ORIGINAL ARTICLE
Table 1: Demographic, Clinical and Functional Characteristics of motor and cognitive functions correspondingly (table 2). The
Rehabilitation Inpatients (Nⴝ491) mean acute and rehabilitation LOS were 14.2⫾11.4 (median,
Mean or Median or 25th–75th 11.0) and 30.8⫾16.3 (median, 29.0). Approximately 1 in 10
Characteristics Number of Percentage Percentile patients (91.4%) had at least 1 kind of comorbid condition.
Demographic characteristics Hypertension (79.2%), hyperlipidemia (54.8%), and diabetes
Age (y) 61.3 62.0 53–71 mellitus (36.1%) were the 3 most prevalent comorbid condi-
Sex, male 289 58.9 tions.
Ethnicity
Univariate Results
Chinese 405 82.5
Malay 45 9.2 We found that age, sex, ethnicity, and prestroke living ar-
Indian 24 4.9 rangement did not correlate significantly with median LOS.
Others 17 3.5 Although individual comorbid conditions were not signifi-
Prestroke living arrangement cantly associated with median LOS, having more than 3 co-
With immediate family 446 90.8 morbid conditions at admission was associated with a shorter
With nonimmediate family 15 3.1 LOS at 10% significance level (see table 2). Our findings
Alone 19 3.9 indicated a strong association between median LOS and the
Others 11 2.2 choice of hospital ward class, which also serves as a proxy for
Ward class socioeconomic status. The median rehabilitation LOS was also
Private (A, B1) 55 11.2 significantly longer for patients who had a longer acute hospital
Subsidized (B2, C) 436 88.8 stay (0 –11d vs ⱖ12d). Similar results were obtained when the
Comorbidity, any 449 91.4 data were analyzed with log transformation of LOS.
Hypertension 389 79.2 Among the clinical characteristics, the median LOS was
Hyperlipidemia 269 54.8 longer for patients diagnosed with hemorrhagic stroke and
Diabetes mellitus 177 36.1 inversely associated with both the FIM motor and cognitive
Previous stroke 90 18.4 scores. The site of the brain lesion and affected hemisphere
Ischemic heart disease 68 13.8 were not significantly associated with median LOS.
Atrial fibrillation 32 6.5
Congestive heart failure 11 2.2
Multivariate Results
Myocardial infarction 9 1.8 Table 3 shows that the significant factors predicting rehabil-
Valvular heart disease 6 1.2 itation LOS were the extent of patients’ dysfunction in physical
Clinical characteristics activity at admission (FIM motor score), ward class, prestroke
FIM motor score at admission 36.4 36.0 23–48 living arrangement, and medical comorbidity, with the fitted
FIM cognitive score at model explaining 46% of the variance in rehabilitation LOS.
admission 23.8 27.0 16–33 We ran diagnostic tests to ensure that assumptions of the
Type of stroke
Ischemic 345 70.3
Hemorrhagic 146 29.7 Table 2: Factors Significantly Associated With Rehabilitation LOS
Acute LOS (d) 14.2 11.0 7–17 by Univariate Analysis
Rehabilitation LOS (d) 30.8 29.0 21–38 N⫽491
Median
Characteristics No. % LOS (d) P*
Demographic characteristics
cally significant. All statistical tests were performed by using Ward class ⬍.001
the Statistical Package for Social Sciences, version 15.0.a Private (A, B1) 55 11.2 36
Subsidized (B2, C) 436 88.8 28
RESULTS Number of comorbid conditions .063
0–3 430 87.6 29
We retrieved a total of 525 case notes over a 21-month
⬎3 61 12.4 25
period from March 1, 2005, to December 31, 2006. We ex-
Clinical characteristics
cluded 3 patients diagnosed with traumatic intracerebral hem-
FIM motor score at admission ⬍.001
orrhage, 25 patients diagnosed with subarachnoid hemorrhage,
Severe: 13–25 140 28.5 40
and 2 patients with missing FIM scores at admission. Four
Moderate: 26–64 328 66.8 25
patients who were transferred to an acute care hospital during
Mild: 65–91 23 4.7 11
the period of rehabilitation stay were also excluded. In total, we
FIM cognitive score at admission ⬍.001
included 491 patients in the analysis.
