.48 3
BEHAVIORAL
2 2 2 - 6 6.98 7
SCIENCES
COMMUNITY
- - 1.5 1.5 3 3.48 3
MEDICINE
GYNECOLOGY - - 1.5 4 5.5 6.39 6
SKILL LAB 1.5 1.5 - - 3 3.48 3
Total 2 for SBL - 1.5 1.5 1.5 4.5 5.23 5
TOTAL 1 19 24 21 22 86 100 100
450
CREDIT HOURS
SEMESTER IV
REPRODUCTION-1 MODULE
Paper-III 3
REPRODUCTION 1
Paper-IV-C 1.5
451
REPRODUCTION-1 MODULE
(SEMESTER-IV)
SUMMATIVE ASSESMENT
THEORY

SEMESTER
ATP 25
EXAM
PAPER-III One best Questions 80%

20
based on CBL
Total 100
MODULE EXAM
EMQs 10
ATP 20 20%
MODULE PAPER
One best Questions
20
based on CBL
Total 100
STRUCTURED VIVA

SUMMATIV
ASSESME
SEMESTE
R EXAM
See Semester
NT

E
Assessment Plan
ASSESMENT TOOLS
Structured Feedback
Facilitator
NOTE: Paper I & IV-A of Semester 4 Examination are Based on GIT & Liver Module.
Paper III & IV-C of Semester 4 Examination are Based on Reproduction Module.
452
CREDIT
HOURS
GIT & Liver Module

80 Marks
(Semester Theory)
100
I GIT & Liver Module Marks 6
20 Marks
(Module Exam)
Renal & EXC-1 Module

40 Marks
(Semester Theory)
50
II Renal & EXC-1 Module Marks 3
10 Marks
(Module Exam)
Reproductive Sys Module

a 40 Marks
III Reproductive Sys Module Marks 3
b 10 Marks
(Module Exam)
GIT & Liver-1 Module

a
(Viva)
50 Marks 3
Renal & EXC-1 Module 100
IV b
(Viva)
25 Marks
Marks 1.5
Reproductive Sys Module
C
(Viva)
25 Marks 1.5
Semester-1 Total Credit Hours 18
453
454
SPIRAL -2
Clinical Sciences
455
SEMESTER -5
Infectious Diseases Module 4 Weeks 4.5 Credit Hours
Hematology -II Module 4 Weeks 4.5 Credit Hours
Respiration II Module 4 Weeks 4.5 Credit Hours
CardiovascularII Module 4 Weeks 4.5 Credit Hours
456
INFECTIOUS DISEASES MODULE
IDD 1
SEMESTER:-V
THIRDYEAR M.B.,B.S
457
Spiral Sem. Modules

II

4 Week
wks
Second th
Half of the class will cover Ophthalmology in first 3 weeks of 7 Semester and the other half will cover ENT
Spiral th
modules during this period. In the first 3 weeks of 8 semester the module will rives
Trauma, 6 week
3 week 8 Weeks
/ Burns 2 wk
2 Weeks
th
th
Emergency, Intensive care) (Inpatient, Ambulatory, Emergency, Intensive care
In Medicine, Pediatrics, Cardiology and Neurology units and Operation Theatres)
PARALLEL THEMES:
458
MODULE COMMITTEE
Dr. Abu Talib, Professor of Medicine, (Focal Person) DUHS
Dr. Siraj-us Salekeen, Assistant Professor of Medicine, DUHS
Dr. Piyar Ali, Assistant Professor of Medicine, DUHS
Dr. TanveerAlam, Assistant Professor of Medicine, DUHS
Dr. Ayesha Mehnaz, Professor of Pediatrics, DUHS
Dr. Yasmeen Taj, Associate Professor of Pathology, DUHS
Dr. Aijaz Qureshi, Associate Professor of Physiology, DUHS
Dr. Khalida Perveen, Professor of Anatomy, DUHS
Capt. Dr. FarhatMirza, Professor of Forensic Medicine, DMC, DUHS

Dr. NighatNisar, Professor of Community Medicine, DMC, DUHS
Dr. RazaurRehman, Professor of Psychiatry, CHK, DUHS
Documented by:
Dr.Tanzeela Khan, Department of Anatomy, Dow Medical College, DUHS
Coordinated by:
Dr.Tanzeela Khan, Department of Anatomy, Dow Medical College, DUHS
Reviewed by:
Module Committee
459
RATIONALE
Infectious diseases are the most common problems of our community. In the under developed
countries, like Pakistan, infectious diseases along with malnutrition are the commonest causes
of mortality. Most of the diseases are identifiable and curable if recognized early. It is
important for medical graduates to have sound understanding of microbiology of the
organisms and the diseases that they cause. Students should also understand the rationale of
the investigations to diagnose these diseases. They should also know the pharmacology of the
various drugs used to treat infectious disease and the rationale to treat the common diseases.
TERMINAL OBJECTIVES
Medical student, after completion of this module, should be able to:
Describe pathogenesis & clinical presentations of common bacterial, viral, fungal & microbial
infections.
Recognize the clinical presentation of common infectious diseases in community.
Take history & formulate appropriate plan of investigations for attaining differential diagnosis
Analyze findings of history, examinations & investigations for diagnosis.
Practice basic principles of management of infectious diseases.
Recognize preventive measures & prognosis for counseling the patients.
Be Aware of the prognosis and be able to counsel their patients accordingly.
460
LEARNING OBJECTIVES OF MODULE
Practical / spotting
DIGITAL LIBRARY
BCQs, SEQs EMQS

SELF STUDY
TUTORIALS
PRACTICAL
LECTURES
SKILL LAB
LIBRARY
SBL
viva
TOPIC/CONTENT
FACULTY
OBJECTIVES
PATHOLOGY Idd 1Pth 1 1.5

Acute and chronic
* - *
inflammation
Revisit pathophysiology
and pharmacology of
PHARMACOLOGY Idd 1Pha 1 1
common infectious
disorder. Drug Used for relevant
* - *
infection disease and
relevant microbiology
(Antimicrobials)
Idd 1 Com 1 1
COMMUNITY Introduction of module
* * -
MEDICINE Epidemiology related to
infectious diseases
Take detailed history, 1

Take detailed history, CLINICAL general physical - * *
general physical POSTING- examination and
examination and specific examination of
specific examination of REFERENCE BOOKS: patients with infectious
HUTCHISONS,
patients with infectious MCLEOD)
diseases
diseases (Temp, Pulse,
RR, rash, lymph nodes,
Respiratory, GIT, CVS
and CNS)
461
Idd 1Mic 1 1
Know the basic Common microorganisms
* *
pathophysiology of in relation to fever:
fever, microbiology and MICROBIOLOGY Typhoid ,T. B
pharmacology of Malaria
common infectious leishmaniasis with fever
diseases. Meningitis, Pneumonia
Staphylococci &
streptococci:- Pyogenic
Bactria
Infectious Mononucleosis
Influenza
Idd1 Pth 2 1
PATHOLOGY Epidemiology and
* * *
pathology of malaria
Understand the signs

Idd 1Pha2 1
& symptoms of
PHARMACOLOGY Anti-malarial Drugs
* * *
malaria, the relevant
diagnostic test and
their interpretation.
Identify the Idd 1 Med 1 1.5
complication of Clinical Features,
* * *
malaria (e.g. ARF, MEDICINE diagnosis, management
ARDS, sepsis and and complication of
cerebral malaria malaria
etc.). Give
appropriate
Idd 1 Com 2 1.5
treatment and
COMMUNITY Prevention of Typhoid,
* * *
should know the MEDICINE malaria and other all
various drugs of febrile illnesses
malaria.
Idd 1Pha 3 1
PHARMACOLOGY Drug used for Typhoid
* * *
Fever
MEDICINE Idd 1 Med 3 1

Clinical features diagnosis
* - *
and management and
complications
of Typhoid fever
Idd 1Pha 4 1
PHARMACOLOGY Antipyretics &
* * *
Anti-inflammatory drugs
462
PATHOLOGY Idd 1Pth3 1.5
Enlist relevant Pathology lab:
* * *
investigation their Bacteriology culture
interpretation of data techniques PCR, Serology
to reach the diagnosis. (L-1 P-1)
should be able to
counsel and treat the
patient and devise a
protocol of follow up
and explain the
outcome to the patient.
(Approach to the
patient with fever - MEDICINE Idd 1 Med 4 1.5
Demonstration) Approach to patient with
* * *
fever, types of fever
detailed history &
relevant clinical
examination.
PATHOLOGY Idd 1Pth 4 1

Define sepsis and SIRS Pathophysiology of
* * *
and enlist its causes, Sepsis/ SIRS
describe various
presentations and
Idd 1 Med 5 1
complications of sepsis. MEDICINE Approach to the patient
* * *
Approach to the patient
with sepsis
with sepsis
Clinical Features,
diagnosis management
and Complications of
Sepsis/ SIRS
PATHOLOGY Idd 1Pth 5 1 1.5

Define fever with rash Gram staining of
* * *
and know about Pyogenic samples to
different types of rash reveal the causative
and devise some agent
investigation and
interpret the result.
Idd 1 Med 6 1
They should be able to MEDICINE Approach to the patient
* - *
treat and counsel the
with mumps
patient and arrange for
follow up if necessary.
MICROBIOLOGY Idd 1Mic2 1
Approach to the patient
Micro Organisms causing
* * *
with sepsis
Fever with rash (Varicella
zoster, Measles,Rubella)
PEDIATRICS Idd 1Ped 1 1
Fever with rash and
* * *
IMNCI; EPI, MMR
463
MICROBIOLOGY Idd 1Mic3 1 1.5
Define diarrhea, types Diarrhea and dysentery:
* * *
of diarrhea (acute and Agents causing diarrhea
chronic). Bacterial, Parasitic and
Enumerate various viruses (1 AND 2)
causes of both. Able to
understand the basic
Idd 1 Med 7 1
pathophysiology MEDICINE Approach to patient with
* * *
causing diarrhea.
Infectious diarrhea and
(pathology)
dysentery.
Take history and
Diarrhea, Dysentery in
relevant examination in
Adults
patients with diarrhea,
utilize labs and its
PHARMACOLOGY Idd1Pha 5 1 1.5
interpretation and able
Anti-diarrheal and anti-
* * *
to use the drugs used in
diarrhea. microbial drugs
Define Dysentery,
various organisms Idd 1 Med 8 1 1.5
causing it and able to MEDICINE Approach to patient with
* * *
identify each on clinical acute & chronic
grounds, and can diarrhea.(1 Lec, CBL)
manage by appropriate
Idd 1Ped2 1
PEDIATRICS IMNCI: Assess and
* * *
Classification of the sick
child and management
with Diarrhea, dysentery
and worm infestation
drugs and measures to Idd 1 Com 3 1

prevent it. COMMUNITY Prevention of infectious
* * *
MEDICINE Diarrhea and worm
infestations
Idd 1Pth 6 1 1.5

PATHOLOGY Bacteriology culture
* *
techniques PCR, Serology
(P-1)/ Stool D/R
Idd 1Mic 4 1
Understand the life MICROBIOLOGY Worm infestation
* * *
cycle of
Echinococcusgranulosu
s causing Hydatid cyst
disease, its clinical PHARMACOLOGY Idd1Pha 6 1 1.5
features and Anti-Helminthic drugs
* * *
complications and
various drugs used to
treat this.
Idd 1 Med 9 1
MEDICINE Hydatid Disease
* * *
464
Idd1 Med 10 1
MEDICINE Leishmaniasis,
* * *
Cystisercosis
Idd1 Med 11 1
Define and describe MEDICINE Clinical features,
* * *
STDs (Sexually diagnosis, management
transmitted disease) and complications of
and to know about STDs
different STDs.
They should be able to PHARMACOLOGY Idd 1Pha 7 1 1.5
take relevant history Drug management of
* * *
and perform physical STDs
examination, enlist lab
investigation, to reach
the diagnosis they
should be able to
counsel and arrange
the follow up if MICROBIOLOGY 1
Idd 1Mic 5
necessary.
Micro-organisms causing
* * *
STDs
1
Define and describe MEDICINE Idd 1 Med 12
* * *
Rabies and its clinical Clinical/therapeutic
types. They should be approach to the patient
able to take relevant with Rabies.
history and perform
physical examination.
Enlist investigation and
interpret the data for
treatment and
diagnosis. He should be
able to counsel the
attendants and explain
the grave prognosis.
Idd 1Pha 8 1
Define and describe PHARMACOLOGY Drugs used for
* * *
leprosy and its types, management of Leprosy
should be able to take
relevant history and 1
perform physical MEDICINE Idd1 Med 13
* * *
examination.
Leprosy
They should be able to
plan treatment and
subsequent follow up.
They should be able to
counsel the patient and
attendant because of
prolonged course.
Take history of patient 1

with various viral MEDICINE Idd 1 Med 14
* * *
hemorrhagic fevers Approach to the patient
including dengue fever with VHF / Dengue their
465
and understand the diagnoses and treatment
severity of disease, its
clinical examination. 1
Suggest appropriate MICROBIOLOGY Idd 1Mic 6
* * *
Also counsel the VHF & Dengue
patient and their
relatives about the
course & prognosis of
diseases.
1
Take the history of PATHOLOGY Idd 1Pth 7
* * *
patients which are HIV structure and
suspected cases of HIV pathogenesis
(Inquire about sexual
&travel history etc.) 1 1.5
understand the various PATHOLOGY Idd 1Pth 8
* * *
types & stages of HIV.
List the specific lab tests
List the specific lab
of HIV to make proper
tests of HIV and make
diagnosis
proper diagnosis. Treat 1 1.5

the HIV Patient PHARMACOLOGY Idd 1Pha 9
* * *
according to the Drug management of HIV
current guideline and
do the proper
counseling. 1
MEDICINE Idd 1 Med 15
* * *
Clinical features,
diagnosis, management
and complications of HIV
466
TIME TABLE
FIRST WEEK
Days 8:30 to 9:30 9:30 to 10:30 10:30 to 1:00 01:30 to 3.00

Community
Forensic Medicine Medicine:
Introductory class:
Introduction of Pathology
Forensic Medicine &
module Medicine Acute & Chronic inflammation
1 Sciences, Various Branches
& their importance and Epidemiology History Taking (Part I & II)
utility in civilized society related to Name of Faculty
Venue
Name of Faculty infectious diseases
Venue
Microbiology-Common Medicine
Pharmacology Medicine
microorganisms in Approach to the patient with
2 Antimicrobials Physical
relation to fever Name of Faculty
fever , types of fever
Examination Name of Faculty
Venue Venue
Medicine
Pathology Surgery
PharmacologyAn Clinical Features, diagnosis,
Epidemiology and History Taking &
3 ti-malarial Drugs Examination management and complication
pathology of malaria Name of Faculty
Name of Faculty Name of Faculty of malaria
Venue Venue Name of Faculty
Venue
Venue
Clinical Faculty
Clinical features Paeds.
Pharmacology Community Medicine
diagnosis and History Taking
Drug used for Typhoid Prevention of Typhoid, malaria
4 management and & Physical
Fever and other all febrile illnesses
Name of Faculty
complications Examination Name of Faculty
Venue of Typhoid fever Name of Faculty Venue
Venue
Clinical
Pharmacology Gynae.
FacultyTetanus History Taking
antipyretics &
5 and Clostridial
Anti-inflammatory drugs & Examination
Name of Faculty Infections ALH Name of Faculty
Venue Name of Faculty Venue
Venue
Medicine
Forensic Medicine Clinical Faculty History Taking &
Legal Procedures Rabies Physical
6 Examination
SELF-STUDY
Venue Venue Name of Faculty
Venue
467
INFECTIOUS DISEASE MODULE
TIME TABLE SECOND WEEK 2

Theme: Infectious Diarrheal Disease and Worm Infestation
Days 8:30 to 9:30 9:30 to 10:30 10:30 to 1:00 01:30 to 3.00
SBL Gp A: 1-64
Lab: Bacteriology culture techniques
PCR, Serology (P-1)/ Stool D/R
Microbiology PATHO LAB Gp B (R.No:65-129)
Forensic Medicine
Diarrhea and dysentery: Agents Lab/Tutorial/Pharma: Typhoid fever
Thanotology
causing diarrhea Bacterial Parasitic Management PHARMA LAB Gp C
1 Ward posting
and viruses (Part 1) (R.No:130-194)
Name of Faculty
Venue
Name of Faculty 1)UG Skill Lab 2)Self Study
Venue
SKILL LABGp D: (R.No:195-260)
Forensic Medicine:
Name of Faculty
Venue Gp E: (R.No:261-331)
Microbiology
Diarrhea and dysentery: Pharmacology 1.B
Agents causing diarrhea Anti-diarrheal and anti microbial 2.C
2 Bacterial Parasitic and viruses drugs Ward posting 3.D
(Part 2) Name of Faculty 4.E
Name of Faculty Venue 5.A
Venue
Pediatrics
Clinical Faculty
IMNCI Lecture 1
Approach to patient with 1.C
Assess and Classification of the sick
Infectious diarrhea and 2.D
child and management with
3 dysentery. Ward posting 3.E
Diarrhea, dysentery and worm
Diarrhea, Dysentery in Adults 4.A
infestation:
Name of Faculty 5.B
Venue
Name of Faculty
Venue
1.D
Microbiology Pharmacology
2.E
Worm infestation Anti Helmintic drugs
4 Ward posting 3.A
4.B
Venue Venue
5.C
Clinical Faculty
Clinical Faculty Leishmaniasis, Cystisercosis
Hydatid Disease DR.PIYAR ALI
5 Ward posting
Venue Venue
Community Medicine: 1.E

Forensic Medicine
Prevention of infectious Diarrhea 2.A
Thanotology
6 and worm infestations Ward posting 3.B
Name of Faculty
Name of Faculty 4.C
Venue
Venue 5.D
468
INFECTIOUS DISEASE MODULE Week 3
Theme: Sepsis/ SIRS, Fever with rash, VHF/ Dengue
Days 8:30 to 9:30 9:30 to 10:30 10:30 01:30 to 3:00

to 1:00
Community Medicine:
1.E
Prevention of Pathology 2.A
infectious Diarrhea and Pathophysiology of Sepsis/ SIRS Ward
1 3.B
worm infestations Name of Faculty posting 4.C
5.D
Venue
SBL Gp A:MEDICAL WARDS.

Clinical Faculty
Clinical Features, Lab Gp B: PHARMA LAB
diagnosis Microbiology Ward Gp CPATHO LAB
2 management and VHF & Dengue posting Lab/Tutorial:Patho-diagnosis of
Complications of Name of Faculty
Venue pathogens on blood culture
Sepsis/ SIRS
Name of Faculty 1.UG Skill Lab 2.Self Study
Venue Gp D= SKILL LAB
Microbiology
Clinical Faculty Micro Organism for Fever with 1.B
VHF & Dengue rash:Varicellazoster,Measles, Ward 2.C
3
Name of Faculty Rubella posting 3.D
Venue Name of Faculty 4.A
Venue
Pediatrics
Clinical Faculty 1.C
Fever with rash and IMNCI Ward 2.D
4 Mumps
: EPI, MMR, posting 3.A
Name of Faculty
Venue Name of Faculty 4.B
Venue
Pharmacology
Clinical Faculty
Drug used for Ward
5 Leprosy,
Leprosy posting
Name of Faculty
Venue
1.D
Community Medicine: 2.A
Forensic Medicine
Prevention and control of VHF, Ward 3.B
Thanotology
6 dengue, and fever with rash 4.C
Name of Faculty posting
Venue
469
INFECTIOUS DISEASES MODULE SEMESTER V
TIME TABLE FOURTH WEEK (IV)
Theme: HIV- STD
10:30 to
Days 8:30 to 9:30 9:30 to 10:30 01:30 to 3:00
1:00
SBL Gp A: Medical Wards
Patho Lab Group B

Forensic Medicine Pathology
Sequele of death HIV structure and pathogenesis Ward Pharma Lab Group C
1
Name of Faculty Name of Faculty posting
Venue Venue Self StudyGroup D
Forensic Medicine Group E:
1.B
Pathology
Pharmacology 2.C
List the specific lab tests of HIV to
Drug management of HIV Ward 3.D
2 make proper diagnosis.
Name of Faculty posting 4.E
Name of Faculty Venue 5.A
Venue
1.C
Clinical Faculty 2.D
Clinical features, diagnosis, management and complications of HIV Ward 3.E
3
Name of Faculty posting 4.A
Venue 5.B
1.D
Microbiology micro-organisms Pharmacology 2.E
causing STDs Drug management of STDs Ward 3.A
4
Name of Faculty Name of Faculty posting 4.B
Venue Venue 5.C
Clinical Faculty
Clinical features, diagnosis, management and complications of STDs Ward
5
Name of Faculty posting
Venue
1.E
Community Medicine: 2.A
Forensic Medicine
Prevention and control of HIV 3.B
Death certification / sudden death Ward
6 and STDs
Name of Faculty posting 4.C
Venue
Name of Faculty
Venue 5.D
470
LEARNING OBJECTIVES
PHARMACOLOGY
Idd 1 Pha 1 ANTIMICROBIALS
Enlist different antimicrobial agents.

Describe the combinations of antimicrobial drugs.
Explain the Drug resistance.
Describe the Complications of antibiotic therapy.
Idd 1Pha2 Anti-malarial Drugs
Describe the mechanism of action of antimalarial drugs

Describe the common pharmacological effects of antimalarial drugs
Identify the common adverse effects of antimalarial drugs
Idd 1Pha 3 Drug used for Typhoid Fever
Enlist the drugs used in typhoid fever

Describe the mechanism of action of these drugs
Describe the common pharmacological effects of these drugs
Identify the common adverse effects of drugs used in typhoid fever
Idd 1 Pha 4 NSAIDS (NON-STEROIDAL ANTI-INFLAMMATORY DRUGS)
Describe the mechanism of action of NSAIDs

Describe the common pharmacological effects of NSAIDs
Identify the common adverse effects of NSAIDs
Identify the classification of NSAIDs
Describe the Common mechanism of action (cyclooxygenase inhibition)
Differentiate the selectivity to COX I and II
471
Idd1 Pha 5 ANTIDIARRHEAL AND ANTIMICROBIAL DRUGS
Describe the classification of anti- amoebic

Discussthe pharmacokinetics, mechanism of actions, adverse effects, drug interactions)
of these drugs.
Metronidazole.
Idoquinol
DiloxanideFuroate.
Enlist different antimicrobial agents
Explain Drug resistance and Complication of antibiotic therapy
Idd 1Pha 6 ANTIHELMINTHIC DRUGS
Discuss the important worms of helminthes group.

Describe the mode of action, pharmacokinetics, side effects, contraindication of:
o Praziquantal
o Niclosamide
o Albandazole
o Mebandazole
Idd 1 Pha 9 ANTI-RETROVIRAL AGENTS AND INTERFERON THERAPY
Enlist classes of drugs used for anti-retroviral therapy

Discuss the mechanism of action of commonly used drugs for anti-retroviral therapy
Describe indications and clinical uses of action of commonly used drugs for anti-retroviral
therapy
Explain the pharmacokinetics and adverse effects of commonly used drugs for anti-
retroviral therapy
PATHOLOGY
Idd 1 Pth 1 ACUTE AND CHRONIC INFLAMMATION

Revisit the pathological features of :
o acute and chronic inflammation
472
Idd1 Pth 2 PATHOLOGY OF MALARIA
Define Malaria
Enlist the types of plasmodium species causing malaria
Describe the pathogenesis with relevant lab tests
Idd 1Pth 4 PATHOPHYSIOLOGY OF SEPSIS /SIRS

Define SIRS, Sepsis, Septicemia and Septic Shock and describe its pathophysiology
Discuss the criteria for SIRS
Describe the microbial triggers
Enumerate the lab diagnosis
Describe the management for this disease.
Idd 1 Pth5 SPECIFIC LAB TESTS OF HIV TO MAKE PROPER DIGNOSIS

Describe the different laboratory tests done for diagnosis of HIV:
HIV antibody tests
Western Blot
ELISA
PCR
P24 antigen detection
Testing in neonates
MEDICINE
Idd 1 Med 1 MALARIA
Enlist the different clinical features of malaria

Identify the patho-physiology of malaria
Diagnose Malaria on the basis of various investigations
Treat Malaria and its complications
Idd 1 Med 2 TYPHOID CLINICAL FEATURES,DIAGNOSIS AND MANAGEMENT AND

COMPLICATIONS OF TYPHOID
Recognize possibility of Typhoid fever in the setting of acute fevers.

Enlist the clinical features and its complications.
Describe the ways to diagnose it and how to treat it.
Describe how to prevent Typhoid fever.
473
Idd 1 Med 4 APPROACH TO PATIENT WITH INFECTIOUS DIARRHEA AND DYSENTRY IN
ADULTS
Describe the acute diarrhea.

Enlist the Important causes of infectious diarrhea.
Describe the Measures to manage acute diarrhea and its prevention.
Idd 1 Med 5 HYDATID CYST ( Echinococcosis)
Define what is hydatid disease

Describe the brief life cycle of the parasite
Enlist clinical features and complications of hydatid disease
Enumerate different ways to treat this disease.
Idd 1 Med 6 VIRAL HEMORRHAGIC FEVER AND DENGUE
Describe viral haemorrhagic fever

Enlist the causative agents of dengue fever
Describe the symptoms of dengue fever
Describe the diagnosis, treatment and complications of dengue fever
Idd 1 Med 7 MUMPS
Discuss the epidemiology, pathogenesis, transmission of Mumps.

Describe the clinical features, diagnosis and treatment of mumps.
Idd 1 Med 8 LEPROSY
Describe the
Causative organism of leprosy
Types of leprosy
Clinical presentation of leprosy
Diagnosis of leprosy
Treatment strategy of leprosy
474
MICROBIOLOGY
Idd 1Mic 1 OVERVIEW OF MICROORGANISMS CAUSING FEVER
Describe the pathogenesis of fever in infectious diseases

List the common pathogens causing fever with sp. reference totyphoid,tuberculosis,
malaria and meningitis with relevant lab tests
Idd 1 Mic 2 CLOSTRIDIA
State the medically important types of gram positive bacilli.

List the various infections caused by clostridia and their pathogenesis.
State the relevant lab. diagnostic tests
Idd 1Mic PATHOGENS CAUSING DIARRHEA AND DYSENTRY I
BACTERIAL AND VIRAL PATHOGENS

Define diarrhea and dysentery and list the underlying causative pathogens
Describe pathogenesis of common gastrointestinal infections including diarrhea and food
poisoning
List the relevant diagnostic tests
Idd 1Mic 4 PATHOGENS CAUSING DIARRHEA AND DYSENTERY II
List the important pathogens causing diarrhea and dysentery

Describe the underlying pathogenesis in such infections and state relevant lab.
diagnostic methods
Idd 1Mic 5 WORM INFESTATIONS
List the clinically important parasites that infest humans

Describe mode of transmission and pathogenesis of diseases caused by worm infestations
Describe laboratory Diagnostic tests relevant to worm infestations
dd 1Mic 6 OVERVIEW OF MICRO-ORGANISMS THAT CAUSE FEVER WITH RASH

Enlist important viral pathogens that cause fever
Describe the pathogenesis of common fevers of viral origin
Discuss the relevant lab diagnostic method
475
Idd 1Mic 7 HUMAN IMMUNODEFICIENCY VIRUS STRUCTURE AND PATHOGENESIS
Definition of AIDS
Its structure and replication
Its Epidemiology and transmission
Pathogenesis and immunity of AIDS
Idd 1Mic 8 MIROORGANISMS CAUSING SEXUALLY TRANSMITTED DISEASES: STDS

Describe the
Pathogenesis of sexually transmitted diseases
Describe the epidemiology of sexually transmitted diseases
Explain the transmission of sexually transmitted diseases.
Enlist the clinical features of different sexually transmitted diseases.
Infectious diseases Module:
I. History taking skills
This is an interview with the patient / attendant with the aim of obtaining information useful in
formulating a diagnosis and providing appropriate medical care to the patient.
At the end of the session students should be able to:
Demonstrate correct method of history taking of three specific symptoms fever, diarrhea
and cough.
476
CASE BASED LEARNING
Idd 1 Cbl 1
Assess the degree of dehydration.
Decide which plan to follow to treat.
Enlist the relevant investigations.
Interpret the investigations.
Enumerate the common etiological agents causing diarrhea
Make a fluid plan of the patient
Idd 1 Cbl 2
Define SIRS, sepsis, severe sepsis and septic shock.

Identify the level of infection in particular patient.
Discuss the risk factors causing sepsis and septic shock.
Outline the treatment options in sepsis
TOPICS OF FORENSIC MEDICINE
Lectures for semester V (4 WEEKS OF INFECTIOUS Diseases Module will have INITIAL
LECTURES of given list for 16 weeks)
Introductory class:
Forensic Medicine & Sciences, Various Branches & their importance and utility in civilized
society
Legal Procedures:
a) Pakistans Legal System, Courts, their power & jurisdiction.
b) Forensic Sciences
c) Medical ethics
d) Laws in Relation to Medical Men
Toxicology:
a. General principles of toxicology
b. Diagnosis and principles of treatment of toxicological cases
c. Physio-chemical techniques
d. Drug dependence
e. Autopsy techniques in toxicological cases
477
Practicals of Forensic Medicine:
1. Introduction to Toxicology & Poisons; Law relevant to Poisons (PPC)

Dangerous drug act 1930& Rules, Drug act 1976
2. Classification of Poisons
Medico legal
Effecting organ / Tissue system
3. Routes of administration of poisons,
Factors modifying action of poisons
4. Fate / effects of poisons in the human body
Biotransformation
Common domestic / environmental toxicants
478
TOTAL
WEEKS/HOURS 1st 2nd 3rd 4th T1x100/T2 ROUND OFF
(T1)
PATHOLOGY 2.5 - 2.5 3.5 8.5 12.01 12
PHARMA. 4 3.5 2.5 3.5 13.5 19.08 19
C.M. 2.5 - - 2 4.5 6.36 6
F.M. 2 2.5 1 3.75 9.25 13.07 13
PAEDS. - 1 1 - 2 2.82 3
MICROBIOLOGY 1 4.5 2 1 8.5 12.01 12
MEDICINE 6 3 4 4 17 24.02 24
SKILL LAB - 1.5 1.5 - 3 4.24 4
SBL - 1.5 1.5 1.5 4.5 6.36 6
TOTAL(T2) 18 17.5 16 19.25 70.75 100.02 100
479
(SEMESTER-II)
THEORY
ASSESSMENT TOOLS MARKS WEIGHTAGE

SEMESTER
ATP 25
EXAM
PAPER-I 80%
One best Questions
20
based on CBL
Total 100
MODULE EXAM
EMQs 10
ATP 20
MODULE PAPER 20%
One best Questions
20
based on CBL
Total 100
STRUCTURED VIVA

SUMMATIVE
ASSESMEN
SEMESTER
EXAM
See Semester
PAPER-V-A Structured viva
T
Assessment Plan
ASSESSMENT TOOLS
Structured Feedback
ASSESSMENT DURING CBL SESSION Given to the Student by
Facilitator
NOTE: Paper II & V-B of Semester-5 Examination are Based on Hematology-2 Module.
Paper III & V-C of Semester-5 Examination are Based on Respiratory Sys -2 Module.
Paper IV & V-D of Semester-5 Examination are Based on CVS-2 Module.
480
CREDIT HOURS
SEMESTER-V
INFECTIOUS DISEASES-1 MODULE
Paper-I 3
IDD-1
Paper-IV-A 1.5
481
HEMATOLOGY MODULE
CODE: HEM 2
SEMESTER V
THIRD (3RD) YEAR M.B.B.S
482
Spiral Sem. Modules

II

4 Week
wks
Second th
Spiral th
Trauma, 6 week
3 week 8 Weeks
/ Burns 2 wk
2 Weeks
th
th
PARALLEL THEMES:
483
MODULE COMMITTEE
Dr. Mohammad Akbar Agha, Professor of Pathology, DIMC, OICD(Focal Person)

Dr. Rashid Qadeer, Assistant Professor of Medicine, Unit-III, DMC, CHK
Dr. MahayRookh, Associate Professor of Pharmacology, DIMC
Dr. AijazQureshi, AssociateProfessor of Physiology, SMC
Dr.RukhsanaRubeen, Associate Professor of Biochemistry, DMC
Dr.Shaheena Hanif, Assistant Professor Pediatrics, CHK, DUHS
Capt. Dr. FarhatMirza, Professor of Forensic Medicine, DMC, DUHS

Dr. NighatNisar, Professor of Community Medicine, DMC, DUHS
Documented by:
Dr.Tanzeela Khan(Department of Anatomy, Dow Medical College, DUHS)
Coordinated by:
Reviewed by:
MODULE COMMITTEE
484
RATIONALE
Knowledge of blood, immunity and inflammation is essential, as blood is responsible for the
supply of micronutrients, O2 delivery to the tissues and maintenance of homeostasis and body
responses and defense mechanisms against injurious agents and various diseases and their
diagnosis encountered in daily life.
To provide the basic knowledge of subject to the students to deal with patients suffering from
Hematological disorders, to take history, to examine patients, to know about sampling
techniques, relevant Laboratory tests, their interpretations, treatment regimens and prognostic
values of courses of variousHematologicalb & Immunological&Immuno-Haematological
disorders of adults and children, the students are always required to revisit the previous
leanings of Physiology, Histology and Biochemistry.
TERMINAL OBJECTIVE
Medical graduate after completion of 5 years training program should be able to:.
Describe pathogenesis of common hematological disorders

Recognize the clinical presentations of common hematological, immunological and
inflammatory disorders
Describe pathogenesis & clinical presentations of common coagulation & platelet disorders
Practice basic principles of management of hematological, immunological & inflammatory
disorders.
485
Lectures
Demo
Tutorials
Practical
CBL / SBL
Self Study
Library
Digital
spotting
Practical /
Skills Lab
One Best,
EMQS
viva
LEARNING FACULTY TOPIC/CONTENT
OBJECTIVES Assessment
Classify the Anaemia PHYSIOLOGY HEM 2 Phy 1 1

and its effects on the Physiological review of * *
body (presentation) in anemia(nutritional)/
adult and children. importance of red cell
indices & its co-
relation)
PATHOLOGY HEM 2 Pth 1 1

Classification of * *
anemia/anemia of
diminishederythropoies
is(iron deficiency
anemia, megaloblastic,
aplastic)
HEM 2 Pth 2 1
Autoimmune, *
hemolytic anemia
PEDIATICRICS HEM 2Ped 1 1

Assess, classify and * *
manage child with
anemia
Iron, B12 * *
treatment(hematinic,
erythropoietin, CSF)
MEDICINE HEM 2 Med 1 1
Approach to a patient * * *
with anemia
CASE BASE HEM 2 CBL 1 Hemolytic 1.5
LEARNING anemia *
486
Interpret the PATHOLOGY HEM 2 Pth 3 1
importance of Hemolyticanemia(HS, *
inherent G6PD, SCD)
hematological and
immunological
HEM 2 Pth 4 1
disorders (Hemo-
Thalassemia syndromes * *
globinopathies,
membrane defect in
HEM 2 Pth 5 1.5
RBCs, Enzyme
defects) Interpretation of CP *
report
normal/abnormal
HEM 2 Pth 6 1.5

Instruments and *
techniques used for
blood indices
PEDIATRICS HEM 2 Ped 2 1.5

Anemia of inadequate *
production
Recognize the cause PHYSIOLOGY HEM 2 Phy 2 1
of haemostatic Revision of extrinsic * * *
abnormalities: and intrinsic pathways
platelets and
coagulation disorders PATHOLOGY HEM 2 Pth 7 1
in adults and children Bleeding diathesis * * *
platelet disorders
HEM 2 Pth 8 1
Coagulation * * *
disorders(haemophilia,
vWD)

Coagulants, * * *
anticoagulants,
thrombolytics
with thrombotic
disorders
DIC, thrombotic, * * *
thrombocyticpurpura,
HUS
with bleeding disorders
487
take history, PATHOLOGY HEM 2 Pth 10 1
examination, Blood transfusion,rh * * *
interpret basic lab incompatibility
data to diagnose
HEM 2 Pth 11 1
hemolytic disease of
new born ( RH, ABO , Bone marrow *
Minor group transplantation
incompatibility) HEM 2 Pth 12 1 *
Transplantation
rejection

Immunosuppressants,i *
mmunomodulators
related to
transplantation
PATHOLOGY HEM 2 Pth 13 1.5

Bone marrow *
examinations, normal
and abnormal
HEM 2 Pth 14 1.5

Clinical chemistry, *
protein, electrophoresis
PEDIATRICS HEM 2 Ped 3 1

Diagnosis of hemolytic * * *
disease of new born, Rh
incompatibility
HEM 2 Ped 4 1
Coagulation disorders * * *
Management of * * *
transfusion reaction
and
erythroblastosisfetalis
CASE BASE HEM 2 Cbl 2 1.5

LEARNING Neonatal Jaundice ---- *
RH Incompatibility
take history, PHYSIOLOGY HEM 2 Phy 3 1

examination of Revision of leucopoiesis * * *
patients presents
488
with fever , MEDICINE HEM 2 Med 5 1
lymphadenopathy Approach to patient * * *
and with lymphadenopathy
hepatospleenomegaly with or without
and interpret basic splenomegaly
lab data to diagnose
Leukemia and
lymphomas
PATHOLOGY HEM 2 Pth 15 1 * * *

Hodgkins lymphoma

Lymphoma and * * *
leukemia in children

Non-hodgkins * *
lymphoma
Recognize and PATHOLOGY HEM 2 Pth 17 1

correlate history and Non-neoplastic white * * *
examination with the cells
non neoplastic disorders(infections,
disorders of WBCs inflammation)
specially in reference
to infections, HEM 2 Pth 18 1
inflammations, Overview and * * *
allergic, metabolic classification of
disorders and neoplastic proliferation
congenital anomalies. of WBCs
Recognize the clinical PHYSIOLOGY HEM 2 Phy 4 1.5

manifestations and Polycythemia *
correlate with the
history and lab data PATHOLOGY HEM 2 Pth 19 1
of Myelo- Myeloproliferative *
proliferative disorders disorders
e.g. CML,
Polycythemia
HEM 2 Pth 20 1
Myelodysplastic *
syndrome

Anemia in children *
489
Recognize the COMMUNITY HEM 2 CM 1 1
common causes of MEDICINE common causes of *
anaemias prevalent anaemias prevalent in
in our community our community
Recognize the FORENSIC HEM 2 For 1 Personal 1

establishment of MEDICINE identity 1 * * *
individuality of
person on the basis HEM 2 For 2 Personal
Age Sex Stature
1 * * *
identity 2
Features Hair Scars
Tattoos External
HEM 2 For 3 Personal 1
Peculiarities Race,
identity 3 * * *
Religion & Nationality
Dental patterns
HEM 2 For 4 1.5
fingerprints,
footprints or Osteometric indices of * *
handprints bones in determining
sex and race
HEM 2 For 5 Autopsy 1.5
protocol * *
HEM 2 For 6 Race 1.5
evidences along with * *
methods of preserving
them
Discuss medical ethics FORENSIC HEM 2 For 7 Laws 1
a code of conduct, MEDICINE related to medical man * * *
intellectually derived 1
by a group of medical HEM 2 For 8 Laws
professionals for a
1 * * *
related to medical man
specific need and
voluntarily followed 2
by the members of
the profession HEM 2 For 9 Laws 1
related to medical man
* * *
3
490
HEMATOLOGY MODULE
TIME TABLE
FIRST WEEK
Days 8:30 to 9:30 9:30 to 10:30 10:30 to 1:00 01:30 to 3.00
Gp A:VENUE
interpret of CP report: Normal, Microcytic,
Macrocytic
Gp B: Forensic Med:
Pathology Osteometric Indices Of Bones In Determining
Physiology Sex And Race
Physiological review of Classification of Anaemia NAME OF FACULTY VENUE
anaemia(nutritonal)/importanc Anemia of diminished Gp C: Clinical Chemistry: Instruments and
Clinical
DAY 1 e of red cell indices and its erythropoeisis (Iron def techniques used for Blood Indices; VENUE
correlation anemia, megaloblastic, aplastic Posting
Gp D: Physiology tutorial:
NAME OF FACULTY anemia) PolycythemiaVENUE
VENUE NAME OF FACULTY NAME OF FACULTY
VENUE
Gp E:Pediatrics : Anemia of inadequate
production: Congenital hypo-plastic anemia,
Acquired aplastic anemia VENUE(FACULTY
FROM PAEDS 1,2,3,)
Pharmacology
Pathology 1.B
iron ,B12 treatment
Hemolytic anemia 2.C
(hematinics, erthropoeitin, Clinical
DAY 2 (HS, G6PD, SCD) 3.D
Colony stimulating factors) Posting
NAME OF FACULTY 4.E
NAME OF FACULTY
VENUE 5.A
VENUE
Pediatrics
Cong hemolytic anemia (+
Sickle cell anemia) & IMNCI
(Assess, Classify and manage 1.C
Pathology child with anemia) 2.D
Thalassemia syndromes Hereditary spherocytosis, G6PD Clinical
DAY 3 3.E
NAME OF FACULTY deficiency, Posting 4.A
VENUE Pyruvate kinase Deficiency,
Acquired hemolytic anemia, 5.B
Autoimmune hemolytic anemia
NAME OF FACULTY
VENUE
1.D
Pathology COMMUNITY MEDICINE
2.E
Autoimmune hemolytic anemia
DAY 4 NAME OF FACULTY 3.A
NAME OF FACULTY
VENUE 4.B
VENUE
5.C
1.E
ClinicalFaculty: Medicine 2.A
BEHAVIORAL SCIENCES
approach to a pt with anemia Clinical
DAY 5 NAME OF FACULTY 3.B
NAME OF FACULTY Posting
VENUE 4.C
VENUE
5.D
HEMATOLOGY MODULE (SEMESTER V)
491
TIME TABLE SECOND WEEK (2)
Theme: Hemostatic abnormalities and blood transfusion
Days 8:30 to 9:30 9:30 to 10:30 10:30 to 1:00 01:30 to 3.00
Physiology Pathology
-Revision of Extrinsic and Bleeding diatheses Clinical
DAY 1
intrinsic pathways review Platelet disorders Posting
NAME OF FACULTYVENUE NAME OF FACULTYVENUE
Student week
Pathology
FORINSIC MEDICINE Coagulation Clinical Activities (Classes
DAY 2
disorders(hemophilia, vwd) Posting
NAME OF FACULTYVENUE
Suspended)
Pharmacology Clinical Faculty: Medicine
DAY 3 -Coagulants, anticoagulants, Approach To A Pt With Clinical
thrombolytics Thrombotic Disorders Posting
NAME OF FACULTYVENUE NAME OF FACULTYVENUE
Gp A:Pathology lab; Screening Tests for

bleeding and coagulation bdisorders
interpretation
Gp B: F.M VENUE
Pathology Gp C: Clinical Chemistry: Hb

ClinicalFaculty: Medicine Electrophoresis PATHO LAB
DIC, Thrombotic Thrombo-
Approach to a pt with Clinical
DAY 4 cyto-paenicpurpura, Hemolytic
bleeding disorders Posting Gp D:: History Taking, Lab Data
Uremic Syndrome
NAME OF FACULTYVENUE Interpretation&Diagnosis of hemolytic
NAME OF FACULTYVENUE disease of new born (RH, ABO, Minor
group incompatibilityVENUE
(PEADS. 1 TO 3 FACULTY)
Gp E: SBL Medicine Wards

1 to 5
Pediatrics Pathology 1.B

Diagnosis of hemolytic Blood transfusion, indications 2.C
DAY 5 disease of newborn-Rh reactions Rh incompatibility 3.D
incompatibility NAME OF FACULTYVENUE 4.E
NAME OF FACULTYVENUE 5.A
Pediatrics
Coagulation disorder:
Hemophilia A, B, C, 1.C
Vonwellibrand Disease, ITP, Clinical Faculty: Medicine 2.D
Platelets function Defect, Management of transfusion
Clinical 3.E
DAY 6 Disseminated intravascular reaction and
coagulation: Hemolytic erytheroblstosisfetlais Posting 4.A
uremic NAME OF FACULTYVENUE 5.B
syndrome,Thrombotic
thrombocytopenic perpura
VENUE(PEADS. III)
492
TIME TABLE Third WEEK (3)
Hematology MODULE
Theme: White Blood Cell Disorders

Days 8:30 to 9:30 9:30 to 10:30 10:30 to 1:00 01:30 to 3.00
Gp D:Pathology lab; Screening Tests for
bleeding and coagulation bdisorders
interpretation
Gp E: F.M VENUE
Pathology
Physiology Non neoplastic white cell Gp A: Clinical Chemistry: Hb
Clinical Electrophoresis PATHO LAB
DAY 1 Revision of leucopoiesis disorders(infections,
NAME OF FACULTYVENUE inflammation) Posting Gp B: History Taking, Lab Data
Interpretation&Diagnosisof hemolytic
disease of new born (RH, ABO, Minor
group incompatibility),VENUE(PAEDS. I)
Gp C: SBL Medicine Wards
1 to 5
Pathology 1.E
Overview and classification of 2.A
PEADIATRICS Clinical
DAY 2 neoplastic proliferation of 3.B
VENUE Posting
white blood cells 4.C (PAEDS.II) VENUE
NAME OF FACULTYVENUE 5.D
Gp A:Pathology Lab:
Histological Difference b/w normal white
cell, leukaemoid reaction &Malignant cell
ClinicalFaculty:Medicine
Approach to pt with Pathology Gp B: F.M VENUE
Clinical
DAY 3 lymphadenopathy with or Hodgkins lymphoma
without splenomegaly NAME OF FACULTYVENUE Posting Gp C: Self study
Gp D: Self study
Gp E: SBL MEDICAL WARDS
Pediatrics 1.B
Lymphoma and leukemia in Pathology
2.C
Non Hodgkin Clinical
DAY 4 children 3.D
Lymphoma (NHL) Posting
NAME OF FACULTYVENUE 4.E
5.A
1.C
Pharmacology Clinical Faculty: Medicine 2.D
DAY 5 Chemotherapeutics Agents Paraproteinemia 3.E
NAME OF FACULTYVENUE NAME OF FACULTYVENUE 4.A
5.B
1.D
2.E
Forensic Medicine Pathology
Clinical 3.A
DAY 6 NAME OF FACULTY Myeloproliferative Disorders
VENUE NAME OF FACULTYVENUE Posting 4.B
5.C
493
TIME TABLE WEEK (4)
Hematology MODULE
Theme: IMMUNOLOGICAL DISORDERS

Days 8:30 to 9:30 9:30 to 10:30 10:30 to 1:00 01:30 to 3.00
1-D PATHO LAB

PATHOLOGY PATHOLOGY
2-E FM HALL 101
Myeloproliferative Disorders Myelodysplastic Syndrome CLINICAL
DAY 1 3-A SELF STUDY
NAME OF FACULTY NAME OF FACULTY POSTING 4-B SELF STUDY
VENUE VENUE
5-C SBL
1-E
PATHOLOGY
2-A
COMMUNITY MEDICINE Bone Marrow Transplantation CLINICAL
DAY 2 3-B
NAME OF FACULTY NAME OF FACULTY POSTING 4-C
VENUE VENUE
5-D
PATHOLOGY LAB: BONE MARROW
EXAMINATIONS NORMAL AND
ABNORMAL
PSYCHIATRY
Follow the basic principal of PATHOLOGY GP B: : CLINICAL CHEMISTRY: PROTEIN
counseling and assessing the Transplantation rejection ELECTROPHORESIS PATHO LAB
DAY 3 CLINICAL
prognosis of various diseases NAME OF FACULTY
in children VENUE POSTING GP C: PEDIATRIC: ANEMIA IN CHILDREN
VENUE ALH
GP D: SBL: MEDICAL WARDS
PHARMACOLOGY
CLINICAL
Immuno suppressant, F.M POSTING 1.B
Immune Modulators, related NAME OF FACULTY 2.C
DAY 4
to transplantation 3.D
NAME OF FACULTY VENUE 4.A
VENUE
DAY 5
1.D
1.C 2.A
2.D Clinical
DAY 6 SELF STUDY 3.B
3.A Posting
4.B 4.C
DAY 8 MODULE TEST
494
objectives:
PHYSIOLOGY
Hem 2 Phy 1Physiological review ofanaemia
What is anemia?
Classification of anemias
Morphological classification
Pathophysiological classification
Functional classification
How do you diagnose anemia?
HEM 2 Phy 2 Polycythemia
Define polycythemia
Describe the pathophysiology of polycythemia
Explain the causes of polycythemia
Elaborate the management plan for the given pathology
HEM 2 Phy 3 Revision of extrinsic and intrinsic pathways
Intrinsic pathway of clotting

Extrinsic pathway of clotting
Clotting factors
Clinical conditions due to deficiency of clotting factors.
Clotting factors.
Von Willebrand disease (VWD
HEM 2 Phy 4 Revision of leucopoiesis
classify the different types of WBCs

know the basic structure and function of different types of WBCs
To understand the formation and maturation of WBCs
To know the disorders related to WBCs
495
PATHOLOGY
HEM 2 Pth 1 Classification of
anemia/anemia of diminishederythropoiesis(iron deficiency
anemia, megaloblastic, aplastic)
Hemopoiesis
Anemias of diminished erythropoesis
What is Megaloblasticanemia,itsetiology and pathogenesis
What is iron deficencyanemiaetiology and pathogenesis
What is Aplastic anemia,etiology and pathogenesis.
HEM 2 Pth 2 Autoimmune, hemolytic anemia
Immune hemolytic disease

Transfusion reaction
Hemolytic disease of newborn
Warm autoimmune hemolytic anemia
Cold autoimmune hemolytic anemia
Drug induced hemolytic anemia
HEM 2 Pth 3 Hemolyticanemia(HS, G6PD, SCD)
To define hemolytic anemia.

To explain types of hemolytic anemia.
To identify morphological features on peripheral blood.
To discuss pathogenesis involved in hemolytic anemia.
HEM 2 Pth 4 Thalassemia syndromes
To discuss Thalassemia Syndromes

To understand different types of mutations.
To explain pathogenesis of thalassemia syndromes.
To identify morphological features on peripheral blood smear
HEM 2 Pth 7 Bleeding diathesis platelet disorders
Describe the problems faced in diagnosing the bleeding disorders

Define bruising
496
Identify different sites of bleeding
Elaborate different types of bleeding
Describe types of bleeding disorders
Identify investigation techniques to identify the given pathology
Describe the management plan
HEM 2 Pth 8 Coagulation disorders(haemophilia, vWD)
The etiology of hemophilia

The pathogenesis and pathophysiology of hemophilia
The classification of hemophilia
Diagnose hemophilia based on clinical features and laboratory findings
HEM 2 Pth 9 DIC, thrombotic, thrombocyticpurpura, HUS
Define and explain Dissemminate Intravascular Coagulopathy (DIC)

Define and explain Thrombopoietic, ThrombocytopenicPerpura(TTP) and Hemolytic
Ureamic Syndrome (HUS)
HEM 2 Pth 10 Blood transfusion,rh incompatibility
Know the details of blood transfusion.

Describe the indications of blood transfusion.
Differentiate between types of blood components.
Recognise the different transfusion reactions that may occur and the treatment
required.
Recognise the signs and symptoms of a potential transfusion reaction.
HEM 2 Pth 11 Non-neoplastic white cells disorders(infections, inflammation)
Understand the different products of hematopoeisis

Explain the types of wbcs
Elaborate the white blood cell disorders
HEM 2 Pth 12 Overview and classification of neoplastic proliferation of WBCs
Know the classification of neoplastic prolifeartion of WBCs.
HEM 2 Pth 13 Hodgkins lymphoma
497
Describe lymphoma and its pathogenesis
Elaborate its clinical features
Evaluate the hematological and biochemical findings
Explain its management and treatment
HEM 2 Pth 14 Non-hodgkins lymphoma
What is lymphoma and its classifications

What is non hodgkins lymphoma
The classification and staging of non hodgkins lymphomas.
Its diagnosis and treatment.
HEM 2 Pth 15 Myeloproliferative disorders
The classification of Myeloproliferative Syndromes

Chronic Myeloid Leukemia
Polycythemia Vera
Essential Thrombocytosis
Myelofibrosis
HEM 2 Pth 16 Myelodysplastic syndrome
Describe the myelodysplatic disorders with its different system classifications.

Elaborate its clinical findings
Explain the diagnosis of MDS
Recognize the important investigation for MDS
HEM 2 Pth 17 Bone marrow transplantation
Definition of bone marrow transplantation.

Types of bone marrow transplantation.
Procedure of bone marrow transplantation
Application of bone marrow transplantation( uses of bone marrow).
Drugs used in bone marrow transplantation.
HEM 2 Pth 18 Transplantation rejection
Describe the transplantation rejection process.
498
PHARMACOLOGY
HEM 2 Pha 1 Iron, B12 treatment(hematinic, erythropoietin, CSF)
Sites of action of erythropoietin.

Explain the approved indications for treatment of anemia by erythropoietin, iron, folic
Describe the causes of different anemias.
Explain the type of anemia expected as a result of deficiencies of iron, erythropoietin,
Vitamin B12 and folic acid.
Describe the primary acid and Vitamin B12.
Describe the absorption of iron by the intestines.
Explain the treatment for iron toxicity or overdose.
HEM 2 Pha 2 Coagulants, anticoagulants, thrombolytics
How Blood Clots are formed.

How the blood clots are broken down?
What drugs can be used to regulate clotting?
How to rectify clotting deficiencies
HEM 2 Pha 3 Immunosuppressants,immunomodulators related to transplantation

Define immunopharmacology
Describe the mode of action of immunomodulators
Describe the mode of action immunosuppressant drugs
Recognize the general principles regarding immunostimulation
PEDIATICRICS
HEM 2Ped 1 Assess, classify and manage child with anemia
Define anemia in a child

Classify anemia in children
Describe different causes of anemia
Identify the risk factors for the given pathology
Elaborate management options for the given pathology
HEM 2 Ped 3 Diagnosis of hemolytic disease of new born, Rh incompatibility
Immune hemolytic disease

Transfusion reaction
Hemolytic disease of newborn
Warm autoimmune hemolytic anemia
499
Cold autoimmune hemolytic anemia
Drug induced hemolytic anemia
HEM 2 Ped 4 Coagulation disorders
Know the normal pathophysiological pathway of hemostasis.

Know the clinical presentation of different bleeding & coagulation disorders.
Should be able to investigate the patient.
Should know the treatment of common bleeding and coagulation disorders.
Should know the long term management of these disorders.
HEM 2 Ped 5 Lymphoma and leukemia in children
Define leukemia and lymphoma

Describe the pathophysiology of the given pathologies
Identify the causes, symptoms and signs
Elaborate the management plans
MEDICINE
HEM 2 Med 1 Approach to a patient with anemia
Describe the examination of a patient with anemia

Distinguish between the different types of anemia
Recognize anemia symptoms
Elaborate its causes
Evaluate its Laboratory investigations
HEM 2 Med 2 Approach to a patient with thrombotic disorders
Discuss hypercoaguable states

Focus specifically on the inherited hypercoaguable conditions
Briefly describe the mechanism behind each of the inherited thrombophilias
Review the hypercoaguable workup and when it is appropriately done
HEM 2 Med 3 Approach to a patient with bleeding disorders
Describe hemostasis
Elaborate the clinical aspects of bleeding disorders
Explain its history and physical examination
Differentiate between platelet defect and coagulation defect
Evaluate its laboratory findings on the basis of the defect
500
HEM 2 Med 5 Approach to patient with lymphadenopathy with or without splenomegaly
Provide an approach to the patient with lymphadenopathy

Be able to differentiate between benign and serious illness
Knowledgeable of nodal distribution and anatomic drainage
Present a substantial differential diagnosis
Indications for nodal biopsy
FORENSIC MEDICINE
HEM 2 For 1 Personal identity 1
Discuss identity or Identification means establishment of individuality of person.
Investigate age from ossification activity of the bones
Express :
o Identification of the living
o Identification of the dead
o Decomposed
o Anthropometry
o Stature from bones
HEM 2 For 7 Laws related to medical man 1
Discuss medical ethics that is A CODE OF CONDUCT, INTELLECTUALLY DERIVED BY A

GROUP OF MEDICAL PROFESSIONALS FOR A SPECIFIC NEED AND VOLUNTARILY
FOLLOWED BY THE MEMBERS OF THE PROFESSION
Define consent, types of consent, rules for taking consent ,

Criteria for valid consent
Define Medical Negligence and differentiate it from Error.
List duties of doctor and patient.
List different behaviors of doctor.
List and define types of negligence.
501
List and describe methods to avoid it.
List and describe defenses against negligence.
Salient features of Transplantation of Human Organs and Tissues Ordinance, 2007

Define Euthanasia, types, role of physician and related ethical issues.
Hematology Module:
II. Introduction toACLS
Title: Respiratory Arrest
Introduction / Rationale:
ACLS provider course is designed for health care providers, who either direct or participate in the
resuscitation of a patient in or out hospital.
The goal of the ACLS provider course is to improve the quality of care provided to the adult
victim of cardiac arrest or other cardiopulmonary emergencies.
At the end of this session students should able to
1. Describe the clinical situation in which the following airway adjuncts may be used for airway
management.
2. Demonstrate the correct method of insertion of following
a. Oropharyngeal airway (OPA).
b. Nasopharyngeal Airway (NPA).
c. Bag and mask ventilation.
d. Advanced airway (laryngeal mask Airway LMA)
Title: Cardiac Arrest
Introduction / Rationale:
ACLS provider course is designed for health care providers, who either direct or participate in the
resuscitation of a patient in or out hospital. The goal of the ACLS provider course is to improve the
quality of care provided to the adult victim of cardiac arrest or other cardiopulmonary emergencies.
502
At the end of this session students should be
1. Proficient in providing BLS care.
2. Identify different parts and functioning of manual defibrillator.
3. Demonstrate how to manage a patient of cardiac arrest.
CASE BASE LEARNING
HEM 2 CBL 1 HEMOLYTIC ANEMIA
Define hemolytic anemia.

Discuss the risk factors.
Enumerate the examination finding.
Discuss differentials diagnosis on the basis of history and examination.
Enlist investigation.
\
HEM 2 Cbl 2 NEONATAL JAUNDICE ----RH INCOMPATIBILITY
The pathophysiology of RH incompatibility

The clinical presentation and complications
The investigations and management
503
SUBJECT/TOTAL X
WEEKS/HOURS 1st 2nd 3rd 4th TOTAL ROUND OFF
100
PHYSIO. 1 1 1 1 4 8.60 9
PATHO. 4 4 5 3 16 34.41 34
PHARMA. 1 1 1 1 4 8.60 9
C.M. 1 - - 1 2 4.30 4
F.M. - 1 1 1 3 6.45 6
PAEDS. 1 2 2 - 5 10.75 11
CLINICAL 1 3 2 - 6 12.90 13
B.S. 1 - - 1 2 4.30 4
SBL - 1.5 1.5 1.5 4.5 9.68 10
TOTAL 10 13.5 13.5 9.5 46.5 100 100
504
HEMATOLOGY-2 MODULE
(SEMESTER-V)
THEORY

SEMESTER
ATP 25
EXAM

20
based on CBL
Total 100 80%
MODULE EXAM
EMQs 10
ATP 20
MODULE PAPER
One best Questions
20 20%
based on CBL
Total 100
STRUCTURED VIVA

SUMMATIV
ASSESME
SEMESTE
R EXAM
See Semester
NT
PAPER-V-B Structured viva

E
Assessment Plan
ASSESSMENT TOOLS
Structured Feedback
Facilitator
NOTE: Paper I & V-A of Semester-5 Examination are Based on Infectious Diseases Module.
Paper III & V-C of Semester-5 Examination are Based on Respiratory Sys -2 Module.
505
CREDIT HOURS
SEMESTER V
HEMATOLOGY-2 MODULE
II 3
Hematology-2
VB 1.5
506
RESPIRTORY MODULE
CODE: RSP 2
SEMESTER V
THIRD YEAR M.B.; B.S
507
Spiral Sem. Modules

II

4 Week
wks
Second th
Spiral th
Trauma, 6 week
3 week 8 Weeks
/ Burns 2 wk
2 Weeks
th
th
PARALLEL THEMES:
508
MODULE COMMITTEE:
Dr. Pyar Ali, Assistant Professor of Medicine, DMC, CHK, DUHS

Dr. Ghulam Murtaza, Associate Professor of Pediatrics, DMC, CHK, DUHS
Dr. Faisal Faiyaz Zuberi, Assistant Professor of Pulmonology, OICD, DUHS (Focal Person)
Dr. Nighat Rukhsana, Professor of Physiology, DIMC
Dr. Saud Hassan, Professor of Pharmacology, DMC
Dr. Rukhsana Rubeen, Associate Professor of Biochemistry, DMC
Dr. Naheed Khan, Associate Professor of Anatomy, DMC
Dr Naveed uz Zafar, Assistant Professor of Pathology, SMC
Documented by:
Coordinated by:

Reviewed by:
MODULE COMMITTEE
509
RATIONALE
Pakistan is a country with high prevalence of respiratory diseases particularly in children where
the leading cause of morbidity and mortality in children is Acute Respiratory Infection and
pneumonia.
During clinical practice a graduate will come across different types of respiratory failures. To be
able to manage these, the basis of oxygen administration and artificial ventilation has to be
understood. The understanding of air flow dynamics will enable the student to comprehend the
management of diseases like asthma, chronic bronchitis and their remedies. Asthma and
allergic respiratory diseases are on the rise in Pakistan due to increasing pollution. At the same
time the diseases related to smoking like lung cancer and chronic bronchitis are also on the rise
and a firm understanding of the respiratory system will enable the student to prevent such life-
style diseases through spreading relevant health education messages.
By the end of the respiratory module in MBBS course the students shall be able to:
1) Understand the normal and abnormal structures and functions of respiratory system.
2) Interpret the biochemical changes in the body related to the respiratory system with
reference of some common respiratory disorders.
3) Take history and perform a satisfactory physical examination of the respiratory system.
4) Describe normal changes that occur in respiratory system functioning from infancy to
old age.
5) Formulate an appropriate plan for evaluating patients with respiratory signs and
symptoms to achieve a reasonable differential diagnosis and to develop an investigative
and management plan.
6) Diagnose, manage and prevent common respiratory diseases.
510
BCQS, SEQS EMQS

WRITTEN ASSESS;
DIGITAL LIBRARY
SELF STUDY
TUTORIALS
PRACTICAL
LECTURES
SKILL LAB
LIBRARY
VIVA
SBL
OBJECTIVES Assessment
ANATOMY RSP 2 Ana 1 1

Review normal Overview of Anatomy
* *
anatomy and of Thorax (Wall Lungs
physiology of and Tracheobronchial
respiratory system. tree) Common
Congenital anomalies
PHYSIOLOGY RSP 2 Phy 1 1

Lung volume and
* *
capacities+ABGs
PATHOLOGY RSP 2 Pth 1 1

COPD 1
* *
Obstructive diseases
emphysema,
chronic bronchitis
Knowing the PATHOLOGY RSP 2 Pth 2 1

obstructive lung COPD 2
* *
diseases like chronic Asthma,
bronchitis, bronchiectasis
emphysema,asthma, + Atelectasis
and bronchiectasis,
andidentify the causes,
underlying patho-
physiology,
histopathology, clinical
presentation and
pharmacological and
clinical management in
511
adults and children.
PHARMACOLOGY RSP 2 Pha 1

Drugs used in
* *
ASTHMA 1
RSP 2 Pha 2
Drugs used in
* *
ASTHMA 2
MEDICINE RSP 2 Med 1

* *
Asthma
PHARAMCOLOGY RSP 2 Pha 3

* *
Bronchial Asthma
MEDICINE RSP 2 Med 2

* *
COPD/Resp Failure
clinical approach,
investigations &
diagnosis
COMMUNITY RSP 2 Com 1

MEDICINE
Air pollution
PHARMACOLOGY RSP 2 Pha 4 1.5

PRACTICAL Activity of Histamine
*
and antihistamine on
Bronchial smooth
muscles
PATHOLOGY RSP 2 Pth 3 1.5

PRACTICAL
*
HISTOPATHOLOGY OF
COPD
512
PEDIATRICS RSP 2 Ped 1 1.5
Childhood Asthma:
*
Classification and
management
SCENARIO BASED RSP 2 Sbl 1 1.5

LEARNING
PATHOLOGY RSP 2 Pth 4 1 *

Chronic Interstitial
Restrictive Diseases
Understand the RSP 2 Pth 5 1

* *
interstitial lung Granulomatous
diseases with diseases: sarcoidosis,
emphasis on hypersensitivity
occupational lung related diseases
diseases and
Identify the causes,
MEDICINE RSP 2 Med 3 1
underlying patho- * *
physiology, Clinical investigations
histopathology, & management of ILD
clinical presentation
and clinical
management
Knowing the
* *
Pulmonary infections-
pulmonary infections pneumonia, its types,
(pneumonias), identify pathogenesis
the causes, underlying
patho-physiology,
PEDIATRICS RSP 2 Ped 2 1
histopathology, clinical * *
presentation and Upper Respiratory
pharmacological and tract infections
clinical management. &management
Understand the
Management of
viral respiratory
infections (RSV) in
childrens.
RSP 2 Ped 3 1
* *
Lower respiratory
infections:
Pneumonia
513
* *
CAP: Community
Acquired pneumonia
clinical diagnosis,
severity assessment
and management
COMMUNITY RSP 2 Com 2 1

MEDICINE Nuclear Medicine
To understand the PATHOLOGY RSP 2 Pth 7 1

diseases of
* *
Pulmonary diseases
vascular origin; of vascular origin
identify the
Pulmonary embolism,
causes, underlying
hemorrhage,
patho-physiology,
infarction,
histopathology,
hypertension and
clinical
diffuse pulmonary
presentation and
hemorrhage
pharmacological
syndrome
and clinical
management.
MEDICNE RSP 2 Med 5 1

* *
PULMONARY
EMBOLISM
PHARAMCOLOGY RSP 2 Pha 5 1.5
PRACTICAL
* *
Pneumonia

* *
HISTOPATH OF CRPD
SKILL LAB 1.5

Examination of * *
Respiratory System
SBL 1.5
RSP 2 Sbl 2 * *

* *
Understand the Pulmonary
pathology, clinical Tuberculosis
presentation,
diagnosis and
approach in the
treatment of PHARMACOLOGY RSP 2 Pha 6 1
* *
514
Tuberculosis in Anti tuberculous
different clinical drugs 1
scenario.
RSP 2 Pha 7 1
* *
Anti tuberculous
drugs 2

* *
Adult Tuberculosis;
clinical diagnosis,
assessment and
management. (along
with MDR: Definition)
PEDIATRICS RSP 2 Ped 4 1

* *
Management of TB in
children

* *
Pulmonology
PFT
Interpretations
RSP 2 Med 8 1
* *
Arterial Blood Gases
(ABGs)

* *
Pulmonary tumors
Recognize the
pleural tumors;
identify the causes,
underlying patho-
physiology,
histopathology,
and clinical
management.
RSP 2 Pth 11 1
Pleural infection
* *
&Tumors

* *
Bronchogenic
515
Carcinoma
MEDICNE RSP 2 Med 10 1

Enable to Classify Classification &
* *
the types, Approach in pleural
underlying patho- effusion &
physiology, clinical Pneumothorax
presentation and
pharmacological and
clinical management
of pleural effusion
and pneumo-thorax.
PHARMACOLOGY RSP 2 Pha 8 1

Antitussive Drugs
* *
Review the
physiology of cough
and recognize
pharmacological
ways and means of
management.
Understand the COMMUNITY RSP 2 Com 2 1

interstitial lung MEDICINE Occupational lung
diseases with diseases
emphasis on
occupational lung
diseases
PHARMACOLOGY RSP 2 Pha 9 1.5

TUTORIAL Tuberculosis

Pneumonia
SCENARIO BASED RSP 2 Sbl 3 1.5
LEARNING SBL
516
TOPICS OF FORENSIC MEDICINE:
Personal identity
Laws relating to medical man
Professional misconduct
Professional negligence
Estimation of age , finger prints
FORENSIC MEDICINE TUTORIAL TOPICS:

General Toxicology
517
RESPIRATORY MODULE
TIME TABLE
FIRST WEEK
Days 8:30 to 9:30 9:30 to 10:30 10:30 to 1:00 01:30 to 3.00
CLINICAL ANATOMY
PRACTICALS
Overview of 1 Group-A: Pharmacology Practical :Activity
Antomy of Throrax CLINICAL of Histamine and antihistamine on Bronchial
(Wall Lungs and PHYSIOLOGY smooth muscles POWER LAB
DAY 1 Tracheobronchial Lung volume and 2. Group-B:Pathology : HISTOPATHOLOGY OF
capacities+ABGs Clinical Posting
tree) Common COPD
Congenital DR. SHEHLA
3. Group-C: F.M(General Toxicology)DR.
anomalies ALH
PARTAB HALL 101
DR. FARRUKH
ALH 4. SBL= D: Related To Hematology Module
Last week
PATHOLOGY
COPD 1 Pharmacology 1. B
Obstructive diseases Drugs used in
DAY 2 2. C
emphysema, ASTHMA 1 Clinical Posting
chronic bronchitis DR. SAUD 3. D
DR. IZHAR FATIMA ALH 4. A
ALH
PATHOLOGY
COPD 2 PHARMACOLOGYDr 1. C
Asthma, ugs used in 2. D
DAY 3
bronchiectasis ASTHMA 2 Clinical Posting 3. A
+ Atelectasis DR. SAUD
4. B
DR. IZHAR FATIMA ALH
ALH
Forensic Medicine
PULMONOLOGY
DAY 4 Personal Identity
Asthma Clinical Posting COLLEGE CLOSED
DR. MUSARRAT
ALH
ALH
Community PULMONOLOGY 1. D
Sciences COPD/Resp Failure 2. A
DAY 5 Air pollution clinical approach, Clinical Posting 3. B
DR. LUBNA investigations &
diagnosis 4. C
ALH
ALH
518
RESPIRATORY MODULE WEEK 2 (UPDATED)
Time Table Semester 5 (Session 2012)
DowUniversity of Health Sciences-
Theme; Restrictive Airway diseases + infections
Days 8:30 to 9:30 9:30 to 10:30 10:30 to 1:00 01:30 to 3.00
PRACTICALS
1 Group-C: Pharmacology Practical :Activity of
Pathology
Histamine and antihistamine on Bronchial smooth
Paediatrics
Childhood Asthma: muscles POWER LAB
Chronic interstitial
DAY 1 Classification and restrictive diseases 2. Group-D:Pathology : HISTOPATHOLOGY OF
Clinical Posting
management COPD
DR.IZHAR FATIMA
DR.GHULAM MURTAZA.
ALH ALH 3. Group-A: F.M(General Toxicology)DR. PARTAB
HALL 101
4. SBL= B: Related To Hematology Module Last
week MEDICAL WARDS
PATHOLOGY
Granulomatous diseases
Pulmonology 1. A
sarcoidosis,
DAY 2 Clinical investigations & Clinical Posting 2. B
hypersensitivity related
diseases. management of ILD 3. C
DR.IZHAR FATIMA ALH 4. D
ALH
DAY 3
PATHOLOGY
Paediatrics
Pulmonary infections- 1. D
Upper Respiratory tract
DAY 4 pneumonia, its types, Clinical Posting 2. A
infections &management
pathogenesis 3. B
DR.MUZAMMIL
DR.IZHAR FATIMA 4. C
ALH
ALH
PEDIATRICS Community medicine
DAY 5 Lower respiratory Nuclear Medicine
infections: Pneumonia DR.LUBNA RAZA Clinical Posting
DR.SAMINA TARIQALH ALH
Pulmonology
Forensic Medicine CAP: Community
Laws Relating to Medical Acquired pneumonia
DAY 6
Man clinical diagnosis, severity Clinical Posting SELF STUDY
CAPT. DR. FARHAT MIRZA assessment and
ALH management
ALH
519
RESPIRATORY MODULE WEEK III
TIME TABLE SEMESTER 5 (SESSION 2012) - Theme; Respiratory Infections
Days 8:30 to 9:30 9:30 to 10:30 10:30 to 1:00 01:30 to 3.00

PATHOLOGY: PRACTICALS
Pulmonary diseases of 1) GP=A Pharmacology Tutorial Pneumonia
vascular origin 2) GP=B Pathology HISTOPATH OF CRPD
Pulmonary embolism, Clinical faculty PATHO LAB
DAY 1 hemorrhage, PULMONARY Clinical Posting 3) GP=C1: Examination of Respiratory
infarction, EMBOLISM System
hypertension and
diffuse pulmonary ALH Skill Lab GP=C2. Self Study
hemorrhage 4) GP: D= Forensic Medicine General
syndrome toxicologyHALL 101
DR. AFTAB ALH 5) GP: E = SBL ALH (Peads. 1 Faculty )ALH
Pharmacology 1. B
Pathology 2. C
Anti tuberculous
DAY 2 Pulmonary drugs 1
Clinical Posting
3. D
Tuberculosis
ALH DR. SAUD 4. E
ALH 5. A (Peads, II Faculty)
Pharmacology 1. C
Anti tuberculous 2. D
DAY 3 B.S drugs 2
Clinical Posting
ALH 3. E
DR. SAUD 4. A
ALH
5. B (Peads, III Faculty)
Pulmonology
Adult Tuberculosis; COMMUNITY 1. D
clinical diagnosis, MEDICINE
DAY 4 Clinical Posting 2. E
assessment and Air pollution
3. A
management. (along DR. LUBNA RAZA
with MDR: Definition) 4. B
ALH
ALH 5. C (Peads, I Faculty)
Forensic medicine
Pediatrics: Clinical
Professional
presentation
DAY 5 misconduct
Management of TB DR. CAPT. FARHAT Clinical Posting
in children MIRZA
ALH ALH
FORENSIC
Clinical Faculty 1. E
MEDICINE
/Pulmonology 2. A
DAY 6 Professional
Negligence PFT Clinical Posting 3. B
DR. CAPT. FARHAT Interpretations 4. C
MIRZA
ALH 5. D (Peads, II Faculty)
ALH
520
RESPIRATORY MODULEWEEK IV
TIME TABLE SEMESTER 5 (Session 2012)
TUMORS OF RESPIRATORY SYSTEM
Days 8:30 to 9:30 9:30 to 10:30 10:30 to 1:00 01:30 to 3.00
PRACTICALS:
1.Pharmacology Group-A Tutorial
CLINICAL FACULTY tuberculosis
PATHOLOGY
DAY 1 Arterial Blood Gases 2.Pathology Group-B Pneumonia
Pulmonary tumours Clinical Posting 3..GP=C1: Self Study
(ABGs)
ALH
ALH
GP=C2. Examination of Respiratory SystemSkill
Lab
4. GP=D SBL, Medical Wards.
PULMONOLOGY/ 1. B
PATHOLOGY
Clinical Faculty/
DAY 2 Pleural infection 2. C
Bronchogenic &Tumors Clinical Posting
Carcinoma 3. D
ALH
ALH 4. A
PULMONOLOGY
Classification & 1. C
PHARMACOLOGY
DAY 3 Approach in pleural 2. D
Antitussive Drugs Clinical Posting
effusion & 3. A
ALH
Pneumothorax
ALH 4. B
F.M. Community Sciences

Estimation of Age + 1. D
Occuptional Lung
DAY 4 Finger Prints 2. A
DR. MUSARRAT Diseases Clinical Posting 3. B
SULTANA DR. LUBNA RAZA 4. C
ALH
ALH
PATHOLOGY
PHARMACOLOGY :
DAY 5 Asthma Bronchiectasis
Bronchial Asthma
+ Atelectasis Clinical Posting
ALH
ALH
DAY 6 SELF STUDY
DAY 1
MODULE TEST
521
LEARNING OBJECTIVES
ANATOMY
1) RSP 2 Ana 1OVERVIEW OF RESPIRATORY SYSTEM:
Describe an overview of anatomy of thorax (Wall Lungs and

Tracheobronchial tree) common congenital anomalies
PHYSIOLOGY
1) RSP 2 Phy 1 LUNG VOLUMES AND LUNG CAPACITIES:
Describe and discuss the importance of;
1. Different lung volumes including
Tidal Volume (TV)
Inspiratory Reserve Volume (IRV)
Expiratory Reserve Volume (ERV)
Residual Volume (RV).
2. Different lung capacities
Total Lung Capacity (TLC)
Vital Capacity (VC).
Functional Residual Capacity (FRC).
Inspiratory Capacity (IC).
522
PATHOLOGY
1. RSP 2 Pth 1 COPD Chronic Obstructive Lung Disease 01:
Describe the obstructive lung diseases like chronic bronchitis,

emphysema,asthma, and bronchiectasis
Identify the causes, underlying patho-physiology, histopathology, clinical
presentation in adults and children.
2. RSP 2 Pth 2 COPD-2:
Describe categories of asthma
Explain the pathogenesis of its categories
Discuss the immunological mechanisms of bronchial asthma and its triggering factors
Explain its morphological features
Define bronchiectasis
Describe its causes, pathogenesis and morphological features
Define atelectasis and describe its types
3. RSP 2 Pth 4 INTERSTITIAL LUNG DISEASES:
Define Interstitial lung diseases (ILD),
Describe its major categories
Explain the pathogenesis, morphology and clinical course of its important types
4. RSP 2 Pth 5 GRANULOMATOUS DISEASES:
Describe the pathological features of granulomatous diseases i.e:

Sarcoidosis
Hypersensitivity Pneumonitis
Pulmonary Eosinophilia
Desquamative Interstitial Pneumonia
PAP (Pulmonary Alveolar Proteinosis)
Respiratory bronchiolitis-associated ILD
523
5. RSP 2 Pth 6 PNEUMONIA:
Define pneumonia and classify it
Explain the following types of pneumonias with especial emphasis on their general
features and their causative agents:
a. Community acquired pneumonia
b. Hospital acquired pneumonia
c. Suppurative pneumonia
d. Aspirational pneumonia
e. Pneumonia in immunocompromised patient
PHARMACOLOGY
1) RSP 2 Pha 1 DRUGS USED IN ASTHMA 1:
Define asthma and its etiology
Discuss classes of asthma.
Describe characters of the mediators.
Explain the treatment of asthma
2) RSP 2 Pha 2 DRUGS USED IN ASTHMA 2:

Describe the signs and symptoms consistent with asthma
Differentiate the various severities of asthma
Summarize an appropriate treatment regimen for asthma of various severities
3) RSP 2 Pha 3 BRONCHIAL ASTHMA:
Describe the pharmacokinetics of inhaled drugs
Discuss the role of Inhaled- Corticosteroids in asthma
Explain the role of Montelukast in asthma
524
COMMUNITY MEDICINE
1) RSP 2 Com 1 AIR POLLUTION:
Describe the health effects due to air pollution
Explain air pollution solutions
2) RSP 2 Com 2 NUCLEAR MEDICINE:
Describe the biological effects of radiation
Discuss protection from radiations
PAEDIATRICS
1) RSP 2 Ped 1 CHILDHOOD ASTHMA CLASSIFICATION AND MANAGEMENT:
Discuss different types of childhoodasthma
Describe the management strategies for childhood asthma
2) RSP 2 Ped 2 ACUTE UPPER AIRWAY OBSTRUCTION IN CHILDREN:

Differentiate between child and adult airways
Discuss croup with its management
MEDICINE
1) RSP 2 Med 2 CHRONIC OBSTRUCTIVE PULMONARY DISEASE &

RESPIRATORY FAILURE:
Definition of COPD
Discuss spirometric classification of severity
525
Explain the risk factors, clinical features, investigations, management of COPD
Describe the types, pathophysiology of respiratory failure
2) RSP 2 Med 3 INTERSTITIAL LUNG DISEASES:

Explain pathogenesis & classification of interstitial lung diseases
Discuss the patient evaluation and treatment strategies
3) RSP 2 Med 4 COMMUNITY ACQUIRED PNEUMONIA:

Describe and discuss the management of community acquired pneumonia.
Respiratory system Module:

I. AUSCULTATION OF LUNG
Auscultation of lungs is one of the most important examination technique for assessing airflow
through the tracheao-bronchial tree. Together with percussion, it also helps the clinician assess
the condition of surrounding lungs & pleural space.
After the session the student should be able to:
Demonstrate the correct method of auscultation of lung.

