Methods
Results
When compared to the controls, the condyles of the rats subjected to hg-per-
propulsion showed the following characteristics :
1. The articular disc was significantly thiclrcr.
2. The articular zone was distinctly higher and the cells were rounder.
3. The prechondrololastic zone (the so-eilllcd inkmediate zone) was
significantly elongated (Figs. 1 and 2). This certainly results from an
increased cell proliferation, as evidcncctl by a statistically significant rise
in the number of cell divisions as reported in a previous article.” Individ-
ually, cells generally ha\-e a slightly larger and clearer nucleus. (Mean
surface increase is about 12 per cent.)
Fig. 1
Fig. 2
Figs. 1 and 2. Condyles of control and treated rats. These rats came from the same litter,
one (Fig. 1) as a control and the other [Fig. 2) being put for a J-week period under man-
dibular hyperpropulsion. The above figures show sagittal sections through the condyles. A
comparison of the two figures shows that the prechondroblastic zone in the treated rat is
significantly increased in length.
4. The chondroblastic zone becomes also elongated, but the comparison
of results obtained after 1 to 4 weeks seems to favor the interpretation
that one is dealing here with a phenomenon secondary to the increased
act,ivity of the prechondroblastic zone.
5. The angle drawn through the condyle to the inferior border of the
mandible in the treated animal is 3 degrees larger. At the same time, as
evidenced by tetracycline labeling, the periosteal bone apposition on
the posterior border and the rear of the inferior border of the mandible
was increased.
Discussion
Conclusion