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DAFTAR ISI

Halaman
Daftar Isi .................................................................................................... i
Daftar Singkatan ....................................................................................... ii

BAB I PENDAHULUAN
Pendahuluan ................................................................................................ 1

BAB II TINJAUAN PUSTAKA


2.1 Definisi ................................................................................................. 3
2.2 Etiologi ................................................................................................. 3
2.3 Epidemiologi ........................................................................................ 4
2.4 Penularan .............................................................................................. 5
2.5 Patogenesis ........................................................................................... 7
2.6 Gambaran Klinis .................................................................................. 13
2.7 Diagnosis .............................................................................................. 18
2.8 Diagnosis Banding .............................................................................. 24
2.9 Tata Laksana ........................................................................................ 24
2.10 Kemoprofilaksis .................................................................................. 26
2.11 Komplikasi .......................................................................................... 27
2.12 Prognosis ............................................................................................. 27
2.13 Pencegahan .......................................................................................... 28

BAB III KESIMPULAN


Kesimpulan ................................................................................................. 29

DAFTAR PUSTAKA ................................................................................ 30

i
Daftar Singkatan

AKI Acute kidney injury


ALI Acute lung injury
ALT Alanine aminotransaminase
AP-1 Activator protein 1
ARDS Acute respiratory distress syndrom
AST Aspartat transaminase
ATP Adenosine trifosfat
BUN Blood urea Nitrogen
CBC Complete blood count
CCK Creatinin fosfokinase
CD Cluster of differentiation
CFT Complement fixation test
CIE Counter immune electrophoresis
CPK‐MM Creatine phopokinase muscle
CSS Cairan serebro spinal
DGM Dark-ground Microscope
DNA Deoxy ribonucleic acid
ELISA Enzyme linked immunosorbant assay
ERK Extracellular signal regulated kinase
GLP Glicoprotein
IFAT Indirect Fluorescent antibody test
IHA Indirect haemagglutination test
IL Interleukin
ILS International leptospirosis society
LPS Lipopolysacharida
MAPK Mitogen-activated protein kinase
MAT Microcapsule agglutination test
mRNA Messenger RNA
MSAT Macroscopic slide agglutination test
NEFA Nonesterified fatty acid
p38 Protein 38
PBMC Peripheral blood mononuclear cells
PCR Polymerase chain reaction
PSAT Patoc-slide agglutination test
PT Prothrombin time

ii
RDT Rapid diagnostic test
RNA Ribonucleic acid
rRNA Ribosomal RNA
SEL Sensitized erythrocyte lysis test
TLR Tool like receptor
TNF Tumor necrosis factor
WBC White blood cells

iii