Subject : Pharmacology
BASIC PRINCIPLES
Introduction
1. Introduction - Basic & Clinical Pharmacology - Answer (click here)
2. The History of Pharmacologyogy - Answer (click here)
3. Pharmacology & Genetics - Answer (click here)
4. Pharmacology and the Pharmaceutical Industry - Answer (click here)
5. The Nature of Drugs - Answer (click here)
6. Drug-Body Interactions - Answer (click here)
7. Pharmacodynamic Principles - Answer (click here)
8. Pharmacokinetic Principles - Answer (click here)
9. Drug Groups - Answer (click here)
Drug Biotransformation
1. Drug Biotransformation - Answer (click here)
2. Why is Drug Biotransformation Necessary? - Answer (click here)
3. The Role of Biotransformation In Drug Disposition - Answer (click here)
4. Where Do Drug Biotransformations Occur? - Answer (click here)
5. Microsomal Mixed Function Oxidase System & Phase I Reactions -
Answer (click here)
6. Human Liver P450 Enzymes - Answer (click here)
7. Phase II Reactions - Answer (click here)
8. Metabolism of Drugs to Toxic Products - Answer (click here)
9. Clinical Relevance of Drug Metabolism - Answer (click here)
Antihypertensive Agents
1. Antihypertensive Agents - Answer (click here)
2. Hypertension & Regulation of Blood Pressure - Answer (click here)
3. Basic Pharmacology of Antihypertensive Agents - Answer (click here)
4. Drugs that Alter Sodium & Water Balance - Answer (click here)
5. Drugs That Alter Sympathetic Nervous System Function - Answer (click
here)
6. Centrally Acting Sympathoplegic Drugs - Answer (click here)
7. Methyldopa - Answer (click here)
8. Clonidine - Answer (click here)
9. Ganglion-Blocking Agents - Answer (click here)
10. Adrenergic Neuron-Blocking Agents - Answer (click here)
11. Beta-Adrenoceptor-Blocking Agents - Answer (click here)
12. Prazosin & Other Alpha1 Blockers - Answer (click here)
13. Vasodilators - Answer (click here)
14. Hydralazine - Answer (click here)
15. Minoxidil - Answer (click here)
16. Sodium Nitroprusside - Answer (click here)
17. Diazoxide - Answer (click here)
18. Fenoldopam - Answer (click here)
19. Calcium Channel Blockers - Answer (click here)
20. Inhibitors of Angiotensin - Answer (click here)
21. Angiotensin-Converting Enzyme (ACE) Inhibitors - Answer (click here)
22. Angiotensin Receptor-Blocking Agents - Answer (click here)
23. Clinical Pharmacology of Antihypertensive Agents - Answer (click here)
24. Outpatient Therapy of Hypertension - Answer (click here)
25. Management of Hypertensive Emergencies - Answer (click here)
Diuretic Agents
1. Diuretic Agents - Answer (click here)
2. Proximal Tubule - Renal Tubule Transport Mechanisms - Answer (click
here)
3. Loop of Henle - Renal Tubule Transport Mechanisms - Answer (click here)
4. Distal Convoluted Tubule - Renal Tubule Transport Mechanisms -
Answer (click here)
5. Collecting Tubule System - Renal Tubule Transport Mechanisms -
Answer (click here)
6. Renal Autacoids - Renal Tubule Transport Mechanisms - Answer (click
here)
7. Adenosine - Answer (click here)
8. Prostaglandins - Answer (click here)
9. Peptides - Answer (click here)
10. Carbonic Anhydrase Inhibitors - Answer (click here)
11. Adenosine A1-Receptor Antagonists - Answer (click here)
12. Loop Diuretics - Answer (click here)
13. Thiazides - Answer (click here)
14. Potassium-Sparing Diuretics - Answer (click here)
15. Agents That Alter Water Excretion (Aquaretics) - Answer (click here)
16. Diuretic Combinations - Answer (click here)
17. Edematous States - Answer (click here)
18. Nonedematous States - Answer (click here)
