Haley R. Lamont
Abstract
This paper takes an in depth analysis of Neonatal Abstinence Syndrome, beginning with an
overview of the issue and the issue of drug dependency itself. This includes the types of drugs
most commonly found to cause NAS and the number of children born each year who are
diagnosed with NAS. Next there is an analysis of Neonatal Abstinence Syndrome that includes
how the syndrome is developed, the effects of different drugs on infants, and the treatment
options for infants. In addition to fetal drug dependency, this paper covers maternal addiction.
Including treatment options for pregnant and drug addicted mothers, legislation against addicted
mothers, and the number of cases reported by doctors versus the number of cases in reality. After
the coverage of maternal addiction, there are 3 legal pieces, including one court case and two
acts. Of the two acts, one has been has been passed by only the House of Representatives, while
the other is an amendment to a previous act made in 2011. There is then a comparison of laws
both state wise and internationally, including places like Tennessee and the United Kingdom.
The paper closes with an interview with Dr. Hendree Jones, a professor and expert on Neonatal
Abstinence Syndrome, in which treatment centers and programs, severity of drugs, opinions on
punishment, and connotation of the word “addiction” is covered. In conclusion, the author does a
final analysis of the causes and effects of Neonatal Abstinence Syndrome and its lack of
treatment options.
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Every 19 minutes. Every 19 minutes a drug dependent baby is born. Every 19 minutes a
case of Neonatal Abstinence Syndrome is discovered. To make the matter worse, there are
currently 36 states that don’t have a law requiring doctors to report these cases (Barletta, 2016).
Although this is a very apparent issue, doctors are still very unsure about a lot of the data
surrounding it because of the lack of scientific investigation. In addition to doctors, many people
are unaware of not only the effects of maternal drug use but also what Neonatal Abstinence
Syndrome is in general. This then creates the issue of discovering treatments for both the mother
and child because in a community of people very few know of the syndrome. And with little
knowledge comes very few treatment options which would explain why there are not very many
pregnancy centers in the United States that willingly accept drug addicted mothers, and
therefore, most of the women never seek further treatment (H. Jones, Personal communication,
October 26, 2017). The lack of proper treatment centers for women who are both pregnant and
abuse drugs generates an increases in children born with drug dependency by limiting the
Types of Drugs
develop an addiction. The only difference the drugs have on a child are the effects or severity of
the dependency they have. There are also factors of when in the pregnancy the drugs are used
and how frequently the drugs are used. According to Dr. Hendree Jones, who is later referenced
for an interview, the most important things to figure out when a woman comes to a rehab facility
are what drug they are taking, when in their pregnancy they have taken it, and how frequently the
EVERY 19 MINUTES 4
drug is used (H. Jones, Personal communication, October 26, 2017). These three pieces of
information make it possible for doctors to be able to form a treatment plan, with the hopes of
bringing the maternal addiction to an end and prevent severe effects on the infant.
Number of Babies
Over the years, the amount of children born with a drug dependency has increased so
intensively that treatment centers are a necessity now. This is especially prevalent in Penn State’s
Hospital where they alone get at least 20 newborns every year born with a dependency caused by
the mother. The Penn State Hospital says that, “An estimated 1 in 200 babies in the United
States are born dependent on an opioid drug.” Out of those children, a majority of them are cared
for in a NICU until the infant becomes stable. Over 2000 babies were cared for in the NICUs in
Pennsylvania in 2016 due to condition brought on by mother’s substance abuse (Wenner, 2017).
Development
Through recent studies the cause of Neonatal Abstinence Syndrome has become more
apparent and the illness itself has more of a definition. Doctors have established that the narcotic
or substance the mother is using or abusing travels through the mother’s blood stream and to the
fetus’ placenta ("Neonatal Abstinence Syndrome," n.d.). The most current definition of NAS
(Neonatal Abstinence Syndrome) is “a group of conditions caused when a baby withdraws from
certain drugs he’s exposed to in the womb before birth” ("Neonatal Abstinence Syndrome
(NAS)," 2017). The development of NAS is most commonly from the misuse of prescribed legal
drugs or from the use of illegal drugs such as opioids (Botticelli, 2015).
