IVF Clinic - Morpheus Meenakshi

International IVF Center

In Vitro Fertilization Program

Amid the in vitro treatment (IVF) process, eggs are expelled from the lady's body and joined
with sperm in the research facility to make incipient organisms, which a few days after the
fact are then moved into the lady's uterus. About 60% of IVF methodology in the United
States are performed on ladies 35 and more seasoned.

As told by ​Dr. Rajalakshmi. R​ of ​Morpheus Meenakshi International IVF Center​,

Before experiencing an IVF cycle in Connecticut, you will be endorsed a few meds to
empower the improvement of different ovarian follicles containing eggs to be treated. We
nearly screen this procedure utilizing blood tests and ultrasound. Once the eggs have
developed, they are recovered through a basic methodology under ultrasound direction. We
at that point uncover the recovered eggs to sperm and exchange it is possible that one yet
close to two of the subsequent incipient organisms again into your uterus.

In ​Morpheus Meenakshi International IVF Center IUI IVF Clinic​, ​The IVF Program
at Reproductive Medicine Associates of Connecticut (RMACT) has been extremely fruitful in
treating all reasons for sub-richness including:

❖ Endometriosis ​– pelvic irritation adversely influences the ordinary procedure of

origination
❖ PCOS (polycystic ovary disorder)​ – endocrine issue bringing about inability to
ovulate consistently
❖ Tubal Infertility​ – harmed or blocked fallopian tubes keep sperm and egg from
joining together
❖ Male Factor Infertility​ – low sperm tally, motility or irregular shape contrarily
influences a couple's possibility for origination
❖ Intermittent Pregnancy Loss​ – origination happens, yet the subsequent
pregnancies end rashly in premature delivery
❖ Auxiliary Infertility​ – couples who have just had at least one kids are experiencing
issues having more
❖ Unexplained Infertility​ – all fruitfulness testing is typical yet the couple is still not
imagining
❖ Intracytoplasmic Sperm Injection (ICSI)​ – ICSI has significantly enhanced the
treatment of serious male-factor barrenness because of low sperm tally. With ICSI, a
solitary sperm can be infused into the egg, bringing about an essentially higher
probability of preparation. This procedure is utilized as a part of conjunction with IVF.
❖ Helped Hatching​ – Assisted incubating includes control of the developing life to
expand the shot of a fruitful pregnancy in couples experiencing IVF. In this system, a
little entry point is made in the shell encompassing the developing life only before its
move into the uterus, improving the probability that implantation happens and that an
effective pregnancy comes about.
❖ Cryopreservation ​– Frequently, when a lady's ovaries are animated to expand the
quantity of eggs discharged, many eggs are acquired. At the point when these eggs
are treated, numerous developing lives might be made. After the suitable number of
 developing lives is exchanged to the uterus, patients have the choice of
cryopreservation (solidifying) to store the rest of the fetuses for later utilize.
❖ Preimplantation Genetic Diagnosis (PGD)​ – Preimplantation hereditary finding
enables us to recognize developing lives that convey the quality for certain hereditary
illnesses, for example, Tay-Sachs, sickle cell sickliness and cystic fibrosis. For
couples with a family history of acquired issue, PGD can essentially lessen the
hazard that the condition will be transmitted to their youngsters. PGD can likewise be
utilized for patients who experience the ill effects of unexplained repetitive pregnancy
misfortune.
❖ Elective Single Embryo Transfer (ESET)​ – Current rules from the American Society
for Reproductive Medicine suggest that conceptive endocrinologists exchange a
solitary developing life for ladies under 35 who have a decent shot of accomplishing
a pregnancy. Doing as such decreases the probability of a different pregnancy and
the dangers to both mother and youngster that are related with it. At RMACT, our
pregnancy achievement rates are so high (20% higher than the national normal) that
we never again exchange more than two incipient organisms in any patient. By and large,
just a single incipient organism is set into the uterus.

Explained by ​Dr. Rajalakshmi. R gynecologist​,

In Vitro Fertilization at RMA Connecticut Recognized for Scientific Excellence
The ripeness specialists at RMACT are all board guaranteed in Obstetrics and Gynecology
and Reproductive Endocrinology. They are individuals from the American Society for
Reproductive Medicine (ASRM), an intentional, non-benefit association gave to propelling
learning and mastery in regenerative medication and science. They are likewise individuals
from the Society for Assisted Reproductive Technology (SART), an association of helped
regenerative innovation suppliers subsidiary with ASRM that has gathered information and
distributed yearly reports of pregnancy achievement rates for fruitfulness centers in the U.S.
also, Canada since 1989.

