Name of Indication Mechanism Of Contraindicati Side effect / adverse effect Nursing

Drug Action on Consideration

Mannitol Acute oliguric Increases osmotic Susceptibility Dehydration Vital signs
renal failure. pressure of
Brand plasma in Dehydration Anuria Intake and output
Name: Toxic overdose glomerular
Lasix filtrate, inhibiting Intracranial bleeding Signs and
Edema tubular symptoms of
Classificatio reabsorption of Headache dehydration (e.g.
n: Increased water poor skin turgor,
Diuretics intracranial andelectrolytes Blurred vision dry skin, fever,
pressue (ICP) (including sodium thirst)
and potassium). Nausea and vomiting
Intraocular These actions Signs of electrolyte
pressure (IOP) enhance water Volume expansion imbalance/deficit
flow from various (e.g. muscular
tissuesand Chest Pain weakness,
ultimately paresthesia,
decrease numbness,
intracranial and confusion, tingling
intraocular sensation of
pressures extremity and
excessive thirst)
Name of Indication Mechanism Of Contraindicati Side effect / adverse effect Nursing
Drug Action on Consideration
Hemostan Treatment and Tranexamid acid Allergic Gastrointestinaldisturbances. Assess patient’s
prophylaxis of competitively reaction to history, if with
Drug hemorrhage inhibits activation the drug or Hypotension,particularly after rapid IV active intravascular
classes: associated with of plasminogen hypersensitivi administration. clotting,predispose
antifibrinol excessive (via bonding to ty d to
ytics. fibrinolysis the kringle Thromboticcomplications have been thrombosis;hemorr
domain), thereby Presence of reported. hage due to
reducing bloodclots disseminated
conversion of (eg, in theleg, Instances of transientdisturbance of intravascular
plasminogen to lung, colourvision associated withits use coagulation
pasmin an enzyme eye,brain),
that degrades have a history Monitoranticoagula
fibrin clots, of bloodclots, nt cove
fibrinogen and or are at risk
other plasma for blood clot
proteins including
the procoagulant
factors V and VIII
Name of Drug Indication Mechanism Of Action Contraindication Side effect / Nursing Consideration
adverse effect
amlodipine Chest pain These medications Hypersensitivity. Side effects of Monitor BP for
(angina) occurs block the transport of amlodipine are therapeuticeffectiveness.
Classification: because of calcium into the generally mild and BP reduction is greatest
antihypertensive insufficient oxygen smooth muscle cells reversible. The after peak levels of
agent delivered to the lining the coronary two most amlodipine are achieved
heart muscles. arteries and other common side Oral doses.
Insufficient arteries of the body. effects are
oxygen may be a Since calcium is headache and Monitor for S&S of dose-
result of coronary important in muscle edema (swelling) related peripheral orfacial
artery blockage or contraction, blocking of the lower edema that may not be
spasm, or because calcium transport extremities. Less accompanied by weight
of physical relaxes artery common side gain; rarely, severe edema
exertion which muscles and dilates effects include may cause discontinuation
increases heart coronary arteries and dizziness, flushing, of drug.
oxygen demand in other arteries of the fatigue, nausea,
a patient with body. By relaxing and palpitations
coronary artery coronary arteries, Monitor BP with postural
narrowing. amlodipine is useful changes. Report postural
Amlodipine is in preventing chest hypotension. Monitor more
used for the pain (angina) frequently when
treatment and resulting from additionalantihypertensives
prevention of coronary artery ordiuretics are added.
angina resulting spasm. Relaxing the
from coronary muscles lining the
spasm. arteries of the rest of Monitor heart rate; dose-
Amlodipine is also the body lowers the related palpitations
used in the blood pressure, which (morecommon in women)
treatment of high reduces the burden mayoccur
blood pressure on the heart as it
pumps blood to the
body
Name of Drug Indication Mechanism Of Action Contraindication Side effect / Nursing Consideration
adverse effect
citicoline Cerebrovascular Citicoline activates the hypertonia of the citicoline may Watch out for
Diseases, biosynthesis of parasympathetic exert a stimulating hypotensive effects
Classification: accelerates the structural action of the
Vitamins and recovery of phospholipids in the parasympathetic, Somazine must not be
Minerals consciousness and neuronal membrane, as well as a fleeting administered along with
overcoming motor increases cerebral and discrete medicaments containing
deficit metabolism and hypotensor effect
increases the level of
various
neurotransmitters,
including acetylcholine
and dopamine.
Citicoline has shown
neuroprotective
effects in situations of
hypoxia and ischemia.