DRUG STUDY

DRUG NAME ACTUAL DRUG ACTION INDICATION CONTRA- SIDE NURSING

DOSAGE INDICATIONS EFFECTS/ IMPLICATIONS
ADVERSE
EFFECTS
Generic Name: 1 amp Blocks dopamine Prevention of Contraindicated CNS: >Assess for nausea,
METOCLOPR- TIV receptors in chemotherapy in: >Restlessness vomiting, abdominal
AMIDE chemoreceptor induced emesis. >Hypersensitivity >Drowsiness distention, and bowel
trigger zone of >Possible GI >Fatigue sounds prior to and
Brand Names: the CNS. Management of obstruction or following
Clopra, esophageal hemorrhage. CV: administration.
Octamide, Stimulates reflux. >History of >Arrhythmias >Doses may be given
Reclomide, motility of the seizure disorders. slowly over 1-2
Reglan upper HI tract and >Parkinson’s GI: minutes. Rapid
accelerates gastric disease. >Constipation administration causes a
Classifications: emptying. >Diarrhea transient but intense
Antiemetic, GI >Nausea feeling of anxiety and
stimulant Therapeutic >Dry Mouth restlessness followed
Effects: by drowsiness.
>Decreased >Metoclopromide may
nausea and cause drowsiness.
Vomiting. Caution patient to
>Decreased avoid activities
symptoms of requiring alertness
gastric stasis. until response to
medication is known.
 DRUG STUDY

DRUG NAME ACTUAL DRUG ACTION INDICATION CONTRA- SIDE NURSING

DOSAGE INDICATIONS EFFECTS/ IMPLICATIONS
ADVERSE
EFFECTS
Generic Name: 1 amp Inhibits the >Acute GI, >Should not be CNS: >Monitor heart rate
HYOSCINE TIV muscarinic biliary and used in patients >Drowsiness periodically
N-BUTYL activity of genitourinary who have prior >Confusion throughout parenteral
BROMIDE acetylcholine. spasm, sensitivity to therapy.
including hyoscine n-butyl EENT: >Caution patient to
Brand Name: Corrects the biliary and renal bromide or any >Blurred vision avoid activities
Buscopan imbalance of colic. component of >Photophobia requiring alertness
acetylcholine and >An aid in buscopan. until response to
Classification: norepinephrine in diagnostic and >Untreated CV: medication is known.
Antispasmodic the CNS, which therapeutic narrow-angle >Palpitations >Advise patient to
may be procedures (e.g. glaucoma, >Tachycardia avoid concurrent use
responsible for gastroduodenal prostate of alcohol and other
motion sickness. endoscopy, hypertrophy w/ GI: CNS depressants with
radiology). urinary retention, >Dry mouth the medication.
Therapeutic mechanical >Constipation
Effects: stenosis in the
>Reduction of GIT, tachycardia, GU:
nausea and megacolon, and >Urinary
vomiting. myasthenia hesitancy
>Preoperative gravis. >Urinary
amnesia and retention
decreased
secretions. Derm:
>Decreased
Sweating
 DRUG STUDY

DRUG NAME ACTUAL DRUG ACTION INDICATION CONTRA- SIDE NURSING

DOSAGE INDICATIONS EFFECTS/ IMPLICATIONS
ADVERSE
EFFECTS
Generic Name: 5 mg IV Direct-acting In combination Contraindicated CNS: >Monitor blood
HYDRALAZI- peripheral with a diuretic in: >Head ache pressure and pulse rate
NE arteriolar in the >Hypersensitivity >Dizziness frequently during
vasodilator. management of >Drowsiness initial dosage
Brand Name: moderate to adjustment and
Apresoline Therapeutic severe CV: periodically
effects: hypertension. >Tachycardia throughout course of
Classification: >Lowering blood >Orthostatic therapy. Notify
Antihypertensive pressure in hypotension physician of
hypertensive significant changes.
patients and GI: >Encourage patient to
decreased >Nausea comply with additional
afterload in >Vomiting interventions for
patients with >Diarrhea hypertension (low
congestive heart sodium diet, smoking
failure. Derm: cessation, regular
>Rashes exercise, and stress
management).
 DRUG STUDY

