2. According to USP, the coarse powder is defined as which can pass 50% through the sieve no. of:
a) Greater than 1000 b) 355-1000 c) 180-355 d) 125-180
5. A powder has true volume of 20 ml and bulk volume was found to be 25 ml. What will be its predicted flow
property?
a) Free flow b) Good flow c) Fair flow d) Poor flow
6. For the good flow of a powder its angle of repose should be:
a) Less than 30 b) 30 to 40 c) 40 to 50 d) Greater than 50
9. Du Nouy ring method used for the calculation of surface tension of liquid employs a ring which is made up of:
10. Difference between the potential between the actual surface and the neutral region in a solid liquid interface is
defined as:
a) Zeta potential b) Nernst Potential c) Both d) None of the given
11. For perfect wetting of a solid surface, the contact angle of the wetting liquid with solid surface should be:
a) 0 b) 10-90 c) 90-180 d) 180
14. Volhards method for the endpoint detection in the precipitation titrations is mainly used for the:
a) Acidic solution b) Basic solutions c) Neutral solutions d) all solutions
15. Which of the following can be used as an indicator in the Fajans method of end point detection in the precipitation
titrations?
a) Eosin b) Flourscein c) None of the above d) Both
16. Which of the following method employed back titration for the determination of end point in precipitation
titrations?
a) Fajans Method b) Volhards method c) Mohrs method d) None of the above
17. Which of the following method employed the principal of adsorption for the determination of end point in
precipitation titrations?
a) Fajans Method b) Volhards method c) Mohrs method d) None of the above
18. End point determination in the Mohrs method is done by the help of following indicator:
a) Eosin b) Flourscein c) Chromate d) Permagnate
21. The short acting local anaesthetic among the following is:
a) Procaine b) Lidocaine c) Cocaine d) Benzocaine
22. The main mechanism of action through which local anaesthetics act is:
a) Ca channel blockers b) Na Channel blockers c) K Channel opener d) Chloride channel blocker
24. When an external magnetic field is applied, what happens to the protons in a sample?
a) All protons align with the field.
b) All protons align opposite to the field.
c) Some protons align with the field and some align opposite to it.
d) All protons assume a random orientation
27. Why is dopamine not the drug of choice for symptomatic treatment of Parkinson s Disease
when the symptoms of Parkinsons disease are caused by loss of dopamine
a) Dopamine cannot cross the blood brain barrier
b) Dopamine has serious side effects
c) Dopamine is less tolerated
d) All of the above
28. Which of the following compounds has the MOST deshielded protons?
a) CH3Cl
b) CH3I
c) CH3Br
d) CH4
29. Levodopa is used along with Carbidopa in the treatment of ParkinsonDisease because
Carbidopa
a) Aids Levodopa to cross blood brain barrier
b) Blocks the early conversion of Levodopa into dopamine
c) Enhances the absorption of levodopa
d) All of the above
30. Which of the following compounds is used as the refrence copmpound in the PMR
spectroscopy?
a) Tetramethylsilane
b) methyl fluoride
c) methanol
d) Methyl amine
32. Which of the following can be used as solvent in the PMR spectroscopy?
a) Carbon Tetrachloride
b) Chloroform
c) Butanol
d) Ethanol
34. Which of the following reaction undergoes through free radical mechanism?
a) Chlorination of methane in the presence of light
b) Addition of HBr to alkene
c) Reaction of alcohol in the presence of an acid
d) Addition of HCl to alkyne
39. Arrange the following compounds in order of decreasing chemical shift for the underlined
hydrogens (largest value first, smallest value last).
CH3CH2CHCH 3 3OCH2CH Cl3 2CHCH2CHClCH3 2CH2CH3
a b c d
a) b > c > a > d
b) b > c > d > a
c) c > b > a > d
d) c > b > d > a
43. The electrophilic substitution reactions occurring at indole occurs most predominantly at :
b) C-2 b) C-3 c) C-4 d) C-5
44. Which of the following heterocyclic compounds will readily undergo Diels-Alder reaction?
a) Furan b) Thiophene c) Benzene d) Pyrrole
45. Which of the following compounds has the MOST deshielded protons?
a) CH3F
b) CH3Cl
c) CH3OH
d) CH4
46. The time dependent viscosity change is observed in some fluids. In one such case, Gel-Sol-Gel transformation
is observed. This phenomenon popularly known as:
a) Rheopexy b) Negative Thixotropy c) Thixotropy d) Bingham bodies
49. The fluid in which viscosity increases with increase in rate of shear is considered as:
a) Plastic flow b) Dilatant flow c) Pseudoplastic flow d) Newtonian flow
52. Platelet aggregation is mainly achieved by the activation of which of the following?
a) TXA2 b) PGI2 c) PGE2 d) PGA2
55. The hepatotoxic metabolite produced due to the metabolism of paracetamol is:
a) N-accetyl-benzoquinone
b) N-cysteine-benzoquinone
c) N-tyrosine-benzoquinone
d) N-methyl-benzoquinone
56. Which of the following drugs is inhibited by the Accetyl salicylic acid in the body
a) Thiazide b) Methotrexate c) Phenytoin d) Warfarin
59. Which of the following NSAIDs exert its mechanism of action mainly through inhibiting release of cytokines
from WBC?
Phenylbutazone b) Sulindac c) nabumetone d) Nimesulide
1 a) 2 a) 3 a) 4 a) 5 d) 6 a) 7 c) 8 a) 9 b) 10 b) 11 a) 12 a) 13 c) 14 a) 15 c) 16 b) 17 a) 18 c) 19 b) 20 a)
21 a) 22 b) 23 b) 24 c) 25 c) 26 c) 27 d) 28 a) 29 d) 30 a) 31 d) 32 a) 33 a) 34 a0 35 c) 36 b) 37 d) 38 b) 39 b) 40
a)
41 b) 42 a) 43 b) 44 a) 45 a) 46 c) 47 d) 48 b) 49 b) 50 c) 51 a) 52 a) 53 d) 54 c) 55 a) 56 57 a) 58 a) 59 d)