DAFTAR ISI

LEMBAR PENGESAHAN ................................................................................... i

LEMBAR PERNYATAAN .................................................................................. ii

ABSTRAK ............................................................................................................ iii

ABSTRACT ............................................................................................................v

DAFTAR RIWAYAT HIDUP ........................................................................... vii

KATA PENGANTAR ........................................................................................ viii

DAFTAR ISI ...........................................................................................................x

DAFTAR TABEL .............................................................................................. xiv

DAFTAR GAMBAR .......................................................................................... xvi

DAFTAR SINGKATAN ................................................................................... xvii

BAB 1 PENDAHULUAN ......................................................................................1

1.1 Latar Belakang .......................................................................................1

1.2 Perumusan Masalah ...............................................................................3

1.3 Tujuan Penelitian ...................................................................................3

1.3.1 Tujuan Umum .........................................................................3

1.3.2 Tujuan Khusus ........................................................................4

1.4 Manfaat Penelitian .................................................................................4

1.4.1 Bagi Peneliti ............................................................................4

1.4.2 Bagi Institusi ...........................................................................4

1.4.3 Bagi Masyarakat......................................................................4

1.4.4 Bagi Peneliti Lain ....................................................................4

BAB 2 TINJAUAN PUSTAKA .............................................................................5

2.1 Defenisi Malaria .....................................................................................5

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 2.2 Faktor Resiko dan Etiologi Malaria .......................................................5

2.2.1 Host .........................................................................................5

2.2.2 Agent Penyakit Malaria ..........................................................7

2.2.3 Faktor Lingkungan (Enviroment) .........................................11

2.3 Daur Hidup Plasmodium ......................................................................13

2.4 Cara Penularan .....................................................................................13

2.5 Patogenesis Malaria .............................................................................14

2.6 Gejala Malaria ......................................................................................15

2.6.1 Demam ..................................................................................15

2.6.2 Splenomegali .........................................................................16

2.6.3 Anemia ..................................................................................16

2.7 Diagnosis Malaria ................................................................................17

2.7.1 Anamnesis .............................................................................17

2.7.2 Pemeriksaan Fisik .................................................................17

2.7.3 Pemeriksaan Penunjang ........................................................18

2.8 Komplikasi ...........................................................................................20

2.9 Penatalaksanaan ...................................................................................22

2.9.1 Pengobatan Malaria Tanpa Komplikasi ................................22

2.9.2 Pengobatan Malaria Dengan Komplikasi..............................27

2.9.3 Penanganan Anemia Berat ....................................................29

2.10 Pencegahan .........................................................................................29

2.10.1 Tindakan Pencegahan Umum .............................................29

2.10.2 Profilaksis Malaria ..............................................................29

BAB 3 KERANGKA KONSEP DAN DEFENISI OPERASIONAL ...............30

3.1 Kerangka Konsep .................................................................................30

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 3.2 Defenisi Operasional ............................................................................31

BAB 4 METODE PENELITIAN ........................................................................35

4.1 Jenis dan Desain Penelitian ..................................................................35

4.2 Lokasi dan Waktu Penelitian ...............................................................35

4.2.1 Lokasi Penelitian ...................................................................35

4.2.2 Waktu Penelitian ...................................................................35

4.3 Populasi dan Sampel ............................................................................35

4.3.1 Populasi .................................................................................35

4.3.2 Sampel ...................................................................................35

4.4 Metode Pengumpulan Data ..................................................................35

4.5 Metode Analisa Data ............................................................................36

BAB 5 HASIL PENELITIAN DAN PEMBAHASAN ......................................37

5.1 Gambaran Umum RSUD Gunungsitoli Nias .......................................37

5.2 Hasil Penelitian ....................................................................................39

5.2.1 Distribusi pada pasien malaria dewasa yang dirawat inap

berdasarkan sosiodemografi (umur, jenis kelamin dan
pekerjaan) ...........................................................................39

5.2.2 Distribusi pada pasien malaria dewasa yang dirawat inap

berdasarkan gejala klinis (keluhan utama dan keluhan
tambahan) ...........................................................................41

5.2.3 Distribusi pada pasien malaria dewasa yang dirawat inap

berdasarkan pemeriksaan fisik (inspeksi dan palpasi) ........42

5.2.4 Distribusi pada pasien malaria dewasa yang dirawat inap

berdasarkan pemeriksaan penunjang (pemeriksaan darah
tepi dan darah rutin) ............................................................43

5.2.5 Distribusi pada pasien malaria dewasa yang dirawat inap

berdasarkan penatalaksanaan ..............................................45

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 5.2.6 Distribusi pada pasien malaria dewasa yang dirawat inap
berdasarkan komplikasi ......................................................46

5.3 Pembahasan ..........................................................................................46

BAB 6 KESIMPULAN DAN SARAN ................................................................50

DAFTAR PUSTAKA ...........................................................................................52

LAMPIRAN ..............................................................................................................

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