Tumor bab 11

1. The RPE consists of a monolayer of hexagonal cells with apical microvilli and a
basement membrane at the base of the cells. This monolayer has the following
specialized functions:
a. vitamin A metabolism
b. maintenance of the outer blood-retina barrier
c. absorption of light
d. heat exchange
e. All of the above

Answer E ( AAO 2014-2015 Ophthalmic Pathology and Intraocular Tumors) pg 148

2. Albinism is a general term that refers to a congenital dilution of the pigment of the
skin, the eyes and the skin, or just the eyes. The condition results from genetic
mutations transmission is commonly
a. X-linked recessive
b. X-linked dominan recessive
c. Autosomal dominan
d. Autosomal dominan recessive
e. Y-linked recessive

Answer A ( AAO 2014-2015 Ophthalmic Pathology and Intraocular Tumors) pg 148

3. Generally, myelination of the nerve fibers in the optic pathways terminates at the
lamina cribrosa Myelinated nerve fibers have been associated with ?
a. Myopia
b. Amblyopia
c. Strabismus
d. Nystagmus
e. All of the above

Answer E ( AAO 2014-2015 Ophthalmic Pathology and Intraocular Tumors) pg 148

4. The Diagnosis of the figure above is?

a. Melanoma
b. Rubeosis iridis
c. Albinisme
d. Retionoblastoma
 e. Non all the above

Answer C ( AAO 2014-2015 Ophthalmic Pathology and Intraocular Tumors) pg 149

5. In Coats disease, exudative retinal detachment occurs as a result of leakage from

abnormalities in the peripheral retina, including?
a. telangiectatic vessels
b. macroaneurysms
c. saccular vasocontriction of retinal vessels
d. Fundus hypopigmentation
e. Iris transillumination

Answer A ( AAO 2014-2015 Ophthalmic Pathology and Intraocular Tumors) pg 149

6. Congenital hypertrophy of the RPE (CHRPE), a relatively common congenital lesion, is

characterized clinically by a flat, dark black lesion varying in size from a few to ?
a. 10 mm
b. 11 mm
c. 12 mm
d. 13 mm
e. 14 mm

Answer A ( AAO 2014-2015 Ophthalmic Pathology and Intraocular Tumors) pg 149

7. Acute retinal necrosis is a rapidly progressive, necrotizing retinitis caused by infection

with ?
a. HSV types 1 and 2
b. Rubella
c. Measles
d. human immunodeficiency virus (HIV)
e. all of the above

Answer A ( AAO 2014-2015 Ophthalmic Pathology and Intraocular Tumors) pg 151

8. to analysis of aqueous or vitreous biopsy specimens can be used to rapidly

demonstrate the viral cause of ARN is?
a. Polymerase chain reaction (PCR)
b. Electron microscopy
c. Hystologi
d. Frozen section
e. Kultur

Answer A ( AAO 2014-2015 Ophthalmic Pathology and Intraocular Tumors) pg 151

 9. CMV retinitis is an opportunistic infection that may occur in immunosuppressed
patients, especially AIDS patients. Acute lesions show large neurons ?
a. (10- 20 m)
b. (20- 30 m)
c. (30- 40 m)
d. (40- 50 m)
e. (50- 60 m)

Answer B ( AAO 2014-2015 Ophthalmic Pathology and Intraocular Tumors) pg 151

10. Typical peripheral cystoid degeneration (TPCD) is a universal finding in the eyes of
persons older than ?
a. 20 years
b. 30 years
c. 40 years
d. 50 years
e. 60 years

Answer A ( AAO 2014-2015 Ophthalmic Pathology and Intraocular Tumors) pg 154

11. The most important histopathologic features oflattice degeneration include ?

a. discontinuity of the ILM of the retina
b. an overlying pocket of liquefied vitreous
c. sclerosis of the retinal vessels, which remain physiologically patent
d. condensation and adherence of vitreous at the margins of the lesion
e. All of the above

Answer E ( AAO 2014-2015 Ophthalmic Pathology and Intraocular Tumors) pg 155

12. In contrast to retinal vascular occlusion, which leads to inner retinal ischemia,
occlusion of the choriocapillaris can lead to loss of the outer retinal layers and RPE.
This type of atrophy called ?
a. Mutton fat
b. paving-stone degeneration
c. Papil atrophy
d. CSME
e. Not all of the above

Answer B ( AAO 2014-2015 Ophthalmic Pathology and Intraocular Tumors) pg 156

13. There are many causes of retinal ischemia, including ?

a. radiation retinopathy
b. retinopathy of prematurity
c. sickle cell retinopathy
 d. carotid occlusive disease
e. all of the above

Answer E ( AAO 2014-2015 Ophthalmic Pathology and Intraocular Tumors) pg 156