Severe: 5–9 73 14.9 37
Patient Characteristics Moderate: 10–24 145 29.5 32
Mild: 25–35 273 55.6 25
As shown in table 1, the mean age of patients was 61.3 years
Type of stroke ⬍.001
(median; 62.0y), 58.9% were men, 82.5% were of Chinese
Ischemic 345 70.3 27
ethnicity, and 90.8% resided with their immediate family mem-
Hemorrhagic 146 29.7 31
bers. Of the patients, 70.3% were diagnosed with ischemic
Acute LOS (d) .001
stroke. Those choosing private or semiprivate wards were
0–11 267 54.4 27
11.2%. The mean motor and cognitive scores of the FIM at
ⱖ12 224 45.6 30
admission were 36.3⫾16.0 (median, 36.0) and 23.6⫾10.2 (me-
dian, 27.0), respectively. At admission, almost 95% and 44% *The Mann-Whitney U test or the Kruskal-Wallis test was used to
of the patients were moderately or severely impaired in their assess the differences between groups.
FIM motor score at admission ⫺.022 (0.001) ⫺0.647 (⫺.024 to ⫺0.020) ⬍.001
Ward class
Subsidized *
Private 0.200 (0.059) 3.410 (0.085–0.309) .001
Prestroke living with nonimmediate family
No *
Yes 0.281 (0.106) 0.089 (0.074–0.489) .008
No. of comorbid conditions at admission, ⬎3
No *
Yes ⫺0.177 (0.055) ⫺0.107 (⫺0.284 to ⫺0.068) .001
(Constant) 4.088 (0.047) (3.993–4.176) ⬍.001
NOTE. N⫽491. Adjusted R2⫽0.455. R2 is the percentage of total variance explained by the model. The following variables, in addition to the
reported (significant) variables, were entered into the model: stroke type, acute LOS, and FIM cognitive score at admission.
*Reference category.
ordinary least squares regression model were not violated. We for stroke patients. A similar relationship has been found in
found the log-scale residuals to be homoscedastic, which im- studies performed in inpatient rehabilitation settings in the
plied that the ordinary least-squares estimates with the logged United Kingdom34 and the United States.22 A Taiwanese study
dependent variable were unbiased.32 The Durbin-Watson sta- performed by Chung et al33 found the ability of stroke patients
tistic was 1.988, indicating that the model met the assumption to engage in self-care activities to have a major impact on the
of independence of the residual. Multicollinearity was also not rehabilitation LOS. Although others35,36 have reported cogni-
detected because the variance inflation factor for all indepen- tive dysfunction to complicate the rehabilitation process and to
dent variables was close to 1.0. When the standardized resid- prolong LOS, poor cognitive status did not independently in-
uals were plotted against a theoretic normal distribution in a crease the LOS in this study. Table 4 shows that the LOS was
probability-probability plot, the points formed an approximate determined predominantly by the FIM motor score regardless
straight line, which indicated normality of the standardized of the severity of cognitive dysfunction at admission. However,
residuals. both motor and cognitive status of patients should be taken into
The strongest predictor, after adjustment, was FIM motor account in the planning of care and the setting of rehabilitation
score at admission, which explained 43% of the LOS variation. goals. When catering to patients who are more cognitively
The smearing estimator of the fitted model was calculated to be impaired, more specialized rehabilitation efforts need to be
1.0806. After back-transforming the fitted values and multiply- committed. This has impact on the rehabilitation manpower
ing it by the smearing estimator, we found a 1-point increase in needed particularly as the population ages.
the admission FIM motor score to be associated with a 1.1-day As with other studies, age,23-25 stroke type, and lesion
decrease in the mean rehabilitation LOS (P⬍.001). The choice characteristics24 were not found to significantly influence LOS.
