Name of Drug Classification and Mechanism of Indication and Contraindication Side Effects or Adverse Nursing Responsibilities
(Dosage, Route, Frequency, Action Reactions
Timing)
Generic Name: Classification: Indication: white patches or sores 14 rights of medication
1. Right Drug/Medication Amoxicillin Penicillins This drug is a semi-synthetic inside your mouth or on 2. Right Client/Patient broad spectrum penicillin closely your lips; 3. Right Route related to Ampicillin. It binds to fever, swollen glands, rash 4. Right Dose Brand Name: Penicillin-binding proteins in the or itching, joint pain, or 5. Right Frequency/Time Amoxil Mechanism of Action: cytoplasmic membranes of 6. Right Assessment general ill feeling; 7. Right Approach Description: Amoxicillin inhibits the bacteria, thus inhibiting cell-wall pale or yellowed skin, 8. Right Education final transpeptidation step of synthesis. It also inhibits cell peptidoglycan synthesis in bacterial yellowing of the eyes, dark 9. Right Evaluation Dosage: cell wall by binding to 1 or more of the growth and cell division. It is colored urine, fever, 10. Right Documentation 500mg 1cap penicillin-binding proteins (PBPs), thus better absorbed than Ampicillin. confusion or weakness; 11. Right to Refuse 12. Right Principle of Care inhibiting cell wall biosynthesis severe tingling, numbness, 13. Right Prescription resulting in bacterial lysis. pain, muscle weakness; 14. Right Nurse Clinician Pharmacokinetics: Absorption: Rapidly and completely easy bruising, unusual Route: absorbed from the GI tract. Time to bleeding... Assessment & Drug Effects Oral peak plasma concentration: 1-2 hr. Determine previous hypersensitivity reactions Distribution: Widely distributed into to penicillins, cephalosporins, and other body tissues and fluids. Crosses the allergens prior to therapy. Contraindication: Lab tests: Baseline C&S tests prior to placenta and enters breast milk (small Hypersensitivity to amoxicillin amounts). Plasma protein binding: initiation of therapy, start drug pending Frequency: Approx 20%. and other penicillins. results; periodic assessments of renal, hepatic, TID Metabolism: Undergoes partial hepatic and hematologic functions should be made metabolism and converted to during prolonged therapy. penicilloic acid. Monitor for S&S of an urticarial rash (usually Excretion: Via urine (60% as occurring within a few days after start of unchanged drug) and faeces. Plasma drug) suggestive of a hypersensitivity Timing: half-life: 1-1.5 hr. reaction. If it occurs, look for other signs of 7, 1, 7 hypersensitivity (fever, wheezing, generalized itching, dyspnea), and report to physician immediately. Report onset of generalized, erythematous, maculopapular rash (ampicillin rash) to physician. Ampicillin rash is not due to hypersensitivity; however, hypersensitivity should be ruled out. Closely monitor diarrhea to rule out pseudomembranous colitis. Patient & Family Education
Take drug around the clock, do not miss a
dose, and continue therapy until all medication is taken, unless otherwise directed by physician. Report onset of diarrhea and other possible symptoms of superinfection to physician (see Appendix F).