LESSON PLAN ON CELL TRANSPORT MECHANISMS

I. OBJECTIVES

At the end of the discussion, the students should be able to:

1. describe the structural components of the cell membrane

(STEM_BIO11/12–Ig-h-11)
2. relate the structure and composition of the cell membrane to its function
(STEM_BIO11/12-Ig-h-12)
3. explain transport mechanisms in cells (diffusion, osmosis, facilitated
transport, active transport) (STEM_BIO11/12–Ig-h-13)
4. differentiate exocytosis and endocytosis (STEM_BIO11/12-Ig-h-14)
5. perform a simulation laboratory work (Membrane Diffusion Lab) using
PhET simulation software.

II. SUBJECT MATTER

A. Topic: Cell Transport Mechanism

B. References:
1. Campbell, N. J. (2010). Biology 9th edition Pearson International
Edition. Benjamin Cummings Publishing.
2. PhET website:
https://phet.colorado.edu/en/simulation/legacy/membrane- channels
3. Plasma Membrane:
https://www.wiley.com/college/boyer/0470003790/animations/membrane_t
ransport/membrane_transport.htm
4. General Biology 1 Teaching Guide, pages 50-56

C. Materials: PowerPoint Presentation, laptop or tablet (with PhET simulation

software), activity sheets (Cell Membrane Transport)

III. PROCEDURE

A. Routinary Activities

1. Greetings

2. Classroom Management

3. Prayer

4. Checking of Attendance

5. Review/Game:

Scrambled Letters
The students will arrange the scrambled letters flashed on the screen and the
students should guess what term is it. Answers shall be flashed on the screen
afterwards.

The teacher will then say:

The cell is the basic unit of life. Our body is made up of billions of them. A cell
is like a tiny system. Inside the cell are organelles with different functions.
Among these organelles are: nucleus, mitochondria, Golgi bodies, cell
membrane and cell wall.

B. Motivation

4 PICS 1 WORD
 The students will arrange the scrambled letters flashed on the screen and the
students should guess what the word is using the picture clues. Answers shall
be flashed on the screen afterwards. Answers: CELL, ACTIVE, PASSIVE,
TRANSPORT.

C. Lesson Proper

Teacher Discussion using PowerPoint Presentation about Transport Mechanisms

1. Present an illustration of the plasma

membrane to the class. Explain how
plasma membranes are arranged in the
presence of water.

Say, “ This is the plasma membrane of

the cell.”

2. Describe the plasma membrane and

discuss its importance and how
indispensable it is to the life of the cell.
The teacher presents it through the
webpage,

https://www.wiley.com/college/boyer/047
0003790/animations/membrane_transpor
t/membrane_transport.htm.

3. Let students enumerate structures

found in a plasma membrane. Make
students understand the structure of a
phospholipid bilayer. The parts can be
seen in the image flashed in the
website.

Say, “What are the structures do you

see in the plasma membrane? What is
the importance of the phospholipid
bilayer? ”

The students can enumerate integral proteins, peripheral proteins, cholesterol,

phospholipid heads and fatty acid tails.

4. Enumerate the different transport

mechanisms. Say, “There are two types
of transport mechanisms: the passive
and the active transport. Passive
transport does not require cellular
energy and it goes with the
concentration gradient. Examples are
diffusion, facilitated diffusion and
osmosis. Active transport requires
cellular energy to occur and it goes
against the concentration gradient.
Examples are endocytosis and
exocytosis.”

The teacher will also emphasize the

concept of concentration gradient. Say,
“The concentration gradient is the
distribution of particles across space
from high to low concentration.”
5. Explain deeper the passive transport
and differentiate between diffusion,
facilitated diffusion and osmosis. Say,
“Energy for passive transport comes
from the molecules themselves. In
passive transport, molecules move with
the concentration gradient, that is, from
high concentration to low
concentration.”

“Diffusion is the primary means of cell

transport where molecules move from
high to low concentration. The movement continues with the gradient until the
molecules are evenly distributed, thus, equilibrium is achieved.”

The teacher will show the concept of diffusion using the PhET simulation
(Membrane Channels).

“Facilitated diffusion is when particles move with the concentration gradient

across a transport protein in the membrane. Ions, sugar and amino acids all
move into and out of cells by facilitated diffusion. Osmosis is the diffusion of
water through a membrane. If the concentration of water is higher outside a cell
than inside, water moves into the cell. If the concentration of water is higher
inside of a cell than outside, the water moves out of the cell.

The teacher will show the concept of osmosis using the PhET simulation
(Membrane Channels).

6. Differentiate hypertonic, hypotonic

and isotonic solutions. Say, “Hypertonic
solution is a solution with a higher
concentration of solute. Hypotonic
solution is a solution with a lower
concentration of solutes. Isotonic
solution is a solution of equal solution
concentration.”

The teacher will show the concept of

hypertonic, hypotonic and isotonic
solutions using the PhET simulation (Membrane Channels).

7. Discuss about active transport and differentiate endocytosis, phagocytosis,

pinocytosis, receptor-mediated endocytosis, and exocytosis.

Say ”Active transport uses cellular

energy/ATP and it goes against the
concentration gradient, that is, from low
concentration to high concentration.
There are two types: endocytosis and
exocytosis. Endocytosis takes things into
cells. Examples are: phagocytosis, which
is cell eating or taking in of food;
pinocytosis, which is cell drinking or
taking in of liquid and receptor-mediated
endocytosis. is a complicated mechanism
involving the transport of materials
through coated vesicles. Cells take up
molecules more efficiently in this process
due to the receptor proteins on their
surfaces. Each receptor protein bears a
binding site for a particular molecule. If
the right molecule contacts a receptor
protein, it attaches to the binding site,
forming a pocket and eventually pinching
off into the cytoplasm.”

Activity: PhET Sims Activity on Cell Membrane Transport

The teacher will distribute the activity sheet entitled “Cell Membrane Transport” to
the students. Instructions about the activity will proceed as indicated in the
activity sheets. The students will be grouped. Each group will answer the activity
using the PhET simulation software downloaded in the laptop or tablet (one for
each group). Checking and discussion about the activity follows.

D. Generalization

Concept Mapping

The teacher will summarize the lesson using the concept map shown
below:

E. Application

The students will download the Membrane Diffusion Lab worksheet from
the website: http://phet.colorado.edu/en/simulation/membrane-channels.

In this investigation, the students will explore the process of diffusion

across a semi-permeable cell membrane using the PhET simulation
software.

IV. EVALUATION

The teacher will flash the following questions in the screen.

Direction: Provide the information being asked. Write your answers on a

1⁄4 sheet of yellow paper.

1. The cell membrane is made up of _______ bilayer.

2. ___________ is a cell transport that goes with the concentration
gradient.
 3. Active transport requires ________________ for it to occur.
4. The concentration gradient is the distribution of particles across space
from __________ to __________ concentration
5. Particles move with the concentration gradient across a transport
protein in the membrane in a ______________.

V. ASSIGNMENT

Research

The students will do a research work about the cell transport mechanism
of a neuron especially in nerve impulse transmission.

Prepared by:

Michael Jay O. Mesa

SST-II