C1
C2
Cervical spinal C3
nerves C4
C5
C6
Cervical
C7
enlargement
C8
T1
T2
T3
T4
T5
T6
T7
Thoracic T8
spinal Posterior
nerves T9 median sulcus
T10
T11 Lumbosacral
enlargement
T12
L1 Conus
medullaris
L2
Lumbar L3 Inferior
spinal tip of
nerves spinal cord
L4
Cauda equina
L5
S1
Sacral spinal
S2
nerves
S3
S4
S5
Dorsal root
Central Gray
canal matter
Spinal Ventral
nerve root Anterior median fissure
C3
T3
L1
S2
Dorsal root
Central Gray
canal matter
Spinal Ventral
nerve root Anterior median fissure
C3
T3
L1
S2
Ventral root
Spinal nerve
Arachnoid mater
Dura mater
Anterior median
fissure
Pia mater
Denticulate
ligaments
Arachnoid mater
(reflected)
Dura mater
(reflected)
Spinal blood
vessel
Dorsal root of
sixth cervical
nerve
Ventral root of
sixth cervical
nerve
Anterior view of spinal cord showing meninges and spinal nerves. For this
view, the dura and arachnoid membranes have been cut longitudinally and
retracted (pulled aside); notice the blood vessels that run in the
subarachnoid space, bound to the outer surface of the delicate pia mater.
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Sectional Anatomy of the Spinal Cord
• Gray matter
• Central canal
• Consists of somas (cell bodies) surrounding
the central canal
• White matter
• Consists of axons
• Nerves are organized into tracts or columns
• Located outside the gray matter area
Lateral Visceral
gray horn Motor
nuclei
Anterior Somatic
gray horn
To ventral
Anterior gray root
commissure
Anterior median
fissure
The left half of this sectional view shows important anatomical landmarks; the right half indicates
the functional organization of the gray matter in the anterior, lateral, and posterior gray horns.
Lateral
white
column
(funiculus) Flexors
Extensors Hand
Forearm
Arm
Shoulder
Trunk
The left half of this sectional view shows the major columns of white matter. The right half
indicates the anatomical organization of sensory tracts in the posterior white column for
comparison with the organization of motor nuclei in the anterior gray horn. Note that both
sensory and motor components of the spinal cord have a definite regional organization.
C1
C2
Cervical spinal C3
nerves C4
C5
C6
Cervical
C7
enlargement
C8
T1
T2
T3
T4
T5
T6
T7
Thoracic T8
spinal Posterior
nerves T9 median sulcus
T10
T11 Lumbosacral
enlargement
T12
L1 Conus
medullaris
L2
Lumbar L3 Inferior
spinal tip of
nerves spinal cord
L4
Cauda equina
L5
S1
Sacral spinal
S2
nerves
S3
S4
S5
• Spinal nerves
• Each peripheral nerve consists of:
• Epineurium: outer layer – becomes continuous
with the dura mater
• Perineurium: layer surrounding a fascicle – a
fascicle is a bundle of axons
• Endoneurium: layer surrounding a single axon
Blood vessels
Connective Tissue
Layers
Epineurium covering
peripheral nerve
Perineurium (around
one fascicle)
Endoneurium
Schwann cell
Myelinated
axon
A typical peripheral Fascicle
nerve and its connective
tissue wrappings
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Spinal Nerves
Dorsal ramus
Ventral ramus
To skeletal
muscles of body
wall, limbs Ventral
root
Postganglionic fibers to
smooth muscles, glands,
etc., of body wall, limbs
Spinal nerve
KEY
Somatic motor Preganglionic fibers to
commands sympathetic ganglia
innervating abdomino-
Visceral motor
commands pelvic viscera
The distribution of motor neurons in the spinal cord and motor fibers within the spinal
nerve and its branches. Although the gray ramus is typically proximal to the white ramus,
this simplified diagrammatic view makes it easier to follow the relationships between
preganglionic and postganglionic fibers.
© 2012 Pearson Education, Inc.