Vasoactive Peptides
1. Vasoactive Peptides - Answer (click here)
2. Biosynthesis of Angiotensin - Answer (click here)
3. Actions of Angiotensin II - Answer (click here)
4. Angiotensin Receptors & Mechanism of Action - Answer (click here)
5. Biosynthesis of Kinins - Answer (click here)
6. Inhibition of the Renin-Angiotensin System - Answer (click here)
7. Formation of Kinins in Plasma & Tissues - Answer (click here)
8. Physiologic & Pathologic Effects of Kinins - Answer (click here)
9. Kinin Receptors & Mechanisms of Action - Answer (click here)
10. Metabolism of Kinins - Answer (click here)
11. Drugs Affecting the Kallikrein-Kinin System - Answer (click here)
12. Vasopressin - Answer (click here)
13. Vasopressin Receptors & Antagonists - Answer (click here)
14. Natriuretic Peptides - Answer (click here)
15. Vasopeptidase Inhibitors - Answer (click here)
16. Endothelins - Answer (click here)
17. Inhibitors of Endothelin Synthesis & Action - Answer (click here)
18. Vasoactive Intestinal Peptide - Answer (click here)
19. Substance P - Answer (click here)
20. Neurotensin - Answer (click here)
21. Calcitonin Gene Related Peptide - Answer (click here)
22. Adrenomedullin - Answer (click here)
23. Neuropeptide Y - Answer (click here)
24. Urotensin - Answer (click here)
Nitric Oxide
1. Discovery of Endogenously Generated Nitric Oxide - Answer (click here)
2. Nitric Oxide Synthesis, Signaling Mechanisms, & Inactivation - Answer
(click here)
3. Pharmacologic Manipulation of Nitric Oxide - Answer (click here)
4. Vascular Effects - Nitric Oxide in Disease - Answer (click here)
5. Septic Shock - Nitric Oxide in Disease - Answer (click here)
6. Infection & Inflammation - Nitric Oxide in Disease - Answer (click here)
7. The Central Nervous System - Nitric Oxide in Disease - Answer (click here)
8. The Peripheral Nervous System - Nitric Oxide in Disease - Answer (click
here)
9. Respiratory Disorders - Nitric Oxide in Disease - Answer (click here)
The Alcohols
1. The Alcohols - Answer (click here)
2. Basic Pharmacology of Ethanol: Pharmacokinetics - Answer (click here)
3. Pharmacodynamics of Acute Ethanol Consumption - Answer (click here)
4. Consequences of Chronic Alcohol Consumption - Answer (click here)
5. What Can Drunken Worms, Flies, and Mice Tell Us about Alcohol? -
Answer (click here)
6. Alcohol-Drug Interactions - Answer (click here)
7. Clinical Pharmacology of Ethanol - Answer (click here)
8. Management of Acute Alcohol Intoxication - Answer (click here)
9. Management of Alcohol Withdrawal Syndrome - Answer (click here)
10. Treatment of Alcoholism - Answer (click here)
11. Pharmacology of Methanol - Answer (click here)
12. Pharmacology of Ethylene Glycol - Answer (click here)
Antiseizure Drugs
1. Antiseizure Drugs - Answer (click here)
2. Drug Development for Epilepsy - Antiseizure Drugs - Answer (click here)
3. Basic Pharmacology of Antiseizure Drugs - Answer (click here)
4. Drugs Used in Partial Seizures Generalized Tonic-Clonic Seizures -
Answer (click here)
5. Phenytoin - Answer (click here)
6. Mephenytoin, Ethotoin, & Phenacemide - Answer (click here)
7. Carbamazepine - Answer (click here)
8. Oxcarbazepine - Answer (click here)
9. Eslicarbazine - Answer (click here)
10. Phenobarbital - Answer (click here)
11. Primidone - Answer (click here)
12. Felbamate - Answer (click here)
13. Gabapentin & Pregabalin - Answer (click here)
14. Lacosamide - Answer (click here)
15. Lamotrigine - Answer (click here)
16. Levetiracetam - Answer (click here)
17. Retigabine (Ezogabine) - Answer (click here)
