Coagulation

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1. activated proenzymes (usually factor XII): platelet factor (PF-3)

2. Ca2: clotting factor (VII)
3. Ca2+: clotting factors (VIII,IX)
4. clotting factors (VIII, IX): factor X activator complex
5. clotting factor (VII): tissue factor complex
6. coagulation phase diagram:

7. common pathway: Factor X, Prothrombinase, prothrombin, thrombin, fibrin, fibrinogen.

8. extrinsic pathway: tissue damage, tissue factor (factor III), Ca2, clotting factor (VII), tissue factor complex.
9. Factor X: prothrombinase
10. fibrinogen: fibrin
11. intrinsic pathway: activated proenzymes (usually factor XII) platelet factor (PF-3), Ca2, clotting factors (VIII, IX), factor X activator
complex.
12. platelet factor (PF-3): Ca2
13. prothrombin: thrombin
14. prothrombinase: prothrombin
15. thrombin: fibrinogen
16. Tissue damage: tissue factor (factor III)
17. tissue factor (factor III): Ca2