DRUG NAME ACTUAL DRUG ACTION INDICATION CONTRA- SIDE NURSING

DOSAGE INDICATIONS EFFECTS/ IMPLICATIONS
ADVERSE
EFFECTS
Generic Name: 250 Stimulates CNS Used in Contraindicated CNS: >Monitor Blood
METHYLDOPA mg/tab, alpha-adrenergic combination in: >Sedation Pressure and pulse
1 tab TID receptors, with other >Hypersensitivity >Depression frequently during
Brand Name: producing a antihypertensiv >Active liver initial dosage
Aldomet decrease in es in the disease EENT: adjustment and
sympathetic management of >Some products >Nasal periodically
Classification: outflow to heart, moderate to containing Stuffiness throughout course of
Antihypertensive kidneys and blood severe alcohol or therapy. Notify
vessels. Result is hypertension. bisulfites and CV: physician or other
decreased blood should be avoided >Orthostatic health care provider of
pressure and in patients with hypotension significant changes.
peripheral known >Bradycardia > Encourage patient to
resistance, a intolerance. >Edema comply with additional
slight decrease in interventions for
heart rate, and no GI: hypertension (low
change in cardiac >Diarrhea sodium diet, smoking
output. >Dry mouth cessation, regular
exercise, and stress
Therapeutic management).
Effect:
>Lowering of
blood pressure.
 DRUG STUDY

DRUG NAME ACTUAL DRUG ACTION INDICATION CONTRA- SIDE NURSING

DOSAGE INDICATIONS EFFECTS/ IMPLICATIONS
ADVERSE
EFFECTS
Generic Name: 4g IV Essential for the Treatment and Contraindicated CNS: >Monitor pulse, blood
MAGNESIUM activity of many prevention of in: >Drowsiness pressure, respirations
SULFATE enzymes. hypomagnesemi >Hypermagnesem and ECG frequently
a. As an ia Resp: throughout
Classification: Play an important anticonvulsant >Hypocalcemia >Decreased administration.
Anticonvulsant role in in severe >Anuria respiratory rate >Monitor neurologic
neurotransmission eclampsia or >Heart block status before and
and muscular pre-eclampsia. CV: throughout course of
excitability. >Bradycardia therapy.
>Arrhythmias >When given for
Therapeutic >Hypotension hypomagnesemia, may
Effect: dilute 5g in 1000ml of
>Resolution of GI: D5W, 0.9% NaCl or
Eclampsia >Diarrhea Lactated Ringer’s
Solution.
 DRUG STUDY

DRUG NAME ACTUAL DRUG ACTION INDICATION CONTRA- SIDE NURSING

DOSAGE INDICATIONS EFFECTS/ IMPLICATIONS
ADVERSE
EFFECTS
Generic Name: 10 mg IV Binds to opiate Management of Contraindicated CNS: >Assess type, location
NALBUPHINE receptors in the moderate to in: >Sedation and intensity of pain.
CNS. severe pain. >Hypersensitivity >Head ache >Assess blood
Brand Name: to nalbuphine or >Dizziness pressure, pulse and
Nubain Alters the Also used as an bisulfites >Vertigo respirations before and
perception of and analgesic during >Patients who are periodically during
Classification: response to labor, as a physically EENT: administration. If
Opioid Analgesic painful stimuli, sedative prior to dependent on >Blurred Vision respiratory rate is
while producing surgery, and as opioid analgesics <10/min, assess level
generalized CNS a supplement in and have not been Resp: of sedation.
depression. balanced detoxified (may >Respiratory >Administer slowly,
anaesthesia. precipitate depression each 10mg over 3-5
In addition, it has withdrawal). minutes.
partial antagonist CV: >Advise patient to call
properties, which >Orthostatic assistance when
may result in hypotension ambulating or other
opioid withdrawal >Palpitations activities requiring
in physically alertness until response
dependent GI: to medication is
patients. >Nausea known.
>Vomiting >Caution patient to
Therapeutic make position changes
Effect: Derm: slowly to minimize
>Decrease in >Sweaty orthostatic
moderate to >Clammy hypotension.
severe pain. feeling
 DRUG STUDY