Differentiate between normal , abnormal and adventitious breath sounds
Identify accurately at least six common breath sounds viz.
1. Normal breath sound
2. Bronchial breathing
3. Rhonchi
4. Crepitation/crackles
5. Pleural rub
6. Bronchophony
526
SCENARIO BASED LEARNING (SBL)
RSP 2 Cbl 1
Distinctions between different types of hypersensitivity

Mechanisms of immune-mediated damages
Examples of different types of hypersensitivity and overlap among them
Diagnostic test for hypersensitivity diseases
RSP 2 Cbl 2
Discuss the presentation of pulmonary TB in children

Send the relevant investigations
Interpret the investigations
Discuss the treatment plan
RSP 2 Cbl 3
Define Community acquired pneumonia (CAP)

Discuss typical & atypical microorganisms causing CAP and there common
presentations
Assess severity of CAP by CURB-65 Score
identify antibiotics according to severity
527
WEEKS/HOURS 1st 2nd 3rd 4th TOTAL T1x100/T2 ROUND OFF
PHYSIOLOGY 1 - - - 1 1.47 1
ANATOMY 1 - - - 1 1.47 1
PATHOLOGY 3.5 5.5 3.5 4.5 17 29 30
PHARMA 3.5 1.5 3.5 3.5 12 17.64 18
C.M. 1 1 1 1 4 5.88 6
F.M. 2.5 2.5 3.5 1 10.5 14.97 15
PAEDS. - 3 1 - 4 7.88 8
MEDICINE 2 3 3 3 11 15.88 16
SKILL LAB - - - 1.5 1.5 2.20 2
SBL 1.5 1.5 1.5 1.5 6 9.82 10
TOTAL
16 18 18 16 69 100 100
(WITHOUT SBL)
528
RESPIRATORY-2 MODULE
(SEMESTER-V)
THEORY

SEMESTER
ATP 25
EXAM
80%
PAPER-III One best Questions
20
based on CBL
Total 100
MODULE EXAM
EMQs 10
20%
ATP 20
MODULE PAPER
One best Questions
20
based on CBL
Total 100
STRUCTURED VIVA

SUMMATIV
ASSESME
SEMESTE
R EXAM
See Semester
NT
PAPER-V-C Structured viva

E
Assessment Plan
ASSESSMENT TOOLS
Structured Feedback
Facilitator
NOTE: Paper I & V-A of Semester-5 Examination are Based on Infectious Diseases Module.
Paper II & V-B of Semester-5 Examination are Based on Hematology -2 Module.
529
CREDIT HOURS
SEMESTER-V
RESPIRATORY-2 MODULE
PAPER-III 3
Respiratory-2
PAPER-V-C 1.5
530
CARDIOVASCULAR 02 MODULE
CODE: CVS 2
SEMESTER 5
THIRD YEAR M.B; B.S
531
Spiral Sem. Modules

II

4 Week
wks
Second th
Spiral th
Trauma, 6 week
3 week 8 Weeks
/ Burns 2 wk
2 Weeks
th
th
PARALLEL THEMES:
532
Document prepared by:
DR.TANZEELA KHAN.
(Department of Anatomy, Dow Medical College, DUHS)
MODULE COMMITTEE
Dr. Abdul Rauf Memon, Associate Professor of Medicine, DUHS

Dr. M. Nawaz Lashari, Assistant Professor of Cardiology, DUHS
Dr. Kelash Nankani, Assistant Professor of Physiology, DUHS
Dr. M. Yousuf Salat, Associate Professor of Pharmacology, DUHS
Dr. Yasmeen Hashim, Assistant Professor of DUHS
Dr. Haseena Chagani, Assistant Professor of Pediatrics Cardiology, DUHS
Dr. Rukhsana Rubeen, Assistant Professor DUHS
PARALLEL RUNNING SUBJECTS
Capt. Dr. Farhat Mirza, Professor of Forensic Medicine, DMC, DUHS

Dr. Nighat Nisar, Professor of Community Medicine, DMC, DUHS
Dr. Raza ur Rehman, Professor of Psychiatry, CHK, DUHS
Documented by:
Dr.Tanzeela Khan (Department of Anatomy, Dow Medical College & Principal
Office, DMC,DUHS)

Coordinated by:
Dr.Tanzeela Khan (Department of Anatomy, Dow Medical College & Principal
Office, DMC,DUHS)
Reviewed by:
MODULE COMMITTEE
CURRICULUM
533
RATIONALE
Diseases of the cardiovascular system are amongst the commonest causes of morbidity and
mortality all over the world. With increasing urbanization, their incidence is increasing in
Pakistan as well. Hypertension, ischemic heart disease, atherosclerosis and congenital and
rheumatic valvular disorders are he diseases which a medical graduate shall be expected to
manage after qualification. With the background of knowledge of anatomy, physiology,
pharmacology and the basics of cardiovascular diseases attained in the cardiovascular module of
the first cycle the student shall be able to build on the knowledge of clinical presentation,
diagnostic investigations and management of cardiovascular disorders.
TERMINAL OBJECTIVES
Medical graduate after completion of 5 years training program should be able to:
Describe pathogenesis & clinical presentations of common cardiovascular disorders
Take history, perform physical examinations of cardiovascular system and formulate
appropriate plan of investigations for making a diagnosis.
Interpret the investigations for diagnosis.
Describe the pharmacology of drugs used in the management of cardiovascular disorders.
Practice basic principles of management of cardiovascular disorders.
534
transfer, duration of teaching of content and the mode of assessment.
BCQS, SEQS EMQS

WRITTEN ASSESS;
DIGITAL LIBRARY
SELF STUDY
TUTORIALS
PRACTICAL
LECTURES
SKILL LAB
LIBRARY
VIVA
SBL
LEARNING
FACULTY
OBJECTIVES TOPIC/CONTENT
Modes of information Transfer Assessme

nt
Re-visit the anatomy ANATOMY 1

of cardiovascular CVS 2 Ana 1
* *
system.
Topographical anatomy
CVS 2 For of the heart, blood
supply of the heart
CARDIOLOGY CVS 2 Car 1 1 * *

Perform general Clinical examination of
physical examination precordium along with
(pulse, BP, cyanosis, relevant general
clubbing, anemia, physical examination.
edema, JVP),
examination of
CVS 2 Car 2 1
pericardium and * *
interpretation of
Approach to patient
findings.
with chest pain
dyspnoea, Palpitation
and its clinical
evaluation with
differentials
PAEDIATRICS CVS 2 Ped 1 1 * *

Clinical examination of
precordium along with
relevant general
physical examination in
children.
535
Identify imaging CARDIOLOGY CVS 2 Car 3 1
techniques used in
* *
the evaluation and its Cardiac imaging
interpretation. techniques and ETT
Interpret normal and
abnormal ECG and
can diagnose
common Cardiac
Arrhythmias / Blocks
and their
management.
CVS 2 Car 4 1 * *
Normal and non-
arrhythmias ECG
interpretation
FORENIC MEDO CVS 2 For 1 1.5

PRACTICALS * *
General toxicology
SKILL LAB CVS 2 Ugsl 1 1.5

* *
Clinical Examination of
CVS
PATHOLOGY CVS 2 Pth 1 1

Define
* *
Atherosclerosis, its Structure and function
etiology, of blood vessels and
pathogenesis, vessels diseases of vessel wall
affected, and including
complications. arteriosclerosis and
Define role of lipids congenital anomalies.
and platelets in Concepts of
atherosclerosis, role Arteriosclerosis and
of lipid lowering Atherosclerosis:
drugs (statins) and Epidemiology and risk
antiplatelets in factors
primary and
secondary prevention CARDIOLOGY CVS 2 Car 5 1 * *
Dyslipidemias and its
clinical value
PHARMACOLOGY CVS 2 Pha 1

* *
Drugs used in
treatment of
dyslipidemias.
536
Identify causes & risk PATHOLOGY CVS 2 Pth 2 1
factors of IHD,
* *
pathogenesis, clinical Angina pectoris, MI and
presentation as infarct modification by
angina, AMI. perfusion and chronic
ischemic heart disease.
Enlist and classify Angina pectoris,
drugs used for Myocardial Infarction
angina.
CARDIOLOGY CVS 2 Car 6 1 * *
Clinical evaluation of
IHD and its
complications with
management (Stable
Angina).
PHARMACOLOGY CVS 2 Pha 2 1

* *
Drugs used in the
treatment of angina.
CVS 2 Pha 3 1
* *
Anti platelets drugs,
anticoagulants,
thrombolytics,
CARDIOLOGY CVS 2 Car 7 1

Discuss evaluation of
* *
acute coronary Clinical evaluation of
syndrome, along with ACS and its
surgical interventions complications with
management.
CVS 2 Car 8 1
* *
PCI, CABG
PHARMACOLOGY CVS 2 Pha 4 1.5

PRACTICALS * *
Agonist
PATHOLOGY CVS 2 Pth 3 1.5

* *
Investigation an
Interpretation for
Hyper lipidemia
537
Define pathogenesis PATHOLOGY CVS 2 Pth 4 1
of Rheumatic fever,
* *
clinical and lab Rheumatic fever and
criteria for diagnosis Rheumatic heart
and complications. disease.

* *
Clinical manifestations,
diagnosis and
management of
rheumatic fever
Diagnose Valvular CARDIOLOGY CVS 2 Car 10 1

heart diseases on the
* *
basis of examination, Valvular Heart Diseases
its complications like Mitral Valve disease
infective endocarditis
and can manage CVS 2 Car 11 1
these diseases along * *
with its prevention. Aortic valve diseases
CVS 2 Car 12 1 * *
Infective endocarditis
Describe the PATHOLOGY CVS 2 Pth 5 1

pathophysiology of
* *
cardiac hypertrophy Cardiac Hypertrophy,
and its management pathophysiology and
progression to failure.
PHARAMCOLOGY CVS 2 Pha 5 1 * *

Drugs used in
treatment of cardiac
failure
Describe the PATHOLOGY CVS 2 Pth 6 1

pathogenesis of
* *
congenital heart Patho-physiology of
diseases and the role Congenital
of surgery heart disease
PAEDIATRICS CVS 2 Ped 2 1 * *

Approach to patient
with congenital heart
diseases
538
CARDIAC CVS 2 Car Sur 1 1
SURGERY * *
Role of Cardiac Surgery
in congenital and
acquired heart diseases

PRACTICALS * *
Treatment of angina
and Myocardial
Infarction.
SKILL LAB CVS 2 Ugsl 2 1.5

* *
ACLS
SBL CVS 2 Sbl 1 1.5

* *
SBL
Define Hypertension PATHOLOGY CVS 2 Pth 7 1
and Pre-
* *
hypertension, its Hypertensive vascular
grading, etiology, disease: pathogenesis,
associated and mechanism of
pathological changes, essential hypertension.
complications (TOD), Types and causes of
clinical & lab hypertension.
evaluation of Primary & Secondary
secondary causes, Hypertension
complications.
Antihypertensive
drugs, classification
and uses in different
clinical situations
PHARMACOLOGY CVS 2 Pha 7 1 * *
Anti-hypertensive
drugs- I
CVS 2 Pha 8 1 * *
Anti-hypertensive
drugs-II
PATHOLOGY CVS 2 Pth 8 1 * *

Cardiomyopathy:
Types, Causes and
539
Pathogenesis
List diseases of blood PATHOLOGY CVS 2 Pth 9 1

vessels, aneurysm,
* *
vasculitis and Aneurysm and
varicose veins, Vasculitis pathogenesis,
causes, presentations types and clinical
and complications. course.
SURGERY CVS 2 Sur 1 1 * *

Varicose veins and
DVTs
PATHOLOGY CVS 2 Pth 10 1 * *

Pericardial Diseases &
tumors of CVS
SURGERY CVS 2 Sur 2 1

Discuss the
* *
pathogenesis of Peripheral vascular
myocardial and diseases
Pericardial diseases,
their diagnosis and CARDIOLOGY CVS 2 Car 13 1 * *
management.
Cardiology
Interpretation of
Arrhythmias
PHARMACOLOGY CVS 2 Pha 9 1 * *

Anti-Arrhythmic drugs
I
CVS 2 Pha 10 1 * *
Anti-arrhythmic
Drugs-2

* *
Pharmacology Tutorial:
Treatment of HTN
PATHOLOGY CVS 2 Pth 11 1.5

* *
Histopathology
Practical:
Differentiate various
540
lesions of vascular
disorders
SBL CVS 2 Sbl 2 1.5

* *
SBL

Describe
* *
cardiomyopathy and Cardiomyopathy
pericardial diseases & pericardial diseases
Discuss CARDIOLOGY CVS 2 Car 15 1

tachyarrythmias
* *
Tachyarrhythmia
541
TIME TABLE
FIRST WEEK
Days 8:30 to 9:30 9:30 to 10:30 10:30 1:00 1:30-3:00
Day1 SELF STUDY

Day2 MODULE TEST
PRACTICALS
Clinical Faculty
Anatomy Cardiology 1) GP=A Forensic Medicine General
Topographical anatomy of the Approach to patient with chest toxicology HALL 101
Day3 heart, blood supply of the pain dyspnoea, Palpitation and its Clinical Posting 2) GP=B1 U/G skill lab : Clinical
heart clinical evaluation with Examination of CVS
Name of Faculty differentials GP=B2: Self Study
VENUE 3) GP: C Self Study
Name of Faculty VENUE
4) GP: D= PATHOLOGY: PATHO LAB
Clinical Faculty
1. B
Cardiology
Forensic Medicine 2. C
Clinical examination of precordium
Day4 Autopsy- I Clinical Posting 3. D
along with relevant general
Name of Faculty VENUE physical examination. 4. A
Clinical Faculty
Pediatrics
6. C
Clinical examination of
7. D
Day5 precordium along with Clinical Posting
relevant general physical 8. A
examination in children. 9. B
Clinical Faculty Clinical Faculty

Cardiology 1. D
Cardiology
Day6 Cardiac imaging techniques Normal and non-arrhythmias ECG Clinical Posting 2. A
and ETT interpretation 3. B
Name of Faculty VENUE Name of Faculty VENUE 4. C
542
Third Year SEMESTER 5 TIME TABLE WEEK II
THEME; ATHEROSCLEROSIS
Days 8:30 to 9:30 9:30 to 10:30 10:30 1:00 1:30-3:00
BASIC FACULTY PRACTICALS

PATHOLOGY 1) GP=A Pharmacology Tutorial Agonist
Structure and function of blood CLINICAL FACULTY 2) GP=B Pathology PATHO LAB lab
vessels and diseases of vessel wall CARDIOLOGY Investigation Interpretation for Hyper
Day1 including arteriosclerosis and lipidemia (Clinical Patho)
congenital anomalies. Dyslipidemias and its clinical CLINICAL POSTING
3) GP=C1: : U/G skill lab : ACLS
Concepts of Arteriosclerosis and value
Skill Lab GP=C2. Self Study
Atherosclerosis: Epidemiology and Name of Faculty VENUE.
risk factors 4) GP: D= Forensic Medicine General
toxicology HALL 101
5) GP: E = SBL MEDICINE WARDS
Day2
PUBLIC HOLIDAY
BASIC FACULTY
PATHOLOGY BASIC FACULTY 1. B
Angina pectoris, MI and infarct PHARMACOLOGY 2. C
Day3 modification by perfusion and
Drugs used in treatment of CLINICAL POSTING 3. D
chronic ischemic heart disease.
dyslipidemias.
Angina pectoris, Myocardial 4. E
Infarction Name of Faculty VENUE 5. A
CLINICAL FACULTY
CARDIOLOGY 1. C
BASIC FACULTY
Clinical evaluation of IHD and its PHARMACOLOGY 2. D
Day4 complications with management Drugs used in the treatment CLINICAL POSTING 3. E
(Stable Angina). of angina.
4. A
Name of Faculty Name of Faculty VENUE
5. B
VENUE
BASIC FACULTY 1. D
CLINICAL FACULTY
PHARMACOLOGY
CARDIOLOGY 2. E
Day5 Anti platelets drugs,
Clinical evaluation of ACS and its 3. A
anticoagulants,
complications with management.
thrombolytics, 4. B
Name of Faculty VENUE VENUE 5. C
1. E
CLINICAL FACULTY
Day6 CARDIAC SURGERY Forensic Medicine 2. A
Autopsy- II CLINICAL POSTING
PCI, CABG 3. B
Name of Faculty VENUE Name of Faculty VENUE 4. C
5. D
543
SEMESTER 5 (SESSION 2012) TIME TABLE WEEK III
-THEME; RHEUMATIC FEVER AND OTHER CONGENITAL AND ACQUIRED CARDIAC DISEASES
Days 8:30 to 9:30 9:30 to 10:30 10:30 1:30 1:30-3:00

PRACTICALS
1) GP=A Pharmacology Tutorial,
BASIC FACULTY
Treatment of angina and Myocardial
Pathology CLINICAL FACULTY Infarction.
Rheumatic fever and CARDIOLOGY
Day1 2) Self-study
Rheumatic heart Clinical Posting
Valvular Heart Diseases 3) GP=C1+ B1 U/G skill lab
disease.
Name of Faculty Mitral Valve disease GP=C2+B2 Self Study
VENUE Name of Faculty VENUE 4) GP: D= Forensic Medicine General
toxicology HALL 101
5) GP: E = SBL (medicine wards)
CLINICAL FACULTY
CARDIOLOGY
BASIC FACULTY 1. B
Clinical manifestations, PATHOLOGY
2. C
Day2 diagnosis and Cardiac Hypertrophy,
management of pathophysiology and Clinical Posting 3. D
rheumatic fever progression to failure. 4. E
Name of Faculty Name of Faculty VENUE 5. A
VENUE
BASIC FACULTY
BASIC FACULTY 1. C
PATHOLOGY
PHARMACOLOGY
Patho-physiology of 2. D
Day3 Drugs used in treatment
Congenital Clinical Posting 3. E
of cardiac failure
heart disease
VENUE 5. B
10. D
CLINICAL FACULTY 11. E
Day4 PEDIATRICS
Clinical Posting 12. A
Approach to patient with congenital heart diseases
Name of Faculty VENUE 13. B
14. C
CARDIAC SURGERY
FORENSIC MEDICINE
Role of Cardiac Surgery in
Day5 Autopsy III
congenital and acquired Clinical Posting
Name of Faculty
heart diseases
VENUE
CLINICAL FACULTY 6. E
CLINICAL FACULTY
CARDIOLOGY CARDIOLOGY
Day6 7. A+B
Infective endocarditis Clinical Posting
Name of Faculty Aortic valve diseases 8. C
VENUE Name of Faculty VENUE
9. D
544
SEMESTER 5, 3rd Year (SESSION 2012) TIME TABLE WEEK IV
-Theme; Hypertension
DAYS 8:30 to 9:30 9:30 to 10:30 10:30 1:00 1:30-3:00
PRACTICALS
PATHOLOGY 1) GP=A Pharmacology Tutorial:
Hypertensive vascular disease: Treatment of HTN
pathogenesis, and mechanism of 2) GP=B Histopathology
PHARMACOLOGY Practical: Differentiate various
essential hypertension. Types
Day1 Anti-hypertensive drugs- I CLINICAL lesions of vascular disorders
and causes of hypertension.
Name of Faculty POSTING
Primary & Secondary 3) GP=C2 U/G skill lab
VENUE
Hypertension GP=C1 Self Study
Name of Faculty
4) GP: D= Forensic Medicine
VENUE
General toxicology HALL 101
5) GP: E = SBL
1. B
PATHOLOGY
PHARMACOLOGY 2. C
Day2 Cardiomyopathy: Types, Causes CLINICAL
Anti-hypertensive drugs-II 3. D
and Pathogenesis POSTING
Name of Faculty VENUE 4. E
5. A
1. C
COMMUNITY MEDICINE
FORENSIC MEDICINE Role of diet and nutrition 2. D
Day3 CLINICAL
Autopsy- IV / lifestyle modification 3. E
POSTING
Name of Faculty VENUE Name of Faculty 4. A
VENUE
5. B
PATHOLOGY 1. D
CLINICAL FACULTY
Aneurysm and Vasculitis
Day4 Surgery CLINICAL 2. E
pathogenesis, types and clinical
Varicose veins and DVTs POSTING 3. A
course.
Name of Faculty VENUE 4. B
5. C
CLINICAL FACULTY
PATHOLOGY Surgery
Day5 Pericardial Diseases & tumors of Peripheral vascular CLINICAL
CVS diseases POSTING
Name of Faculty VENUE Name of Faculty VENUE
1. E
CLINICAL FACULTY
PHARMACOLOGY CLINICAL 2. A
Day6 Cardiology
Anti Arrhythmic drugs I POSTING
Interpretation of Arrhythmias 3. B
Name of Faculty VENUE 4. C
5. D
545
SEMESTER-V, 3rd Year (SESSION 2012)
TIME TABLE WEEK V
DAYS 8:30 to 9:30 9:30 to 10:30 10:30 1:00 1:30-3:00
CLINICAL FACULTY CLINICAL FACULTY

PHARMACOLOGY
CARDIOLOGY
Day1 Anti-arrhythmic CLINICAL Tachyarrythmias
Cardiomyopathy
Drugs-2 POSTING
& pericardial diseases Name of Faculty VENUE
REVISION CLASS (OPTIONAL)

Day2
ECG
CLINICAL Self Study
POSTING
Day3
Self Study CLINICAL Self Study
POSTING
CLINICAL
Day4 Self Study POSTING
Day5
Module Exam COLLEGE CLOSED
CLINICAL
Day6
Self Study WARD TEST
Self Study
546
LEARNING OBJECTIVES
ANATOMY
CVS 2 Ana 1 TOPOGRAPHIC ANATOMY AND BLOOD SUPPLY OF THE HEART
Discuss position of the heart

Discuss surface anatomy of the heart
Identify the borders and surfaces of heart
Describe the blood supply of the heart
CARDIOLOGY
CVS 2 Car 1 CLINICAL EXAMINATION OF PRECORDIUM ALONG WITH RELEVANT GENERAL
PHYSICAL EXAMINATION
Inspect the patient
Feel the pulses, rate and rhythm
Inspect the neck veins
Palpate the precordium
Auscultate the precordium
Palpate the peripheral pulses
CVS 2 Car 2 APROACH TO CHEST PAIN DYSPNEA AND PALPITATION
Describe that how to approach to a patient with chest pain

Discuss how to approach to dyspnea and palpitation.
CVS 2 Car 3 CARDIAC IMAGING TECHNIQUES
Discuss the tests for Cardiac Imaging:

ETT
MRI
CT SCAN
ECHO, STRESS & TRANS-ESOPHAGEAL ECHO
ECG
547
CVS 2 Car 5 DYSLIPIDEMIA & ITS CLINICAL VALUE
Discuss different cardiovascular diseases

Describe the production of VLDL, LDL, HDL
Explain atherosclerosis and lipid accumulation
Classify Dyslipidemias with its types
Discuss prevention and treatment of dyslipidemias
CVS 2 Car 6 CLINICAL EVALUATION OF STABLE ANGINA
Describe the pathogenesis of stable angina

Discuss clinical presentation of stable angina
Classify stable angina
Explain diagnostic work up, pros and cons
Describe the management options of stable angina
CVS 2 Car 8 CORONARY ARTERY BYPASS, PCI
Discuss coronary artery bypass , its method, and indications

Describe the anatomy involved in CABG
Explain grafts used in CABG
CVS 2 Car 10 MITRAL VALVE LESIONS
Explain the normal anatomy of mitral valve

Enlist causes of mitral stenosis
Discuss the clinical manifestations of mitral stenosis
Describe the management of mitral stenosis
CVS 2 Car 11 APPROACH TO THE PATIENT WITH AORTIC VALVE DISEASE:
Discuss function and physiology of aortic valve

Describe pathophysiology and management of aortic stenosis
CVS 2 Car 13 INTERPRETATION OF ARRHYTHMIAS:
Define and describe arrthymias, normal sinus rhythm, bradyarrythmias, sinus bradycardia,
sinoatrial exit block, junctional rhythm, idioventricular ryhthm, paroxysmal tachycardia,
atrioventricular blocks, atrial and ventricular Flutter, atrial and ventricular fibrillation.
548
PATHOLOGY
CVS 2 Pth 1 ARTERIOSCLEROSIS & ATHEROSCLEROSIS (EPIDIMIOLOGY AND RISK FACTORS
Discuss etiology, risk factors for arteriosclerosis & atherosclerosis

Describe the pathogenesis of arteriosclerosis & atherosclerosis
Describe the clinical expression of arteriosclerosis and atherosclerosis
CVS 2 Pth 2 ANGINA PECTORIS , MYOCARDIAL INFARCTION, CHRONIC ISCHAEMIC HEART

DISEASE:
Describe the pathogenesis of:
Angina pectoris
Acute coronary syndrome
Myocardial infarction
Sudden cardiac death
Chronic Ischaemic Heart Disease
CVS 2 Pth 4 RHEUMATIC FEVER AND RHEUMATIC HEART DISEASE:
Describe etiology, epidemiology and pathogenesis of rheumatic fever and rheumatic

heart disease
Discuss clinical manifestations & laboratory findings
Enlist differential diagnosis
CVS 2 Pth 6 PATHOPHYSIOLOGY OF CONGENITAL HEART DISEASE:
Describe the pathophysiology of:

Congenital heart defects
Acyanotic heart diseases
Cyanotic heart diseases
Left to right shunts
Right to left shunts
549
HYPERTENSIVE VASCULAR DISEASE: TYPES OF HYPERTENSION, PATHOGENESIS,
CVS 2 Pth 7
CAUSES AND MECHANISM OF ESSENTIAL AND SECONDARY HYPERTENSION:
Define the blood pressure and hypertension

Describe causes, pathogenesis, and mechanism of primary and secondary hypertension
Explain morphological changes in the blood vessel wall
Describe clinical manifestations of hypertension
CVS 2 Pth 8 CARDIOMYOPATHIES: TYPES, CAUSES AND PATHOGENESIS:
Describe the:
Types of cardiomyopathies
Causes of cardiomyopathies
Morphology of cardiomyopathies
Pathogenesis of cardiomyopathies
Clinical manifestations
CVS 2 Pth 9 ANEURYSM AND VASCULITIS PATHOGENESIS, TYPES AND CLINICAL COURSE.
Define aneurysm and types of aneurysm alongwith pathogenesis and clinical course
Describe pathogenesis , clinical course and classification of vasculitis
CVS 2 Pth 10 PERICARDIAL DISEASES AND TUMOURS OF CVS:
Describe pericarditis, its mechanism of disease, causes, and pathogenesis

Discuss tumors of pericardium and blood vessels
PHARMACOLOGY
CVS 2 Pha 1 DRUGS USED IN DYSLIPIDEMIAS:
Describe the pharmacological aspects of drugs used in dyslipidemias:

Bile acid sequestrants
HMG-CoA reductase inhibitors
Fibric acid derivatives
Niacin
550
CVS 2 Pha 2 ANTIANGINAL DRUGS:
Classify different anti-anginal drugs

Describe the mechanism of action, side effects of anti-anginal drugs
CVS 2 Pha 3 ANTI COAGULANTS, THROMBOLYTICS AND ANTI-PLATELET AGENTS
Describe the classification of anticoagulants

Describe pharmacological aspects of:
Heparin (Mode of action ,pharmakokinetics,low molecular weight heparin, and
side effects of heparin,treatment of heparin overdose)
Oral anticoagulants. (Mode of action,pharmakokinetics and indications and
contraindications)
Thrombolytic drugs. (pharmakokinetics,therapeutic uses,adverse effects)
Antiplatelet agents (Inhibition of prostaglandin synthesis).
Aspirin (MOA,Inhibitors of ADP pathways of platelets)
Dosage of clopidogrel, adverse effects
CVS 2 Pha 7 ANTI-HYPERTENSIVE DRUGS-01:
Classify anti-hypertensive drugs

Describe therapeutic uses, adverse effects, contraindications of alpha-blockers
CVS 2 Pha 8 ANTI-HYPERTENSIVE DRUGS -02:
Describe mixed a-b antagonists types, mechanism of action, therapeutic uses

Discuss calcium channel blockers, types, mechanism of action, advantage over other
vasodilators, adverse effects and contraindications
COMMUNITY MEDICINE
CVS 2 Com 1 ROLE OF NUTRITION AND LIFE STYLE MODIFICATION IN CVD
Discuss the role of nutrition and lifestyle modification in cardiovascular diseases
SURGERY
CVS 2 Sur 1 VARICOSE VEINS
Definition of varicose veins

Discuss signs and symptoms of varicose veins.
Enlist causes of varicose veins.
Describe stages of varicose veins
Discuss treatment of varicose veins
551
PAEDIATRICS
CVS 2 Ped 1 INFECTIVE ENDOCARDITIS
Recognize risk factors, signs & symptoms of infective endocarditis (IE).
Discuss approaches to diagnose IE.
Appreciate importance of rapid treatment.
Anticipate possible complications.
Cardiovascular system module
I. Auscultation of Heart
Introduction / Rationale
Auscultation of heart often presents with difficulty and requires great deal of practice for the
beginner. The skilled examiner listens for specific findings, focusing particularly on cardiac
cycle. It is important to identify systole and diastole and added sounds if present e.g. murmurs
Learning objectives
After the session the student should be able to:
Describe the different parts of stethoscope and its uses.

Demonstrate the correct method of auscultation of heart.
Identify different components of normal heart sounds viz.
S1
S2
Identify common abnormalities of heart sounds viz.

Murmur of
Mitral stenosis
Mitral regurgitation
Aortic stenosis
Aortic regurgitation
VSD
Pericardial rub
552
SCENARIO BASED LEARNING
CVS 2 Cbl 1
Describe the pathogenesis of coronary artery disease and associated risk factors
Diagnose ischemic heart disease on the basis of history, clinical examination and lab evaluation
along with interpretation of ECG
Differentiate angina, unstable angina and acute myocardial infarctio
CVS 2 Cbl 2
Understand the pathogenesis of coronary artery disease and associated risk factors
Can diagnose ischemic heart disease on the basis of history, clinical examination and lab
evaluation along with interpretation of ECG
Can differentiate angina, unstable angina and acute myocardial infarction
Can manage angina, acute MI and acute pulmonary edema
CVS 2 Cbl 3
Define Acute Rheumatic Fever.

Predispoing factors for RF.
Relation of tonsilopharingits to systematic and cardiac manifestations RF.
Anatomy of Mitral ,aortic and other valves.
Laboratory changes
ECG and X-Ray changes.
ECHO Cardiographic findings.
Diagnostic criteria for rheumatic fever.
Counsel regarding treatment and referral
CVS 2 Cbl 4
1. Define Normotensive/ hypertensive .

2. Explain lab investigations, X-ray and ECG of this patient
3. Explain the management of given pathology.
553
4th & SUBJECT/TOTAL X
WEEKS/HOURS 1st 2nd 3rd TOTAL
5th 100
CARDIOLOGY 4 4 2 2 12 24
PATHO. - 2 3 5 10 24
PHARMA. 1 3 1 5 9 18
C.M. - - - 1 1 2
F.M. 1 1 1 1 4 8
Cardiac surgery - - 1 2 3 6
Paeds Cardiology 1 - 4 - 5 10
SBL - 1.5 1.5 1.5 4.5 10
TOTAL 7 11.5 13.5 15.5 50 100
554
CARDIOVASCULAR-02 MODULE
(SEMESTER V)
THEORY

SEMESTER EXAM
ATP 25
PAPER-IV
20
based on CBL
Total 100
MODULE EXAM
EMQs 10
ATP 20
MODULE PAPER
One best Questions
20 20%
based on CBL
Total 100
STRUCTURED VIVA

SUMMATI
ER EXAM
ASSESM
SEMEST
See Semester
ENT
VE
PAPER-V- D Structured viva

Assessment Plan
ASSESSMENT TOOLS
Structured Feedback
Facilitator
NOTE: Paper I & V-A of Semester 5 Examination are Based on Infectious Diseases Module.
Paper II & V-B of Semester 5 Examination are Based on Hematology-2 Module
Paper III & V-C of Semester 5 Examination are Based on Respiratory-2 Module.
555
CREDIT HOURS
SEMESTER-V
PAPER-IV 3
CVS-02
PAPER- V-D 1.5
556
ASSESSMENT PLAN, SEMESTER-5
CREDIT
HOURS
Infectious Diseases- 1
Module 40 Marks
50
I (Semester Theory)
Infectious Diseases- 1
Marks 3
10 Marks
(Module Exam)
Hematology Module
40 Marks
II Hematology Module
10 Marks
Marks 3
(Module Exam)
Respiratory Module
40 Marks
III Respiratory Module
10 Marks
Marks 3
(Module Exam)
Cardiovascular Module
40 Marks
IV Cardiovascular Module
10 Marks
Marks 3
(Module Exam)
Infectious Diseases
a Module 50 Marks 1.5
(Viva)
Hematology Module
b 100 1.5
V (Viva)
Respiration Module
Marks
c
(Viva)
25 Marks 1.5
Cardiovascular Module
d
(Viva)
25 Marks 1.5

557
558
SEMESTER -6
GI and Liver-II Module 8 Weeks 9 Credit Hours
Renal & Excretory System-II Module 4 Weeks 4.5 Credit Hours
Endocrinology-II Module 4 Weeks 4.5 Credit Hours
559
GIT & LIVER & NUTRITIONAL DISORDERS
MODULE
CODE: GIL 2
SEMESTER 6
THIRD (3RD) YEAR M.B;B.S
560
Spiral Sem. Modules

II

4 Week
wks
Second th
Spiral th
Trauma, 6 week
3 week 8 Weeks
/ Burns 2 wk
2 Weeks
th
th
PARALLEL THEMES:
561
GASTRO INTESTINAL TRACT AND LIVER-2
MODULE COMMITTEE
Prof. Aisha Mehnaz, Professor of Paediatrics, DUHS
Dr. BadarFaiyazZuberi, Associate Professor of Medicine, DUHS
Dr. Sajida Qureshi, Assistant Professor of Surgery, DUHS
Dr. Sheeraz Shakoor Siddiqui, Assistant Professor of Surgery, DUHS
Dr. Talat Yasmeen, Professor of Anatomy, DUHS
Dr. Sarwar Qureshi, Assistant Professor of Anatomy, DUHS
Dr. Samina Rizvi, Associate Professor of Pathology, DUHS
Dr. Nadeem A. Sheikh, Assistant Professor of Pharmacology, DUHS
Dr. Nadeem, Assistant Professor of Pathology, DUHS
Dr. Rukhsana Rubeen, Associate Professor, DUHS
Capt. Dr. Farhat Mirza, Professor ofForensic Medicine, DUHS

Dr. Nighat Nisar, Professor of Community Medicine, DUHS
Dr. Raza ur Rehman, Professor of Psychiatry, DUHS



Module committee
562
RATIONALE
Gastrointestinal tract and liver are essential for digestion absorption and assimilation of food
and production of energy generating metabolites. Liver is central to all metabolic activities of
human body. A large number of disorders afflict both GIT and liver which affect their function.
Understanding the pathogenesis, recognizing their presentation, ordering and interpreting
investigations and management requires a sound understanding of these systems.
With the base formed in the GIT module in the first, basic sciences spiral, the student in the
current module shall be able acquire the understanding of diseases of GIT and liver and their
management.
TERMINAL OBJECTIVE
Describe pathogenesis & clinical presentations of common gastrointestinal disorders

Evaluate nutritional disorders in pediatric & adult patients.
Perform physical examinations of gastrointestinal system.
Practice basic principles of management of nutritional & gastrointestinal disorders.
Discuss preventive measures & prognosis for counseling the patients.
563
transfer, duration of teaching of each content and the mode of assessment
BCQS, SEQS EMQS

DIGITAL LIBRARY
SELF STUDY
TUTORIALS
PRACTICAL
PRACTICAL
LECTURES
SKILL LAB
LIBRARY
OBJECTIVES Subject TOPIC/CONTENT
VIVA
SBL
nt
ANATOMY GIL2 Ang1: Overview 1

structure and function of * *
GIT
Revisit structure and
function of GIT and
Liver
PHYSIOLOGY GIL2 Phy1: Overview 1

secretory, digestive and * *
absorptive function of
GIT
GIL2 Phy2: Overview of 1

motility nervous control * *
and blood circulation of
GIT
ANATOMY GIL2 Ang2: Overview of 1

Blood supply and venous * *
drainage of hepato-
biliary System &
macroscopic &
microscopic structure of
Liver
Elicit relevant history of SURGERY GIL2 Sur1: History taking 1

liver and GI pathology and clinical examination * **
and perform Clinical of abdomen
examination of
abdomen giving SKILL LAB GIL2 Skl1: Abdominal 1.5
emphasis on liver & Examination **
gut. Palpation of Liver &
Spleen
564
SKILL LAB GIL2 Skl2: NG intubation 1.5
**
PAEDRIATICS GIL2 Ped1:Examination GI 1.5

PRACTICAL tract and hepato biliary **
system of children
PATHOLOGY GIL2 Pth1: motor 1
disorders, varices, * *
esophagitis &Baretts
PHARMACOLOGY GIL2 Pha1: Drugs used for 1

dyspepsia (Antacids) & * *
pro-kinetic drugs
MEDICINE GIL2 Med1: GERD, 1
achalasia * *
SURGERY GIL2 Sur2: Surgical 1
Causes, presentation and * *
management of
dysphagia & Ca
esophagus
PATHOLOGY GIL2 Pth2: 1.5

PRACTICAL Histopathology of oral **
cavity, salivary glands &
esophageal disorders
PHARMACOLOGY GIL2 Pha2: Effect of given 1.5

PRACTICAL drug on the intestine **
MEDICINE GIL2 Med2: Esophageal 1
disorders & diagnostic
* *
evaluation for dysphagia
SBL GIL2 SBL1: dysphagia 1.5

*
Describe Acid peptic PATHOLOGY GIL2 Pth3: Pathogenesis 1
disorders pathology of gastritis & peptic ulcer(
* *
and pharmacological, H. Pylori infection)
endoscopic and
laparoscopic
PHARMACOLOGY GIL2 Pha3: Drugs used for 1
management including
acid peptic disorder * *
its complications.
including H pylori
Infection
Antacids & mucosal
Protectives
H2-recptror antagonists
GIL2 Pha4: Drugs used for 1
acid peptic disorder * *
including H pylori
Infection Proton Pump
Inhibitors
565
MEDICINE GIL2 Med3: Dyspepsia, 1
Diagnosis and
* *
management of gastritis/
peptic ulcer disease
SURGERY GIL2 Sur3: Role of Surgery 1

in Acid Peptic Disorder * *
GIL2 Sur4:Diagnosis & 1 *
Management of pyloric *
stenosis/ Ca stomach
PATHOLOGY GIL2 Pth4: histopathology 1.5
PRACTICAL of gastric diseases * **
PHARMACOLOGY GIL2 Pha5: role of 1.5
TUTORIAL antacids in peptic ulcer * *
GIL2 Pha6: management 1.5
of h. pylori * *
GIL2 Pha7: Role of H2 1.5

receptors antagonist in * *
Acid peptic disorder
GIL2 SBL2: Dyspepsia & 1.5

SBL acid peptic disorder *
Identify the causes, PATHOLOGY GIL2 Pth5: malabsorption 1
underlying patho- syndrome (Celiac disease) * *
physiology & describe
the clinical
presentation and
management of acute MEDICINE GIL2 Med4: Causes and 1
and chronic diarrheas, clinical presentation and * *
mal-absorptions, management of
including other lower MALABSORPTION
GI motility disorders SYNDROME/ Celiac
(IBS) and IBD disease
PHARMACOLOGY GIL2 Pha8: General 1 *
management of diarrhea
*
& IBS
MEDICINE GIL2 Med5: Acute 1

gastroenteritis * *
PEDIATRICS GIL2 Ped2: Causes and 1
clinical presentation and * *
management of acute
diarrheas
PATHOLOGY GIL2 Pth6: Inflammatory 1

bowel diseases& * *
diverticulitis
566
MEDICINE GIL2 Med6: Inflammatory 1 *
bowel diseases *
GIL2 Med7: Irritable 1
bowel syndrome * *
PEDIATRICS GIL2 Ped3: Causes and 1
clinical presentation and * *
management of chronic
diarrheas, mal-
absorptions, IBD and
lower GI motility
disorders
PATHOLOGY GIL2 Pth7: Stool D/R & 1.5
PRACTICAL culture *
SURGERY GIL2 Sur5: Clinical 1
presentation and Surgical * *
management of IBD
PHARMACOLOGY GIL2 Pha9: Effect of given 1.5
PRACTICAL drug on the intestine *
PEDIATRICS GIL2 Ped4: Malabsorption 1.5
PRACTICAL **
GIL2 SBL3: Intestinal 1.5
SBL disorder *
GIL2 SBL4: Diarrhea 1.5
*
Identify the causes & PATHOLOGY GIL2 Pth8: Acute 1
describe the underlying appendicitis & diseases of * *
patho-physiology, peritoneal cavity
histopathology, clinical SURGERY GIL2 Sur6: Acute 1
presentation and abdomen & peritonitis * *
management of Acute
and chronic abdomen
GIL2 Sur7: Acute 1 *
pain
Appendicitis *
GIL2 Sur8: Intestinal 1
Obstruction * *
GIL2 Sur9: Management 1
Of Acute & Chronic * *
Pancreatitis
GIL2 Sur10: TB abdomen 1

* *
567
GIL2 Sur11: Colostomy & 1 *
ileostomy *
GIL2 Sur12: Hernias 1 * *
Identify the causes, & PATHOLOGY GIL2 Pth9: Tumors of 1

DISCUSS THE Esophagus * *
underlying patho-
physiology, clinical GIL2 Pth10: Tumors of 1
presentation and stomach * *
principles of
management of weight
loss and abdominal
PRACTICAL Histopathology of * *
mass (GIT and liver
intestinal tumors
malignancies)
PATHOLOGY GIL2 Pth12: Tumors of 1
small intestine * *
GIL2 Pth13: Tumors of 1
large intestine * *
GIL2 Pth14: Tumors of 1
liver * *
GIL2 Pth15: neoplastic 1

disorders of exocrine * *
function of pancreas
SURGERY GIL2 Sur14: Surgical 1

management of Ca
rectum & anal canal
Identify the causes & SURGERY GIL2 Sur14: 1

describe the underlying Hemorrhoids& fissure * *
patho-physiology,
GIL2 Sur15: Perianal 1 *
and management of GI
abscess & fistula-in-ano *
bleed
GIL2 Sur16: Abdominal 1 *

trauma (blunt & *
penetrating)
MEDICINE GIL2 Med8: Diagnosis & 1 *
management of Acute *
Upper GI bleed (non-
variceal&variceal)
Identify the causes & PATHOLOGY GIL2 Pth16: Cirrhosis & 1

describe the underlying portal hypertension * *
patho-physiology,
clinical presentation MEDICINE GIL2 Med9: Cirrhosis, 1
and management of Portal hypertension, * *
ascites Variceal bleed , medical
568
and endoscopic
management
PRACTICAL histopathology of liver * *
diseases
MEDICINE GIL2 Med10: Ascites and 1

concept of SAAG , * *
Hepatic Encephalopathy
&hepato-renal syndrome
PATHOLOGY GIL2 Pth18: General 1

Identify the causes & Features Of Hepatic * *
describe the underlying Disease ( Patterns Of
patho-physiology, Hepatic Injury, Hepatic
clinical presentation Failure, Jaundice
and management of &Cholesteasis )
jaundice
PATHOLOGY GIL2 Pth19: Infectious 1
Disorders Of Liver * *
GIL2 Pth20: Autoimmune 1
Hepatitis, Drug & Toxins * *
Induced Hepatitis &
Metabolic Disorders
GIL2 Pth21: Alcoholic & 1
Non-Alcoholic Hepatitis * *
PHARMACOLOGY GIL2 Pha10: Management 1
Of Hepatitis * *
MEDICINE GIL2 Med11: 1
Management Of Acute * *
Hepatitis & Fulminant
Hepatic Failure
GIL2 Med12: Clinical 1
Presentation And Outline * *
The Management Of
Hepatitis B & C
PAEDRIATICS GIL2 Ped5: Storage & 1

metabolic disorders * *
GIL2 Ped6: Neonatal 1
hyperbilirubinemia, * *
Biliary Atresia
PHARMACOLOGY GIL2 Pha11: Drugs used in 1.5

TUTORIAL management of Hepatitis * *
C
PATHOLOGY GIL2 Pth22: Diagnosis of 1.5
PRACTICAL Hepatitis * *
569
PAEDRIATICS GIL2 Ped7: Management 1.5 *
PRACTICAL Of Neonatal Jaundice *
SURGERY GIL2 Sur17: Presentation 1

& Indication of surgery in * *
liver cirrhosis
PATHOLOGY GIL2 Pth23: Pathology of 1

gallbladder * *
SURGERY GIL2 Sur18: 1

Cholelithiasis& tumors of * *
gallbladder
PATHOLOGY GIL2 Pth24: Non- 1

neoplastic disorders of * *
exocrine function of
pancreas
SURGERY GIL2 Sur19: Management 1
of obstructive jaundice * *
BIOCHEMISTRY GIL2 Bio1: Differentiate 1.5

TUTORIAL between pre-hepatic, * *
Hepatic & post-hepatic
causes of jaundice.
PATHOLOGY GIL2 Pth30: 1.5 *

PRACTICAL histopathology of * *
gallbladder & pancreas
MEDICINE GIL2 Med13: Liver 1 *

abscess & tumors *
SBL GIL2 SBL 5: Jaundice & 1.5
ascites *
Identify the causes & PHARMACOLOGY GIL2 Pha12: Drugs used in 1
describe the underlying constipation * *
patho-physiology,
GIL2 PdS1: Congenital 1
and management of PEDIATRICS and acquired causes & * *
SURGERY management of
constipation
constipation
Identify the causes & PAEDRIATICS GIL2 Ped8: Causes of 1

describe the underlying vomiting, regurgitation / * *
patho-physiology, dysphagia/ in children
GERD
570
clinical presentation PHARMACOLOGY GIL2 Pha13: Emetics and 1
and management of Anti-emetics * *
vomiting.
Recognize the RADIOLOGY GIL2 Rad1: Recognition of 1 *

importance of various normal & abnormal GIT * *
diagnostic measures for Structure
the diagnosis and
MEDICINE GIL2 Med14: diagnostic 1
management of GIT
evaluation of liver *
and liver disorders
disorders
RADIOLOGY GIL2 Rad2: Recognition of 1 *
normal & abnormal GIT * *
Structure
Forensic medicine FORENSIC GIL2 Fmm1: Firearm 1 * *

injuries 1 *
GIL2 Fmm2: Firearm 1 * *
injuries 2 *
GIL2 Fmm3:Metallic 1.5 *

irritants Arsenic, Mercury *
GIL2 Fmm4: RTA and 1 *

Blast Injuries *
GIL2 Fmm5:Metallic 1.5 *
irritants: Copper, Lead *
GIL2 Fmm6: Regional 1 *
injuries: *
Injuries to Head & Skull
Fractures
GIL2 Fmm7: 1 *
Injuries to the brain *
GIL2 Fmm8: non-metallic 1.5 *
irritants: phosphorus *
GIL2 Fmm9: Injuries of 1 *
Neck, Chest, Abdomen, *
Spine and Pelvis
GIL2 Fmm10: Drug of 1.5 *
Addiction- Opium and its *
Derivatives
571
/ GIL2 Fmm 11: 1 *
Environmental Trauma *
Trauma due to Burns,
Heat , cold Electrocution
GIL2 Fmm 12: Drug of 1.5 *

Addiction Cannabis & *
Cocaine and
Amphetamines
GIL2 Fmm13:Trauma due 1 *
to burns *
GIL2 Fmm 14: Deleriants: 1.5 *
Dhatura *
GIL2 Fmm15: Pediatric 1 *
Forensic Medicine *
Infanticide, Battered
Baby Syndrome, Sids
GIL2 Fmm16: Sexual 1 *
Connections Medicolegal *
Aspects
GIL2 Fmm17: Forensic 1 *

Examination of Victim of *
Sexual Assault
GIL2 Fmm18:Medicolegal 1 *
Aspects of Pregnancy , *
Delivery, Abortion
GIL2 Fmm19: Spinal 1.5 *
Poisons Strychnine *
GIL2 Fmm20: Animal 1 *
Poisons: *
Snake Poisoning
GIL2 Fmm21: Cardiac 1.5
Poisons Digitalis, Aconite *
Community medicine COMMUNITY GIL2 Com1: Introduction 1 *
to demography *
GIL2 Com2: Parasitic 1 *
diseases of public health
*
importance
GIL2 Com3: Demography: 1 *

Population Pyramid
*
GIL2 Com4: demography- 1 *
fertility and mortality *
572
Behavioral sciences BEHAVIORAL GIL2 Beh1: Reactions to 1 *
SCIENCES illness
*
GIL2 Beh2:Understanding 1 *
medically unexplained
*
symptoms
GIL2 Beh3: Common 1 *

ethical Omissions in
*
Medical Practice
GIL2 Beh4: Ethical 1 *

dilemmas in a doctors
*
life
573
GASTRO INTESTINAL TRACT AND LIVER-2
TIME TABLE
FIRST WEEK
Days 8:30 to 9:30 9:30 to 10:30 10:30 1:30 1:30-3:00

A- PHARMA: Effect of given drug on the
intestine of rabbit Name of faculty Venue
B- PHYSIOLOGY: Swallowing reflex 1

STUDENTS NOTES: COME
PREPARED PHYSIOLOGY tutorialName of faculty Venue
Overview secretary, C- FORENSIC: Metallic irritants Arsenic,
ANATOMY digestive and absorptive CLINICAL MercuryName of faculty Venue
1 Overview structure and function of GIT POSTING
function of GIT Name of faculty D. PEDIATRICS : Examination GI tract
and hepato biliary system of children
Venue
Name of faculty Venue (Further subgroups in each
E1 UG Lab: Abdominal Examination
Palpation of Liver & Spleen,
E2 SELF-STUDY
PHYSIOLOGY 1. B
NUTRITION
Overview of motility nervous
Balanced diet CLINICAL 2. C
2 control and blood circulation POSTING 3. D
of GIT Name of faculty
4. E
5. A
BIOCHEMISTRYOverview FORENSICMEDICINE
1. C
of Firearm injuries 1 CLINICAL 2. D
3 Dietary carbohydrates & POSTING 3. E
Glycemic index
Name of faculty
Venue 4. A
Name of faculty Venue 5. B
BIOCHEMISTRYOverview 1. D
of BEHAVIORAL
SCIENCES CLINICAL 2. E
Dietary Fats & lipids, in
4 relation to rancidity & per Name of faculty POSTING 3. A
oxidation Venue 4. B
Name of faculty Venue 5. C
BIOCHEMISTRYOverview FORENSIC MEDICINE

of dietary proteins & Firearm injuries-II CLINICAL
5 nitrogen balance Name of faculty POSTING
SURGERY 1. E
History taking and
2. A
NUTRITION clinical examination Clinical
6 ofabdomen 3. B
Nutritional energy balance Posting
Name of faculty Venue Name of faculty 4. C
Venue 5. D
574
GIL 02 MODULE
TIME TABLE WEEK 02 SEMESTER 6
THEME: ESOPHAGEAL DISORDERS
Days 8:30 to 9:30 9:30 to 10:30 10:30 1:30 1:30-3:00

A-PHARMA= Effect of given drug on the intestine
of rabbit(Preparation of Tyrode Solution)Name of
faculty Venue
B-PATHOLOGY: Histopathology of oral cavity,
PATHOLOGY salivary glands & esophageal disordersName of
Ulcero inflammatory
Forensic Medicine
lesions & cancer of oral
faculty Venue
1 RTA and Blast Injuries Clinical Posting C- FORENSIC: Metallic
cavity
Name of faculty Venue Name of faculty irritants:Copper,LeadName of faculty Venue
Venue D= Self Study
E1- SELF STUDY.

E2 UG Lab: Abdominal Examination
Palpation of Liver & Spleen
MEDICINE 1. B
PATHOLOGY GERD, esophagitis, 2. C+E
motor disorders, varices, barretts, hiatus hernia
2 esophagitis &Baretts Clinical Posting 3. D
Name of faculty
Name of faculty Venue 4. -
Venue
5. A
Forensic Medicine 1. C
Pathology
Regional injuries: Tumors of Esophagus 2. D+A
3 Injuries to Head & Skull Clinical Posting 3. E
Fractures Name of faculty
Venue 4. -
5. B
SURGERY 1. D
BEHAVIORAL
Surgical Causes, presentation SCIENCES 2. -
4 and management of dysphagia Clinical Posting 3. A
& Ca esophagus Name of faculty
Venue 4. B+E
5. C
COMMUNITY
PATHOLOGY MEDICINE
Diseases of salivary gland Parasitic diseases of
5 (non-tumors & tumors) public health importance Clinical Posting
Venue
COMMUNITY 1. E
PHARMACOLOGY MEDICINE
Drugs used for dyspepsia Introduction to 2. -
6 (Antacids) & pro-kinetic demography Clinical Posting 3. B
drugs
Name of faculty 4. C+A
Venue 5. D
575
SEMESTER 6 GIL 02 MODULE
TIME TABLE WEEK 03
THEME: STOMACH DISORDERS
Days 8:30 to 9:15 9:15 to 10:00 10:00 to 11:45 11:45 to 1:00

Gp A Pharmacology:= Effect of given
drug on the intestine of rabbit
Gp B Pathology: histopathology of
PHARMACOLOGY gastric diseasesName of faculty Venue
FORENSIC MEDICINE
Injuries to the brain Introduction to Clinical Posting Gp C Forensic Medicine: non-metallic
1
neurotransmitters- I irritants: phosphorusName of faculty
Gp D1 SELF STUDY
D2 UG LAB: NG intubation
Gp E SBL: Dysphagia
PATHOLOGY: 6. B
Pathogenesis of gastritis & PHARMACOLOGY 7. C
2 peptic ulcer( H. Pylori Introduction to Clinical Posting 8. D
infection) neurotransmitters- II
Name of faculty Venue 9. E
10. A
PHARMACOLOGY
Drugs used for acid peptic 6. C
COMMUNITY
disorder including H pylori
MEDICINE 7. D
Infection
3 Demography: Population Clinical Posting 8. E
Antacids & mucosal Pyramid
Protectives 9. A
H2-recptror antagonists 10. B
PHARMACOLOGY 6. D
FORENSIC MEDICINE Drugs usedfor acid peptic 7. E
Injuries of Neck, Chest, disorder including H
4 Clinical Posting 8. A
Abdomen, Spine and Pelvis pylori Infection Proton
Name of faculty Venue Pump Inhibitors 9. B
MEDICINE
Diagnosis and management
of gastritis/ acid peptic PATHOLOGY
5 disease & endoscopic Tumors of stomach Clinical Posting
management of bleeding Name of faculty Venue
peptic ulcer &H.Pylori
PEDIATRICS 6. E
SURGERY 7. A
Causes of vomiting,
Role of Surgery in Acid
6 regurgitation / dysphagia/ Clinical Posting 8. B
Peptic Disorder
in children GERD
10. D
576
TIME TABLE WEEK 04
THEME: Diarrheas & Mal-absorptions
Days 8:30 to 9:15 9:15 to 10:00 10:00 to 11:45 11:45 to 1:00
1.A=Pharmacology: role of antacids in

peptic ulcer tutorialName of faculty
Venue
2.B=Pathology: STOOL D/R & CULTURE
MEDICINE
PATHOLOGY Causes and clinical presentation and Name of faculty Venue
MALABSORPTION management of 3.C= Forensic Medicine: Drug of
1 SYNDROME (Celiac disease) MALABSORPTION SYNDROME/ Clinical Posting
Celiac disease
Addiction- Opium and its Derivatives
4. D2= UG Lab: NG intubation=
D1= SELF STUDY
5. E=SBL: Dyspepsia and acid peptic
disorders
MICROBIOLOGY 1. B
PATHOLOGY Infective agents of dysentery & 2. C
2 enterocolitis& ischemic colitis diarrhea Clinical Posting 3. D
Name of faculty Venue Name of faculty Venue 4. E
5. A
1. C
PHARMACOLOGY 2. D
MEDICINE
3 Emetics and Anti-emetics Acute gastroenteritis Clinical Posting 3. E
Name of faculty Venue Name of faculty Venue 4. A
5. B
1. D
PEDIATRICS 2. E
Causes and clinical presentation
and management of acute 3. A
4 PATHOLOGY Clinical Posting
diarrheas Inflammatory bowel diseases 4. B
Name of faculty Venue Name of faculty Venue 5. C
FORENSIC MEDICINE
MEDICINE Environmental Trauma
5 Inflammatory bowel diseases Trauma due to Burns, Heat , cold Clinical Posting
Name of faculty Venue Electrocution
PEDIATRICS 1. E
Causes and clinical presentation
MEDICINE 2. A
and management of chronic
6 Irritable bowel syndrome Clinical Posting 3. B
diarrheas, mal-absorptions, IBD
and lower GI motility disorders Name of faculty Venue 4. C
Name of faculty Venue 5. D
577
SEMESTER 6 GIL02 MODULE
TIME TABLE WEEK 05
THEME: INTESTINAL DISORDERS
Days 8:30 TO 9:15 9:15 TO 10:00 10:00 TO 11:45 11:45 TO 1:00

1.A= Pharmacology Tutorial: Role of
H2 receptors antagonist in Acid peptic
disorderName of faculty Venue
2.B= Pathology Histopathology of
intestinal tumors
COMMUNITY Name of faculty Venue
PATHOLOGY MEDICINE
1 ACUTE ABDOMEN Clinical Posting 3.C= Forensic Medicine: Drug of
Introduction to
Name of faculty Addiction Cannabis & Cocaine and
demography-III
Venue AmphetaminesName of faculty
Venue
4.D=Pediatrics: GI
Course(Malabsorption)
5.E= SBL
PATHOLOGY SURGERY 1. B
Tumors of small & large Acute abdomen & 2. C
2 intestine lecture-I peritonitis Clinical Posting 3. D
Name of faculty Name of faculty Venue 4. E
Venue
5. A
PATHOLOGY SURGERY 1. C
Tumors of small & large Clinical presentation 2. D
3 intestine lecture II and Surgical Clinical Posting 3. E
Name of faculty management of IBD 4. A
Venue Name of faculty Venue 5. B
1. D
SURGERY 2. E
Intestinal Obstruction FORENSICMEDICINE
4 Trauma due to burns Clinical Posting 3. A
Name of faculty
Venue 4. B
5. C
PHARMACOLOGY
Drugs used in B.S
5 constipation Functional bowel disorders Clinical Posting
Venue
PEDIATRICS
SURGERY 1. E
PHARMACOLOGY
Congenital and acquired 2. A
6 causes & management of
General management of Clinical Posting 3. B
constipation diarrhea & IBS
Name of faculty
Venue 5. D
578
GIL 02 MODULE
TIME TABLE WEEK 06 SEMESTER-VI
THEME: LIVER DISORDERS
Days 8:30 to 9:15 9:15 to 10:00 10:00 12:00 12:00 to 1:30

A= Pharmacology TUTORIAL
management of h. pyloriName of faculty
ANATOMY Venue
Overview of Blood supply and BIOCHEMISTRY B= Pathology histopathology of liver
venous drainage of hepato- Overview of bio-molecular diseasesName of faculty Venue
1 Clinical Posting
biliary System & macroscopic function of Liver
& microscopic structure of Liver Name of faculty Venue C= Forensic Medicine Deleriants:
Name of faculty Venue DhaturaName of faculty Venue
D= SBL(MEDICAL WARDS)
PATHOLOGY:
General Features Of Hepatic FORENSIC
1. B
Disease ( Patterns Of Hepatic Pediatric Forensic Medicine
2. C
2 Injury, Hepatic Failure, Infanticide, Battered Baby Clinical Posting
3. D
Jaundice &Cholesteasis ) Syndrome, Sids
4. A
1. C
PATHOLOGY: PHARMACOLOGY
Infectious Disorders Of Liver Management Of Hepatitis 2. D
3 Clinical Posting
Name of faculty Venue Name of faculty Venue 3. A
4. B
PATHOLOGY
MEDICINE
Autoimmune Hepatitis, Drug
Management Of Acute
4 & Toxins Induced Hepatitis & Clinical Posting
Hepatitis & Fulminant
Metabolic Disorders
Hepatic Failure
1. D
MEDICINE 2. A
PATHOLOGY:
Clinical Presentation And 3. B
Alcholic& Non-Alcholic
5 Outline The Management Of Clinical Posting
(Nash) 4. C
Hepatitis B & C
579
SEMESTER 6GIL 02 MODULE
TIME TABLEWEEK 07
Days 8:30 to 9:30 9:30 to 10:00 10:30 1:00 1:30-3:00
FORENSIC MEDICINE
1 Sexual Connections SELF STUDY Clinical Posting SELF STUDY
Medicolegal Aspects
FORENSIC MEDICINE
2 Forensic Examination of SELF STUDY Clinical Posting
Victim of Sexual Assault
RADIOLOGY
3 SELF STUDY Recognition of normal & Clinical Posting SELF STUDY
abnormal GIT Structure
580
TIME TABLEWEEK 08
Theme: LIVER-CIRRHOSIS
Days 8:30 to 9:30 9:30 to 10:30 10:30 1:30 1:30-3:00

1. A= PHARMA: Effect of given drug on
the intestine of rabbit Name of
faculty Venue
FORENSIC 2. B= Pathology laboratory Diagnosis
MEDICINE of Hepatitis Practical
PATHOLOGY Name of faculty Venue
Medicolegal Aspects of
Cirrhosis & portal
1 Pregnancy , Delivery, Clinical Posting 3. C= Forensic Medicine: Spinal Poisons
hypertension
Abortion
Name of faculty Strychnine Name of faculty Venue
Name of faculty
Venue 4. D(D1, D2, D3)= Paeds: Management
Venue
Of Neonatal Jaundice Name of faculty
Venue
5. E= SBL: Name of faculty Venue
MEDICINE
Cirrhosis, Portal 1. B
PATHOLOGY
hypertension, Variceal 2. C
Circulatory disorders of
2 bleed , medical and Clinical Posting 3. D
liver
endoscopic management
Name of faculty 4. E= (E1, E2, E3)
Name of faculty
Venue 5. A
Venue
MEDICINE
Ascites and concept of 1. C
PATHOLOGY
SAAG , Hepatic 2. D
Tumors of liver
3 Encephalopathy Clinical Posting 3. E
&hepato-renal syndrome Name of faculty
Venue 4. A= (A1, A2, A3)
Name of faculty
Venue 5. B
PEDIATRICS
Storage & metabolic
disorders 1. D
Acute hepatitis (A, E)/ 2. E
4 Fulminant hepatic SELF STUDY Clinical Posting 3. A
Failure 4. B (B1, B2, B3)
5. C
Name of faculty
Venue
PEDIATRICS:
Neonatal PHARMACOLOGY
hyperbilirubinemia, Drugs used in IBD
5 Biliary Atresia Clinical Posting
Name of faculty
Venue
SURGERY FORENSIC 1. E
Presentation & Indication MEDICINE
2. A
of surgery inliver Animal Poisons:
6 cirrhosis Clinical Posting 3. B
Snake Poisoning
Name of faculty Name of faculty 4. C (C1, C2,C3)
Venue Venue 5. D
NOTE: The practical groups for Pediatrics class are divided into three sub groups. The details of each group are
available on the DUHS website.
581
TIME TABLEWEEK 09
THEME: PANCREAS & GALLBLADDER DISORDERS
Days 8:30 to 9:30 9:30 to 10:30 10:30 1:30 1:30-3:00

1.A= PHARMA-TUTORIAL: Drugs
used in management of Hepatitis C.
2.B= PATHOLOGY
PRACTICAL:histopathology of
gallbladder & pancreas Name of faculty
Venue
PHARMACOLOGY
Drugs Used In PATHOLOGY 3.C= FORENSIC MEDICINE: Cardiac
Amebiasis Pathology of gallbladder CLINICAL Poisons Digitalis, Aconite
1
POSTING Name of faculty Venue
Venue 4. D(D1, D2, D3) PAEDS=Assesment
of nutritional status Name of faculty
Venue
5.E= BIOCHEM-TUTORIAL:
Differentiate between pre-hepatic,
Hepatic & post-hepatic causes of
jaundice. Name of faculty Venue
NUTRITION 6. B
Assessment of SURGERY 7. C
2 nutritional status Cholelithiasis CLINICAL
8. D
Name of faculty Venue POSTING
Name of faculty 9. E= (E1, E2, E3)
Venue 10. A
PATHOLOGY 6. C
Non-neoplastic NUTRITION 7. D
disorders of exocrine Nutrition care plan CLINICAL
3 development & nutrition 8. E
function of pancreas POSTING
Name of faculty toxicology 9. A= (A1, A2, A3)
Venue Name of faculty Venue 10. B
PATHOLOGY
SURGERY 6. D
neoplastic disorders of
Management of obstructive 7. E
exocrine function of CLINICAL
4 jaundice 8. A
pancreas POSTING
9. B (B1, B2, B3)
Name of faculty Name of faculty Venue 10. C
Venue
RADIOLOGY
Recognition of normal SURGERY
& abnormal Management Of Acute & CLINICAL
5 Chronic Pancreatitis
hepatobiliary structures POSTING
Venue
NUTRITION SURGERY 6. E
Medical nutrition Indication And Surgical 7. A
therapy CLINICAL
6 Management of 8. B
POSTING
Name of faculty Hemorrhoids 9. C (C1, C2,C3)
Venu Name of faculty Venue 10. D
NOTE The practical groups for Pediatrics class are divided into three sub groups. The detail of each group is available on the
DUHS website
582
LEARNING OBJECTIVES
By the end of the lecture, the student should be able to:
ANATOMY
GIL2 Ang1: Overview structure and function of GIT
Recall the functional significance of the gastrointestinal system

Describe the structure of the gastrointestinal tract, the glands that drain
into it, and its subdivision.
List the major gastrointestinal secretions.
Identify the major hormones of the gastrointestinal system
GIL2 Ang2: Overview of blood supply and venous drainage of hepato-biliary

system & macroscopic & microscopic structure of liver
Recall Blood circulation of hepato-biliary system

Describe macroscopic & microscopic structure of liver
PHYSIOLOGY
GIL2 Phy1: Overview secretary, digestive and absorptive function of GIT
Recall Mechanism of digestion of macro & micro nutrients
Recall Mechanism of absorption of nutrients and water
GIL2 Phy2: Overview of motility & nervous control & circulation of GIT
Recall principles of GIT nervous control of secretion & motility regulation

Recall Blood circulation of GIT system
583
BEHAVIORAL SCIENCES
GIL2 Beh1: Reactions to illness
GIL2 Beh2: Understanding medically unexplained symptoms
GIL2 Beh3: Common ethical Omissions in Medical Practice
Describe the importance of Informed consent and confidentiality

Describe the procedure of taking informed consent and maintaining
confidentiality
Apply given concepts in different clinical setting and different settings
related to Medical students.
GIL2 Beh4: Ethical dilemmas in a doctors life
Describe the concept of different ethical dilemmas in a life of doctors

particularly in relation to Accepting gifts from patients, Sexual boundaries
violation etc.
Describe the issues of charging fee from Patients, colleagues teachers,
medical students
Describe the concepts of E-consultations, relationship with media.
Discuss important issues in context to relationship with pharmaceutical
industry Recognize rights and responsibilities of patients
PEDRIATICS SURGERY
GIL2 Pds1: Congenital and acquired causes & management of constipation
List the causes of congenital & acquired constipation.