Spinal Nerves
Dorsal ramus
Ventral ramus
From exteroceptors,
proprioceptors of
body wall, limbs Dorsal
root
ganglion
From interoceptors
of body wall, limbs
Rami
communicantes
Ventral
KEY root
Somatic
sensations
Visceral
From interoceptors
sensations of visceral organs
A comparable view detailing the distribution of sensory neurons and sensory fibers
© 2012 Pearson Education, Inc.
Spinal Nerves
• Dermatomes
• Each pair of spinal nerves monitors specific
surface areas
• These are clinically important areas regarding
surgery
NV
C2–C3
C2
C3 C3
C4
T2 C4
C5
T3
T1
T2 T4
T5 C5
T3 T6
T4 T7
T5 T8
T6 T9 T2
T2 T7 T 10
T 11
T8
T 12
T9 L1 C6
T 10 L2
T 11 L4 L3 T1
C6 C7
T 12 L5
L1
SS
L2 S2 4 3
C8
C8
T1 L3 L1
C7 S5
S1 L5
L4
L2 S2
L5 L3
S1
L4
ANTERIOR POSTERIOR
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Nerve Plexuses
Superior
Gluteal
Inferior nerves
Pudendal nerve
Sciatic nerve
Saphenous nerve
Tibial nerve
Accessory
nerve (N XI)
Cranial
Hypoglossal
nerves
nerve (N XII)
Great auricular nerve
Lesser occipital
nerve
C1
C2
Omohyoid muscle
Supraclavicular Phrenic nerve
nerves
Clavicle Sternohyoid muscle
Sternothyroid muscle
Musculocutaneous
nerve
Median nerve
Ulnar nerve
Radial
nerve
Lateral antebrachial
cutaneous nerve
Anterior
Anterior view of the brachial plexus and upper limb Distribution of
showing the peripheral distribution of major nerves cutaneous nerves
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Nerve Plexus
MIDDLE
Lateral cord TRUNK C7 BRACHIAL
PLEXUS
Posterior cord
Lateral pectoral nerve C8
MIDDLE
Lateral cord TRUNK C7 BRACHIAL
PLEXUS
Posterior cord
Lateral pectoral nerve C8
Musculocutaneous
nerve
Median nerve
Ulnar nerve
Radial
nerve
Lateral antebrachial
cutaneous nerve
Anterior
Anterior view of the brachial plexus and upper limb Distribution of
showing the peripheral distribution of major nerves cutaneous nerves
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Figure 14.10c The Brachial Plexus
Musculocutaneous
nerve
Axillary nerve
Branches of
axillary nerve
Radial nerve
Ulnar nerve
Median nerve
Posterior antebrachial
cutaneous nerve
Deep branch of
radial nerve
Superficial branch
Radial
of radial nerve
nerve
Median
nerve
Posterior
Distribution of
cutaneous nerves
Right common
Cervical carotid artery
Clavicle, cut plexus
and removed
Brachial plexus
Deltoid muscle (C5–T1)
Musculocutaneous Sternocleido-
nerve mastoid muscle,
sternal head
Right axillary artery
over axillary nerve
Sternocleido-
Median nerve
mastoid muscle,
Radial nerve clavicular head
Biceps brachii,
long and short heads Right subclavian
artery
Ulnar nerve
Median
nerve
© 2012 Pearson Education, Inc.