DRUG NAME ACTUAL DRUG ACTION INDICATION CONTRA- SIDE NURSING

DOSAGE INDICATIONS EFFECTS/ IMPLICATIONS
ADVERSE
EFFECTS
Generic Name: 25 mg IV Acts at many Used to produce Contraindicated CNS: >Monitor blood
MIDAZOLAM levels of the CNS sedation in: >Headache pressure, pulse and
to produce preoperatively >Hypersensitivity >Drowsiness respiration
Brand Name: generalized CNS and amnesia >Cross-sensitivity continuously
Versed depression. postoperatively. with other EENT: throughout IV
benzodiazepines >Blurred vision administration.
Classification: Effects may be To aid in the may exist >Administer each dose
Sedative/ mediated by induction of >Shock Resp: slowly over at least 2
Hypnotic gamma anaesthesia. >Comatose >Coughing minutes. Monitor IV
aminobutyric patients or those >Bronchospasm site closely to avoid
acid, an inhibitory Provides with pre-existing >Respiratory extravasation.
neurotransmitter. conscious CNS depression Depression >Inform patient that
sedation before >Uncontrolled this will decrease
Therapeutic diagnostic or severe pain CV: mental recall of the
Effect: radiographic >Arrhythmias procedure.
>Short-term procedures. >Medication may
sedation GI: cause drowsiness or
>Post-operative >Nausea dizziness. Advise
Anaesthesia patient to request
Local: assistance prior to
>Phlebitis at IV ambulation and
site transfer or other
activities requiring
alertness for 24 hours
following
administration.
 DRUG STUDY

DRUG NAME ACTUAL DRUG ACTION INDICATION CONTRA- SIDE NURSING

DOSAGE INDICATIONS EFFECTS/ IMPLICATIONS
ADVERSE
EFFECTS
Generic Name: 10 units Stimulates uterine Induction of Contraindicated CNS: >Assess character,
OXYTOCIN smooth muscle labor at term. in: >Maternal – frequency, and
producing uterine >Hypersensitivity seizures duration of uterine
Brand Name: contractions Facilitation of contractions; resting
Pitocin, similar to those in uterine CV: uterine tone; and fetal
Syntocinon spontaneous contractions at >Maternal – heart rate frequently
labor. term. hypotension throughout
Classification: >Fetal – administration. If
Hormone Stimulates in Facilitation of arrhythmias contractions occur
(Oxytocic) mammary gland threatened <2min. apart and are
smooth muscle, abortion. Resp: >50-65mmHg on
facilitating >Fetal – monitor, if they last
lactation. Postpartum hypoxia 60-90sec. or longer, or
control of if a significant change
Therapeutic bleeding after in fetal heart rate
Effect: expulsion of the develops, stop infusion
>Induction of placenta. and turn patient on her
labor left side to prevent
>Milk letdown Intranasal: Used fetal anoxia. Notify
to promote milk physician or other
letdown in health care provider
lactating immediately.
women. >Monitor maternal
blood pressure and
pulse frequently and
the fetal heart rate
continuously.
 DRUG STUDY