Explain the pathogenesis, clinical presentation, laboratory evaluation of
constipation.
Describe the surgical management of constipation in paedriatic patient
584
MEDICINE
GIL2 Med1: GERD, achalasia
Recall overview of Anatomy and Physiology of Esophagus

List the common esophageal disorders
Explain the clinical picture and presentation of GERD, Reflux Esophagitis,
Hiatus hernia and Barrett esophagus.
GIL2 Med2: Esophageal disorders & diagnostic evaluation for dysphagia
Explain causes, pathogenesis & clinical presentation of esophageal

disorders
Explain diagnostic evaluation techniques of dysphagia
GIL2 Med3: Dyspepsia, diagnosis and management of gastritis/ peptic ulcer

disease
Explain the causes, clinical presentation, diagnostic tests &management of

gastritis & acid peptic disease
GIL2 Med4:Malabsorption Syndrome

Explain the causes, clinical presentation & management of malabsorption
syndrome including chronic pancreatitis, celiac sprue,Whipples disease,
lactase deficiency, bacterial overgrowth
Describe tests of malabsorption
GIL2 Med5:acute gastroenteritis

Explain types, risk factors, causes, investigative approach and treatment of
acute gastroenteritis
585
GIL2 Med6:inflammatory bowel disease
Explain clinical presentation, microscopic & macroscopic features
Describe investigation & management of Ulcerative colitis &Crohns disease
GIL2 Med7:Irritable Bowel Syndrome

Define & classify IBS
Explain clinical presentation, diagnostic criteria & treatment options for IBS
GIL2 Med8: Diagnosis & management of acute upper GI bleed (non-

variceal&variceal)
Explain causes, pathogenesis, differential diagnosis & clinical presentation

of acute upper GI bleed
Interpret diagnostic evaluation techniques & management
Explain complications of acute upper GI bleed & its management
GIL2 Med9:Cirrhosis, portal hypertension, variceal bleeding management
Discuss causes, clinical presentation, complications of cirrhosis, Portal

hypertension & Gastro esophageal varices
Explain pharmacologic & endoscopic management of variceal bleed
GIL2 Med10:ascites& concept of SAAG, hepatic encephalopathy &hepato-renal

syndrome
Describe the causes, clinical examination of ascites and concepts of SAAG

(serum ascites albumin gradient)
Explain the causes, clinical presentation, and management of Hepatic
encephalopathy &Hepato renal syndrome.
GIL2 Med11: Management of acute hepatitis & fulminant hepatic failure
Describe acute on chronic liver failure

give classification of acute liver failure
discuss drugs that can cause fulminant hepatic failure
Explain grades, clinical presentation & management of hepatic
encephalopathy&hepato-renal syndrome
586
GIL2 Med12:Clinical presentation and outline the management of hepatitis B & C
Discuss causes, clinical presentation, complications of Hepatitis B & C

Explain pharmacologic management of Hepatitis B & C
GIL2 Med13: Liver abscess & tumors
Explain causes, pathogenesis, differential diagnosis, complications& clinical

presentation of liver abscess
Describe investigative approach and treatment of liver abscess
Explain types, pathogenesis, grades, complications& clinical presentation of
liver tumors
Interpret diagnostic evaluation techniques & management of liver tumors
GIL2 Med14: Diagnostic evaluation of liver disorders
List methods of evaluation of liver disorders

explain & evaluate the laboratory diagnostic tests done in hepatic diseases
explain & evaluate the interventional diagnostic tests done in hepatic
diseases
PEDRIATICS
GIL2 Ped2: Causes and clinical presentation and management of acute diarrheas
List the causes of acute diarrhea.

Explain the pathogenesis & clinical presentation of acute diarrhea.
Describe the laboratory evaluation of acute diarrhea.
GIL2 Ped3: Causes and clinical presentation and management of chronic

diarrheas, mal-absorptions, IBD and lower GI motility disorders
List the causes of chronic diarrhea.

Explain the pathogenesis of chronic diarrhea.
Describe the laboratory evaluation of chronic diarrhea.
587
GIL2 Ped5: Storage & metabolic disorders
Explain causes of storage & metabolic disorders in paedriatic population

Describe clinical presentationof storage & metabolic disorders in paedriatic
population
Explain lab diagnosis of storage & metabolic disorders in paedriatic
population
describe treatment of storage & metabolic disorders in paedriatic
population
GIL2 Ped6: neonatal hyperbilirubinemia
Explain clinical presentation of Biliary atresia, Hyper-

bilirubinemia&Neonatal cholestasis
Describe lab diagnosis, treatment of Biliary atresia, Hyper-
bilirubinemia&Neonatal cholestasis
GIL2 Ped8: Causes of vomiting/ dysphagia in children & GERD
List causes of vomiting & dysphagia in children

Explain clinical presentation, examination, diagnostic tests and treatment
of GERD in children
COMMUNITY MEDICINE
GIL2 Com1: Introduction to demography-I
Define demography
Describe features & uses of population pyramid
Describe profiles of Population Pyramid namely Rapid growth, Slow
Growth, Zero Growth
GIL2 Com2: Parasitic diseases of public health importance

Define medical parasitology, parasitism
Describe parasites of medical importance.
Explain Modes of parasitic infection their prevention and control.
588
GIL2 Com3: Demography: Population Pyramid
Define age & population pyramid

Explain features &uses of a population pyramid.
Discuss three general profiles of age-sex composition.
Explain Rapid growth, Slow growth, Zero growth
GIL2 Com4: Demography- fertility and mortality
Define fertility & fecundity

Interpret measures of fertility namely Crude Birth Rate , Age-specific
Fertility Rate, Total Fertility Rate
Explain cohort measures of fertility
Define mortality & give causes of rapid mortality decline
Define and explain Crude Death Rate , Age-specific Death Rate, Maternal
Mortality Ratio, Infant Mortality Rate
Describe direct & indirect standardization
FORENSIC MEDICINE
GIL2 Fmm1: Firearm injuries
Give definition & types of ballistics

Classify firearm weapons
List parts of a firearm weapon
Explain cartridges of various firearms
Utilize the above knowledge for better understanding of various aspects of
interpretation of firearm injuries clinically.
GIL2 Fmm2: Firearm injuries
Give definition & types of ballistics

Classify firearm weapons
List parts of a firearm weapon
Explain cartridges of various firearms
Utilize the above knowledge for better understanding of various aspects of
interpretation of firearm injuries clinically.
589
GIL2 Fmm4: road traffic accidents & bomb blast injuries
List causes of road traffic accidents

Learn motor vehicle ordinance 1965 which should be known to a doctor
examining a person for vehicle license
Understand types of injuries in road traffic accidents to pedestrians, driver,
occupants of vehicle
Understand safety measures in new vehicles.
Evaluate blast injuries & types of injuries caused by blasts
List types of bombs
Explain mechanism of action of blast waves
Interpret postmortem in cases of bomb blasts
GIL2 Fmm6: Regional injuries-head injuries, skull fractures and intracranial

hemorrhages
Discuss head injuries including soft tissue injuries such as scalp

discuss types of fractures of skull & mechanism of their production
explain various types of intracranial hemorrhages and signs to diagnose
them
evaluate age of hemorrhage.
GIL2 Fmm7: Injuries to the brain
Explain the mechanism of brain injuries, types of brain injuries with special
reference to terms such as:
Accelerating injury
Decelerating injury
Shear strain/ rotational injury
Coup&contre coup injury along with various theories about these injuries
GIL2 Fmm9: Injuries of neck, chest, abdomen, spine and pelvis
Explain Injuries to spine with special stress on injuries to cervical spine as

seen in hanging, strangulation, throttling.
Give definition and idea about railway spine
590
Evaluate characteristic features of suicidal and homicidal cut throat, injuries
to neck structures of medicolegal significance.
Describe chest injuries such as fractures of ribs, pneumothorax,
haemothorax, traumatic asphyxia, cardiac tamponade, stab wounds of
heart.
Explain abdominal injuries such as rupture of internal organs in medicolegal
cases.
Explain injuries to pelvis with stress on pelvic fractures
GIL2 Fmm11: Environmental trauma-Trauma due to heat, cold electrocution
Explain pathophysiology, clinical presentation & postmortem findings of

injuries due to cold, heat & electrocution
GIL2 Fmm13: trauma due to burns
Define burns
Classify types of burns
Explain complications of burns
GIL2 Fmm15:Lecture on infanticide, battered baby syndrome, sudden infant

death syndrome
Define infanticide, feticide, still born baby, dead born body, maceration
describe fetal age estimation
explain signs of live birth, precipitate labor/ unconscious delivery
evaluate criminal causes of death of new born babies
Explain autopsy on bodies of new born dead bodies
discuss child abuse i.e. Battered baby syndrome, sudden infant death
syndrome and its medicolegal aspects.
591
GIL2 Fmm16: Sexual connections medicolegal aspects
List& define natural & unnatural causes of sexual offence

Definelaws relevant to sexual intercourseaccording to zina&hadood
ordinance of Pakistan Penal Code
GIL2 Fmm17: Forensic examination of victim of sexual assault
Give steps of evaluating sexual assault victim

Explain steps of taking detailed history, clinical examination, laboratory
specimens, consent of rape victim
GIL2 Fmm18: Medicolegal aspects of pregnancy, delivery, abortion
Define Nageles rule for birth date estimation
Explain the fetal growth period during pregnancy and its medicolegal
aspect regarding pregnancy, delivery & abortion
GIL2 Fmm20: Snake Poisoning
Describe clinical presentation & lab diagnosis of snake bites

Explain types & composition of venoms
Evaluate use and contraindication of anti-venom
RADIOLOGY
GIL2 Rad1: Recognition of normal & abnormal GIT Structure
Explain the diagnostic tests for GIT evaluation

Interpret abnormal results of GIT diagnostic tests
592
GIL2 Rad2: Recognition of normal & abnormal hepato-biliary structure
Explain the diagnostic tests for hepato-biliary evaluation
Identify the normal hepato-biliary diagnostic tests
Interpret abnormal results ofhepato-biliary diagnostic tests
PATHOLOGY
GIL2 Pth1: Motor disorders of esophagus, varices, esophagitis & Barretts

esophagus
Explain etiology of motor disorders of esophagus, esophageal varices,

esophagitis & Barretts esophagus
morphology & pathogenesis of motor disorders of esophagus, esophageal
varices, esophagitis & Barretts esophagus
GIL2 Pth3: Pathogenesis of gastritis & peptic ulcer (H. Pylori infection)
Explain the clinical presentations of gastritis & peptic ulcers

Describe etiologies and pathogenesis, gross and microscopic changes found
in gastritis & peptic ulcers
GIL2 Pth5: Malabsorption Syndrome
Explain the clinical presentations of different malabsorption syndromes

Describe etiologies, pathogenesis, and gross and microscopic changes
found in different malabsorption syndromes
GIL2 Pth6: Inflammatory Bowel Disease
Explain etiologiesof inflammatory bowel disease including Crohns disease

and ulcerative colitis
Explain pathogenesis, gross and microscopic changes of inflammatory
bowel disease including Crohns disease and ulcerative colitis
describe clinical presentations of inflammatory bowel disease including
Crohns disease and ulcerative colitis
593
GIL2 Pth8: Acute appendicitis & diseases of peritoneal cavity
Describe the clinical presentations of intestinal obstruction, acute

appendicitis, diverticulitis & hemorrhoids
Describe etiologies, pathogenesis, and gross and microscopic changes
found in intestinal obstruction, acute appendicitis, diverticulitis &
hemorrhoids
GIL2 Pth9: tumor of esophagus
explain etiology of pre-neoplastic & neoplastic conditions of esophagus

describe morphology & pathogenesis of pre-neoplastic & neoplastic
conditions of esophagus
GIL2 Pth10: Neoplasms of stomach
Explain etiology of neoplastic conditions of stomach & common gastric

polyps.
Describe morphology & pathogenesis of neoplastic conditions of stomach &
common gastric polyps.
GIL2 Pth12: malignant lesions of small intestine
Explain etiology of neoplastic conditions of small intestine

Describe morphology & pathogenesis of neoplastic conditions of small
intestine
GIL2 Pth13: malignant lesions of large intestine
Explain etiology of neoplastic conditions of large intestine

morphology & pathogenesis of neoplastic conditions of large intestine
GIL2 Pth14: Tumors of liver
Explain etiologyof hepatic tumors
Describe morphology & pathogenesis of hepatic tumors
594
GIL2 Pth15: neoplastic disorders of exocrine function of pancreas
Explain etiology of neoplastic conditions of exocrine pancreas

Describe morphology & pathogenesis of neoplastic conditions of exocrine
pancreas
GIL2 Pth16: Cirrhosis & portal hypertension
Explain etiology of cirrhosis & portal hypertension

Describe morphology & pathogenesis of cirrhosis & portal hypertension
GIL2 Pth18: General features of hepatic disease (patterns of hepatic injury,

hepatic failure, jaundice &cholesteasis)
Explain causes of hepatic injury, hepatic failure, hepato-renal syndrome

&hepato-pulmonary syndrome
Describe etiology, pathogenesis of hepatic injury, hepatic failure, hepato-
renal syndrome &hepato-pulmonary syndrome
describe clinical diagnosis of hepatic injury, hepatic failure, hepato-renal
syndrome &hepato-pulmonary syndrome
GIL2 Pth19: infectious disorders of liver
Explain etiology, of Hepatitis virus A, Hepatitis virus B, Hepatitis virus C,

Hepatitis virus D, Hepatitis virus E.
Describe pathogenesis, mode of transmission of ofHepatitis virus A,
Hepatitis virus B, Hepatitis virus C, Hepatitis virus D, Hepatitis virus E.
Describe clinical diagnosis of Hepatitis virus A, Hepatitis virus B, Hepatitis
virus C, Hepatitis virus D, Hepatitis virus E.
595
GIL2 Pth20: Autoimmune hepatitis, drug & toxins induced hepatitis & metabolic
disorders
Explain etiology, morphology & pathogenesis ofautoimmune hepatitis

&metabolic disorders
Explain etiology, morphology & pathogenesis & causative agents ofdrug &
toxins induced hepatitis
GIL2 Pth21: Alcoholic & non-alcoholic hepatitis
Explain etiology, morphology, grading, pathogenesis &clinical features of

alcoholic steatohepatitis& non-alcoholic steatohepatitis.
Explain etiology, morphology, grading, pathogenesis &clinical features of
acute fatty liver &intrahepatic cholestasis of pregnancy.
GIL2 Pth23: Diseases of the gall bladder
Describe the congenital anomalies of the gall bladder

Explain morphology, pathogenesis of cholelithisiasis
Describe morphology, gross & microscopic histopathology of acute
cholecystitis& chronic cholecystitis
Explain morphology, pathogenesis of biliary atresia
Discuss etiology, morphology, pathogenesis, gross &histopathological
presentation of tumors of the gall bladder
GIL2 Pth24: Non-neoplastic disorders of exocrine function of pancreas
Explain etiology ofCongenital anomalies& outcome of pancreatic

inflammations
Describe morphology & pathogenesis ofCongenital anomalies& outcome of
pancreatic inflammations
596
SURGERY
GIL2 Sur1: History taking and clinical examination of abdomen
Take detailed history of patient with abdominal complaints

Perform clinical examination of abdomen and liver
GIL2 Sur2: Surgical causes, presentation and management of dysphagia & ca

esophagus
Explain causes, pathogenesis& clinical presentation of dysphagia&Ca

esophagus
Understand diagnostic evaluation techniques & surgical intervention
Explain complications of surgical intervention
GIL2 Sur3: Role of surgery in acid peptic disease

Explain causes & pathogenesis of gastritis, duodenal ulcers & gastric ulcers
Understand diagnostic evaluation techniques & surgical intervention of
peptic ulcers
GIL2 Sur4: Diagnosis & management of pyloric stenosis/ Ca stomach
Explain causes, pathogenesis& clinical presentation of pyloric stenosis&Ca

stomach
Understand diagnostic evaluation techniques & surgical intervention
GIL2 Sur5: Clinical presentation and surgical management of Inflammatory

bowel disease
Define spectrum of inflammatory bowel disease

Explain clinical manifestations of ulcerative colitis &Crohns disease
Compare distinguishing features between UC and CD
Discuss diagnostic approach, complications &management of IBD
597
GIL2 Sur6: Acute abdomen & peritonitis
Describe causes, clinical presentation, diagnostic tests, management &

complications of acute abdomen

complications of peritonitis
GIL2 Sur7: Acute appendicitis
Describe causes, clinical presentation of acute appendicitis
diagnostic tests, management & complications of acute appendicitis
GIL2 Sur8: Intestinal obstruction
Describe causes, clinical presentation of intestinal obstruction
Describe diagnostic tests, management & complications of intestinal

obstruction
GIL2 Sur9: Management of Acute & Chronic Pancreatitis
Describe causes, clinical presentation of acute & chronic pancreatitis

Describe diagnostic tests, management & complications of acute & chronic
pancreatitis
GIL2 Sur10: Tb abdomen
Describe clinical presentation, diagnostic tests, management &

complications of abdominal tuberculosis
Explain the pathogenesis of tuberculosis organism
GIL2 Sur11: Colostomy & ileostomy
define colostomy & ileostomy

explain the procedure of colostomy & ileostomy
evaluate colostomy & ileostomy as surgical management
describe complications of colostomy & ileostomy
598
GIL2 Sur12: Hernias

complications of abdominal hernias
GIL2 Sur13: Surgical management of Ca rectum & anal canal
Describe causes, clinical presentation of rectal & anal canal malignancies
Explain diagnostic tests, management & complications of rectal & anal

canal malignancies
GIL2 Sur14: Hemorrhoids & fissure
Evaluate clinical presentation of hemorrhoids and fissure

Describe complications, indication for surgical intervention in hemorrhoids
bleeding
GIL2 Sur15: Perianal abscess & fistula-in-ano
Describe the causes, clinical presentationof perianal abscess & fistula-in-

ano
Describe diagnostic measures, management & complications of perianal

abscess & fistula-in-ano
GIL2 Sur16: Abdominal trauma (blunt & penetrating)

Evaluate types, clinical presentation of abdominal trauma
Describe investigative approach, complications, indication for surgical

intervention in abdominal trauma
GIL2 Sur17: Presentation & indication of surgery in liver cirrhosis
Describe the causes, clinical presentation of liver cirrhosis
Describe indications for surgical management & complications of liver

cirrhosis
599
GIL2 Sur18: Cholelithiasis&tumors of gallbladder
Describe the causes, clinical presentation of gallstones & tumors of

gallbladder
Describe management & complications of gallstones & tumors of
gallbladder
GIL2 Sur19: Management of obstructive jaundice & pancreatitis problems
Describe the causes, clinical presentation of obstructive jaundice &

pancreatitis disorders
Describe management & complications of obstructive jaundice
PHARMACOLOGY
GIL2 Pha1: Drugs used for dyspepsia & pro-kinetic drugs
Describe mechanism of action, types, indications & side effects of systemic

antacids & non systemic antacids
Describe Mechanism of action, types, indications & side effects of pro-
kinetic agents
GIL2 Pha3: Treatment of acid peptic disorder & h. Pylori infection
Explain mechanism of action, indication and side effects of Mucosal

protective agents, Sucralfate, Misoprostol & colloidal bismuth compounds
Explain mechanism of action, types, indications & side effects of H2
GIL2 Pha4: drugs used for peptic disorder including H. Pylori infection
(proton pump inhibitors)
Discuss treatments of peptic ulcer

Explain mechanism of action, types, indications & side effects of PPI
receptor antagonists & Proton pump inhibitors
explain Triple & quadruple therapy
600
GIL2 Pha8: General Management of diarrhea & IBS
Describe mechanism of action, side effects, adverse effects of pharmacological
management of diarrheas, Ulcerative colitis, Crohns disease ,
Diverticulitis&Irritable bowel syndrome
GIL2 Pha10: Management of Hepatitis
Describe mechanism of action of drugs used in management of hepatitis &

related complications
Give typesof drugs used in management of hepatitis
Explain side effects& adverse effects of drugs used in management of
hepatitis & related complications
GIL2 Pha12: Pharmacology-Drugs used in constipation
Describe types &mechanism of action of drugs used in constipation

Explain side effects& adverse effects of drugs used in constipation
GIL2 Pha13: Pharmacology-Anti-Emetic Drugs
explain the physiology basis of vomiting and the pharmacological basis of

anti-emetic drugs
Describe the pharmacodynamics and pharmacokinetics of dopamine
antagonists, Anti-cholinergic agents, serotonin antagonists, Anti-histamines
and steroids
Critically appraise the clinical usage of these drugs
601
GIT & Liver Module:
III. Introduction To History taken and Abdominal Examination

Diseases of gastrointestinal system are one of the common causes of morbidity and mortality
both in adults and children Abdominal examination is performed as an integral part of physical
examination, or when a patient presents with gastro intestinal problems (for example: Abdominal
pain, nausea, vomiting, diarrhea and GI bleeding ).
At the end of the session students should be able to:-
Enumerate the steps of examination of Abdomen.
To demonstrate correct technique of auscultation of Gut sounds.
SCENERIO BASE LEARNING

GIL2 Sbl 1
Define of peptic ulcer disease.
Enlists types of peptic ulcer disease
Describe relevant diagnostic workup of peptic ulcer disease.
Management of peptic ulcer disease
GIL2 Sbl 2
Define of diarrhea
Enlists causes of diarrhea
Describe relevant investigations of diarrhea
Discuss management of diarrhea
GIL2 Sbl 3
Recognize a patient of Hepatitis B positive
Discuss its complications
Discuss the relevant investigations and its management
GIL2 Sbl 4
Define of dysphagia
Enlist the causes of dysphagia
Enumerate differential diagnosis of dysphagia
Discuss relevant diagnostic workup and management of dysphagia
602
ROUND
WEEKS/HOURS 1 2 3 4 5 6 7 8 T1 T1x100/T2
OFF
ANATOMY 1 - - - - 1 - - 2 1.33 1
BIOCHEMISTRY - - - - - - - 1.5 1.5 1.00 1
PHYSIOLOGY 2 - - - - - - - 2 1.33 1
PATHOLOGY 3.5 3.5 3.5 4.5 1.5 5.5 3.5 4.5 30 20.06 20
PHARMA 2.5 3.5 2.5 2.5 1.5 2.5 1.5 1.5 18 12.04 12
FORENSIC MED. 2.5 2.5 3.5 2.5 5.5 4.5 3.5 1.5 26 17.39 17
BEHAVIORAL
1 1 - 1 - - 1 - 4 2.67 3
SCIENCES
COMMUNITY
- 1 - - 1 - 1 1 4 2.67 3
MEDICINE
SURGERY 2 2 2 5 5 - 1 3 20 13.37 13
MEDICINE 2 2 2 1 1 3 3 - 14 9.36 10
PEDRIATICS 1.5 2.5 2 - 1.5 1.5 3.5 1.5 14 9.36 10
PAEDS.
- - - - 1 - - - 1 0.66 1
SURGERY
1
RADIOLOGY - - 1 - - - - 1 2 1.33
SKILL LAB 1.5 1.5 1.5 1.5 - - - - 3 2.00 2
SBL - - 1.5 1.5 1.5 1.5 1.5 - 7.5 5.01 5
TOTAL 18 19.5 19.5 19.5 19.5 18.5 19.5 15.5 149.5 100 100
603
GI AND LIVER-2 MODULE
(SEMESTER-VI)
THEORY

SEMESTER
ATP 25
EXAM
PAPER-I 80%
One best Questions
20
based on CBL
Total 100
MODULE EXAM
EMQs 10
ATP 20
MODULE PAPER 20%
One best Questions
20
based on CBL
Total 100
STRUCTURED VIVA

SUMMATIVE
ASSESMEN
SEMESTER
EXAM
See Semester
PAPER- I - A Structured viva
T
Assessment Plan
ASSESSMENT TOOLS
Structured Feedback
Facilitator
NOTE: Paper II & IV- B of Semester-6 Examination are Based on Renal -2 Module.
Paper III & IV-C of Semester-6 Examination are Based on Endocrinology-2 Module.
604
CREDIT HOURS
SEMESTER VI
GIT & LIVER & NUTRITIONAL DISORDERS MODULE
Paper- I 6
GASTRO INTESTINAL
TRACT AND LIVER-2
Paper- IV-A 3
605
RENAL & EXCRETORY 02 MODULE
CODE: EXC 2
SEMESTER VI
THIRD YEAR M.B; B.S
606
Spiral Sem. Modules

II

4 Week
wks
Second th
Spiral th
Trauma, 6 week
3 week 8 Weeks
/ Burns 2 wk
2 Weeks
th
th
PARALLEL THEMES:
607
MODULE COMMITTEE
SPIRAL 02:
Dr. Qamaruddin Baloch, Professor of Surgery, DMC, DUHS
Dr. Hussain Haroon, Assistant Professor of Medicine, DUHS

Dr. Farooq, Professor of Pharmacology, DUHS
Dr. Kelash Nannkani, Associate Professor of Physiology, DUHS
Dr. Ghulam Murtaza, Associate Professor of Pediatrics, DUHS
Dr. Sadia Akram, Associate Professor of Pathology DUHS
Documented by:
Dr.Tanzeela Khan (Department of Anatomy, Dow Medical College, DUHS &
Principal Office, DMC, DUHS)
Coordinated by:
Dr. Tanzeela khan (Department of Anatomy, Dow Medical College, DUHS &
Principal Office, DMC, DUHS)
Reviewed by:
MODULE COMMITTEE
608
RATIONALE
Renal disorders are commonly encountered in both adult and pediatric clinical practice. Acute
and chronic glomerulonephtritis, nephrotic and nephritic syndromes, acute and cronic renal
failure, urinary tract infections, renal tumours, diseases related to lower urinary tract and
prostate are some of the disorders a doctor will come across in clinical practice.
In this second, clinical spiral module of renal diseases the student shall dwell on the basic
understanding of the anatomy, physiology and biochemical processes attained in the first spiral
and develop the understanding of common renal diseasaes and renal failure and its
management,.
TERMINAL OBJECTIVES
By the end of the renal module, a medical student shall be able to:
Recognize the clinical presentations of common renal diseases in the community.

Diagnose common disorders on the basics of history, examination and clinical
investigations.
Describe the basic principles of management of common disease and make appropriate
referral.
Identify the specific diagnostic tools for renal disease, and their interpretation
Apply preventive measures & prognosis for counseling the patients.
609
BCQS, SEQS EMQS

DIGITAL LIBRARY
SELF STUDY
TUTORIALS
PRACTICAL
LECTURES
SKILL LAB
LIBRARY
VIVA
SBL
OBJECTIVES Assess
ment
ANATOMY EXC 2 Ana 1 1 * *

Anatomy
Development,
histology, Variations,
Revisit structure Gross etc
and function of
renal and excretory PHYSIOLOGY EXC 2 Phy 1 1 * *
Physiology GFR and
system
its regulation
PHYSIOLOGY EXC 2 Phy 2 1 * *

Tubular re-
absorption

Cysts : Congenital
Identify Congenital and acquired cystic
anomalies and
conditions of kidney
cysts of kidneys
SURGERY EXC 2 Sur 1 1 * *
Clinical presentation
of Kidney and Urinary
tract
610
SURGERY EXC 2 Sur 2 1 * *
Elicit relevant MEDICINE EXC 2 Med 1 1 * *

history and Investigation of renal
perform Clinical & urinary diseases
examination of Interpret renal
urinary system, disorders on the
including per-rectal basis of clinical
examination presentations:
EXC 2 Rad 1 1
RADIOLOGY * *
Read and Interpret (IVP/ US/ Renal
lab investigations CT Pyelography,
and imaging Radio nuclear scan
techniques to
/renal arteriography,
reveal the
diagnosis
PRACTICALS PATHOLOGY EXC 2 Pth 2 1.5

* *
Urine analysis ,
protein, urea
PEDIATRICS EXC 2 Ped 1 1.5

* *
Interpret renal
disorders on the
basis of clinical
presentations
SCENARIO EXC 2 Sbl 1 1.5

* *
BASED
LEARNING
Identify the causes, PATHOLOGY EXC 2 Pth 3 * *

underlying patho- Obstructive Uropathy
physiology, 1Urinary out flow
histopathology, Obstruction
clinical (Urolithiasis,
presentation and Hydronephrosis)
management of
611
Urolithiasis and PATHOLOGY EXC 2 Pth 4 * *
obstructive Obstructive Uropathy
uropathies/ Renal 2
colic Urinary out flow
Obstruction
(Prostate)
SURGERY EXC 2 Sur 3 * *

Surgical presentation
and Management of
Urolithiasis
SURGERY EXC 2 Sur 4 * *

Management of
Diseases of Prostate
Identify the causes, PATHOLOGY EXC 2 Pth 5 * *

underlying patho-
physiology, Pathogenesis of
histopathology, Glomerular Disease
clinical
presentation and PATHOLOGY EXC 2 Pth 6
management of * *
Glomerular
Glomerular conditions: nephritic
conditions: Syndrome
nephritic and
nephrotic
PATHOLOGY EXC 2 Pth 7
syndrome
Glomerular
conditions: nephrotic
syndrome
PATHOLOGY EXC 2 Pth 8 * *
Glomerular
conditions associated
with systemic
disorders
MEDICINE EXC 2 Med 2 * *

and management of
Glomerular
conditions: nephritic
and nephrotic
syndrome
612
PEDIATRICS EXC 2 Ped 2 * *
and management of
Glomerular
conditions: nephritic
and nephrotic
syndrome
PATHOLOGY EXC 2 Pth 9 1.5

PRACTICALS Pathology: Urine C/S
SKILL LAB EXC 2 Ugsl 1 1.5

* *
Skill Lab

BASED SBL
LEARNING
PATHOLOGY EXC 2 Pth 10 1 * *
Acute tubular
Describe the necrosis : etiology,
causes, underlying pathogenesis,
patho-physiology, morphology, clinical
histopathology course
and clinical
presentation of PATHOLOGY EXC 2 Pth 11 1
Tubular and * *
Tubulo-interstitial
interstitial nephritis : etiology,
disorders pathogenesis,
morphology, clinical
course
Identify the causes, MEDICINE EXC 2 Med 3 1 * *

underlying patho- Acute Renal failure
physiology,
histopathology,
clinical
presentation and MEDICINE EXC 2 Med 4 1
management of
* *
Chronic Renal failure
acute and chronic Overview renal
renal failure dialysis and renal
transplants
613
Describe the PATHOLOGY EXC 2 Pth 12 1 * *
causes, underlying Pyelonephritis
patho-physiology,
histopathology,
clinical PATHOLOGY EXC 2 Pth 13 1
presentation and
* *
Urinary Tract
management of Infections
Infectious EXC 2 Ped 1
disorders
PEDIATRICS * *
and management of
Infectious disorders
MEDICINE EXC 2 Med 5 1 * *
and management of
Infectious disorders
PHARMACOLO EXC 2 Pha 1 1 * *

GY Diuretics 1
PHARMACOLO EXC 2 Pha 2 1

* *
GY Diuretics 2
PHARMACOLO EXC 2 Pha 3 1.5

* *
PRACTICALS GY Role of Diuretics in
medicine
SKILL LAB EXC 2 Ugsl 2 1.5

* *
Skill Lab

* *
BASED SBL
LEARNING
PATHOLOGY EXC 2 Pth 14 1 * *

Tumors of renal
Identify the causes, system
underlying patho-
physiology,
histopathology, SURGERY 1 * *
clinical EXC 2 Sur 5
presentation and Tumors of renal
management of system
Tumors
614
Revisit fluid, K (Potassium)
electrolyte and Disorders
acid base balance

Na (SODIUM)
Disorders

Management of acid
base balance
disorders
TOPICS OF FORENSIC MEDICINE

Classification of wounds
Blunt and sharp weapons
Laws related to wounds
Irrespirable gases
Asphyxia
TOPICS OF COMMUNITY MEDICINE

Hospital waste management
Hospital Administration
End stage renal disease
615
RENAL AND EXCRETORY 02 MODULE
TIME TABLE
FIRST WEEK
Days 8:30 to 9:30 9:30 to 10:30 10:30 1:30 1:30-3:00
Anatomy Physiology
Functional Anatomy GFR and its
(Development, regulation and its CLINICAL
DAY 5 histology, Variations, applied POSTING
Gross ) physiology
Faculty Name Faculty Name
Venue Venue
Clinical Faculty
Pathology
Surgery
Cysts : Congenital and acquired
Physiology Clinical CLINICAL
Tubular re-absorption presentation of cystic conditions of kidney
DAY 6 POSTING
Faculty Name Kidney and
Venue Faculty Name
Urinary tract Venue
Faculty Name
Venue
616
Days 8:30 to 9:30 9:30 to 10:30 10:30 1:30 1:30-3:00

A- Pathology: Urinary Analysis,
Protein urea, Faculty Name
Venue
Medicine B- FORENSIC Medicine: Faculty
Investigation of renal & Name
urinary diseases Surgery Venue
DAY Interpret renal disorders Congenital CLINICAL C: (C1, C2, C3) Pediatrics :
1 on the basis of clinical anomalies POSTING Interpret renal disorders on the basis
Faculty Name of clinical presentations: Faculty
presentations: Venue Name
Faculty Name Venue
Venue
D SBL: Faculty Name
Venue
E: SELF STUDY
Radiology
Forensic 1. B
(IVP/ US/ Renal Medicine: CLINICAL 2. C
DAY CT Pyelography, Radio Classification of
nuclear scan /renal POSTING 3. D
2 wounds
arteriography, Faculty Name 4. E
Faculty Name Venue LH 5. A
Venue
Pathology
Obstructive Uropathy Community 1. C
1Urinary out flow Medicine CLINICAL 2. D
DAY Obstruction Hospital waste POSTING 3. E
3 (Urolithiasis, management
Hydronephrosis) Faculty Name 4. A
Faculty Name Venue 5. B
Venue
Pathology FORENSIC 1. D
Obstructive Uropathy 2 MEDICINE: CLINICAL 2. E
DAY Urinary out flow Blunt and sharp
POSTING 3. A
4 Obstruction (Prostate) weapons
Faculty Name Faculty Name 4. B
Venue
Venue 5. C
DAY PUBLIC HOLIDAY

5
PATHOLOGY 1. E
Surgery
Pathogenesis of 2. A
DAY Management of Diseases CLINICAL
Glomerular 3. B
6 of Prostate POSTING
Faculty Name
Disease
Faculty Name 4. C
Venue
Venue 5. D
617
Days 8:30 to 9:30 9:30 to 10:30 10:30 1:30 1:30-3:00

Gp A Self Study
Gp B Pathology: Urine C/S
Faculty Name
Pathology Surgery Venue
Glomerular Surgical presentation Gp C Forensic Medicine: War
DAY conditions: and Management of Clinical Gases. Lacrimatous, Phosgene, Di
1 Posting Phosgene Faculty Name
nephritic Syndrome Urolithiasis
Venue
Venue Venue Gp D : Skill Lab (D1)
Faculty Name
Venue
Gp E SBL: Faculty Name
Venue
PATHOLOGY 6. B
Glomerular Community Medicine
Hospital Administration 7. C
DAY conditions: nephrotic Clinical
8. D
2 syndrome Posting
Faculty Name 9. E
Faculty Name Venue
Venue 10. A
Medicine Clinical
Pathology
presentation and 1. C
Glomerular
management of 2. D
DAY conditions associated Clinical
Glomerular conditions: 3. E
with systemic Posting
3 nephritic and nephrotic 4. A
disorders
syndrome 5. B
Faculty Name
Venue Faculty Name
Venue
Pediatrics Clinical faculty: 6. D

Clinical presentation and 7. E
DAY management of Glomerular Medicine Clinical
conditions: nephritic and Acute Renal failure Posting 8. A
4 nephrotic syndrome Faculty Name 9. B
Faculty Name
Venue Venue
10. C
Pathology
Forensic Medicine: Acute tubular necrosis :
DAY Laws related to etiology, pathogenesis,
wounds morphology, clinical Clinical Posting
5
Faculty Name course
Venue Faculty Name
Venue
Clinical faculty: Pathology
Medicine Tubulo-interstitial 6. E
Chronic Renal failure nephritis : etiology, 7. A
DAY Overview renal pathogenesis, Clinical
Posting 8. B
6 dialysis and renal morphology, clinical
transplants course 9. C
Faculty Name Faculty Name 10. D
Venue Venue
618
Days 8:30 to 9:30 9:30 to 10:30 10:30 1:30 1:30-3:00

Gp A Self Study
Gp B : Pharmacology
Tutorial
Role of Diuretics in medicine
Faculty Name
PHARMACOLOGY PATHOLOGY Venue
DAY Diuretics 1 Pyelonephritis Clinical Gp C Forensic Medicine:
1 Faculty Name Faculty Name Posting Practical Faculty Name
Venue Venue
Venue
Gp D : Skill Lab (D2)
Faculty Name
Venue
Gp E SBL: Faculty Name
Venue
COMMUNITY 11. B
PHARMACOLOGY MEDICINE 12. C
DAY Diuretics 2 Hospital Waste Clinical
13. D
2 Faculty Name Management Posting
Venue Faculty Name 14. E
Venue 15. A
FORENSIC 6. C
PATHOLOGY MEDICINE 7. D
DAY Urinary Tract Infections Clinical
Irrespirable gases 8. E
3 Faculty Name
Faculty Name
Posting
Venue 9. A
Venue 10. B
11. D
PATHOLOGY PEDIATRICS 12. E
Tumors of renal Clinical presentation and
DAY management of Clinical 13. A
system Posting
4 Infectious disorders 14. B
Faculty Name
Venue
Faculty Name
Venue 15. C
MEDICINE
BEHAVIORAL
DAY Clinical presentation
SCIENCES Clinical Posting
and management of
5 Infectious disorders
Faculty Name
Venue
Faculty Name
Venue
11. E
MEDICINE 12. A
DAY FORENSIC Clinical
K (Potassium) Disorders
MEDICINE Posting 13. B
6 Faculty Name
Faculty Name Venue 14. C
Venue
15. D
619
Days 8:30 to 9:30 9:30 to 10:30 10:30 1:30 1:30-3:00
COMMUNITY
SURGERY
DAY MEDICINE Clinical
Tumors of renal system
1 Faculty Name
End stage renal disease Posting SELF STUDY
Venue Faculty Name
Venue
MEDICINE MEDICINE
DAY Na (SODIUM) Management of acid base Clinical
2 Disorders balance disorders Posting SELF STUDY
Venue Venue
DAY FORENSIC MEDICINE Clinical

3 Asphyxia Posting SELF STUDY
Faculty Name
Venue
DAY SELF STUDY Clinical

4 Posting SELF STUDY
DAY Clinical
5 SELF STUDY Posting
DAY
6 MODULE EXAM
620
LEARNING OBJECTIVES
ANATOMY
EXC 2 Ana 1 DEVELOPMENT , HISTOLOGY, GROSS, VARIATIONS OF RENAL SYSTEM:
Discuss the components of the urinary system
Discuss the development of kidney
Discuss the gross anatomy of the kidney
Know the histology of the kidney
Discuss the blood supply venous drainage and nerve supply of kidney
PHYSIOLOGY
1) EXC 2 Phy 1 GFR ,FACTORS AFFECTING IT & ITS REGULATION:
Describe glomerular filtration membrane and how it EXCludes blood cells and proteins
from the filtrate
Explain the forces that promote and oppose glomerular filtration
Discuss how will you calculate net filtration pressure if given the magnitude of these
forces
Define glomerular filtration rate (GFR) and discuss Factors affecting GFR
Explain the regulation of GFR (describe how the nervous system, hormones, kidney itself
regulate glomerular filtration).
2) EXC 2 Phy 2 TUBULAR REABSORPTION
Describe the general structure of tubular system
621
Describe the tubular reabsorption at different renal segments
Effect of tubular reabsorption on concentration of urine
Explain the role of ADH and urea
MEDICINE
1. EXC 2 Med 1 INVESTIGATIONS IN RENAL MEDICINE:
Basic and advance renal investigations

When, how, which and what type of investigation to be sent according to renal illness
The basics that how such investigation to be interpret
The significance of test in disease, its prognosis and monitoring
2. EXC 2 Med 2 CLINICAL PRESENTATION AND MANAGEMENT OF GLOMERULAR

CONDITIONS: NEPHRITIC AND NEPHROTIC SYNDROME:
Definition of terms
Basic classification of glomerular diseases
Proteinuria and its types
Difference b/w nephritic and nephrotic syndrome
Approach to a patient with glomerular diseases
Management of nephritic and nephrotic syndrome
EXC 2 Med 3 ACUTE RENAL FAILURE

Describe an overview of anatomy, physiology of urinary system.
Explain the classification of renal failure.
Discuss the clinical picture and presentation of acute renal failure.
EXC 2 Med 4 CHRONIC RENAL FAILURE:

Identify the causes of chronic renal failure
Explain the pathogenesis of renal failure
Describe the signs and symptoms and presentation of chronic renal failure
EXC 2 Med 5 CLINICLE PRESENTATION AND MANAGEMENT OF INFECTIOUS DISORDERS

Identify the causes of chronic renal failure
Explain the pathogenesis of renal failure
Describe the signs and symptoms and presentation of chronic renal failure
622
EXC 2 Med 6 POTASSIUM DISORDERS:
Describe what is the distribution of K in the body .
Enlist the causes of hypokalemia and hyperkalemia.
Discuss the diagnosis and management of these disorders
EXC 2 Med 7 SODIUM DISORDERS:
Describe the distribution of Na in the body .
Enlist the causes of hyponatremia and hypernatremia.
Discuss the diagnosis and management of these disorders.
EXC 2 Med 8 MANAGEMENT OF ACID BASE DISORDERS & ARTERIAL BLOOD GAS
INTERPRETATION:
Describe the distribution of Na in the body .
Enlist the causes of hyponatremia and hypernatremia
Discuss the diagnosis and management of these disorders
PATHOLOGY
EXC 2 Pth 1 CONGENITAL AND ACQUIRED CYSTIC DISEASES OF THE KIDNEY
Classify congenital Anomalies and Cystic Diseases of the Kidney
Briefly discuss each type with reference to clinical features
Enumerate clinical Manifestations of Renal Diseases
EXC 2 Pth 3 OBSTRUCTIVE UROPATHY: URINARY OUTFLOW OBSTRUCTION (UROLITHIASIS)

Enumerate causes of Urinary Tract Obstruction
Define Urolithiasis
Classify renal Calculi and briefly describe silent features of each type
EXC 2 Pth 4 OBSTRUCTIVE UROPATHY 2 (PROSTATE)

Describe the gross anatomy.
Evaluate the causes of Prostitis
Understand the pathogenesis of Prostitis
Explain the management of Prostitis.
Evaluate the clinical course of Prostitis.
623
EXC 2 Pth 5 GLOMERULAR DISEASE
Describe principal systemic manifestations of chronic kidney disease and uremia
Define the glomerular syndromes
Discuss clinical manifestations of glomerular disease
Enumerate immune mechanisms of glomerular injury
EXC 2 Pth 6NEPHRITIC SYNDROME

Describe various glomerular syndromes
Define nephritic syndrome
Pathophysiology and clinical features of nephritic syndrome
Differentiate between nephrotic and nephritic syndrome
EXC 2 Pth 7 NEPHROTIC SYNDROME

Describe various glomerular syndromes
Define nephrotic syndrome
Pathophysiology and clinical features of nephrotic syndrome
Differentiate between nephrotic and nephritic syndrome
EXC 2 Pth 11TUBULO INTERSTITIAL DISEASES:

Define tubulo interstitial injury.
Describe causes & pathogenic mechanisms of tubulo interstitial injury.
Identify predisposing factors of pyelonephritis.
Describe causes, pathogenic mechanisms & morphology of Acute Pyelonephritis.
Describe clinical course of acute pyelonephritis.
identify features of chronic pyelonephritis.
EXC 2 Pth 12CHRONIC PYELONEPHRITIS:

Define chronic pyelonephritis
Enumerate different types of pyelonephritis
Discuss different types of nephropathies.
Define nephrocalcinosis
Explain Multiple Myeloma
EXC 2 Pth 13 URINARY TRACT INFECTIONS:

Identify the causes of UTIs
Classify urinary tract infections according to the degree
Describe the predisposing factors, clinical presentation and methods for treating UTIs
624
EXC 2 Pth 14 TUMORS OF RENAL SYSTEM:
Describe the pathogenesis of renal tumors.
PHARMACOLOGY
EXC 2 Pha 1 DIURETICS 01:

Classify diuretics related to their site of action
Describe the actions of mannitol, frusemide, thiazides, aldosterone antagonists and
carbonic anhydrase inhibitors
Describe the adverse effects of the diuretics
Describe the major applications and toxicities of thiazides, loop diuretics and potassium-
sparing diuretics
EXC 2 Pha 2 DIURETICS 02:

Describe the mechanism of action of alpha blockers for treatinment of BPH including
doxazosin, terazosin, alfuzosin tamsulosin, and silodosin.
Describe the mechanism of action of anti muscarinic
Describe the mechanism of action of 5-reductase inhibitor
Describe common adverse effects of alpha blockers including orthostatic hypotension,
ejaculation changes, nasal congestion, and weakness
SURGERY
EXC 2 Sur 1 INTRODUCTION AND CLINICAL MANIFESTATIONS OF RENAL DISEASES:
Describe basic structure and functions of the kidney
Illustrate main symptoms of renal disease
Assess kidney functions
EXC 2 Sur 2 CONGENITAL UROLOGICAL CONDITIONS:
Renal Aplasia
Solitary kidney
Renal Ectopia
Pelvis kidney
Crossed Dystopia - Unilateral fusion
Horseshoe Kidney
Cystic disease
Solitary Renal Cyst
Polycystic Kidneys
Duplex system
625
Duplex Renal Pelvis
Duplex Ureter
EXC 2 Med 3 SURGICAL PRESENTATION AND MANAGEMENT OF UROLITHIASIS:
Types of stones
Etiology, presentation
Surgical treatment
PAEDIATRICS
EXC 2 Ped 2 CLINICLE PRESENTATION AND MANAGEMENT OF GLOMERULAR CONDITIONS
Definitions and pathophysiology Nephrotic syndrome
Analyze efficacy of different treatment protocols in the treatment of Steroid Sensitive
Nephrotic Syndrome (SSNS)
Come up with an evidence based algorithmic approach to SSNS
CASE BASED LEARNING

EXC 2 SBL 1
Discuss nephritic syndrome.

Recognize patient with proteinuria
Management of proteinuria
Types of proteinuria
EXC 2 Sbl 2
Recognize a patient of chronic renal failure

Investigations of chronic renal failure
Management of chronic renal failure
626
ROUND
WEEKS 1 2 3 TOTAL (TI) T1x100/T2
OFF
ANATOMY 3 7 - 10 17.09 18
BIOCHEMISTRY 4.5 6.5 5.5 16.5 9.65 10
PHYSIOLOGY 5 4 2.5 11.5 19.65 20
PATHOLOGY 1 1 5 7 11.96 12
MICRO - - 1 1 1.70 2
PHARMA - 1 - 1 1.70 2
MEDICINE - 1 4.5 5.5 9.40 10
BEHAVIORAL - 2 - 2 3.41 4
SCIENCES
RADIOLOGY - - 1 1 1.70 2
SKILL LAB 1.5 1.5 3 5.12 6
TOTAL (T2) 13.5 24 19.5 58.5 99.05 100
CBL - 1.5 1.5 3 5.12 5
627
RENAL & EXCRETORY-2 MODULE
(SEMESTER-VI)
THEORY

SEMESTER
ATP 25
EXAM
PAPER-II 80%
One best Questions
20
based on CBL
Total 100
MODULE EXAM
EMQs 10
ATP 20
MODULE PAPER 20%
One best Questions
20
based on CBL
Total 100
STRUCTURED VIVA

SUMMATIVE
ASSESMEN
SEMESTER
EXAM
See Semester
PAPER-IV-B Structured viva
T
Assessment Plan
ASSESSMENT TOOLS
Structured Feedback
Facilitator
NOTE: Paper I & IV-A of Semester-6 Examination are Based on GI & Liver-2 Module.
Paper III & IV-C of Semester-6 Examination are Based on Endocrinology-2 Module.
628
CREDIT HOURS
RENAL & EXCRETORY-2 MODULE

SEMESTER VI
PAPER-II 3
RENAL-2
PAPER-IV B 1.5
629
ENDOCRINOLOGY Module II
Code: END 2
Semester VI
THIRD Year MBBS
630
Spiral Sem. Modules

II

4 Week
wks
Second th
Spiral th
Trauma, 6 week
3 week 8 Weeks
/ Burns 2 wk
2 Weeks
th
th
PARALLEL THEMES:
631
END-2 MODULE COMMITTEE
Dr. Suleman, Asstt. Professor of Pathology, DMC

Dr. Tahseen, Asstt. Professor of Biochemistry, DMC
Dr. Mujtaba, Associate Professor of Anatomy, DMC
Dr. Fuad Shaikh, Senior Lecturer of Pharmacology, DMC
Dr. Kelash, Associate Professor of Physiology, DMC
Dr. Akhtar Baloch, Assistant Professor of Medicine, DMC
Dr. Muzzamil Shabana Ejaz, Assistant Professor of Pediatrics, DMC,CHK
Prepared By:
Coordinated by:
Dr. Fahad Khan
Reviewed by:
Module Committee
632
RATIONALE
The function of the endocrine system is to coordinate and integrate cellular activity within the
whole body by regulating cellular and organ function throughout life and maintaining
homeostasis. Homeostasis, or the maintenance of a constant internal environment, is critical to
ensuring appropriate cellular function.
Common endocrinological disorders like diabetes mellitus, thyrotoxicosis, hypothyroidism,
Cushing syndrome, pituitary disorders, beside the hormonal changes associated with
reproductive organ diseases are necessary to be understood for comprehensive management.
These diseases are commonly encountered in medical practice. In this module with the
integration of the basic knowledge obtained in the first spiral, a sound clinical base is developed.
TERMINAL OBJECTIVE
Medical graduate after completion of 5 years training program should be able to

Describe pathogenesis & clinical presentations of common endocrine & metabolic disorders
Take history, perform physical examinations of endocrine system
And formulate appropriate plan of investigations for attaining differential diagnosis
Practice basic principles of management of endocrine & metabolic disorders.
633
mode of assessment:
Lectures
Demo
Tutorials
Practical
SBL
Self Study
EMQS
One Best,
spotting
Practical /
viva
Skills Lab
Objectives faculty Content / Topic
Modes of information transfer Assesment
REVISIT anatomy,
secretion and Anatomy END2 Ang1 REVISIT anatomy, secretion
regulation, and mechanism of action and function
mechanism of of hormone
action and
function of
hormones of
hypothalamus 1 *
pituitary thyroid
parathyroid,
pancreas and
adrenal gland
Physiology END2 Phy1 Classification and regulation 1 *
of hormones
Identify the END2 Pth1 causes, underlying patho- 1 1.5 * *

causes, underlying Pathology physiology, histopathology, clinical
patho-physiology, presentation of Adenomas of pituitary
histopathology, gland
clinical END2 Pth2 Adenomas of pituitary 1 * *
presentation and gland
outline the
management of Medicine END2 Med1 Diagnosis and outline the 1 * *
hyper and hypo management of Adenomas of pituitary
pituitarism gland
END2 Med2 Diagnosis and outline the 1 *

management of posterior pituitary
gland: Diabetes insipidus
Pharmacology END2 Pha1 Drugs used for replacement 1 * * *

therapy and to inhibit the hyper 1.5
secretion of Adenomas of pituitary
gland
Surgery END2 Sur1 Indication of surgical 1 *

intervention of Adenomas of pituitary
gland
634
Pediatrics END2 Ped1 Outline of Adenomas of 1 *
pituitary gland/ growth hormone
deficiency
SBL END2 Sbl1 ACROMEGALY 1.5

1 1.5 * *
Pathology END2 Pth3 Hypo/ Hyper secretions of
thyroid gland
END2 Pth3 causes, underlying patho- 1 * *
physiology, histopathology and Hypo/
Hyper secretions of thyroid gland
Identify the Medicine END2 Med3 Diagnosis and outline the 1 * *

causes, underlying management of Hypo/ Hyper secretions
patho-physiology, of thyroid gland
histopathology,
clinical Pharmacology END2 Pha2 Drugs used for replacement 1 1.5 *
therapy for hypo secretion and to
presentation and
inhibit Hyper secretions of thyroid
outline the
gland
management of
Hypo/ Hyper Surgery END2 Sur2 Role of surgery in thyroid 1 *
secretions of disorders
thyroid gland
Pediatrics END2 Ped2 Outline the diagnosis and 1 *
management of cretinism and Graves
disease
SBL END2 Sbl2 Graves Disease 1.5
Identify the Pathology END2 Pth4 causes, underlying patho- 1 1.5 * *

causes, underlying physiology, histopathology and Hypo/
patho-physiology, Hyper secretions of parathyroid gland
histopathology,
Medicine END2 Med4 Diagnosis and outline the 1 * *
clinical
management of Hypo/ Hyper secretions
presentation and of parathyroid gland
outline the
management of Pharmacology END2 Pha3 Drugs used for replacement 1 * *
Hypo/ Hyper therapy for hypo secretion of
secretions of parathyroid gland
parathyroid gland
Identify the END2 Pth5 causes, underlying patho- 1 * *

causes, underlying physiology, histopathology and Hypo/
patho-physiology, Pathology Hyper secretions of pancreas
histopathology,
END2 Pth6 Hypo/ Hyper secretions of 1 1. * *
clinical
pancreas 5
presentation and
outline the END2 Pth7 Classification, diagnosis, and 1 * *
management of etiology pathogenesis of diabetes
Hypo/ Hyper mellitus and its complications
secretions of Medicine END2 Med5 Diagnosis and outline the 1 * *
management of Hypo/ Hyper secretions
635
pancreas of pancreas
Management of diabetes mellitus,
acute and chronic complications and
prognosis and counseling
Pharmacology END2 Pha4 Oral hypo glycemic drugs / 1 * *
Anti Diabetic Drugs and insulin therapy
Surgery END2 Sur3 Indications of surgical 1 * *
intervention of Hyper secretions of
pancreas
Pediatrics END2 Ped 3 Outline the diagnosis and 1 * *
management of juvenile diabetes
mellitus acute and chronic
complications, prognosis and
counseling
SBL END2 Sbl 3 Diabetes 1.
5
Identify the END2 Pth8 causes, underlying patho- 1 1. * *
causes, underlying physiology, histopathology and Hypo/ 5
patho-physiology, Pathology Hyper secretions of adrenal gland
histopathology,
END2 Pth8 Clinical features and 1 * *
clinical
diagnosis of Hypo/ Hyper secretions of
presentation and adrenal gland
outline the END2 Med6 Diagnosis, acute 1 *
management of emergencies and outline the
hypo and hyper Medicine management of Hypo/ Hyper secretions
secretion of of adrenal gland
adrenal gland END2 Med6 Addison disease, Cushing 1 *
syndrome, Pheochromocytomas,
Conns syndrome
Pharmacology END2 Pha5 Drugs used for replacement 1 1. * *
therapy for hypo secretion and to 5
inhibit Hyper secretions of adrenal
gland
Surgery END2 Sur4 Indications of surgical *
intervention of Hypo/ Hyper
secretions of adrenal gland
Community Community END2 Com1 School Health services 1 *
Medicine Medicine
Behavioral Behavioral END2 Beh1 Breaking Bad News 1 *

Sciences Sciences
END2 Beh2 Professionalism in health 1 *
care
Forensic medicine Forensic END2 Fmm1 Custodial death 1 * *
medicine
Forensic END2 Fmm2 torture 1 * *
medicine
Forensic END2 Fmm3 Animal Poison: Snake 1.5 * *
medicine Poison
Forensic END2 Fmm4 Insecticide poison 1.5 * *
medicine
636
ENDOCRINOLOGY 02 MODULE
TIME TABLE
FIRST WEEK
Days 8:30 to 9:30 9:30 to 10:30 10:30 1:30 1:30-3:00
Gp A Self Study
Gp B : (Pharma tutorial)
Growth Hormone and
Functional anatomy pharmacological applications
REVISIT anatomy,
Pathology Gp C Forensic Medicine
secretion and
Overview of pituitary tutorial (Poisonous Plants:-
mechanism of action
pathologies Castor, Croton Abrus,
1 and function of Clinical Posting
hormones Semicarpus )
Name of faculty
Venue
Name of faculty Gp D: Self Study
Venue
Gp E: (Pathology
tutorial)pituitary function
tests Name of faculty
Venue
Anatomy Physiology 16. B
Pituitary anatomy and Classification and 17. C
2 functions regulation of hormones Clinical Posting 18. D
Name of faculty 19. E
Name of faculty
Venue 20. A
Venue
16. C
MEDICINE
Overview of pituitary PHARMACOLOGY 17. D
syndromes Pituitary hormone in 18. E
3 Clinical Posting
clinical practice 19. A
Name of faculty Name of faculty
20. B
Venue Venue
Medicine
FORENSIC MEDICINE clinical presentation of
INSECTICIDE POISONING pituitary tumors and
4 Clinical Posting
Name of faculty diagnosis
Venue
NEUROSURGERY
BEHAVIORAL SCIENCES Clinical presentation of
16. D
Pituitary tumors,
Professionalism 17. E
diagnosis &
5 In health care Clinical Posting 18. A
management
19. B
Name of faculty
Name of faculty 20. C
Venue
Venue
637
Endocrinology MODULE 2
10:30
Days 8:30 to 9:30 9:30 to 10:30 1:30-3:00
1:30
1.E
PEDIATRICS 2.A
Clinical presentation, 3.B
diagnosis & management of Clinical 4.C
1
Hypo-pituitary (Short Self Study Posting 5.D
stature)
1.Gp A Self Study
2.Gp B : (Pharmacology Tutorial) Antithyroid

drugs and its pharmacological applications
PATHOLOGY Name of faculty Venue
Hypo/ Hyper secretions of
thyroid gland
FORENSIC MEDICINE
Name of faculty Venue 3.Gp C :Pathology practical(Histo pathology
Animal Poison: Snake
2 Clinical Posting of thyroid gland)
Poison
4.Gp D1 : Skill Lab (IV cannulation and
venipuncture)
Gp D2: self study

5.Gp E : Forensic Medicine artificial
insemination and its medico legal aspects
PHARMACOLOGY
PATHOLOGY Drugs used for 1.B
Hypo/ Hyperthyroidism replacement therapy for 2.C
3 secretions Causes, Clinical hypo secretion and to Clinical Posting 3.D
features inhibit Hyper secretions of 4.E
Name of faculty Venue thyroid gland 5.A
MEDICINE 1.C
PATHOLOGY 2.D
Clinical feature, Diagnosis
Tumors of thyroid tumors; 3.E
4 and Management of Clinical Posting
Primary , secondary 4.A
Hypo-thyroidism
Name of faculty Venue 5.B
SURGERY MEDICINE
Approach to a patient with Clinical feature, Diagnosis
10:30-12:00
5 thyroid nodule & Role of & Management of Hyper-
Clinical Posting
surgery in thyroid disorders thyroidism
PEDIATRICS 1.D
Clinical feature, Diagnosis, COMMUNITY MEDICINE
2.E
school health services
6 Management of congenital Clinical Posting 3.A
Name of faculty
& acquired hypothyroidism 4.B
Venue 5.C
638
Days 8:30 to 9:30 9:30 to 10:30 10:30 1:30 1:30-3:00
PATHOLOGY 1.E
causes, underlying patho- ANTI THYROID
2.A
physiology, histopathology MEDICATIONS
1 Clinical Posting 3.B
and Hypo/ Hyper secretions Name of faculty
of parathyroid gland Venue 4.C
Name of faculty Venue 5.D
1.Gp A Self Study

2.Gp B : Pharmacology Tutorial (
pharmacology of steroids) Name of
PATHOLOGY
faculty Venue
causes, underlying patho-
3.Gp C pathology practical Lab
physiology, histopathology
2 Self study Clinical Posting Evaluation of Endocrine Diseases
and Hypo/ Hyper secretions
of Adrenal gland
4.Gp D2 : Skill Lab(IV cannulation and
Name of faculty Venue venepuncture)
Gp D1 : self study
Gp E SBL:
SURGERY
MEDICINE
Indications of surgical 11. B
Clinical feature, Diagnosis
intervention of Hyper 12. C
and
3 secretions of Clinical Posting 13. D
Management of hypo &
parathyroid gland 14. E
hyper parathyroid gland
Name of faculty 15. A
Venue
MEDICINE 21. C
Causes, Clinical features, 22. D
COMMUNITY MEDICINE
4 diagnosis & management of Clinical Posting 23. E
Addisons Disease medical bioethics
24. A
25. B
MEDICINE
Causes, Clinical features,
PHARMACOLOGY diagnosis &
5 Glucocorticoids management of Cushing Clinical Posting
Name of faculty Venue Syndrome
Name of faculty
Venue
21. D
22. E
BEHAVIORAL SCIENCES
6 SELF STUDY Clinical Posting 23. A
Breaking bad news
24. B
25. C
639
Days 8:30 to 9:30 9:30 to 10:30 10:30 1:30 1:30-3:00
PATHOLOGY Clinical Posting 1. E
Pathogenesis of type 1 & II PHARMACOLOGY 2. A
diabetes mellitus Oral hypoglycemic 3.B
1 4.C
5.D
Venue
PEDIATRICS PATHOLOGY Clinical Posting 1.Gp A and Gp B: Pharmacology

Clinical Features, Diagnosis and Pathogenesis of Tutorial(pharmacology of oral
Management of Diabetes complications of hypoglycemics and insulin) Name of
Mellitus & DKA diabetes mellitus faculty Venue
2 Name of faculty Venue Name of faculty 2.Gp C pathology tutorial (Diabetic
Venue ketoacidosis; pathogenesis and clinical
pathology Name of faculty Venue
3.Gp D and Gp E SBL:
PATHOLOGY MEDICINE Clinical Posting 1. C

Hypo/ Hyper secretion of Management of patient 2. D and E
pancreas: causes, Clinical with Diabetes Mellitus 3. A and B
3 features, tumors; Primary , (Type I & II)
secondary, Insulinoma,
glucogonama, Name of faculty
PHARMACOLOGY Clinical Posting 1. D and E
Insulin Therapy
2. A and B
Name of faculty Venue Self study
4 3. C
5 STUDY LEAVE
MODULE TEST
6
640
LEARNING OBJECTIVES
objectives:
ANATOMY
END2 Ang1 Anatomical Features of the Endocrine Glands

Recall the anatomy of the endocrine glands.
Define the relations of these endocrine glands.
Describe Blood vessels supplying these endocrine glands.
Describe Nerve supply of these endocrine glands.
PHYSIOLOGY
END2 Phy1 Classification and Regulation of Hormones

Enlist classification of hormones
Describe mechanism of regulation of hormones.
PATHOLOGY
END2Pth1 Adenomas of Pituitary Gland-1
Identify the causes

Explain underlying patho-physiology, histopathology,
describe clinical presentation and management of hyper and hypo pituitarism
END2Pth2 Adenomas of pituitary gland-2
Discuss types and clinical features of Pituitary Adenoma

Describe the management of adenomas of pituitary glands
END2Pth3 Causes, underlying patho-physiology, histopathology and Hypo/ Hyper secretions
of thyroid gland
Discuss different causes of hypo and hyper secretion of thyroid gland.

Identify characteristic histo-pathological features of thyroid gland
641
of parathyroid gland
Discuss different causes of hypo and hyper secretion of parathyroid gland.

Identify characteristic histo-pathological features of parathyroid gland

of Adrenal Gland
Discuss different causes of hypo and hyper secretion of Adrenal gland.

Identify characteristic histo pathological features of Adrenal gland
END2Pth6 causes, underlying patho-physiology, histopathology and Hypo/ Hyper secretions

of Pancreas
Discuss different causes of hypo and hyper secretion of Pancreas.

Identify characteristic histo pathological features of Diabetes
Discuss complications of Diabetes Mellitus
MEDICINE
END2Med1 Diagnosis and outline the management of Adenomas of pituitary gland
Identify the causes of pituitary gland adenomas

Describe underlying patho-physiology and clinical presentation
Describe management of hyper and hypo pituitarism
END2Med2 Diagnosis and outline the management of posterior pituitary gland: Diabetes
insipidus
Identify the causes, underlying patho-physiology of diabetes insipidus

Describe clinical presentation and outline the management of Diabetes Insipidus
642
END2Med3 Diagnosis and outline the management of Hypo/ Hyper secretions of thyroid
gland
Identify the causes, underlying patho-physiology of hypothyroidism

Identify the causes, underlying patho-physiology of hyperthyroidism
Describe clinical presentation and outline the management of hypothyroidism
Describe clinical presentation and outline the management of hyperthyroidism
END2Med4 Diagnosis and outline the management of Hypo/ Hyper secretions of adrenal
gland
Identify the causes, underlying patho-physiology of adrenal gland hypo & hyper
secretions
Describe clinical presentation and outline the management of adrenal gland hypo &
hyper secretions
END2Med5 Diagnosis and outline the management of Diabetes Mellitus and its
complications:
Identify the causes, underlying patho-physiology of diabetes mellitus

Describe clinical presentation and outline the management Diabetes Mellitus
Describe the complications of untreated diabetes mellitus
SURGERY
END2Sur1 Indication of surgical intervention of Adenomas of pituitary gland
Identify the causes, underlying patho-physiology, clinical presentation of pitutitary gland

adenomas
Describe the surgical management of Adenoma of pituitary gland
END2Sur2 Role of surgery in thyroid disorders

Identify the causes, underlying patho-physiology, clinical presentation of thyroid
disorders
Describe the surgical management of thyroid disorders.
END2Sur3 Indications of surgical intervention of hyper secretions of pancreas
Identify the causes, underlying patho-physiology, clinical presentation of tumors of

pancreas.
Give indication for surgical management of pancreatic disorders
Outline the surgical management of tumors of pancreas.
643
END2Sur4 Indications of surgical intervention of Hypo/ Hyper secretions of adrenal gland
Identify the causes, underlying patho-physiology of adrenal gland secretion disorders

Describe clinical presentation of adrenal gland disorders
Outline the surgical management of tumors of adrenal gland.
PHARMACOLOGY
END2Pha1 Drugs used for replacement therapy and to inhibit the hyper secretion of
Adenomas of pituitary gland
Enlist the drugs used in management of pituitary disorders

Describe the mechanism of action, adverse effects & contraindications of drugs used in
pituitary gland adenomas
END2Pha2 Drugs used for replacement therapy for hypo secretion and to inhibit Hyper
secretions of thyroid gland
Enlist and discuss drugs used in management of thyroid disorders.

hypothyroidism
hyperthyroidism
END2Pha3 Drugs used for replacement therapy for hypo secretion and to inhibit Hyper
secretions of adrenal gland
Classify and discuss drugs used in management of adrenal disorders

hypo secretion of adrenal glands
hyper secretion of adrenal glands
END2Pha4 Drugs used for the management of diabetes mellitus
Classify and discuss mechanism of action of oral hypoglycemic drugs

Classify & discuss mechanism of action, indications of insulin use in management of
diabetes mellitus
644
PEDIATRICS
END2Ped1 Outline of Adenomas of pituitary gland/ growth hormone deficiency
Identify the causes, underlying patho-physiology of adenomas of pituitary gland

Describe clinical presentation and outline the management of pituitary gland /growth
hormone deficiency in children.
END2Ped2 Outline the diagnosis and management of cretinism and Graves disease
Identify the causes, underlying patho-physiology of hyper secretion of thyroid hormones

Describe clinical presentation and outline the management of cretinism and Graves
disease.
END2Ped3 Outline the diagnosis and management of juvenile Diabetes Mellitus
Identify the causes, underlying patho-physiology of diabetes mellitus in paediatric

patients
Describe clinical presentation and outline the management of juvenile diabetes mellitus.
FORENSIC MEDICINE
END2Fmm1 Torture
Define torture
Discuss various techniques of torture
Describe sequel of torture
Describe the duties of medical doctor for managing patient of torture
Discuss ethical issues in relation to various types of torture
END2Fmm2 Custodial Death

Define Custodial Deaths
Discuss Medico legal Importance Of Custodial Deaths
Enumerate Causes Of Custodial Deaths
Discuss Autopsy Procedure In Cases Of Custodial Deaths
645
END2Fmm3 Snake Poison
Discuss types of snakes

Describe stages of intoxications and antidotes
Define and describe various fatal dose of snake poison
Describe clinical symptoms of snake bite according to various common snakes
discuss postmortem findings
discuss medico legal importance of snake bite and poisoning
END2Fmm4 Insecticides
Discuss Stages of intoxications and antidotes

Define and discuss Fatal Dose of various insecticides
Discuss Clinical Symptoms of insecticide poisoning
Describe Postmortem Findings of insecticide poisoning
Discuss Medico Legal Importance
COMMUNITY MEDICINE
END2Com1 School Health Services

Discuss goal and objectives of school health services
Identify the importance and current practice of school health services in local scenario
BEHAVIORAL SCIENCES
END2Beh1 Breaking Bad News

Discuss techniques of how to break bad news in clinical scenario
END2Beh2 Professionalism in health care
Discuss objectives and goals of professionalism in health care.
646
Endocrinology Module:
I. Arterial Puncture
INTRODUCTION (RATIONALE)
Since an arterial blood sample is necessary for the blood gas analysis, the procedure of arterial
puncture is one of the most important skills that health professionals should possess.
LEARNING OBJECTIVES
After the sessions the students should be able to:
Demonstrate the technique for performing an arterial puncture on a manikin.

EQUIPMENTS
1. Syringe
2. Sharp Container
3. Spirit Swab
4. Disposable Gloves
5. Adhesive Tapes
6. Ice for transport
647
SCANERIO BASED LEARNING
END2 Sbl1
Identify the anatomical structures involved in these physical findings.

Describe the physiology of Growth Hormone secretion and regulation.
Correlate the physical findings of underlying hormonal disorder with normal functions.
Interpret the investigations of relevant gland.
To prescribed the treatment and monitor the response of treatment.
END2 Sbl2
Describe the secretion and regulation of insulin

Describe the pathogenesis Diabetes Mellitus
Identify the anatomical structure involved.
Diagnose the type of Diabetes mellitus
How to manage the Diabetic patients
Identify and manage the diabetic complications
Identify metabolic syndrome and its management.
END2 Sbl3
Understanding pathophysiology of Addisons disease.

