Acute
Rheumatic Fever in the Era of Doppler
Echocardiography
A Scientific Statement From the American Heart
Association
Circulation
Volume 131(20):1806-1818
May 19, 2015
Introduction
• Although acute rheumatic fever (ARF) has
declined in Europe and North America in
incidence, the disease remains one of the most
important causes of cardiovascular morbidity
and mortality in the developing countries
• The Jones criteria, used for guidance in the
diagnosis of ARF since 1944, were last modified
by the American Heart Association (AHA) in
1992.
• In the past few years, developments in several
areas have prompted reexamination of the
traditional Jones criteria.
• As echocardiographic techniques and
applications, including quantitative Doppler and
color flow mapping, have evolved worldwide
during the past 2 decades, Other national and
regional guidelines for the diagnosis of ARF
have recently included the use of
echocardiography/ Doppler methodologies.
• Numerous studies from a broad range of clinical
circumstances have suggested that there be
more widespread use of echocardiography as a
way to diagnose carditis even in the absence of
overt clinical findings (“subclinical carditis”).
Incidence of ARF: Declined over past 4 to 6 decades.
Low risk:
ARF incidence <2 per 100,000 school-aged children (5-14
years old) per year, or
an all-age prevalence of RHD of ≤1 per 1,000
population per year (Class IIa, Level of Evidence C).
Arthritis (35%–66%)