18. Rufinamide - Answer (click here)
19. Stiripentol - Answer (click here)
20. Tiagabine - Answer (click here)
21. Topiramate - Answer (click here)
22. Vigabatrin - Answer (click here)
23. Zonisamide - Answer (click here)
24. Ethosuximide - Answer (click here)
25. Phensuximide & Methsuximide - Answer (click here)
26. Valproic Acid & Sodium Valproate - Answer (click here)
27. Oxazolidinediones - Answer (click here)
28. Benzodiazepines - Answer (click here)
29. Acetazolamide - Answer (click here)
30. Seizure Classification - Clinical Pharmacology of Antiseizure Drugs -
Answer (click here)
31. Therapeutic Strategy - Clinical Pharmacology of Antiseizure Drugs -
Answer (click here)
32. Management of Epilepsy - Answer (click here)
33. Special Aspects of the Toxicology of Antiseizure Drugs - Answer (click
here)
General Anesthetics
1. General Anesthetics - Answer (click here)
2. Mechanism of General Anesthetic Action - Answer (click here)
3. Inhaled Anesthetics - Answer (click here)
4. Pharmacokinetics - Inhaled Anesthetics - Answer (click here)
5. Pharmacodynamics - Inhaled Anesthetics - Answer (click here)
6. What Does Anesthesia Represent & Where Does It Work? - Answer (click
here)
7. Intravenous Anesthetics - Answer (click here)
8. Propofol - Intravenous Anesthetics - Answer (click here)
9. Fospropofol - Intravenous Anesthetics - Answer (click here)
10. Barbiturates - Intravenous Anesthetics - Answer (click here)
11. Benzodiazepines - Intravenous Anesthetics - Answer (click here)
12. Etomidate - Intravenous Anesthetics - Answer (click here)
13. Ketamine - Intravenous Anesthetics - Answer (click here)
14. Dexmedetomidine - Intravenous Anesthetics - Answer (click here)
15. Opioid Analgesics - Intravenous Anesthetics - Answer (click here)
16. Current Clinical Practice - Intravenous Anesthetics - Answer (click here)
Local Anesthetics
1. Local Anesthetics - Answer (click here)
2. Basic Pharmacology of Local Anesthetics - Answer (click here)
3. Historical Development of Local Anesthesia - Answer (click here)
4. Clinical Pharmacology of Local Anesthetics - Answer (click here)
5. Lipid Resuscitation - Answer (click here)
6. Commonly Used Local Anesthetics & Their Applications - Answer (click
here)
Antidepressant Agents
1. Antidepressant Agents - Answer (click here)
2. Pathophysiology of Major Depression - Answer (click here)
3. Neurotrophic Hypothesis - Answer (click here)
4. Monoamines and Other Neurotransmitters - Answer (click here)
5. Neuroendocrine Factors in the Pathophysiology of Depression - Answer
(click here)
6. Integration of Hypotheses Regarding the Pathophysiology of Depression
- Answer (click here)
7. Basic Pharmacology of Antidepressants - Answer (click here)
8. Clinical Indications - Clinical Pharmacology of Antidepressants - Answer
(click here)
9. Choosing an Antidepressant - Clinical Pharmacology of Antidepressants
- Answer (click here)
10. Dosing - Clinical Pharmacology of Antidepressants - Answer (click here)
11. Adverse Effects - Clinical Pharmacology of Antidepressants - Answer
(click here)
12. Overdose - Clinical Pharmacology of Antidepressants - Answer (click here)
13. Drug Interactions - Clinical Pharmacology of Antidepressants - Answer
(click here)
Drugs of Abuse
1. Drugs of Abuse - Answer (click here)
2. Dependence Versus Addiction - Answer (click here)
3. Addictive Drugs Increase the Level of Dopamine: Reinforcement -
Answer (click here)
4. Animal Models in Addiction Research - Answer (click here)
5. The Dopamine Hypothesis of Addiction - Answer (click here)