of private wards corresponded to a 1.3-day increase in LOS, The current evidence regarding the influence of individual
whereas we found residing with nonimmediate family mem- comorbid conditions is equivocal. Similar to the findings in
bers to be associated with a 1.4-day increase in LOS. Having other studies,19,21,24 we did not find diabetes mellitus and heart
more than 3 comorbid conditions at admission was signifi- disease to be significant prognostic variables. In this study,
cantly associated with a reduction in LOS by 1.3 days. individual medical comorbid conditions did not independently
After entering FIM motor score at admission into the model, influence LOS, but patients with more than 3 conditions had
we found stroke type, acute LOS, and FIM cognitive score at shorter LOS. Similar findings also draw attention to medical
admission not to be significantly associated with ln-LOS. We comorbidity as an indicator for rehabilitation potential with a
found patients with hemorrhagic stroke to have lower mean higher degree of comorbidity found to be prognostic of poorer
FIM motor scores compared with those with ischemic stroke rehabilitation outcomes.37 If we calculate rehabilitation effec-
(32.8 vs 38.4, P⬍.001). The mean FIM motor score was also tiveness, defined as actual functional improvement divided by
higher for patients with acute LOS of 11 days or less compared potential improvement ([discharge FIM score ⫺ admission
with those with LOS 12 days and above (38.5 vs 33.5, FIM score]/[maximum achievable FIM score ⫺ admission FIM
P⬍.001). Hence, the variable FIM motor score adequately score]), we find the mean rehabilitation effectiveness for pa-
captured and explained the impact of hemorrhagic stroke and tients with more than 3 comorbid conditions to be significantly
acute LOS on rehabilitation LOS.
DISCUSSION Table 4: Mean Rehabilitation LOS by FIM Motor and FIM
Cognitive Scores
Stroke rehabilitation will become more important as the
population ages. Hospital administrators and rehabilitation pro- LOS (d)
fessionals who are responsible for ensuring an efficient deliv- FIM Motor Score at Admission
ery and accessibility of rehabilitation services will need to FIM Cognitive Score
anticipate the resource needs of different patients. There is at Admission 13–25 26–64 65–91
limited information regarding drivers of inpatient rehabilitation 5–9 44.1 28.3 13.0
resource use by stroke patients in an Asian context.18,21,33 10–24 42.6 28.4 15.7
We found the extent of independence in motor functions at 25–35 42.1 26.1 11.8
admission to be the strongest predictor of rehabilitation LOS
lower than for those who did not (0.26 vs 0.32; P⫽.015). In the CONCLUSION
public health care sector in Singapore, even though health The objective of our study was to determine the relative
services are subsidized through general taxation, subsidized importance of variables that can be assessed at the time of
patients still pay between 20% and 80% of their inpatient ex- admission in predicting acute rehabilitation LOS. We found
penses. Although the national catastrophic insurance scheme, Me- patients’ socioeconomic status and family structure to influence
dishield, pays for part of the bill, up to 60% of a large hospital bill LOS, and they should be considered in allocating resources and
is still being paid for by patients.38 Hence, patients who were determining treatment need. The results further suggest the
unable to continue to make functional gains could be discharged FIM motor score at admission to be a strong predictor of the
earlier to minimize their financial burden. In addition, with duration of stay, although cognitive function was not found to
increasing tension between the demand for health services and be an independent predictor. Hence, the use of FIM tools could
the cost of providing them, clinicians may be implicitly be extended to other acute rehabilitation hospital units to fa-
rationing health care resources by allocating resources ac- cilitate better management of bed resources.
cording to the rate at which rehabilitation gains can be
reached. Nonetheless, the availability of the family to pro- Acknowledgments: We thank Wai Fung Chong, BN, MBA, for
vide postdischarge care and the employment of foreign her assistance during the data-collection phase of the study and the
staff of Tan Tock Seng Rehabilitation Center for their help and support
domestic helpers as untrained caregivers39 facilitated the in this study.
discharge of medically complex patients.
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