Able to diagnose hormonal problems on basis of clinical features.
Able to identify anatomical structures involved.
Able to diagnose Addisons disease on basis of investigations and to correlate with
clinical features.
END2 Sbl4
Discuss the structure and functions of thyroid gland

Recognize the mechanism of action of thyroid Hormones and regulation
Relate the clinical picture with the presentation of such clinical condition.
dentify the anatomical structures of the endocrine gland in front of the neck
Discuss the synthesis of T3 T4
Interpret thyroid function tests.
648
WEEKS/HOURS 1st 2nd 3rd 4th TOTAL *** ROUND OFF
PATHOLOGY 2.5 4.5 3.5 4.5 15 27.27 27
ANATOMY 2 - - - 2 3.63 4
PHYSIOLOGY - - - 1 1.8 2
1
MEDICINE 2 2 3 1 8 14.5 15
PAEDS - 2 - 1 3 5.25 5
PHARMACOLOGY 2.5 2.5 3.5 2.5 11 20 20
COMMUNITY - 1 1 - 2 3.63 4
MEDICINE
FORENSIC
2.5 2.5 - - 5 9.09 9
MEDICINE
SURGERY 1 1 1 - 3 5.25 5
BEHAVIORAL 1 - 1 - 2 3.63 4
SCIENCES
Total 2 SBL - - 1.5 1.5 3 5.25 10
TOTAL T1 12 15.5 14.5 10.4 55 100 100
649
(SEMESTER-VI)
THEORY

SEMESTER EXAM
ATP 25 80%
PAPER-III
One best Questions
20
based on CBL
Total 100
MODULE EXAM
EMQs 10
ATP 20
MODULE PAPER 20%
One best Questions
20
based on CBL
Total 100
STRUCTURED VIVA

SUMMATI
ER EXAM
ASSESM
SEMEST
See Semester
ENT
VE
PAPER-IV-C Structured viva

Assessment Plan
ASSESSMENT TOOLS
Structured Feedback
Facilitator
NOTE:
Paper I & IV-A of Semester-6 Examination are Based on GIT &Liver-02 Module.
Paper II & IV-B of Semester-6 Examination are Based on Renal & Excretory Sys -02 Module.
650
CREDIT HOURS
SEMESTER-VI
PAPER-III 3
END-2
PAPER- IV-C 1.5
651
CREDIT
HOURS

80 Marks
I GIT & Liver-2 Module
Marks 6
20 Marks
(Module Exam)
Renal & EXC Sys-2

Module 40 Marks
II Renal & EXC Sys-2 Marks 3
Module 10 Marks
(Module Exam)
Endocrinology-2 Module
40 Marks
III Endocrinology-2 Module
10 Marks
Marks 3
(Module Exam)

a
(Viva)
50 Marks 3
100
IV b
Renal & EXC Sys-2 Module
(Viva)
25 Marks Marks 1.5
Endocrinology-2 Module
C
(Viva)
25 Marks 1.5
652
653
SEMESTER -7
ENT-II Module 3 Weeks 4.5 Credit Hours
Orthopedic-II Module 6 Weeks 6 Credit Hours
Reeproduction-II Module 8 Weeks 7.5 Credit Hours
654
Ear, Nose & Throat (ENT) MODULE
Code: (ENT 02)
Semester:VII/VIII
Fourth Year MBBS
655
Spiral Sem. Modules

II

4 Week
wks
Second th
Spiral th
Trauma, 6 week
3 week 8 Weeks
/ Burns 2 wk
2 Weeks
th
th
PARALLEL THEMES:
656
MODULE COMMITTEE
Prof. Dr Salahuddin Afsar, Professor of Medicine, DUHS

Prof Dr. Salman Matiullah ,Chairperson ENT. DUHS
Prof Dr. Umar Farooq, Professor ENT Unit-II ,DUHS
Prof Dr. Saleem Marfani , Professor ENT Unit-I ,DUHS
Dr. Atif Hafeez , Assistant Professor ENT Unit-I ,DUHS
Dr. Iqbal Kayani, Assistant Professor ENT Unit-II ,DUHS
Dr. Murtaza Ehsan, Assistant Professor ENT Unit-II ,DUHS
Dr. Rukhsana Rubeen, Associate Professor of Biochemistry , DUHS
MODULE IMPLEMENTATION BY:
Module Chief Coordinator: Dr Naheed Khan
MODULE COORDINATOR:
DR. SAIMA RASHID
Documented by:
DR SAIMA RASHID
Reviewed by:
Modular committee
657
RATIONALE:
Some of the commonest diseases encountered by a general practitioner belong to the ear, nose,
throat and head and neck region. A medical graduate should have sound knowledge of
symptomatology of ENT diseases, their diagnosis and principles of management. They should
be able to order and interpret pertinent investigations and treat some of the common problems
along with adequate referral where appropriate.
In the Head and Neck mmodule in the basic sciences spiral has prepared the student with the
background of anatomy , physiology and basic pathology of this region. Based on this
foundation the student shall acquire the clinical knowledge required for diagnosis and
management of diseases related to ear, nose and throat.
TERMINAL OBJECTIVE:
At the end of this module students should be able to:
Review the anatomy of ear, nose and throat

Recall the physiology of hearing and olfaction
Discuss the pathophysiology, diagnosis, clinical features and management of diseases
of external, middle and inner ear
Review the pathology of oral cavity and salivary, oropharynx and hypopharynx
Evaluate of the complications trauma to nose
Recognize the neoplastic conditions of oral cavity, larynx and esophagus and discuss
the management.
Analyse the complications caused by foreign bodies in inner ear and nose and discuss
their management.
Illustrate the indication for tracheostomy and explain its procedure
658
Lectures
Demo:
Tutorials
Practical
CBL
Self Study
spottin
Digital library
BCQs, EMQs
ATP
Viva
Skills Lab
Objectives
Teaching
Content / Topic
Faculty
ENT 2 Ang 1 Review the *

Anatomy of Ear 1 *
ENT 2 Ang 2 Review of

Anatomy of Nose
* *
Describe the Anatomy

Applied Anatomy ENT 2 Ang 3 Review of
and Physiology of Anatomy of Oral Cavity
ENT (Review of Tongue,
* *
Pharynx, Palate,
Salivary Glands)
ENT 2 Phy 1 Review

of the Physiology of
Physiology 1 * *
Hearing
Recognize the ENT ENT 2 Ent 1 Diseases

Clinical Of External Ear 1 *
*
Manifestations,
Symptoms And ENT 2 Ent 2 Hearing
Signs Of ENT 1 * *
Impairment
Diseases, form a
Differential ENT 2 Ent 3 Diseases Of
Diagnosis and
Middle Ear 1 * *
Interpret Various
Pertinent AOM / ASOM
Investigations,
along with an ENT 2 Ent 4 Diseases
understanding of Of Middle Ear - CSOM
1 * *
Principles Of and Choleastatoma
Management Of
659
Common ENT- ENT 2 Ent 5 Diseases Of
Head & Neck Inner Ear 1 * *
Diseases
Enlist the etiology * *

And Pathology Of Pathology
ENT 2 Pth 1 Review of
Common ENT Pathology of the Ear
Problems 1
Nose and Throat
ENT 2 Pth 2 Review of

Pathology of the Oral
Cavity and Salivary
Glands
* *
ENT 2 Ent 6
Allergic, Inflammatory,
Neoplastic Diseases Of 1 * *
The Nose And PNS-1
ENT 2 Ent 7 Trauma

of the Nose, DNS,
1 * *
Rhinolith / foreign
body, CSF rhinorrhea
ENT 2 Ent 8
Epistaxis and
Malignancies of Nose 1 * *
and PNS
ENT 2 Ent 9
`1 * *
Nasopharynx
ENT 2 Pha 1 Review Of

Drugs Used In ENT 1 * *
ENT 2 Ent 10 1 *
*
Nasal bone fracture
Discuss the Ent 2 Ent 11 Oral
Indication, Dosage Cavity 1 * *
& Side Effects Of
Common Drugs ENT 2 Ent12 Neoplastic
Used In ENT conditions of oral
1 * *
cavity
ENT 2 Ent 13 Disorders

of the Salivary Glands 1 * *
ENT 2 Ent 14
Oropharynx 1 * *
660
ENT 2 Ent 15
Hypopharynx 1 * *
ENT 2 Ent 16 Diseases

of the Larynx 1 * *
ENT 2 Ent 17
Laryngeal Paralysis and 1 * *
Carcinoma of Larynx
ENT 2 Ent18 Stridor,
Foreign bodies in 1 * *
Airway, Tracheostomy
ENT 2 Ent 19
1 * *
Oesophageal Disorders
ENT 2 Ent 20 Head and 1
Neck * *
Describe the
Pharmacol
Indication, Dosage ENT 2 Pha 2 Use of
& Side Effects Of ogy
antiallergies 1 * *
Common Drugs
Used In ENT
SKILL LAB Ent 2 Skl 1

1.5 * *
Otoscopy
SBL
* *
3
PRACTICAL ENT 2 Ent 21

1.5 * *
examination
Describe
bioethics,medical ENT 2 Eth 1 Types of
1 * *
ethics,practical Ethics
ethics.
Describe types of ETHICS ENT 2 Eth 2 Informed

1 * *
informed consent Consent .
Describe some
principles of
ENT 2 Ethics3 1 * *
Research Ethics
RESEARCH ETHICS
661
Describe respect
for
autonomy,Privacy
ENT 2 Eth 4 PRIVACY 1 * *
,and its types
define
Confidentiality
Describe Human
rights ,the rights
of the patient , its
ENT 2 Eth 5
importance and 1 * *
THE RIGHTS OF PATIENT
describe the
duties of
physicians
662
ENT-2 MODULE
TIME TABLE
FIRST WEEK
Days 08:30 to 09:30 09:30 to 10:30 10:30 to 12:30 1:30 to 03:00

1. GP=A1, SBL-1 (Ward
ENT-I) NAME OF
FACULTY UNIT-I
2.GP= A2, SBL-2 NAME
ANATOMY OF FACULTY NEW PDC
ENT
1 Review of Anatomy of the BLOCK, DMC, HALL 104
Diseases of External Ear CLINICAL
Ear 3.GP=A3, Skill Lab
NAME OF FACULTY POSTING
NAME OF FACULTY Otoscopy
VENUE
VENUE
4.GP=A4, History &
Examination of Ear
(Ward ENT I )
5.GP=A5, SELF STUDY
2 PUBLIC HOLIDAY
PHYSIOLOGY 1. A2
Physiology Of Hearing ENT 2. B1
3 Hearing Impairment CLINICAL 3. B2
(Revisit)
NAME OF FACULTY POSTING 4. C1
NAME OF FACULTY VENUE 5. A1
VENUE
ENT ENT
Diseases of Middle Ear- 1. B1
Diseases of Middle Ear- CSOM CLINICAL 2. B2
4 ASOM NAME OF FACULTY POSTING 3. C1
4. A1
NAME OF FACULTY
VENUE 5. A2
VENUE
ENT
1. B2 Diseases of Middle Ear-
2. C1 CSOM CLINICAL
5 3. A1 NAME OF FACULTY POSTING
4. A2
5. B1 VENUE
ENT
ENT NOSE- Allergic, 1. C1
Inflammatory, Neoplastic 2. A1
6 Diseases of Inner Ear CLINICAL
Diseases Of The Nose And 3. A2
PNS-I 4. B1
VENUE 5. B2
NAME OF FACULTY
VENUE
663
SEMESTER VII
ENT MODULE
Time Table Week-2
10:30 to 1:30 to 03:00
Days 08:30 to 09:30 09:30 to 10:30
1:00
GP=A1=SBL-3 VENUE NAME OF
PATHOLOGY FACULTY
ENT
Review Of Pathology Of NOSE- Allergic, Inflammatory, GP=A2, SBL-4 VENUE NAME OF
1 The ENT Neoplastic Diseases Of The CLINICAL FACULTY
Nose And PNS-II POSTING GP= A3 VENUE Otoscopy
NAME OF FACULTY NAME OF FACULTY GP=A4, History & Examination of
VENUE Oral ,Nasal Cavity VENUE
VENUE GP=A5, SELF STUDY
ENT ENT 1. A2
NOSE
2 NOSE CLINICAL 2. A3
(Epistaxis and Malignancies of
(Trauma, DNS) the Nose and PNS)
3. A4
POSTING
NAME OF FACULTY NAME OF FACULTY 4. A5
VENUE VENUE 5. A1
PHARMACOLOGY 1. A3
ENT Review of Drugs used in ENT
CLINICAL 2. A4
3 Nasopharynx NAME OF FACULTY
POSTING 3. A5
NAME OF FACULTY
VENUE
4. A1
VENUE
5. A2
PATHOLOGY
ENT 1. A4
Review of Pathology of the
Oral Cavity CLINICAL 2. A5
Oral Cavity and Salivary
4 NAME OF FACULTY POSTING 3. A1
Glands
VENUE 5. A3
ENT
Neoplastic Conditions Of 9:30 12:00
5 Oral Cavity CLINICAL POSTING
NAME OF FACULTY
VENUE
ENT ENT 1. A5
Oropharynx SALIVARY GLANDS 2. A1
CLINICAL
6 NAME OF FACULTY NAME OF FACULTY 3. A2
POSTING
VENUE VENUE 4. A3
5. A4
664
SEMESTER VII
ENT MODULE
Time Table Week-3
Days 08:30 to 09:30 09:30 to 10:30 10:30 to 1:00 1:30 to 03:00

ENT
ENT Diseases of the Larynx ETHICS

CLINICAL
1 NAME OF FACULTY
Diseases of the Larynx POSTING
VENUE
ENT
Carcinoma Larynx and
ENT
Laryngeal Paralysis Hypopharynx CLINICAL ETHICS
2
NAME OF FACULTY NAME OF FACULTY POSTING NAME OF FACULTY
VENUE VENUE
VENUE
ENT ENT
Oesophageal Disorders CLINICAL
Stridor, Foreign Bodies, ETHICS
3 Tracheostomy NAME OF FACULTY POSTING
NAME OF FACULTY
VENUE
VENUE
ENT
ENT Pharmacology CLINICAL ETHICS
4 Head And Neck Use Of Anti Allergies
POSTING NAME OF FACULTY
VENUE VENUE
VENUE
ETHICS 9:30 12:00

5 NAME OF FACULTY CLINICAL POSTING
VENUE
6 SELF-STUDY
665
LEARNING OBJECTIVES
ANATOMY
1. Ent 2 Ang 1 REVISIT : ANATOMY OF EAR
Discuss the division of ear in parts.

Identify the parts of external ear.
Identify the parts of middle ear.
Identify the parts of internal ear
2. Ent 2 Ang 2 REVISIT : ANATOMY OF NOSE
Discuss the division of nose in parts.

Identify the parts of nose.
3. Ent 2 Ang 3 REVISIT : ANATOMY OF ORAL CAVITY
Identify the parts of tongue.

Identify the parts of pharynx.
Identify the parts of salivary glands.
PHYSIOLOGY
1. Ent 2 Phy 1 SENSE OF HEARING, ITS MECHANISM AND AUDITORY

PATHWAY.
Describe the components and functions of the external, middle, and inner ear.
Identify the sound stimulus.
Enlist the parts of the inner ear and their roles in equilibrium and hearing.
Discuss the Auditory Physiology.
Explain the pathways for the sensations of hearing.
Diagnose the Auditory Pathology.
666
PATHOLOGY
1. Ent 2 Pth 1 REVIEW OF EAR, NOSE AND THROAT :
Explain Otitis Externa and Otitis media .

Describe the etiology and pathogenesis of each of the following curious
conditions:
Cauliflower ear,cholesteatoma, otosclerosis.
Describe the pathogenesis of mnire's disease rhinitis, nasal polyp & tumors of
nose, sinuses & nasopharynx
Differentiate the laryngeal inflammation, polyps, papillomas, & laryngeal
carcinoma
Brief about the congenital lesions of neck & paraganglioma
2. Ent 2 Pth 2 PATHOLOGY OF ORAL CAVITY
Discuss caries, gingivitis, reactive nodules of oral cavity

Describe the pathogenesis of Infections of oral cavity
Classify & characterise of oral cavity tumors
Classify of odontogenic cysts & tumors
Desribe common salivary gland lesions including retention cysts, sialadenitis &
tumors
PHARMACOLOGY
1. Ent 2 Pha 1 REVIEW OF DRUGS USED IN ENT
Explain about oral amoxicillin, trimethoprim-sulfamethoxazole, or doxycycline,

given for 3 to 10 days, are the recommended first-line antibiotics for the
treatment of moderate to severe acute sinusitis.
Interpret the incidence of penicillin-resistant S. pneumoniae andbeta-lactamase

producing organisms causing acute sinusitis has been steadily increasing in the
community.
Enlist different alternative agents including Cefpodoxime, Cefuroxime, Cefdinir.
667
2. Ent 2 Pha 2 SIDE EFFECTS OF ENT DRUGS
Review the drugs and antibiotics used in ENT uses and side effects .
Discuss the significance of steroids , anti allergies, nasal decongestants and
topical sprays.
Discuss the toxicity of local and topical anesthetics used in ENT
(XYLOCAINE )
Explain drug interactions with systemic disease.
ENT
1. Ent 2 Ent 1 DISEASES OF EXTERNAL EAR
Diagnose the clinical manifestation of diseases of external ear and their basic
management.
Discuss of methods of removal of wax ,fungus and foreign body from Ear.
Identify when to refer the patient to the concerned speciality.
2. Ent 2 Ent 2 HEARING IMPAIRMENT
Diagnose the clinical manifestation and to be able to request appropriate

investigations
Interpret lab investigations for basic management.
Realise when torefer the patient to the relevant specialty
Describe the rehabilitation of deaf patient.
3. Ent 2 Ent 3 DISEASES OF MIDDLE EAR (ASOM)
Diagnose the clinical manifestations of diseases of middle ear and their basic
management.
Recognize when to refer the patient to the concerned speciality.
Follow guidelines for treatment of discharging ear.
Describe the management of OTITIS MEDIA (ASOM).
Recognize the need of surgery and when to refer patient to the relevant specialty.
4. Ent 2 Ent 4 DISEASES OF MIDDLE EAR (CSOM)
Diagnose the clinical manifestations of diseases of middle ear(CSOM) and their basic
management.
Recognize when to refer the patient to the concerned speciality.
Discuss the management of OTITIS MEDIA (CSOM).
Describe the need of surgery and when to refer patient to the relevant specialty
668
5. Ent 2 Ent 5 DISEASES OF INNER EAR
Diagnose the clinical presentation of diseases of inner ear and basics of

management.
Enlist appropriate investigations for inner ear problem
Distinguish inner ear diseases.
Describe when to refer the patient.
6. Ent 2 Ent 6 ALLERGIC, INFLAMMATORY & NEOPLASTIC DISEASES OF THE

NOSE-1
Recognize the clinical manifestation of Allergic, inflammatory and Neoplastic diseases

of the nose and to be able to request appropriate investigations
Interpret the lab investigation for basic management.
Enlist the indications of surgery and when to refer the patient.
Discuss the normal structures on CT scan of nose and Para nasal sinus .
Identify the common pathology on CT scan.
7. Ent 2 Ent 7 ALLERGIC, INFLAMMATORY DISEASES OF THE NOSE-2
RHINOSINUSITIS (ACUTE AND CHRONIC) :
Recognize the clinical manifestation of Acute and chronic sinusitis and Fungal
infections and to be able to request appropriate investigations
Interpret lab investigation for basic management.
Enlist the indications of surgery and when to refer.
8. Ent 2 Ent 8 EPISTAXIS:
Enlist the common causes of epistaxis ,its first Aid management and steps in cases of
uncontrolled epistaxis.
Recognize the clinical manifestations Malignancies of Nose and PNS with basic
principles of management
Interpret relevant investigations, understand indications of specialist referral.
Describe the basic principles of management.
9. Ent 2 Ent 9 NASOPHARYNX
Diagnose
o Adenoids
o Juvenile Nasopharyngeal Angiofibroma
o Nasopharyngeal Carcinoma
Discuss the clinical manifestations of disease.
669
Distinguish nasopharyngeal diseases.
Interpret investigations.
Recognize the need of surgery and when to refer
10) Ent2: Ent : 10 NASAL BONE FRACTURE : NOSE 3
Diagnose Nasal bone fracture.

Describe presentation, Principles of management and indication of surgery.
Discuss the differential diagnosis of Nasal Obstruction .
Differentiate between CSF Rhinorrhea and Allergic Rhinitis.
Recognize when to refer.
11) Ent2: Ent 11 ORAL CAVITY:
Explain the applied anatomy, inflammatory and ulcerative conditions
Recognize the clinical manifestations and to be able to request appropriate
investigations and know the basic management .
Diagnose the premalignant conditions and risk factors associated with them.
Enlist the indications of surgery and when to refer.
12) Ent2: Ent : 12 NEOPLASTIC CONDITIONS
Recognize the clinical manifestations of neoplastic conditions of oral cavity and

squamous cell carcinoma.
Enlist the appropriate investigations
Enumerate the basic management, recognize the indications of surgery and when to
refer.
Enlist the common factors and causes of Oral Cancer.
Describe the need of Neck Dissection
13) Ent2: Ent : 13 DISORDERS OF SALIVARY GLANDS
Explain surgical anatomy and applied physiology of salivary glands .

Describe its inflammatory conditions.
Recognize the clinical manifestations and be able to request appropriate investigations
and know the basic management.
Recognize the indications of surgery and when to refer.
Describe the knowledge of classification and distribution of salivary glands.
Discuss the knowledge of most common neoplastic lesions of salivary glands
Enumerate the knowledge of surgical procedures performed for salivary gland
diseases and their common complication
670
14) Ent2: Ent : 14 OROPHARYNX
Explain the applied anatomy.

Describe Tonsillitis.
Recognize the clinical manifestations of Tonsillitis and Pharyngitis and be able to
request appropriate investigations, its basic management and its complications .
Describe the D/D of Acute Tonsillitis and Acute Pharyngitis.
Recognize the indications of surgery and when to refer.
15) Ent2: Ent : 15 HYPOPHARYNX
Explain Plummer Vinson Syndrome

Diagnose Head and Neck spase infections .
Identify significance and risk factors related to Plummer Vinson Syndrome.
Describe brief knowledge of neck space infection specific in this space
Recognize the clinical manifestation of diseases and disorders and be able to request
appropriate investigations .
Discuss its basic management, recognize the indications of surgery and when to
refer.
16) Ent2: Ent : 16 DISEASES OF LARYNX
Explain the applied anatomy and physiology of larynx.

Diagnose acute and chronic inflammation of larynx .
Describe vocal nodules and vacal polyp.
Give the knowledge of basic treatment of laryngeal diseases .
Discuss the management of laryngeal pathologies.
Recognize the clinical manifestation of diseases and disorders and be able to request
appropriate investigations .
Describe the basic management, recognize the indications of surgery and when to
refer.
17) Ent2: Ent : 17 LARYNGEAL PARALYSIS AND CARCINOMA OF LARYNX:
Recognize the clinical presentation .

Discuss the management of carcinoma of larynx .
Enumerate about post operative care of laryngectomised patients and techniques of
their rehabilitation especially regarding speech.
Describe basic management, recognize the indications of surgery and when to refer.
671
18) Ent2: Ent : 18 STRIDOR, FOREIGN BODIES IN AIRWAY ,TRACHEOSTOMY:
Recognize the clinical presentations of stridor, foreign bodies in airway and

tracheostomy.
Should be able to identify the need of tracheostomy
Discuss the immediate management of foreign body larynx.
Explain the basic management.
Identify the indications of surgery and when to refer.
19) Ent 2: Ent : 19 OESOPHAGEAL DISORDERS:
Describe the applied anatomy and physiology .

Diagnose Dysphagia and Neoplastic Conditions .
Enumerate the clinical manifestation of oesophageal disorders
Explain its basic management.
Identify the indications of surgery and when to refer.
Discuss the indications and complications of Oesophagoscopy.
20) Ent2: Ent : 20 HEAD AND NECK:

Describe the surgical anatomy of triangles of neck and contents.
Identify the mid line swelling of Neck (congenital ,inflammatory and neoplastic
conditions).
Recognize the lateral swellings of Neck (congenital ,inflammatory and neoplastic
conditions).
Enumerate the clinical manifestations.
Discuss the D/D of neck swelling involving the anatomical site .
Diagnose the basic management, recognize the indications of surgery and when to
refer.
ETHICS
1) Ent 2: Eth 1 MEDICAL ETHICS: Describe bioethics,medical ethics,practical ethics.
2) Ent 2: Eth 2 DECISION MAKING CAPACITY: Describe types of informed consent.
3) Ent 2: Eth 3 DESCRIBE RESEARCH ETHICS: Describe Ethics.
4) Ent2: Eth4 PRIVACY: Describe respect for Autonomy,Privacy,and its types define
Confidentiality.
5) Ent2: Ent 5 THE RIGHTS OF PATIENT: Describe Human rights ,the rights of the patient
, its importance and describe the duties of physicians.
672
SCANERIO BASE LEANING
SBL 1:
Discuss CSOM with cholesteatoma.
Enumerate the factors led you to the diagnosis.
Describe Cholesteatoma.
SBL 2
Discuss the peritonsillar abcess.
Explain the etiological factors.
Enlist the optimum treatment options which can be offered.
OTOSCOPY (AUROSCOPY)
Introduction/Rationale
Otoscopy is a skill which is commonly required in the evaluation of
ear problems. An Otoscope is used to visualize the ear canal and
tympanic membrane to rule out any abnormal conditions that might
require further evaluation or treatment.
AT the end of a session students should be able to:-
1. Identify different parts of an Otoscope.
2. Demonstrate correct technique of otoscopy
3. Recognize normal External auditory canal (EAC) and tympanic
membrane(TM).
4. Identify at least 5 different abnormalities of EAC & TM.
Cerumen in auditory canal
Serous otitis media
Chronic otitis media with large perforation.
Cholesteatoma
Tympano- sc lerosis
673
SUBJECT/TOTAL X ROUND OFF

WEEKS/HOURS 1st 2nd 3rd TOTAL
60
2
ANATOMY 1 - - 1 1.8
2
PHYSIO 1 - - 1 1.8
4
PHARMA. - 1 1 2 3.7
4
PATHO - 2 - 2 3.7
43
CLINICAL 7 8 8 23 43.1
ENT 6
1.5 1.5 3 5.6
EXAMINATION
SKILL LAB 1.5 1.5 3 3.7 4
ETHICS - - 7 7 8.7 9
SBL 3 3 6 7.5 7
TOTAL 15 17 16 48 79.6 80
674
ENT-2 MODULE
(SEMESTER-VII / VIII)
THEORY

SEMESTER
ATP 25
EXAM
PAPER-I 80%
One best Questions
20
based on CBL
Total 100
MODULE EXAM
EMQs 10
ATP 20
MODULE PAPER 20%
One best Questions
20
based on SBL
Total 100
STRUCTURED VIVA

SUMMATIVE
ASSESMEN
SEMESTER
EXAM
See Semester
PAPER-IV-A Structured viva
T
Assessment Plan
ASSESSMENT TOOLS
Structured Feedback
ASSESSMENT DURING SBL SESSION Given to the Student by
Facilitator
NOTE: Paper II & IV-B of Semester-7 Examination are Based on Orthopadics-2 Module.
Paper III & IV-C of Semester-7 Examination are Based on Redroductive Syst.-2 Module.
675
CREDIT HOURS
SEMESTER VII/VIII
ENT-2 MODULE
Paper-I 3
ENT-2
Paper- IV-A 1.5
676
ORTHOPAEDICS AND TRAUMAMODULE
Code: (ORT 02)
Semester:VII
Fourth Year MBBS
677
Spiral Sem. Modules

II

IV
8 week Excretory System System 4 week
4 Week
wks
Second th
Spiral th
Trauma, 6 week
3 week 8 Weeks
/ Burns 2 wk
Weeks
th
th
PARALLEL THEMES:
678
Module Committee for Spiral 02:
Prof. DrSalahuddinAfsar, Professor of Medicine, DUHS.
Prof. Dr. NaheedKhan ,Professor of Ophthalmology, DUHS.
Dr. Maratib ,Professor of Orthopedic, DUHS.
Dr. YousufYahya,Assistant Professor of Pediatrics, DUHS.
Dr. Fawad Sheikh,Lecturer Pharmacology department DUHS.
Dr. Naseem Ahmed Sheikh,Assistant Professor of Pathology, DUHS
Dr RukhsanaRubeen, Associate Professor of Biochemistry, DUHS
MODULE IMPLEMENTATION BY:

Module Chief Coordinator: DrNaheed Khan
Module Coordinator:
DR. SAIMA RASHID
Documented by:
DR SAIMA RASHID
Reviewed by:
Modular committee
679
RATIONALE:
The Orthopedics module provides the student with the knowledge regarding common bone
and joint problems. The diseases involving this system include congenital disorders,
infections, acute and chronic osteomyelitis, bone tumours, metabolic diseases of bone and
degenerative disorders. A major component of this module as trauma related disorders. A
medical graduate after qualification, will be expected to manage orthopedics related trauma
and skill required for management of the injuries in the acute phase are essential for a
doctor.
The Locomotor module in the basic sciences cycle prepares the student by providing the
necessary knowledge of anatomy and physiology of the structures of the limb. This clinical
cycle module dwells on this knowledge and prepares the student by providing the principles
of radiological diagnosis and management of orthopedic diseases and trauma.
1. Understand the normal and abnormal structures and functions of skeletal
system and joints.
2. Interpret the biochemical changes in the body related to the bones with
reference of some common mineral metabolic disorders.
3. Take history and perform a satisfactory physical examination of the
musculoskeletal system.
4. Describe normal changes that occur in skeletal system functioning from
infancy to old age.
5. Formulate an appropriate plan for evaluating patients with bone related
conditions, signs and symptoms to achieve a reasonable differential
diagnosis and to develop an investigative and management plan.
6. Select the imaging techniques involved n the diagnosis of bone related disorders
and tumors
7. Diagnose, manage and prevent common skeletal system and joints

diseases.
680
ATP
BCQS, SEQS EMQS
WRITTEN ASSESS
DIGITAL LIBRARY
SELF STUDY
TUTORIALS
PRACTICAL
LECTURES
SKILL LAB
LIBRARY
VIVA
SBL
ORT2 Ane1 1
Development of skeletal *
Review normal
EMBRYOLOGY system Three germ layers
spine +hip joint ,concept
*
anatomy and of ossification
physiology of bones
and joints.
ANATOMY ORT2 Ang1Revisit: 1

Morphology of bones * *
types of cartilage
epiphysis + blood supply
applied
ORT2Bio1Revisit of Ca, 1.5 *

BIOCHEMISTRY Phosphate Vit D
metabolism *
ORT 2 Pth1 Classification 1.5
PATHOLOGY
of bone disorders *
(Practical)
*
ORT2Bio2Parathyroid 1.5
BIOCHEMISTRY
Hormone *
ORT2Sbl 1 1.5
SBL
Bone Metabolic Disorders * * *
ORT 2 Ane2 1.5 * * *
EMBRYOLOGY
Discuss and identify related to skeletal system
the common (Absence of bone,
congenital supranumerary,
anomalies of bones Syndactyly (Dwarfism).
681
and joints 1.5
RADIOLOGY
ORT 2
Rad1RADIOLOGY/ORTHO
* * *
Congenital abnormalities
of bone & skeletal System
Diagnosis &its
management.
ORT 2 Ped 1 Checklist at
Birth ,Congenital
1.5 * *
dislocation of hip
PEADS
ORT 2 Ped 2 Deformities, 1 * *

leg calf perthes disease,
scoliosis, club foot, slipped
capital femoral epiphysis.
Achondroplasia
ORT 2 Pth2Developmental
Abnormalities in bone 1.5 * *
PATHOLOGY cells, bone matrix and
structures (2 lec)
ORT 2 Med1
1.5
* *
Describe the Diagnosis and
diseases associated MEDICINE management of
with Defects in osteoporosis and
osteomalacia
Metabolic pathways
like Osteoporosis
PHARMACOLOGY
ORT 2 Pha1Drug
Management of 1.5 * *
Osteoporosis
&osteomalacia
`
Describe the RADIOLOGY
ORT2 Rad2
2 * * *
Osteoporosis,Rickets
pathogenesis of (Practical)
OSTEOPOROSIS
PATHOLOGY
ORT 2Pth3 * *
Lab inv of
(TUTORIAL) 2
Osteoporosis,Rickets and
Osteomalacia
2
SBL
ORT2Sbl 2 Osteoporosis * * *

Differentiate the BIOCHEMISTRYY
ORT2bio3 Modeling &
remodeling 1 * *
different diseases
associated with
MEDICINE
abnormal mineral ORT 2 Med2Clinical
features, Diagnosis and 1 * *
hemostasis including
Management of
clinical features,
Hyperparathyroidism&Hy
differential diagnosis poparathyroidism
and management of
Rickets ORT2Med3
&Osteomalacia MEDICINE Diagnosis and 1.5 * *
Management of
a. Rickets &Osteomalacia Osteoporosis and
b. Hyperparathyroidism Osteomalacia
682
c.Renalosteodystrophy ORT 2 Ped3Clinical
features, differential 1.5 * * *
PEADS
diagnosis and
management of Rickets

PHARMACOLOGY
ORT 2 Pha2Drug
Management of 1.5 * *
Osteoporosis
&osteomalacia
2LEC
PHARMACOLOGY ORT 2 Pha3 2
TUTORIAL * *
Osteoporosis
ORT2Sbl 3 2
SBL Osteomalacia * * *
ORT 2 Ort 1 1.5
Types ,classification and * * *
Classify different
Fractures Types, management of fractures
Classifications&
Managements of
ORT 2 Ort 2 1.5
fractures and know the
Management of Fractures * *
healing process
of Upper limb
ORT 2 Ort 3 1.5
Management of Fractures * *
of Lower limb
ORTHOPEDICS ORT 2 Ort 4 1.5

Spinal injuries * * *
ORT 2 Ort 5 1.5
* *
Healing problems
delayed union and
nonunion
ORT 2 Ort 6 1
Management of fractures, * *
different techniques
PATHOLOGICAL ORT 2 Pth4
TUTORIAL Pathological Fractures 2 * *
ORT2Sbl 4
SBL 2 * * *
Fractures
ORT 2 Pth 5
PATHOLOGY Type, classification, 1 * *
Pathogenesis of
osteomyelitis
ORT 2 Ort 7
Classify ORTHOPEDICS Management of acute 1.5 * *
Osteomyelitis osteomyelitis
ORT 2 Ort 8 1.5
Management of chronic * *
osteomyelitis
683
ORT 2 Pha 4 1.5
PHARMACOLOGY Drug management of * *
osteomyelitis
ORT 2 Rad 3 1
RADIOLOGY Metabolic skeletal lesions *
ORT 2 Pth 6 2
PATHOLOGY Lab Inv of Osteomyelitis * *
TUTORIAL
ORT 2 Pha 5 2
PHARMACOLOGY Tutorial of Osteomyelitis * *
TUTORIAL
ORT 2 Sbl 5 1.5

SBL Osteomyelitis * * *
ORT2Pth7 1
PATHOLOGY WHO classification of * *
Classify tumors of
bone tumors 2Lec
bone
ORT 2 Ort 9 1
ORTHOPEDICS Management of Benign * *
bone tumors
1lec
ORT 2 Ort 10 1.5

Management of malignant * *
bone tumors 2
lec
ORT 2 Rad 4
RADIOLOGY Imaging techniques * * *
1.5
involved in diagnosis of
bone tumors (X -RAY )
ORT2Pth8
PATHOLOGY Histopathology of Bone 2 * * *
PRACTICAL Tumors
Pathology ORT2Pth9
Tutorial tumor markers 2 * *
SBL ORT2Sbl 6
Bone Tumors 2 * * *
ANATOMY ORT2Ang3 1
Classify types of Revisit of Anatomy * *
arthritis regarding joints (synovial
membrane ,fluid )
emphasis on cartilage,
synovial lining, capsule
ligaments
MEDICINE ORT2Med4 1.5

How to approach with * *
arthritis & clinical features
and Diagnosis
ORT 2Pth10 1
PATHOLOGY ARTHRITIS * *
684
ORT 2 Ort 11
ORTHOPAEDIC Back pain * *
ORT 2 Ort 12
Diagnosis and * *
1.5
management of
OSTEOARTHRITIS
Discuss the ORT2Pha6
pharmacokinetics, PHARMACOLOGY NSAIDS * *
drug interactions,
contraindications
ORT 2Ped4
PEADS An approach to child with 1
* *
arthritis
ORT2Med5 1
MEDICINE Diagnosis and * *
Approach to a management of
patient with Rehumatoid Arthritis
arthritis
ORT2Pha7
PHARMACOLOGY DMARDS 1 and * *
DMARDS 2
ORT 2 Pth11 1
Pathology Clinical implication of *
Tutorial synovial fluid in various
forms of arthritis *
Pharma ORT2Pha8 1
Practical Tutorial Rx of OA * *
ORT2Bio4 1.5
Biochemistry Synovial Fluid * *
Practical Composition
ORT 2 Ort 18 1
SBL ARTHRITIS * * *
ORT2Bio5 1.5
BIOCHEMISTRY Revisit uric acid and * *
pyrophosphate
metabolism and
relationship to kidney
function
ORT2Med6
MEDICINE Diagnose and manage 1.5
* *
patient with GOUT
ORT2Pha9 1
PHARMACOLOGY Drugs used in Gout * *
PHARMACOLOGY ORT2Pha10 2
TUTORIAL TUTORIAL RX OF RA * *
ORT 2 Pth12 2
PATHOLOGY Crystals in Synovial fluid/ * *
TUTORIAL Joints
ORT 2 Pth13 2
PATHOLOGY Histo-pathological Slides * * *
PRACTICAL of joint disorders
685
SBL
ORT2Sbl 7
Gout
2
* * *
ORT 2 Med7
MEDICINE Clinical features, diagnosis *
and management of 1
patient with sero-
Discuss autoimmune negative
*
disorders spondyloarthropathies
ORT 2 Med 8
MEDICINE Clinical features and * *
diagnosis and 1.5
management of SLE
ORT 2 Med9
Clinical features and * *
diagnosis and
MEDICINE management of systemic
sclerosis and polymyositis
1.5
and dermatomyositis
ORT2Pth14 1.5
PATHOLOGY Histopathology Organ * *
TUTORIAL system changes in SLE
ORT 2 Pth15LAB INV of 1.5

PATHOLOGY SLE * *
PRACTICAL
ORT 2 Sbl 8 1.5

SBL * * *
SLE
ORT 2 Pth 16 1
PATHOLOGY Soft tissue tumors & * *
Describe different tumor like conditions
types of soft tissue
disorders involving
the limbs and
ORT 2 Pth 17 1.5
Avascular Necrosis
PATHOLOGY Skeletal muscles disorders * *
ORT 2 Ped 5 1.5
PEADS Short stature; endocrine, * *
metabolic and other
related disorders
ORT2Ped6 1
PEADS Muscular Atrophies and * *
Dystrophies
ORT2Ort13 1.5
Discuss soft tissue ORTHOPAEDICS Soft tissue disorders of * *
limbs
tumors
ORT2Pth18 1.5
PATHOLOGY Histopathology of soft * *
PRACTICAL tissue tumors
686
ORT2Pth1 9 1
PATHOLOGY Overview of blood /lab * *
TUTORIAL findings in bone and joint
disorders
SBL ORT2Sbl 9 1
Soft Tissue Tumors * * *
ORT 2 Com 1 1
Introduction to * *
Occupational health
Aims, Objectives,
Functions.
ORT 2 Com 2 1
Air Pollution * *
ORT 2 Com 3 1
Water Sources, Pollution * *
ORT 2 Com 4 1
Water Quality Indicators * *
and purification
ORT 2 Com 5 1
Housing and Radiation * *
Community ORT 2 Com 6 1
Medicine Nuclear Medicine * *
ORT 2 Com 7 1
Sports Medicine * *
ORT 2 Com 8 1
(tutorial) * *
Control and prevention of
occupational diseases .
ORT 2 Com 9
(tutorial) 1 * *
Control of occupational
hazards
ORT 2 Com 10
(tutorial) * *
Disposal of water
687
ORTHOPAEDIC MODULE
TIME TABLE
FIRST WEEK
Days 8:30 to 9:30 9:30 to 10:30 10:45 to 1:00 1:30 to 3:00
ANATOMY EMBRYOLOGY
Development of skeletal Biochemistry
Revisit: Morphology of bones Revisit of Ca,
system Three germ layers
types of cartilage epiphysis + Phosphate Vit D
1 spine +hip joint ,concept of Clinical Posting
blood supply applied NAME OF
ossification
NAME OF FACULTY
VENUE VENUE
VENUE
EMBRYOLOGY COMMUNITY
RADIOLOGY/ORTHO
Congenital anomalies MEDICINE
Congenital abnormalities of
related to skeletal system
bone & skeletal System Air Pollution
2 (Absence of bone,
supernumerary, syndactyly, Diagnosis & management Clinical Posting NAME OF
Dwarfism)
NAME OF FACULTY
VENUE VENUE VENUE
PATHOLOGY
PEADS
Developmental
Checklist at Birth ,Congenital
Abnormalities in bone cells,
dislocation of hip
3 bone matrix and structures Clinical Posting
VENUE
VENUE
PATHOLOGY MEDICINE PHARMACOLGY

Developmental Abnormalities Diagnosis anedmanagement Drug
in bone cells, bone matrix and Management of
of osteoporosis and
4 structures Clinical Posting Osteoporosis
osteomalacia &osteomalacia
NAME OF FACULTY
NAME OF FACULTY NAME OF
VENUE VENUE FACULTY
VENUE
688
ORTHOPAEDIC MODULE
SEMESTER-VII:
THEME OF THE WEEK: BONE METABOLISM/BONE REPAIR
WEEK: 2
Days 8:30 to 9:30 9:30 to 10:30 10:45 to 12:30 1:30 to 3:00

Medicine
PHYSIOLOGY Diagnosis ORTHOPEDICS
Modeling & Remodeling anedmanagement of Types, classification
NAME OF FACULTY osteoporosis and Clinical Posting And management of fractures
1
osteomalacia NAME OF FACULTY
VENUE
VENUE
PHARMACOLGY
ORTHOPEDICS Medicine
Drug Management of Management of
2 Clinical features, diagnosis and
Osteoporosis Fractures of Upper management of
&osteomalacia Limb Clinical Posting
Hyperparathyroidism&Hypoparathyroidism
VENUE VENUE VENUE
8:30-10:00
BIOCHEMISTRY: Affect Of Parathyroid Hormone On CM
Bone Mineral Metabolism=A1 +A5 VENUE Introduction To Occupational Health
3 Clinical Posting
PATHO: Classification of Bone Disorders=A2 VENUE NAME OF FACULTY
VENUE
C/M=A3 VENUE
SBL: A4 VENUE
BIOCHEMISTRY: Affect Of Parathyroid Hormone
PEDIATRICS
On Bone Mineral Metabolism =A2 VENUE
Clinical features, differential diagnosis and
PATHO: Classification of Bone management of Rickets
4 Disorders=A3+A1VENUE. Clinical Posting
NAME OF FACULTY
C/M=A4 VENUE
VENUE
SBL: A5 VENUE
BIOCHEMISTRY Affect Of Parathyroid Hormone On
Bone Mineral Metabolism =A3 VENUE
5 PATHO: Classification of Bone Disorders=A4 VENUE Clinical Posting

C/M=A5+A2 VENUE
SBL: A1 VENUE
BIOCHEMISTRY Affect Of Parathyroid Hormone On Orthopedics
Bone Mineral MetabOlism =A4 VENUE Management of Fractures of lower limb
NAME OF FACULTY
6 PATHO: Classification of Bone Disorders=A5 VENUE Clinical Posting
C/M=A1 VENUE VENUE
SBL: A2 +A3 VENUE
689
ORTHOPAEDIC MODULE
SEMESTER-VII:
THEME OF THE WEEK:OSTEOMYELITIS
WEEK: 3
Days 8:30 to 9:30 9:30 to 10:30 10:00 to 12:30 1:30 to 3:00
PATHOLOGY
PEDIATRICS ORTHOPEDICS Type, classification,
Deformities, leg calf perthes
Pathogenesis of osteomyelitis
1 disease, scoliosis, club foot, Healing problems
CLINICAL POSTING NAME OF FACULTY
slipped capital femoral delayed union and non
epiphysis. Achondroplasia union
VENUE VENUE
RADIOLOGY ORTHO ORTHO
Metabolic Skeletal Lesions Acute osteomyelitis Chronic Osteomyelitis
VENUE VENUE VENUE
8:30 AM - 10.00 AM
PHARM:
ROLE OF RADIOLOGY: Osteoporosis,
Drug management of
Rickets A1+ A4 NAME OF FACULTYVENUE
osteomyelitis
PATHOLOGY TUTORIAL NAME OF FACULTY
3 CLINICAL POSTING
Lab investigations of Osteoporosis, Rickets
&OsteomalaciaA2 + A5, NAME OF FACULTYVENUE
VENUE
SBL, A3 NAME OF FACULTY
, ATA HALL
ROLE OF RADIOLOGY:Osteoporosis, Rickets A2 + A5,
VENUENAME OF FACULTY C/M
PATHOLOGY TUTORIAL Water sources and pollution
Lab investigations of Osteoporosis, Rickets NAME OF FACULTY
4 &Osteomalacia A3 VENUE NAME OF FACULTY CLINICAL POSTING
VENUE
SBL A4 + A1, VENUE NAME OF FACULTY
ROLE OF RADIOLOGY:
Osteoporosis, Rickets A3 VENUE
NAME OF FACULTY
PATHOLOGY TUTORIAL
Lab investigations of Osteoporosis, Rickets
5 CLINICAL POSTING
&Osteomalacia A4+A1, VENUE
NAME OF FACULTY
SBL= A5 + A2, VENUE NAME OF FACULTY
6
PUBLIC HOLIDAY
690
ORTHOPAEDIC MODULE
SEMESTER-VII:
THEME OF THE WEEK:GOUT
WEEK: 4
10:30
Days 8:30 to 9:30 9:30 to 10:30 1:30-3:00
1:30
PEADS ORTHO DMARDS 1

How to approach a patient with BACK PAIN Clinical NAME OF FACULTY
1
arthritis NAME OF FACULTY Posting
VENUE VENUE
BIO
C/M
Revisit uric acid and DMARDS2 Clinical
Water sources and Purification
2 Pyrophosphate metabolism and NAME OF FACULTY Posting
NAME OF FACULTY
relationship to kidney function VENUE
VENUE
CM: Control and Prevention of occupational Diseases

Gp= A1+ A5 NAME OF FACULTY VENUE
MED
PATHOLOGY TUTORIAL: Lab investigation of Osteomyelitis Gp= A2 Clinical Diagnosis and management of
3 NAME OF FACULTY VENUE Posting Rehumatoid arthritis
FM: Spinal Injuries Gp= A3 NAME OF FACULTY VENUE NAME OF FACULTY VENUE
SBL Gp=A4, NAME OF FACULTY VENUE
4
PUBLIC HOLIDAY
CM: Control and Prevention of occupational DiseasesGp= A3
5 Clinical
FM:Spinal Injuries Gp= A5+A2 NAME OF FACULTY VENUE Posting
SBL Gp=A1 NAME OF FACULTY VENUE
CM: Control and Prevention of occupational Diseases
Gp= A4 NAME OF FACULTY VENUE
PATHOLOGY TUTORIAL: Lab investigation of Osteomyelitis Gp= A5 MED:
NAME OF FACULTY VENUE Clinical Diagnose and manage patient with
6
Posting GOUT
FM: Spinal Injuries Gp= A1, NAME OF FACULTY VENUE NAME OF FACULTY VENUE
SBL Gp= A2+A3 NAME OF FACULTY VENUE
691
ORTHOPAEDIC MODULE
SEMESTER-VII:
THEME OF THE WEEK:ARTHRITIS
WEEK: 5
Days 8:30 to 9:30 9:30 to 10:30 10:30 1:30 1:30-3:00

ANATOMY PATHOLOGY
Revisit Arthritis (Pathophysiology of MED
Gross features of joints (synovial Clinical features, diagnosis and
different types of OA/RA ) Clinical
1 membrane ,fluid ) emphasis on management of patient with sero-
NAME OF FACULTY Posting
cartilage, synovial lining, capsule negative spondyloarthropathies
ligaments VENUE NAME OF FACULTYVENUE
PHARM CM MEDICINE
NSAIDS I Housing And Radiation How to approach with patient
NAME OF FACULTYVENUE NAME OF FACULTYVENUE Clinical of arthritis
2
Posting (clinical features and Diagnosis)
NAME OF FACULTY
VENUE
CM: Disposal of Waste A1+A5 NAME OF FACULTYVENUE
PHARM
NSAIDS II
BIO : SYNOVIAL FLUID COMPOSITION A2 NAME OF FACULTYVENUE
3 NAME OF FACULTYVENUE
Clinical
PATHOLOGY TUTORIAL: Clinical Implication of synovial fluid in various forms Posting
of Arthiritis. A3 DR IKRAMULLAH VENUE
SBL A4 NAME OF FACULTYVENUE
CM: Disposal of Waste A2 NAME OF FACULTYVENUE ORTHO

Diagnosis and management of
BIO : SYNOVIAL FLUID COMPOSITION A3+A1 NAME OF FACULTY
Clinical osteoarthritis
VENUE
4 Posting NAME OF FACULTYVENUE
PATHOLOGY TUTORIAL: Clinical Implication of synovial fluid in various forms
of Arthiritis. A4 NAME OF FACULTYVENUEVENUE
SBL A5 NAME OF FACULTYVENUE
10:00-12:30 PM
CM: Disposal of Waste A3 NAME OF FACULTYL VENUEVENUE
BIO: SYNOVIAL FLUID COMPOSITION A4, NAME OF FACULTYVENUE

5
PATHOLOGY TUTORIAL: Clinical Implication of synovial fluid in various forms
Clinical Posting
of Arthiritis. A5+A2 NAME OF FACULTYVENUE
SBL A1 NAME OF FACULTYNAME OF
FACULTYVENUE
CM: Disposal of Waste A4 NAME OF FACULTYL VENUE
PHARM
BIO: SYNOVIAL FLUID COMPOSITION A5 NAME OF FACULTYVENUE Drugs used in Gout
Clinical
6 PATHOLOGY TUTORIAL: Clinical Implication of synovial fluid in various forms NAME OF FACULTY
Posting
of Arthiritis. A1 NAME OF FACULTYVENUEVENUE VENUE
SBL A2+A3 NAME OF
FACULTYVENUE
692
ORTHOPAEDIC MODULE
SEMESTER-VII:
THEME OF THE WEEK: Soft Tissue Disorders
WEEK: 6
Days 8:30 to 9:30 9:30 to 10:30 11:00 12:45 1:30-3:00
CM: Control and Prevention of occupational DiseasesGp= A2
Med:
PATHOLOGY TUTORIAL: Lab investigation of Osteomyelitis Gp= A3
1 + A1 NAME OF FACULTYVENUE CLINICAL Clinical features and diagnosis and
POSTING management of SLE
FM:Spinal Injuries Gp= A4 NAME OF FACULTYVENUE
SBL Gp=A5 NAME OF FACULTYVENUE
CLINICAL
POSTING Med
Ortho Clinical features and diagnosis and
Patho:
Soft tissue disorders management of systemic sclerosis
2 Skeletal muscles disorders
NAME OF FACULTY and polymyositis and
VENUE dermatomyositis
CM TUTO : TRAVEL MEDICINE NAME OF FACULTY CLINICAL

Gp= A1+A5 VENUE POSTING
PATHOLOGY TUTO : LAB INV of SLE, DR. NAME OF FACULTYBGp= Patho:
A2VENUE Soft tissue tumors & tumor like
3
conditions
PHARMA TUTORIAL:Rx of OA and RA NAME OF FACULTYVENUEGp=
A3
SBL: BONE TUMORS NAME OF FACULTYGp= A4 VENUE
CM TUTO : TRAVEL MEDICINE NAME OF FACULTY CLINICAL

Gp= A2 ARAG POSTING
PATHOLOGY TUTO : LAB INV of SLE, NAME OF FACULTYVENUEGp= C/M

4 A3+A1 NUCLEAR MEDICINE
PHARMA TUTORIAL:Rx of OA and RA NAME OF FACULTYVENUE NAME OF FACULTYVENUE
VENUEGp= A4
SBL: BONE TUMORS NAME OF FACULTY= A5
VENUE
CM TUTO : TRAVEL MEDICINE NAME OF FACULTY

A3 VENUE
PATHOLOGY TUTO : LAB INV of SLE, NAME OF FACULTYVENUEGp=

5 A4 CLINICAL POSTING
PHARMA TUTORIAL:Rx of OA and RA NAME OF
FACULTYVENUEVENUEGp= A5+A2
SBL: BONE TUMORS NAME OF FACULTYGp= A1 VENUE
CM TUTO : TRAVEL MEDICINE NAME OF FACULTY

Gp= A4 VENUE 1
Peads:
PATHOLOGY TUTO : LAB INV of SLE, NAME OF FACULTYVENUEGp= CLINICAL Short stature; endocrine, metabolic
6 A5 POSTING and other related disorders
PHARMA TUTORIAL:Rx of OA and RA DR. SAUD VENUEGp= A1 NAME OF FACULTYVENUE
SBL: BONE TUMORS NAME OF FACULTYGp= A2+A3
VENUE
693
ORTHOPAEDIC MODULE
SEMESTER-VII:
THEME OF THE WEEK:BONE TUMORS
WEEK: 7
Days 8:30 to 9:30 9:30 to 10:30 10:30 12:45 1:30-3:00
PATHOLOGY:
PEADS: COMMUNITY MEDICINE
Muscular Atrophies and WHO classification of Sports Medicine
1 bone tumors
Dystrophies Clinical Posting NAME OF FACULTY
NAME OF NAME OF FACULTY VENUE
FACULTYVENUE
VENUE
PATHOLOGY: ORTHOPEDICS
RADIOLOGY
WHO classification of Management of
Imaging techniques involved in diagnosis
2 bone tumors Benign bone tumors Clinical Posting
of bone tumors
NAME OF FACULTY
VENUE
VENUE
VENUE
ORTHOPEDICS
ORTHOPEDICS
Management of
SPINAL INJURIES
3 malignant bone tumors Clinical Posting
NAME OF FACULTY
NAME OF FACULTY
VENUE
VENUE
Clinical Posting
4
Clinical Posting
5
6 MODULE TEST
694
LEARNING OBJECTIVES
At the end of the lecture the student should be able to:
ANATOMY
1. ORT 2 Ang1REVISIT: MORPHOLOGY OF BONES TYPES OF CARTILAGE
EPIPHYSIS + BLOOD SUPPLY APPLIED
Define bones, and its functions.
Classify the bones.
Describe the endochondral and intramembranous ossification.
Differentiate between different types of cartilage and know their locations.
2. ORT 2 Ang2GROSS FEATURES OF JOINTS (SYNOVIAL MEMBRANE

,FLUID ) EMPHASIS ON CARTILAGE, SYNOVIAL LINING, CAPSULE
LIGAMENTS
Enlist Types of joints
Describe ythe structure of synovial membrane and its functions
Describe the pathologies of joint
EMBRYOLOGY
1. ORT 2 Ane1Development of skeletal system , explain the three germ
layers of spine + hip joint and concept of ossification .
Development of skeletal system .

Explain three germ layers of spine +hip joint ,
Discuss the concept of ossification.
2. ORT 2 Ane2Congenital anomalies related to skeletal system.

(Absence of bone, Achondroplasia ,Supranumerary, Syndactyly,
Dwarfism).
Know the different congenital anomalies of limbs.

Enumerate the causes of abnormalities.
Describe the detail of Achondroplasia.
Know the genes associated with skeletal defects.
695
RADIOLOGY
1. ORT 2 Rad1CONGENITAL ABNORMALITIES OF BONE &SKELETAL
SYSTEM DIAGNOSIS & MANAGEMENT
Identify abnormalities in skeletal development, growth ,maturation and

modeling.
Diagnose the anomalies arising during fetal development, such as congenital
absence of a whole or part of a limb, supra-numerary digits in hand or foot, or
fused digit, they are obvious at the time of birth.
Describe its radiological findings.
2. ORT 2 Rad2RADIOLOGY (PRACTICAL)OSTEOPOROSIS.
IdentifyOsteoporosis on X-RAY.
Explain the diagnostic factors of osteoporosis.
Describe its differential diagnostic and identification points .
3. ORT 2 Rad 3METABOLIC SKELETAL LESIONS
Identifymetabolic skeletal lesionson X-RAY.

Explain the diagnostic factors of bone lesions.
Describe its differential diagnostic ,identification points.
4. ORT 2 Radio4IMAGING TECHNIQUES OF X-RAY IN BONE TUMORS.
Identifybone tumors on X-RAY.

Explain the diagnostic factors of bone tumors.
Describe its differential diagnostic ,identification points
BIOCHEMISTRY
1. ORT 2 Bio1 REVISIT OF CA, PHOSPHATE VIT D.
Explain the systemic regulation of calcium

Describe the bio chemical changes in calcium related disorders.
Evaluate the phosphate related disorders.
Explain the synthesis of Vitamin D-3.
Discuss osteomalacia and evaluate the clinical manifestation of osteomalacia.
696
2. ORT 2 Bio 2PARATHYROID GLANDS
Identify the morphology of parathyroid gland.

Explain the functions of parathyroid gland.
Discuss the calcium metabolism.
3. ORT 2 Bio 3MODELING & REMODELING
Explain the regulation of bone modeling and remodeling.

Enumerate the functions of parathyroid hormones
Discuss the systemic regulation of bone modeling and remodeling.
Under hormonal control of calcium.
Interpret role of Vitamin D and calcium absorption and its clinical co relation.
Evaluate the role of parathyroid hormone.
Describe the synthesis and regulation of parathyroid hormone.
Explain the regulation of calcitonin.
Discuss the influence of growth hormone andglucocorticoids.
4. ORT 2 Bio4SYNOVIAL FLUID COMPOSITION (PRACTICAL)

Explain thesynovial fluid composition.
Describe its biochemical composition.
Explain the synthesis of Vitamin D-3.
5. ORT 2 Bio5URIC ACID AND PYROPHOSPHATE METABOLISM
Revisit uric acid and pyrophosphate metabolism and relationship to kidney

function.
Explain their metabolic pathway.
PATHOLOGY
1. ORT 2 Pth1CLASSIFICATION OF BONE DISORDERS (PATHOLOGY PRACTICAL )

Classify different types of bone disorders.
Describe its pathogenesis.
2. ORT 2 Pth2DEVELOPMENTAL ABNORMALITIES IN BONE CELLS, BONE
MATRIX AND STRUCTURES. LECTURE (1)
Describe the different forms of bone cells And bone matrix
Explain bone remodeling.
697
3. ORT 2 Pth3DEVELOPMENTAL ABNORMALITIES IN BONE CELLS AND
BONE MATRIX.LECTURE (2)
Describe the different forms of bone cells And bone matrix

Explain bone remodeling
4. ORT 2Pth4LAB. INVESTIGATIONS OF OSTEOPOROSIS ,RICKETSAND

OSTEOMALACIA (TUTORIAL)
Enumerate the lab investigations Osteoprosis and Osteomalacia.

Explain the diagnostic factors of osteoporosis ,rickets and
osteomalaciaDiscussosteomalacia and rickets.
5. ORT 2 Pth5 PATHOLOGICAL FRACTURES (TUTORIAL)
Enumerate the causes of PATHOLOGICAL FRACTURES.

Explain the diagnostic factors regarding PATHOLOGICAL FRACTURES.Discussits
clinical features.
6. ORT 2 Pth6TYPE, CLASSIFICATION, PATHOGENESIS OF

OSTEOMYELITIS.
Classify different types of Osteomyelitis.

Describe the pathogenesis of Osteomyelitis.
Enlist different stages of articular tuberculosis.
Discuss the management.
7. ORT 2 Pth7LAB.INVESTIGATIONS OF OSTEOMYELITIS(TUTORIAL )
Enumerate the lab investigationsofOSTEOMYELITIS.

Explain the diagnostic factorsofosteomyelitis
Discuss Osteomyelitis
8. ORT 2 Pth8WHO CLASSIFICATION OF BONE TUMORS.
Enlist its WHO classification

Enumerate its incidence
Describe its histopathology.
Discuss its clinical findings
698
9. ORT 2 Pth9HISTOPATHOLOGY OF BONE TUMORS
Describe different types of Bone Tumors.

Explain the morphology and histopathology
Discuss the differential diagnosis
Describe the pathogenesis of Bone Tumors.
Discuss their clinical features.
10. ORT 2 Pth10TUMOR MARKERS (PATHOLOGICAL TUTORIAL)
Classify different types of tumor markers .

Explain their significance.
Discuss their clinical implications .
11. ORT 2 Pth11ARTHRITIS
Describe different types of Arthritis

Describe the causative factors and pathogenesis of Arthritis.
Discuss Juvenile idiopathic arthritis, Reiters Syndrome, Psoriatic arthritis
12. ORT 2 Pth12CLINICAL IMPLICATIONS OF SYNOVIAL FLUID(TUTORIAL)
Describe the Synovial Fluid Composition.

Explain its clinical importance.
13. ORT 2Pth13CRYSTALS IN SYNOVIAL FLUID(TUTORIAL)
Know the Crystals in Synovial Fluid.

Explain its clinical importance.
14. ORT 2 Pth14HISTOPATHOLOGICAL SLIDES OF JOINT DISORDERS
Describe the histopathology of joint disorders.

Describe the causative factors and pathogenesis of joint disorders.
Discuss its differential diagnosis
Explain the morphology and histopathology.
699
PEDIATRICS
1. ORT 2 Ped 1CHECKLIST AT BIRTH ,CONGENITAL DISLOCATION OF HIP.
Explain Anthropometrics.
Examine ,skin ,skull ,dimorphic features of eyes, ears, neck , chest , genitals
and foot .
Discuss the developmental dysplasia of hip and its complications.
2. ORT 2 Ped 2DEFORMITIES, LEG CALF PERTHES DISEASE, SCOLIOSIS,

CLUB FOOT, SLIPPED CAPITAL FEMORAL EPIPHYSIS AND
ACHONDROPLASIA.
Explain club foot, or congenital talipesequinovarus (CTEV)

Discuss postural TEV and structural TEV.
3. ORT 2 Ped 3CLINICAL FEATURES, DIFFERENTIAL DIAGNOSIS AND

MANAGEMENT OF RICKETS
Explain Rickets.
Discuss its Clinical features, differential diagnosis and management of
Rickets.
4. ORT 2 Ped 4APPROACH A CHILD WITH ARTHRITIS
Inquire about daily activities

Enlist sports limitation
Enumerate the degree of disability
Discuss the involvement of other body systems.
Explain fever, trauma,sorethroat,shifting of joint pain,rashes.
5. ORT 2 Ped 5SHORT STATURE, ENDOCRINE, METABOLIC ANDOTHER
RELATED DISORDERS.
Explain the causes of short stature, endocrine, metabolic and other related
disorders.
Describe Osteogenesisimperfecta,ProgressiveDiaphysi,sDysplasia,Marfans
Syndrome ,Achondroplasia and Refractory Rickets.
6. ORT 2 Ped 6MUSCULAR DYSROPHIES
Explain Progressive Muscular Dystrophy

Diagnose Duchenes MuscularDystrophy ,Beckers Muscular Dystrophy.
700
Discuss Emery Dreifuss Dystrophy,
FacioscapulohumeralDystrophy,ScapuloperonealSyndrome,Oculopharyngeal
Dystrophy.
How to evaluate Congenital Muscular Dystrophies,Myotonic Dystrophy,
Limb-Girdle Muscular Dystrophies ,Spinal muscular atrophy (SMA).
PHARMACOLOGY
1. ORT 2 Pha1DRUG MANAGEMENT OF OSTEOPOROSIS & OSTEOMALACIA
Explain the treatment of primary Osteoporosis&Osteomalacia .

Discuss the mode of action of drugs .
2. ORT 2 Pha 2 DRUG MANAGEMENT OF OSTEOPOROSIS & OSTEOMALACIA
Explain the treatment of secondary Osteoporosis&Osteomalacia .

3. ORT 2 Pha 3DRUG MANAGEMENT OF OSTEOPOROSIS & OSTEOMALACIA
Explain the treatment of primary and secondary Osteoporosis&Osteomalacia .

4. ORT 2 Pha 4 DRUG MANAGEMENT OF OSTEOMYELITIS
Explain about basics of bone regulation

Classify and know the causes of osteoporosis
Understand and interpret the bone chemistry and specific investigations
Explain the impact of osteoporosis on the health of the elderly
Know about available preventive and therapeutic options
5. ORT 2 Pha 5 DRUG MANAGEMENT OF OSTEOMYELITIS (TUTORIAL)
Explain about basics of bone regulation

Classify and know the causes of osteoporosis
Understand and interpret the bone chemistry and specific investigations
Explain the impact of osteoporosis on the health of the elderly
Know about available preventive and therapeutic options
701
6. ORT 2 Pha 6NSAIDS ( I and II)
Discuss the mode of action of Cytokines ,Cyclooxygenase and Prostaglandins.

Explain the role of acute and chronic inflammation as an initial response to tissue injury.
Discuss the mode of action of anti-inflammatory drugs by blocking the synthesis of
prostaglandins.
Explain their anti-inflammatoryeffects .
Describe its role for the treatment acute gouty arthritis and superficial thrombophlebitis.
Discuss its serious side effects.
7. ORT 2 Pha 7 DMARDS (I and II)
Describe the inflammatory ,metabolic and degenerative disorders .

Explain the mode of action of Penicililamine,Methotrexate,Hydrocortisone.
Describe the mode of action of cyclophosphamide,sulphasalazine ,corticosteroids.
Explain the mode of action Tumor necrosis factor -1 inhibitors
8. ORT 2 Pha 8 TREATMENT OF OSTEOARTHRITIS (TUTORIAL)
Discuss the mode of action of drugs.

Discuss the mode of action of anti-inflammatory drugs.
Describe its role for the treatment osteoarthritis .
Discuss its serious side effects
9. ORT 2 Pha 9 DRUGS USED IN GOUT
Enlist the drugs used in gout

Discuss the clinical features of gout.
Describe the treatment of gout.
Explain the mechanism of action , side effects and drug interaction and its
prevention of recurrent attacks of gout.
10. ORT 2 Pha 10 TREATMENT OF RHEUMATOID ARTHRITIS(TUTORIAL)
Discuss the mode of action of drugs.

Discuss the mode of action of anti-inflammatory drugs.
Describe its role for the treatment rheumatoid arthritis .
Discuss its serious side effects
702
ORTHOPAEDICS
1. ORT2 Ort 1TYPES ,CLASSIFICATION AND MANAGEMENT OF FRACTURES.
Restore the patient to optimal functional state

Prevent fracture and soft-tissue complications
Get the fracture to heal, and in a position which will produce optimal functional recovery
Rehabilitate the patient as early as possible.
2. ORT2 Ort 2MANAGEMENT OF FRACTURES OF UPPER LIMB
Explain the mechanism of fractures

Different types of fractures and their complications.
Different methods of management .
3. ORT2 Ort 3MANAGEMENT OF FRACTURES OF LOWER LIMB
Explain the mechanism of fractures

Different types of fractures and their complications.
Different methods of management .
4. ORT2 Ort 4SPINAL INJURIES
Describe the classification of Spinal Injuries .

Explain the causes
Explain ANTERIOR CORD SYNDROME ,CENTRAL CORD SYNDROME, BROWN-
SEQUARD SYNDROME
Discuss their treatment
5. ORT2 Ort 5HEALING PROBLEMS DELAYED UNION
Explain the delayed union.

Describe whole fibula transplantation.
Diagnose non -union.
Express visualization free fibular graft.
Discuss the management of union and nonunion.
6. ORT2 Ort 6MANAGEMENT OF FRACTURES, DIFFERENT TECHNIQUES.
Explain the types of fractures.

Discuss the management and treatment of Fracture.
Describe the complications
703
7. ORT2 Ort 7MANAGEMENT OF ACUTE OSTEOMYELITIS
Enlist types of acute osteomyelitis.

Interpret the causes.
Explain the role of anti biotics in acute osteomyelitis.
Explain the mode of action of different drug resistance penicillin.
Discuss the complications.
Describe bone tuberculosis and its principles of management
8. ORT2 Ort 8MANAGEMENT OF CHRONIC OSTEOMYELITIS
Enumerate the classification of chronic osteomyelitis.

Explain GiernyMader System.
Describe the pathogensis of chronic osteomyelitis.
Explain the etiology and investigations preceded of chronic osteomyelitis.
Discuss the management of chronic osteomyelitis.
Explain bordies abscess.
9. ORT2 Ort 9MANAGEMENT OF BENIGN TUMOURS
Explain history taking and examination.

Classify benign bone tumours at different ages.
Enumerate different symptoms of benign tumors.
Enlist staging of benign bone tumours.
Discuss the deformity complication and management of benign tumours.
10. ORT2 Ort 10MANAGEMENT OF MALIGNANT BONE TUMORS
Describe the different types of bone tumors .

Explain the chondroblastic tumors and Notochondral tumors
11. ORT2 Ort 11OSTEOARTHRITIS
Explain osteoarthritis as progressive softening &disintegration of articular

cartilage.
Discuss the pathogenesis of osteoarthritis.
Primary distribution ,sign and symptoms and its management.
12. ORT2 Ort 12BACKPAIN
Enlist the causes and prevalance of back pain

Describe Spondylothesis and Spondylosis
Discuss the Management and medication of back pain
704
13. ORT2 Ort 13SOFT TISSUE DISORDERS
Explain Rotator Cuff Tear.

Describe Impingement Syndrome.
Discuss Biceps Tendinitis ,Deltoid Contracture ,Olecranon Bursitis ,Carpal
Tunnel Syndrome.
Classify Impingement Syndrome, Trigger Finger Hallux ,
Valgus Hammer Toe ,ClawToes.
MEDICINE
1. ORT 2 Med 1DIAGNOSIS ANDMANAGEMENT OF OSTEOPOROSIS AND
OSTEOMALACIA.
To know about basics of bone regulation

To classify and know the causes of osteoporosis
To understand and interpret the bone chemistry and specific investigations
Show the impact of osteoporosis on the health of the elderly
To explain about available preventive and therapeutic options
2. ORT 2 Med 2 CLINICAL FEATURES, DIAGNOSIS AND MANAGEMENT OF

HYPERPARATHYROIDISM&HYPOPARATHYROIDISM .
Enumerate the causes of hyper and hypo-calcemia.

Understand osteomalacia and rickets
Explain the basic bone chemistry and their abnormalities.
Investigate the metabolic bone diseases .
Discuss its management.
3. ORT 2 Med 3 DIAGNOSIS ANDMANAGEMENT OF OSTEOPOROSIS AND

OSTEOMALACIA.
To know about basics of bone regulation

To classify and know the causes of osteoporosis
To understand and interpret the bone chemistry and specific investigations
Show the impact of osteoporosis on the health of the elderly
To explain about available preventive and therapeutic options
4. ORT 2 Med 4 ARTHRITIS
Describe different types of Arthritis

Describe the causative factors and pathogenesis of Arthritis
705
Explain Juvenile idiopathic arthritis, Reiters Syndrome, Psoriatic arthritis
5. ORT 2 Med 5 RHEUMATOID ARTHRITIS
Describe the causative factors and pathogenesis of RheumatoidArthritis.

Explain the morphology and histopathology.
Diagnose its management.
6. ORT 2 Med 6 DIAGNOSE AND MANAGE PATIENT WITH GOUT

Enlist the causative factors of Gout.
Describe the pathogenesis Gout
Explain Acute Gout,GoutyTrophi,Uric acid,
Discuss the clinical features and management of gout,
Enumerate the role of Colchicine,Corticosteroids,NSAIDs and Analgesics in gout.
Explain the treatment of Gout.
7. ORT 2 Med 7 CLINICAL FEATURES, DIAGNOSIS AND MANAGEMENT OF PATIENT

WITH SERO- NEGATIVE SPONDYLOARTHROPATHIES
Enlist different types of spondyloarthropathies.

Evaluate ankylosing spondylitis
Describe the clinical features diagnosis and management of patient with sero- negative
spondyloarthropathies.
8. ORT 2 Med 8 SYSTEMIC LUPUS ERYTHEMATOSUS
Define Epidemiology
Describe its pathophysiology
Diagnose the criteria for SLE
Enumerate its clinical features
Discuss its treatment and prognosis .
9. ORT 2 Med 9 SYSTEMIC SCLEROSIS,POLYMYOSITIS AND DERMATOMYOSITIS
Classify systemic sclerosis

Explain polymyositis and dermatomyositis
Define its epidemiology
Describe the diagnosis of systemic sclerosis, polymyositis and dermatomyositis
Discuss its treatment of systemic sclerosis, polymyositis and dermatomyositis
706
COMMUNITY MEDICINE
1. ORT 2 Com1INTRODUCTION TO OCCUPATIONAL HEALTH
Define occupational health

Describe relationship between effect of working and working environment.
Describe the influence of state of the health of worker on his ability
Discuss protection of worker from adverse factor of health
Classify occupational diseases i.e. pneumoconiosis
2. ORT 2 Com 2 DEFINE AIR POLLUTION
Describe some actions they can personally do to improve air quality

Explain why air quality is of special concern to the area
Describe a remedy to the air pollution problems
Define air pollution
Identify the criteria pollutants
3. ORT 2 Com 3 WATER SOURCE POLLUTION
Enlist the types of water pollution.

Discuss chemical and heavy metal pollution.
Describe agricultural run- off causing pollution
Explain bio- magnification
4. ORT 2 Com 4 WATER PURIFICATION
Explain importance of water purification

Discuss different methods of water purification
Describe thermal stratification
5. ORT 2 Com 5 HOUSING AND RADIATION
Enlist the criteria of health.

Discuss different standards of health .
Describe the modes of chemical destruction to health.
6. ORT 2 Com 6 NUCLEAR MEDICINE
Explain the origin and nature of radiation

Describe isotopes, half lifeand terrestrial radiation .
Enlist list man made radiation sources
707
7. ORT 2 Com7SPORTS MEDICINE
Explain the concept of sports medicine.

