Though currently divorced, he has been married three times with his

third wife from Spain. He has two daughters, the eldest, Robin; who is an
epidemiologist at Chicago Med, and the much younger Anna. He
struggles with depression.

Season 1

Derailed

He has a great attachment to a patient named Jimmy, a boy who has

been in and out of the hospital since he was 8 years old. Dr. Charles met
him when he was first brought in to help Jimmy cope with his condition.
However, Jimmy helped him too. He made sure to be present when he
woke up from his lung transplantation surgery.

At the end of episode 1x12, it's revealed Dr. Charles suffers from
depression. His doctor is walking with him through a bridge. He tells her
he has been off the medication since he was feeling fuzzy and needed
full focus to treat patients at the Hospital. He was afraid of making some
misdiagnosis. She tells him he can't treat patients if he himself is
depressed so she wants to re-adjust his doses.

Season 2

Dr. Charles recruits Sarah Reese as a trainee psychiatrist after she quits
Pathology in season 1 finale.

In 2x09, Dr. Charles reveals that he had a brother who overdosed. This is
after he, Reese and Rhodes are in a disagreement over whether a patient
is eligible for a heart transplant or not since she was addicted before. Dr
Charles is reluctant to give her a yes as he feels she will relapse like his
brother did.

Later on, Reese has a breakdown after a difficult case and says she isn't
cut out to be like him. He persuades her.
In 2x23 Love Hurts, As Dr. Charles is leaving the hospital after a long
day, he is approached by an upset Jack Kellog who tells him that he has
been waiting for him all day and that he hasn't answered any of his
messages. Dr. Charles tells him that he had an unusual day(his daughter
Robyn was in the hospital and they found out the cause of her
psychiatric symptoms). Before he can finish Jack Kellog yells,"LIAR",
pulls out a small revolver and shoots Dr. Charles in the Left Abdominal
Area of his body at close range. After realizing what he has done, he
shoots himself in the head. Staff and security personnel star running
towards the scene. His condition is unknown.

Memorable Quotes

(To Connor): Is that your dad? (-Yep.) Fathers like that keep me in
business baby! (laughs)

(To Sharon):

-Sharon: "Look at this ED Daniel, we don't get this without that. Downey
helps make Chicago Med a destination Hospital"

-Charles "Yeah, Like Disneyland!"

(to...): "Sometimes, when somebody that we love gets sick, very easy to
lose sight of the person and see only the disease. Remembering that our
loved one is still there? Not always easy."

Trivia

He touches his chin when bluffing.