DRUG NAME ACTUAL DRUG ACTION INDICATION CONTRA- SIDE NURSING

DOSAGE INDICATIONS EFFECTS/ IMPLICATIONS
ADVERSE
EFFECTS
Generic Name: 1.5 g IV Binds to bacterial Treatment of Contraindicated CNS: >Before initiating
CEPHALOSP- cell wall the following in: >Seizures therapy, obtain a
ORINS – 2ND membrane, infections due >Hypersensitivity history to determine
Generation, causing death. to susceptible to cephalosporins GI: previous use of and
CEFUROXIME organisms: >Serious >Nausea reactions to penicillins
Therapeutic >Respiratory hypersensitivity >Vomiting or cephalosporins.
Brand Name: Effect: Tract Infections to penicillins >Diarrhea >Change IV sites
Ceftin, Kefurox, >Bactericidal >Skin and skin every 48-72 hours to
Zinacef action against structure Derm: prevent phlebitis.
susceptible infections >Rashes Monitor site
Classification: bacteria. >Bone and joint frequently.
Anti-infective infections Local:
(second >Urinary tract >Phlebitis at IV
generation and gynecologic site
cephalosphorins) infection
 DRUG STUDY

DRUG NAME ACTUAL DRUG ACTION INDICATION CONTRA- SIDE NURSING

DOSAGE INDICATIONS EFFECTS/ IMPLICATIONS
ADVERSE
EFFECTS
Generic Name: 30mg IV Inhibits Short-term Contraindicated CNS: >Assess pain prior to
KETOROLAC q8° x 4 prostaglandin management of in: >Drowsiness and 1-2hr following
doses synthesis pain (not to >Hypersensitivity >Dizziness administration.
Brand Name: producing excedd 5 days >Cross-sensitivity >Administration in
Toradol peripherally total for all with other EENT: higher than
mediated routes NSAIDS may >Abnormal recommended doses
Classification: analgesia. combined). exist vision does not provide
Nonopioid >Known alcohol increased effectiveness
analgesic, Also has intolerance Resp: but may cause
Nonsteroidal antipyretic and >Dyspnea increased side effects.
anti- anti-inflammatory >Asthma Duration of ketorolac
inflammatory properties. therapy, by all routes
agent GI: combined, should not
Therapeutic >Nausea exceed 5 days.
Effects: >Dyspepsia >Advise patient to
>Decreased pain. avoid the concurrent
GU: use of alcohol, aspirin,
>Urinary naproxen, ketoprofen,
Frequency acetaminophen or
other OTC
Local: medications without
>Injection site consultation with
pain. physician, pharmacist
or other healthcare
provider.
 DRUG STUDY

DRUG NAME ACTUAL DRUG ACTION INDICATION CONTRA- SIDE NURSING

DOSAGE INDICATIONS EFFECTS/ IMPLICATIONS
ADVERSE
EFFECTS
Generic Name: Directly Prevention and Contraindicated CNS: >Monitor blood
METHYLER- stimulates uterine treatment of in: >Dizziness pressure, heart rate,
GONOVINE and vascular postpartum or >Hypersensitivity >Headache and uterine response
smooth muscle. postabortion >Should not be frequently during
Brand Name: hemorrhage used to induce Resp: medication
Methergine Therapeutic caused by labor. >Dyspnea administration.
Effect: uterine atony or >Advice patient that
Classification: >Uterine subinvolution. CV: medication may cause
Oxytocic Contraction >Palpitations menstrual-like cramps.
>Chest pain >Caution patient to
>Arrhythmias avoid smoking, as
nicotine constricts
GI: blood vessels.
>Nausea
>Vomiting

