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DAFTAR ISI

Halaman

HALAMAN JUDUL ........................................................................................... i


DAFTAR ISI ........................................................................................................ iii
DAFTAR GAMBAR ........................................................................................... v

BAB I Pendahuluan ............................................................................................ 1


1.1 Latar Belakang ......................................................................................... 1
1.2 Rumusan Masalah.................................................................................... 3
1.3 Tujuan Penelitian ..................................................................................... 3
1.4 Kegunaan Penelitian ................................................................................ 4
1.4.1 Kegunaan Teoritis........................................................................... 4
1.4.2 Kegunaan Praktis ............................................................................ 4

BAB II. Kajian pustaka, Kerangka Pemikiran,dan Hipotesis ........................ 5


2.1. Kajian pustaka ........................................................................................ 5
2.1.1 Farmakokinetik ............................................................................... 5
2.1.2 Jahe Merah (Zingiber officinale var. Rubrum) .............................. 7
2.1.2.1 Klasifikasi dan Deskripsi Tanaman ......................................... 7
2.1.2.2 Kandungan Kimia, Aktivitas Farmakologi, dan Toksisitas ..... 9
2.1.3 Obat Herbal Jahe Merah (Zingiber officinale var. Rubrum) ......... 11
2.1.4 Pengujian Klinik ............................................................................. 12
2.2 Kerangka Pemikiran ............................................................................... 15
2.3 Premis ..................................................................................................... 16
2.4 Hipotesis ................................................................................................. 17

BAB III. Metode Penelitian ................................................................................ 18


3.1 Alat ......................................................................................................... 18
3.2 Bahan ...................................................................................................... 18
3.3 Metode .................................................................................................... 19
3.3.1 Tahap Persiapan ............................................................................ 19
3.3.1.1 Pengajuan Kode Etik......................................................... 19

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3.3.1.2 Determinasi Tanaman ....................................................... 19
3.3.1.3 Penyiapan Obat Herbal Z. officinale var. Rubrum ............ 19
3.3.1.4 Penyiapan Larutan Standar ............................................... 19
3.3.2 Validasi Metode ............................................................................ 21
3.3.3 Analisis Kualitatif 6-Shogaol Dalam Obat Herbal Z. officinale var.
Rubrum .......................................................................................... 24
3.3.4 Penetapan Profil Farmakokinetik dari Obat Herbal Jahe Merah (Z.
officinale var. Rubrum) dihitung Sebagai 6-Shogaol ................... 24
DAFTAR PUSTAKA .......................................................................................... 27

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DAFTAR GAMBAR

Gambar 2.1.2.1 Tanaman dan rimpang jahe merah (Zingiber. officinale var.
Rubrum) .................................................................................... 23
Gambar 2.1.2.2 Struktur kimia 6-shogaol .......................................................... 10
Gambar 2.2 Diagram Kerangka Pemikiran .................................................... 15

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