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Food Therapy: Beet or Beet Root, The Best in Ameliorated

Oxidative Stress

Kyle J. Norton

Beet may have a potential effect as antioxidants in reduced free radical and
oxidative stress expression through its chemical constituents, some scientists
suggested

Antioxidants are the set of substances with inhibited oxidative function

Beet, best known as the beetroot or garden beet and belonging to the amaranth
family, is a perennial plant with leafy stems growing to 12 m tall.

According to the joint study lead by the Istanbul Technical University, fresh red
beetroot and beet roots products contain several major antioxidants with
efficacy different, depending to total antioxidant capacities (TAC)(total
phenolic (TP) and total flavonoid (TF) contents and individual).

In Lactobacillus paracasei 0920 (FBJ) on carcinogen induction of aberrant


crypt foci (ACF), the abnormal tube-like glands in the lining of the colon and
rectum in rat colon by 2-Amino-1-methyl-6-phenylimidazo[4,5-b] pyridine
(PhIP) administrated intragastrically at a dose of 10 g/day, every day of the
experiment, rats fed with beetroot juice showed a significant improvement of
cytotoxic and genotoxic effects through increased the antioxidant status of
serum from 40% to 66% depending on the fraction.

In other words, oxidative stress induced production of toxins and toxic


chemical agents which may alternate DNA transcript were inhibited by
phytochemicals in beet juice.

2-Amino-1-methyl-6-phenylimidazo[4,5-b] pyridine (PhIP) is a toxic chemical


formed in condensation of creatinine found in muscle meats, with amino acids
in high temperature,

Interestingly, the formation of pro-oxidative stress found in blood of colorectal


carcinoma patients.was associated to decreased concentration of antioxidant
status together with lower amount of uric acid in expression of antioxidant
which was found to have a potential effect
in treatment of diseases associated with oxidative stress.
Furhtermore, levels of oxidative stress is also found in the measurement of
serum antioxidant status and the level of malondialdehyde, a marker of
oxidative stress in the rats kidneys and liver.

Additionally, in a male Wistar rat model of oxidative stress induced by N-


nitrosodiethylamine (NDEA) and carbon tetrachloride (CCl(4)), group fed with
beetroot juice per os, 8 mL/kg/day for 28 days, and a single i.p. dose of the
xenobiotics: 150 mg/kg NDEA or 2 mL/kg CCl(4) and xenobiotics only group,
treatment group showed a partial recovery in the activity of glutathione
peroxidase and glutathione reductase, by 35% and 66%, respectively.

Glutathione peroxidase (GPx) with peroxidase activity is an antioxidant with


function to protect the organism from oxidative damage.

The activity of glutathione reductase is a cellular antioxidant with function to


protect the organism against xenobiotics.

Particularly, the levels of Superoxide dismutase activity against oxidative stress


induced formation of inflammation also increased by 3-fold in compared to non
juice treatment group.

Importantly, treatment group also showed a significant inhibition of oxidative


stress in protected DNA damage caused by N-nitrosodiethylamine (NDEA) and
carbon tetrachloride (CCl(4)) by 20%.

These findings showed a remarkable efficacy of beet juice and products in


ameliorate free radicals and pro inflammatory expression through elevated
antioxidant status which warrant a human trial for validity.

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Biography
Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers
have been written and published on line, including world wide health, ezine
articles, article base, healthblogs, selfgrowth, best before it's news, the karate
GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ
by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington
Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as
international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Home-Processed Red Beetroot (Beta vulgaris L.) Products: Changes in
Antioxidant Properties and Bioaccessibility by Guldiken B1, Toydemir G2, Nur
Memis K3, Okur S4, Boyacioglu D5, Capanoglu E6.(PubMed)
(2) Protective effect of lactofermented red beetroot juice against aberrant crypt
foci formation, genotoxicity of fecal water and oxidative stress induced by 2-
amino-1-methyl-6-phenylimidazo[4,5-b] pyridine in rats modelm by Klewicka
E1, Nowak A, Zduczyk Z, Jukiewicz J, Cukrowska B.(PubMed)