Item (Months) Date Notes Months 1-7: Preliminary Research and Materials Acquisition 1- Nov- Literature review 2 18 Potentially ongoing 1- Nov- Review and revise task list 1 18 1- Nov- Revise timetable and budget 1 18 1- Aug- Only for preliminary studies, dependent Obtain supplies 1 18 on Literature Review 1-Sep- Obtain license from Dr. Leiber 2 18 Months 8-19: Mice Studies 1- Dec- Obtain mice 1 18 Must be genetically identical 1-Jan- Prove tremors exists in mice 1 19 1-Apr- Variable timetable, due to unknown Implant neural net 4 19 ability for implantation 1- Use TMS to stimulate function of May- neurons 1 19 1- May- Use midazolam to inhibit neurons 1 19 Might use a different inhibitor Study without neural function 1-Jun- manipulation 1 19 1-Sep- Compare with literature review 3 19 Month 20: Reserve Months 21-32: Pig Studies 1- Nov- Obtain pigs 1 19 Must be genetically identical 1- Dec- Prove tremors exist in pigs 1 19 1-Apr- Variable timetable, due to unknown Implant neural net 4 20 ability for implantation 1- Use TMS to stimulate function of May- neurons 1 20 1- May- Use midazolam to inhibit neurons 1 20 Might use a different inhibitor study without neural function 1-Jun- manipulation 1 20 Compare with literature review and 1-Sep- mice study 3 20 Month 33: Reserve Months 34-46: Human Studies 1- Dec- Gather Parkinson's disease sufferers 2 20 Smaller sample size 1-Jan- Prove tremors exist in humans 1 21 1- May- Variable timetable, due to unknown Implant neural net 4 21 ability for implantation Use TMS to stimulate function of 1-Jun- neurons 1 21 1-Jun- Use midazolam to inhibit neurons 1 21 Might use a different inhibitor Study without neural function 1-Jul- manipulation 1 21 Compare with literature review, 1-Oct- mice, and pigs studies 3 21 Month 47: Reserve Months 48-52: Analysis and Publishing 1- Dec- Create a plausible method of action 1 21 1- Mar- Write a paper 3 21 1-Apr- Submit the paper for publication 1 21