In addition to withdrawal, the baby could have poor intrauterine growth, premature birth,
seizures, and birth defects. Heroin and other opiates can cause withdrawal and seizures that can
last anywhere from 4 to 6 months, while amphetamines are associated with low birthweight and
premature birth. Cocaine use can coordinate with poor fetal growth, developmental delay,
learning disabilities, and lower IQ, and marijuana creates lower birth weights. Alcohol slows
down growth and puts the children at risks for birth defects in comparison to cigarette smoking
which can lead to smaller babies or even a stillbirth. Although every drug effects the infant
differently, they all still have a negative effect on the body and could, if heavily abused, result in
There is specific treatment plans for NAS dependent on the newborn’s weight and status
Children’s Hospital, the treatment for both minor and severe NAS are presented. In minor cases,
in which the child is simply irritable, the use of swaddling or snuggling children to comfort them
is frequently used. It is also extremely common that because the child’s body is more active from
the drug, the infant needs a higher calorie intake, and therefore will be given a formula with
more calories. The cases of severe dehydration are met with giving the child intravenous fluids.
The more severe cases of NAS, frequently including seizures, are treated with specific drugs. For
NAS related to heroin and opiates, the drug methadone is used, while alcohol dependency is
treated with benzodiazepines. In any treatment involving specific drugs, the treatment drug is
most likely from the same family as the drug the child is dependent on ("Treatments for Neonatal
Maternal Addiction
EVERY 19 MINUTES 6
Treatment with methadone is and has been the standard of care for pregnant women since
1998. Although after recent studies, there is a possibility that buprenorphine could be a better
option. The use of buprenorphine instead of methadone results in not only a 10 percent lower
chance of NAS but also a shorter neonatal treatment time by an average of 8.4 days. In addition
to that, the infant is more likely to be born with a higher gestational age, weight, and head
circumference. The same study found that women who do divided treatments of methadone and
buprenorphine, instead of pure and constant methadone, are shown to have less of a chance of
having a child born with NAS (Abuse, n.d.). There are many factors that contribute to the
selection of treatment method for the addicted mothers. This factors include but are not limited
to: the substance that has been used, the level of abuse, and the mother’s health and psychiatric
history ("Drug & Alcohol Rehab Centers for Pregnant Women," n.d.).
Currently, Tennessee is the only state to have a law specifically addressing drug abuse in
pregnancy being a crime. While in other states like Iowa, health care providers require test and a
report of prenatal drug use. States like Virginia consider neonatal drug use as to be included in
child welfare laws. This means that proper evidence of neonatal drug use can be used in a court
of law to terminate parental rights on the grounds of child abuse or neglect. Although a majority
of states feel it is against the wellbeing of the infant, it is hard to prosecute mothers because of
the lack of inclusion of fetuses in most United States or state laws ("Using Illegal Drugs During
Pregnancy," 2016).
Although reporting an incident of maternal addiction may seem like the common thing to
do among health professionals, that is not the case in most states. There are currently 15 states in
the United States that require a health professional to report if there is evidence that the patient is
pregnant and abusing drugs (Miranda, Dixon, & Reyes, 2015). This poses the question as to why
there are not more states who require the report when there are 24 states and the District of
Columbia who consider maternal drug use as child abuse ("Substance Use During Pregnancy,"
2017).
Over the span of 12 years (2000-2012) in the United States, the number of infants born
with NAS has increased fivefold. This statistic draws attention from Congress to draft laws to
benefit both the mother and the child. The purpose of the Protecting Our Infants Act of 2015 is to
help identify evidence-based approaches to care for these babies and their mothers. This act
would require the United States Department of Health and Human Services to conduct a study
and develop recommendations for preventing and treating prenatal opioid use disorders and
NAS. This would be done with the assistance of the Centers for Disease Control and Prevention
to improve the availability and quality of data collection related to NAS. All of this with the end
goal of ensuring that all pregnant women have access to proper prenatal care and safety is
provided for mothers and their babies. Proper prenatal care is the primary focus due to the fact
that two thirds of women struggling with drug abuse do not receive the standard of care for
An act similar to the Protecting Our Infants Act of 2015 is the 2011 Prescription Drug Abuse
Action Plan which was never passed by both branches of Congress. Even with the Protecting Our
EVERY 19 MINUTES 8
Infants Act of 2015 in effect, there are only a few states in the U.S. that have prescription drug
monitoring programs. If more states implement drug monitoring programs, the goal is that the
Substance Abuse and Mental Health Services Administration will be able to create a connection
The main focus of the Infant Plan of Safe Care Improvement Act is to amend the Child
Abuse Prevention and Treatment Act, requiring certain monitoring and oversight on mothers and
their affected infants. Each infant in the program would have their own personalized treatment to
best ensure their success after leaving medical care. In addition to this, states would be required
to report the number of infants with personalized care each year and whether or not treatment
was initiated in respect to family life and maternal drug use. To enforce the act, the Department
of Health and Human Services would be required to monitor the compliance of states that
receive grants and know the relevant current laws and required state policies and procedures
regarding the care of drug affected babies. The heaviest impact of the Infant Plan of Safe Care
Improvement Act would be to move state health policies towards the federal regulations. As of
May 2016, the act has been passed the House of Representatives and is awaiting a Senate vote
(Barletta, 2016).
