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REFERAT

Pendekatan Diagnosis dan Tatalaksana Hepatitis Akut dan Kronis


Kepaniteraan Klinik Bagian Ilmu Penyakit Dalam
RS Kepresidenan RSPAD Gatot Soebroto

Disusun oleh
GHINA ATHIRAH
1710221034

Pembimbing:
Letkol Ckm (K) dr. Diany Nuriana Tahar, Sp. PD

FAKULTAS KEDOKTERAN
UNIVERSITAS PEMBANGUNAN NASIONAL “VETERAN” JAKARTA
2017
DAFTAR ISI

PENGESAHAN ....................................................................................................... i
KATA PENGANTAR ............................................................................................ ii
DAFTAR ISI .......................................................................................................... iii
DAFTAR GAMBAR ............................................................................................. iv

BAB I PENDAHULUAN ....................................................................................... 1


I.1 Latar Belakang ............................................................................................ 1
I.2 Tujuan ....................................................................................................... 3

BAB II TINJAUAN PUSTAKA ............................................................................ 4


II.1 Anatomi dan fisiologi hati........................................................................... 4
II.2 Definisi hepatitis ......................................................................................... 5
II.3 Prevalensi hepatitis...................................................................................... 5
II.4 Klasifikasi .................................................................................................. 6
II.5 Manifestasi klinis .................................................................................... 10
II.6 Pemeriksaan penunjang............................................................................. 11
II.7 Diagnosis .................................................................................................. 14
II.8 Tatalaksana .............................................................................................. 16

BAB III KESIMPULAN .................................................................................... 24

DAFTAR PUSTAKA ........................................................................................... 25


DAFTAR GAMBAR

Gambar 1 Angka kematian akibat komplikasi hepatitis di wilayah Asia


Tenggara tahun 2015..................................................................................... 2
Gambar 2 Anatomi hati .............................................................................................. 4
Gambar 3 Prevalensi kejadian hepatitis Indonesia tahun 2007 & 2013..................... 5
Gambar 4 Skema gambaran khas dan laboratorium hepatitis A akut................................. 7
Gambar 5 Bagian partikel virus hepatitis B ..................................................................... 8
Gambar 6 Gambaran serologis pada infeksi virus hepatitis B kronik ................................. 9
Gambar 7 Gambaran serologis pada infeksi virus hepatitis B akut .................................. 13
Gambar 8 Kriteria diagnosis hepatitis B menurut PPHI 2012.......................................... 15
Gambar 9 Interpretasi pemeriksaan serologis infeksi virus hepatitis C ............................. 15
Gambar 10 Algoritma terapi hepatitis B kronik pada kadar HBeAg positif ....................... 17
Gambar 11 Algoritma terapi hepatitis B kronik pada kadar HBeAg negatif ...................... 18