Describe the concept of fitness
Discuss the role of nutrition and exercise in physical fitness.
Enumerate the role of sports physician in the practice of sports medicine.
Discuss the use/abuse of drugs used in sports.
8. ORT 2 Com 8 CONTROL AND PREVENTION OF OCCUPATIONAL

DISEASES (Tutorial)
Control and prevention of occupational diseases

Describe silicosis, asbestosis.
Formers lungs byssinogis.
9. ORT 2 Com 9CONTROL AND PREVENTION OF OCCUPATIONAL

HAZARDS(Tutorial)
Enlist the prevention of occupational diseases
Describe the constructive mining
Control of occupational hazards
10. ORT 2 Com 10 DISPOSAL OF WASTE (Tutorial)
Explain different types of management regarding disposal of waste

Describe incineration
Discuss compositing of garbage
708
SCANERIO BASE LEARNING
1. ORT 2 Sbl 1 Bone Metabolic Disorders

Discuss the Osteomyelitis.
Highlight the investigations.
Describe the patho physiology.
Discuss the treatment.
2. ORT 2 Sbl 2 Osteoporosis

Enlist the investigations
Discuss the different causes of rickets/Osteomalacia
Enlist the sources of vitamin D and calcium and how Vitamin D gets activated
in the body into active form
Describe Pathophysiology of the condition
3. ORT 2 Sbl 3 Osteomalacia

Discuss the metabolic bone disease
Highlight the investigations you will like to do and give reasons for doing all
investigations
Discuss protocol for treatment of Osteomalacia
Understand the role of counseling for this case
4. ORT 2 Sbl 4 Fractures
5. ORT 2 Sbl 5 Bone Tumors

Classify the bone tumours
Highlight the basic Haematological investigation for bone tumors
Illustrate imaging studies
Discuss the management plan of different bone tumour
709
FIRST AID SKILLS PART 1 (BLEEDING, SOFT TISSUE INJURIES)
FIRST AID SKILLS PART 2 (BURNS, FRACTURES, VERTEBRAL INJURY)
This is one of the essential skills required to handle an injured victim or patient with acute
medical emergency before reaching the hospital in order to prevent disability and death.
LEARNING OBJECTIVES
After this session the student should be able to:
1. Assemble a First Aid Kit with at least twelve essential contents.
2. Demonstrate appropriate communication skills while handling a patient requiring first
aid.(especially reassurance to patient)
Following five common injuries will be addressed:-
I- Bleeding
3- Demonstrate the appropriate methods of managing external bleeding. (Direct pressure,
compressing pressure points, elevation).
II- Soft Tissue Injuries

4- Demonstrate proper management of wounds including assessment, cleaning and
dressing
(head, forearm and hand, leg and ankle).
III. Vertebral column Injury

5- Demonstrate correct rolls, moves, and lifts in transporting a patient to avoid spinal cord
injury (log roll, spine stabilization)
IV. Bony Injuries (Fractures)

6- Demonstrate the correct method of splinting fractures in the leg and arm.
V. Burns
7- Demonstrate the correct method of first aid management of burns.
710
ROUND
WEEKS/HOURS 1st 2nd 3rd 4 5 6 7 Total
OFF
ANATOMY 1 1 2 1.53
3
EMBRYOLOGY 2 2 1.53
BIOCHEMISTRY 1.5 1.5 1.5 1 5.5 4.23 4
RADIOLOGY 1 2.5 1.5 5 3.84 4
PHYSIO 1 1 0.76 1
12
PHARMA. 1.5 1 1.5 4 2.5 1.5 9.22 9
PATHO 2 1.5 3 2.5 1.5 4 2 16.5 12.69 13
PEADS 1 1.5 1 1 1.5 1 7 5.38 5

MEDICINE 1 2.5 3 3 3 12.51 9.62 10
ORTHO 4 3.5 1.5 1 1 3.5 14.5 11.15 11
78.01 59.95 60
SBL 3 3 3 3 3
20
COMM 1.5
1.5 3 2.5 3 3 1.5 16 15
.MEDICINE
ETHICS 5
TOTAL 12.5 19 16.0 19 16 17 9.5 109
711
ORTHOPAEDICS AND TRAUMA-2MODULE
(SEMESTER-VII)
THEORY

SEMESTER
ATP 25
EXAM
PAPER-II 80%
One best Questions
20
based on CBL
Total 100
MODULE EXAM
EMQs 10
ATP 20
MODULE PAPER 20%
One best Questions
20
based on SBL
Total 100
STRUCTURED VIVA

SUMMATIV
ASSESME
SEMESTE
R EXAM
See Semester
NT

E
Assessment Plan
ASSESSMENT TOOLS
Structured Feedback
Facilitator
NOTE: Paper I & IV-A of Semester-7 Examination are Based on EYE / ENT Module.
Paper III & IV-C of Semester-7 Examination are Based on Reproductive Syst.-2 Module.
712
CREDIT HOURS
SEMESTER-VII
ORTHOPAEDICS AND TRAUMA MODULE
Paper-II 4
ORTHOPAEDICS
AND TRAUMA
Paper-IV-B 2
713
Reproduction Module 2
Code: REP 2
Semester VII
Fourth Year MBBS
714
Spiral Sem. Modules

II

4 Week
wks
Second th
Spiral th
Trauma, 6 week
3 week 8 Weeks
/ Burns 2 wk
Weeks
th
th
PARALLEL THEMES:
715
Module Committee
Dr. Talat Mirza Professor of Pathology, DUHS
Dr. Rukhsana Rubeen Associate Professor of BiochemistryDUHS
Dr. Shamaila Khalid Assistant Professor of Pharmacology, DUHS
Dr. Jahan Ara Associate Professor of Gynae,& Obs. DUHS
Dr. Riffat Jaleel Associate Professor of Gynae&Obs.DUHS
Dr. Shaheen Bhatti Associate Professor of Medicine, DUHS
Dr. Fehmina Arif Professor of Pediatrics DUHS
Module Documented by:

DR. Arisha Sohail
Coordinated by:
DR. Arisha Sohail
Reviewed by:
Modular committee
716
RATIONALE:
A Student stepping into a medical school requires orientation, introduction to medical sciences
with respect to health & disease. A student also needs certain guidelines to achieve goals to
become a successful but ethical doctor in future.
More than half of the population of Pakistan are females. Diseases related to female and male
reproductive systems constitute a large segment of medical practice in all countries. These
diseases together with pregnancy and its related disorders are the core teaching in this module.
The importance of gynecology and obstetrics is well reflected in the curriculum as it will be
revisited as a subject in the third spiral.
The basic knowledge of anatomy, physiology, biochemistry, pharmacology and pathology has
already been imparted in the first Reproduction module. Inthis second, clinical, spiral the
student will develop further understanding of the pathology, clinical presentation, diagnosis
and management of reproductive disorders, normal pregnancy and its disorders.
TERMINAL OBJECTIVE:
At the end of this module students should be able to:
Recall the anatomy & physiology of male and female reproductive system.
Discuss the etiology of early pregnancy disorders.
Differentiate the non-neoplastic lesions of male and female genital tract.
Differentiate between primary and secondary amenorrhea and discuss the
management of infertility.
Interpret the semen analysis report.
Explain the clinical features diagnosis and management testicular tumors.
Define safe motherhood and its components.
Differentiate between the urinary and fecal incontinence its clinical presentation and
discuss the management plan.
Recognize the gestational diabetes mellitus and pregnancy induced hypertension and
their management.
Compare between antepartum and postpartum hemorrhage.
Enlist the principles of vaccinations and describe the E.P.I
Recognize the malposition and malpresentation of human fetuses and their
management
Illustrate the minor and major surgical gynecological and obstetrics procedures
Assess the respiratory distress n newborn and steps of neonatal resuscitation
Compare between normal and abnormal labor
717
LEARNING OBJECTIVES OF MODULE

Modes of information transfer, duration of teaching of each content and the
mode of assessment.
Lectures
Demo:
Tutorials
Practical
Skills Lab
CBL 6
teaching
Bed side
Study
Self
EMQS
One Best,
ATP
viva
Learning
Faculty Topic/ Content
Objectives
Rep 2 Ang1 Revisit of Female

GROSS genital system
1 * - *
Revisit of ANATOMY Rep 2 Ang2 Revisit of male genital
Anatomy system 1 * - *
Rep 2 Ang3 Review of pelvic
sructures&Pelvimetry 1 * * *
Rep 2 Phy1 Physiology of
Female/male hormones
1 * - *
Revisit of PHYSIOLOGY Rep 2 Phy2 Revisit of Menstrual
Physiology Cycle
1 * - *
To identify Rep 2 Pth1 FGT: Developmental
developmental anomalies abnormal and normal
disorders of PATHOLOGY sex, ambiguous genitalia, turners,
klinfelters 1 * * *
MGT and FGT
MGT: Cryptorchidsm, Epispadias,
Hypospadias, Hydrocoele,
Undescended testis
Discuss Rep 2 Pth2 Etiology of early

etiology PATHOLOGY pregnancy disorders
1 * - *
diagnosis and GYNECOLOGY Rep 2 Obg 1 Abortions
& OBSTETRICS \miscarriage
1 * - *
management
of early INTEGRATED Rep 2 Obg SBL 1
LEARNING
1 * - *
pregnancy
disorders GYNECOLOGY Rep 2Obg 2 Ectopic pregnancy
& OBSTETRICS
1 * - *
INTEGRATED Rep 2ObgSBL 2
LEARNING
1 * - *
GYNECOLOGY Rep 2 Obg3 Gestational
1
& OBSTETRICS trophoblastic diseases 1 * - *
718
Describe causes of MICROBOILOG Rep 2 Mic1Infectioninflammations
vaginal discharge
Y stis: lower gt vaginal discharge,
and genital ulcers
bartholinscyst/disease, genital
Describe STI of ulcers,HPV,HSV, HIV, other
female genital tract viruses.
with pertinent lab
investigations 1 * - *
Identify and discuss
causes clinical
presentation,
diagnosis and
management of
infections of vulva,
vagina
Discuss the GYNECOLOGY Rep 2 Obg 4Upper GTPID acute
causes & OBSTETRICS & chronic (cervicitis, endometritis,
1
pathogenesis, salpingitis, pelvic p)pelvic * - *
diagnosis tuberculosis
,complications
and management
Describe STI of GENERAL Rep 2 Sur 1 Infections of MGT
of PIDgenital
male SURGERY including epididimytis, orchitis,
tract with prostatitis. 1 * - *
pertinent lab
investigations
Discuss PATHOLOGY Rep 2 Pth 3
reproductive Endometerial Hyperplasia 1 1 * - *
hormones and
PHARMACOLO Rep 2 Pha1Synthetic male and female
pathophysiology,
diagnosis and GY sex hormones
management of
endometrial
1 * - *
hyperplasia
Identify
contraceptive Rep 2 Pha2Contraceptive
agents Preparations
1 * - *
including Rep 2 Obg 5Contraception (Fertility
various GYNECOLOGY Control)
methods their & OBSTETRICS
advantages and
disadvantages
1 * * *
contraindicatio
ns and failure
rate
Describe normal Rep 2 Peds 1Puberty &Disorders Of
puberty etiology PAEDIATRICS Puberty Precocious,
DelayedProblemsOfAdolescence And
management of
Pediatrics
1 * - *
precocious and
delayed puberty
Discuss, GYNECOLOGY& Rep 2 Obg6Pcos
diagnosis OBSTETRICS
1 * * *
consequences
INTEGRATED Rep 2 Gynae SBL 3
and management
of PCOS LEARNING 1 * - *
719
Describe etiology GYNECOLOGY& Rep 2 Obg 7Hirsutism/Virilisation
pathophysiology OBSTETRICS
diagnosis and
management of
1 * * *
hirstuism and
virulisation
Discuss etiology GYNECOLOGY& Rep 2 Obg
pathophysiology OBSTETRICS 8PathophysiologyMenstrualCycleAUB, 1 * - *
diagnosis and DUB
management of INTEGRATED Rep 2 ObgSBL 4
menstrual LEARNING
1 * - *
disorders
GYNECOLOGY& Rep 2 Obg 9Dysmenorrhea, PMS
OBSTETRICS
1 * * *
Rep 2 Obg 10Amenorrhoea, Primary
1 * * *
Rep 2 Obg 11SecondaryAmenorrhoea, 1 * * *
Describe GYNECOLOGY& Rep 2 Obg 12Menopause & HRT
mechanism OBSTETRICS
pathophysiology,
Diagnosisand
1 * * *
management of
menopause
Relate male GYNECOLOGY Rep 2 Obg 13Male And Female
and female & OBSTETRICS Infertility (Medical And Surgical 1 * - *
infertility with Causes)
pathological INTEGRATED
causes and LEARNING Rep 2 Obg SBL 5 1 * - *
mechanism GYNECOLOGY Rep 2 Obg 14AssistedReproductive
along with & OBSTETRICS Techniques
labortaryinvesti
gationsdiagnosi
s medical * - *
treatment and
surgical
procedures
Discuss PATHOLOGY Rep 2 Pth 4 Pre-InvasiveLesion Of
etiopathogenes FGT:VIN, VAIN,CIN, 1 1 * * *
is, diagnosis SKILL LAB Rep 2UGLSKILL:CATHETERIZATION
and
1 * * *
management GYNECOLOGY& Rep 2 Obg 15Diagnosis And
of preneoplasia OBSTETRICS Management Of Pre-Invasive Lesions 1 * - *
and neolplastic Of Vagina & Cervix
lesion of lower PATHOLOGY Rep 2 Pth5Non Neoplasic& Neoplastic
genital tract in Lesions Of Lower FGT 1
females and
* * *
males
Discuss the GYNECOLOGY& Rep 2 Obg 16Management Of Ca
benign and OBSTETRICS Cervix: 1 * - *
malignant Rep 2 Obg 17Benign And Malignant
tumors of Tumors Of Vulva
vulva, vagina
1 * - *
and cervices
720
Discuss GYNECOLOGY& Rep 2 Obg 18ClinicalDiagnosis
etiopathogenes OBSTETRICS &Management.Fibroids,EndometrialP
is, diagnosis olyps,EndometrialH/P: Pathology
1 * * *
&ClinicalAdenomyosis&Endometriosis
and
management, INTEGRATED Rep 2 ObgSbl 6
spread LEARNING
1 * - *
complications, PATHOLOGY Rep 2 Pth6Benign & Malignant 1
staging and Endometrial Tumors
1 * * *
prognosis of Rep 2 Obg 19Benign Tumors of Body 1
malignant GYNECOLOGY& Of Uterus * - *
tumors of OBSTETRICS Rep 2 Gynae
upper female 1
20MalignantTumoursofBody Of * - *
and male Uterus
genital tract PATHOLOGY Rep 2 Pth7Ovary:
NonNeoplasticLesions:Follicular,Corpu
sLuteumCysts,
ThecaLutealCysts,SurfaceEpithelialIncl
1 * * *
usion Cysts(Functional
Cysts)
Rep 2 Pth8Tumours
ofOvaryAndFallopian Tube
1 * * *
Rep 2 Pth 9Tumours Of
Ovary 1 1 * * *
GYNECOLOGY& Rep 2 Obg 21Clinical
1
OBSTETRICS MalignantTumoursOfOvaryAndFallopi * - *
an Tube
WHO strategies COMMUNITY Rep 2 Comm1Maternal Care
for safe MEDICINE
motherhood
initiative
1
-briefly describe * - *
the strategies
and discuss
their
importance of
reducing Rep 2 Pth10Neoplastic Leisions Of
Discuss PATHOLOGY
maternal
etiopathogenes Male Genital Tract (Testicular Tumors)
1 1 * * *
mortality in Rep 2 Sur2 Tumours Of Testis:
is, diagnosis GENERAL
Pakistan
and SURGERY (Management)
management,
spread
complications, 1
staging and * - *
prognosis of
malignant
tumors of male
genital tract
Describe GYNECOLOGY& Rep 2 Obg 22UrogynacologyUrinary
etiopathology OBSTETRICS AndFaecalIncontinence
1 * - *
diagnosis Rep 2 Obg 23Pelvic OrganProlapse
management
and
complications 1 * - *
of
urogynaecologi
calconditions
721
Discuss and PATHOLOGY rep 2 Pth11Mastitis, DuctEctasia,
analyze mass in FatNecrosis,
the breast in NonProliferativeAndProliferative
1 * * *
Breast Diseases
relation to
inflammatory, Rep 2 Pth12Risk Factors And
Classification Of Breast Tumors With 1
hyperplastic
Grading,Staging,Prognosis Lymphatic
1 * * *
and neoplastic
Drainage
disorders of
GENERAL Rep 2 Sur3 Diseases Of Breast 1
male and
female breast SURGERY Diagnosis And Management * - *
INTEGRATED Rep 2 Sur Sbl 6
LEARNING
1 * - *
Obstetrics Faculty Topic / Content
Tutorials
Practical
Lectures
Demo:
Study
Skills
CBL /
(REGULAR)
One
viva
Self
ATP
Best,
EMQ
SBL
Lab
S
Enlist PEDIATRIC Rep 2 Peds Sur 1Congenital
congenital SURGERY Anomalies ofFetus AndNewborn
abnormalities Structural /Chromosomal
Cryptorchism,Epispadias,Hypospadia
and their
s,Hydrocoele,UndescendedTestisHyd
*
causes with 1
-
rocephalusCleft Lip AndPalate,
relevant history CysticHygroma,HerniasCdh,Tev,Hem
taking and angioma,
methods of Goiter,Ambiguous
examination Genitalia
with diagnoses GYNAECOLOGY Rep 2 Obg 24 Prenatal 1
*
-
and & OBSTETRICS diagnoses:Noninvasiveand Invasive
management
Social obstetric COMMUNITY Rep 2 Comm 2Infant Care
options
care MEDICINE 1
-definition
*
-
-concept and
practice Rep 2 Obg25High risk pregnancy
Identify GYNAECOLOGY
pregnancies at & PlanManagementof high
risk OBSTETRICS riskpregnancyDiscuss
Plan clinicalRiskmanagement
management
*
*
-
of high risk 1
pregnancy
Discuss clinical
risk
management
Describe GYNAECOLOGY Rep 2 Obg26Normal fetalgrowth
normal and & anddevelopmentAbnormalitiesof
*
1
-
abnormal fetal OBSTETRICS fetalgrowth: IUGR,IUD

growth and
development
Growth COMMUNITY Rep 2 Comm 3Growth Monitoring
monitoring MEDICINE
-definition
*
*
-
uses 1
-
interpretation
722
Discuss clinical PEDIATRICS Rep 2 Peds 2 Clinical Presentation
presentation, Complication and out line of
causes, Management of IUGR baby
*
diagnosis and
-
1
management
of abnormal
fetal growth
Describe GYNAECOLOGY Rep 2 Obg27Amniotic fluid and
physiology of & abnormalities (poly hydramnios,
amniotic fluid OBSTETRICS oligohydramnios)
Discuss causes,
pathogenesis,
*
1
-
diagnosis and
management
of amniotic
fluid
abnormalities
Describe the GYNAECOLOGY Rep 2 Obg28Pretermlabour and
clinical & PPROM
presentation , OBSTETRICS
assessment,
1
*
*
*
complications
and
management
of preterm
birth
Discuss the effect PEDIATRICS Rep 2 Peds 3Causes of
of prematurity prematurity, PhysicalExamination
and PROM on
of a preterm,common problems
the Neonate
like Respiratory distress
hypothermia,Hypoglycemiahypoc 1
*
-
alcemia Infection
andFeedingproblems
Prevention of complications
Outline of management
INTEGRATED Rep 2 PedsSBL 6
1
*
*
-
LEARNING
Describe patho- PATHOLOGY Rep 2 Pth13Disorders of
physiology and placentation
*
*
*
disorders of
placentation
723
Describe patho- PATHOLOGY Rep 2 Pth14Describe the effect of
physiology of blood group Incompatibilities on
Rh the neonate
isoimmunizatio
n
Discuss
prevention and
management 1
*
*
*
1
of Rhesus
disease
Describe the
effect of blood
group
Incompatibilitie
s on the
neonate
Discuss causes PEDIATRICS Rep 2 Peds 4Antenatal screening,
,presentation screening inlabor room, Clinical
and presentation Investigations,
*
1
-
management complication management
of neonatal
jaundice
Identify clinical CLINICAL Rep 2 Med1 Medical disorders
presentation, MEDICINE ofpregnancy:Cardiac Diseases
*
1
-
patho- hemodynamic changes
physiology, GYNAECOLOGY Rep 2 Obg29Medicaldisorders of
diagnosis,
*
& pregnancy:Hypertensive Disorder 1
-
complications OBSTETRICS
and
GYNAECOLOGY Rep 2 Obg30Medicaldisorders
management
*
& ofpregnancy:Diabetes in 1
-
of medical
OBSTETRICS Pregnancy
disorders in
GYNAECOLOGY Rep 2 Obg31Medicaldisorders
pregnancy
& ofpregnancy:Hemotological
*
1
-
OBSTETRICS disorders in pregnancy
Discuss the PEDIATRICS Rep 2 Peds 5 Effects

effects of ofMedicaldisorders:Infant of
1
*
*
medical Diabetic mother -
disorders on
the neonates
Discuss clinical GYNAECOLOGY Rep 2 Obg32Ante partum
presentation, & Haemorrhage:Placenta
pathophysiolog OBSTETRICS Praevia , Abruptioplacentae
y, diagnosis, Vasa praeviaand localcauses
*
1
-
complications
and
management
of APH
Discuss clinical GYNAECOLOGY Rep 2 Obg33Post partum
presentation, & Haemorrhage: Uterine
pathophysiolog OBSTETRICS AtonyRetainedplacenta
y, diagnosis, Trauma Coagulationdisorders
*
1
-
complications andenlist
and surgicalInterventionsFormanagem
management ent
of PPH
724
Discuss clinical GYNAECOLOGY Rep 2 Obg34 Multiple pregnancy
presentation, &
patho OBSTETRICS
physiology,
diagnosis,
*
complications 1
-
and
management
of multiple
pregnancy and
labor
Discuss GYNAECOLOGY Rep 2 Obg 35Abnormal labor:
etiology, & Abnormalities of pelvis,
clinical OBSTETRICS Contracted pelvis Poor progress in
features,
labour
*
*
*
complications 1
and Prolonged /Obstructed
management Labour Augmentation of labour
of abnormal
labour
Immunization COMMUNITY Rep 2 Comm 4 Principles of
-Immunity, MEDICINE vaccination
*
types of 1
-
immunity, EPI
schedule
IMNCI COMMUNITY Rep 2 Comm Med 5Introduction
- introduction MEDICINE to IMNCI
-enlist
1
components-
*
-
strategies and
importance of
IMNCI
IMNCI COMMUNITY Rep 2 Comm Med 6 1
*
*
-
MEDICINE CoughDiarrhea
Fever
Discuss causes, PEDIATRICS Rep 2 Peds 6Neonatal sepsis
clinical Clinical presentation,
presentations, septic screening of the neonate
complications 1
and outline of management
*
*
-
and
management
of neonatal
sepsis
Describe GYNAECOLOGY Rep 2 Obg 36Malpresentations
indications and & andmalpositionsExternal 1
*
*
*
1
complications OBSTETRICS Cephalicversion
of operative
delivery Rep 2 Obg 37breech vaginal
*
*
*
delivery 1
Rep 2 Obg38Minor & Major

*
*
*
Surgical Procedures 1
Rep 2 Obg39Instrumental
*
*
*
VaginaldeliveryOperative 1
Interventionsincluding LSCS
725
Discuss the PEDIATRICS Rep 2 Peds 7Causes of birth
causes, asphyxia, clinical presentation,
presentation and evaluation and outline of
management of
*
*
*
management 1
birth asphyxia
Identify common birth injuries in
and birth injuries
the neonates, their complications
and outline the management.
To enlist and PEDIATRICS Rep 2 Peds 8Indications of
perform the Resuscitation Prerequisites
steps of Steps of resuscitation
*
*
*
1
neonatal Routine care,PositivePressure
Resuscitation ventilation Chest compression,
Use of drugs
Describe the PEDIATRICS Rep 2 Peds 9Congenital and
causes clinical acquiredpneumonia, Hyaline
presentation membrane disease, Meconium
and outline of aspiration, Transienttachypnoea,
*
1
-
management Pneumothorax
of respiratory Congenitalheartdiseases
distress in
newborn
Discuss causes, GYNAECOLOGY Rep 2 Obg40Obstetric
clinical & emergencies:Severe PE /
presentation, OBSTETRICS EclampsiaHaemorrhage
diagnosis and VenousThromboembism
management Amniotic fluidembolism
*
1
-
of obstetric Post-partumcollapse
emergencies Inversion
ofuterusUterineRuptureUmbilicalc
ordprolapseShoulderdystocia
Manage normal GYNAECOLOGY Rep 2 Obg 41Puerperium:
puerperium & NormalAbnormal:SecPPHHaemato
Diagnose and OBSTETRICS maObstetricpalsySymphysispubisd
*
1
-
manage iastasisPuerperialpyrexia and
problems of sepsis
puerperium
Describe the PEDIATRICS Rep 2 Peds 10Breast feeding in
steps of babies with special problems
*
*
*
1
positioning and (Preterm, cleft lip)
attachment of COMMUNITY Rep2 Comm 7 Breast feeding
Breast feeding MEDICINE
Discuss the
common and
*
1
-
special
problems of
breast feeding
Describe GYNAECOLOGY Rep 2 Obg 42Safemotherhood
concept and &
*
pillars of safe OBSTETRICS 1

-
motherhood,
MDGs
726
Describe GYNAECOLOGY Rep 2 Obg 43 Obstetric Statistics:
terminologies & MMR, PNMR causes of maternal
in relation to OBSTETRICS andperi-natalmortality and
obstetric Neonatalmortality rate
statistics
*
Describe causes 1
-
of maternal,
perinatal
mortality and
neonatal
mortality rate
727
REPRODUCTION MODULE II
TIME TABLE
FIRST WEEK
Days 8:30 to 9:30 9:30 to 10:30 11:00 12:30 1:30-3:00

A=Anatomy:Review of pelvic
structures &pelvimetryName of
Faculty Venue
B=PathologyPracticalHydatidif
ormmoleName of Faculty Venue
C1=Skill lab: Breast
Anatomy
Clinical Examination
Revisit of Female Physiology
Genital Tract Revisit of Menstrual Posting C2= Self study
1 Name of Faculty Cycle D1=Case Preparation
Name of Faculty
Venue
GynaeWARD ( I)
Venue D2=Case Preparation
GynaeWARD ( II)
D3=Case Preparation
GynaeWARD ( III)
E= Physiology: Physiology of
male & female hormonesName of
Faculty Venue
2 PUBLIC HOLIDAY
Pathology Clinical
Anatomy 1. C
Developmental Posting
Revisit of Male 2. D
disorders of MGT
3 Genital tract
and FGT Name of Faculty 3. E1,(E2= Self Study)
Name of Faculty
Venue
Name of Faculty Venue 4. A
Venue 5. B
Pathology 1.B
Etiology of early 2.C 10:30-12:00
Pregnancy 3.D1,
4 Disorders
(D2= Self Study) Clinical Posting
Name of Faculty
Venue 4.E
5.A
5
MODULE TEST THEORY AT OJHA CAMPUS
(02:00pm till 04:30pm) ( Orthopedic)
728
SEMESTER 7
REPRODUCTION MODULE II
TIME TABLE WEEK 02,
Days 8:30 to 9:30 9:30 to 10:30 11:00 12:30 1:30-3:00
Pathology Gynecology
Gestational 1.D
Etiology of early 2.E
Pregnancy trophoblastic
diseases 3.A1
1 Disorders Clinical
Name of Faculty (A2=Self Study)
Name of Faculty Posting
Venue Venue 4.B
5.C
Gynecology
Diagnosis & management 1.B 1.E
of early pregnancy 2.C
Clinical 2.A
disorders 3.D1,
2 Posting 3.B (B2=Self study)
(Abortions/Miscarriage) (D2=Self Study)
Name of Faculty 4.E 4.C
Venue 5.A 5.D
3 PUBLIC HOLIDAY
A= Case Preparation
B=Pathology Practical
Endometrial
Gynecology Pathology HyperplasiaName of Faculty
Pathophysiology of Venue
4 Ectopic pregnancy
Name of Faculty Endometrial Clinical C2= Skill lab: Breast
Venue Hyperplasia Posting Examination
Name of Faculty C1==Self Study
Venue D=Pharmacology
tutorial=Synthetic male &
female HormonesName of
Faculty Venue
E= CBL
MICROBIOLOGY GYNECOLOGY
STIs & PID in
STIs in females 10:30-12:00
5 female
Name of Faculty Clinical Posting
Venue
Name of Faculty
Venue
GENERAL
SURGERY 1. B
STIs in males: MGT RESEARCH 2. C
including METHODOLOGY Clinical
6 3. D2= SKILL LAB
Name of Faculty
Epididimytisorchitis, Posting D1= SELF STUDY
Venue
prostatitis 4. E
Name of Faculty
Venue 5. A
729
REPRODUCTIVE MODULE 2
TIME TABLE WEEK 03SEMESTER - 7
Days 8:30 to 9:30 9:30 to 10:30 11:00-12:30 1:30-3:00
Pharmacology 1. C
Contraceptive
Gynecology 2. D
Contraception Clinical 3. E2=Skill Lab
1 Preparations Posting (E1= Self Study)
4. A
5. B
1. D
Pediatrics 2. E
Gynecology
Puberty & disorders 3. A2= Skill Lab
PCOS Clinical
2 of puberty ( A1= Self Study)
Name of Faculty Venue Posting
Name of Faculty Venue 4. B
5. C
Pathology Gynecology 1. E
Infections and Pre- Pathophysiology of 2. A
invasive lesion of FGT: menstrual cycle Clinical 3. B2= Skill Lab
3
VIN, VAIN, CIN AUB, DUB Posting (B1= Self Study)
Name of Faculty Venue Name of Faculty Venue 4. C
5. D
Pathology
Non-neoplastic and Gynecology Gynecology
neoplastic lesions of Clinical Primary Amenorrhoea
4 Hirsutism
Lower Female genital Posting Name of Faculty Venue
tract FGT
/Virilisation
Gynecology
Gynecology SecondaryAmenorrh
5 Dysmenorrhea, PMS oea Clinical Posting
6 PUBLIC HOLIDAY
730
REPRODUCTIVE MODULE II
Days 8:30 to 9:30 9:30 to 10:30 11:00 12:30 1:30-3:00
A=SBL
B=Case Presentation WARDS

Gynecology Gynecology
Primary C= Pathology practical: Pre-invasive
Dysmenorrha, lesion of FGT: VIN, VAIN, CIN Name of
Amenorrhoea
1
PMS Name of Faculty Venue Clinical Posting Faculty Venue
Name of Faculty Venue D=Pathology tutorial: Lower Female
genital tract FGT tumors Name of Faculty
Venue
E1=Skill Lab: Catheterization E2= Self
Study
Gynecology Gynecology 1.B
Secondary Menopause & HRT 2.C
2 Amenorrhoea Name of Faculty Venue 3.D
Clinical Posting 4.E
5.A1=skill lab A2=Self study
Gynecology
Etiology & 1.C
Gynecology 2.D
investigation of
3 3.E
infertility Management of Clinical Posting 4.A
(Interpretation of infertility
5.B1= Skill Lab B2= Self Study
semen report)
Gynecology Gynecology 1.D
Diagnosis and Management of Ca 2.E
management of pre- cervix 3.A
4
Clinical Posting 4.b
invasive lesions of
5.C1= Skill Lab C2= Self Study
vagina & cervix
Pathology G surgery
Neoplastic disorders Testicular tumors
5 male genital tract management Clinical Posting
(Testicular Tumors) Name of Faculty Venue
Pathology Gynecology
1.E
Tumors of Uterine Benign & Malignant
2.A
corpus tumors of Vulva 3.B
6
(Benign and Malignant Clinical Posting 4.C
endometrial Tumors) Name of Faculty Venue 5.D1= Skill Lab D2= Self Study
731
REPRODUCTIVE MODULE II
Days 8:30 to 9:30 9:30 to 10:30 11:00 -12:30 1:30-3:00
A= Case Presentation: WARDS
B= Pathology Practical:
:Testicular Tumors
Gynecology & Gynecology &
Obstetrics Obstetrics
Benign Tumors of Malignant Tumors of Clinical
1 C= Pathology Tutorial: Tumors
Uterine corpus Uterine corpus Posting
of uterine Corpu Name of Faculty
Name of Faculty Venue Name of Faculty Venue Venue
D1= Self Study

D2= Skill lab = Catheterization
E= SBL: WARDS
Research 1. B
CM Methodology 2. C
Maternal Care Research Proposal & Clinical 3. D
2 Name of Faculty Venue Literature Review Posting 4. E1=SELF STUDY
E2= SKILL LAB
5. A
Gynecology 1. C
Clinical diagnosis & Pathology
2. D
Management of Ovary Non-neoplastic
lesions (Functional Clinical 3. E
3 FibroidsAdenomyosis
Posting
& endometriosis Cysts) 4. A1=SELF STUDY
Name of Faculty Venue Name of Faculty Venue A2= SKILL LAB
5. B
1. D
Pathology Gynecology &
Tumors of fallopian 2. E
Obstetrics
tube and Ovary Clinical 3. A
4 Ovarian tumors
Posting
Name of Faculty Venue Name of Faculty Venue 4. B1=SELF STUDY
B2= SKILL LAB
5. C
Pathology CM
Tumors of Ovary Infant Care Clinical
5 Name of Faculty Venue Name of Faculty Venue Posting
1. E
Gynecology Research
2. A
Urinary and Fecal Methodology
Clinical 3. B
6 incontinence Name of Faculty Venue
Posting 4. C1=SELF STUDY
C2= SKILL LAB
5. D
732
REPRODUCTION MODULE 2
TIME TABLE WEEK (06) SEMESTER 7
Day
8:30 to 9:30 9:30 to 10:30 11:00 -12:30 1:30-3:00
s
1. A=Case Preparation (Obstetrics)
Pathology WARDS
Mastitis, duct ectasia, 2.B=Pathology Practical: Tumors of
fat necrosis, non Gynecology the ovary Name of Faculty Venue
1 proliferative and Pelvic organ prolapse Clinical Posting
proliferative breast Name of Faculty Venue 3.C=Pathology Tutorial: Breast tumors
diseases
Name of Faculty Venue 4.D=SELF STUDY
5.E=SBL WARDS
Pathology
1. B
Risk factors ,
G. Surgery 2. C
classification of breast
Diseases of Breast
tumors with grading, 3. D
2 Diagnosis and Clinical Posting
staging, prognosis 4. E
management
with lymphatic
Name of Faculty Venue 5. A
drainage
Pediatrics Surgery 1. C
Obstetrics
Congenital 2. D
Prenatal diagnosis:
abnormalities with
3 non invasive and Clinical Posting 3. E
diagnoses and
Invasive 4. A
management options
Name of Faculty Venue 5. B
1. D
Obstetrics Obstetrics 2. E
4 High risk pregnancy IUGR, IUD Clinical Posting 3. A
4. B
5. C
Pediatrics
Clinical presentation , Community
complications and out Medicine
5 Clinical Posting
line of management of MCH indicators
IUGR baby Name of Faculty Venue
Research 1. E
Obstetrics methodology 2. D
Amniotic fluid Study Design & Clinical
6 3. A
abnormalities Research Ethics Posting
Name of Faculty Venue Name of Faculty Venue 4. B
5. C
733
REPRODUCTION MODULE 2
TIME TABLE WEEK 07SEMESTER 7
Days 8:30 to 9:30 9:30 to 10:30 11:00 12:30 1:30-3:00
Obstetrics Pathology
Pediatrics Pathophysiology of Rh
Preterm labour and Clinical Posting
1 Prematurity incompatibility
PPROM Name of Faculty Venue
Pathology
Disorders of Obstetrics
Pediatrics
placentation, Clinical Posting Hypertension in
2 Neonatal Jaundice
Name of Faculty Venue preeclampsia pregnancy
&eclampsia Name of Faculty Venue
Obstetrics
Obstetrics
Haematological CM
Diabetes in Clinical Posting
3 disorders in Principles of vaccination
pregnancy Name of Faculty Venue
pregnancy
Obstetrics
Pediatrics Ante partum
5 Infant of Diabetic mother Clinical Posting
Name of Faculty Venue Haemorrhage
Medicine
Obstetrics
Hemodynamic CM
Post partum Clinical Posting
6 changes and Immunization
Haemorrhage Name of Faculty Venue
cardiac disease in
pregnancy
734
REPRODUCTION Module 2
Days 8:30 to 9:30 9:30 to 10:30 11:00 12:30 1:30-3:00

1.A=Case Presentation Obstetrics
2.B=Pathology Tutorial :Rh
Obstetrics Obstetrics incompatibility Name of Faculty
1 Multiple Pregnancy Abnormal Clinical Posting Venue
Name of Faculty Venue Labour& CPD 3.C=CBL Surgery

Name of Faculty
Venue
4.D=CBL Peads
5.E=Self study
Peadiatrics Research 1. B
Infant of diabetic Methodology 2. C
2 mother Name of Faculty Clinical Posting 3. D= CBL SURGERY
Name of Faculty Venue Venue 4. E
5. A
1. C
Obstetrics 11:00 TO 12:00 12:00 TO 01:00
Peadiatrics Breech vaginal CM 2. D
3
Pediatrics IMNCI
Neonatal Sepsis delivery 3. E= CBL SURGERY
Birth asphyxia Name of
Name of Faculty Venue Name of Faculty 4. A
Name of Faculty Venue Faculty Venue
Venue
5. B
1. D
Obstetrics Obstetrics Research
Pediatrics Malpresentations 2. E
Minor and major methodology
4 Neonatal Resuscitation and malpositions 3. A= CBL SURGERY
surgical procedures Name of
Name of Faculty Venue Name of Faculty 4. B
Name of Faculty Venue Faculty Venue
Venue
5. C
Obstetrics
11:00 TO 12:00
Pediatrics Instrumental
Obstetrics
respiratory distress in vaginal Delivery
5 including LSCS Perpeurium
newborn
Name of Faculty Normal &Abnormal
Venue Name of Faculty Venue
Pediatrics Obstetrics
Problems Obstetrics Safe 1. E
Pediatrics associated with Obstetrical Motherhood,MDG 2. A
Breast feeding lactation in emergency s
6 3. B =CBL SURGERY
and lactation mothers Name of Faculty Name of Faculty
Name of Faculty Venue Name of Faculty Venue 4. C
Venue
Venue 5. D
735
Reproduction Module 2
Days 8:30 to 9:30 9:30 to 10:30 11:00 12:00 12:00 ---- 01:00 1:30-3:00
Obstetrics
Obstetrics Obstetrics CM
Obstetric
Peurperium Normal Safe Breast
&abnormal Statistics:
1 Motherhood, Feeding
MMR,PNMR
Name of Faculty
MDGs Name of Faculty Name of
Venue Name of Faculty Venue Faculty Venue
Venue
2 SELF STUDY
3 MODULE TEST
736
LEARNING OBJECTIVES
GROSS ANATOMY
1-REP 2 Ang1 Revisit of Female genital system
Describe female genital organs.

Identify supports of ovaries & uterus.
Discuss ovarian cycle & oogenesis.
2-REP 2 Ang2 Revisit of male genital system
Describemale genital organs.

Discussrole of testosterone hormone.
Enlist composition & functions of semen.
PHYSIOLOGY
1- REP 2 Phy1Physiology ofFemale/male hormones
Define menstrual cycle.

Describe the physiologic changes that occur in the female reproductive organs during
the menstrual cycle.
Explain the regulation of menstrual cycle.
Express the applied physiology
Pharmacology
1-REP 2 Pha1Contraceptive Preparations
Classify cotraceptive preparations.

Describe the methods of preparation of Contraceptives.
Describe mechanism of action of different contraceptives.
Enlist the indications and contraindications of contraceptives
737
PATHOLOGY
1-REP 2 Pth1Developmental disorders of MGT and FGT
Describe structure and function of male and female genital tract.

Discuss the mechanism of normal sexual determination and differentiation.
Identify abnormal sex chromosome complexes.
Discusssexual determination.
Discuss development of gonads.
Identify anomalies of female genital tract.
Identifyanomalies of male genital tract.
2-REP 2 Pth2Etiology of early Pregnancy Disorders
Define abortion.
Define molar pregnancy.
Describetypes of moles.
Defineectopic pregnancy.
3-REP 2 Pth 3Pathophysiology of Endometrial Hyperplasia
Define dysfunctional uterine bleeding.

Enlist the causes of DUB.
Define endometrial hyperplasia.
Describe the different morphological types of endometrial hyperplasia.
4-REP 2 Pth4Infections and Pre-invasive lesion of FGT: VIN, VAIN, CIN
Enlistnames the Lichen Disorders.

Enlistthe microscopic features of Lichensclerosus and Lichen simplex chronicus.
Explain VIN and CIN.
Describe the risk factors of the above mentioned factors.
5-REP 2 Pth5Non-neoplastic and neoplastic lesions of Lower Female genital tract FGT
Describe the non neoplastic conditions of the Endometrium, including acute &
chronic endometritis.
Define Adenomyosis and endometriosis.
Enlistthe microscopic features of adenomyosis and endometriosis.
Describe the salient features of endometrial polyps.
738
6-REP 2 Pth6Tumors of Uterine corpus (Benign and Malignant endometrial Tumors)
Describe the types of endometrial carcinomas.

Enlistthe conditions which are associated with the Endometrial carcinomas.
Enlistthe morphological appearances of the endometrial carcinoma.
Describe grades endometrial carcinomas.
Define malignant mixed mlleriantumors and adenosarcoma.
Differentiate between leiomyoma and leiomyosarcoma.
7-REP 2 Pth7Ovary Non-neoplastic lesions (Functional Cysts)
Define Ovarian Cysts.

Enlistthe different functional cysts of ovary.
Enumerate the microscopic features of functional cysts.
Describe the pathologic ovarian cysts.
Explain poly cystic ovarian syndromes.

8- REP 2 Pth8Tumors of fallopian tube and Ovary
Explain Paratubal cysts, acute and chronic cervicitis.

Describe classification of the ovarian tumors.
Describe the WHO classification of ovarian tumors.
Enlist the surface epithelial tumors of ovary.
Describethe morphology and salient features of different surface epithelial tumors.
9 -REP 2 Pth9Tumors of Ovary
Enlistthe different types of germ cell tumors.

Describe the gross & microscopic features of germ cell tumors.
Explain the different types of sex cord stromal tumors.
Describe the salient features of granulosa cell tumor and sertoli cell tumors.
10-REP 2 Pth10Neoplastic disorders male genital tract (Testicular Tumors)
Describeclassification of testicular tumors.

Describemorphology of different testicular tumors.
Discuss clinical features of germ cell testicular tumors.
Discussclinical staging of testicular tumours.
Enumerate differenttumour markers.
11-REP 2 Pth11Mastitis, duct ectasia, fat necrosis, non proliferative and proliferative
breast diseases
Defineacute mastitis.
Defineperiductal mastitis.
Definemammary duct ectasia.
739
Definefat necrosis.
Enlistnon proliferative breast diseases.
Enlistproliferative breast diseases without atypia.
12-REP 2 Pth12Risk factors , classification of breast tumors with grading, staging,

prognosis with lymphatic drainage
Describenormal anatomy of breast.

Describelymphatic drainage of breast.
Describeclassification of breast tumors.
Discussgrading and staging of breast tumors.
13-REP 2 Pth13Disorders of placentation, preeclampsia &eclampsia
Define twin placentas

Describeabnormalities of placental implantation.
Enlistplacental infections.
Definepreeclampsia.
Defineeclampsia.
14-REP 2 Pth14Pathophysiology of Rh incompatibility
Enumerate 5 major Rh antigens.

Describecharacteristics of HDN.
Establish the diagnosis of HDN.
Differentiate between ABO and Rh HDN.
Enlist the tests used for detection of fetomaternal hemorrhage.
Identify the blood group to be used in HDN.
MICROBIOLOGY
1- REP 2 Mic 1STIs in females
Enlist medically important sexually transmitted infections.

Describe pathogenesis and histopathological changes due to such infections
Enlist relevant lab.diagnostic tests
COMMUNITY MEDICINE
1- REP 2 Comm1Maternal Care
Define Reproductive health
Identify the components of Reproductive health
Enlist the aims and objectives of Reproductive health
Define and discuss the maternal Health
Discuss the importance of antenatal visits
740
2- REP 2 Comm 2Infant Care
Define infant care

Identify the components of infant care
Discuss parameters for normal growth and development.
List uses of growth chart.
Discuss the importance of breast feeding in infants.
3-REP 2 Comm 3 Growth Monitoring
List Indicators of MCH Care

Define and discuss the causes of maternal Mortality.
Define and discuss the causes of neonatal/Infant Mortality.
Discuss importance of reducing maternal mortality in Pakistan
Describe the strategies of reducing maternal mortality in Pakistan.
4-REP 2 Comm 4Principles of vaccination
DescribeAdaptive immune system.

DefineSpecificity and memory.
Describevaccine classification.
Describe the classification of vaccine types.
DefineSeropositivity
DefineSeroconversion
DefineSeroprotection
DefineImmunogenicity
5-REP 2 Comm Med 5Introduction of IMNCI.
Define IMNCI.
Enlist components of IMNCI.
Discuss strategies and importance of IMNCI.
6 REP2Comm Med 6Cough , Diarrhea, Fever
Discuss general knowledge of communicable diseases .

Describe elements of prehospital protective equipment (PPE)
Explain concepts of protection in the field (decontamination and PPE).
Discuscritical emerging and concerning communicable
diseases most relevant to prehospital care
7-REP2 Comm 7Breast Feeding.
Describe anatomy and physiology of breast.

Discuss importance of breast feeding.
Enlist diff. types of breast milk.
Describe composition of breast milk.
Enlist contraindications of breast feeding.
741
Discuss strategy of WHO breast feeding
GYNAECOLOGY & OBSTETRICS
1- REP 2 Obg 1Diagnosis & management of early pregnancy disorders

(Abortions/Miscarriage)
Define miscarriage & abortion with prevalence

Describe etiology& pathogenesis
Differentiate between various types of miscarriage with clinical & ultrasound diagnosis
Discuss management of each type
2- REP 2Obg 2Ectopic pregnancy
Define and classify the sites of ectopic pregnancy

Describe the etiology of ectopic pregnancy
Discuss the clinical presentation of ectopic pregnancy
Enlist the investigations for ectopic pregnancy
Discuss the medical and surgical management of ectopic pregnancy
3- REP 2 Obg3Gestational trophoblastic diseases
Define different types of trophoblastic Tumors

Describe the pathology of trophoblastic Tumors
Discuss the diagnosis, management and treatment of trophoblastic tumors
4-REP 2 Obg 4STIs & PID in female
Enumerate the causes of PID

Discuss the clinical features of PID
Enlist the investigations for PID
Discuss the management ,treatment and follow up of PID
5- REP 2 Obg 5Contraception
List different methods of contraception.

Describe the mechanism of action of different contraceptive methods.
Identify the indications and contraindications of different contraceptives
Discuss the side effects of different contraceptive preparations
742
6-REP 2 Obg6PCOS
Explain the Etiology of PCOs

Describe the Pathophysiology of PCOs
Establish the Diagnosis of PCOs
Discuss Consequences and management of PCOs.
7-REP2 Obg 7Hirsutism/Virilisation
Define Hirsuitism
Enumerate the causes of hirsuitism
Enlist the investigations for hirsuitism
Discuss the management and treatment of hirsuitism.
8-REP 2 Obg8Pathophysiology of menstrual cycle AUB, DUB
Recall physiology of menstruation

Describe terminologies & causes of AUB
Discuss patho-physiology of DUB, esp role of eicosanoids
Discuss types, causes, diagnosis of DUB
Enumerate investigations with relevance
Discusmedical & surgical management options
9-REP 2Obg 9Dysmenorrhea, PMS
Define and classify dysmennorhea.

Describe pathophysiology of dysmennorhea.
Enlist the investigations for dysmenorhea.
Discuss the management and treatment of dysmennorhea.
Define and classify pre menstrual syndrome.
Describe etiology of pre menstrual syndrome.
Establish the diagnosis of pre menstrual syndrome.
Discuss management and treatment of pre menstrual syndrome.
10-REP2 Obg 10Primary Amenorrhoea
Define primary amennorhea

Enumerate clinical causes of primary amennorhea
Discuss the various causes of disorders of primary amennorhea
Enlist the investigations for primary amennorhea
Discuss the management and treatment of primary amennorhea
743
11-REP 2 Obg 11Secondary Amenorrhoea
Define secondary amennorhea

Enumerate clinical causes of secondary amennorhea
Discuss the various causes of disorders of secondary amennorhea
Enlist the investigations for secondary amennorhea
Discuss the management and treatment of secondary amennorhea
12-REP 2 Obg 12Menopause& HRT
Define Menopause
List causes of menopause
Explain Pathophysiology of menopause
Discuss Mechanism of menopause
Discuss Diagnosis ,management and tretment of menopause
13-REP2 Obg 13Etiology& investigation of infertility (Interpretation of semen report)
Describe the etiology of female infertility.

Enlist the investigations for male & female infertility.
Interpret the semen report.
Enumerate the clinical causes of male and female infertility.
14-REP 2 Obg 14Management of infertility
Define Assisted reproduction.

Enlist the available methods for assisted reproduction.
Discuss the indications for assisted reproduction.
Describe the complications of assisted reproduction.
15-REP2 Obg 15Diagnosis and management of pre- invasive lesions of vagina & cervix
Identify the risk factors for cervical cancer.

Enumerate clinical causes of cervical cancer.
Enlist the investigations for cervical cancer.
Discuss management and treatment of cervical cancer
16-REP 2Obg 16Management of Ca cervix
Describe the histopathology of cervical carcinoma.

Enumerate the clinical causes of cervical carcinoma.
Enlist the investigations for cervical carcinoma.
Describe classification of cervical carcinoma on basis of staging.
Discuss management and treatment of cervical carcinoma.
744
17-REP 2 Obg 17Benign & Malignant tumors of Vulva
Explain the anatomy of vulva.

Discuss clinical assessment; history & examination
Identify the normal Variants
Describe the pathology of Benign Tumors&Vulval intraepithelial neoplasia.
Discuss the treatment of vulval carcinoma.
18-REP 2 Obg 18Clinical diagnosis & Management of Fibroids Adenomyosis& endometriosis
Define fibroids, polyps, endometrial atypia.

Explain etiology of fibroids polyps, endometrial atypia.
Describe classification of fibroids.
Discuss clinical presentation ,diognosis, management and treatment of fibroids and
polyps.
19-Rep 2 Obg 19Benign Tumors of Uterine corpus

Define fibroids.
Describe classification of different types of fibroids.
Describe the pathogenesis of fibroids.
Enlist the investigations for fibroids.
Discuss e management and treatment of fibroids.
20-REP 2Obg 20Malignant Tumors of Uterine corpus
Describe the etiology of endometrial cancer.

Identify the risk factors for endometrial cancer.
Describe classification on the basis of staging.
Enlist the investigations for endometrial cancer.
Discuss the treatment of endometrial cancer.
21-REP 2 Obg 21Ovarian tumors
Define Ovariantumours.
List symtomps of ovarian tumours.
Describe different types of ovarian tumours
Discuss diagnosis , management and treatment of ovarian tumours.
22-REP 2 Obg 22Urinary and Fecal incontinence
Define urinary and fecal incontinence.

Describe the sites of urine leakage.
Enlist causes of urinary fistula.
Describe types of obstetrical fistulae.
Discuss diagnosis, management and treatment of obstetrical fistulae.
745
23REP2 Obg 23Pelvic organ prolapse
Define UVP
Describe prevalence, classsification, grading of UVP
Describe aetiopathogenesis in relation to pelvic floor supports.
Describe symptoms associated with uvp, diagnosis & differential diagnosis.
Enumerate complications of prolapse,
Discuss relevant investigations.
Describe preventive measures.
Describe conservative management.
Enlistsurgical procedures.
24-REP 2 Obg 24Prenatal diagnoses: non invasive and Invasive
Describe aims of antenatal screening.

Discuss principles of antenatal screening.
The diagnostic tests.
Describe the procedures of various screening tests.
Enlist U/S markers of various congenital anomalies.
25-REP 2 Obg25High risk pregnancy
Define high risk pregnancy.

Enlist risk factors of high risk pregnancy.
Discuss the management of high risk pregnancy.
Discuss the clinical risk assesssment and mode of delivery.
26-REP 2 Obg26IUGR, IUD
Define IUGR.
Describe risk factors for IUGR.
Discuss classification of IUGR.
Explain etiology of IUGR.
Explain the causes of IUGR.
Discuss diagnosis and management of IUGR baby.
27-REP 2 Obg27Amniotic fluid and abnormalities
Define physiology of amniotic fluid.

Describe the asesssment of amniotic fluid.
Describe types of amniotic fluid abnormalities.
Enlist causes of hydromnias.
Discuss diagnosis , management and treatment of hydromias.
746
28- REP 2 Obg28Preterm labour and PPROM
Define Preterm labor

Explain etiology of preterm labour.
Describe screening for preterm labor
Discuss diagnosis of preterm labour
DrescribeTocolysis and Tocolytic agents
Enlist uses of Tocolytics.
Discuss Delivery of a preterm baby
29 -REP 2 Obg29Hypertension in pregnancy

Describe hypertension in pregnancy.
Explain pathological causes of PIH.
Describe types of PIH.
Enlistthe risk factors for PIH.
Discuss diagnosis , management and treatment of PIH.
30 -REP 2 Obg30Diabetes in pregnancy
Describe physiological changes of glucose metabolism in pregnancy.

Explain classification of diabetes.
Enlistthe risk factors for gestational diabetes.
Discuss the diagnosis ,management and treatment of gestational diabetes.
Describe the effects of GDM on neonates.
31-REP 2 Obg31Haematological disorders in pregnancy
Define platelet disorders.

Describe types of platelet disorders in pregnancy.
Enlist investigations for platelet disorders in pregnancy.
Discuss management of delivery in platelet disorders of pregnancy.
32-REP 2 Obg32Ante partum Haemorrhage
Define antepartum hemorrhage.

Enlist causes of antepartum hemorrhage.
Explain the classification.
Discuss assessment and management of antepartum hemorrhage
33-Rep2 Obg33Post partumHaemorrhage
Define PPH.
Enlist major causes of PPH.
Discuss factors leading to PPH.
Interpret the lab investigations.
Discuss diagnosis, management and treatment of PPH.
747
34-REP 2 Obg34 Multiple Pregnancy
Define multiple pregnancy.

Enlistthe maternal risk factors of multiple pregnancy.
Discuss the nutrition for multiple pregnancy.
Explain Twin-Twin transfusion syndrome.
Discuss the clinical management and procedures for multiple pregnancy.
35-REP 2 Obg35 Abnormal Labour& CPD
Define abnormal labour.

Assess progress of labour.
Explain cervicogram.
Describe types of abnormal labour.
Discuss the determinants of labour.
Discuss diagnosis and management of abnormal labour.
36-Rep 2 Obg 36 Malpresentations and malpositions
Define fetal malposition and malpresentation.

Explain different types of malposition.
Discuss management of different types of malposition
37-REP 2 Obg37 Breech vaginal delivery
DefineBreech vaginal delivery.

Describe Types of Breechvaginal delivery.
EnlistComplications of Breech delivery.
DiscussManagementof Breech delivery.
DefineTerm breech.
Discuss management of Caesarean for Breech delivery.
DefineExternal cephalic version
38-REP 2 Obg 38Minor and major surgical procedures
Describe gynaecological procedures of ovary, vagina, vulva, fallopian tubes.

Explain hysterectomy and its types.
Enlist indications of hysterectomy.
Explain myomectomy, cervical cerclage, dilation& curettage , hysteroscopy,
vaccum aspiration.
748
39- REP 2 Obg 39Instrumental vaginal Delivery
Define Operative Obstetrics.

Describe different types of vaginal operations.
Enlist indications for vaginal operations.
Discuss complications of operative vaginal delivery.
Describe abdominal operations including LSCS.
40-REP 2 Obg 40Obstetrical emergency
Define Obstetrical Emergencies .

Describe types of obstetrical haemorrhage.
Enlist investigations for Obstetrical Emergencies .
Explain HELLP Syndrome.
Describe the causes for obstetrical haemorrhage.
Discuss the principles of managing obstetric emergencies
41-REP 2 Obg 41Peurperium Normal &abnormal
Define Puerperium.
Explain Physiology of the puerperium
Describe Clinical manifestaion of puerperium
Discuss Diseases of puerperium
Discuss management & treatment of diseases of puerperium.
42-REP 2 Obg 42Safe Motherhood, MDGs
Define Safe motherhood.

Enlist causes of maternal mortality.
Discuss prevention of maternal deaths.
Enlist high risk pregnancies.
Discuss minor & severe problems in high risk pregnancies.
43-REP 2 Obg 43Obstetric Statistics: MMR,PNMR
Define maternal death and MMR.

Major causes of maternal mortalities in Pakistan.
Describe PERINATAL STATISTICS.
Define Perinatal mortality rate.
749
GENERAL SURGERY
1- REP 2 Sur 1STIs in males: MGT including Epididimytisorchitis, prostatitis
EnlistSTIs caused by various organisms.

Describe the pathogenesis of STIs of MGT.
Enlistrelevant lab. Diagnostic tests
Discuss management and treatment of STIs.
2- REP 2 Sur 2 Testicular tumors management
Describeclassification of testicular tumors.

Describemorphology of different testicular tumors.
DescribeClinical features of germ cell testicular tumors.
DescribeClinical staging of testicular tumours.
DescribeDifferenttumour markers.
Establish Diagnosis and management of testicular tumors.
3- REP 2 Sur 3 Diseases of Breast Diagnosis and management
DescribeNormal anatomy of breast.

DescribeLymphatic drainage of breast.
DescribeClassification of breast tumors
Explain Grading and staging of breast tumors.
Differentiate b/w benign and malignant lesions with common presentations
Different modalities and treatment options for these lesions.
PEDRIATRIC SURGERY
1- REP 2 Peds Sur 1Congenital abnormalities with diagnoses and management options
Define various congenital anomalies.

Explain clinical presentations of congenital anomalies.
Discuss treatment and management of various congenital anomalies.
750
PEDRIATRICS
1- REP 2 Ped 1Puberty & disorders of puberty
Define puberty and describe Tanner staging.

Enumerate the causes of precocious puberty.
Enlist the investigations for precocious puberty
Discuss the management and treatment of precocious puberty
2- REP 2 Ped 2Clinical presentation , complications and out line of management of

IUGR baby
Define Intra Uterine Growth Restriction

Discuss maternal l and fetal risk factors for Small for gestational age(SGA
Describe Foetal growth restriction
Discuss diagnosis and management of IUGR.
3- Rep 2 Ped 3Prematurity
Define prematurity.
List the causes of prematurity.
Assess gestational age at birth.
Explain problems related to prematurity.
Discuss the prevention , management and prognosis of prematurity.
4-REP2 Ped 4Neonatal Jaundice
Explain physiology of neonatal jaundice.

Explain pathology of neonatal jaundice.
Discuss the clinical features of kernicterus.
Describe prevention of hyperbilirubinemia.
Discuss the diagnosis and management of kernicterus.
5-Rep 2 Ped 5Infant of Diabetic mother
Define gestational diabetes.

Explain pathophysiology of gestational diabetes.
Describe the fetal effects of maternal diabetes.
Describe the clinical presentation and specific disorders of IDM at birth.
Discuss diagnosis and management of IDM.
6- Rep 2 Ped 6Neonatal Sepsis
Define neonatal sepsis.

Describe clinical presentation of neonatal sepsis.
Discuss the risk factors for neonatal sepsis.
Discuss the diagnosis , management and treatment of neonatal sepsis.
751
7-REP 2 Ped7Birth asphyxia
Define birth asphyxia.

Explain pathophysiology of birth asphyxia.
Explain clinical staging of HIE.
Describe systematic complications of HIE.
Discuss diagnosis and management of HIE.
8- REP 2 Ped 8Neonatal Resuscitation
Assess neonatal resuscitation.

Explain initial management of neonatal resuscitation.
Describe devices use for neonatal resuscitation.
Discuuss management of neonatal resuscitation.
9-REP2 Peds 9Respiratory Distress In Newborn
Explain signs of respiratory distress in new born.

Assess the new born with life threatening condition.
Discuss the differential diagnosis of respiratory distresss.
Discuss management of respiratory distress in newborn in various conditions.
10-Rep 2 Ped 10Breast feeding and lactation Problems associated with lactation in mothers
Explain method to start breast feeding

Discuss advantages of breast feeding.
Describe ten steps for breast feeding
Describe common problems associated with breast feeding.
Explainsolutions if baby refuses to feed.
Describe various breast feeding positions in special situations.
MEDICINE
1- REP 2 MED1Cardiac Diseases In Pregnancy
Describe Normal Physiological Changes in Pregnancy

Describe basic cardiac diseases in pregnancy
Discuss high risk cardiac lesions in pregnancy
Discuss drug categories of pregnancy
Discuss treatment and management of various cardiac diseases in pregnancy
752
Sbl 1
Discuss pathophysiology of PCOS
Discuss the long term consequences of PCOS
Explain management poly cystic ovarian disease
Sbl 2
Perform clinical assessment of female factors in infertility, by history and
examination of female.
Perform clinical assessment of male factors in infertility, by history and
examination of husband
Describe relevant investigations for female.
Describe relevant investigations for male.
Describe causes of infertility
Sbl 3
Recognize the causes of collapse in obstetric patient
Discuss the prevalence and types of post-partum haemorrhage
Recognize risk factors related to PPH
Analyze the clinical findings to find the cause of PPH
Interprete lab reports in a patient with hemorrhage
Discuss the complications in a patient with neglected PPH
Discuss the emergency management of obstetric patient with collapse
Outline the measures required to control PPH & management following that
Discuss means to prevent PPH
753
EXAMINATION OF BREAST
The clinical breast examination (CBE) can be used either for screening (to detect breast cancer
in asymptomatic women) or for diagnosis (to evaluate women who present with breast
complaints).
Students often avoid examination of the breasts during routine physical exam because of
shyness. It should be an essential part of routine physical examination for early detection of
breast disease.
At the end of this session students should be able to:
1. Demonstrate the proper technique of clinical breast examination.
2. Demonstrate the examination of axillary and supraclavicular lymph nodes.
3. Identify the findings in following abnormalities.
c. Fibro adenoma
d. Carcinoma
754
Total ROUND
WEEKS/HOURS 1st 2nd 3rd 4th 5th 6th 7th 8th including OFF For
practical *** Paper 3
ANATOMY 3.5 - - - - - - - 3.5 2.96 3
PHYSIOLOGY 2.5 - - - - - - - 2.5 2.11 2
PATHOLOGY 2.5 3.5 2 5 6 5 2 1.5 27.5 23.30 23
MICROBIOLOGY - 1 - - - - - - 1 0.84 1
GYNAECOLOGY\
- 4 7 9 5 5 8 9 47 39.49 39+4
OBSTETRICS
PHARMA. - 1.5 1 - - - - - 2.11 2
2.5
GEN. SURGERY - 1 - 1 - 2 - - 4 3.38 3+3
PEADS - - 1 - - 1 3 7 12 10.0 10+4

MEDICINE - - - - - - 1 - 1 0.84 1
COMM -
- - - 2 1 2 1 6 5.04 5
.MEDICINE
SKILL LAB 1.5 - - 1.5 - - - - 3 2.54 3
TOTAL 1 10 12.5 11 18 14.5 15.5 16 21.5 119 100.2 100
Total 2 for - 3
- 1.5 - 1.5 1.5 1.5 9 7.62 8
SBL
755
REPRODUCTIVE 2 MODULE -2 MODULE
(SEMESTER-VII)
THEORY

SEMESTER
ATP 25
EXAM
PAPER-III 80%
One best Questions
20
based on CBL
Total 100
MODULE EXAM
EMQs 10
ATP 20
MODULE PAPER 20%
One best Questions
20
based on SBL
Total 100
STRUCTURED VIVA

SUMMATIV
ASSESME
SEMESTE
R EXAM
See Semester
NT

E
Assessment Plan
ASSESSMENT TOOLS
Structured Feedback
Facilitator
Paper II & IV-B of Semester-7 Examination are Based on Reproductive Syst.-2 Module.
756
CREDIT HOURS
SEMESTER VII
REPRODUCTIVE 2 MODULE
Paper-III 5
REPRODUCTIVE
Paper-IV C 2.5
757
CREDIT
HOURS
ENT / EYE Module

40 Marks
I ENT / EYE Module
Marks 3
10 Marks
(Module Exam)
Orthopedics-2 Module
60 Marks
II Orthopedics-2 Module
15 Marks
Marks 4
(Module Exam)
Reproductive-2 Module
72 Marks
III Reproductive-2 Module
18 Marks
Marks 5
(Module Exam)
ENT / EYE-2 Module

a
(Viva)
25 Marks 1.5
100
IV b
Orthopedics-2 Module
(Viva)
33 Marks Marks 2.0
Reproductive-2 Module
C
(Viva)
42 Marks 2.5
758
759
SEMESTER -8
EYE-II Module 3 Weeks 4.5 Credit Hours
Rehamatology &
Rehabilitation Module 2 Weeks 1.5 Credit Hours
Dermatolgoy Module 2 Weeks 1.5 Credit Hours
Genetics Module 1 Weeks 1.5 Credit Hours
Neuroscieces Module 8 Weeks 9 Credit Hours
760
OPHTHALMOLOGY (EYE) MODULE
Code: (EYE-2)
Semester:VII/VIII
Fourth Year MBBS
761
Spiral Sem. Modules

II

4 Week
wks
Second th
Spiral th
Trauma, 6 week
3 week 8 Weeks
/ Burns 2 wk
2 Weeks
th
th
IX & In Medicine, Pediatrics, Cardiology and Neurology units Operation Theatres)
Third X
Lecture on problem based approach, twice a Neurosurgery. 1:30 to 3:00 pm
Spiral week Lecture on problem based
PARALLEL THEMES:
762
MODULE COMMITTEE
Prof. Dr Salahuddin Afsar, Professor of Medicine, DUHS.
Prof.Dr.Shahid Wahab, Professor of Ophthalmolgy, DUHS.
Prof. Dr.Muneer Quraishi, Professor of OphthalmolgyDUHS.
Dr. Abdul Rasheed , Associate Professor of OphthalmolgyDUHS.
Prof.Dr. Shafiq Ali Baig, Professor of Ophthalmolgy, DUHS.
Dr. Shehla Dareshani, Assistant Professor of Ophthalmolgy, DUHS.
Dr. Rukhsana Rubeen, Associate Professor of Biochemistry, DUHS.
Module Coordinator:
DR. SAIMA RASHID
Documented by:
DR SAIMA RASHID
763
RATIONALE:
Disorders of Eye are commonly encountered in medical practice. A medical graduate must
be able to understand common diseases affecting the eye and related structures including
ocular trauma as well as have a sound knowledge of systemic diseases affecting the eye.
Common diseases which affect eye include infections such as conjunctivitis, cataract,
glaucoma, retinal diseases, errors of refraction and involvement of eyes in systemic
disorders. Understanding the principles of fundoscopy is also essential for a doctor. In this
module these diseases are discussed and the student shall be able to dwell on the basic
knowledge acquired in the Head and Neck module.
After completion of MBBS course the student should be able to:
Discuss the anatomy of eye and orbit

Revise the physiology of vision and optics and the pharmacology of ocular drugs
Discuss the pathophysiology diagnosis management of cataract and glaucoma
Identify the errors of refraction and discuss their management
Demonstrate the clinical significance of neuroophthalmology
Explain the role of laser in the management of eye disorders
Assess the complications development in eyes due to diabetes mellitus
764
Lectures
Demo:
Tutorials
Practical
CBL
spottin
Self Study
Digital library
BCQs, EMQs
ATP
Viva
Skills Lab
Objectives
Teaching
Content / Topic
Faculty
EYE 2 Ang 1 Revisit 1 * *

Describe the Anatomy Anatomy of the
Basic Orbit: Bones and
Anatomy &
Contents (Eyelid,
Physiology Of
Eye lacrimal apparatus,
orbital fascia,
muscles, nerves,
Blood vessels of
orbit, II, III, IV, VI
cranial nerves)
Physiology EYE 2 Phy 1 Review 1 * *

the basic physiology
of eye and principles
of optics
Diagnose the EYE 2 Oph 1 1 * *
basic DISORDERS OF
management Eye LACRIMAL
of
DRAINAGE SYSTEM
Dacrocystitis 1
EYE 2 Oph 2 * *
and NLDB
Acute/chronic
dacrocystitis/ NLDB
in infants
EYE 2 Oph 3 1 * *
Evaluation of
epiphora, congenital
NLDB.
765
EYE 2 Oph 4 1 * *
Treatment of
lacrimal obstruction
Recognize lid Eye EYE 2 Eye 5 LID 1 *
abnormalities ABNORMALITIES: *
and their Benign Eyelid Lesions;
management Stye
Chalazion
Molluscum
Contagiosum
Blepharitis
EYE 2 Eye 6 1 * *
DISORDERS OF
EYELASHES;
Trichiasis
Entropion
Ectropion
Ptosis
EYE 2 Eye 7 1 * *
MALIGNANT EYELID TUMOR;
Basal cell carcinoma
Squamous cell
carcinoma
Kaposi sarcoma
Diagnose and Eye 2 Eye 8 1 * *
manage Eye CONJUNCTIVA
conjunctival Viral Conjunctivits
eye problems Bacterial Conjunctivitis
Ophthalmia
Neonatorum
Pterygium-Pingecula
Trachoma
Vernal Catarrh
Keratoconjunctivitis
Sicca
EYE 2 Eye 9 1 * *
Diagnose and Eye CORNEA
manage Corneal ulcer
common (viral/bacterial/fungal)
corneal Keratomalacia
diseases Contact lens related
problems
Corneal degeneration
Corneal dystrophies
Keratoplasty
766
Diagnose and EYE 2 Eye 10 2 * *
Manage Eye CATARACT:
Cataract
problems. Definition
Classification
Causes
When to Operate
Management of age
related cataract and
different Options
IOL Options
EYE 2 Eye 11 2 * *
Diagnose Eye GLAUCOMA:
Manage Classification of
Glaucoma Glaucoma:
Primary/Secondary
Acute Angle Closure
Glaucoma and its
management
Chronic Open And
Chronic Closed Angle
Concept of IOP, Optic
Nerve Perfusion and
Disc Cupping
Diagnosis of Glaucoma * *
Glaucomatous Field
Changes, OCT, HRT
Broad Principles Of
Management
EYE 2 Eye 12 1 * *
Diagnose and Eye ORBIT
Manage Clinical Evaluation Of
different of Orbital Diseases
Diseases of Thyroid Eye Disease
the Orbit Orbital Infection And
Inflammation
Preseptal Cellulitis
Orbital Cellulitis
EYE 2 Eye 13 1 * *
Diagnose and Eye UVEITIS/IRITIS
Manage of Broad classification of
Uveitis and uveitis
Iritis Clinical features of
uveitis
Acute and chronic
uveitis
Management of uveitis
767
EYE 2 Eye 14 1 * *
Diagnose and Eye EPISCLERITIS AND
Manage of SCLERITIS
Episcleritis Definition
and Scleritis Classification
Clinical feature
Treatment
EYE 2 Eye 15 2 * *
Discuss Eye REFRACTIVE ERRORS
refractive AND TREATMENT
errors by Myopia
applying the Hypermetropia
principles of Presbyopia/
optics Pseudophakic
presbyopic lens
* *
Astigmatism/
pseudophakic toric
Contact lens
Different types of
spectacle lens/ bifocal/
progressive glasses
PRK, LASIK.
EYE 2 Eye 16 1 * *
Diagnose Eye
visual field NEUROOPHTHALMOLOGY
defects and Pupillary, Visual field
explain visual pathway and
pathology
pathway
RAPD
cranial nerves Cranial nerve palsies:
and CN III, IV, VI
extraocular Extra ocular
movements movements
EYE 2 Eye 17 1 * *
Describe the Eye OPTIC DISC:
optic disc Optic neuritis
disorders Papilloedema
Optic atrophy
EYE 2 Eye 18 1 * *
Enlist the Eye
complications DIABETES AND THE EYE
in the Diabetic
Eye and
discuss
management
EYE 2 Eye 19 2 * *
Diagnose the Eye MEDICAL RETINA
retinal Hypertension
pathologies Central retinal artery
occlusion (including
giant cell arteritis)
Central/ branch vein
occlusion
ARMD
768
Peripheral retinal
degeneration
EYE 2 Eye 20 1 * *
Describe the Eye SURGICAL VITREO-
vitreo-retinal RETINA
procedures Basic concept of vitreo-
retinal surgery
Explain the Basic pathophysiology
basic concept of and clinical concept,
retinal presentation and
detachment broad principles of
management of retinal
Discuss the detachment
management of Vitreous hemorrhage
vitreous Management of
hemorrhage Diabetic Retinal
and diabetic Complications
retinal
problems
EYE 2 Eye 21 2 *
Explain the Eye DIFFERENTIAL *
concept of early DIAGNOSIS OF
childhood LEUCOCORIA IN A
ocular diseases CHILD
CONGENITAL
CATARACT AND ITS
* *
MANAGEMENT
* *
RETINOBLASTOMA
ROP * *
CONGENITAL * *
GLAUCOMA AND ITS
MANAGEMENT
STRABISMUS
* *
EYE 2 Eye 22 1 * *
Recognize the Eye
indication and PHARMACOLOGY OF
systemic and OCULAR DRUGS WITH
local side SIDE EFFECTS
effects of ocular Local anesthetic drugs
drugs Antibiotics
Antiviral
Steroids
Antiglaucoma
Mydriatics
Lubricants
Steven Johnsons
Syndrome
769
EYE 2 Eye 23 2 * *
Recognize of Eye
eye problems Connective Tissue
associated with Disorders
systemic Dry Eye And Its
diseases Management
Systemic Diseases
Affecting The Eye
Acquired Immune
Deficiency Syndrome
(AIDS)
T.B/Sarcoidosis
EYE 2 Eye 24 1 * *
Define the Eye Definition of Blindness
Epidemiology (WHO)
of blindness
and awareness Epidemiology Of
of low visual Blindness
aids
Blindness And Low
Visual Aids
Eye EYE 2 Eye 25 2 * *

Discuss the
Trauma (Blunt, Fracture of the orbit
Penetrating, Penetrating injuries of
Perforating, the eye
Chemical Perforating injuries of
Injury) and the eye
describe basic Blunt injuries of the
the orbit and eye
management Chemical injuries
Acid burns
Alkaline burns
Eye EYE 2 Eye 26 2 * *

Explain the Lasers and the Eye
Effects of laser
EYE Skill Lab EYE 2 skl 1 * *

EXAMINATION Direct 1.5
Ophthalmoscopy
EYE 2 Eth 1
ETHICS Describe
a) MEDICAL
bioethics,medical 1.5 * *
ETHICS
ethicsand practical
ethics.
770
b) DECISION EYE 2 Eth 2
ETHICS Describe types of
MAKING 1.5 * *
CAPACITY informed consent
EYE 2 Eth 3
Describe rules of
c) DESCRIBE Ethics regarding 1.5 * *
RESEARCH ETHICS ETHICS research
EYE 2 Eth 4
Describe respect for
d) PRIVACY Autonomy,Privacy
ETHICS 1.5
and its types
,define
Confidentiality.
EYE 2 Eth 5
ETHICS
Describe Human
rights ,the rights of
e) THE RIGHTS
the patient , its 1.5 * *
OF PATIENT
importance and
describe the duties
of physicians.
771
EYE 02 MODULE
TIME TABLE
FIRST WEEK
Days 08:30 to 09:30 09:30 to 10:30 10:30 to 1:00 1:30 to 03:00
ANATOMY EYE
1 Review of Anatomy of Lid CLINICAL MEDICAL ETHICS
the Eye and Orbit NAME OF FACULTY
Abnormalities POSTING VENUE
NAME OF FACULTY
VENUE
2 Public Holiday
EYE
Acute/Chronic
Dacrocystitis/ NLDB In EYE CLINICAL ETHICS
3 Conjunctiva Decision making capacity
Infants POSTING
NAME OF FACULTY VENUE NAME OF FACULTY VENUE
NAME OF FACULTY
VENUE
EYE EYE ETHICS

CLINICAL
4 Cornea Cataract-I
POSTING NAME OF FACULTY VENUE
VENUE VENUE
EYE
5 Cataract-II CLINICAL POSTING
NAME OF FACULTY
VENUE
EYE
EYE
Glaucoma CLINICAL ETHICS
6 Glaucoma
NAME OF FACULTY POSTING NAME OF FACULTY VENUE
VENUE
772
EYE 02 MODULE SEMESTER VII
Time Table Week-2
Days 08:30 to 09:30 09:30 to 10:30 10:30 to 1:00 1:30 to 03:00
GP=A1, SBL-1 (Ward EYE-I)
GP= A2, SBL-2 (Ward EYE-
EYE II) NAME OF FACULTY VENUE
EYE
1 CLINICAL GP=A3, Digital Library
Uveitis/ Iritis
Episcleritis and Scleritis POSTING
NAME OF FACULTY GP=A4, Physiology Practical
VENUE revist Error of Refraction and
Visual acquity VENUE
GP=A5, SELF STUDY
PHYSIOLOGY 6. A2
EYE CLINICAL 7. A3
Physiology of Vision
2 Refractive Errors 8. A4
and Optics POSTING
10. A1
EYE 6. A3
EYE 7. A4
CLINICAL
3 Neuroophthalmology POSTING 8. A5
Optic Disc
9. A1
6. A4
EYE EYE CLINICAL 7. A5
Medical Retina Medical Retina POSTING 8. A1
4
NAME OF FACULTY VENUE NAME OF FACULTY VENUE 9. A2
10. A3
EYE
CATARACT-II
VENUE
6. A5
EYE EYE 7. A1
6 CLINICAL
Lasers And The Eye Diabetes And The Eye 8. A2
POSTING
10. A4
773
SEMESTER VII
EYE 02 MODULE
Time Table Week-3
Days 08:30 to 09:30 09:30 to 10:30 11:00 to 1:00 1:30 to 03:00
GP=A1, SBL-1 VENUE NAME OF
FACULTY
EYE EYE GP= A2, SBL-( VENUE NAME OF
Childhood Ocular Childhood Ocular FACULTY
1 CLINICAL
Diseases Diseases POSTING GP=A3, Skill Lab Opthalmoscopy
GP=A4, Examination of EYE
VENUE VENUE
VENUE
GP=A5, SELF STUDY
EYE EYE 1. A2
Systemic Diseases And Systemic Diseases CLINICAL 2. A3
2 And The Eye 3. A4
The Eye POSTING
NAME OF FACULTY 4. A5
NAME OF FACULTY VENUE VENUE 5. A1
EYE 1. A3
EYE CLINICAL 2. A4
3 Trauma And The Eye Trauma And The Eye POSTING 3. A5
NAME OF FACULTY VENUE NAME OF FACULTY
VENUE
4. A1
5. A2
1. A4
EYE EYE
Surgical Vitreo-Retina CLINICAL 2. A5
4 Pharmacology Of Ocular 3. A1
Drugs NAME OF FACULTY POSTING
VENUE 4. A2
5. A3
EYE
Extra Ocular Movements 9:30 12:00
5 Strabismus CLINICAL POSTING
NAME OF FACULTY
VENUE
EYE 1. A5
EYE
Blindness And Low Visual 2. A1
6 Orbit CLINICAL
3. A2
Aids NAME OF FACULTY POSTING
4. A3
5. A4
774
LEARNING OBJECTIVES
THE END OF THE LECTURE THE STUDENT SHOULD BE ABLE TO
ANATOMY
1) EYE 2 Ang 1 REVIEW THE ANATOMY OF THE EYE BALL AND ORBIT
Discuss the bony orbit and its boundaries
Enumerate the extraocular muscles and their nerve supply
Explain the actions of extraocular muscles
Describe the eye ball and its coats.
PHYSIOLOGY
1) EYE 2 Phy 1 REVIEW THE BASIC PHYSIOLOGY OF EYE AND PRINCIPLES OF

OPTICS
Describe Functional anatomy of eye ball
Explain the accomadation and error of refraction
Identify the formation and circulation of AQUEOUS HUMOR
Enumerate the organization of retina
Discuss theVisual pathways
Describe visual acuity
OPHTHALMOLOGY
1) EYE 2 Eye 1 DISORDERS OF LACRIMAL DRAINAGE SYSTEM
Explain the disorders of lacrimal drainage

Identify the causative agents regarding disorders of lacrimal drainage
system
Describe the disorders of lacrimal drainage
775
2) EYE 2 Eye2 ACUTE/CHRONIC DACROCYSTITIS LACRIMAL DRAINAGE
SYSTEM / WATERY EYES
Approach to the patient with watery eyes
Enlist the different causes of watery eyes, acquired/congenital.
Discuss the clinical examination with investigation of watery eyes (acute and
chronic Dacryocystitis.
Desribe the management of watery eyes.
3) EYE 2 Eye3 EVALUATION OF EPIPHORA, CONGENITAL NLDB.
o Explain Epiphora.
Diagnose Congenital NLDB.
Describe its clinical features and management.
4) EYE 2 Eye 4 Treatment of Lacrimal Obstruction
Descibe the Lacrimal Obstruction.