6. Dependence: Tolerance & Withdrawal - Drugs of Abuse - Answer (click
here)
7. Addiction: A Disease of Maladaptive Learning - Answer (click here)
8. Nonaddictive Drugs of Abuse - Answer (click here)
9. Basic Pharmacology of Drugs of Abuse - Answer (click here)
10. Opioids - Drugs That Activate Gio-Coupled Receptors - Answer (click here)
11. Cannabinoids - Drugs That Activate Gio-Coupled Receptors - Answer
(click here)
12. Gamma-Hydroxybutyric Acid - Drugs That Activate Gio-Coupled
Receptors - Answer (click here)
13. LSD, Mescaline, & Psilocybin - Answer (click here)
14. Drugs that Mediate their Effects via Ionotropic Receptors - Answer (click
here)
15. Drugs that Bind to Transporters of Biogenic Amines - Answer (click here)
16. Clinical Pharmacology of Dependence & Addiction - Answer (click here)
ENDOCRINE DRUGS
Hypothalamic Pituitary Hormones
1. Hypothalamic & Pituitary Hormones - Answer (click here)
2. Anterior Pituitary & Hypothalamic Hormone Receptors - Answer (click
here)
3. Growth Hormone (Somatotropin) - Answer (click here)
4. Treatment of Obesity - Answer (click here)
5. Mecasermin - Answer (click here)
6. Growth Hormone Antagonists - Answer (click here)
7. Gonadotropins & Human Chorionic Gonadotropin - Answer (click here)
8. Gonadotropin-Releasing Hormone & Its Analogs - Answer (click here)
9. GNRH Receptor Antagonists - Answer (click here)
10. Prolactin - Answer (click here)
11. Dopamine Agonists - Answer (click here)
12. Oxytocin - Answer (click here)
13. Oxytocin Antagonist - Answer (click here)
14. Vasopressin (Antidiuretic Hormone, ADH) - Answer (click here)
15. Vasopressin Antagonists - Answer (click here)
CHEMOTHERAPEUTIC DRUGS
Beta Lactam OtherCell Wall Membrane Active Antibiotics
1. Beta Lactam Compounds: Penicillins - Answer (click here)
2. Cephalosporins & Cephamycins - Answer (click here)
3. Monobactams - Beta Lactam Drugs - Answer (click here)
4. Beta-Lactamase Inhibitors (Clavulanic Acid, Sulbactam, & Tazobactam)
- Beta Lactam Drugs - Answer (click here)
5. Carbapenems - Beta Lactam Drugs - Answer (click here)
6. Glycopeptide Antibiotics - Answer (click here)
7. Other Cell Wall or Membrane Active Agents - Answer (click here)
Aminoglycosides Spectinomycin
1. General Properties of Aminoglycosides - Answer (click here)
2. Streptomycin - Answer (click here)
3. Gentamicin - Answer (click here)
4. Tobramycin - Answer (click here)
5. Amikacin - Answer (click here)
6. Netilmicin - Answer (click here)
7. Neomycin & Kanamycin - Answer (click here)
8. Spectinomycin - Answer (click here)
SulfonamidesTrimethoprim Quinolones
1. Sulfonamides - Antifolate Drugs - Answer (click here)
2. Trimethoprim & Trimethoprim-Sulfamethoxazole Mixtures - Antifolate
Drugs - Answer (click here)
3. Dna Gyrase Inhibitors : Fluoroquinolones - Answer (click here)
Antimycobacterial Drugs
1. Antimycobacterial Drugs - Answer (click here)
2. Drugs Used In Tuberculosis - Answer (click here)
3. Isoniazid - Drugs Used In Tuberculosis - Answer (click here)
4. Rifampin - Drugs Used In Tuberculosis - Answer (click here)
5. Ethambutol - Drugs Used In Tuberculosis - Answer (click here)
6. Pyrazinamide - Drugs Used In Tuberculosis - Answer (click here)
7. Streptomycin - Drugs Used In Tuberculosis - Answer (click here)
8. Second-Line Drugs for Tuberculosis - Answer (click here)
9. Rifaximin - Answer (click here)
10. Drugs Active Against Atypical Mycobacteria - Answer (click here)
11. Drugs Used in Leprosy - Answer (click here)
Antifungal Agents
1. Antifungal Agents - Answer (click here)