The case of the Commonwealth of Kentucky v Welch was taken to the Kentucky Supreme
Court in 1993. The matter was regarding Connie Welch due to the fact that she was found
injecting oxycodone into her jugular vein while eight months pregnant in 1989. She was given a
court date instead of going directly to jail because of her condition. When the baby was born in
later in 1989, he had no birth defects and no signs of long term effects, but he was placed in the
EVERY 19 MINUTES 9
NICU because he showed the main symptoms of Neonatal Abstinence Syndrome. Early in 1990,
in Welch’s county, she was charged with abuse, possession of a narcotic, and possession of
paraphernalia. In May of 1990, Welch was found guilty of all three offenses and was sentenced
to a total of 8 years in prison. Later that year in the Court of Appeals, the judges affirmed the
drug charges and vacated the abuse charge. Welch’s attorney made the points that under certain
precedents a fetus is not a person and that the way the court was using the precedent was not how
they were intended to be used. The majority opinion of the court states that the legal issue of
abuse was not found in the case because of the way the precedent defines a human being. To
change this precedent for future cases, the Kentucky Supreme Court rewrote the statute defining
The number of babies born with NAS in Tennessee had increased fifteenfold in the last
ten years. In 2014 the state government passed a law to “allow women who give birth to babies
‘harmed by’ illegal drug usage to be charged with misdemeanor assault.” Tennessee is the first
state to create a specific law to make it a crime for women who give birth to drug dependent
children. The law has made women afraid to get treatment in light of getting arrested down the
road. In 2015, 30 were arrested in Tennessee with only one serving jail time. This issue is
pressing because taking any kind of painkiller or antidepressant prescribed by a doctor gives the
baby 50% chance of being born with NAS. The problem is that there are not enough detox
treatment options available for pregnant women in the state of Tennessee. Methadone programs
in Tennessee do not accept Tennessee's version of Medicaid, and therefore, there are little to no
EVERY 19 MINUTES 10
treatment options for women in the state, and then the women are stuck in a legal issue as well as
a medical issue ("The Ill Effects of Tennessee's New Drug Law," 2015).
Dr. Hendree Jones, of UNC Chapel Hill, has published an assortment of articles and
studies on NAS and the treatment problem for mothers. In an interview with her she mentioned
that the NAS patients and drug addicted mothers in different countries have so many similarities
and that the legal policies in different places have the biggest effects on the patients. Most
importantly the use of a medical approach works more efficiently. Dr. Jones’ most important
message is that, “The process of engaging people and offering them help them is universal. Even
if some places are more punitive than the United States, the goal is to help, to do whatever we
Published in the British Medical Journal, Rishi J Desai et al, worked together on an
observational study entitled “Exposure to prescription opioid analgesics in utero and risk of
neonatal abstinence syndrome.” The study observed pregnant women who were actively taking
at least one prescription opioid drug. They then assessed the time period in which the opioids
were being taken, including both the duration of the drug use as well as the time period in the
pregnancy. The purpose of the study was to try and make a correlation between the type of
opioid use and the diagnosis of Neonatal Abstinence Syndrome. In order to gather people for the
observational study, the Medicaid Analytical extract files were pulled from the years 2000 to
2007. The study showed that drugs such as heroin give the most obvious signs of NAS, while
drugs such as cocaine give the most severe symptoms. The total number of women included in
the study was 290,605 and of those women, nearly half of them had misused at least one harmful
EVERY 19 MINUTES 11
drug during the course of their pregnancy. Of the total amount of women in the study (290,605)
there were 1,705 cases of NAS identified. From this the researchers found the risk factors of each
individual group based on their drug of choice and duration period to find which groups had the
highest risk factor for their child to develop NAS (Desai et al., 2015).
UNC Horizons
psychiatry at Johns Hopkins, and the executive director of UNC Horizons, she discussed the
importance of effective treatment on pregnant women who are also addicted to drugs. Dr. Jones
has done research and published over 175 publications on NAS and drug addiction in pregnant
women. Her most current project is UNC Horizons, defined by the University’s Medical School
as, “a substance use disorder treatment program for pregnant and/or parenting women and their
children, including those whose lives have been touched by abuse and violence” ("UNC
Horizons Program," 2017). The mission of UNC Horizons, according to Dr. Jones, is to improve
health and wellbeing the lives of children and women with drug addiction.