Discuss the treatment of the Lacrimal Obstruction
5) EYE 2 Eye 5 EYE LID DISORDERS
Drescribe the infective lesions of lid -stye/blepharitis and their treatment

Enlist the inflammatory lesions of lid like chalazion and their treatment
Discuss the common lid tumors and their clinical presentations.
6) EYE 2 Eye 6 EYE LASHES DISORDERS
Discuss the Eye - Lash abnormalities.

Describe the pathologies like Trichiasis ,ectropion / entropion and ptosis.
7) EYE 2 Eye 7 MALIGNANT EYELID TUMOR;
Describe Basal cell carcinoma, Squamous cell carcinoma, Kaposi

sarcoma.
Explain the management of Basal cell carcinoma, Squamous cell
carcinoma, Kaposi sarcoma.
8) EYE 2 Eye 8 CONJUNCTIVA

Classify this disorder
Enlist common causes, sign and symptoms of conjunctival disorders.
Diagnose the conjunctival eye problems.
Discuss the management of conjunctival eye problems
776
9) EYE 2 Eye 9 CORNEA/KERATITIS
Approach patient with keratitis
Enlist the causes,its classification and sign and symptoms .
Discuss the clinical examination including the different stains used for staining
the corneal ulcers
Describe the treatment of corneal ulcers
Explain the contact lens related keratitis with its management
10) EYE 2 Eye 10 CATARACT :

Define cataract
Enlist classification of cataract,
Discuss theclinical examination with investigations to diagnose .
To approach patient with leucocoria and its differential diagnosis.
Explain the principles of management of cataract.
11) EYE 2 Eye 11 GLAUCOMA:
Approach patient with glaucoma

Define,and classify cataract.
Enlist the investigations to diagnose it.
Explain the principles of management of glaucoma.
Discuss the congenital glaucoma, presentation and treatment
12) EYE 2 Eye 12 ORBIT
Evaluate the Orbital Diseases ,Thyroid Eye Diseases, Preseptal Cellulitis,

Orbital Cellulitis ,Orbital Infection and Inflammation.
Approach patient with proptosis.
Discuss the differential diagnosis of proptosis.
Describe the dysthyroid eye diseases, clinical presentation and management.
Explain the common benign and malignant orbital tumors and their
management
13) EYE 2 Eye 13 UVEITIS/IRITIS
Approach patient with uveitis.

Describe the clinical features of uveitis
Enlist its classification, describe its clinical features ,sign and symptoms,
special investigations and general management of uveitis.
Differentiate between acute and chronic uveitis.
777
14) EYE 2 Eye 14 EPISCLERITIS AND SCLERITIS
Define Episcleritis and Scleritis

Classify Episcleritis and Scleritis
Explain its clinical feature andtreatment
15) EYE 2 Eye 15 REFRACTIVE ERRORS:

Approach patient with refractive errors: Myopia, hypermetopia, astigmatism
and their methods of correction.
Describe Presbyopia/ Pseudophakic presbyopic lens
Discuss Astigmatism/ pseudophakic toric
Explain Contact lens
Discuss different types of spectacle lens/ bifocal/ progressive glasses, LASIK
Enlist different refractive surgeries.
16) EYE 2 Eye 16 NEURO-OPHTHALMOLOGY

Explain the anatomy of visual field pathway.
Describe the visual field defect in the lesion of optic nerve.
Discuee the visual field defect in the lesion of optic chiasma.
Dignose the visual field defect in the lesion of post chiasmal lesion.
17) EYE 2 Eye 17 OPTIC DISC
Describe Optic neuritis and Papilloedema

Explain Optic atrophy
Discuss their clinical presentations and management.
18) EYE 2 Eye 18 DIABETES and the EYE
To approach a patient with Diabetes.

Describe its clinical features.
Discuss its management and its complications.
19) EYE 2 Eye 19 MEDICAL RETINA
Enlist the diabetic and hypertensive retinopathies.

Classify it .
Discuss its clinical features .
Describe thedifferential diagnosis and management according to the stage of
retinopathies.
Identify retinal arterial and venous occlusive diseases, their causes, clinical
features, differential diagnosis and treatment options.
778
Describe the related macular degeneration, their classification and
management according to the classification.
Enlist the causes of gradual and sudden loss of vision.
20) EYE 2 Eye 20 SURGICAL RETINA (RETINAL DETACHMENT)
Explain the basic concept of vitreo-retinal surgery

Define and classify of retinal detachment
Desctibe the basic pathophysiology and clinical concept, presentation and
broad principles of management of retinal detachment
Enumerate Vitreous hemorrhage.
Discuss the management of Diabetic Retinal Complications
21 EYE 2 Eye 21 EARLY CHILDHOOD OCULAR DISEASES and STRABISMUS:
Discuss Leucocoria (white pupillary reflex) its differential diagnosis.

Describe Retinoblastoma, its clinical presentation and management.
Explain Congenital cataract, presentation and management.
Enimerat retinopathy of prematurity, persistent hypertensive, primary vitreous,
coats diseases.
To approach patient with strabismus.
Classify, different clinical methods
Explain different surgical procedures of squint
22) EYE 2 Eye 22 PHARMACOLOGY OF OCULAR DRUGS
Describe the mechanism of action, indication and side effect of MIOTICS.

Classify (short and long acting) these drugs.
Discuss the mechanism of action, indication and side effect of MYDRIATICS.
Explain the mechanism of action and side effects of ANTIGLAUCOMA
DRUGS.
Enlist the ANTIBIOTICS its indication and their side effect
Enumerate the Indication and their side effect of STEROIDs
23) EYE 2 Eye 23 SYSTEMIC DISEASES AND EYE
Describe the Connective Tissue Disorders ,Dry Eye And Its

management.
Explain differtrent systemic iseases Affecting The Eye
Discuss the Acquired Immune Deficiency Syndrome (AIDS),
T.B/Sarcoidosis and common systemic infections.
779
24) EYE 2 Eye 24 BLINDNESS AND LOW VISION AIDS
Define of Blindness and WHO criteria

Enlist the common cause of blindness
Describe the low vision aids and overview of different type of low vision
aids.
25) EYE 2 Eye 25 TRAUMA TO EYE AND ORBIT
Define the terms related to trauma e.g: laceration, contusion

Dscribe the Blunt trauma and its ocular manifestation and its management
Explain the penetrating trauma including ocular foreign bodies : clinical
presentation and management.
Enlist the Chemical injuries i.e.: Alkali and acid burns :its clinical presentation
and management.
Discuss Orbital fracture especially Blow out orbital floor fracture, its clinical
presentation and management.
26) EYE 2 Eye 26 Lasers and the Eye

Describe Lasers and the Eye
Discuss the role of Lasers regarding management of eye disorders
ETHICS
1. EYE 2 Eth 1 MEDICAL ETHICS:

Describe bioethics,medical ethics,practical ethics.
2. EYE 2 Eth 2 DECISION MAKING CAPACITY:

Describe types of informed consent.
3. EYE 2 Eth 3 DESCRIBE RESEARCH ETHICS:

Describe Ethics.
4. EYE 2 Eth 4 PRIVACY:

Describe respect for Autonomy,Privacy,and its types define
Confidentiality.
5. EYE 2 Eth 5 THE RIGHTS OF PATIENT:

Describe Human rights ,the rights of the patient , its importance and
describe the duties of physicians.
780
EYE 2 Sbl 1
Describe the differential diagnoses of PAPILLOEDEMA
Enumerate the ophthamlic investigation.
Discuss complications if the condition is not treated
Outline the immediate medical treatment and OPD treatment
EYE 2 Sbl 2
Discuss the causes of a painful red eye
Discuss the causes of a painless red eye
Enumerate the differentiating clinical features of various causes of
conjunctivitis
Elaborate the treatment of various causes of conjunctivitis
LEARNING OBJECTIVE OF SKILLS LAB CURRICULUM
III. FUNDOSCOPY
Fundoscopy/Ophthalmoscopy is an examination of the back part of the eyeball (fundus),

which includes the posterior part of retina, optic disc and blood vessels with the help of an
ophthalmoscope. Fundoscopy is a non invasive procedure helpful in evaluating common
clinical symptoms like headache, visual defects, diabetes mellitus and hypertension.
After the session the student should be able to :
Identify the different parts of ophthalmoscope

Demonstrate the correct method of Fundoscopy.
Recognize the normal structures of fundus
Identify at least 6 pathological changes in fundus
1. Papilloedema
2. Optic disc Atrophy
3. Macular degeneration
4. Diabetic retinopathy
5. Hypertensive retinopathy
6. Optic disc Cupping
781
SUBJECT/TOTAL X
WEEKS/HOURS 1st 2nd 3rd TOTAL ROUND OFF
60
ANATOMY 1 - - 1 1.8 2
PHYSIO - 2.50 - 2.50 5 5
CLINICAL 8 9 11 28 50.9 50
Eye
- - 1.50 1.50 2.7
EXAMINATION 3
ETHICS 6 - 6 7.7 8
-
SBL - 3 3 6 7.7 8
SKILL LAB - - 1.50 1.50 1.9 2
TOTAL 15 14.50 17 46.50 74.7 75
782
EYE-2 MODULE
(SEMESTER-VIII)
THEORY

SEMESTER
ATP 25
EXAM
PAPER-I 80%
One best Questions
20
based on CBL
Total 100
MODULE EXAM
EMQs 10
ATP 20
MODULE PAPER 20%
One best Questions
20
based on SBL
Total 100
STRUCTURED VIVA

SUMMATIV
ASSESME
SEMESTE
R EXAM
See Semester
NT
PAPER-IV-A Structured viva

E
Assessment Plan
ASSESSMENT TOOLS
Structured Feedback
Facilitator
NOTE: Paper II & IV-B of Semester-8 Examination are Based on Phy Med /Gen / Derma Module.
Paper III & IV-C of Semester-8 Examination are Based on Neurosciences-2 Module.
783
CREDIT HOURS
SEMESTER III
EYE-2 MODULE
Paper-I 3
EYE-2
Paper-VI-A 1.5
784
.
REHABILITATION (PMR) MODULE

Code: (PMR-2)
Semester: VIII
Fourth Year MBBS
785
Spiral Sem. Modules

II

4 Week
wks
Second th
Spiral th
Trauma, 6 week
3 week 8 Weeks
/ Burns 2 wk
2 Weeks
th
th
Third X
PARALLEL THEMES:
786
MODULE COMMITTEE:

Prof Dr. Nabila Somroo , Professor and Director of IP&MR, DUHS
Prof Dr. Maratib Ali ,Professor of Orthopaedic Department. DUHS
Prof. Dr Naheed Khan , Professor of Anatomy, DUHS
Dr. Rukhsana Rubeen ,Associate Professor of Biochemist, DUHS
Module Coordinator:
DR. SAIMA RASHID
Documented by:
DR SAIMA RASHID
Reviewed by
Modular Committee
787
RATIONALE:
Undergraduate medical education has traditionally focused on curative

approaches to acute illnesses and injuries. Rehabilitation is the process of
helping a person to reach the fullest physical, psychological, social, vocational,
vocational, and educational potential consistent with his or her physiologic or
anatomic impairment, environmental limitations, desires and life plans.
This rehabilitation module provides the basic understanding of physical

therapy, occupational therapy and rehabilitation of patients along with the
social and psychological barriers faced by the disabled persons and the ways to
overcome these.
Define impairment, disability and handicap.

Assess, diagnose and discuss prevention disabilities
Describe the role of multidisciplinary rehabilitation team and responsibilities of each

member.
Identify rehabilitation management of common neurological, musculoskeletal and

cardiac problems.
Recognize the role of assistive technology in rehabilitation medicine.
Perform rehabilitation counseling of patient
788
BCQS, SEQS EMQS

WRITTEN ASSESS;
DIGITAL LIBRARY
SELF STUDY
TUTORIALS
PRACTICAL
LECTURES
SKILL LAB
LIBRARY
VIVA
ATP
SBL
REHABILITATION PMR Pmr 1

DEPTT Rehabilitation
medicine * * *
Describe the concept of
rehabilitation medicine 1

DEPTT Impairment ,
Define and distinguish disability and 1 * * *
between impairment, handicap
disability and handicap

DEPTT Rehabilitation
Describe the goal of Evaluation *
rehabilitative functional
evaluation is to restore
1.5 * *
handicapped people to
fullest possible physical,
mental,social & economic
independence

Diagnose, assess and DEPTT Assessment of
prevent disabilities. Disabilities 1.5 * * *
DEPTT Describe the role of
Discuss the rehabilitative rehabilitation team 1.5 * * *
management of stroke and responsibilities
of each member
regarding STROKE
patient.
789
Enlist active range of REHABILITATION PMR Pmr 6
motion exercises . DEPTT Rehabilitation of
Conditioning exercises of Amputee * *
non amputee extremities.
Muscle strengthening of 1.5
bilateral upper & lower
limbs
Explain the role of REHABILITATION PMR PMR 7

assistive technology in DEPTT Assistive * *
rehabilitation medicine Technology 1.5
Perform REHABILITATION PMR Pmr 8

Rehabilitation counseling DEPTT Rehabilitation
* *
of patients. Counseling
1.5
REHABILITATAION PMR Pmr 9

Replace parts lost by DEPTT UPPER LIMB PROSTHESIS
injury or missing from and LOWER LIMB
birth or to supplement PROSTHESIS
defective lower body
1.5 * * *
parts
Perform the attachment REHABILITATAION PMR Pmr 10

of body segment to DEPTT Management of
improve function by Fractures 1.5
controlling motion, * * *
providing support
through stabilizing gait.

Explain the postural DEPTT Management of
education to Osteoporosis
Avoid immobility,care
1.5
of fragile skeleton .
* *
Discuss the
Management of
Dietary measures and
Prevention of fall
application of
Orthotics

Formulate the rehab DEPTT Rehab management of
management of common neurological, * *
common neurological,
1.5
musculoskeletal and
musculoskeletal and cardiac problems
cardiac problems.
SCENARIO BASE PMR Sbl 1

LEARNING Talipes equinoveres
(ORTHOPAEDIC * *
1.5
DEPTT)
790
PATHOLOGY PMR Pth 1
Identify different types Pathological Fractures
of pathological fractures (PRACTICAL) 1.5 *
*
SCENARIO BASE PMR Sbl 2

LEARNING OPEN FRACTURE
ORTHOPAEDIC * *
DEPTT 1.5
COMMUNITY PMR Com 1

MEDICINE
To evaluate the public
health issues faced by
Evaluate the disabled and the
Public health issues policy makers. * *
1.5
COMMUNITY PMR Com 2

Discuss the MEDICINE Physical rehabilitation
Community baesd (TUTORIAL) 1.5 * *
physical and clinical
rehabilitation
PMR Com 3
Clinical based
*
Rehabilitation 1.5
791
RHEUMATOLOGY & REHABILITATION MODULE
TIME TABLE
FIRST WEEK, SEMESTER-VIII
Days 8:30 to 9:30 9:30 to 10:30 11:00 to 1:30 to 3:00

12:30
REHABILITATION IMPAIRMENT DISABILITY and Clinical COMMUNITY
Posting MEDICINE
6 MEDICINE HANDICAP
Name of Faculty
Name of Faculty venue Name of Faculty venue
venue
8:30 am to 10:00 am
1 A1= SBL Name of Faculty venue Clinical REHABILITATIO
A2= Visit to (IMP&R) P& O Department Posting N EVALUATION
Dr Madiha Zia
A3= Community Medicine (tutorial) Name of Faculty venue
venue
A4= PATHOLOGICAL FRACTURES Name of Faculty venue
A5= SELF STUDY
A5= SBL Name of Faculty venue ASSESSMENT OF
A1= Visit to (IMP&R) P& O Department DISABILITIES
28 DR SYED IMRAN
A2= Community Medicine (tutorial) Name of Faculty venue
AHMED
A4= SELF STUDY venue
A4= SBL Name of Faculty venue Clinical REHABILITATIVE
3 Posting
A5= Visit to (IMP&R) P& O Department MANAGEMENT
A1= Community Medicine (tutorial) Name of Faculty venue OF STROKE
DR SYED IMRAN
A2= PATHOLOGICAL FRACTURES Name of Faculty venue AHMED
A3= SBL Name of Faculty venue Clinical REHABILITATIO
4 Posting
A4= Visit to (IMP&R) P& O Department N OF
A5= Community Medicine(tutorial) Name of Faculty venue AMPUTEE
Name of Faculty
venue
A2= SELF STUDY
A2= SBL Name of Faculty venue Clinical
5 Posting
A3= Visit to (IMP&R) P& O Department
A4= Community Medicine(tutorial) Name of Faculty venue
A1= SELF STUDY
ASSISTIVE TECHNOLOGY Clinical SELF STUDY
6
Name of Faculty venue Posting
792
SEMESTER VIII: REHABILITATION MODULE
TIME TABLE WEEK: 2
Days 8:30 to 9:30 9:30 to 10:30 10:00 to 12:30 1:30 to 3:00
Rehabilitation
counseling UPPER LIMB PROSTHESIS Management of
1 Clinical
Name of Faculty Name of Faculty fractures-1
Posting
venue venue Name of Faculty
venue
08:30AM TO 10:00AM
A1+A5= SBL Name of Faculty venue
A2= Visit to (IMP&R) P& O Department Clinical LOWER LIMB PROSTHESIS
2
Posting Name of Faculty
A3= CM Name of Faculty venue
A2= SBL Name of Faculty venue REHABILITATIVE

A3= Visit to (IMP&R) P& O Department MANAGEMENT OF
Clinical
3 OSTEOPOROSIS
Posting
A4= CM Name of Faculty venue Name of Faculty
A1+A5= SELF STUDY venue
A3= SBL Name of Faculty venue Rehabilitation management

of common neurological,
A4= Visit to (IMP&R) P& O Department Clinical
4 musculoskeletal and cardiac
Posting
A1+ A5= CM Name of Faculty venue problems
A2= SELF STUDY Name of Faculty venue
A4= SBL Name of Faculty venue

A1+A5 Visit to (IMP&R) P& O Department
5 Clinical Posting
A2= CM Name of Faculty venue
A3= SELF STUDY
6
MODULE TEST
793
LEARNING OBJECTIVES
AT THE END OF THE LECTURE THE STUDENT SHOULD BE ABLE TO :
REHABILITATION
1. PMR 2 Pmr 1 REHABILITATION MEDICINE:

Diagnose and treat pain.
Restore maximum function lost through injury, illness or disabling conditions.
Treat the whole person, not just the problem area.
Lead a team of medical professionals
Provide non-surgical treatments.
Explain your medical problems , treatment and prevention plan.
Develop a comprehensive program for putting the pieces of a person's life
back together after injury or disease without surgery.
2. PMR 2 Pmr 2 IMPAIRMENT ,DISABILITY and HANDICAP:
Enumerate the terminologies like impairment, disability and handicap, are

replaced by more positive expressions health status, functional abilities,
and social participation.
Exercise physiology
Discuss the psychology of disability
Explain the management of a board array of medical and surgical problems
and the functional effects of these problems and associated physical
impairments .
Enumerate similarity with the knowledge and skills of the various members of
the rehabilitation team .
Implement the managerial skills necessary to direct teams and lead team
meetings.
3. PMR 2 Pmr 3 REHABILITATION EVALUATION

Describe the goal of rehabilitative functional evaluation.
Discuss the restoration of handicapped people to fullest possible physical,
mental, social & economic independence.
4. PMR 2 Pmr 4 ASSSESSMENT OF DISABILITIES:
Exercise physiology.
Discuss the psychology of disability.
794
Discuss the management of a board array of medical and surgical problems
the functional effects of these problems and associated physical impairements
.
Discuss the knowledge and skills of the various members of the rehabilitation
team .
Discuss the managerial skills necessary to direct teams and lead team
meetings.
5. PMR 2 Pmr 5 REHABILITATION MANAGEMENT OF STROKE:
Describe how to help a person to reach the fullest physical,

psychological, social, vocational and educational potential consistent
with his or her physiologic or anatomic impairment, environmental
limitations, desires and life plans.
6. PMR 2 Pmr 6 REHABILITATION AMPUTEE:

Exhibit the active range of motion exercises.
Explain the conditioning exercises of non- amputee extremities
Describe muscle strengthening of bilateral upper & lower limbs
Demonstrate manual muscle testing.
Ambulate with assistive devices
Council patient & family assessment about vocational activities.
7. PMR 2 Pmr 7 ASSISTIVE TECHNOLOGY:
Evaluate functionally in their environment

Describe how to select, design, customize, adapt, apply, retrain ,repair&
replace AT devices
Discuss thePurchase or lease of AT.
Co-ordinate AT devices use with rehabilitation programs.
Train a family member person using AT& other rehabilitation professionals.
8. PMR 2 Pmr 8 REHABILITATION COUNCELLING:

Counsel a patient , based on a relationship that is built on empathy,
acceptance and trust. Within this relationship, the counselor focuses on the
clients feelings, thoughts and actions, and then empowers clients to:
Cope with their lives.
Explore options.
Make their own decisions.
Take responsibility for those decisions.
795
9. PMR 2 Pmr 9 UPPER AND LOWER LIMB PROSTHESIS :
Demonstrate that a prosthesis must be comfortable to wear, easy to

put on and remove, lightweight, durable, and cosmetically pleasing.
Describe that how a prosthesis must function well mechanically and

require only reasonable maintenance.
10.PMR 2 Pmr 10 REHABILITATIVE MANAGEMENT OF FRACTURES:

Describe that how a lower limb orthosis is an external device applied or
attached to lower body segment to improve function by controlling motion,
providing support through stabilizing gait, reducing pain through transferring
load to another area ,correcting flexible deformities.
Explain Prevention of progression of fixed deformities .
11.PMR 2 Pmr 11 REHABILITATIVE MANAGEMENT OF OSTEOPOROSIS:

Explain postural education
Describe how to avoid immobility
Discuss the care of fragile skeleton by ADL equipments
Explain dietary measures
Describe the prevention of fall
Identify the use of Orthotics
12.PMR 2 Pmr 12 REHABILITATIVE MANAGEMENT OF COMMON

NEUROLOGICAL,MUSCULOSKELETAL AND CARDIAC PROBLEMS
Describe the Rehabilitation management availability options regarding

neuromusculoskeletal and cardiac disorders.
Identify rehab management of common neurological disorders.
COMMUNITY MEDICINE
1. PMR 2 Com 1 COMMUNITY RELATED REHABILITATION
Explain the concept of REHABILITATION

Evaluate the public health issues faced by the disabled and the policy makers
.
Enlist the types of rehabilitation .
Review the statistics and legislation regarding the disabled and their
rehabilitation.
796
SCANERIO BASE LEARNIG
PMR Sbl 1 TALIPES EQUINOVERES
Define the condition
Enumerate the causes
Discuss the associated conditions
Describe the presentation of the condition
Enlist the management options
Explain the complications of the condition
PMR Sbl 2 COMPOUND FRACTURES
Classify open fractures.

Discuss the definitive management of injury.
Enlist the suggested level of amputation.
Describe Complications of amputation
Explain rehabilitate the patient.
797
SUBJECT/ ROUND
WEEKS/HOURS 1st 2nd Total
Total X 40 OFF
REHABILITATION 9.5 8 17.5 23.7 24
REHABILITATION
1.5 1.5 3 4 4
PRACTICAL VISIT
COMMUNITY MEDICINE 3 1.5 4.5 6.1 6
PATHO 1.5 _ 1.5 2 2
TOTAL FOR 2 SBL 4

1.5 1.5 3 4
TOTAL 17 12.5 29.5 39.8 40
798
PHYSICAL MEDICINE REHABLITAION-2 MODULE
GENETICS-2 MODULE
DERMATOLOGY AND PLASTIC SURGERY -2 MODULE
(SEMESTER-VIII)
THEORY

Phy Med Rehab BCQs 33
SEMESTE
R EXAM
PAPER-II Genetics BCQs 33 80%

Dermatology BCQs 34
Total 100
33
Phy Med Rehab BCQs
MODULE
EXAM
MODULE PAPER Genetics BCQs 33 20%

Dermatology BCQs 34
Total 100
STRUCTURED VIVA

SUMMATIV
ASSESME
SEMESTE
R EXAM
See Semester
NT

E
Assessment Plan
ASSESSMENT TOOLS
Structured Feedback
Facilitator
799
CREDIT HOURS
SEMESTER VIII
RHEUMATOLOGY & REHABILITATION MODULE
Paper-II-(i) 1
RHEUMATOLOGY &
REHABILITATION
Paper-IV-C - (i) 0.5
800
.
Dermatology & Plastic Surgery Module

Code: (DPS -2)
Semester:8
Fourth Year MBBS
801
Spiral Sem. Modules

II

4 Week
wks
Second th
Spiral th
Trauma, 6 week
3 week 8 Weeks
/ Burns 2 wk
2 Weeks
th
th
Third X
PARALLEL THEMES:
802
MODULE COMMITTEE:

Prof. Dr. Zarnaz Waheed, Professor and Head of Department of Dermatology, DUHS
Prof. Dr Naheed Khan , Professor of Anatomy, , DUHS
Dr.Prof Mahmood Hassan, Professor of Pathology Focal person , DUHS
Dr. Nadeem Alam, Associate Professor of Biochemistry , DUHS
Dr. Abdul Rauf Memon, Professor of Medicine , DUHS
Dr. Rukhsana Rubeen ,Associate Professor of Biochemistry, DUHS
Module Coordinator:
DR. SAIMA RASHID
Documented by:
DR SAIMA RASHID
Reviewed by
Modular Committee

803
RATIONALE:
Skin is the largest organ of the body. Its exposed position makes it susceptible to a
large number of disorders which include allergic conditions, infections, tumours and
involvement in metabolic disorders. Some of these require surgical management.
In this dermatology and Plastic surgery module the student shall gain the
understanding of skin diseases, their clinical presentation, diagnosis and their
management. The student shall also learn about the surgical aspects in the Plastic
surgery component.
SKIN
After completion of MBBS course the student should be able to:

Recognize the clinical presentations of common Skin diseases in the community.
Diagnose these diseases on the basis of history, examination and clinical
investigations.
Identify the preventive measures for counseling their patients.
Practice basic principles of management of common disease and make appropriate
referral.
Recognize of the prognosis to counsel their patients.
Be aware of the specific diagnostic tools for Skin diseases, and their interpretation.
PLASTIC SURGERY/BURNS
Medical graduates after completion of five years training program should be able to:
1. Enlist the type of skin and its behavior after injuries like pigmentation, hypertrophic
scar and Keloid.
2. Enumerate the relevant investigation in a given scenario including blood
investigations, relevant X-ray, Echo, CT and MRI scan.
3. Diagnose the type of wound and its management.
4. Enlist the different skin lesion and tumor and its management on the basis of local
and regional flaps.
5. Discuss the axial pattern flap for distant area coverage.
6. Explain the biological and artificial skin for coverage.
7. Describe the acute burn care.
8. Discuss how the graft applied
804
LEARNING OBJECTIVES OF THE MODULE:

Modes of information Transfer, duration of teaching of each content and
the mode of assessment
BCQS, SEQS EMQS

WRITTEN ASSESS;
DIGITAL LIBRARY
SELF STUDY
TUTORIALS
PRACTICAL
LECTURES
SKILL LAB
LIBRARY
VIVA
ATP
SBL
TOPIC/CONTENT
OBJECTIVES FACULTY
DPS Ang 1
General anatomy of
Identify the boundaries ANATOMY

skin
1 * * *
and divisions of
integumentary system
DPS Ang 2
Appendages of skin * * *
Identify the Appendages
of skin eg sebaceous 1
gland, eccrine, apocrine ANATOMY
glands and nails
DPS Anh 1
Identify the histology of HISTOLOGY OF SKIN * * *
epidermis, basement ANATOMY 1
membrane and dermis.
Describe the histological
terms and variant of skin
DPS Bio 1
Describe the role of
* * *
Biochemistry Elastin , collagen and 1
elastin collagen and
ground substance
ground substance
Discuss the nervous and DPS Phy 1

hormonal control of skin.
PHYSIOLOGY Physiological 1 * * *
functions of skin
Describe the
temperature regulation
and mechanical function
805
DPS Pth 1
Acute and chronic
inflammatory
Discribe the Acute and PATHOLOGY dermatoses 1
Chronic inflammatory * * *
Describe the Basic DPS Drm 1
Terminologies Of Skin
Identify the causes, DERMATOLOGY
Basic Terminologies 1 * * *
Of Skin
underlying pathology,
Scabies/Pediculosis
clinical presentation and
outline the management
of SCABIES
DPS Drm 2
Discuss different types of
BACTERIAL INFECTIONS DERMATOLOGY
Bacterial infections
And acne 1 * * *
Enlist the causes,
underlying pathology, Senerio base DPS Sbl 1
clinical presentation and learning Staphylococcal
outline the management scalded skin
syndrome 1.5
* * *
of ACNE
DPS Drm 3
ECZEMA 1
Describe the causes,
underlying pathology, DERMATOLOGY * * *
clinical presentation and
outline the management
of ECZEMA
Identify the causes, DPS Drm 4 1 * * *

Fungal Infections
DERMATOLOGY
and outline the
management of Fungal
Infections
DPS Sbl 2
SENERIO BASE Tinea capitis 1.5
LEARNING * * *
DPS Pha 1
Antifungal Treatment
Describe the
pharmacological PHARMACOLOGY 1 * * *
treatment of fungal
infection and discuss
806
Enlist the causes,
underlying pathology, DERMATOLOGY
DPS Drm 5
Viral Infection
* * *
1
and describe the
management of Viral
Infections
Discuss the causes, DPS Drm 6

underlying pathology, Psoriasis and Lichen * * *
Planus
clinical presentation DERMATOLOGY
and dignose the
management of
Psoriasis and Lichen 1
Planus
I
Explain the treatment DPS Pha 2
Treatment Of * * *
of Psoriasis
PHARMACOLOGY Psoriasis
1
DPS Pth 2
Describe the Bullous disorders * * *
PATHOLOGY ( blistering disorders)
pathogenesis and 1
management of bullous
disorders
( Blistering Disorders)
DPS Drm 7
Bullous disorders
DERMATOLOGY
(blistering
disorders)
* * *
1
Describe the Disorders of DPS Pth 3

Disorders of * * *
pigmentation pigmentation,
,melanocytes. melanocytes
1
PATHOLOGY
807
DPS Drm 8
Cutaneous Drug * * *
Discuss the causes,
DERMATOLOGY Reactions/
underlying pathology, 1
Urticaria and
clinical presentation and Pruritis
dignose the
management of Urticaria
And Pruritis
Identify the causes, DPS Drm 9
Cutaneous * * *
Manifestations Of
clinical presentation and `1
Systemic
discuss the management DERMATOLOGY Disorders
Cutaneous
Manifestations Of
Systemic Disorders
DPS Pth 4
Tumors of dermis * * *
Describe the
PATHOLOGY and epidermis
pathogenesis 1
of Tumors of dermis and
epidermis
DPS Pls 10
Discuss the management Management Of * * *
Plastic surgery Skin Tumors
of cutaneous malignancy
example BCC, SCC AND 1
Melanoma.
reconstruction after
tumor excision
DPS Pls 11
Burns
* * *
Plastic
Enlist different types, surgery/bruns.
1
Etiology, Pathophysiology
SENERIO BASE DPS Sbl 3
and its degree of Burns Burns
LEARNING
Chemical burns 1.5
DPS Pls 12
Management Of
* * *
Describe the Plastic surgery
Burns, Shock And
consequences of Burn 1
Burn Wounds
wound formation of scar
and contracture
808
DPS Pls 13
Special types of Burns
Discuss type of wounds
which require coverage
Plastic surgery * * *
1
DPS Pls 14
Skin Grafting And Skin * * *
Discuss how the scar and
Substitute
contracture formation is 1
Plastic surgery
reduced by physiology,
split, and graft.
DPS Pls 15
Enlist the type of flaps Flaps And Tissue * * *
Expander
graft SSG, FTG. 1
Plastic surgery
Describe where and
when it is applied.
SENERIO BASE DPS Sbl 4
LEARNING Flaps and tissue * * *
expanders
1.5
Discuss the DPS Pls 16

Common Cosmetic * * *
reconstruction after Plastic surgery Surgery
trauma and tumor 1
excision.
SKILL LAB DPS Skl 1 Suturing of 1.5
skin * * *
DPS Pls 17
Enlist different kind of Congenital * * *
anomalies and its time Plastic surgery Abnormalities
1
* *
of reconstruction
example cleft lip/palate
hypospadias, syndactly
Define SCABIES DPS Com 1
Explain its etiologic Scabies
agent 1 * * *
COMMUNITY
Describe the
epidemiology, control, MEDICINE
and prevention of
common skin diseases
Describe and discuss the DPS Com 2
different patterns of Fire arm injuries
COMMUNITY
Fire Arm Injuries. 1
Explain how domestic MEDICINE * * *
injuries can be prevented
Skin manifestations of DPS For 2
FORENSIC DERMATOLOGICAL * * *
different poisons can
MEDICINE MANIFESTATIONS IN 1.5
detect different poison
(TUTORIAL) CASES OF VARIOUS
POISONS
809
DERMATOLOGY-PLASTICS- MODULE
TIME TABLE
FIRST WEEK
Days 09:30 to 10:30 10:30 to 1:00 1:30 to 03:00

08:30 to 09:30
ANATOMY PHYSIOLOGY
General Anatomy of skin Physiological functions of skin HISTOLOGY OF SKIN
CLINICAL
1 NAME OF FACULTY VENUE
NAME OF FACULTY NAME OF FACULTY POSTING
VENUE VENUE
Skill lab: A2,a Self Study: A2.b

DERMATOLOGY
Basic Terminologies Of Skin - A3=SBL-1: Burns
ANATOMY Scabies/Pediculosis NAME OF FACULTY VENUE
Appendages of skin NAME OF FACULTY CLINICAL
2 A4= SBL-2, Derma Dr. Madiha VENUE
NAME OF FACULTY VENUE POSTING
VENUE A5= Histology of Skin: VENUE NAME OF FACULTY
A1= Forensic VENUE NAME OF FACULTY

PATHOLOGY DERMATOLOGY A4=SBL-1: Burns
Acute and chronic BACTERIAL INFECTIONS NAME OF FACULTY VENUE
inflammatory dermatoses AND ACNE (DERM) CLINICAL
3 A5= SBL-2, Derma Dr. Madiha VENUE
VENUE VENUE A1= Histology of Skin: VENUE
NAME OF FACULTY
A2= Forensic Medicine VENUE NAME OF FACULTY
A5=SBL-1: Burns
DERMATOLOGY NAME OF FACULTY VENUE
DERMATOLOGY Fungal
Eczema Infections CLINICAL
4 NAME OF FACULTY NAME OF FACULTY POSTING A1= SBL-2, Derma Dr. Madiha VENUE
VENUE VENUE
A2= Histology of Skin: VENUE NAME OF FACULTY
A3= Forensic Medicine VENUE NAME OF FACULTY
DERMATOLOGY CLINICAL
PHARMACOLOGY
Antifungal Treatment VIRAL INFECTION
5 NAME OF FACULTY
VENUE VENUE

DERMATOLOGY A1=SBL-1: Burns
Psoriasis And Lichen COMMUNITY MEDICINE NAME OF FACULTY VENUE
CLINICAL
6 Planus NAME OF FACULTY A2= SBL-2, Derma NAME OF FACULTY
POSTING
VENUE A3= Histology of Skin: VENUE
NAME OF FACULTY
A4= Forensic MedicineHALL 101 DR. PARTAB
810
DERMATOLOGY-PLASTICS MODULE
SEMESTER- 8, (4TH YEAR) TIMETABLE WEEK-2
10:30 to
Days 08:30 to 09:30 09:30 to 10:30 1:30 to 03:00
1:00
A1-B, SKILL LAB A1-A SELF STUDY
A2 SBL Burns, NAME OF FACULTY VENUE
PHARMACOLOGY PATHOLOGY
Mon Treatment Of Psoriasis
Bullous disorders CLINICAL A3 SBL DERMA NAME OF FACULTY VENUE
( blistering disorders) POSTING
16/9 NAME OF FACULTY A4- COLLAGEN & ELASTIN
NAME OF FACULTY
VENUE BIOCHEMISTRY VENUE
VENUE
A5=SKIN TUMORS: PATHO

DERMATOLOGY Pathology A3 SBL Burns, NAME OF FACULTY
Bullous Disorders Disorders of
Tues pigmentation, CLINICAL A4 SBL DERMA NAME OF FACULTY VENUE
NAME OF FACULTY
17/9 VENUE Melanocytes POSTING A5 COLLAGEN & ELASTIN
NAME OF FACULTY BIOCHEMISTRY VENUE
VENUE A1=SKIN TUMORS: PATHO
DERMATOLOGY Pathology A4 SBL Burns, NAME OF FACULTY VENUE
Cutaneous Drug Tumors of dermis and
Reactions/ Urticaria And epidermis CLINICAL A5 SBL DERMA NAME OF FACULTY VENUE
Wed
Pruritis POSTING A1= COLLAGEN & ELASTIN
18/9 NAME OF FACULTY NAME OF FACULTY BIOCHEMISTRY VENUE
VENUE VENUE A2=SKIN TUMORS: PATHO
DERMATOLOGY A5 SBL Burns, NAME OF FACULTY VENUE
PLASTIC SURGERY
Thur Cutaneous CLINICAL A1 SBL DERMA NAME OF FACULTY VENUE
Management Of Skin
19/9 Manifestations Of POSTING
Tumors A2- COLLAGEN & ELASTIN
NAME OF FACULTY
Systemic Dis
NAME OF FACULTY
BIOCHEMISTRY VENUE
VENUE
VENUE A3=SKIN TUMORS: PATHO
BURNS BURNS
Etiology, Management Of Burns,
CLINICAL
FRI Pathophysiology Of Shock And Burn POSTING
20/9 Burns Wounds
VENUE VENUE
PLASTIC SURGERY A5-B, SKILL LAB A5-A SELF STUDY
PLASTIC SURGERY Skin Grafting And Skin A1 SBL Burns, VENUE
CLINICAL
SAT Special types of Burns Substitutes POSTING A2 SBL DERMA NAME OF FACULTY VENUE
21/9 NAME OF FACULTY
NAME OF FACULTY
VENUE
VENUE
A3-- COLLAGEN & ELASTIN
BIOCHEMISTRY VENUE
811
DERMATOLOGY- PLASTICS BURNS MODULE
SEMESTER- 8, (4TH YEAR)TIMETABLE WEEK-3
10:30 to
Days 08:30 to 09:30 09:30 to 10:30 1:30 to 03:00
1:00
PLASTIC SURGERY
A1 SBL Burns, NAME OF FACULTY VENUE
MON Flaps And Tissue BURNS (CM) CLINICAL
23/9 Expander NAME OF FACULTY
POSTING A2 SBL DERMA NAME OF FACULTY VENUE
VENUE A3- VENUE
A4=SKIN TUMORS: PATHO NAME OF
FACULTY VENUE
PLASTIC SURGERY PLASTIC SURGERY

TUES
Common cosmetic Congenital CLINICAL
24/9 Surgery Abnormalities POSTING
VENUE VENUE
WED CLINICAL
25/9 POSTING
THUR
CLINICAL
POSTING
26/9
CLINICAL
FRI
POSTING
27/9
SAT
28/9 MODULE TEST
812
LEARNING OBJECTIVES
GROSS ANATOMY
1) DPS Ang 1 GENERAL ANATOMY OF SKIN
Define the term integumentary system

Discuss the function of the skin
Differentiate between epidermis and dermis
Discuss the significance of tension lines.
Discuss the main determinant of skin color
Identify the appendages of the skin
Differentiate between superficial and deep fascia
2) DPS Ang 2 APPENDAGES OF SKIN

Define the term Appendages of Skin
Discuss the structure of hairs, nails, sebaceous glands and sweat glands
Discuss the function of the hairs, nails, sebaceous glands and sweat glands
Describe the Sebaceous Glands:
Discuss the Eccrine Sweat Gland
HISTOLOGY
3) DPS Anh 1HISTOLOGY OF SKIN
Describe basic histology of skin.
Know the layers of Epidermis and Dermis.
Identify the different types of cell which are present in epidermis and
dermis.
PHYSIOLOGY
1) DPS Phy 1 PHYSIOLOGICAL FUNCTIONS OF SKIN
Discuss the nervous and hormonal control of skin.
Describe the temperature regulation and mechanical function
Explain the synthesis of vitamin D
813
PATHOLOGY
1. DPS Pth 1 ACUTE AND CHRONIC INFLAMMATORY DERMATOSIS
Enlist different types of acute and chronic dermatosis lesions
Explain urticaria
Discuss its morphology
Describe its pathogenesis
2. DPS Pth 2 BULLOUS DISORDERS ( BLISTERING DISORDERS)

Tumors of dermis and epidermis
Identify different types of skin tumors
Describe their morphology and pathogenesis
Explain different types of premalignant and malignant epidermal tumors.
Enlist different types of disorders of pigmentation and melanocytes
3. DPS Pth 3 DISORDERS OF PIGMENTATION, MELANOCYTES
Describe the role of melanin its morphology and pathogenesis

Explain melanoma
Discuss the pathogenesis of warts
Diagnose IMPETIGO ,MOLLUSCUM CONTAGIOSUM
4. DPS Pth 4 TUMORS OF DERMIS AND EPIDERMIS
Discuss the Tumors of dermis and epidermis

Describe their morphology and pathogenesis
Explain different types of pre -malignant and malignant epidermal tumors
PHARMACOLOGY
1. DPS Pha 1 ANTIFUNGAL TREATMENT
- Describe how they work
- Enumerate their clinical implications
- Enlist their classification
- Describe the mode of action of antifungal drugs
814
2. DPS Pha 2 TREATMENT OF PSORIASIS
- Explain mode of action methotrexate
- Discuss its pharmacokinetics ,side effects and toxicity
DERMATOLOGY
1) DPS Drm 1 BASIC TERMINOLOGIES OF SKIN -SCABIES/PEDICULOSIS
- Enlist its classification
- Identify different types of skin disorders including bacterial infections
- Describe Hyper keratosis ,erosions ulcers, scar, fissures, erythema and petechiae
- Describe Koebners Phenomenon Scabies
- Describe scabies
- Explain its clinical features
- Discuss Norwegian Scabies
- Describe the mode of transmission and its treatment.
Pediculosis
- Define pediculosis
- Describe different types of pediculosis
- Explain its clinical features
2) DPS Drm 2 BACTERIAL INFECTIONS AND ACNE (DERM)
Bacterial infections
Enlist different types of bacterial infections
Discuss their clinical features and diagnosis
Describe its treatment
Acne
Describe Acne
Enlist the causes of acne
Discuss its clinical features
815
Explain its treatment
Identify its complications
3) DPS Drm 3 ECZEMA

Define eczema
Describe different types of eczema
Explain exogenous eczema and endogenous
Discuss their clinical features investigations and treatment .
4) DPS Drm 4 FUNGAL INFECTIONS

Enlist different types of fungal infections
Discuss Tinea capitis, Tinea faciei, Tinea barbae, Tinea Corporis, Tinea Crusis, Tinea
Manum, Tinea Ungum, Tinea Pedis.
Describe their diagnosis and treatment.
5) DPS Drm 5 VIRAL INFECTION

Classify viral infections
Describe Herpes simplex, Trigeminal nerve zoster
Discuss its clinical features diagnosis treatment and complication
Explain Human Pappiloma Virus / Warts and Herpetic Gingivostomatitis
6) DPS Drm 6 PSORIASIS AND LICHEN PLANUS

Discuss the causes, underlying pathology, clinical presentation
Dignose the management of Psoriasis and Lichen Planus
7) DPS Drm 7 BULLOUS DISORDERS

Identify the etiology and epidermiology of bullous disorders
Describe its pathogenesis
Explain its clinical features &diagnosis
Discuss differential diagnosis
816
Enumerate the investigations
Discuss the treatment and its complications
8) DPS Drm 8 CUTANEOUS DRUG REACTIONS/ URTICARIA AND PRURITIS
- Define urticaria
- Enlist its classification
- Describe its pathophysiology
- Discuss the clinical features ,diagnosis and treatment
- Identify different drug reactions, Erythema Multiform and Stevens-Johnsons

Syndrome
9) DPS Drm 9 CUTANEOUS MANIFESTATIONS OF SYSTEMIC DISORDERS
Identify the causes, underlying pathology, clinical presentation

Discuss the management Cutaneous Manifestations Of Systemic Disorders
`10) DPS Drm 10 MANAGEMENT OF SKIN TUMORS
Discuss the management of cutaneous malignancy example BCC, SCC AND

Melanoma.
Describe the reconstruction after tumor excision
BURNS
1. DPS Drm 11 ETIOLOGY, PATHOPHYSIOLOGY OF BURNS
Enlist different types of Burns,its prevention.

Describe the Etiology, Pathophysiology and its degree
Describe the consequences of Burn wound formation of scar and contracture
2. DPS Drm 12 MANAGEMENT OF BURNS, SHOCK AND BURN WOUNDS
Tumors of dermis and epidermis

Describe their morphology and pathogensis
817
Explain different types of pre malignant and malignant epidermal tumors
3. DPS Drm 13 SPECIAL TYPES OF BURNS

Enlist major types of burns
Superficial / partial and full thickness of burns
Describe different systemic involvement of burns
PLASTIC SURGERY
1) DPS Drm 13 SKIN GRAFTING AND SKIN SUBSTITUTES
Differentiate between wound and ulcer

Enlist differnt types of wounds
Explain the basic principles of wound management.
Define Reconstructive Ladder.
Describe skin graft, its types, its uses, its procurement methods.
Enumerate the care of the graft donor site and stages involved in graft take.
Identify skin substitute, its types and different uses.
2) DPS Drm 14 FLAPS AND TISSUE EXPANDER
Define flap.
Differentiate between flap & graft.
Classify flaps according to blood supply, site , type of tissue and geometry.
Identify the Indications of flaps.
Explain the Care of the flap.
Define free flap?
Describe the tissue expander, principle on which it works and indications.
EnumerateZ plasty, its principle, uses and advantages.
3) DPS Drm 15 COMMON COSMETIC SURGERY
Define Cosmetic Surgery and Plastic surgery .

Differentiate between cosmetic surgery and Plastic surgery.
818
Know about history of Plastic surgery and cosmetic surgery, and the different non
invasive cosmetic procedures.
Explain the indications, complications, contraindications and method of application of
Botox, lasers, Fillers, micro -dermabrassion, Chemo- peels and Lasers.
Descibe the surgical cosmetic procedures of liposuction, face lift, Blepharoplasty, fat
grafting,abdomenoplasty.
Enumerate the indications, complications and contraindications of these surgical

procedures.
4) DPS Drm 16 CONGENITAL ABNORMALITIES

Enlist different kind of anomalies
Identify its time of reconstruction example Cleft lip/Palate, Hypospadias, Syndactly.
COMMUNITY MEDICINE
1) DPS Com 1 SCABIES
Define SCABIES
Explain its etiologic agent
Describe the epidemiology, control, and prevention of common skin diseases
2) DPS Com 2 FIREARM INJURIES
Describe and discuss the different patterns of

Fire Arm Injuries.
Explain how domestic injuries can be prevented
819
Dermatology/plastic surgery/burns Module:
IV. Introduction to basic surgical skills
ntroduction/Rationale
: Suturing is the most common method of wound closure, closing dead space, supporting and
strengthening wounds until healing increases their tensils strength, approximating skin edges
for an aesthetically pleasing and functional result, and minimizing the risks of bleeding and
infection.
Learning objectives
On completion of this module, students will be able to:
Demonstrate correct technique of handling of instruments

Demonstrate correct method of reef knot tying and suturing
DPS Sbl 2 SBL 2 :

Define the Tenia Capitis
Discuss the causes
Highlight the associated conditions
Discuss the management options
Explain the complications of the condition
DPS Sbl 4 SBL 4:

Describe a flap
Discuss the advantages of using the flap
classify the type of flap is Forehead flap
Discuss the complications of flap surgery
820
Total SUBJECT / ROUND
WEEKS/HOURS 1st 2nd
TOTAL X 40 OFF
2.5
ANATOMY 1 1.5 2.4 2
HISTOLOGY 1 - 1 0.9 1
HISTOLOGY 1.5
1.5 - 1.4 1
(Practical)
2
PHARMACOLOGY 2 - 1.9 2
PHYSIOLOGY 1 - 1 0.9
1
PATHOLOGY 2 2 4 3.9 4
PATHOLOGY 1.5
- 1.5 1.4 1
(Practical)
BIOCHEMISTRY 1.5 - 1.5 1.4 1
DERMATOLOGY 6 3 9 8.7 9
2
BURNS 2 - 1.9 2
PLASTIC SURGERY - 4 4 3.9 4

COMMUNITY Med 1 1.9 2
1 2
FORENSIC Med 1.5 - 1.5 1.5 2
SKILL LAB 1.5 - 1.5 1.5 2

SBL 3 3 6 5.8 6
TOTAL 25 16 41 39.2 40
821
GENETICS-2 MODULE
(SEMESTER-VIII)
THEORY

SEMESTE
R EXAM

Dermatology BCQs 34
Total 100
33
Phy Med Rehab BCQs
MODULE
EXAM

Dermatology BCQs 34
Total 100
STRUCTURED VIVA

SUMMATIV
ASSESME
SEMESTE
R EXAM
See Semester
NT

E
Assessment Plan
ASSESSMENT TOOLS
Structured Feedback
Facilitator
822
CREDIT HOURS
SEMESTER VIII
DERMATOLOGY and PLASTIC SURGERY-2 MODULE
Paper-II(iii) 1
DERMATOLOGY
and
PLASTIC SURGERY Paper IV B(iii) 0.5
823
GENETICS MODULE
Code: (GEN-2)
Semester: VIII
Fourth Year MBBS
824
Spiral Sem. Modules

II

4 Week
wks
Second th
Spiral th
Trauma, 6 week
3 week 8 Weeks
/ Burns 2 wk
2 Weeks
th
th
Third X
PARALLEL THEMES:
825
MODULE COMMITTEE
Prof .Dr. Khalid Mehmood, Professor of Medicine, DMC,CHK.
Prof .Dr. Naheed Khan , Professor of Ophthalmology, DMC.
Prof .Dr. Fouzia Imtiaz , Professor of Biochemistry, DMC.
Dr .Rukhsana Rubeen, Assistant Professor of Biochemistry, DMC.
Module Coordinator:
DR. SAIMA RASHID
Documented by:
DR SAIMA RASHID
Reviewed by:
Modular committee
826
RATIONALE:
Many of the diseases afflicting human beings have a genetic basis. The
molecular origin of these diseases is in the DNA of the patients and these are
often inherited from the parents and transmitted to the off springs. Many of
these diseases like hypertension and diabetes are multifactorial and are
discussed in other sections. In this module those disorders which have purely a
genetic basis and are frequently seen, have been discussed. This module also
revisits the molecular basis of genetics which has already been discussed in
detail in the previous modules.
TERMINAL OBJECTIVES
By the end of Medical Genetic module the students will be able
GENETICS
Discuss the structure of DNA,RNA ,transcription, translation and protein

synthesis
Describe the pathophysiology of inherited disorders
Recognize inborn errors of metabolism and single gene disorders,
multifactorial disorders
Explain the role of gene therapy and counseling in management of
genetic disorders
Describe the patho physiology, transfer and risk of genetic disorder
running in the population.
827
ATP
BCQS, SEQS EMQS
WRITTEN ASSESS
DIGITAL LIBRARY
SELF STUDY
TUTORIALS
PRACTICAL
LECTURES
SKILL LAB
LIBRARY
VIVA
SBL

t
Discuss the BIOCHEMISTRY GEN 2 Bio 1

DNA, RNA, * *
structure of DNA & TRANSCRIPTION,
RNA and their role TRANSLATION & PROTEIN 2
in protein SYNTHESIS
synthesis.
Identify the BIOCHEMISTRY GEN 2 Bio 2

Mode of transmission/ * *
pattern of
patterns of inheritance
inheritance of 1
characters in
population
Define the term * * *
Ploidy GEN 2 Pth 1
Pathophysiology of
Describe normal PATHOLOGY inheritance
Karyotype 1
Enlist different
types of
chromosomal
abnormalities
1.Identify the role * * *

of gene in GEN 2 Bio 3
production of BIOCHEMISTRY Single gene disorders 1
disease
2.Define Pedegree SCENARIO BASE

1.5 * * *
LEARNING
3. Justify the role GEN 2 Sbl 1
of gene & its DOWNS SYNDROME
interaction with
environment.
828
* * *
1
Enlist different GEN 2 Pth 2
inborn errors of Inborn errors of
PATHOLOGY metabolism
metabolism
Justify the role of

genes in causing
the inborn errors SCENARIO BASE * * *
1.5
LEARNING
GEN 2 Sbl 2
Familial
Hypercholesterolemia
Define
*
multifactorial
GEN 2 Bio 4 1
inheritance BIOCHEMISTRY Multifactorial disorders
Define polygenic
inheritance
Enlist common
diseases with
multifactorial
causes
Define * * *
GEN 2 Pth 3
Biotechnology 1
Genetic techniques
PATHOLOGY
Enlist its types
Discuss its
importance .
Explain different GEN 2 Bio 5

* * *
types of numerical BIOCHEMISTRY Cytogenetic
1
and structural Numerical and structural
abnormalities
abnormalities of SCENARIO BASE
chromosomes. LEARNING
GEN 2 Sbl 3
1.5 * * *
Thalassemia
829
Enlist the types of * * *
genetic testing GEN 2 Pth 4
PATHOLOGY Prenatal diagnosis
Identify genetic 1
disorders
1. Define Hardy GEN 2 Bio 6

* * *
Weinberg Law Population genetics
BIOCHEMISTRY
1
2. Explain the
factors which
shifted the law
from equilibrium
state
To provide 1 * * *
GEN 2 Med 1
information to Gene therapy &
patients (and/or MEDICINE councelling
blood relations of
a patient) at risk of
a disease that may
be hereditary .
Justify the role of BIOCHEMISTRY GEN 2 Bio7

1.5 * * *
TUTORIAL Genetic & Environmental
gens in disease
interaction of Disease
production
Enlist various types PATHOLOGY

GEN 2 Pth 5
Genetic mutations 1.5
* * *
TUTORIAL
of mutations
Justify their role in
disease causing
830
GENETICS MODULE
TIME TABLE
FIRST WEEK
Days 08:30 to 09:30 09:30 to 10:30 10:30 to 1:00 1:30 to 03:00
A1=Biochemistry Tutorial: Genetic & Environmental

interaction of Disease NAME OF FACULTY VENUE
A2= Pathology Tutorial: GENETIC Mutations
BIOCHEMISTRY REVISIT CLINICAL NAME OF FACULTY VENUE
1 DNA, RNA, Transcription, Translation & Protein synthesis
POSTING A3= CBL 1: Downs syndrome NAME OF FACULTY VENUE
NAME OF FACULTY
VENUE A4= CBL 2: Familial Hypercholesterolemia
A5= CBL 3:Thalessemia NAME OF FACULTY VENUE
A2=Biochemistry Tutorial: NAME OF FACULTY VENUE
A3= Pathology Tutorial: GENETIC Mutations
BIOCHEMISTRY NAME OF FACULTY VENUE
PATHOLOGY
Mode of Transmission/ Patterns
Pathophysiology of Inheritance CLINICAL A4= CBL 1: Downs syndrome NAME OF FACULTY VENUE
2 of Inheritance
NAME OF FACULTY A5= CBL 2: Familial Hypercholesterolemia
VENUE
VENUE NAME OF FACULTY VENUE
A1= CBL 3:Thalessemia NAME OF FACULTY VENUE
=Biochemistry Tutorial: NAME OF FACULTY
BIO LAB
= Pathology Tutorial: GENETIC Mutations
Genetic & Environmental interaction of Disease DR. DANISH
BIOCHEMISTRY PATHOLOGY NAME OF FACULTY
BIO LAB
Single gene disorders Inborn errors of metabolism CLINICAL NLH
3 CBL 1: Downs syndrome, NAME OF FACULTY VENUE
VENUE VENUE = CBL 2: F amilial Hypercholesterolemia
= CBL 3:Thalessemia NAME OF FACULTY VENUE
=Biochemistry Tutorial NAME OF FACULTY VENUE
= Pathology Tutorial: GENETIC Mutations

PATHOLOGY NAME OF FACULTY VENUE
BIOCHEMISTRY Genetic techniques CLINICAL
49 Multifactorial disorders NAME OF FACULTY POSTING CBL 1: Downs syndrome, NAME OF FACULTY VENUE
NAME OF FACULTY
VENUE VENUE
= CBL 2: F amilial Hypercholesterolemia
BIOCHEMISTRY PATHOLOGY
Cytogenetic Prenatal Diagnosis CLINICAL
5 Numerical and structural NAME OF FACULTY POSTING
abnormalities . NLH-1
NAME OF FACULTYNLH-
=Biochemistry Tutorial NAME OF FACULTYVENUE

CLINICAL FACULTY OF = Pathology Tutorial: GENETIC Mutations
MEDICINE NAME OF FACULTY VENUE
BIOCHEMISTRY Gene Therapy &Councelling CLINICAL CBL 1: Downs syndrome, NAME OF FACULTY VENUE
6 Population Genetics NAME OF FACULTY POSTING
NAME OF FACULTY CBL 2: F amilial Hypercholesterolemia
VENUE VENUE
831
LEARNING OBJECTIVES
BIOCHEMISTRY
1) GEN 2 Bio 1 DNA, RNA, TRANSCRIPTION, TRANSLATION & PROTEIN
SYNTHESIS
Define the terms gene,DNA, RNA

Describe transcription ,Translation
Discuss the structure of DNA & RNA and their role in protein synthesis.
2) GEN 2 Bio 2 MODE OF TRANSMISSION/ PATTERNS OF INHERITANCE

Enlist different mode of inheritance
Describe each type
Enlist the examples of each type
3) GEN 2 Bio 3 SINGLE GENE DISORDERS
Define pedigree
Identify symbols required to make pedigree
Define single gene disorders
Enlist different types of single gene disorders
Describe genetic changes which occur in these disorders
Enlist characteristics of single gene which gives variation in expression of
diseases
4) GEN 2 Bio 4 MULTIFACTORIAL DISORDERS
Define multifactorial inheritance

Define polygenic inheritance
Enlist common diseases with multifactorial causes
5) GEN 2 Bio 5 CYTOGENETIC NUMERICAL AND STRUCTURAL ABNORMALITIES
Give classification of genetic disorders

Describe different types of abnormalities based on the number and structure
of chromosomes
832
6) GEN 2 Bio 6 POPULATION GENETICS
Define Population genetics
Define genotype and allele frequency
Define Hardy- Weinberg equilibrium
Enlist the factors responsible for genetic variation in / among the population
Define genetic drift, genetic flow
PATHOLOGY
1) GEN 2 Pth 1 PATHOPHYSIOLOGY OF INHERITANCE
Define the term ploidy

Describe normal Karyotype
Enlist different types of chromosomal abnormalities
Enlist abnormalities related to chromosome structure
Justify the relation of chromosomal abnormalities and pregnancy
2) GEN 2 Pth 2 INBORN ERRORS OF METABOLISM
Justify the role of single gene in disease production

Enlist different inborn errors of metabolism
Describe one gene one enzyme concept
Justify the role of genes in causing the inborn errors.
3) GEN 2 Pth 3 GENETIC TECHNIQUES
Define Biotechnology
Discuss the importance of biotechnology in medical sciences
Define restriction endonucleases, sticky and blunt sites, vectors, plasmids,
probes, antibodies.
Describe restriction fragment length polymorphism and its significance.
Describe Polymerase chain reaction and its uses.
Describe recombinant DNA technology and its uses
4) GEN 2 Pth 4 PRENATAL DIAGNOSIS
Enlist the types of genetic testing

Identify genetic disorders in fetuses, newborns, and adults
Describe the Cells that are analyzed for heritable disorders
Explain that the Adults can be tested for many genetic disorders
Tests often done on large groups
some genetic conditions can be treated
Test results often create privacy issues
833
MEDICINE
1. GEN 2 Med 1 GENE THERAPY &COUNCELLING
To provide information to patients (and/or blood relations of a patient) at risk

of contracting a disease that may be hereditary on:
Consequence of pathology in question
Probability of contracting and transmitting it
Possibility of keeping it in check and treating it
1. GEN 2 Sbl 1 Sbl 1

Define the Downs Syndrome
Enlist the causes
Highlight the Organs/systems are involved in this condition
Explain investigations on basis of abnormal functioning of single part of a cell
Discuss the social issues are faced by the child & the parents
2. GEN 2 Sbl 1 Sbl 1
3. GEN 2 Sbl 3 Sbl 2 -

Define the Thalessemia.
Discuss the causes.
Enlist investigations
Discuss the pattern of illness
Explain the management of this disease
834
SUBJECT/15
WEEKS/HOURS 1st ROUND OFF
X 25
BIOCHEMISTRY 7
8.9 9
BIOCHEMISTRY
1.5 1.9 2
(tutorial)
5.1
PATHOLOGY 4 5
PATHOLOGY (tutorial) 1.5 1.5 2

1.2
MEDICINE 1 1
TOTAL FOR 2 SBL 4.5 5.7 6
TOTAL 19.5 24.5 25
835
GENETICS-2 MODULE
(SEMESTER-VIII)
THEORY

SEMESTE
R EXAM

Dermatology BCQs 34
Total 100
33
Phy Med Rehab BCQs
MODULE
EXAM

Dermatology BCQs 34
Total 100
STRUCTURED VIVA

SUMMATIV
ASSESME
SEMESTE
R EXAM
See Semester
NT

E
Assessment Plan
ASSESSMENT TOOLS
Structured Feedback
Facilitator
836
CREDIT HOURS
SEMESTER VIII
GENETICS -2 MODULE
Paper-II-(ii) 1
GENETICS-2
Paper-IV-B-(ii) 0.5
837
NEUROSCIENCES & PSYCHIATRY MODULE 02
CODE: NEU 2
SEMESTER-VIII
FOURTH (4TH) YEAR M.B; B.S
838
Spiral Sem. Modules

II

4 Week
wks
Second th
Spiral th
Trauma, 6 week
3 week 8 Weeks
/ Burns 2 wk
2 Weeks
th
th
Third X
PARALLEL THEMES:
839
MODULE COMMITTEE
PROF. DR SALAHUDDIN AFSAR, Professor of Medicine, DUHS
PROF. DR. JUNAID ASHRAF, Professor of Neurosurgery, DUHS
PROF. DR. RAZAUR-REHMAN, Professor of Psychiatry, DUHS
DR. NAILA NAEEM SHAHBAZ, Associate Professor of Neurology, DUHS
DR. NAHEED KHAN, Associate Professor of Anatomy, DUHS
DR. RUKHSANA RUBEEN ,Associate Professor of Biochemistry, DUHS

o Dr. Nighat Nisar, Professor of Community Medicine, DMC, DUHS
Module Documentation By:

DR. SABAHAT ZAIDI (Department of Anatomy , Dow Medical College ,DUHS)
DR.TANZEELA KHAN.(Department of Anatomy, Dow Medical College, DUHS)
Module Coordinated by:

DR. SAIMA RASHID (Department of Pathology , Dow Medical College ,DUHS)
Reviewed by:
MODULE COMMITTEE
840
RATIONALE
Nervous system is the most complex system of the body. Alarge number of diseases involve
the nervous system in their primary pathology or the nervous system may de secondarily
involved in systemic illnesses. Infections like meningitis and encephalitis, movement
disorders, demyelinating diseases, epilepsy and cerebrovascular accidents along with
congenital and traumatic disorders are some of the commoner diseases of the nervous system.
Timely diagnosis and management prevents high morbidity and mortality.
The Neurosciences 1 module in the basic cycle has already provided a sound basis of the
anatomy, physiology, neuropharmacology and pathologic basis of CNS diseases. In this
second, clinical spiral, the student will learn the clinical presentation, diagnosis and
management of these diseases.
TERMINAL OBJECTIVES
By the end of the 5 year curriculum the student shall be able to:
Recall functional neuro anatomy of brain and spinal cord
Revise embryology and histology of neuron ,nerve and neuroglia
Enlist the investigation for diagnosing neurological disorders
Discuss the assessment and management of raised ICP, cerebral edema and brain herniation
Differentiate between anxiety and depression, manic disorders and discuss their
management
Compare primary and secondary headache
Formulate a table to identify /classify drugs used for general ,regional and local anesthesia
Describe pathophysiology, clinical classification and management of seizure disorders
Know the approach for assessment and management of adult as well as paeds
stroke,dementia and Parkinson disease
Classify CNs infection and discuss the management
Explain pathology of degenerative disorders of brain
Recognize CP child and evaluation of mental retardation
Classify brain tumors and evaluate management plan for it
841
transfer, duration of teaching of content and the mode of assessment.
BCQS, SEQS EMQS

WRITTEN ASSESS;
DIGITAL LIBRARY
SELF STUDY
TUTORIALS
PRACTICAL
LECTURES
SKILL LAB
LIBRARY
VIVA
SBL

nt
ANATOMY NEU 2 Ana 1 1 * *

Functional Neuro
anatomy of Brain
Revisit the neuro
anatomy of brain
with its
development and
EMBRYOLOGY NEU 2 Ane 1 1 * *
Formulate the
REVISIT Development of
causes and
brain
consequences of
various birth
defects and
developmental
disorders NEUROSURGERY NEU 2 Neu Sur 1 1 * *
involving CNS Neural tube defects,
Forebrain
anomalies, Posterior
fossa anomalies
Revisit histology HISTOLOGY NEU 2 Anh 1 1 * *

of neurons and Neurons and
neuroglia Neuroglia
842
Predict the PATHOLOGY NEU 2 Pth 1 1 * *
reaction of Reaction of neurons
neurons and glial and glial cells to
cells to injury by injury , cerebral
knowing the hypoxia & cerebral
pathological edema
processes
affecting these
basic units of CNS.
NEUROLOGY NEU 2 Neu 1 1 * *
Investigations for
Neurological
Disorders
Investigations for
Neurological
RADIOLOGY NEU2 Rad1 CT Scan 1 * *
Disorders
brain
NEU2 Rad 2 MRI 1 * *

Brain
NEUROSURGERY NEU 2 Neu Sur 2 1 * *

Assessment of the
causes and
Predict the
general reaction management of
of brain to various cerebral edema,
injurious raised ICP,
processes in terms hydrocephalus and
of brain edema or brain herniations in
raised intracranial
all ages.
pressure and
develop a
RADIOLOGY NEU2 Rad 3 1 * *
management a
Radiological
plan.
appearance of head
injury and
hydrocephalus
PEDIATRICS NEU 2 Ped 1 1 * *
Causes of perinatal
Diagnose the
brain injury
causes and effects
of various
NEU 2 Ped 2 1 * *
perinatal brain
Cerebral Palsy &
injuries
Mental retardation
Describe the ANATOMY NEU 2 Ana 2 1 * *
clinical REVISIT Functional Neuro
presentation of anatomy of Spinal
brain and spinal Cord
cord trauma and
management
843
1. Skull fractures
2. Parenchymal
Injuries
Concussion
Direct
parenchyma
l injuries
Diffuse
axonal
injuries
3. Traumatic
vascular injuries
Epidural/su
dural
hematoma
4. Sequelae of
brain trauma
Changes in level of
consciousness and
approach to coma
Spinal cord trauma
PHARMACOLOGY NEU 2 Pha 1 1 * *

Sedative and
Hypnotics

REVISIT Anatomy of
Manage ischemic circulation of brain:
or hemorrhagic Anterior and
cerebrovascular posterior cerebral
events by knowing circulation
their effect on
brain parenchyma NEUROLOGY NEU 2 Neu 3 1 * *
and the various Clinical Feature and
clinical effects Diagnosis of
thus cerebrovascular
produced.along accidents
with radiological
NEU 2 Neu 4 1 * *
diagnosis and
Approach to and
introduction to
management of
neuro
stroke
rehabilitation and
rehabilitation of PEDIATRICS NEU 2 Ped 3 1 * *
patient Approach to and
management of
844
stroke in children