Likewise, RMACT is completely licensed by both the Accreditation Association for

Ambulatory Health Care (AAAHC) and the American Institute of Ultrasound in Medicine
(AIUM).
Our Reproductive Endocrinology and Infertility Laboratory meets the most astounding
guidelines and is affirmed by the College of American Pathologists (CAP) and the Clinical
Laboratory Improvement Act (CLIA) for the State of Connecticut. Because of its aptitude and
experience, RMACT is one of only 11 driving In Vitro Fertilization (IVF) focuses across the
country picked by In Vitro Sciences to take an interest in its Centers of Excellence program.

PGS | Preimplantation Genetic

Screening Explained

The eventual fate of precise and tried and true hereditary developing life screening has
arrived: Preimplantation Genetic Screening (PGS) utilizing Next Generation Sequencing
(NGS).

Consistently a conceptive innovation tags along that upsets fruitlessness treatment.

Preimplantation Genetic Screening (PGS) by Next Generation Sequencing (NGS) is one
such innovation. PGS with NGS is a very predictable stage and is the eventual fate of
hereditary and developing life screening.

The reason for PGS is to break down, select and exchange just fetuses that have the fitting
number of chromosomes. Cutting edge Sequencing (NGS) takes into account high
determination screening which incorporates more inside and out investigation than just
tallying the chromosomes. Preimplantation Genetic Screening with NGS offers patients to a
great degree dependable outcomes with a straightforward expense structure.

Why Use Preimplantation Genetic Screening (PGS)?

Aneuploidy is the term used to portray any developing life with either excessively numerous
or excessively couple of chromosomes. The ordinary sum for people is 23 sets of
chromosomes, for a sum of 46. Twenty-two of these sets, called autosomes, appear to be
identical in the two guys and females. The 23rd sets, the sex chromosomes, chooses female
and male. The vast majority don't know that aneuploidy is the reason for more than 60% of
unsuccessful labors, and in addition the no doubt reason that patients don't get pregnant
from an in-vitro treatment (IVF) cycle with unscreened incipient organisms.
Screening developing lives ahead of time can help accomplish higher implantation rates and
less pregnancy misfortunes. The usage of PGS is especially essential for patients more than
35 as they are more inclined to chromosomal blunders in their eggs due to the "organic
clock", patients with numerous fizzled IVF cycles or implantation disappointment, and
patients with a past filled with numerous unnatural birth cycles or clinical Recurrent
Pregnancy Loss (RPL). This innovation likewise gives the capacity to prescreen to
aneuploidy conditions and chromosomal variations from the norm.

How PGS with NGS is Utilized

Utilizing PGS, we get 5-10 cells, from a few hundred cells, of a day 5 or 6 incipient organism
called a blastocyst. The capacity to decide this chromosomal data is critical in picking the
correct developing life for exchange. Numerous incipient organisms that are reviewed
construct exclusively in light of how they show up don't turn out to be chromosomally
ordinary. Then again, developing lives that don't show up as solid can be totally typical
chromosomally. Biopsying the developing life at a further developed cell arrange significantly
builds the precision of this testing and limits any potential harm that the biopsy can cause to
the fetus.

PGS with NGS and Elective Single Embryo Transfer (eSET)

Another preferred standpoint to using PGS with NGS is that this innovation can incredibly
diminish the chances of a patient having different pregnancies (twins or triplets) by having an
Elective Single Embryo Transfer or eSET. Doctors can recommend eSET, with the learning
that they are exchanging the most chromosomally fit incipient organism, along these lines
blocking the need to exchange various, unscreened developing lives with the expectation
that one will be sufficiently sound to make a continuous pregnancy and a solid infant.

Extra Facts about PGS with NGS

PGS isn't an immaculate science and has inalienable false positive and negative outcomes
because of the predetermined number of cells accessible for testing and incipient organism
mosaicism. In view of current information the mistake rate is under 1%. Likewise with any
innovation, we suggest that patients fail in favor of alert and when a pregnancy is set up,
conventional pre-birth determination like chorionic villus inspecting or amniocentesis ought to
be reliant of their obstetrician's proposal.

RMACT trusts Preimplantation Genetic Screening (PGS) with Next Generation Sequencing
(NGS) can be an advantage to any patient looking to build their odds of accomplishing a
solid pregnancy. For more data about PGS, or to talk with one of our board guaranteed
Reproductive Endocrinologists and barrenness experts, please get in touch with us. We're
here to help.

Time Test

Time Testing to Determine the Implantation Window

In vitro preparation (IVF) with developing life exchange, is the absolute best richness
treatment for fruitlessness over all age gatherings and determinations.