2. Amphotericin B - Answer (click here)
3. Flucytosine - Answer (click here)
4. Azoles - Answer (click here)
5. Echinocandins - Answer (click here)
6. Oral Systemic Antifungal Drugs for Mucocutaneous Infections - Answer
(click here)
7. Topical Antifungal Therapy - Answer (click here)
Antiviral Agents
1. Antiviral Agents - Answer (click here)
2. Agents to Treat Herpes Simplex Virus HSV & Varicella Zoster Virus
VZV Infections - Answer (click here)
3. Agents to Treat Cytomegalovirus CMV Infections - Answer (click here)
4. Antiretroviral Agents - Answer (click here)
5. Nucleoside & Nucleotide Reverse Transcriptase Inhibitors - Answer (click
here)
6. Nonnucleoside Reverse Transcriptase Inhibitors - Answer (click here)
7. Protease Inhibitors - Answer (click here)
8. Entry Inhibitors - Answer (click here)
9. Integrase Strand Transfer Inhibitors - Answer (click here)
10. New & Investigational Antiretroviral Agents - Answer (click here)
11. Treatment of Hepatitis B Virus Infection - Answer (click here)
12. Treatment of Hepatitis C Infection - Answer (click here)
13. Anti Influenza Agents - Answer (click here)
14. Other Antiviral Agents - Answer (click here)
Antiprotozoal Drugs
1. Parasite Life Cycle - Malaria - Answer (click here)
2. Drug Classification - Malaria - Answer (click here)
3. Chemoprophylaxis & Treatment - Malaria - Answer (click here)
4. Malaria: Chloroquine - Answer (click here)
5. Other Quinolines - Malaria - Answer (click here)
6. Artemisinin & Its Derivatives - Malaria - Answer (click here)
7. Quinine & Quinidine - Malaria - Answer (click here)
8. Mefloquine - Malaria - Answer (click here)
9. Primaquine - Malaria - Answer (click here)
10. Atovaquone - Malaria - Answer (click here)
11. Inhibitors of Folate Synthesis - Malaria - Answer (click here)
12. Antibiotics - Malaria - Answer (click here)
13. Halofantrine & Lumefantrine - Malaria - Answer (click here)
14. Treatment of Specific Forms of Amebiasis - Answer (click here)
15. Metronidazole & Tinidazole - Answer (click here)
16. Iodoquinol - Answer (click here)
17. Diloxanide Furoate - Answer (click here)
18. Paromomycin Sulfate - Answer (click here)
19. Emetine & Dehydroemetine - Answer (click here)
20. Pentamidine Antiprotozoal Drugs - Answer (click here)
21. Sodium Stibogluconate Antiprotozoal Drugs - Answer (click here)
22. Nitazoxanide Antiprotozoal Drugs - Answer (click here)
23. Other Drugs for Trypanosomiasis & Leishmaniasis - Answer (click here)
Cancer Chemotherapy
1. Cancer Chemotherapy - Answer (click here)
2. Causes of Cancer - Answer (click here)
3. Cancer Treatment Modalities - Answer (click here)
4. Role of Cell Cycle Kinetics & Anticancer Effect - Answer (click here)
5. Drug Resistance - Cancer Chemotherapy - Answer (click here)
6. Alkylating Agents - Pharmacology of Cancer Chemotherapeutic Drugs -
Answer (click here)
7. Nitrosoureas - Answer (click here)
8. Nonclassic Alkylating Agents - Answer (click here)
9. Platinum Analogs - Answer (click here)
10. Antimetabolites - Answer (click here)
11. Antifolates - Answer (click here)
12. Fluoropyrimidines - Answer (click here)
13. Deoxycytidine Analogs - Answer (click here)
14. Purine Antagonists - Answer (click here)
15. Vinca Alkaloids - Answer (click here)
16. Taxanes & Related Drugs - Answer (click here)
17. Epipodophyllotoxins - Answer (click here)
18. Camptothecins - Answer (click here)
19. Antitumor Antibiotics - Answer (click here)
20. Miscellaneous Anticancer Drugs - Answer (click here)
21. Clinical Pharmacology of Cancer Chemotherapeutic Drugs - Answer (click