Intracranial
hemorrhage
RADIOLOGY NEU2 Rad 4 Neuro 1 * *

radiology of stroke
and cerebral
angiography +
interventional
radiology
COMMUNITY NEU 2 Com 1 1 * *
MEDICINE Risk factors causing
stroke & their
prevalence in
community
REHABLITATION NEU 2 PMR 1 1 * *

Introduction to
neuro rehabilitation
NEU 2 PMR 2 1 * *
Rehablitation of
stroke patient
MICROBIOLOGY NEU 2 Mic 1 1 * *

REVISIT Common pathogens
of nervous system
with special
Correlate reference to
between clinical different age
presentations and groups.
pathogenic
mechanisms NEUROLOGY NEU 2 Neu 5 1 * *
involved in CNS Clinical features of
infections and meningitis,
infestations. encephalitis and
brain abscess in
adults and children.
CNS Infections:
Acute and Chronic 1
845
NEU 2 Neu 6 1 * *
Complications of
meningitis/
encephalitis in
adults and children
patients.CNS
Infections: Acute
and Chronic 2
PATHOLOGY NEU 2 Pth 2 1 * *

Degenerative
diseases of cerebral
cortex like
Alzheimers Disease
NEU 2 Pth 3 1 * *
Degenerative
diseases of basal
ganglia
(Parkinsonism) &
brainstem

Identify the Drugs for
involvement of parkinsoism
isolated or
multiple brain NEUROLOGY NEU 2 Neu 7 1 * *
Approach to
regions and
movement
structures in
disorders D/d of
degenerative
involuntary
disorders and
movements.
know resulting
clinical
NEU 2 Neu 8 1 * *
syndromes. Approach to
Dementia
PAEDS NEU 2 Ped 4 1 * *

Leukodystrophies,
Wilsons Disease,
SSPE,
Develop an BIOCHEMISTRY NEU 2 Bio 1 1 * *

REVISIT Role of vitamins in
approach to
normal functioning
manage acquired
of nervous system
toxic and
846
metabolic PAEDS NEU 2 Ped 5 1 * *
disorders affecting Approach To
brain. Metabolic & Toxic
Disorders Affecting
Nervous System In
Children

Brain tumors I
Relate the NEU 2 Pth 5 1 * *

Brain tumors II
neoplastic
processes
involving different NEUROSURGERY NEU 2 Neu Sur 6 1 * *
parts of brain with Approach &
their clinical Management of CNS
presentations at tumors at different
different ages. ages

Radilogical
appearance of brain
tumor
NEU 2 Neu 9 1 * *
Difference between
upper & lower
motor neuron
lesions
NEU 2 Neu 10 1 * *
Localize the lesion Usual features of
to spinal cord and NEUROLOGY intrinsic and
differentiate extrinsic spinal cord
between lesions
pathogenic
mechanisms NEU 2 Neu 11 1 * *
involved. Compressive & non
compressive
myelopathies
NEU 2 Neu 12 1 * *
Differentiate b/w
rigidity and
spasticity.
847
NEU 2 Neu 13 1 * *
Approach towards
paraparesis
Diseases of the
Describe peripheral nerves
pathology of
different types of NEUROLOGY NEU 2 Neu 14 1 * *
neuropathies and Clinical approach to
their etiologies neuropathy
like metabolic,
inflammatory, etc. NEU 2 Neu 15 1 * *
D/d of neuropathies
Clinical types of
neuropathies GBS
Diseases of skeletal
muscles
Traumatic
myelopathies

Clinical approach to
myopathies
BIOCHEMISTRY NEU 2 Bio 2 1 * *

Describe inborn Metabolic
REVISIT
errors of myopathies
metabolism and associated with
associated
neuromuscular Glycogen
disorders. Lipid
mitochondri
al
Congenital &
metabolic
myopathies
NEU 2 Neu 18 1 * *
Clinical features, d/d
and investigations
of myasthenia
848
gravis.
REHABLITATION NEU 2 PMR 3 1 * *

Rehablitation in
chronic
myelopathies
Differentiate NEUROLOGY NEU 2 Neu 19 1 * *
between different Motor neuron
types of anterior disease
horn cell disorders
know their NEU 2 Neu 20 1 * *
SMA
pathology, clinical
features and
investigations. NEU 2 Neu 21 1 * *
Poliomyelitis

Clinical classification
of seizure disorders
NEU 2 Neu 23 1 * *
Taking history in
patients with
Manage different
epilepsy, ordering
types of seizure
investigations and
disorders by
plan management
knowing their
pathophysiologic PHARMACOLOGY NEU 2 Pha 3 1 * *
basis and clinical Anti epileptic drugs
types including
management of
status epilepticus
Approach to seizure
disorders in
children(epilepsy)

Management of
status epilepticus

Localize the
Cerebellum
cerebellum and (revisit) NEU 2 Ana 5 1 * *
cranial nerves Cranial nerves
849
lesions and their (revisit)
radiological
appearance NEUROLOGY NEU 2 Neu 25 1 * *
Lesions of cranial
nerves
Radiological
features of normal
and diseased spine
and vertebral
column
ANESTHESIA NEU 2 1 * *
Pre operative
assessment of
patient for GA
General anesthesia 1 * *
Application of
anesthesia in case Regional anesthesia 1 * *
of neurological
disorders
Drugs of general
anesthesia
NEU 2 Pha 5 1 * *
Drugs of local
anesthesia
PSYCHIATRY NEU 2 Beh 1 1 * *

Anxiety disorders
NEU 2 Beh 2 1 * *
Manage anxiety Depressive
and depression disorders
when it begins to
interfere with PHARMACOLOGY NEU 2 Pha 6 1 * *
social or Drugs for migraine
occupational
functioning. NEU 2 Pha 7 1 * *
Anti psychotic drugs
NEU 2 Pha 8 1 * *
Anti depressents

Approach and
Drug /alcohol
manage
dependence
addiction
850
CNS stimulants and
hallucinogens
COMMUNITY Neu 2 Com 2 1 * *

MEDICINE Public health
principles and
neurological
Recognize the disorders
importance of
Community Neu 2 Com 3 1 * *
medicine in Global burden of
neurological neurological
disorders disorders

Behavioral
disorders
NEU 2 Beh 5 1 * *
Suicide and self
harm
Manage NEU 2 Beh 6 1 * *

Schizophrenic
behavior
disorders
disorders in
adult as well as NEU 2 Beh 7 1 * *
children Medically
unexplained
symptoms

Neuro psychotic
and behavior
disorders in
children
851
NEUROSCIENCES-2 MODULE
TIME TABLE
FIRST WEEK
Days 08:30 to 09:30 09:30 to 10:30 10:30 to 1:00 1:30 to 03:00

1=A1=Skill lab= Lumbar
Puncture A2=self study
Anatomy revisit
1 2=B=CBL VENUE
Functional Neuro anatomy of Brain
CLINICAL POSTING 3=C=CBL VENUE
NAME OF FACULTY
VENUE 4=D= VENUE
5=E= VENUE
Pathology
Anatomy Reaction of neurons and 1=B1,B2
Histology revisit Neurons and glial cells to injury , 2=C
2 Neuroglia cerebral hypoxia & CLINICAL POSTING 3=D
NAME OF FACULTY cerebral edema 4=E
VENUE NAME OF FACULTY 5=A
VENUE
Neurosurgery
1=C1, C2
Anatomy Congenital disorders of
2=D
3 Embryology revisit CNS: Neural tube
CLINICAL POSTING 3=E
Development of brain defects
4=A
VENUE VENUE 5=B
Neurosurgery Neurology
Synthesis and flow of CSF 1=D1, D2
4 along with its composition. Investigations for 2=E
Hydrocephalus & its Neurological Disorders CLINICAL POSTING 3=A
Management NAME OF FACULTY 4=B
NAME OF FACULTY VENUE 5=C
VENUE
Neurosurgery Radiology
Raised intracranial and its
5 effects: management of cerebral CT Scan Brain
edema, raised ICP, and brain CLINICAL POSTING
herniations NAME OF FACULTY
VENUE
Pharmacology 1=E1, E2
Psychiatry
Sedatives & hypnotics: 2=A
6 Anxiety disorders
Benzodiazepines CLINICAL POSTING 3=B
NAME OF FACULTY
VENUE
NAME OF FACULTY 4=C
VENUE 5=D
852
Semester VIII, Week-2
Days 08:30 to 09:30 09:30 to 10:30 11:00 to 1:00 1:30 to 03:00

Clinical Neurology Anesthesia
Primary headache Pre operative
1 syndromes Assessment of patient CLINICAL
Self study.
for GA POSTING
NAME OF FACULTY
VENUE NAME OF FACULTY
VENUE
2
EID HOLIDAY
3
EID HOLIDAY
4 EID HOLIDAY
5 EID HOLIDAY
Clinical Neurology
Pharmacology Secondary headache
Sedatives & syndromes& Psychiatry
6 hypnotics: Trigeminal CLINICAL NAME OF
Barbiturates associated Cranial POSTING FACULTY
and facial neuralgias VENUE
NAME OF FACULTY
VENUE
NAME OF FACULTY
VENUE
853
Semester VIII, Week- 3
Days 08:30 to 09:30 09:30 to 10:30 10:30 to 1:00 1:30 to 03:00

A1=Self Study
A2=Skill lab
Clinical Anesthesia Pharmacology B=CBL NAME OF
FACULTY
General Anesthesia CLINICAL VENUE
1 NAME OF FACULTY Drugs for Migraine Rx
. POSTING C=CBL= NAME OF
VENUE
VENUE VENUE
D=Digital library
Pharmacology 1=B1= Self Study,

Anesthesia B2= Skill lab
Drugs of Anesthesia: CLINICAL
2 Regional Anesthesia 2=C
General anesthetics 1 NAME OF FACULTY POSTING
NAME OF FACULTY
VENUE 3=D
VENUE 4=A
Pharmacology 1=C1= Self Study,

Neurosurgery
Drugs of Anesthesia: C2= Skill lab
Traumatic Brain injury CLINICAL
General anesthetics 2=D
I POSTING
3 2 NAME OF FACULTY 3=A
NAME OF FACULTY
VENUE 4=B
VENUE
1=D1= Self Study,

Pharmacology D2= Skill lab
Local anesthetics CLINICAL
SELF-STUDY POSTING 2=A
4 NAME OF FACULTY
3=B
VENUE
4=C
Neurology
Rehabilitation
Changes in level of
Introduction to Neuro CLINICAL
5 consciousness and
rehabilitation POSTING
approach to Coma NAME OF FACULTY
NAME OF FACULTY
VENUE
VENUE
Neurology
Pathophysiology and PEDIATRIC
Clinical classification Childhood epileptic CLINICAL
6 & Management of Symdromes SELF-STUDY
POSTING
seizure disorders NAME OF FACULTY
VENUE
854
Semester VIII, Week-4
Days 08:30 to 09:30 09:30 to 10:30 10:30 to 1:00 1:30 to 03:00

Neurology A=CBL Neurosurgery
Pharmacology
1 Antidepressents Management of status B=CBL Psychiatry
epilepticus CLINICAL POSTING C=Skill Lab
NAME OF FACULTY
NAME OF FACULTY
VENUE VENUE D=Digital library
Neurology
Introduction to & Uses
of Pharmacology
2 Electroencephalograph Anti epileptic drugs
y (EEG) CLINICAL POSTING
NAME OF FACULTY
VENUE
NAME OF FACULTY
VENUE
Psychiatry Pharmacology
Mania and Psychotic Antipsychotic Drugs CLINICAL POSTING

3
Disorders NAME OF FACULTY
VENUE
Anatomy
Neurology
Anatomy of
circulation of brain: Clinical Feature and
Anterior and posterior Diagnosis of CLINICAL POSTING
4 cerebral circulation cerebrovascular
accidents
NAME OF FACULTY
NAME OF FACULTY
VENUE VENUE
Radiology Neurology
5 MRI Brain Approach to and

NAME OF FACULTY management of stroke CLINICAL POSTING
VENUE
NAME OF FACULTY
VENUE
Pediatrics Neurosurgery
Approach to Pediatric
6 Stroke Intracranial Hemorrhage CLINICAL POSTING Research Presentation
VENUE VENUE
855
NEUROSCIENCES-2, SEMESTER-8
WEEK-5 TIME TABLE
Days 08:30 to 09:30 09:30 to 10:30 10:30 to 1:00 1:30 to 03:00

1 A1=Digital library
RADIOLOGY A2=SELF STUDY
PHARMACOLOGY 2 A3=CBL: Neurology= NAME OF
Brain tumors,head injury CLINICAL
1 CNS stimulants FACULTY
and hydrocephalus NAME OF FACULTY POSTING VENUE
NAME OF FACULTY
VENUE 3 A4= SELF STUDY
VENUE
4 A5=Digital library
Neurology PSYCHIATRY 1. A2
Approach to and Medically Unexplained CLINICAL 2. A3
2 Management of Dementia symptoms Radiology POSTING 3. A4
VENUE VENUE 4. A5+A1
Community Medicine
Public awareness 1. A3
regarding neurological CLINICAL 2. A4
3 SELF STUDY disorders POSTING
NAME OF FACULTY
3. A5+A1
VENUE
4. A2
Neurology
Approach to movement RESEARCH
PSYCHIATRY CLINICAL
4 disorders Analysis of variants
Somatoform disorders POSTING NAME OF FACULTY
NAME OF FACULTY
Parkinsons disease
VENUE
VENUE
Pharmacology CLINICAL
5 SELF STUDY Drugs for Parkinsonism POSTING
NAME OF FACULTY
VENUE
Pediatrics
Cerebral Palsy 1. A4
Mental retardation CLINICAL 2. A5+A1
6 SELF STUDY POSTING
VENUE 4. A43
856
NEUROSCIENCES 2, SEMESTER 8
TIME TABLE WEEK-6
10:45 to
Days 08:30 to 09:30 09:30 to 10:30 1:30 to 03:00
12:45
1.A1= CBL :Neurosurgery
NAME OF FACULTY
VENUE
ANATOMY HISTO
PATHOLOGY 2.A2= CBL: Neurology
Revisit CLINICAL
1 Brain tumors I NAME OF FACULTY
NAME OF FACULTY Cerebellar cortex POSTING VENUE
VENUE 3.A3= DIGITAL LIBRARY
4.A4=SELF STUDY
5.A5= SELF STUDY
PATHOLOGY PSYCHIATRY 1. A2
Brain tumors II Suicide and Self harm CLINICAL 2. A3
2
NAME OF FACULTY NAME OF FACULTY POSTING 3. A4
VENUE VENUE 4. A1+A5
NEUROLOGY
Demyelinating disorders 1. A3
CLINICAL 2. A4
3 of CNS SELF STUDY POSTING
NAME OF FACULTY 3. A1+A5
VENUE 4. A2
COMMUNITY
NEUROSURGERY RESEARCH
MEDICINE
Approach & CLINICAL
4 Neurological disorders: A PRESENTATION
Management of CNS POSTING
public health approach NAME OF FACULTY
NAME OF FACULTY
tumors VENUE
VENUE
NEUROLOGY
PSYCHIATRY
Clinical approach to CLINICAL
5 Behavioral disorders
Ataxias NAME OF FACULTY POSTING
VENUE
PEDIATRICS
Neuropsychotic 1. A4
Behavior disorders in CLINICAL 2. A1+A5
6 SELF STUDY
Children POSTING 3. A2
VENUE
857
NEUROSCIENCES 2, SEMESTER 8
TIME TABLE WEEK-7th
10:45 to
Days 08:30 to 09:30 09:30 to 10:30 1:30 to 03:00
12:45
2 PUBLIC HOLIDAY
ANATOMY revisit NEUROLOGY

CLINICAL
4 Cranial nerves Lesions of cranial nerves
POSTING NAME OF FACULTY
NAME OF FACULTY
VENUE VENUE
ANATOMY REVISIT
Functional Neuroanatomy of Spinal Cord CLINICAL
5
VENUE
CLINICAL
NEUROLOGY
NEUROSURGERY
RADIOLOGY
Non compressive Radiological features of Normal
Compressive CLINICAL
6 myelopathies and Diseased Spine & Vertebral
Myelopathies POSTING
clinical features and NAME OF FACULTY Column
management VENUE NAME OF FACULTY
VENUE
858
NEUROSCIENCES-2 SEM-8,
TIME TABLE WEEK-8
10:30 to 1:00 1:30 to 03:00

Days 08:30 to 09:30 09:30 to 10:30
Neurology
Psychiatry Depression Disorders of Anterior Neurology
1 Disorders Horn Cells CLINICAL Mysthenia Gravis
VENUE POSTING VENUE
VENUE
Neurology Neurology
Psychiatry
Classification & Clinical Clinical approach to
Schizophrenic CLINICAL
2 approach to myopathies:
Disorders POSTING neuropathy & GBS
Ducchenne muscular NAME OF FACULTY NAME OF FACULTY
VENUE
CLINICAL
3
SELF STUDY POSTING SELF STUDY
CLINICAL
4 SELF STUDY POSTING
5 MODULE TEST
859
LEARNING OBJECTIVES
ANATOMY
1. NEU 2 Ana 1 (REVISIT) Functional Neuro anatomy of Brain
Recall the anatomy of the brain
Describe different parts of the brain
Discuss openings found in the skull
Recognize brain structures on the bases of their anatomical relations
2. NEU 2 Ana 2 (REVISIT) Functional Neuro anatomy of Spinal Cord
Recall the knowledge of spinal cord
Discuss the nuclei of spinal cord
Discuss the ascending and descending tracts of spinal cord
3. NEU 2 Ana 3 (REVISIT) Circulation of brain: anterior and posterior cerebral circulation
Arterial supply of the brain

Division of the arterial system into Carotid & Vertebral Systems
Branches of Internal carotid & Vertebral arteries.
Different areas of brain supplied by different branches of these arterial systems &
blood supply of areas other than cerebral cortex
Applied aspects related to the blockage & Hemorrhage of blood vessels supplying
brain
4. NEU 2 Ana 4 (REVISIT) Cerebellum
Describe anatomical position of cerebellum

Functional abilities of cerebellum
Describe pathologies related to cerebellum
Elaborate investigation plans to evaluate cerebellar diseases
860
5. NEU 2 Ana 5 (REVISIT) Cranial nerves
Describe anatomical position of cranial nerves

Classify cranial nerves
Functional abilities of cranial nerves
Describe pathologies related to cranial nerves
Elaborate investigation plans to evaluate cranial nerves diseases
EMBRYOLOGY
1. NEU 2 Ane 1 (REVISIT) Development of brain
The origins of nervous system

Primary and secondary brain vesicles
Development of spinal cord
Development of brain stem
Development of cerebral hemispheres
HISTOLOGY
1. NEU 2 Anh 1 (REVISIT) Neurons and Neuroglia
Recall the previous knowledge of the nerve cells

Discuss the types of neurons
Describe the parts of neurons
Recall the supporting cell of nervous system, their type and functions
NEUROSURGERY
1. NEU 2 Neu Sur 1 Congenital Anomalies of CNS:
Describe various kinds of congenital CNS disorders

Explain the embryology of these disorders
Discuss their clinical presentations & radiological findings
Describe their management / treatment methods
861
2. NEU 2 Neu Sur 2 Synthesis And Flow Of Csf Along With Its Composition.
Hydrocephalus & Its Management
Define CSF and its composition

Describe the formation and circulation of CSF
Identify different pathologies by the help of radiological investigations
Describe Hydrocephalus its signs and symptoms and management plan.
3. NEU 2 Neu Sur 3 Traumatic Brain Injury I & II

Define brain injury
Enlist the causes of brain injury
Explain the biomechanics of injury
Classify the head injury.
Assess & manage the traumatic brain injury patients
4. NEU 2 Neu Sur 4 Spinal Cord Trauma
Define spnial cord injury

Enlist the causes of injury
Explain the biomechanics of injury
Classify the injury.
Assess & manage the traumatic spinal cord injury patients
5. NEU 2 Neu Sur 5 Intracranial Hemorrhage
Define intracranial hemorrhage

Differentiate between traumatic and non traumatic hemorrhage
Classify the types of intracranial hemorrhage
Discuss the pathophysiology of intracranial hemorrhage
Elaborate the differential diagnosis
Discuss the management plan of intracranial hemorrhage
6. NEU 2 Neu Sur 6 Approach & Management Of CNS Tumors At Different Ages
Basic approach towards any CNS tumors

Protocols to be followed in the management of CNS tumors
Investigation criteria for CNS tumors
Stepwise treatment plan for CNS tumors
7. NEU 2 Neu Sur 7 Traumatic Myelopathies
Define traumatic myelopathies

Explain mechanism of injury
Classify traumatic myelopathies on the basis of physical damage to cord and
pathological response.
Enlist the treatment plan
862
PATHOLOGY
1. NEU 2 Pth 1 Reaction Of Neurons And Glial Cells To Injury , Cerebral Hypoxia &
Cerebral Edema
Discuss the pathological changes seen in neurons and glial cells due to different
pathological stress
Classify neuronal injuries ,causes and pathophysiology
Describe cerebral hypoxia, causes and pathogenesis
Elaborate cerebral edema and its pathogenesis
2. NEU 2 Pth 2 Degenerative Diseases Of Cerebral Cortex Like Alzheimers Disease
Define and classify degenerative cortical diseases.

Describe pathophysiology of different degenerative disorders.
Identify signs of symptoms of the given pathologies.
Elaborate management plan for the given pathologies.
3. NEU 2 Pth 3 Degenerative Diseases Of Basal Ganglia (Parkinsonism) & Brainstem
Define and classify degenerative diseases of basal ganglia and brain stems
Describe pathophysiology of different degenerative disorders.
Identify signs of symptoms of the given pathologies.
Elaborate management plan for the given pathologies.
4. NEU 2 Pth 4 Brain Tumors
Define benign and malignant intracranial tumors

Describe histopathologies of brain tumors
Explain clinical effects of raised intracranial pressures
5. NEU 2 Pth 5 Brain Tumors II
Define benign and malignant intracranial tumors

Describe histopathologies of brain tumors
Explain clinical effects of raised intracranial pressures
6. NEU 2 Pth 7 Diseases Of Skeletal Muscles
Describe the normal histological presentation of a skeletal muscle

Classify diseases related to skeletal muscle
Recognize the pathophysiological pattern for skeletal muscle pathologies
Management plan for various muscle pathologies.
863
PHARMACOLOGY
1. NEU 2 Pha 1 Sedative And Hypnotics
Define sdative and hypnotics

Classify the drugs
Discuss their mechanism of action
Enlist the therapeutic uses of the drugs.
2. NEU 2 Pha 2 Drugs For Parkinsonism
Explain the extrapyramidal tract for Parkinson disease

Understand the treatment options of parkinsons disease
Discuss their pharmacokinetics and adverse effects
3. NEU 2 Pha 3 Anti Epileptic Drugs
Define epilepsy and seizures

Tell the difference between epilepsy and seizures
Discuss the etiology of epilepsy
Elaborate the types of epilepsy
Classification of anti epileptic drugs
Discuss the side effects of anti epileptic drugs
Identify the Possible mechanism of action of anti-epileptics
4. NEU 2 Pha 4 Drugs Of General Anesthesia
Describe stages of general anesthesia and the anesthetic agents used

Define the mode of action of different general anesthetics
Recognize complications related to different agents.
5. NEU 2 Pha 6 Drugs For Migraine
Define migraine
Classify Migraine
Identify different treatment options for the given pathology
Pharmacokinetics and dynamics
Side effects of given therapeutics
6. NEU 2 Pha 7 Anti Psychotic Drugs
After completion of the lecture the student should be able to
864
List three different classes of antipsychotic drugs and describe the main
pharmacological effects they produce
Describe the common adverse effects and specific neurological conditions caused by
antipsychotic drugs
Explain the mechanism of action and uses of antipsychotic drugs
List the adverse effects associated with antipsychotic drugs.
Describe the pharmacology of drugs used to treat some forms of mental illness.
Explains how antipsychotic drugs suppress the symptoms of schizophrenic and other
psychotic conditions, and explains the numerous adverse effects that these drugs
produce.
7. NEU 2 Pha 8 Anti Depressents
Classification of anti depressants

Discuss the signs and symptoms of depression
Enlist the differential diagnosis
Discuss the possible Causes of this disorder
Describe the management options and treatment
8. NEU 2 Pha 9 CNS Stimulants And Hallucinogens
List different classes of drugs CNS stimulants:

Describe the main pharmacological effects they produce
Describe the common side effects
Explain the mechanism of action and uses of CNS stimulants drugs.
PSYCHIATRY
1. NEU 2 Beh 1 Anxiety Disorders
Define Anxiety and related disorders

Describe Phobic disorders and there presentation
Describe Panic disorder and there presentation
Describe OCD and its presentation
2. NEU 2 Beh 2 Depressive Disorders
Describe Mood Disorders

Elaborate its epidemiology
Understand the etiology of Depression
Explain the treatment of Major Depression
3. NEU 2 Beh 3 Drug /Alcohol Dependence
Define addiction and its types

Classify addiction on the bases of the agents
865
Describe categories of psychoactive drugs
Elaborate the effects of alcohol on body
Identify different types of dependences
4. NEU 2 Beh 4 Behavioral Disorders
General characteristics of Behavioral Disorders

Types of Behavioral Disorders
Describe Oppositional Defiant Disorderits types ,causes and management plan
Describe Conduct Disorderits types ,causes and management plan
Describe Attention Deficit Hyperactivity Disorder (ADHD),its types ,causes and
management plan
5. NEU 2 Beh 5 Suicide And Self Harm
Recognize Patterns and Statistics

Identify triggers of suicide
Describe common predictors of suicide
Elaborate management plan for given pathologies
6. NEU 2 Beh 7 Medically Unexplained Symptoms
Describe Medically unexplained symptoms

List different types of MUS
Investigations to roll out MUS
Treatment plans for MUS
Schizophrenic Disorders
7. NEU 2 Beh 6 Schizophrenic Disorders

Define Schizophrenia
Pathophysiology of the given disorders
Classify schizophrenic disorders
Investigation modularity
Management plan of the given pathology
COMMUNITY MEDICINE
1. NEU 2 Com 1 Risk Factors Causing Stroke & Their Prevalence In Community
Identify risk factor causing stroke

Prevalence and causes of stroke
Classify stroke
Describe management plan of stroke
866
2. Neu 2 Com 2 Public Health Principles And Neurological Disorders
Identify neurological disorders

Describe pathophysiology of neurological disorders
Recognize causes and burden of neurological disorders
Management protocol for emergency neurological disorders
3. Neu 2 Com 3 Global Burden Of Neurological Disorders
Describe neurological disorder with its pathophysiology

Recognize its general assessment findings
Explain the burden of neurological disorders in percentage
Elaborate the causes of neurological disorders
REHABILITATION
1. NEU 2 PMR 1 Introduction To Neuro Rehabilitation
Explain neuro rehablitation

Describe the implementation of neuro rehblitation in our daily life
2. NEU 2 PMR 2 Rehablitation Of Stroke Patient
Classify stroke
Describe pathophysiology of stroke
Identify therapeutic and surgical interventions of stroke
Elaborate investigation criteria for stroke
3. NEU 2 PMR 3 Rehablitation In Chronic Myelopathies
Classify SCI
Describe Asia impairment scale
Therapeutic interventions
Surgical interventions
NEUROLOGY
1. NEU 2 Neu 1 Investigations for Neurological Disorders
Describe neurological disorders

Identify investigation techniques used to roll out neurological disorders
Complications related to the respective investigative techniques
867
2. NEU 2 Neu 2 Changes In Level Of Consciousness And Approach To Coma
Describe the term coma

Define ALOC
Elaborate GCS scoring
Management plans for Comatose patients
3. NEU 2 Neu 3 Clinical Feature And Diagnosis Of Cerebrovascular Diseases
Define stroke ,TIA, Stroke-in-evolution,completed stroke

Discuss the pathophysiology of complete stroke
Describe the clinical presentations of stroke
Elaborate the five major stroke syndromes2for rapid recognition in the ER
Enumerate the investigations for the diagnosis of stroke
4. NEU 2 Neu 4 Approach To And Management Of Stroke
After completion of the lecture the student should be able to

Discuss the epidemiology and risk factors of cerebro-vascular disease & stroke
Discuss the different types of brain hemorrhage
Elaborate the treatment modalities of cerebral infarction
Describe the role of rehabilitation in stroke
Differentiate between intracerebral hemorrhage and thromboembolic infarction
clinically
5. NEU 2 Neu 5 Clinical Features Of Meningitis, Encephalitis And Brain Abscess In Adults
And Children. CNS Infections: Acute And Chronic 1
Classify meningitis on the bases of the causative organism

Describe the mode of transmission
Differentiate between meningitis and encephalitis
Radiological analysis of the given pathologies.
6. NEU 2 Neu 6 Complications Of Meningitis/ Encephalitis In Adults And Children

Patients.CNS Infections: Acute And Chronic 2
Describe meningitis and its types.

Identify different types of meningitis on the bases of its symptoms and signs.
Elaborate test performed to confirm the diagnosis.
Explain the management plan for different types of meningitis.
868
7. NEU 2 Neu 7 Approach To Movement Disorders D/D Of Involuntary Movements.
Define invluntry movements

Classify them on the basis of lesion
Discuss differential diagnosis of involuntary movement
Enlist the management plans
8. NEU 2 Neu 8 Approach To Dementia
Explain dementia
Approach a patient with dementia
Evaluate its laboratory findings
Understand its prevention and management
9. NEU 2 Neu 9 Difference Between Upper & Lower Motor Neuron Lesions
Recognize anatomy upper and lower motor neuron

Describe Lesions related to upper and lower motor neurons
Differentiate between UMN and LMN lesions
10. NEU 2 Neu 10 Usual Features Of Intrinsic And Extrinsic Spinal Cord Lesions
Recognize anatomy intrinsic and extrinsic spinal cord lesions.

Describe intrinsic and extrinsic spinal cord lesions pathophysiology.
Differentiate between intrinsic and extrinsic spinal cord lesions.
Identify clinical features of intrinsic and extrinsic spinal cord lesions.
11. NEU 2 Neu 11 Compressive & Non Compressive Myelopathies

Classify compressive myelopathy
Identify the causes of compressive myelopathy
Describe pathophysiology of different compressive myelopathies
Establish management plans for the given pathology
Define terms myelopathy and myelitis
Mention the possible etiology
Describe spinal cord syndromes and their clinical aspects
Evaluate the diagnostic tools and treatment options for the respective diseases
12. NEU 2 Neu 12 Differentiate B/W Rigidity And Spasity
Define rigidity and spasticity

Identify pathologies related to rigidity and spasticity
Recognize and differentiate rigidity and spasticity on the bases of clinical presentation
Set a management plans for the given pathologies
869
13. NEU 2 Neu 13 Approach Towards Paraparesis
Define paresis and classify them

Describe pathophysiology of paraparesis
Elaborate clinical features of the given pathologies
Set parameters for investigation and management options
14. NEU 2 Neu 14 Clinical Approach To Neuropathy

Define neuropathy and its types
Recognize its clinical features
understand its investigations and assess its findings
Construct the management plans for the given disease
15. NEU 2 Neu 15 D/D Of Neuropathies Clinical Types Of Neuropathies GBS
Describe neuropathies and classify them

D/D of neuropathies
Clinical features and types of neuropathies
Pathophysiology of GBS
Investigative and treatment plans for GBS
16. NEU 2 Neu 16 Clinical Approach To Myopathies
Classification of Myopathies
Identify different types of myopathies on the bases of history and examination
Describe the pathophysiology of common myopathies
Elaborate treatment plan for the given pathologies
17. NEU 2 Neu 17 Congenital & Metabolic Myopathies
Describe congenital and metabolic myopathies

Enlist types of congenital and metabolic myopathies
Elaborate pathophysiology and clinical features
Identify myopathies through various investigations
Set a management plan for the given pathologies
18. NEU 2 Neu 18 Clinical Features, D/D And Investigations Of Myasthenia Gravis.
Describe epidemiology of myasthenia gravis

Elaborate pathophysiology of myasthenia gravis
Describe clinical features of the given pathologies
Identify investigations related to myasthenia gravis
Establish management plans for the given pathology
870
19. NEU 2 Neu 19 Motor Neuron Disease
Describe anatomy of motor neurons

Classify motor neuron diseases
Identify moto neuron disease on the bases of clinical features and investigations
Set a treatment plan for the given pathologies
20. NEU 2 Neu 20 SMA
Describe SMA
Classify SMA
Describe pathophysiology related to SMA
Identify SMA on the bases of clinical features and investigations
21. NEU 2 Neu 21 Poliomyelitis
Describe Poliomyelitis
Elaborate etiology of poliomyelitis
Describe pathophysiology related to Poliomyelitis
Identify poliomyelitis on the bases of clinical features and investigations
22. NEU 2 Neu 22 Clinical Classification Of Seizure Disorder
Define seizures
Classify seizures
Clinical features of seizures
Identify Causes and risk factors
Describe Pathophysiology and clinical classification
Elaborate Management plans
23. NEU 2 Neu 23 Taking History In Patients With Epilepsy, Ordering Investigations And
Plan Management
Describe epilepsy and its salient features

Evaluate important aspects of the description given by the patient suffering from
epilepsy
Understand the need of investigations to assess the disease
State the plan of management for such patients
24. NEU 2 Neu 24 Management Of Status Epilepticus
Recognize a patient of status epilepticus

Describe its clinical features
Evaluate the investigations of status epilepticus
Understand the treatment of status epilepticus.
871
25. NEU 2 Neu 25 Lesions Of Cranial Nerves
Describe the cranial nerves

Recognize the cranial nerve paths
Explain the lesion of cranial nerves
Discuss their clinical features
PAEDIATRICS
1. NEU 2 Ped 1 Causes Of Perinatal Brain Injury
Define perinatal brain injuries

Classify and identify causes of perinatal baring injuries
Describe pathophysiology of the given pathologies
Elaborate management and treatment plans for given pathologies
2. NEU 2 Ped 2 Cerebral Palsy & Mental Retardation
Define cerebral palsy

Explain the types of cerebral palsy
Discuss its prevention and management
Explain mental retardation on the basis of it diagnostic criteria
Differentiate between mild, moderate and severe depression
Discuss its workup and management
3. NEU 2 Ped 3 Approach To And Management Of Stroke In Children
Outline the causes of stroke in paediatric age group

Explain the clinical presentation of children with stroke
Define the steps of approach towards such patients
Describe the details of management plan
4. NEU 2 Ped 4 Leukodystrophies, Wilsons Disease, Sspe,
Define leukodystrophies ,wilsons and SSPE

Describe pathophysiologies of the given pathologies
Identify given pathologies on the bases of clinical features
Elaborate investigation and management plans
5. NEU 2 Ped 5 Approach To Metabolic & Toxic Disorders Affecting Nervous System In
Children
Describe metabolic and toxic disorders common in children

Elaborate the effects of metabolic and toxic disorders on children bain
Identify investigation techniques used to evaluate given pathologies
872
Recognize management plans
6. NEU 2 Ped 6 Approach To Seizure Disorders In Children(Epilepsy)
Define childhood epileptic syndrome

Pathophysiology of the given pathology
Clinical features and risk factors of given pathology
Management plans
7. NEU 2 Ped 7 Neuro Psychotic And Behavior Disorders In Children
Explain enuresis with its types

Elaborate encopresis and its management
Describe autistic disorder with its clinical features
Understand attention deficit disorder
ANAESTHESIA
1. NEU 2 Pre Operative Assessment Of Patient For GA
Define the importance of preoperative assessment

Identify the goal of preoperative assessment
Describe the stepwise components of preoperative assessment
General Anesthesia
Define anesthesia
Describe types of anesthesia
Classify general anesthesia
Roll and uses of general anesthesia
Side effects and complications related to general anesthesia
Regional Anesthesia
Describe anesthesia
Types of Anesthesia
Define regional anesthesia
Types of regional anesthesia
Method of regional anesthesia
Side effects of anesthesia
873
Neurosciences /psychiatry Module:
V. Lumbar Puncture
A procedure in which a hollow needle and stylet are introduced into the subarachnoid space of
the lumbar part of the spinal canal to obtain cerebrospinal fluid (CSF) for therapeutic and
diagnostic purposes. Strict aseptic technique is used.
After the session the students should be able to:
1. Enlist the instrument needed for the procedure.

2. Demonstrate the correct aseptic technique of Lumber Puncture.
1. NEU 2 Cbl 1 HEADACHE
Define headache and its types

Identify type of headache on the basis of clinical features
Describe the investigation criteria for headache
Construct a treatment plan for given pathology
2. NEU 2 Cbl 2 STROKE
Define stroke and its risk factors

Classify stroke
Identify stroke on the basis of clinical presentation and investigations
Outline the treatment options
3. NEU 2 Cbl 3 Parkinsons Disease
Define parkinsonism and Parkinson disease

Describe pathophysiology of Parkinson disease
Identify Parkinson disease on the basis of clinical and investigative grounds
Recognize treatment plan for the given pathology
874
4. NEU 2 Cbl 4 MENINGITIS
Describe meninges and meningitis

Outline risk factors and causes related to meningitis
Rule out meningitis on the bases of CSF findings
Modulate a management plan for the given pathology
5. NEU 2 Cbl 5 BRAIN TUMORS
List the causes of papilloedema.

Describe findings of MRI given.
List differential diagnosis.
Explain diagnostic test, diagnosis on the basis of findings and management of the
given case.
875
Total Subject/ ROUND
WEEKS/HOURS 1st 2nd 3rd 4 5 6 7 8 9 total*100 OFF
10 9.42 9
4 - - 1 - - 2 3 -
Anatomy
6 5.71 6
1 - - 2 - 2 1 -
Pathology
Microbiology 1 0.95 1
- - - - 1 - - - -
11 10.47 10
Pharmacology 1 1 4 3 1 1 - - -
3 2.25 2
Comm.medicie - - - - 1 1 1 -
-
22 20.9 21
Neurology 1 2 2 4 2 3 3 3 2
Peadiatrics - - 1 1 - 1 1 - - 4 3.80 4
Psychiatry 1 1 - 1 1 - 2 1 1 8 7.61 8
Neurosurgery 3 - 1 1 - - 1 2 - 8 7.61 8
Rehabilitation - - 1 - 1 - - 1 - 3 2.85 3
Radiology 1 - - 1 1 1 - 1 - 5 4.76 5
Anesthesia 1 - 2 - - - - - 3 2.85 3
SBL 3 - 3 3 3 3 3 3 21 20 20
-
3 105 99.88 100
TOTAL 16 4 14 15 13 10 15 15
876
(SEMESTER-VIII)
THEORY

SEMESTER
ATP 25
EXAM
PAPER-III 80%
One best Questions
20
based on CBL
Total 100
MODULE EXAM
EMQs 10
ATP 20
MODULE PAPER 20%
One best Questions
20
based on SBL
Total 100
STRUCTURED VIVA

SUMMATIV
ASSESME
SEMESTE
R EXAM
See Semester
NT

E
Assessment Plan
ASSESSMENT TOOLS
Structured Feedback
Facilitator
Paper II & IV-B of Semester-8 Examination are Based on Phy Med/ GEN/ DERMA -2 Module.
877
CREDIT HOURS
SEMESTER VIII
NEUROSCIENCES-2MODULE
PAPER III 6
NEUROSCIENCES-2
PAPER IV C 3
878
CREDIT
HOURS
ENT / EYE Module

40 Marks
I ENT / EYE Module
Marks 3
10 Marks
(Module Exam)
Section - 1
Physical Med Rehab 17 Marks
1-Credit hour
Section 2
Genetics 16 Marks 50
II 1-Credit hour Marks 3
Section 3
Dermatology & Plastic
17Marks
Surgery
1-Credit hour
Neurosciences-2 Module
80 Marks
III Neurosciences-2 Module
20 Marks
Marks 6
(Module Exam)
ENT / EYE-2 Module

A
(Viva)
25 Marks 1.5
IV Physical Med Rehab,
B Genetics 100
Dermatology & Plastic
25 Marks Marks 1.5
Surgery
C Neurosciences-2 (Viva) 50 Marks 3.0
Semester-VIII Total Credit Hours 18
879
880
SPIRAL -3
Integrated Supervised
Practical Training
881
FINAL YEAR M.B; B.S
Semester IX & X
882
Spiral Sem. Modules


4 Week
wks
Second th
Spiral th
Trauma, 6 week
3 week 8 Weeks
/ Burns2 wk
Weeks
th
th
IX &
Third X Lecture on problem based approach, twice a Neurosurgery. 1:30 to 3:00 pm
PARALLEL THEMES:
883
SEMESTER COMMITTEE
Prof. SalahuddinAfsar, Dean of Medicine, DUHS
Prof Naheed Sultan, Dean of Surgery, DUHS
Prof. Khalid Mahmood, Chairperson of Medicine, DUHS
Prof. SaeedQuraishy, Chairperson of Surgery, DUHS
Prof. Junaid Ashraf, Chairperson of Neurosurgery, DUHS
Prof. Ayesha Khan, Chairperson of Gynecology & Obstetrics, DUHS
Prof. Aisha Mehnaz, Chairperson of Paediatrics, DUHS
Prof. KhalidaSomroo, Professor of Cardiology, DUHS
Prof. Maratib Ali, Professor of Orthopedics, DUHS
Dr. Yasmin Hasan, Head of Department of Neurology, DUHS
MODULE COORDINATOR:
Dr. Ateeba Ayesha Khan, Lecturer, Dow Medical College, DUHS
Dr. Ateeba Ayesha Khan, Lecturer, Dow Medical College, DUHS
Module committee
884
RATIONALE
After having completed eight semesters of learning in integrated modular
fashion the student has attained the baseline theoretical knowledge that is
required to practice medicine. The final year is designed to integrate this
knowledge with first hand practical experience to be gained by assigning to the
students a role similar to that of a shadow house officer. The students shall be
posted to clinical teaching units throughout the days teaching time where they
will have practical exposure of management of patients under supervision of
the faculty. The main emphasis of this practical teaching will be on the common
problems of our society that a doctor is most likely to face and be expected to
manage as medical practitioner.
TERMINALOBJECTIVE
By the end of final year the student will have acquired all the competencies that
are required as a doctor in accordance with the guidelines of Pakistan Medical
& Dental Council i.e. being a lifelong self-directed learner, altruistic &
empathetic, having core knowledge of ethics, demonstrate skills of teamwork
as a collaborator, having good communication skills, have developed the spirit
of inquiry, creativity, research oriented attitude and demonstrate leadership
qualities.
885
TEACHING PLAN
Semester Format
SEMESTER ROTATION
For clinical teaching in the final year (IX-X Semesters) the class will be
divided in two groups, one of which will be posted to Medical & Allied
section and the other will be posted to Surgery & Allied section in the IX
semester. In the X semester these groups will exchange and will be
posted to the alternative module.
Clinical Postings Batches

For clinical postings,students have already been divided into clinical
groups(14-18 students in each group) in the third year and have been
doing their clinical postings with the groups.
Each semester shall have 4 months of clinical postings followed by one

month of study leave/ deficit posting. This shall be followed by semester
examination
During each 4 month period the student shall complete following

rotations
a) Medicine & Allied Module
Medicine (2 months)
Paediatrics ( 1 month)
Cardiology ( 15 days)
Neurology ( 15 days)
b) Surgery & Allied Module

Surgery ( 2months)
Gynecology & Obstetrics ( 1 month)
Orthopedics ( 15 days)
Neurosurgery ( 15 days)
The overall semester plan and schedule of rotations for each semester is as
follows.
886
SEMESTER PLAN
SEMESTER IX SEMESTER X
IN MONTHS
Preparation / Preparation /
Semester Semester
Clinical Posting Elective Clinical Posting Elective
Exam Exam
compensation compensation
1 2 3 4 5 6 7 8 9 10 11 12
887
PLAN OF ROTATIONS
CLINICAL Posting Schedule for Semester IX, FINALYEAR MBBS
Posting 1 2 3 4
01-01-15 29-01-15 26-02-15 26-03-15
Units to to to to
28-01-15 25-02-15 25-03-15 22-04-15
Surgery 2 A1 B1 C1 D1
Surgery 3 B1 A1 D1 C1
Orthopedics C1+1st half of D1+1st half of A1+1st half of B1+1st half of
( 15 days ) * C2 D2 A2 B3
Neuro Surgery C3+2nd half of D3+2nd half of A3+2nd half of B3+2nd half of
( 15 days ) * C2 D2 A2 B3
Gyn/Obs 3 D1 C1 B1 A1
Medical 2 E1 F1 G1 H1
Medical 3 st
F1+1 half of st
E1+1 half of H1+1st half of G1+1st half of
F2 E2 H2 G2
Medical 1 nd
F3+2 half of nd
E3+2 half of nd
H3+2 half of nd
G3+2 half of
F2 E2 H2 G2
Neurology G2+1st half of H2+1st half of E2+1st half of F2+1st half of
(15 days ) * G1 H1 E1 F1
nd nd nd nd
Cardiology G3+2 half of H3+2 half of E3+2 half of F3+2 half of
( 15 days ) * G1 H1 E1 F1
Paeds 3 H1 G1 F1 E1
Paeds 1 H2 G2 F2 E2
Paeds 2 H3 G3 F3 E3
(1) Where Batches are to divide, they will divide into two equal halves (1 st half & 2nd half) and
will attend ward as indicated.
(2) Students posted in Neurology / Cardiology/ will interchange after 15 days.
(3) Students posted in Neuro Surgery and Orthopedics will also interchange after 15 days.
(4) Students posted in Orthopedics will report to HOD Ortho I for further posting
888
TEACHING DURING WARD POSTINGS
Students of Final Year MBBS, are posted to allotted wards where they are to perform the following
Patient allocation:
1. Students will be allocated beds in the ward. Equal numbers of male and female beds to
be allocated if possible.
2. Teams of PG- HO- Student will be formed according to beds
3. Students shall take history of their patients.
4. Follow the patients up on daily basis on SOAP format.
5. Students will be encouraged to assist in surgery/procedures of their respective patients.
Ward round with junior faculty/ senior PG:
1. Ward round will be conducted by Assistant Professor or Senior Postgraduate at least

three times of a week.
2. During these rounds 2 to 3 patients will be discussed each day in detail as regards to
their presentation, examination findings, investigations to be performed and findings of
investigations already performed. The management plan will be proposed by the
student.
3. The students will prepare and present their cases.
4. During rounds the students will be encouraged to discuss amongst themselves and the
role of the faculty/PG shall be that of the facilitator.
5. On this format, management of major cases of the specialty will be dealt with.
6. The rest of the WR will be for day to day management of patients.
Ward Work:
1. The student will shadow the house officer and the PG.
2. Will assist in procedures performed by them and will be supervised in minor procedures
to be performed by the students.
3. Will do the ward work along with the house officer.
Topic Discussion
1. At least three times in a week a major topic will be discussed.

2. The topic will be given on the previous day and all the students will prepare the topic.
3. This session will be coordinated by senior faculty member who will act as a facilitator.
4. The students will make presentations and will be discussing these problems amongst
themselves.
5. The discussion will be based on the different scenarios relevant to that particular topic.
Tutorial:
1. Twice a week a tutorial on some important topic of practical application will be

delivered in the ward.
2. Will be delivered either by faculty member or senior postgraduate (in the last two years
of training).
889
WEEKLY SCHEDULE
890
MEDICINE
891
MEDICINE
TOPICS FOR INTERACTIVE & TUTORIAL SESSIONS IN

MEDICINE
POSTING 1 (1st Month)
WEEK TOPIC 1 TOPIC 2 TOPIC 3
Approach to
1ST Approach to
Approach to Anaemia Lymphadenopathy and
WEEK Bleeding Disorders
Hepatosplenomegaly
Approach to Dysphagia Approach to Acute

ND
2 and Dyspepsia-GERD \ Diarrhea and its
Approach to Upper GI Bleed
WEEK APD (including H. Complication
Pylori) including ARF
Approach to Acute
Approach to Chronic Approach to Jaundice and Chronic Liver
3RD
Diarrhea(Malabsorption)/IBD Including Viral Hepatitis Disease with
WEEK
and Celiac Disease and Its management Complications and
HCC
Approach to
Approach to Renal
patients with
Failure and
Approach to Proteinuria and Electrolyte
4TH Differentiation between
Hematuria (Nephritic and Imbalance (Hypo
WEEK ARF and CRF and
Nephrotic Syndrome) and Hypernatremia
Clinical Management and
and Hypo and
Complications
Hyperkalemia
892
TOPICS FOR INTERACTIVE & TUTORIAL SESSIONS IN
MEDICINE
POSTING 2 (2nd Month)
Approach to pneumonia
Approach to Acute (CAP\HAP) its
Approach to chronic
Dyspnea (Bronchial complications including
dyspnea and chronic
1ST Asthma, Pulmonary lung abscess and
chough ( COPD with
WEEK Edema and Pulmonary uncomplicated and
complications, ILD) and
embolism) and its complicated
its management
Management pleuraleffusionand its
management
Approach to
pathophysiology , history
and clinical examination
Diabetes mellitus its Diabetes mellitus and diagnosis and management
diagnosis,investigations its complications ( acute of hypo and hyper
2ND
and its management DKA/ HONK/ thyroidism/ Approach to
WEEK
(including oral and hypoglycemia) and pathophysiology ,history
insulin) chronic) and clinical examination
diagnosis and management
of hypo and hyper
cortisolism
Approach to Approach to with febrile

SLE/systemic sclerosis/ illness ( short and long
Approach to arthritis (
RD MCTD duration )/ approach to
3 mono, poly arthritis,
/dermatopolymyositis patients with fever and
WEEK backache- RA\ seroneg.
(history and clinical unconsciousness
arthritis\ gout)
examination diagnosis
and management)
Approach to HIV and Bacterial endocarditis

TH Approach to tuberculosis
4 its diagnosis, pathophysiology,history
(pulmonary and extra
WEEK complications and and clinical examination,
pulmonary)
management diagnosis and management
893
CARDIOLOGY
TOPICS FOR INTERACTIVE SESSIONS
WEEK DAY 1 DAY 2 DAY 3 DAY 4
Patients with Patients with

ACS valvular
1ST (NSTEMI + Patients with Patients with diseases
WEEK STEMI) heart failure arrhythmias
Patients with
Patients with
hypertension
adult Patients with WARD TEST
2ND and
congenital pericardial
WEEK hypertensive
heart diseases diseases.
crisis
TOPICS FOR TUTORIAL SESSIONS

WEEK DAY 1 DAY 2 DAY 3
DAY 4
Discussion on
routine cases e.g.
ECGinterpretation of Bed side CAD, pericardial
1ST
normal ECG and X-ray -reading. examination effusion, CMP,
WEEK
arrhythmias. skills. rheumatic fever
and infective
endocarditis.
Discussion for
Indication of management
diagnostics evaluation protocol and life
with stress test with style modification,
Counseling of the
2ND thallium spect, interventional
patients and
WEEK echocardiography, procedures and
rehabilitation.
Doppler stress, & TEE surgical
and coronary intervention, WARD TEST
angiography (evidence based
on the site).
894
NEUROLOGY
WEEK DAY 1 DAY 2 DAY 3 DAY 4
1ST Primary headache Secondary Parkinsons

CVA
WEEK headache Disease
2ND Generalized Partial Multiple GBS

WEEK Epilepsy Epilepsy Sclerosis
WEEK DAY 1 DAY 2
1ST WEEK Approach To Comatose Approach On Ataxia

Patient
2ND WEEK Approach On Motor Approach On Numbness

Weakness
895
MAIN LECTURES
List of important topics to be revisited in full class format
MEDICINE
No. Topics
1 Overview of Diabetes Mellitus
2 Interpretation of ABG's
3 Resp. Failure & Artificial Ventilation
4 Fluid & Electrolyte Balance
5 Overview of Dyslipidemia/Metabolic Syndrome/Obesity
6 Osteoporosis/Osteomalacia
7 Overview of Hemolytic Anemia
8 Bone Marrow Transplantation
9 Sepsis & DIC
10 Coagulopathy/DVT/Embolism
11 Overview of Chronic Diarrhea/Malabsorption Syndrome
12 Approach to Renal Failure
13 Overview of Arthritis
14 Overview of HIV
15 Overview of Poisoning
16 Blood Transfusion Medicine
896
CARDIOLOGY
No. Topic
1 Evaluation of chest pain & acute coronary syndrome
2 Rheumatic fever &valvular heart diseases
3 How to diagnose arrhythmias & treat them
4 Hypertension & hypertensive crisis
NEUROLOGY
No. Topic
1 Overview of headache
2 Overview of epilepsy
3 Overview of stroke
4 Overview of movement disorders
897
LEARNING OBJECTIVES: MEDICINE
By the end of the session the student should be able to:
Ward Topics
Approach to patient with Anemia
Define anemia and its various types (nutritional, anemia of chronic illness, hemolytic
and aplastic)
Explain pathophysiology of different types of anemia including hemolytic anemia
(intravascular v/s extravascular, congenital v/s acquired)
Recognize various clinical features of anemia including hemolytic anemia (congenital,
acquired, autoimmune v/s non immune)
Differentiate between various types of anemia on the basis of history and clinical
examination
Enlist and interpret various hematological investigations in evaluating a case of
anemia including various red cell indices and specialized tests
Formulate differential diagnosis on the basis of available investigations
Outline principles of management of various types of anemia
Counsel regarding different types of anemia especially hemolytic anemia
Approach to patients with Lymphadenopathy
Formulate differential diagnosis on the basis of history and clinical examination in a

patient with lymphadenopathy
Define and differentiate between various lymphoproliferative disorders/ plasma cell
disorders
Define various modes of presentations of lymphoproliferative disorders /plasma cell
disorders
Explainpathogenesis of lymphoproliferative disorders / plasma cell disorders
Outline and interpret investigations for lymphoproliferative disorders/ plasma cell
disorders
Define importance of cytogenetics of lymphoma / plasma cell disorders
Outline principles of management of lymphoma / plasma cell disorders
Counsel the patients regarding prognosis in lymphoproliferative disorders / plasma cell
order
Approach to patients with massive Splenomegaly
Formulate differential diagnosis on the basis of history and clinical examination in a

patient with splenomegaly
Define and differentiate between various myeloproliferative disorders
Define various modes of presentations of myeloproliferative disorders
898
Define and differentiate between various types of acute leukemias
Explainpathogenesis of myeloproliferative disorders
Outline and interpret investigations myeloproliferative disorders
Define importance of cytogenetic / molecular aspects of CML
Outline principles of management of various phases of CML
Enlist indications and complications of Bone marrow transplantation
Counsel the patients regarding prognosis in myeloproliferative disorders
Approach to a patient with Bleeding / Clotting Disorders
Enumerate signs and symptoms of bleeding /clotting disorders

Explainpathophysiology of bleeding and clotting disorders
Outline and interpret investigations for bleeding and clotting disorders
Outline management of different bleeding/ clotting disorders including indications of
blood products
Counsel the patients regarding prognosis of bleeding / clotting disorders
Approach to a patient with Upper Gastrointestinal Bleed
Distinguish between upper and lower GI bleed

Distinguish between hematemesis, hematochezia and malena
Enlist causes of upper gastrointestinal bleed
Discuss different clinical features pertinent to different causes
Outline investigations in a patient with upper GI bleed
Enlist risk factors for the outcome of upper GI bleed
Outline management for acute upper GI bleed including variceal bleed
Counsel the patients in relation to management and prognosis
Approach to a patient with Dyspepsia / Dysphagia
Define dyspepsia and dysphagia

Enumerate causes of dyspepsia / dysphagia
Enlist alarmingfeatures of dyspepsia
Elucidate clinical features of dyspepsia /dysphagia
Outline investigations of dyspepsia /dysphagia
Enlist indications for barium studies and endoscopies
Explainpathophysiology of H. pylori, GERD/APD
Enlist investigations for diagnosis of H. pylori infection
Outline treatment of dyspepsia including H. pylori, GERD/APD
Approach to a patient with Acute Diarrhea
899
Define acute diarrhea and distinguish it from chronic diarrhea
Define pathophysiology of absorption of different nutrients and concepts of osmotic,
secretory, inflammatory, infective, factitious
Differentiate between small bowel and large bowel diarrhea including dysentry
Enumerate the causes of acute diarrhea
Explain pathogenesis of different acute diarrhea
Enlist clinical features of dehydration including red flag signs
Outline steps of management
Enumerate complications of acute diarrhea
Approach to a patient with Chronic Diarrhea
Define chronic diarrhea

Enlist different causes of chronic diarrhea / malabsorption
Enlist clinical features of malabsorption
Explain pathophysiology of malabsorption
Enumerate relevant investigations including serologies, endoscopies
Elucidate principles of management in relation to the different etiologies
Approach to a patient with Jaundice Including Acute Viral Hepatitis
Differentiate between pre hepatic, hepatic and post hepatic jaundice

Enlist causes of acute hepatitis including viruses
Explain pathophysiology of acute hepatitis
Enlist clinical features of acute viral hepatitis
Outline and interpret investigations for acute hepatitis
Enlist complications of acute viral hepatitis
Outline management of acute viral hepatitis
Counsel patients regarding prevention (including role of vaccination for hepatitis A and B)
and prognosis
Chronic Liver Disease
Define chronic liver disease and differentiate it from acute liver injury
Enlist signs and symptoms of chronic liver disease
Enlist various causes of chronic liver disease including viral and non viral causes
Enumerate and diagnose different complications of chronic liver disease including portal
hypertension, ascites and SBP, upper GI bleed, hepatic encephalopathy, hepato-renal
syndrome, hepatocellular carcinoma
Outline general and specific management of chronic liver disease and its complications
Counsel patient regarding prognosis of chronic liver disease
900
Approach to a patient with Protienuria (Glomerulonephritis / Nephrotic Syndrome)
Define Micro, Macro and Nephrotic range protienuria

Enlist common causes of micro, macro and nephrotic range protienuria
Define nephrotic and Nephritic syndromes
Enumerate causes of nephrotic and Nephritic syndrome
Elucidate clinical features of nephrotic and Nephritic syndromes
Differentiate between nephrotic and nephritic syndromes on the basis of history,
examination and investigations
Outline management of nephritic / nephrotic syndrome
Enlist complications of nephrotic and nephritic syndromes
Enlist different causes of microscopic and macroscopic hematuria
Outline investigation of a patient with hematuria
Acute Renal Failure / Acute Kidney Injury
Define Acute Renal Failure / Acute Kidney Injury(ARF/AKI)

Define types of Acute Renal Failure including pre renal, renal, post renal azotemia
Enumerate causes of Acute Renal Failure
Elucidate clinical presentations of Acute Kidney Injury
Outline investigations of Acute Renal Failure
Differentiate causes of Acute Renal Failure in relation to history and examination
Outline management of Acute Renal Failure
Enlist indications for Dialysis
Diagnose and treat different metabolic abnormalities in ARF
Decide when to refer/admit the patient
Counsel the patients regarding prognosis
Chronic Renal Failure / Chronic Kidney Disease
Define chronic Kidney Disease (CKD)

Enlist major Causes of chronic Kidney Disease including glomerular, tubulointerstitial
nephritis, vascular, congenital, obstructive
Define Stages of chronic Kidney Disease
Elucidate clinical presentations (Symptoms & Signs) of chronic Kidney Disease
Outline Investigations pertinent to the cause
Enlist complications of chronic Kidney Disease
Outline treatment of Chronic Kidney Disease and complications
Decide when to Refer for dialysis and transplantation
Counsel regarding the prognosis of CKD/ESRD
901
Electrolyte Imbalance
Define normal ranges of serum osmolarity and serum levels of common electrolytes
(Na, K, Cl, HCO3, Ca, Mg,PO4)
Define the calculation of serum osmolarity, total body water, free water deficit,
Sodium deficit, corrected calcium level
Explain compositions of commonly used IV fluids
Enlist causes of Hypo & Hypernatremia, Hypo & hyperkalemia, Hypo &hypercalcemia
Enumerate the clinical features of Hypo & Hypernatremia, Hypo & hyperkalemia,
Hypo &hypercalcemia
Outline other relevant investigations to reach the cause
Outline management Hypo & Hypernatremia, Hypo & hyperkalemia, Hypo
&hypercalcemia
Enlist complications of drugs/fluids used for the treatment of electrolyte imbalance
Approach to patient with Acute Dyspnea
Enlist causes of acute Dyspnea

Define and classify respiratory failure
Assess severity of dyspnea (NYHA, asthma)
Explain pathophysiology of acute asthma
Enlist clinical features of acute asthma
Enlist clinical features of tension pneumothorax
Enlist & interpret investigations to reach to a diagnosis including acute pulmonary
oedema, acute pulmonary embolism, pneumothorax, acute severe asthma / COPD /
respiratory failure
Outline principles of management of each conditions
Outline management of acute severe asthma
Outline management of tension pneumothorax
Enlist indications for ventilatory support including invasive and non invasive modes of
ventilation
Counsel patient about the disease
Approach to patient with Chronic Dyspnea
Enlist and differentiate between different causes of chronic dyspnea including chronic
asthma, COPD, interstitial lung disease, occupational lung diseases
Explain pathophysiology of COPD
Enlist risk factors associated with COPD
Outline investigations to confirm the diagnosis of chronic dyspnea according to the
cause
Differentiate between restrictive and obstructive patterns of PFTs
Outline management of chronic dyspnea
Enlist indications for long term O2 therapy
Counsel the patients regarding smoking cessation
902
Approach to a patient with Pneumonia / Pleural Effusion
Define and classify pneumonia

Differentiate between community acquired & hospital acquired pneumonia
Enlist causative organism of pneumonia
Explain pathogenesis of pneumonia
Enumerate clinical features of pneumonia including typical and atypical pneumonia
Outline investigations of pneumonia
Read X-Ray chest for findings of pneumonia
Decide criteria for admission in general Medical ward as well as Intensive Care Unit
Formulate treatment plan
Enlist complications of pneumonia including pleural effusion
Explain pathophysiology of pleural effusion
Enlist causes and clinical features of pleural effusion
Outline investigations and treatment plan in pleural effusion
Enlist indications for chest tube intubation
Diabetes Mellitus
Define diagnostic criteria for diabetes mellitus (WHO)

Define different types of diabetes mellitus
Explain pathogenesis of diabetes mellitus (type 1 and 2)
Enlist symptoms and signs of diabetes mellitus
Outline management of diabetes mellitus (type1 and 2)
Explain diet and life style modification
Enumerate anti-diabetic drugs including oral hypoglycemic along with modes of
action, and insulin
Enlist side effects of oral hypoglycemic and insulin
Enlist complications of diabetes mellitus
Educate patient regarding treatment and life style modification
Counsel the patient regarding the illness
Acute Complications of Diabetes Mellitus
Enlist important acute metabolic complications in type 1 & 2 diabetes mellitus ( DKA,
HHS, Hypoglycemia)
Differentiate various diabetic metabolic emergency on the basis of clinical signs and
symptoms
Explain pathogenesis of DKA, HHS
Understand all possible precipitants of acute metabolic complications
Outline and interpret the investigations for diagnosis of DKA, HHS, hypoglycemia
Outline management plan in a patient with DKA, HHS, hypoglycemia
Enlist complications of the illness
Educate the patient to prevent these complications
903
Chronic Complications of Diabetes Mellitus&Diabetic Nephropathy
Suspect diabetic nephropathy on the basis of clinical features

Classify stages of diabetic nephropathy (CKD), clinical and histopathological
Outline and interpret investigations in diabetic nephropathy including micro and
macro albuminuria
Explain prevention of nephropathy in a diabetic patient with and without
microalbumin
Outline management plan in diabetic nephropathy including early intervention, late
intervention in terms of ESRD
Diabetic Neuropathy / Retinopathy
Suspect neuropathy in a diabetic patient on the basis of negative and positive sensory
symptoms
Classify various types of diabetic neuropathy
Enlist clinical features of diabetic neuropathy (clinical presentations)
Outline investigations to confirm neuropathy
Outline management of diabetic neuropathy
Enlist complications of diabetic neuropathy
Enlist all ocular complications of DM (cataract, retinopathy and glaucoma)
Classify various stages of diabetic retinopathy (background versus proliferative)
Diabetic Foot
Define diabetic foot

Enlist risk factors for diabetic foot
Classify diabetic foot ulcers
differentiate between ischemic versus neuropathic ulcers
Enlist common pathogens leading to diabetic foot
Explain preventive measures for diabetic foot
Outline investigations in a diabetic foot
Outline management of diabetic foot
Enlist indications for amputation
Hypothyroidism and Hyperthyroidism
Explain pathophysiology of hypo and hyperthyroidism

Enumerate causes of these conditions
Enlist clinical presentations and physical signs
Outline pertinent investigation of hypo and hyperthyroidism
Interpret thyroid function test
Diagnose and manage acute emergency situations
Outline treatment options of both conditions
Enlist side effects of drugs used in these diseases
904
Cushings Syndrome
Explain pathophysiology and its relation with pituitary gland

Differentiate between Cushings syndrome and Cushings disease
Understand the drug Induced Cushing, iatrogenic Cushing
Enumerate clinical features and physical signs
Enlist side effects of corticosteroids
Adrenal Insufficiency
Explain pathophysiology of the illness

Enumerate etiology of adrenal insufficiency
Enlist different clinical presentations according to etiology
Enumerate pertinent physical signs
Outline investigative approach to diagnose adrenal insufficiency
Explain treatment options and how to educate a patient
Deal with an acute adrenal crisis
Approach to patient with Arthritis
Differentiate between mono- oligo- and polyarthritis

Enlist causes of mono- oligo- and polyarthritis
Elicit clinical signs in a patient with joint pain
Explain pathogenesis of arthritis in RA, Gout, sero-negative arthritis
Investigate and interpret various laboratory and radiological investigations in an arthritis
patient
Outline principles of management of RA, Gout, sero-negative arthritis
Enumerate various complications of RA, Gout, sero-negative arthritis itself and its
treatment
Counsel patient about disease and its prognosis
Approach to patient with Connective Tissue Disease
Define Overlap Syndrome / MCTD

Explain pathogenesis of SLE / Scleroderma / Polymyositis
Enumerate signs and symptoms of SLE / Scleroderma / Polymyositis
Enlist various modes of presentations of SLE/ Scleroderma / Polymyositis
Enlist diagnostic criteria of SLE / Scleroderma / Polymyositis
Elucidate and interpret serological Investigations (ANA, Anti ds DNA, ENA)
Outline principles of management of SLE / Scleroderma / Polymyositis
Counsel patients of connective tissue diseases regarding treatment, complications and
rehabilitation
Enlist drugs causing Lupus
Enlist stages of Lupus Nephritis
905
Approach to patients with Fever and altered level of Consciousness
Enlist causes of fever with PUO

Enlist differential diagnosis in patients having fever with altered level of consciousness
Define and differentiate meningoencephalitis / cerebral malaria
Enlist organisms involved in meningoencephalitis including bacterial both acute and
chronic, viral, fungal
Enlist clinical features of meningoenchephalitis /cerebral malaria
Enlist complications of meningoencephalitis / cerebral malaria
Outline investigations in a patient with meningoencephalitis / cerebral malaria
Interpret CSF analysis in different types of CNS infections including bacterial, viral, fungal
and protozoal
Outline management plan in a patient with meningoencephalitis / cerebral malaria
Counsel the patient regarding long term sequelae especially in chronic meningitis /
partially treated cases
Approach to patients with Pulmonary and extra Pulmonary Tuberculosis
Explain pathogenesis of pulmonary and extrapulmonary tuberculosis

Suspect and diagnose pulmonary & extra pulmonary tuberculosis
Suspect and diagnose atypical tuberculosis especially in immunocompromised individuals
Outline investigations to diagnose pulmonary and extra pulmonary tuberculosis
Outline management plan for pulmonary and extra pulmonary tuberculosis, considering
CAT I and CAT II Therapy
Explain radiology of different patterns of pulmonary tuberculosis
Identify ATT induced side effects
Treat tuberculosis in specific circumstances including liver disease, pregnancy, AIDS
Define, diagnose and treat drug resistant tuberculosis including MDR, XDR
Counsel patient with tuberculosis including adherence to treatment, drugs side effect,
and interaction with the family/isolation
Approach to patients with HIV
Define AIDS and HIV

Explain modes of transmission and epidemiology of HIV
Explain virology and immunology in HIV
Explain natural history and staging of HIV
Enlist clinical features of acute HIV
Enumerate different modes of presentation in HIV
Enumerate different diseases in relation to CD4 cell count
Outline investigations to make a diagnosis and evaluate complications
Outline management regarding treatment of primary illness and complications of the
disease
Counsel the patient regarding primary illness, complications, social relationships,
rehabilitation and prevention
906
Infective Endocarditis
Give definition of infective endocarditis

Classify different types of infective endocarditis
Enumerate the common organisms causing infective endocarditis
Explain pathogenesis and risk factors associated with infective endocarditis
Enlist clinical features suggestive of infective endocarditis
Outline investigations to establish a diagnosis
Formulate treatment strategy along with duration and response to therapy
Explain requirement of prophylaxis in different surgical procedures
Enlist complications of infective endocarditis
Counsel the patients regarding treatment / surgery and prophylaxis
LECTURE TOPICS
Overview of Dyslipidemia / Metabolic syndrome/ Obesity
Define and classify dyslipidemia, obesity and metabolic syndrome.

Discuss their pathogenesis.
Recognize and differentiate between various causes and clinical features of secondary
dyslipidemia, obesity and metabolic syndrome.
Enlist and interpret various laboratory investigations in evaluating a case of
dyslipidemia.
Identify various risk factors and risk stratification of various factors in the
management
Discuss the principles of management of dyslipidemia/ metabolic syndrome/ obesity.
Discuss the counseling for different types of dyslipidemia, obesity and metabolic
syndrome.
Overview of Hemolytic Anemia
Define hemolytic anemia and its various types

Discuss the pathogenesis of different types of hemolytic anemia( intravascular v/s
extravascular, congenital v/s acquired).
Recognize various clinical features of hemolytic anemia (congenital, acquired,
autoimmune v/s non immune).
Enlist and interpret various haematological investigations (including various red cell
indices) in evaluating a case of hemolytic anemia.
Formulate the differential diagnosis on the basis of available investigations.
Discuss the principles of management of various types of hemolytic anemia.
Discuss the counseling for different types of hemolytic anemia.
907
Overview of HIV
Define AIDS and HIV

Explain modes of transmission and epidemiology of HIV
Explain virology and immunology in HIV
Explain natural history and staging of HIV
Enlist clinical features of acute HIV
Enumerate different modes of presentation in HIV
Enumerate different diseases in relation to CD4 cell count
Outline investigations to make a diagnosis and evaluate complications
Outline management regarding treatment of primary illness and complications of the
disease
Counsel the patient regarding primary illness, complications, social relationships,
rehabilitation and preventio
Bone Marrow Transplantation
Enlist the indications of bone marrow transplantation

Discuss various types of bone marrow transplantation( allogeneic ,autologous)
Identify Complications of bone marrow transplantation (both early and late)
Discuss graft-versus-host disease (GVHD)
Discuss principles of management of a transplant patient
Osteoporosis / Osteomalacia
Define osteoporosis/ osteomalacia

Discuss various clinical manifestations of osteoporosis/ osteomalacia
Discuss pathophysiology of osteoporosis/ osteomalacia
Identify various risk factors of osteoporosis/ osteomalacia
Identify screening protocol for osteoporosis/ osteomalacia
Diagnose osteoporosis/ osteomalacia
Discuss the principles of management including counseling of osteoporosis/
osteomalacia
Overview of chronic diarrhea/ malabsorption syndrome

1. Define chronic diarrhea and malabsorption syndrome.
2. Enlist the causes of chronic diarrhea and malabsorption syndrome.
3. Discuss the pathophysiology of important malabsorption syndromes like Celiac
Disease, Tropical Sprue, Wipple's Disease.
4. Discuss the pathophysiology of inflammatory bowel disease.
5. Discuss the signs and symptoms of malabsorption syndrome.
6. Enumerate and discuss the various malabsorption tests.
7. Outline the management of chronic diarrhea and important malabsorption
syndromes.
8. Discuss the signs and symptoms of inflammatory bowel disease.
9. Enlist the investigations needed for the diagnosis of inflammatory bowel disease.
10. Outline the management of inflammatory bowel disease.
908
Approach to renal failure
Define acute and chronic renal failure.
Enumerate the causes of acute and chronic renal failure.
Discuss the pathophysiology of renal failure.
Enlist the signs and symptoms of renal failure.
Enlist and interpret the investigations for renal failure.
Outline the management plan.
Discuss the complications of renal failure.
Enumerate the indications for dialysis.
Discuss briefly the concept of hemodialysis and peritoneal dialysis.
Overview of arthritis
Classify arthritis according to the onset and number of joint involvement.
Classify arthritis according to the etiology.
Discuss the pathophysiology of rheumatoid, osteoarthritis, gout and seronegative
arthritis.
Enlist the investigations needed for different arthritis.
Discuss the radiological findings in different arthritis.
Interpret the synovial fluid analysis.
Outline the management plan.
Sepsis & DIC

Define SIRS & Sepsis
Discuss the Pathophysiology of Sepsis
Discuss the Signs & Symptoms of Sepsis
Discuss the management of Sepsis
Define DIC
Discuss Pathophysiology of DIC
Enlist the Causes of DIC
Enlist the Investigation needed to diagnose DIC
Discuss the Management of DIC
Coagulopathy / DVT / Embolism
Define the Coagulation disorders

Discuss the defect in coagulation cascade
Enumerate the Signs & Symptoms of Coagulation disorders
Outline the management of coagulation disorders
Define DVT
Enlist the causes of DVT
Discuss the pathophysiology of DVT
Enlist the signs & symptoms of DVT
Define the embolism (Air, Amniotic, Fat, Clot)
Enlist the predisposing conditions of Embolism
Outline the management of DVT with emphasis on anticoagulation therapy
Discuss the anticoagulants and their mode of action
909
Overview of diabetes mellitus
Describe the pathophysiology of diabetes mellitus
Enlist the different types of DM
Enumerate the clinical features of DM
Outline the basics of management of DM
Enlist the microvascular and macrovascular complications of DM
Interpretation of ABGs
Understand the basics of arterial blood gases

Know the normal values of ABGS
Know when to order the test
Enumerate different types of ABGs
Differentiate between acidosis and alkalosis
Enlist causes of all 4 basic varieties of ABGs
Understand the change in hemoglobin dissociation curve in relation to ABGS
Respiratory failure and mechanical ventilation
Understand type I and II respiratory failure

Enumerate the causes of type I and II respiratory failure
Discuss different methods of oxygen therapy and use of different devices
Understand the oxygen therapy in both types of respiratory failure
Management of type II respiratory failure in relation to oxygen therapy and
mechanical ventilation
Enumerate different modes of mechanical ventilation including CMV, SIMV, CPAP
Understand the role of PEEP in type I respiratory failure
Enlist the indications for mechanical ventilation
Fluid and electrolytes balance
Enlist different types of derangements in electrolytes

Enlist the causes of these electrolytes imbalances
Enlist the salient clinical features of these electrolytes disturbances
Discuss methods for calculating different electrolytes deficit and how to replace them
Discuss different fluids available in market like 0.9% saline, 0.45% saline, 3% saline,
5% D/w, 0.45% D/Saline, 0.9% D/Saline, ringer lactate,20 mEq potassium solution,
25% D/W
Discuss use of these solutions at appropriate deficiencies
910
Overview of poisoning
Enlist common types of poisoning including organophosphorous compounds,

atropine, halothane, benzodiazepams, narcotics, alcohol, corrosives, carbon
monoxide
Enumerate clinical presentations of these poisoning
Discuss the immediate management of these poisoning
Enlist the complications of these poisoning
Discuss the long term management including rehabilitation if required
Counsel the patient and family regarding the consequences of these poisoning
Blood transfusion methods
Discuss different types of blood transfusion methods

Enlist different blood products available like whole blood, packed cell, platelets, white
cell, fresh frozen plasma
Enlist indications for use of these blood products
Discuss complications associated with blood product transfusion itself and of
different varieties of blood products
Discuss care of blood products
EMERGENCY LIFE SAVING SKILLS FOR MEDICINE
Title of skill: Introduction to Defibrillation.
Introduction:
Defibrillation by Automated External Defibrillators or Manual Defibrillators is a life-saving
skill during cardiac arrest. Learning proper technique of defibrillation is essential for every
healthcare professional working in emergency and intensive care settings.
After this session students should be able to:
List the equipment required for this procedure.
Demonstrate correct technique of defibrillation by a manual defibrillator.
Title of skill: Management of Respiratory Arrest.
Introduction:
Airway management is an essential part of any emergency medical intervention in cases of
cardiac or respiratory arrest. Proper use of basic and advanced airway adjuncts is a
fundamental skill for all tiers of health care professionals.
911
List the equipment required for this procedure.
Demonstrate correct technique of insertion of basic and advanced airways with
precautions.
CARDIOLOGY
Patient with chest pain
Analyze history and examination of the patient with ischemic heart diseases.
Able to differentiate the clinical presentation of various ischemic presentations.
Able to predict risk score for management plane.
Read ECG and laboratory test investigation Troponin and CK-MB.
Correlate the clinical presentation with reports of the advanced investigation like
ECHO and Coronary Angio and Thallium Spect.
Describe the management plane of specific ischemic disorders.
Patient with cardiac failure
Analyze the history and examination of cardiac failure presentation.