Table 14.2 The Brachial Plexus
T12
L1
L5
Lumbosacral trunk
S1
SACRAL
Superior gluteal nerve PLEXUS
S2
Inferior gluteal nerve
S3
S4
Sciatic nerve S5
Iliohypogastric nerve
Ilioinguinal nerve
Genitofemoral nerve
Lateral femoral
cutaneous nerve
Femoral nerve
Pudendal nerve
Posterior femoral
cutaneous nerve (cut) Obturator nerve
Sciatic nerve
Saphenous
nerve
Sural
Saphenous nerve nerve
Fibular
nerve
Common fibular
nerve
Saphenous Sural
nerve nerve
Posterior femoral
Pudendal
cutaneous nerve
nerve
Sciatic nerve
Saphenous
nerve
Sural
nerve
Fibular
Tibial nerve
nerve Common fibular
nerve
Medial sural
cutaneous nerve
Lateral sural
Tibial cutaneous nerve
nerve
Saphenous
Sural nerve
nerve
Sural nerve
Saphenous Sural
nerve nerve Medial plantar
nerve
Lateral plantar
Tibial Fibular The sacral plexus,
nerve
nerve nerve
posterior view
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Figure 14.13c The Lumbar and Sacral Plexuses, Part II (Part 1 of 2)
Gluteus maximus
(cut) Gluteus medius
(cut)
Inferior gluteal Gluteus minimus
nerve
Pudendal nerve Superior gluteal
nerve
Perineal branch
Hemorrhoidal Piriformis
branch
Posterior femoral
cutaneous nerve
Perineal branches
Sciatic
nerve
Descending
cutaneous
branch
Medial sural
cutaneous Lateral sural
nerve cutaneous
nerve
Gastrocnemius
Small saphenous
vein
Sural nerve
Calcaneal tendon
Tibial nerve
(medial calcaneal
branch)
Gluteus maximus
Gluteus medius
Gluteus minimus
Tibial branch
Internal
pudendal Common fibular Components of
artery branch sciatic nerve
Greater trochanter of femur
Pudendal
nerve Posterior femoral
cutaneous nerve
Nerve to
gemellus
and
obturator
internus Gluteus
maximus
Biceps femoris
Tibial nerve
Sartorius
Gracilis Lateral sural
cutaneous nerve
Semimembranosus
Common fibular
Popliteal artery nerve
Semitendinosus Plantaris
Medial sural
cutaneous nerve
Spinal cord
emerging from
foramen magnum
Cervical
plexus
(C1–C5) Cervical
spinal
nerves
(C1–C8 )
Brachial
plexus
(C5–T1)
Thoracic
spinal
nerves
(T1–T12)
Lumbar
plexus
Lumbar
(T12–L4)
spinal
nerves
(L1–L5)
Sciatic
Sacral nerve
plexus
(L4–S4)
Sacral spinal
Coccygeal nerves (Co1) nerves (S1–S5)
emerging from
sacral foramina
• Reflex
• An immediate involuntary response
• Reflex arc
• The neural “wiring” of a single reflex
• Begins at a sensory receptor and ends at a
peripheral receptor
REFLEX
ARC
Receptor
Stimulus
Reflexes
can be classified by
Sensory
CENTRAL
receptor NERVOUS
Ganglion
SYSTEM
Sensory
neuron
CENTRAL
Ganglion NERVOUS Interneurons
Sensory SYSTEM
neuron
Motor Circuit 2
neuron
Circuit 1 Motor
neurons
Sensory
receptor
(muscle
spindle) Skeletal muscle 1
Skeletal muscle
Skeletal muscle 2
A monosynaptic reflex circuit involves a peripheral A polysynaptic reflex circuit involves a sensory neuron,
sensory neuron and a central motor neuron. In this interneurons, and motor neurons. In this example, the
example, stimulation of the receptor will lead to a stimulation of the receptor leads to the coordinated
reflexive contraction in a skeletal muscle. contractions of two different skeletal muscles.
• Stretch reflex
• 1. Stimulus stretches a muscle
• 2. Activates a sensory neuron
• 3. Information is processed in the spinal cord
• 4. Motor neurons are activated
• 5. Muscle (effector) contracts
Information processing
at motor neuron
Receptor
(muscle
spindle)
Spinal cord
Stretch
REFLEX
ARC
Stimulus
Effector
KEY
Sensory neuron
(stimulated)
Contraction
Motor neuron
(stimulated)
The patellar reflex is controlled by muscle spindles in the quadriceps group. The
Response stimulus is a reflex hammer striking the muscle tendon, stretching the spindle
fibers. This results in a sudden increase in the activity of the sensory neurons,
which synapse on spinal motor neurons. The response occurs upon the activation
of motor units in the quadriceps group, which produces an immediate increase in
muscle tone and a reflexive kick.