Brett Lyons
Environment and Animal Health Group
Environmental Risk Assessment
• Multi-disciplinary approach to the risk
assessment of organic and inorganic
chemicals in aquatic ecosystems.
• Fate and effects of natural and
synthetic chemicals in both fresh
water and marine systems (including
food chain assessments).
• Scientists actively involved in OECD
and other international test guideline
developments.
– Chair UK NC3Rs (Replacement, Refinement
and Reduction) Regulatory Toxicology
Committee (Ecotoxicology Working Group).
– OECD Endocrine Disrupters Testing &
Assessment Working Group (Ecotoxicology
Validation Management Group).
– OECD Validation Management Group in
Ecotoxicology for test guideline
development (Fish Experts Group).
Environmental Chemistry and Fate
• Extensive analytical chemistry
capabilities for metals, nutrients,
organic chemicals and radionuclides,
including trace level environmental
analyses.
Biological
analysis
Chemical
analysis
Biological
Fractionation analysis
Responsible
toxicant
Bespoke testing systems
The stickleback as a sentinel and model species
Toxico-genomic platforms
Testicular pathology:
Intersex (ovotestis) Field monitoring
Chemical risk and population relevant endpoints
Sebire et al., (2008). The model anti-androgen flutamide suppresses the expression of typical male
stickleback reproductive behaviour. Aquatic Toxicology 90 (1), pp. 37-47.
For further information please
contact:
brett.lyons@cefas.co.uk
jason.weeks@cefas.co.uk
tom.hutchinson@cefas.co.uk