Palmar erythema Excess oestrogen associated with reduced hepatic breakdown of sex streoids
Spider naevi Excess oestrogen associated with reduced hepatic breakdown of sex streoids
Hepatomegaly 1. Chronic parenchymal liver disease- alcoholic liver disease, hepatic stenosis, viral
hepatitis
2. Malignancy – primary hepatocellularcancer, secondary metastatic cancer
3. Right heart failure
4. Haematological disorders- lymphoma, leukemia, polycythemia, myelofibrosis
5. Rarities – amyloidosis, sarcoidosis
Splenomegaly 1. Haematological disorders – lymphoma, haemolytic anaemia, polycythemia rubra
vera
2. Portal hypertension –
3. Infection – malaria, tuberculosis, salmonellosis, bacterial endocarditis
4. Rheumatological condtions – SLE
Hepatosplenomegaly Lymphoma, myeloproliferative didease, cirrhosis with portal hypertension, amyloidosis,
sarcoidosis