At the point when an IVF fetus exchange falls flat, it is exceptionally dispiriting and baffling to
patients and suppliers alike. In a scan for answers we think about the fetus itself, which is a
mix of sperm and egg, and we likewise consider the earth in which we are putting the
developing life.
The endometrial coating is exceptional tissue in the uterus where a developing life embeds
and is basic to a fruitful pregnancy. It customarily has been surveyed essentially by
ultrasound. Up to this point, there has been minimal solid testing accessible about the
endometrium itself to direct us concerning assessing endometrial receptivity to enhance the
implantation chances for any incipient organism.

What is the ERA Test?

The ERA (Endometrial Receptivity Analysis) is a hereditary test that assesses the statement
of qualities to assess whether the endometrial covering is appropriately created to
acknowledge a developing life. This innovation utilizes the most recent logical innovation
accessible to investigate the articulation levels of the 236 qualities to survey the ideal time to
put an incipient organism into the uterus to advance a fruitful implantation and pregnancy.
There is a little window of time that is ideal and in around 80% of ladies this window is in the
normal time.
Following quite a while of research and assessment of more than 12,000 examples the
examiners at Igenomix have discovered that around 20% (1 out of 5) of ladies have an
exceptional "window of implantation" that requires our standard developing life exchange
timing conventions to be adjusted. The expectation and aim of this test is to discover the
ladies who have a changed window of implantation and to alter the planning of prescriptions
to prompt a fruitful pregnancy.

The study of ERA includes tests for these 236 endometrial receptivity qualities which are
hybridized with RNA (ribonucleic corrosive). The tissue is gotten from an endometrial tissue
test gathered from the uterus through a methodology called an endometrial biopsy. After
hybridization, the flag powers are perused by an automated indicator and the example is
delegated "Responsive" or "Non-Receptive" as per its particular articulation profiles. Period
tests can uncover a requirement for an adjustment in the planning of incipient organism
exchange and allows customized developing life exchange (pET) timing in light of a person's
outcomes.

Why Choose the ERA Test?

The ERA test is prescribed for ladies with repetitive implantation disappointment,
characterized as ladies with at least two unsuccessful incipient organism exchanges. The
ERA test can expand the conceivable outcomes of an effective pregnancy in patients
seeking after solidified developing life exchange since we can time the incipient organism
exchange to be inside the window of time when implantation is well on the way to happen.
That is the way we can customize the season of the developing life exchange to every
patient. While ERA isn't important or fitting for each barrenness quiet, it has turned out to be
a key mediation for a few patients who were not discovering achievement generally.

For more data about the ERA test or to talk with one of our board-ensured Reproductive
Endocrinologists and fruitlessness masters, please reach us. We're here to help.

Elective Single Embryo Transfer

It has for quite some time been standard practice in the field of in vitro treatment (IVF) to
exchange numerous developing lives to enhance the odds that no less than one feasible
pregnancy will come about. Be that as it may, the procedure of numerous exchanges
presents expanded genuine dangers and entanglements to the two moms and newborn
children when twin, triplet and higher-arrange pregnancies happen. These confusions run
from preeclampsia and gestational diabetes to higher rates of C-segment and mental issues
for the mothers, and to rashness, birth complexities, long haul learning handicaps and
formative issues in their posterity. In one investigation led by the Centers for Disease Control
(CDC), half of the babies from numerous pregnancies had unfavorable results.

To address these worries, Reproductive Medicine Associates of Connecticut offers a choice

to its patients called Elective Single Embryo Transfer (ESET), or the exchange of only one
developing life at any given moment amid IVF. This approach is with regards to the rules of
the American Society for Reproductive Medicine (ASRM), which right now prescribes single
incipient organism exchange for ladies under 35 who have a decent possibility of
accomplishing a pregnancy.

Other than lessening the physical and mental dangers related with high-arrange
pregnancies, the danger of exorbitant confusions from a solitary developing life exchange is
considerably less than those related with different incipient organism exchanges. As
indicated by preparatory information from the CDC, single developing life exchange would
spare an aggregate of $1 billion in social insurance costs across the country.
In rundown, ESET is a practical choice for some ladies who pick IVF, particularly in the event
that they would prefer not to hazard a different pregnancy or on the off chance that they
have a prior medicinal condition that makes a numerous pregnancy hazardous. Patients are
encouraged to talk about the ESET CT alternative with their RMACT doctor to decide
whether it is the best decision for them.

For more data on ESET, reach us.

Contact Us
ELA
Ela Facebook
Ela Twitter
Ela Instagram
Ela You Tube
Ela Linkedin