The interview initially talked about Dr. Jones’ current study and mission to increase the
pregnancies amongst drug using women and women in general. This mission was sparked by a
study Dr. Jones was reading about in which the statistics said that 86 percent of women who use
drugs have an unplanned pregnancy. Dr. Jones wanted to find out the specifics on the number of
women who have tried drug treatment programs and how that affected their pregnancy. The
answer to that problem was found in a mother study by the New England Journal of Medicine on
EVERY 19 MINUTES 12
methadone treatment comparison. This study states that women who give birth to children that
are drug dependent have tried drug treatment 3 times prior to giving birth. Those same women
reported that the treatment type was not working for them or that the drug treatment center could
not treat them specifically because they were pregnant (H. Jones, Personal communication,
When asked to rank or determine the severity of the most common drugs on children, Dr.
Jones was able to provide the symptoms for each substance. Alcohol is said to be the most severe
simply because the short and long term effects are unknown. It is yet to be known the exact
effects alcohol has on infants because it affects every infant differently and therefore is the most
risky substance to abuse while carrying a child. Second is tobacco because of the long term
effects. The primary effects being negative neurobehavioral outcomes, such as the compromising
of the development of neural passages to the brain, obesity due to being born with a low birth
weight, and the later development of type 2 diabetes (Bruin, Gerstein, & Holloway, 2010). Third
is risk factor drugs like cocaine because of short term effects such as behavior problems and
trouble with early childhood education (Villa, 2017). Finally opioids are ranked last because the
When talking about legislation and the punishment of women who give birth to drug
dependent babies, Dr. Jones stated that punishment is ineffective and only leads to less cases
being diagnosed and treated. Dr. Jones feels that it is a bad idea to punish mothers of NAS
affected babies because the government cannot legislate their way out of social issues. The issue
of drug addiction must be treated as a public health issue, and funds need to be there to do
EVERY 19 MINUTES 13
research and to train other health professionals on the topic. At UNC Horizons Program, the
treatment methods that work best are birth methadone for opioid patients and monetary rewards
for women who stay drug free and behavioral therapy. The motto in the program is that patients
have “a pocket full of skills not a pocket full of pills” (H. Jones, Personal communication,
The last topic of discussion, that Dr. Jones was most passionate about, was the
connotation of the word addict when used to describe children with Neonatal Abstinence
Syndrome. This is because according to the definition of an addict, a child is incapable of being
“addicted.” A child, especially an infant, can be only dependent on drugs because they cannot
consent to the use of the addictive substance. Dr. Jones heavily emphasized the negative
connotation that referring to infants as addicts gives, simply because the child was unable to
make the decision that led to their current condition and because it is incorrect to the definition
of an addict.
Conclusion
In an evaluation of the effects neonatal drug dependency has, not only on the infant but
on the mother as well, it is apparent that one of the main causes is the lack of proper treatment
for pregnant women who are addicted to drugs. Not only are there not enough treatment options,
but there are also not enough treatment methods to work for these women without further
endangering their infants. Though there are many different ways a child can be born with
symptoms of defects, there is only one way an infant can become dependent on drugs and that is
through their mother’s use. Education is the number one cause of this problem or in this case
lack of education. Most women have never been educated on the effects drugs have on children,
EVERY 19 MINUTES 14
the effects drugs have on them or the importance of practicing the use contraceptives. Many of
these women who have a child born with Neonatal Abstinence Syndrome are experiencing an
unplanned pregnancy and are already addicted to drugs. In addition to education, the study of
new treatments for Neonatal Abstinence Syndrome needs to be frontiered. There are currently
only two drugs that are FDA approved to treat signs and symptoms of a drug dependency in
infants. This meaning that although methadone and buprenorphine are used to treat women and
infants, that is yet another drug that, with medical assistance, they will have to be slowly taken
off of. But unfortunately, there are very few facilities that will treat women who are both
pregnant and addicted to drugs because of the uncertainty of the child’s outcome and the worry
that these women will use drugs again after the child’s birth. It is for that reason that it is most
apparent that the lack of proper treatment centers for women who are both pregnant and abuse
drugs generates an increases in children born with drug dependency by limiting the possibility of
addiction detection. When women don’t reach out for help or when facilities refuse to treat, it
creates a large amount of neglect for the child’s health and wellbeing and eventually could lead
to legal repercussions. It is for this reason that education, better facilities, and more drug research
are necessary to stop the exponential growth of children each year being born not only with
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