On the clinical presentation try to find the cause of cardiac failure.
Read ECG and X-Ray finding.
Correlate the clinical presentation with echocardiography reports finding.
Describe the management.
Patient with hypertension
Analyze and the history and examination specially BP taking procedure in a patient
with hypertension.
Able to Grade the level of blood pressure.
On the clinical presentation try to identify the secondary cause end-organ damage.
Assess cardiovascular risk factors.
Analyze the appropriate test for secondary cause e.g. ultrasound abdomen KUB
thyroid profile etc.
Analyze the appropriate test for end-organ damage documented on clinical
presentation. (U &Es, urinalysis, creatnine, ECG, Fundascopy, ECHO).
Describe the management.
Patients with valvular diseases
Analyze history and examination of the rheumatic valvular heart diseases

presentation.
On the clinical presentation try to find diagnosis of the specific valular involvement.
Read the ECG Chest X-Ray finding.
Correlate clinical finding with the reports of Echocardiography finding.
Describe the management and prophylaxis.
912
Patients with arrhythmias
Analyze the history and examination of patient with arrhythmias.

On the clinical presentation try to clarify the nature of arrhythmias
Try to find the cause of arrhythmias.
Know the importance of advance investigation for the management plain 24 hours
Ambulatory ECG, ECHOCARDIOGRAPHY, EP studies, Laboratory test.
Describe the management plane of specific arrhythmias.
Patient with adult CHD:
Analyze the history and examination of Cyanotic Heart disease presentation.

On the clinical presentation try to find the diagnosis of the congenital heart diseases.
Read ECG, Chest, X-Ray finding.
Correlate the echocardiography findings with clinical presentation.
Describe management plane.
NEUROLOGY
Approach To Patient with Headache:
Record accurate neurological history.

Perform complete as well as customized neurological examination
Able to perform fundoscopic examination
Able to recognize red flags signs related to headache.
Able to differentiate between different types of primary headache disorders.
Approach To Patient with Epilepsy:

Able to differentiate between different types of epilepsies.
To know the indications ,contraindications and side effects of different
antiepileptic drugs
Able to know different treatment options for refractory /resistant epilepsy
913
Approach To Patient with stroke/Motor weakness:

Localize the lesion indifferent parts of nervous system on the basis of history
and examination in patients with motor weakness.
Able to perform immediate and routine investigations in patient with
weakness.
Able to perform immediate management in patient with stroke
Able to know usage, indication and contraindication of TPA
Approach To Patient with Parkinsons disease:

Able to know the differential diagnosis of patients with parkinsonism
Able to know the different management plans of patient with Parkinson
disease
Approach To Patient with Multiple sclerosis:

Localize the lesion indifferent parts of nervous system on the basis of history
and examination.
Able to know different types and management of patients with multiple
sclerosis
Approach To Patient with Numbness and GBS:

Able to know differential diagnosis in patients with numbness
Able to differentiate demyelinating and axonal diseases on EMG/NCVs
Able to recognize and manage patients with acute neuropathy e.g. GBS
914
Approach To Patient with ataxia:

Perform complete as well as customized neurological examination in patients
with ataxia
Able to know the differential diagnosis of ataxia
Able to investigate the treatable causes of ataxia
Approach to comatose patient:
Record brief history and tailored neurological examination

Able to know the neurological and non-neurological causes of coma
Able to know the immediate investigations in patients with coma
Able to know the immediate management plans in patients with coma.
915
CREDIT HOURS OF MEDICINE
13.5
Marks distribution of each paper is given below
Passing of both written and clinical examination is essential. Failure in one

component requirets retake of both written and clinical examination.
916
EXAMINATION PATTERN FOR MBBS FINAL YEAR SEMESTER IX- X

Medicine & Allied
The assessment shall be:
a) Continuous assessment
b) Terminal assessment
CONTINUOUS ASSESSMENT:
Continuous clinical assessment is done at the end of the clinical posting. The students are
provided feedback which is one of their formative assessments
SEMESTER ASSESMENT:
Exam to be conducted at the end of the semester (semester system)
This shall have:
a) Written examination.
b) Clinical examination including viva.
917
WRITTEN EXAMINATION
Total Marks 400

Marks of theory component 300
Marks of non interactive viva stations 100
Medicine will have two theory papers. the distribution of topics for Medicine Paper-I &
Medicine Paper-II is given below.
Each written paper shall be of 200 marks with the following distribution.
Each paper of written assessment shall consist of 75 questions of BCQ format.

All questions will be preferably short scenario based.
150MARKS
Twenty five questions in each paper will be based on photograph/

diagrams/ECG or graphs. (alternative to practical) to be graded with the
clinical examination. This component consist of Noninteractive Stations Viva
and the marks obtained will be counted toward clinical examination
50 MARKS
918
CLINICAL EXAMINATION
Total Marks 200
The practical examinations in Medicine shall consist of total 10 stations.

The following 07 stations of 20 marks each are interactive and based on:
History taking
Management
Counseling
X-rays and table vivas in Medicine
Short case
Short case
Short case
TOTAL= 140 MARKS
In addition, 03 non-interactive stations of 20 marks each shall be included. These stations
should consist of clinical scenarios along with X-rays/ECGs/photographs/Instruments
based on the following subjects:
1. Cardiology
2. Cardiology
3. Neurology
TOTAL= 60 MARKS
919
MEDICINE PAPER 1 DIVISION
S. No Topic
1 Respiratory System
2 Cardiovascular System
3 Gastrointestinal tract system
4 Musculoskeletal Disorders
5 Hepatobiliary System
6 Nutritional and Environmental diseases
7 Dermatology
8 Clinical Genetics
9 Oncology
10 Immunological Disorders
MEDICINE PAPER 2 DIVISION

S.No Topic
1 Central Nervous System ( Neurology)
2 Endocrine Diseases + Diabetes Mellitus
3 Infectious Diseases
4 Haematology
5 Kidney and Genitourinary Diseases
6 Water, Electrolyte and Acid Base Balance
7 Clinical Pharmacology
8 Psychiatry
9 Poisoning / Snake Bite/ Insect Bite
10 Metabolic Disorders
920
ASSESSMENT PLAN (MARKING GRID)
ASSESMENT PLAN OF SEMESTER IX- X (MEDICINE MODULE)

ASSESMENT TOOLS MARKS
PAPER 1
SEMESTER/ ANNUAL EXAM
SCENARIO BASED 50
QUESTIONS (ATP)

PAPER 2
SCENARIO BASED 50
QUESTIONS (ATP)
INTERACTIVE 140
CLINICAL STATIONS(TOTAL =7)
ASSESSMENT
NON-INTERACTIVE 60
STATIONS( TOTAL=3 )
921
MARKS ALLOCATION
Theory:
Paper 1: 150 marks to be assessed in written paper BCQ component
Total: 300 marks
Clinical assessment:
1) Alternative to Practical: 100 marks to be assessed in written paper ATP
component
2) Clinical Examination: 200 marks
Total: 300 marks
922
PAEDIATRICS
923
PAEDIATRICS
TOPICS FOR INTERACTIVE& TUTORIAL SESSIONS
WEEK TOPIC 1 TOPIC 2 TOPIC 3 TOPIC 4
Diarrhea Nephritic AGN

1ST PCM IMNCI
Malabsorption
WEEK
Hemolytic anemia AFP meningitis

2ND IMNCI
PCM Nutritional anemia
WEEK
Interviewing and Enteric fever malaria

Asthma and Congenital heart
3RD counseling skill
counseling disease
WEEK (Down Syndrome)
Pneumonia / pleural Ward Test

Examination of New CLD and
4TH effusion
born counseling
WEEK pneumothorax T.B
924
MAIN LECTURES
PAEDIATRICS
No. Topics
1 History taking & examination of children & newborn
2 Overview of nutrition & PCM
3 Overview of IMNCI
4 Overview of neonatal problems
925
LEARNING OBJECTIVES
PAEDIATRICS
Nutrition
How to define and clarify malnutrition.

What are the risk factors for malnutrition
Explain how to evaluate the signs and symptoms of malnutrition.
Give management of Malnutrition.
Describe optimum breast feeding practices.
Enlist Advantages of breast feeding and disadvantages of bottle feeding.
Explain different position and attachment of breast feeding.
Counsel parents for breast feeding.
IMNCI
Describe different components of IMNCI program.

How to ask question (history) according to IMNCI.
How to fill the programs for IMNCI (Bedside)
How to classify and teat the problem according to IMNCI.
Manage children and newborns in OPD and IPD according to IMNCI. (Bedside)
Do follow up according to IMNCI.
Oncology ALL, Lymphoma and Solid tumor
Describe incidence of childhood malignancies

Define ALL, and lymphoma.
Describe etiology of ALL / lymphoma.
Give presentation of different malignancies in children
Describe how to Investigate malignancies in children
Describe how to Manage malignancies in children
Interviewing and counseling skills

Technique of counseling.
Counsel parents for chromosomal disorder (Down syndrome).
UTI, AGN and Nephritic Syndrome
Define UTI, AGN and Nephrotic syndrome.
926
Presentation of these problems
Risk factors and etiology of UTI.
How to investigate these problems.
How to manage these problems.
Relapse, frequent relapses, steroid dependent, steroid sensitive and steroid resistant
nephritic syndrome.
Indications of renal biopsy.
Follow up these patients.
Diarrhea and Malabsorption
Assess classify and treat dehydration

Etiology aid risk factor for diarrhea
List malabsorption disorders
Celiac disease in detail
Investigate and manage a child with malabsorption
Counsel parents for celiac disease.
Respiratory system Pneumonia, Asthma, Pleural effusion, Pneumothorax
How to define Pneumonia, Asthma, Pleural effusion, Pneumothorax

Examine a child with respiratory problem
How to diagnose these problems.
How to manage these problems.
How to use peak flow meter, nebulization and inhalers
Different grades / stages of Asthma
Acute and chronic liver disease
Define acute and chronic liver disease.

Cause of acute and chronic liver disease.
Presentation of CLD
Investigate and manage CLD.
Counsel parents for CLD.
Hemolytic anemia and nutritional anemia
Define anemia
Different types of hemolytic anemia
Presentation of hemolytic and Nutritional anemia
Investigate hemolytic and nutritional anemia
Manage hemolytic and nutritional anemia
Counsel parents for hemolytic anemia.
927
CVS
List common cyanotic and acyanotic heart disease
Presentation of congenital heart disease.
VSD, TOF in detail
Define Rheumatic fever and its presentation.
Criteria for diagnosis rheumatic fever.
Mange rheumatic fever
Complications of rheumatic fever.
CNS (Meningitis, encephalitis and AFP)
Define Meningitis, encephalitis and AFP

Exam a child with a neurological problem.
Etiology of Meningitis, encephalitis
Complication of Meningitis, encephalitis
How to investigate these problems.
Causes of AFP.
Presentation investigate and prevention of Polio
Infections disease (enteric fever, malaria, vaccine preventable disease)
Burden of infection disease.

Presentation of these infections
Investigation and management of these infections.
Define vaccine.
List disease that is prevented by vaccine.
Vaccination schedule.
Endocrinology (Short Stature, Hypothyroidism and diabetes mellitus)
Presentation of Short Stature, Hypothyroidism and diabetes mellitus in children

Screening for hypothyroidism in newborns.
How to Investigate and manage Hypothyroidism and diabetes mellitus in children
Diabetic ketoacidosis in children.
How to define short stature
Causes of short stature in children.
How to Evaluate short stature
Counseling of a diabetic child.
Neonatology (preterm, low birth weight, birth asphyxia, neonatal jaundice and sepsis)
Define these terms.

Causes of these problems
How to Investigate these problems
How to Manage these problems
APGAR score
928
Examination of Newborn
How to do neonatal examination
Neonatal reflexes
Assessment of gestational age
EMERGENCY LIFE SAVING SKILLS FOR PAEDIATRICS
Introduction:
In this course; there is a systemic approach for seriously ill or injured child. If not adequately
treated, child can quickly progress to cardiopulmonary failure leading to cardiac arrest.
The aim of this course is to enable students to recognize respiratory distress and failure,
cardiac arrest & shock, so that they can provide lifesaving interventions.
1. Describe the systematic approach to pediatric assessment by using

a) Primary assessment
b) Secondary assessment
c) Diagnostic tests
2. To manage respiratory emergencies
3. Identify the correct sites of Intra-osseous access, and demonstrate the correct
techniques
929
CREDIT HOURS OF PEADIATRICS
4.5

930
EXAMINATION PATTERN FOR MBBS FINAL YEAR
SEMESTER IX- X
PAEDIATRICS

CONTIONUOS ASSESSMENT
Continuous clinical assessment is done on monthly basis as marks obtained in the final year
clinical postings of the related subjects
TERMINAL ASSESMENT
Exam to be conducted at the end of the semester (semester system) or at the end of the year
(annual system).
Each subject shall have a) clinical examination b) written paper
WRITTEN PAPER
Pediatrics will have one theory paper.
Each paper of written assessment shall consist of
75 questions of BCQ format. All questions will be preferably short scenario based.
150 marks
25 questions will be based on photograph/ diagrams/ECG or graphs. (alternative to

practical) to be graded with the clinical examination
50 marks
931

SEMESTER IX- X
PEDIATRICS
SEMESTER ASSESMENT:
This shall have:
932
WRITTEN EXAMINATION
Total Marks 200

Pediatric semester examination will have one theory paper.
The written paper shall be of 200 marks with the following distribution.
The paper of written assessment shall consist of 75 questions of BCQ format.

150 MARKS
Twenty five questions in the paper will be based on photograph/

diagrams/ECG or graphs. (alternative to practical) to be graded with the
clinical examination. This component consist of Noninteractive Stations Viva
and the marks obtained will be counted toward clinical examination
50 MARKS
933
TOTAL 100 MARKS
The practical examinations in Pediatrics shall consist of total 10 stations.

History taking
Management
Counseling
X-rays and table vivas
Short case
Short case
Short case
TOTAL= 70 MARKS
TOTAL= 30 MARKS
934
PAEDIATRICS
CONTENTS OF THE PAPERS: THE ENTIRE SYLLABUS INCLUDING:
Nutrition
Acute Respiratory infections (ARI) and IMNCI
Diarrhea
Neonatology
Blood
Nephrology
Liver / GIT system
Respiratory System
Cardiovascular System
CNS
Endocrine
Infectious Diseases
Immunization
Growth & development Psychiatric Disorder
Musculoskeletal
Genetics Metabolic
Skin
Accidental Poisoning
Rheumatic Disease
Neonatal Resuscitation
935
ASSESMENT PLAN OF SEMESTER IX- X (MEDICINE MODULE)
WRITTEN PAPER One best Questions 150
SEMESTER/ ANNUAL
SCENARIO BASED 50
QUESTIONS (ATP)
EXAM
INTERACTIVE 70
ASSESSMENT
NON-INTERACTIVE 30
STATIONS( TOTAL=3 )
936
MARKS ALLOCATION
Theory:
Total: 150 marks
Alternative to Practical: 50 marks to be assessed in written paper ATP
component
Clinical Examination: 100 marks
Total: 150 marks
937
SURGERY
938
SURGERY
TOPICS FOR INTERACTIVE SESSIONS IN SURGERY

POSTING 1 (1st Month)
1ST Acute Abdomen Gall Bladder Diseases Acute Appendicitis

WEEK
Acute Pancreatitis. Right lower abdominal

2ND Obstructive Jaundice.
masses
WEEK
Space occupying lesions

3RD of liver
Hernias Testicle
WEEK
Surgical diseases of the

4TH Vascular Diseases Pre-operative Workup
breast
WEEK
939
TOPICS FOR INTERACTIVE SESSIONS IN SURGERY
POSTING 2 (2nd Month)
Dressing Suture &

1ST Intestinal obstruction
Instruments Dysphagia
WEEK
2ND Swellings of the neck Stomach

Genitourinary diseases
WEEK
3RD Colorectal diseases Postoperative Care Perianal Diseases

WEEK
4TH
WARD TEST
WEEK
940
NEUROSURGERY
WEEK DAY 1 DAY 2 DAY 3 DAY 4 DAY 5
Cerebro-
Head Injury and Spinal Injury & Vascular
1ST Brain Tumors Degenerative
Management Management Accidents
WEEK Spinal Diseases
Approach to
Neurological Reading Reading MRI Approach to
2ND Patient with
Assessment Head CT Scan Head and Spine Patient with
WEEK Head Injury
Spinal Injury
941
LEARNING OBJECTIVES
ORTHOPEDICS
WEEK DAY 1 DAY 2 DAY 3 DAY 4 DAY 5
Basic Upper limb

orthopedic History & fracture
1ST Congenital Lower limb
terminologies & orthopedic recognition
WEEK disorders fracture
fracture examination
classification recognition
Acquired/ Arthritis
Radiological Orthopedic
2ND metabolic
Bone tumor interpretation techniques
WEEK disorders
942
SURGERY
NO. TOPIC
1. Management of acute burns
2. Diagnostic and therapeutic radiology used in surgery
3. Pain: Theory and management
4. Principles of oncology including staging and management of tumors
5. Urinary stones
6. Breast tumors
7. Tumors of the genitourinary tract including testicular excluding prostate
8. Shock, including investigation and management of sepsis
9. Prostate
10. Disorders of the esophagus
11. Pancreatic disorders including NET
12. Arterial disorders
13. Deep vein thrombosis including management of complications
14. Anatomy of the anterior abdominal wall and management of hernias
15. Gall bladder and biliary tract disease including complication of gall stones
16. Colonic disorders including large bowel obstruction and IBD
17. Rectum and perineal disease
18. Thyroid disease
19. Organ transplantation
943
NEUROSURGERY
No. Topic
1 Head Injury and its management
2 Brain & Spinal Tumors
3 Cerebrovascular Accidents
4 Degenerative Spinal Disorders
ORTHOPEDICS
No. Topic
1 Fracture Management
2 Osteoarthritis
3 Osteomyelitis-acute & chronic
4 Metabolic bone disease
944
WARD TOPICS: LEARNING OBJECTIVES
SURGERY
Objectives:
At the end of the posting in surgery ward the final year medical student will be able to:
1. Take a detailed history from a surgical patient, relatives and others.
2. Perform a complete physical examination of a surgical patient.
3. Present a summary of at least one assigned case to a faculty member during a ward
round.
Acute Abdomen
Enlist the common causes of acute abdomen in order of frequency.

Analyze the history taken from a patient and be able interpret the findings to
identify the cause for the acute abdomen.
Demonstrate to the faculty member the logical way of examining a patient
suffering from acute abdomen.
Describe a management strategy for a patient suffering from acute abdomen.
Gall Bladder Diseases
Diagnose a patient suffering from gall bladder diseases on the basis of a focused
history and examination.
Plan and justify required investigations in gall bladder diseases.
Outline a management plan for a patient most likely suffering from gall bladder
diseases presenting to the emergency ward / OPD of the hospital.
Obtain an informed consent from a patient or his/her family member for
laparoscopic cholecystectomy and possible conversion to an open procedure with
reasoning.
Acute Appendicitis
Elicit a focused history from a patient suffering from acute appendicitis so as to

reach a working diagnosis.
Perform a focused examination in a patient with right lower quadrant pain.
945
Describe a management plan including surgical options for a patient suffering
from acute appendicitis and its complications.
Counsel a patient with acute appendicitis and its complication for any required
intervention.
Acute Pancreatitis
Enlist the causes of Acute Pancreatitis.

Record a pertinent history from a patient most likely suffering from acute pancreatitis
and be able to reach a working diagnosis.
Develop a management plan for a patient suffering from acute pancreatitis.
Counsel a patient suffering from acute pancreatitis about the management plan and
justify the utilization of surgical options if needed to be proceeded on.
Obstructive Jaundice
Enlist the most common causes of obstructive jaundice in a sequential manner.

Take a focused history from a patient suffering from obstructive jaundice to reach
a rational cause for the same.
Write and justify a management plan for a patient of obstructive jaundice and its
complication.
Obtain an informed consent from a patient who is to undergo an elective
Endoscopic Retrograde Cholangio-Pancreatography (ERCP) with all possible
outcomes related to the procedure.
Right lower abdominal masses
Enlist the common causes of right lower abdominal masses in order of frequency.
Justify the most likely cause of the right lower abdominal mass on the basis of history
and physical examination in a given patient.
Space occupying lesions of liver
Enlist the most likely causes for a space occupying lesion of the liver.
Justify a working diagnosis for an abscess of the liver on the basis of history and
946
Describe a management strategy for a patient suffering from a malignant space
occupying lesion of the liver.
Outline a management plan for a patient suffering from a complicated hydatid
cyst of any part of the body.
Obtain an informed consent from a patient who is to undergo Percutaneous
drainage of echinococcal cysts (PAIRPuncture, Aspiration, Injection, Re-
aspiration) with possible complications and options for emergency surgery.
Hernias
Reach an accurate diagnosis on the basis of history and physical examination.

Illustrate with complete accuracy the difference between an inguino-scrotal and
scrotal swelling.
Demonstrate with judicious precision the difference between a femoral, indirect
and direct inguinal hernia during physical examination.
Differentiate with complete precision between a reducible and irreducible
inguinal hernia during physical examination.
List the baseline investigations needed for pre-operative workup of an inguinal
hernia patient.
Discuss the disease specific investigations need for pre-operative workup for an
inguinal hernia patient.
Compose a post-operative treatment plan for a patient of inguinal hernia.
Explain the difference between obstructed and strangulated hernia.
Formulate a comprehensive management plan for the given patient of inguinal
hernia including surgical procedures.
Employ accepted guidelines for attaining an informed consent from a simulated
patient of inguinal hernia who is to undergo elective surgery.
Testicle
Order and interpret appropriate investigations including tumour markers in a patient

with testicular tumour.
Stage accurately a patient with testicular tumour.
Outline a management plan for a testicular tumour.
Formulate a plan for managing a case of undescended testis.
Counsel an adult patient who is to undergo surgery for an undescended testis.
Differentiate testicular tumors from other scrotal swelling on the basis of clinical
examination.
Surgical diseases of the breast
Justify the diagnosis on the basis of history and physical examination of a patient
presenting with a breast lump.
Propose a management plan for a patient who has been diagnosed as a benign
breast disease.
947
Devise a management strategy on the basis of current scientific evidence for a
patient diagnosed as having a malignant breast disease.
Obtain an informed consent from a patient who is to undergo a modified radical
mastectomy with axillary sampling, explaining all common possible outcomes.
Counsel a patient diagnosed as having malignant breast disease about the future
management with the possible options of chemotherapy and radiotherapy.
Vascular Diseases
Interpret the clinical findings to achieve a working diagnosis in a patient presenting

with a lower leg ulcer and manage such a patient.
Summarize a management approach for a patient diagnosed as having peripheral
vascular disease.
Construct a plan for management of a patient diagnosed as having diabetic foot.
Obtain an informed consent from a patient who is to undergo surgery for varicose
veins.
Obtain an informed consent from a patient undergoing lower limb amputation.
Justify the pre-operative workup of a patient who is to undergo elective surgery.
Dressing Suture & Instruments
Choose the appropriate suture material in the context of the tissue

characteristics.
Select the appropriate dressing and care for surgical wounds on the basis of
surgical principles.
Select the correct Tube/Drains depending on the situation of the surgical
procedure.
Pre-operative Workup
Select and interpret the correct baseline investigations for the pre-operative
workup of a patient with co-morbidities undergoing elective or emergency
surgery.
Order and interpret the findings of plain radiograph, C.T. Scan and M.R.I. in
relations to the disease.
Evaluate the laboratory investigation ordered for pre-operative workup in a
surgical patient.
Prescribe Deep Venous Thrombosis prophylaxis to a high risk patient about to
undergo major abdominal surgery.
Discuss with a patient as how to maintain adequate warfarinization, who might
suffer Pulmonary Embolization secondary to past deep venous thrombosis.
Design a complete nutrition plan including pre-operative support and post-
operative therapy for a patient who is to undergo major abdominal surgery and
will have an ICU stay of 3 days.
948
Should be able to perform the following procedures:
Vene-puncture and intravenous cannulation

Local anesthetic infiltration
Blood culture from peripheral and central sites
Subcutaneous, intra-dermal, intramuscular and intravenous injection
Intravenous medication
Intravenous infusions including perfusion of fluid, blood and blood products
Urethral catheterization
Airway care
Nasogastric tube insertion
Complete a laboratory / histopathology form for a relevant disease.
Dysphagia
Interpret the findings on the taken history to diagnose the patient presenting with
dysphagia.
Devise a plan to manage a patient with Carcinoma Oesophagus.
Formulate a management strategy, based on surgical principles, for the management
of a patient presenting with dysphagia most likely due to a non-malignant cause.
Formulate a nutrition support plan for a patient undergoing an Oesophagectomy with
emphasis on both pre and post-operative stages.
Counsel a patient of Carcinoma Oesophagus about the future management and
possible outcome of the disease.
Intestinal obstruction
Analyze the history from a patient presenting with possible intestinal obstruction
and pinpoint the most likely pathology.
Justify a fluid and electrolyte correction regimen for a patient in intestinal
obstruction.
Outline a strategy to manage a patient with intestinal obstruction.
Propose a nutrition plan which includes both enteral and parental components for
a patient who has undergone small bowel resection.
Colorectal diseases
Enlist the common causes of lower gastro-intestinal bleeding in a logical manner.

Analyze a history from a patient and be able interpret the findings to identify the
specific cause for the lower gastro-intestinal bleeding.
Describe a management strategy for a patient suffering from lower gastro-
intestinal bleeding.
Diagnose a patient with inflammatory bowel disease (ulcerative colitis and
Crohn's) on the basis of history and examination.
Order and interpret appropriate investigations in a patient with inflammatory
bowel disease.
Design a management plan for a patient with inflammatory bowel disease.
Select the appropriate site and type of stoma formation in a given patient on the
949
basis of given surgical principles.
Identify the complications of stoma on a patient.
Counsel a given patient regarding stoma formation following abdominal-perianal
resection for carcinoma rectum.
Enumerate the types and classification of intestinal fistulas and transcribe
management options for intestinal fistulas on a given patient.
Swellings of the neck
Enlist the common causes of neck swelling.

Justify the most likely cause of the neck swelling on the basis of history and
physical examination in a given patient.
Devise a management plan including medical, surgical and nuclear medicine
options for a patient with goiter.
Obtain an informed consent from a patient who is to undergo total thyroidectomy
for a hyperthyroid goiter at present in a euthyroid state.
Stomach
Interpret the clinical findings to achieve a working diagnosis in a patient presenting

with gastric outlet obstruction.
Summarize a management approach for a patient diagnosed as gastric carcinoma.
Genitourinary diseases
Diagnose a patient suffering from renal calculi on the basis of history and physical
examination.
Propose a management plan based on surgical principles for management of a
patient with renal calculi.
Enumerate the causes of haematuria.
Devise a working plan to accurately identify specific cause of haematuria in given
patient.
Formulate a working plan for management of a patient with renal tumour.
Interpret the findings on the basis of history and examination in a patient suffering
from renal tumour.
Elicit a pertinent history so as to be able to reach a diagnosis from a patient
suffering from benign prostatic hypertrophy.
Outline a management plan for a patient suffering from urinary bladder outlet
obstruction.
Postoperative Care
Rationalize the use of various intravenous fluids available for utilization in a given
situation.
Select the appropriate routes and lines for providing nutrition to a patient in the
ward following admission for poly-trauma.
Justify the correct pain therapy for a given patient as W.H.O guidelines.
Prescribe adequate pain management, including epidural and patient controlled
950
analgesia to a patient who has undergone a Thoracotomy
Plan analgesia therapy for a poly-trauma patient who has multiple rib fractures
and lung contusion.
Select the suitable blood products available for transfusion in a given patient as
per transfusion indexing protocol.
Manage the possible complications arising from blood transfusions.
Complete a confirmation of death protocol certificate as per given hospital
guidelines.
Take follow-up of a postoperative patient in SOAP format.
Perianal Diseases
Diagnose on the basis of history and examination a patient presenting with

common perianal problem.
Fistula-in-Ano
Anal Fissure
Perianal &Ischiorectal Abscess
Haemorrhoids
Design a management plan for a patient suffering from Perianal Diseases.
Obtain an informed consent from a patient undergoing perianal surgery.
EMERGENCY LIFE SAVING SKILLS: TRAUMA
Title of skill: emergency lifesaving skills (trauma)
Introduction:
Trauma is the leading cause of death in ages 1-44 yrs. The aim of this module is to to provide
basic knowledge and skills necessary to identify and treat those traumatized patients who
require rapid assessment, resuscitation and stabilization of their injuries, as provision of
efficient trauma care both in hospital and pre hospital settings improves the chances of
survival and decreases permanent disability in trauma patients.
Objectives:
At the end of the session the student should be able to:
1. Rapidly and accurately assess trauma patient
2. Perform lifesaving measures
3. Prepare patient for transport within golden hour (hour after injury).
NEUROSURGERY
Head Injury and Management

Recognize different types of head injury.
Assess patients in emergency
Plan investigation of trauma patients.
951
Read x-rays of skull, cervical spine and CT scan of the head of trauma patients.
Manage the patients with head injury emergency.
Describe the long term management of head injury patients.
Decide which patients need investigation and observation.
Brain Tumors
Understand the basic classification of brain tumors, benign vs malignant, primary
vs secondary and on the basis of cells of origin.
Recognize the general clinical presentation of brain tumors.
Plan investigation of patients with brain tumor.
Read CT Scan and MRI of important brain tumors (Gliomas, meningiomas, acustic
neuromas, pituitary tumors and medastatis).
Recognize patients with raise intracranial pressure and Institute emergency
management.
Outline the principles of management of brain tumors.
Describe the principles of craniotomy.
Recognized the postoperative complications following craniotomy and decide
which patients need investigation and observation.
Cerebro Vascular Accidents
Recognize the different types of brain haemorrhages
Differentiate between subarachnoid and intracerebral hemorrhage
Understand the presentation of Subarachnoid Haemorrhage.
Enlist different causes of SAH
Diagnose SAH on the basis of presentation and order relevant investigations.
Manage patient medically.
Describe the surgical management of different causes of SAH.
Read the CT scan of SAH and intracerebral hemorrhage.
Describe the presentation of Hypertensive intracerebral hemorrhage
Describe the management of intracerebral hemorrhage.
Spinal Injury & Management
Recognize different types of spinal injury.

Assess patients of spinal injury in emergency
Administer emergency treatment of these patients including emergency
resuscitation,
Understand principles of immobilization, cervical collar, log-roll, traction and
fixation.
Plan investigation of trauma patients.
Read x-rays of cervical, thoracic and lumbar spine trauma patients.
Identify major spinal injuries on MRI of trauma patients.
Describe the long term management of spinal injury patients.
952
Describe the principles of physical rehabilitation.
Decide which patients need investigation and observation.
Degenerative Spinal Diseases

Understand the basic classification of brain tumors, benign vs malignant,
primary vs secondary and on the basis of cells of origin.
Recognize the general clinical presentation of brain tumors.
Plan investigation of patients with brain tumor.
Read CT Scan and MRI of important brain tumors (Gliomas, meningiomas,
acustic neuromas, pituitary tumors and medastatis).
Recognize patients with raise intracranial pressure and Institute emergency
management.
Outline the principles of management of brain tumors.
Describe the principles of craniotomy.
Recognized the post-operative complications following craniotomy and
decide which patients need investigation and observation.
Neurological Assessment
Record comprehensive history of patients with neurological symptoms.
Do a complete neurological examination in correct way.
Tailor neurological examination according to the history.
Localize the lesion and suggest the differential diagnosis.
Order relevant investigations.
Approach to Patient with Head Injury
Do primary survey and basic resuscitation ABC in a simulated patient.

Perform secondary survey.
Order relevant investigations blood investigation X-rays, CT Scans, MRI.
Initiate medical treatment to optimize the patient and for raise intracranial
pressure.
Understands principles of surgical management.
Describe the ICU care of head injury patients.
Reading Head CT Scan
Understand the principles of CT scanning.

Describe the normal CT scan head and brain.
Discuss the principles of mass effect and midline shift.
Differentiate between plain and contrast, soft tissue and bone windows
Read CT scan of major pathologies such is hydrocephalus, gliomas and
meningiomas and intracerebral hemorrhages and brain abscesses.
Identify different types of hematomas.
953
Reading MRI Head and Spine
Understand the principles of MRI scanning. T1, T2, FLAIR in contrast.

Describe the normal MRI scan head and brain and spine.
Differentiate between plain and contrast MRI.
Read MRI scan of major pathologies such is brain tumors, hydrocephalus,
cerebral infarctions, spinal injuries and cervical and lumbar disk herniation.
Approach to Patient with Spinal Injury
Do primary survey and basic resuscitation ABC in a simulated patient.

Perform secondary survey.
Order relevant investigations blood investigation X-rays, CT Scans, MRI.
Initiate medical treatment to optimize the patient.
Understands principles of surgical management.
Describe the ICU care of spinal injury patients.
ORTHOPEDICS
Basic Orthopedic Terminologies & Fracture Classification:
Student should be able to describe basic terminology used to define open and
closed fractures, dislocations and subluxations.
Discuss common fracture and joint injuries; identify specific problems with
their diagnosis.
History & Orthopedic Examination:
Demonstrate the ability to perform and appropriate orthopaedic history and

Demonstrate the ability to present and give a concise case history
presentation and discussion.
To be able to perform examination of Hip, Knee, Shoulder and Spine.
954
Radiological Interpretation:
Should be able to know how to read orthopaedic X-Rays and identify injury.
Should know role for ordering appropriate orthopaedic X-Ray (2 views, 2 Joint
etc).
Should know role of MRI, CT scan and Ultra Sound in Orthopaedic Practice.
Bone Tumor:
Able to take appropriate history and do physical examination of patients

presenting with musculoskeletal neoplasia.
Should be able to interpret radiological findings for suspected bone tumor.
Should be able to define describe and discuss diagnostic work up for a patient
with a suspected primary and secondary malignant neoplasm of bone.
Acute and chronic osteomyelitis
Enable to take history and differentiate both the problems

Learn about the mechanism and etiology of both problems
Haematological and Radiological interpretation and identify different points
between both the conditions
Enable to make a management plan for acute and chronic osteomyelitis
Upper limb trauma
General Assessment of trauma patient according to Advanced trauma

protocol
Perform appropriate examination in relation to particular fracture ie. Radial
and ulnar artery pulsation in supracondylar fracture , radial nerve assessment
in humerus fracture
Appropriately advise the radiographs
Enable to describe the emergency and definitive treatment of problem
Lower limb trauma

General patient Assessment according to Advanced trauma life support
Perform important neurovascular examination of lower limb
Describe the open wounds and grading
Enable to differentiate in the treatment between the open and close
fractures
Guidelines about the emergency back slab application
Identification of implant used in lower limb fractures
955
Metabolic bone disease
Enable to take history and categorically justify the different metabolic bone
disease
Enumerate the metabolic bone disease
Enable to perform clinical examination and identify the deformities
associated with the metabolic bone diseases
Advise basic investigations in relation to metabolic bone disease and able to
differetiate different metabolic problems from haematological and radiological
investigations
Describe the treatment of important metabolic bone problems
Congenital orthopaedic problems
Take history from parents about paediatricorthopaedic problems

Identify Talipesequinovarus foot deformity , and know the components
of deformity and able to describe the management plan of deformity
Enable to diagnose developmental dysplasia hip from history , clinical
examination and radiology. Describe the age dependent treatment of
DDH.
956
CREDIT HOURS OF SURGERY
13.5

957
EXAMINATION PATTERN FOR MBBS FINAL YEAR SEMESTER IX- X
Surgery & Allied
SEMESTER ASSESMENT:
This shall have:
958
WRITTEN EXAMINATION
Total Marks 400

Surgery will have two theory papers. the distribution of topics for Surgery Paper-I & Surgery
Paper-II is given below.

150MARKS
Twenty five questions in each paper will be based on photograph/ diagrams or

graphs. (Alternative to practical) to be graded with the clinical examination.
This component consist of Noninteractive Stations Viva and the marks
obtained will be counted toward clinical examination
50 MARKS
959
TOTAL 200 MARKS
The practical examinations in Surgery shall consist of total 10 stations.

History taking
Management
Counseling
X-rays and table vivas
Short case
Short case
Short case
TOTAL= 140 MARKS
based on the following subjects:
Neurosurgery
Orthopedics
Trauma
TOTAL= 60 MARKS
960
DISTRIBUTION OF TOPICS
SURGERY PAPER 1 DIVISION
S.No Topics
1. Metabolic Response to injury
2. Preoperative Preparations
3. Post-Operative Management
4. Care in the Operating Room
5. Perioperative Management in High Risk Patients
6. Anesthesia & Pain Relief
7. Fluid & Electrolyte & Acid Base Balance
8. Blood Transfusion & Shock
9. Thyroid / Parathyroid
10. Trauma / Disaster
11. Nutrition
12. Wound healing & tissue repair & Sear
13. Surgical infection
14. Principles of Pediatric Surgery
15. Orthopedics
16. Neurosurgery
17. Skin & Subcutaneous Tissue
18. Plastic Surgery & Burns, Reconstruction of cleft lip & palate
19. Breast
20. Arterial, Venous disorders & Lymphatic
961
SURGERY PAPER 2 DIVISION
S.No Topics
1. Thorax
2. Esophagus
3. Stomach & Duodenum
4. Liver
5. Gall & Bladder & Bile Ducts
6. Spleen
7. Pancreas
8. Peritoneum, Omentum& Mesentery
9. Disease of Small & large intestine
10. Intestinal obstruction
11. Appendix
12. Rectum
13. Perineal Conditions Anus & Anal Canal
14. Hernia & Umbilicus & Abdominal Wall
15. Kidney & Ureter
16. Urinary Bladder Urethra & Penis
17. Testicles & Scrotum
18. Prostate Gland
19. Transplantation & Oncology
962
ASSESMENT PLAN OF SEMESTER IX- X
PAPER 1 One best Questions 150
SCENARIO BASED 50
QUESTIONS (ATP)
PAPER 2
SCENARIO BASED 50
QUESTIONS (ATP)
INTERACTIVE 140
ASSESSMENT
NON-INTERACTIVE 60
STATIONS( TOTAL=3 )
963
MARKS ALLOCATION
Theory:
Total: 300 marks
component
Total: 300 marks
964
GYNECOLOGY
&
OBSTETRICS
965
GYNECOLOGY & OBSTETRICS
WEEK TOPIC 1 TOPIC 2 TOPIC 3 TOPIC 4
Gestational Ectopic Pregnancy

Amenorrhea Abnormal Uterine
1ST Trophoblastic
/PCOS Bleeding
WEEK Diseases
Vaginal Discharge &

2ND Miscarriage U.V. Prolapse Other Gynecology
Subfertility infections
WEEK
High Risk Ante-partum Preterm Labor,

RD
3 Antenatal Care
Pregnancy Hemorrhage
WEEK
Anemia in Multiple
4TH Post Term Labor
Pregnancy Pregnancy
WEEK
966
WEEK TOPIC 1 TOPIC 2
Maternal and Prenatal Mortality Fetal Surveillance

1ST WEEK
Normal Labor Abnormal Labor

2ND WEEK
Mal-presentation and Malposition Contraception

3RD WEEK
Minor + Major Surgical procedures Instruments of Obstetrics +

4TH WEEK
in Obstetrics + Gynecology Gynecology
967
MAIN LECTURES
NO. TOPIC
1. Ovarian Tumor
2. Subfertility/ ART
3. Prenatal diagnosis
4. Diabetes in pregnancy
5. Cardiac disease, hypertensive disease
6. liver disease in pregnancy
7. Urinary & fetal incontinence
8. Vulvar & vaginal tumors
9. Cervical tumors
LEARNING OBJECTIVES: GYNECOLOGY & OBSTETRICS
Amenorrhea
Define and classify amenorrhoea
Discuss common causes of primary and secondary amenorrhoea
Discuss pathogenesis of common causes of primary and secondary amenorrhoea
(including PCOS)
Discuss various clinical features relevant to diagnosis
Enumerate relevant important investigation for diagnosis
Discuss related health problems esp. with PCOS
Discuss management options including hormonal therapy.
968
Abnormal Uterine Bleeding
Definition and terminologist of abnormal uterine bleeding

Causes of AUB
Be able to take relevant history to reach a differential diagnosis
Order appropriate investigation
Be aware of medical and surgical options, their indications and contra-indication.
Gynecological Malignancies
Definitions.
Screening for gynae malignancies
Staging and grading
History, examination, investigation and management options for each
Complications and follow up.
Palliative care.
Maternal and Perinatal Mortality
Recall related definition

Recall recent statistics with special reference to local data
Describe causes with special reference to local data
Discuss various measures for prevention / reduction of maternal and perinatal
mortality.
Postpartum Hemorrhage
Evaluation and assessment of post-partum blood loss and its definition

Initiate emergency measure while awaiting seniors help
Send relevant investigations and arrangement of blood and blood products.
Know the major causes of post-partum hemorrhage tone tissue, trauma
thromboplastic
Help obstetrician in procedures
Antepartum Hemorrhage
Recognize causes of APH i.e. abruption, placenta praevia

Assess blood loss
969
Emergency resuscitative measure in patients bleeding heavily
Use diagnostic tools to confirm cause
Diagnosis, management and complications
Utero-Vaginal Prolapse(UVD)
Define UVP
Describe classification and types.
Discuss pathogenesis and risk factors
Discuss clinical features, along with complication
Enumerate and justify various relative investigation
Discuss various modes of management
Discuss post-operative care in patients with prolapse surgery and prognosis
Fetal Surveillance
Monitor fetus in antepartum period by

Maintaining partogram and understanding and interpretation of partogram.
Auscultate fetal heart sounds.
Perform and interpret routine CTG
In antenatal period student should be able to do a thorough abdominal examination
of the pregnant women.
Assess lie, presentation, SFH amount of liquor, engagement estimated fetal weight
and auscultate FHS.
Perform CTG and interpret finding.
Initial management of non-reassuring CTG.
Abnormal Labor / CPD
Definitions: Abnormal Labor and brief concept of FETO PELVIC disproportion

RISK FACTOR IDENTIFICATION: form history and examination
Complications: Maternal Fetal
Patterns of Abnormal Labor (i) Prolonged Phase (ii) Primary Dysfunctional (iii)
Secondary avert: Definition and time limits.
Identification of Abnormal Labor Patterns on Partogram, protraction and arrest
disorders. Time limits.
Patients reassessment in case of abnormality on partogram
Interventions (i) Hydration (ii) Oxytocin augmentation, method infusion and
monitoring of uterine contractors and fetal heart.
To determine need for operative delivery.
970
Early Pregnancy Disorders
Miscarriage
Ectopic Pregnancy
Gestational trophoblastic Disease
To diagnose intrauterine pregnancy, pregnancy of unknown location (PUL) & ectopic
pregnancy
To diagnose threatened , inevitable, incomplete & missed miscarriage
Resuscitation and ER management of inevitable and incomplete miscarriage preparation
for ERPC.
To diagnose acute and sub-acute pregnancy : History, Examination, investigation
To diagnose molar pregnancy from history, examination and investigations.
Counseling of patient with molar pregnancy
Multiple Pregnancies
To identify risk factors for multiple pregnancy form patients history and examination.
To diagnose multiple pregnancy.
To identify maternal and fetal complication of multiple pregnancy esp. anemia
hypertensive disorders antepartum,
To identify complications of monochromic pregnancy i.e. fetal growth restriction,
Twin to Twin transfusion syndrome.
To determine fetal presentation of leading twin.
To monitor Twin pregnancy (uncomplicated) in labour.
To be able to assist vaginal delivery of leading cephalic twin pregnancy.
To prevent postpartum hemorrhage in twin delivery.
Contraception
To define contraception with the classification of various contraceptive methods.

To describe the formulations, indications, benefits, side effect and contraindications
of different contraceptive methods.
To describe the method of emergency contraception.
To understand the permanent methods of contraception i.e. sterilization and
vasectomy.
Medical Disorders in Pregnancy
971
To define and classify hypertensive disorders of pregnancy
Risk factors for developing pre-eclampsia and eclampsia
Feto-maternal complication of hypertensive disorders
Evaluation and management of PIH, Pre-Eclampsia and eclampsia
Different anti-hypertensive agents their doses side-effects.
Magnesium sulphate protocol and monitoring of patients on Magnesium sulphate
therapy.
Definition of diabetes in pregnancy.
Maternal and fetal complication of diabetes
Factors associated with poor fetal outcome in diabetes.
Management of diabetes in pregnancy i.e. antenatal and post-partum.
Definition of anemia in pregnancy
To describe classification of anemia in pregnancy
Feto-maternal complication of iron deficiency anemia
Management of anemia in pregnancy i.e. oral and parenteral therapy and indications
of blood transfusions.
Normal Labor and its Management
To define normal labour

To describe three stages of labour
To understand the mechanism of normal labour
History taking examination and evaluation of laboring patients
To monitor progress of labour by maintaining partogram
To understand what to plot and interpretpartogram
Management of three stages of labour
Analgesia and anesthesia in labour
To observe and assist the conduct of normal vaginal delivery.
To observe the repair of epsiotomy
To observe the immediate care and resuscitation of newborn.
Preterm and Post-term Labor
To define preterm labour

To understand etiology and risk factors for preterm labour
To identify the clinical features of preterm labour
To know the investigations with interpretation regarding preterm labour.
Management of preterm labour with tocolytics, maternal steroids and antibiotics.
To define postdated and post term pregnancies
972
Complications of post term pregnancy
To understand the various methods of induction of labour i.e. prostaglandins and
amniotomy.
EMERGENCY LIFE SAVING SKILLS: GYNECOLOGY & OBSTETRICS
Title of skill: NEONATAL RESUSCIATION
Introduction:
Management of newborn immediately after birth is an essential skill as 10% of all babies
require some resuscitation and 1% requires extensive resuscitation.
Describe protocol for neonatal resuscitation
Demonstrate correct technique of technique of bag and mask ventilation and chest
compressions in neonate.
List drugs used in neonatal resuscitation
Title of skill: Management of Postpartum Hemorrhage
Introduction:Active management of the third stage of labor significantly decreases the risk of
postpartum hemorrhage. It involves the use of oxytocic medication, immediate cord
clamping and delivery of the placenta by controlled cord traction. Practitioners need to be
aware of the risk factors for postpartum hemorrhage. Women at risk should deliver in units
where specialist assistance, operating facilities, and blood and blood products are available.
Describe risk factors associated with postpartum hemorrhage
Describe protocol for managing postpartum hemorrhage
973
CREDIT HOURS OF
4.5

974
SEMESTER IX- X

SEMESTER ASSESMENT:
This shall have:
975
WRITTEN EXAMINATION
Total Marks 400

There shall be two theory papers, one each for Gynecology and Obstetrics.

150MARKS
Twenty five questions in each paper will be based on photograph/ diagrams or

graphs. (Alternative to practical) to be graded with the clinical examination.
This component consist of Noninteractive Stations Viva and the marks
obtained will be counted toward clinical examination
50 MARKS
976
TOTAL 200 MARKS
The practical examinations in Gynecology & Obstetrics shall consist of total 10 stations.
Obstetrics History
Gynae History
Obstetrics Examination
Obstetrics Procedure
Gynae Procedure
Counseling
Interpretation of reports/ graphs
TOTAL= 140 MARKS
TOTAL= 60 MARKS
GYNECOLOGY & OBSTETRICS PAPERS DIVISION
Paper 1 GYNECOLOGY
Paper 2 OBSTETRICS
977
ASSESMENT PLAN OF SEMESTER IX- X
ASSESSMENT TOOLS MARKS
PAPER 1
SCENARIO BASED
50
QUESTIONS (ATP)
PAPER 2
SCENARIO BASED
50
QUESTIONS (ATP)
INTERACTIVE
140
STATIONS(TOTAL =7)
CLINICAL
ASSESSMENT NON-INTERACTIVE
60
STATIONS( TOTAL=3 )
978
MARKS ALLOCATION
Theory:
Gynecology: 150 marks to be assessed in written paper BCQ component
Obstetrics: 150 marks to be assessed in written paper BCQ component
Total: 300 marks
component
Total: 300 marks
979
Section 3
980
CONSOLIDATE
D TRANSCRIPTS
981
Marks obtained in
GPA Grade
Percentage Range
80-100 4.0 A+
75-79
70-74
4.0
3.7
A
A-
67-69 3.3 B+
63-66 3.0 B
60-62 2.7 B-
56-59 2.3 C+
50-55 2.0 C
0-49 0.0 F
Absent 0.0 Abs
CONSOLIDATED MODULAR TRANSCRIPT

Enrollment No:
Candidates Name:
Fathers Name:
Institute:
Credit
Foundation Spiral Description Grade Grades Points
Hours
Module I Foundation Module Theory 6.00
I Foundation Module Viva 3.00
Hematology I Hematology Module-I Theory 6.00

I Hematology Module-I Viva 3.00
Module
II Hematology Module-II Theory 3.00
II Hematology Module-II Viva 1.50
I Locomotors Module Theory 6.00

Locomotor Module I Locomotors Module Viva 3.00
I Respiratory I Module Theory 3.00

Respiratory I Respiratory I Module Viva 1.50
Module II Respiratory II Module Theory 3.00
II Respiratory II Module Viva 1.50
Cardiovascular I Module
Cardiovascular I Theory 3.00
Module I Cardiovascular I Module Viva 1.50
Cardiovascular II Module
II Theory 3.00
II Cardiovascular II Module Viva 1.50
I Neurosciences Module-I Theory 6.00

Neurosciences Module I Neurosciences Module-I Viva 3.00
II Neurosciences II Module Theory 6.00
II Neurosciences II Module Viva 3.00

I Module Theory 3.00
I Head & Neck and Special Senses 1.50
982
Module Viva
Head & Neck and
Special Senses Module
Endocrinology I Endocrinology I Module Theory 3.00
Module I Endocrinology I Module Viva 1.50
II Endocrinology II Module Theory 3.00
II Endocrinology II Module Viva 1.50

I GIT & Liver I Module Theory 6.00
GIT & Liver
Module I GIT & Liver I Module Viva 3.00
II GIT & Liver II Module Theory 6.00
II GIT & Liver II Module Viva 3.00

I Renal I Module Theory 3.00
Renal Module
I Renal I Module Viva 1.50
II Renal II Module Theory 3.00

I Reproductive I Module Theory 3.00
Reproductive II Renal II Module Viva 1.50
Module I Reproductive I Module Viva 1.50
II Reproduction Module II Theory 5.00
Infectious II
II Reproduction
Infectious Module
Diseases II Viva
Module Theory 2.50
3.00
Diseases Module
II Infectious Diseases Module Viva 1.50
II Eye Module Theory 3.00

Ophthalmology
II Eye Module Viva 1.50
Module
ENT Module II ENT Module Theory 3.00
II ENT Module Viva 1.50
Musculoskeletal II Musculoskeletal Module Theory 4.00
Module II Musculoskeletal Module Viva 2.00
Rehab Medicine Rehab Medicine Dermatology

Dermatology II Genetics Module Theory 3.00
Genetics Rehab Medicine Dermatology

II Genetics Module Viva 1.50
III MEDICINE 13.5

SEMESTER- IX
III PEDIATRICS 4.5
X
III SURGERY 13.5

SEMESTER- IX -X
III GYNAECOLOGY & OBSTRICS 4.5
Total Credit
Hours 180
983
KEY:
1. Spiral I consists of Basic Sciences Component
2. Spiral II consists of Clinical Sciences Component
3. Spiral III consists of Supervised Practical Training
Undergraduate Career Total:

Term CGPA:
The above marks include
20% weightage of Module Examination
80% weightage Semester Examination
Credit Hours of each paper is the total amount of teaching of that module that this paper
assesses. A credit hour means teaching a theory course for 50 minutes each week throughout
the semester. One credit hour in laboratory or practical work / project would require lab
contact of two hours per week throughout the semester.
Grade Points Average (GPA) of each paper correspond to the marks obtained in percentage
range in each paper as given in the table at the upper left hand corner of page one of the
transcript.
Grades correspond to the GPA as given in the table at the upper left hand corner of page one
of the transcript.
Grade Points are calculated by multiplying the Grade Point Average (GPA) with credit hours.
Term GPA (Term Grade Points Average) calculated by dividing the total grade points of the
term or semester by the total credit hours of the term or semester.
cGPA (Cumulative Grade Points Average) calculated by dividing the total grade points of all
courses of the program with the total credit hours of the program.
Dated:
Checked by Controller of Examinations
Note: Should any error in transcript be made inadvertently, the university reserves the right to correct the
same.
984
Marks obtained in
GPA Grade
Percentage Range
80-100 4.0 A+
75-79
70-74
4.0
3.7
A
A-
67-69 3.3 B+
63-66 3.0 B
60-62 2.7 B-
56-59 2.3 C+
50-55 2.0 C
0-49 0.0 F
Absent 0.0 Abs
CONSOLIDATED SEMESTER TRANSCRIPT

Enrollment No:
Candidates Name:
Fathers Name:
Institute:
Semester-I
Course Code Description Credit Grade Grades Points
Hours
101 Foundation Module Theory 6.00
101 Foundation Module Viva 3.00
101 Hematology I Module Theory 6.00
101 Hematology I Module Viva 3.00
SEMESTER- II
102 Locomotor Module Theory 6.00
102 Locomotor Module Viva 3.00
102 Respiratory I Module Theory 3.00
102 Respiratory I Module Viva 1.50
102 Cardiovascular I Module Theory 3.00
102 Cardiovascular I Module Viva 1.50
SEMESTER- III
201 Neurosciences I Module Theory 6.00
201 Neurosciences I Module Viva 3.00
201 Head & Neck and Special Senses Module 3.00
Theory
201 Head & Neck and Special Senses Module Viva 1.50
201 Endocrinology I Module Theory 3.00
201 Endocrinology I Module Viva 1.50
SEMESTER- IV
202 GIT & Liver I Module Theory 6.00
202 GIT & Liver I Module Viva 3.00
202 Renal I Module Theory 3.00
202 Renal I Module Viva 1.50
202 Reproductive Module-I Theory 3.00
202 Reproductive Module-I Viva 1.50
985
SEMESTER- V
301 Infectious Diseases Module Theory 3.00
301 Infectious Diseases Module Viva 1.50
301 Respiratory II Module Theory 3.00
301 Respiratory II Module Viva 1.50
301 Hematology II Module Theory 3.00
301 Hematology II Module Viva 1.50
301 Cardiovascular II Module Theory 3.00
301 Cardiovascular II Module Viva 1.50
SEMESTER- VI
302 GIT & Liver II Module Theory 6.00
302 GIT & Liver II Module Viva 3.00
302 Endocrinology II Module Theory 3.00
302 Endocrinology II Module Viva 1.50
302 Renal II Module Theory 3.00
302 Renal II Module Viva 1.50
SEMESTER- VII
401 Eye / ENT Module Theory 3.00
401 Eye / ENT Module Viva 1.50
401 Musculoskeletal Module Theory 4.00
401 Musculoskeletal Module Viva 2.00
401 Reproduction II Module Theory 5.00
401 Reproduction II Module Viva 2.50
SEMESTER- VIII
402 Eye / ENT Module Theory 3.00
402 Eye / ENT Module Viva 1.50
402 Neurosciences II Module Theory 6.00
402 Neurosciences II Module Viva 3.00
402 Dermatology, Rehabilitation & Genetics 3.00
Modules theory
402 Dermatology, Rehabilitation & Genetics 1.50
Modules theory
SEMESTER- IX -X
500 MEDICINE 13.5
500 PEADS 4.5
SEMESTER- IX -X
500 SURGERY 13.5
500 GYNAE & OBS 4.5
Total Credit Hours 180
986
Undergraduate Career Total:
Term CGPA:
The above marks include

20% weightage of Module Examination
80% weightage Semester Examination
Credit Hours of each paper is the total amount of teaching of that module that this paper
assesses. A credit hour means teaching a theory course for 50 minutes each week throughout
the semester. One credit hour in laboratory or practical work / project would require lab
contact of two hours per week throughout the semester.
Grade Points Average (GPA) of each paper correspond to the marks obtained in percentage
range in each paper as given in the table at the upper left hand corner of page one of the
transcript.
Grades correspond to the GPA as given in the table at the upper left hand corner of page one
of the transcript.
Grade Points are calculated by multiplying the Grade Point Average (GPA) with credit hours.
Term GPA (Term Grade Points Average) calculated by dividing the total grade points of the
term or semester by the total credit hours of the term or semester.
cGPA (Cumulative Grade Points Average) calculated by dividing the total grade points of all
courses of the program with the total credit hours of the program.
Dated:
Checked by Controller of Examinations
Note: Should any error in transcript be made inadvertently, the university reserves the right to correct the
same.
987
RECOMMENDE
D BOOKS
988
RECOMMENDED BOOKS
Following is the list of books recommended by the faculty of the respective subject.
Students are encouraged to access additional sources of information to enhance their
knowledge of the subjects.
ANATOMY
CLINICALLY ORIENTED ANATOMY
KEITH.L.MOORE, Arthur F. Dalley, Anne M.R. Agur
7th or Latest EDITION
GRAY'S ANATOMY FOR STUDENTS

Drake & Vogl & Mitchell
3rd or Latest EDITION
CLINICAL ANATOMY BY REGIONS

Richard S. SNELL
9th EDITION
LASTS ANATOMY: REGIONAL & APPLIED

Chummy S. Sinnatamby
ATLAS OF HUMAN ANATOMY

FRANK H.NETTER
6th EDITION
EMBRYOLOGY
THE DEVELOPING HUMAN CLINICALLY ORIENTED EMBRYOLOGY
MOORE & PERSAUD & TORCHIA
10th EDITION
LANGMANS MEDICAL EMBRYOLOGY

T.W.SADLER
13th EDITION
HISTOLOGY
MEDICAL HISTOLOGY
LAIQ HUSSAIN SIDDIQUI
5TH or Latest EDITION
989
BASIC HISTOLOGY( TEXT AND ATLAS)
LUIZ JUNQUEIRA, JOSE CARNEIRO
PHYSIOLOGY
GUYTON AND HALL TEXTBOOK OF MEDICAL PHYSIOLOGY

GUYTON AND HALL
13th EDITION
BIOCHEMISTRY
LIPPINCOTTS ILLUSTRATED REVIEWS SERIES
DENISE R. FERRIER
6th EDITION
HARPERS ILLUSTRATED BIOCHEMISTRY

VICTOR RODWELL, DAVID BENDER, KATHLEEN M. BOTHAM, PETER J. KENNELLY,
P. ANTHONY WEIL
28th EDITION
BASIC PATHOLOGY
PATHOLOGY
ROBBINS BASIC PATHOLOGY
KUMAR & ABBAS
9TH EDITION
ROBBINS & COTRAN PATHOLOGIC BASIS OF DISEASE

KUMAR & ABBAS & ASTER
9th EDITION
COMMUNITY MEDICINE
PUBLIC HEALTH AND COMMUNITY MEDICINE

SHAH, ILYAS, ANSARI
7th EDITION
PHARMACOLOGY
990
LIPPINCOTTS ILLUSTRATED REVIEW PHARMACOLOGY
Karen Whalen
th
6 or Latest Edition
BASIC AND CLINICAL PHARMACOLOGY

BERTRAM G. KATZUNG
11th EDITION
FORENSIC MEDICINE
PRINCIPLES AND PRACTICE OF FORENSIC MEDICINE

Nasib R.Awan
1st EDITION
MEDICINE & MEDICAL SPECIALTIES
PRINCIPLES & PRACTICE OF MEDICINE

DAVIDSONS
nd
22 or Latest Edition
ESSENTIALS OF KUMAR AND CLARK'S CLINICAL MEDICINE

KUMAR & CLARK
th
9 or Latest Edition
MACLEOD'S CLINICAL EXAMINATION

DOUGLAS & NICOL & ROBERTSON
13TH or Latest Edition
HUTCHISON'S CLINICAL METHODS

WILLIAM M DRAKE & MICHAEL GLYNN
23rd or Latest Edition
RAPID INTERPRETATION OF EKGS

DALE-DUBIN
th
6 or latest Edition
991
PEDIATRICS
NELSONSS ESSENTIALS OF PEDIATRICS

MARCDANTE & KLIEGMAN
7th or Latest Edition
SURGERY & SURGICAL SPECIALTIES
SHORT PRACTICE OF SURGERY

ROBERT JOHN MCNEILL LOVE, HENRY HAMILTON BAILEY
26TH EDITION or Latest Edition
Current Diagnosis and Treatment Surgery

GERARD M.DOHERTY
BROWSE'S INTRODUCTION TO THE SYMPTOMS & SIGNS OF SURGICAL

DISEASE
NORMAN L BROWSE
th
5 or Latest Edition
GYNECOLOGY BY TEN TEACHERS

TEN TEACHERS
19th or latest Edition
PRINCIPLES OF GYNECOLOGY
JEFFCOATES
TH
7 or Latest Edition
OBSTETRICS BY TEN TEACHERS
TEN TEACHERS
th
19 or latest Edition
Fundamentals of Obstetrics and Gynecology

DEREK LLEWELLYN-JONES
992
REVIEW
STRATEGIES
993
STRATEGIES FOR MONITORING AND IMPROVEMENT
Continuous review and reevaluation of the curriculum is required in order to

keep it aligned with the needs of the end users, the students and the faculty,
and the ultimate beneficiary, the community. The curriculum also needs to be
updated in accordance with the latest advances and evidence based current
practices, world wide. For this, feed back is taken by the Quality Enhancement
Cell (QEC) of the University. Feedback taken from the students regarding the
contents and delivery of individual lectures. (Form-1). Feedback is also taken
from the students and faculty about the implementation of the modules on HEC
prescribed proformas (Forms-2,3). Finally the teachers evaluation is provided
by the students on HEC prescribed proforma (Form-4). Recommendations are
generated from the analyses of these feedbacks by the QEC and these
recommendation are communicated to the Curriculum Committee and the
respective module committees for incorporation of changes in reviewed
documents. Students feedback of individual lectures and teachers is also
communicated to the respective faculty members for necessary improvement.
994
FORM-1
STUDENT FEEDBACK FORM
Lecture Feedback.
Lecture Title : _________________________________Presenter: _______________________
1 2 3 4 5
Strongly Disagree Disagree Neutral Agree Strongly Agree
Please circle the most appropriate;
Variable
Lecture contents are according to learning objectives 1 2 3 4 5
Delivery of lecture by the presenter was clearly 1 2 3 4 5
understandable
Quality of slides were good 1 2 3 4 5
Comments / Remarks (optional)
Thank you for your feedback
995
FORM-2
STUDENT FEEDBACK FORM
Module Feedback.
MODULE
Date of implementation
Date of submission: ___________________
Name: ________________________________
Roll no. ___________________________
The Curriculum Committee of DUHS requests your feedback regarding the recently
implemented above mentioned module in order to assist it to improve the quality of teaching.
A B C D E
1. Module Objectives were clearly defined:
2. Learning Objectives aligned with contents:
3. Course Contents adequately represented:
4. Time Allocated to Each Topic satisfactory:
5. Quality of Teaching Material was good:
6. Terminal objectives achieved :
7. Overall impression of students interest
was good:
A. Strongly Agree B. Agree C. Unsure D. Disagree E. Strongly

Disagree
996
FORM-3
Faculty Feedback Form

Module
Date of implementation
Date of submission: ___________________
Name: ________________________________
Designation: ___________________________
Department: ___________________________
The Curriculum Committee of DUHS requests your feedback regarding the recently implemented
above mentioned module in order to assist it to improve the quality of teaching.
A B C D E
8. Module Objectives were clearly defined:
9. Learning Objectives were aligned with contents:
10. Course Contents adequately represented:
11. Time Allocated to Each Topic satisfactory:
12. Quality of Teaching Material was good:
13. Terminal objectives achieved :
14. Overall impression of students intrest was good:
B. Strongly Agree B. Agree C. Unsure D. Disagree E. Strongly

Disagree
997
FORM-4
Teacher Evaluation Form
(To be filled by the student)
Module Title and Number: ____________________________________________
Name of Instructor: ________________________Semester___________________
Department: _________________________________________________________
Use the scale to answer the following questions below and make comments
A: Strongly Agree B: Agree C: Uncertain D: Disagree E: Strongly Disagree
S.No. Instructor:
1. The Instructor is prepared for each class A B C D E

2. The Instructor demonstrates knowledge of the subject A B C D E
3. The Instructor has completed the whole course A B C D E
4. The Instructor provides additional material apart from the textbook A B C D E
5. The Instructor gives citations regarding current situations with reference to Pakistani A B C D E
context.
6. The Instructor communicates the subject matter effectively A B C D E
7. The Instructor shows respect towards students and encourages class participation A B C D E
8. The Instructor maintains an environment that is conducive to learning A B C D E
9. The Instructor arrives on time A B C D E
10. The Instructor leaves on time A B C D E
11. The Instructor is fair in examination A B C D E
12. The Instructor returns the graded scripts etc. in a reasonable amount of time A B C D E
The Instructor was available during the specified office hours and for after class A B C D E
13. consultations
14. The Subject matter presented in the course has increased your knowledge of the A B C D E
subject
The syllabus clearly states course objectives requirements, procedures and grading A B C D E
15.
criteria
16. The course integrates theoretical course concepts with real-world applications A B C D E
17. The assignments and exams covered the materials presented in the course A B C D E
18. The course material is modern and updated A B C D E
Comments:
Instructor:___________________________________________________________________________
___________________________________________________________________________________
__________________________________________________________________________
Course:_____________________________________________________________________________
___________________________________________________________________________________
____________________________________________________________________________
998
welcomes feedback and suggestions for
improvement of the Curriculum.
Recommendations may kindly be forwarded to:
Curriculum Review Committee

c/o The Registrar,
Baba - e -Urdu Road Karachi
Email: curriculum@duhs.edu.pk
999

Final Module Book-20160514

Diunggah oleh

Informasi Dokumen

Hak Cipta

Format Tersedia

Bagikan dokumen Ini

Bagikan atau Tanam Dokumen

Opsi Berbagi

Apakah menurut Anda dokumen ini bermanfaat?

Apakah konten ini tidak pantas?

Hak Cipta:

Format Tersedia

Final Module Book-20160514

Diunggah oleh

Hak Cipta:

Format Tersedia

Dow University of Health Sciences

Integrated Modular Medical Curriculum

Integrated Modular Medical Curriculum

Integrated Modular Medical Curriculum

Edited and compiled by:

The University is also thankful to

Prof. Salahuddin Afsar, Dean Faculty of Medicine, Pro Vice

Prof. Junaid Ashraf, Professor of Neurosurgery, Principal

Prof. Khalid Mahmood, Chairperson Department of

Prof. Shams Nadeem Alam Professor of Surgery, DUHS

Prof. Abdul Rauf Memon Professor of Medicine, DUHS

Prof. Rukhsana Rubeen, Professor of Biochemistry, DUHS and

Prof. Naheed Khan, Professor of Anatomy, DUHS,

12. Dr. Sabahat Zaidi

Integrated Modular Medical

Prof. Masood Hameed Khan

Practice of medicine is a life-long process for a doctor and consequently learning is a

No transformation is possible without the involvement of a dedicated faculty and staff,

These curricular reforms were implemented simultaneously in all three constituent

Upon the recommendation of this committee the University approached the

On the initiative of Dow University of Health Sciences, in 2008, PMDC assigned

The examination system was also modified. Instead of an annual system of

The quality enhancement cell of DUHS evaluates the system by collecting

Professor Salahuddin Afsar

i. Semester Title with Modules in the Semester,

Integrated Modular Medical Curriculum

The three spirals:

1. Spiral -1 Basic Sciences spiral

(BASIC SCIENCES) SPIRAL FIRST TO FOURTH SEMESTER

(CLINICAL SCIENCES) SPIRAL FIFTH TO EIGHT SEMESTER

Scenario Based Learning (SBL)

Student Research Studies

(INTEGRATED SUPERVISED PRACTICAL TRAINING)

This Curriculum Document has been prepared in accordance to the

It is divided in three sections.

The second section is divided into Semester subsections. Each

While preparing the document of the module special consideration

Following are the subsection of each module document.

3. The Rationale of that module in the five year curriculum

5. The Learning Objectives of the Module are given in a tabular

6. Time Table the modes of transfer of information is organized in

7. Learning Objectives of the Lectures along with their codes is

LEARNING OBJECTIVE OF LECTURES

AT THE END OF THE LECTURE THE STUDENT SHOULD BE ABLE TO

EMBRYOLOGICAL DEVELOPMENT OF BLOOD ELEMENTS.

8. The Table of Specification is prepared by calculating the

WEEK 1st 2nd 3rd 4th 5th 6th Round of

EMBR 1.75 - - - - - 1.75 1.22

HISTO 1.50 - - - 4 1.75 7.25 5.08

PHYSIO 7 6.25 5 1.75 2 1.75 23.75 16.66

PATHO 4.50 4 7.25 5.25 2 9.75 32.75 22.98

MICRO 3.25 7 2.75 2.75 7 - 22.75 15.96

COM.MED 2.50 1.50 1 1 - 1.50 7.50 5.26

BEH.SCI 1 - 1.50 1 - 1 4.50 3.15

RES.METH 1.50 1.75 - - - - 3.25 2.28

SKILLS 1.50 - 1.75 1.75 1.50 - 6.50 4.56

Proportionate weightage to be given to each subject in written and oral examinations.

9. Blueprint of Assessment of the module is given in the next

ASSESMENT TOOLS MARKS WEIGHTAGE

The Final year (Semester IX and X) subsection provides these details

The third section contains subsections which are common to all

1. The Consolidated Transcript of the five years assessment is

2. The list of some of the recommended books. However the

(1 semester=16 weeks, 1 lecture of 50 minutes / week x 16 = 1 credit hour).

Posted from ______ to _ for _________ days