GU:
>Cramps
 DRUG STUDY

DRUG NAME ACTUAL DRUG ACTION INDICATION CONTRA- SIDE NURSING

DOSAGE INDICATIONS EFFECTS/ IMPLICATIONS
ADVERSE
EFFECTS
Generic Name: 50g BID Block stimulation Alone or in Contraindicated CNS: >Monitor blood
BETA- of beta adrenergic combination in: >Fatigue pressure, ECG, and
ADRENERGIC receptors. Do not with other >Uncompensated >Weakness pulse frequently during
BLOCKING usually affect agents in the congestive heart dosage adjustment
AGENTS, beta2 receptor management of failure EENT: period and periodically
METOPROLOL sites. hypertension. >Pulmonary >Blurred Vision throughout therapy.
edema >Stuffy Nose >Vital signs should be
Brand Name: Therapeutic >Cardiogenic monitored every 5-15
Betaloc, Effect: shock CV: min. during and for
Lopresspr, >Decreased blood >Bradycardia or >Bradycardia several hours after
Toprol pressure heart block >Hypotension parenteral
>Decreased >Known alcohol administration. If <40
Classification: frequency of intolerance GI: bpm, especially if
Antihypertensive, attacks of angina >Nausea cardiac output is also
Antianginal, pectoris >Vomiting decreased, administer
Antiarrhythmic >Slowing of atropine 0.25-0.5mg
ventricular Derm: IV (with the
response. >Rashes physician’s
prescription).
>Advise patient to
make position changes
slowly to minimize
orthostatic
hypotension.
 DRUG STUDY

DRUG NAME ACTUAL DRUG ACTION INDICATION CONTRA- SIDE NURSING

DOSAGE INDICATIONS EFFECTS/ IMPLICATIONS
ADVERSE
EFFECTS
Generic Name: 1 tab OD An essential Prevention and Contraindicated CNS: >Assess patient’s
IRON x 4 doses mineral found in treatment of in: >Head ache nutritional status and
SUPPLEMENT, hemoglobin, iron deficiency >Primary >Dizziness dietary history to
FERROUS myoglobin, and a anemia. hemochromatosis determine possible
SULFATE number of >Hemolytic CV: cause of anemia and
enzymes. anemias and other >Hypotension need for patient
Brand Name: anemias not due >Tachycardia teaching.
Feosol, Parenteral iron to iron deficiency. >Encourage patient to
Ferospace, Fer- enters the GI: comply with
In-Sol, Fer-Iron, bloodstream and >Nausea medication regimen.
Fero-Gradumet, organs of the >Constipation Do not double doses, if
Ferralyn reticuloendotheli- >Dark stools a dose is missed.
al system (liver, >Epigastric pain >Advise patient that
Classification: spleen, bone stools may become
Antianemics marrow), where dark green or black
iron is separated and that this change is
from the dextran harmless.
complex and
becomes part of
the body’s iron
stores.

Therapeutic
Effect:
>Prevention and
treatment of iron
deficiency.
 DRUG STUDY

DRUG NAME ACTUAL DRUG ACTION INDICATION CONTRA- SIDE NURSING

DOSAGE INDICATIONS EFFECTS/ IMPLICATIONS
ADVERSE
EFFECTS
Generic Name: 500mg/ Binds to bacterial Treatment of Contraindicated CNS: >Before initiating
CEPHALOSP- Cap cell wall the following in: >Seizures therapy, obtain a
ORINS – 1st 1 cap q6° membrane, infections due >Hypersensitivity history to determine
Generation, causing death. to susceptible to cephalosporins GI: previous use of and
CEPHALEXIN organisms: >Serious >Nausea reactions to penicillins
Therapeutic >Skin and skin hypersensitivity >Vomiting or cephalosporins.
Brand Name: Effect: structure to penicillins >Diarrhea >Instruct the patient to
Biocef, Cefanex, >Bactericidal infections take medication
C-Lexin, Keflex, action against >Pneumonia Derm: around the clock at
Keftab susceptible >Otitis media >Rashes evenly spaced times
bacteria. >Septicemia and to finish the
Classification: >Bone and joint Local: medication completely
Anti-infective infections >Phlebitis at IV as directed, even if
(first generation >Urinary tract site feeling better.
cephalosporins) and gynecologic >Instruct the patient to
infection notify physician if
fever and diarrhea
develop, especially if
diarrhea contains
blood, mucus or pus.
DRUG STUDY