LEMBAR PENGESAHAN

Yang bertanda tangan di bawah ini menyatakan bahwa:

Nama : Muh. Ridho Akbar

NIM : C111 12 065

Telah menyelesaikan tugas referat di Bagian Obstetri dan Ginekologi Fakultas

Kedokteran Universitas Hasanuddin Makassar

Makassar, November 2017

Konsulen Pembimbing

dr. Johnsen Mailoa, Sp. OG(K) dr. Stefanus Wibisono

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 DAFTAR ISI

LEMBAR PENGESAHAN ........................................................................... i

DAFTAR ISI .................................................................................................. ii
BAB I PENDAHULUAN ............................................................................. 1
BAB II TINJAUAN PUSTAKA ................................................................... 3
A. DEFINISI ................................................................................................ 3
B. EPIDEMIOLOGI .................................................................................... 3
C. ETIOLOGI ............................................................................................. 4
D. PATOGENESIS PENYAKIT MALARIA ............................................. 7
1. Siklus Hidup Seksual Plasmodium ..................................................... 7
2. Siklus Hidup Aseksual Plasmodium ................................................... 7
E. RESPON IMUN TERHADAP INFEKSI MALARIA ........................... 9
F. MALARIA DALAM KEHAMILAN ..................................................... 10
1. Pengaruh pada Ibu .............................................................................. 10
2. Pengaruh pada Janin ........................................................................... 11
G. IMUNITAS WANITA HAMIL YANG TERNFEKSI MALARIA ....... 12
H. HISTOPATOLOGI ................................................................................. 13
I. GAMBARAN KLINIS ........................................................................... 14
J. DIAGNOSIS MALARIA PADA KEHAMILAN .................................. 15
1. Anamnesis dan Pemeriksaan Fisis ..................................................... 15
2. Pemeriksaan Laboratorium ................................................................ 17
K. KOMPLIKASI MALARIA DALAM KEHAMILAN ........................... 19
1. Anemia ............................................................................................... 19
2. Hipoglikemia ...................................................................................... 20

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 3. Edema Paru Akut ............................................................................... 20
4. Imunosupresi ...................................................................................... 21
5. Gagal Ginjal ....................................................................................... 21
6. Risiko terhadap Janin ......................................................................... 21
7. Malaria Kongenital ............................................................................. 22
L. PENANGANAN MALARIA SELAMA KEHAMILAN ...................... 22
1. Pencegahan Transmisi ........................................................................ 22
2. Terapi Malaria .................................................................................... 24
3. Penanganan Komplikasi Malaria ....................................................... 34
4. Penanganan saat Persalinan ................................................................ 35
BAB III. KESIMPULAN ............................................................................... 37
DAFTAR PUSTAKA .................................................................................... 38

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