here)
22. The Leukemias - Answer (click here)
23. Hodgkin’s Lymphoma - Answer (click here)
24. Non-Hodgkin’s Lymphoma - Answer (click here)
25. Multiple Myeloma - Answer (click here)
26. Breast Cancer - Answer (click here)
27. Gastrointestinal Cancers - Answer (click here)
28. Lung Cancer - Answer (click here)
29. Ovarian Cancer - Answer (click here)
30. Testicular Cancer - Answer (click here)
31. Malignant Melanoma - Answer (click here)
32. Brain Cancer - Answer (click here)
33. Secondary Malignancies & Cancer Chemotherapy - Answer (click here)
Immunopharmacology
1. Immunopharmacology - Answer (click here)
2. Normal Immune Responses - Answer (click here)
3. Abnormal Immune Responses - Answer (click here)
4. Glucocorticoids - Immunosuppressive Agents - Answer (click here)
5. Calcineurin Inhibitors - Immunosuppressive Agents - Answer (click here)
6. Mammalian Target Of Rapamycin (mTOR) Inhibitors - Answer (click here)
7. Mycophenolate Mofetil - Immunosuppressive Agents - Answer (click here)
8. Immunomodulatory Derivatives Of Thalidomide (IMiDs) - Answer (click
here)
9. Cytotoxic Agents - Immunosuppressive Agents - Answer (click here)
10. Immunosuppressive Antibodies - Answer (click here)
11. Monoclonal Antibodies (MABs) - Answer (click here)
12. Clinical Uses of Immunosuppressive Drugs - Answer (click here)
13. Immunologic Reactions to Drugs & Drug Allergy - Answer (click here)
14. Immediate (Type I) Drug Allergy - Answer (click here)
15. Autoimmune (Type Ii) Reactions to Drugs - Answer (click here)
16. Serum Sickness & Vasculitic (Type III) Reactions - Answer (click here)
TOXICOLOGY
Introduction to Toxicology Occupational Environmental
1. Introduction to Toxicology: Occupational & Environmental - Answer
(click here)
2. Toxicologic Terms & Definitions - Answer (click here)
3. Environmental Considerations - Toxicology - Answer (click here)
4. Air Pollutants - Specific Chemicals - Answer (click here)
5. Solvents - Specific Chemicals - Answer (click here)
6. Pesticides - Specific Chemicals - Answer (click here)
7. Herbicides - Specific Chemicals - Answer (click here)
8. Environmental Pollutants - Specific Chemicals - Answer (click here)
9. Metals - Specific Chemicals - Answer (click here)
SPECIAL TOPICS
Special Aspects of Perinatal Pediatric Pharmacology
1. Drug Therapy in Pregnancy - Answer (click here)
2. Drug Therapy in Infants & Children - Answer (click here)
3. Pediatric Dosage Forms & Compliance - Answer (click here)
4. Drug Use During Lactation - Answer (click here)
5. Pediatric Drug Dosage - Answer (click here)
Dermatologic Pharmacology
1. Dermatologic Pharmacology - Answer (click here)
2. Dermatologic Vehicles - Answer (click here)
3. Antibacterial Agents - Answer (click here)
4. Antifungal Agents - Answer (click here)
5. Oral Antifungal Agents - Answer (click here)
6. Topical Antiviral Agents - Answer (click here)
7. Immunomodulators - Answer (click here)
8. Ectoparasiticides - Answer (click here)
9. Agents Affecting Pigmentation - Answer (click here)
10. Sunscreens - Answer (click here)
11. Acne Preparations - Answer (click here)
12. Drugs for Psoriasis - Answer (click here)
13. Biologic Agents - Answer (click here)
14. Anti Inflammatory Agents - Answer (click here)
15. Keratolytic & Destructive Agents - Answer (click here)
16. Antipruritic Agents - Answer (click here)
17. Trichogenic & Antitrichogenic Agents - Answer (click here)
18. Antineoplastic Agents - Answer (click here)
19. Antiseborrhea Agents - Answer (click here)