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1- The major action of sodium chromoglycate is:
a-mast cell stabilization b-bronchodilator
c-prostaglandins modifier d-leukotrienes modifier e-non of the above
4- Inderal is :
a-similar in action to ergotamine
b-similar in action to tubocurarine
c-used as an antihistamine
d-pure b -adrenergic receptor blocker
10- Erythroped A :
a-Effective against G+ve Cocci b- A macrolide antibiotic c- Increase g.i.t. motility
d-could be used in pregnant women if need e- all of the above
1
11- For the treatment of anaphylactic shock use :
a-salbutamol b-diphenhydramine
c-acetazolamide d-epinephrine
e-aminophylline
2
19- Adenosine P produces which of the following :
a-facial flushing b-dyspnea
c-marked tachycardia d- a and b
e- a , b and c
25- Which of the following is released by bacterial infection?(…. by bacterial cell wall
during there growth):
a-endotoxin b-exotoxin c-antibiotics
d-cytotoxin e-non of the above
28- Patients prescribed non reversible monoamine oxidase inhibitor should be advised
not to consume food containing tyramine because this combination causes:
a-postural hypotension b-hallucinations
c-anaphylactic shock d-muscle weakness and tremor
e-acute adrenergic crisis including sever hypertention
3
c-cardiac toxicity is a recent concern of this class
d-they usually administrated twice daily
e-combination with non selective agents give more effective action
36- A patient who is admitted through the E.R. with an initial diagnosis arterial fibrillation :
a-slow ventricular response using verapamil b-start lidocaine infusion
c- considered anticoagulation with warfarine d- a and c
e- b and c
4
38- When diagnosis of diabetes to be considered :
a-WBC count with differential
b-oral glucose tolerance test c- HBA1c
d- a and b e- b and c
42- What first line agent may be considered for an obese type 2 ?
a-glyburinid b-insulin c-metformin
d-nateglinid e-repaglinid
44- Which of the following drugs exhibits dose dependant pharmaceutical therapeutic doses ?
a-Na valproate b-phenytoin c-lithium
d-quinidine e-carbamazepine
5
47- Which of the following is NOT correct ?
a-glitazones are ineffective as mono therapy
b-GIT disturbance are common side effects of glycosidase inhibitors-a
c-start with small dose of oral agent and triturate up to 1-2 weeks
d-life style modification should not be enforced if an oral agent to be started
e-lisepro is rapid acting insulin to be dosed immediately before meals
51- When a CNS depressant is prescribed , which of the following is NOT taken at the
same time?
a-analgesic b-verapamil
c-aspirin d-diphenhydramine e-orange juice
53- The drug of choice to control pain during acute myocardial infarction is :
a-naloxone b-bethidine c-morphine
d-celecoxib e-naproxen
6
b- fetal risk NOT demonstrated in animal studies but there are no controlled studies in pregnant
women or animal reproduction studies have shown an adverse effect that was NOT confirmed in
controlled studies in women during trimester
c- either animal study have revealed adverse effect on the fetus and there are no controlled
human studies or studies in animal and women are not available
d- There is positive evidence of human fetal risk but the benefits of use in pregnant woman may
be acceptable despite the risk
58- Which route of administration would provide the most rapid onset of action response
to morphine ?
a-oral b-S.C. c-I.V. d-I.M. e-rectal
7
63- Regarding treatment of digoxin toxicity:
a-verify time of last time
b-check Mg and K levels and correct if needed c-monitor ECG
d-no antidote for digoxin e-supportive care
68- When drug absorbed through GIT then go to liver and excreted this process called:
a- first pass b- drug metabolism c- drug distribution
8
76- to increase duration of lidocaine in anasethia :
a- propranolol b- succinyl choline c- epinephrine
d- Atropine e- .................
9
84-if packaged are written for expiry November 2006 it mean that can be
90- if patient take Gentamicin for a time which of the following need monitoring test:
a- serum creatinine level b- liver enz. test
10
93- antiarrythmic drug class Ιb produce its action through:-
a- decrease rate of phase 0 depolarization b- increase phase 3 repolarization
c- decrease phase 4 depolarization d- adrenergic receptor blocking
e- shorten phase 3 repolarization
98- ophthalmic prescription are written through following ( gtt tod Bid ) this mean:-
a- give one drop to right eye twice daily
b- give one drop to left eye twice daily
c- shake well and then give one drop to left eye twice daily
d- shake well and then give one drop to right eye twice daily.
11
101-all the following are antifungal except:-
a- Nystatin b- Amphotericin
c- Ketoconazole d- Ganciclovir.
12
111-in ovulation phase which hormone is predominant :-
a-FSH b-LH
112-vecuronium is used as :-
skeletal muscle relaxant.
b- Magnesium sulphate
c- Calcium sulphate
13
119-normal water can be used in:-
a- parentral prep. b-ophthalmic prep.
c- oral susp. d-external prep.
d- reversible e- B,C
14
128-pt CHF take digoxin and hydrochlorothiazide with ray arthritis which of :
a-cortizone b-hydrocortisone
c-fluticazone d-prednisolone
129-if a drug has the same active ingredient like other drug but not contain
130- conc. of adrug is 7.5 mg in teaspoonful what will be conc. in 150 ml:-
7.5 mg________ 5ml
x? mg________ 150 ml
x mg=7.5x150/5 =225 mg
133-Alteblase is used:-
fibrinolytic (thrombolytic)
15
137-Doxorubicin side effect :-
a- cardiac toxicity b- nephrotoxicity
16
146- Daily recommended dose for vit. C in female :- “ Check page’97 “
d- lipid e- protein
17
*156- In case of hepatic or renal failure which muscle relaxant is recommended:-
????????
159-Enixoparin is administrated:-
a- IM
b- IV
c- S.C.
d- d- IV infusion
18
*167- which of the following not characteristic of theophylline:-
a- relaxation to brochial smooth muscle
e- convulsion
d- sedation
d-esmolol e- quinidine
19
175- in phase 1 in muscle contraction occur:-
a- depolarization for k in b- repolarization to ca out
c) hyperglycemia d) hypoglycemia
e) b + d
b) hemolysis
c) hyperglycemia
d) hypoglycemia
e) b + d
c- lipid d-carbohydrate
20
183- major metabolism proccess in GIT is:-
a-hydrolysis b- acetylation
c- oxidation d-conjucation
21
193-most of drugs are :
a-Weak electrolyte
b-Non electrlolyte
c-Non ionic
d-Strong electrolyte
b-phenytoin administration
c-give lidocaine
e-electrical cardio
b-Bronchospasm
d-Chest pain
b-Primary product
22
b-Alopecia
b- +ve inotropic
c- Hypertension
d- Tachycardia
e- Bradycardia
b-Protein binding
b-Emollient
c- A&B
d-Increase absorption
e-Increase distribution
23
206- In hypodynamic shock treatment we used :-
a- dopamine
b- nicotine
b- aspirin
207-acyclovir used to :
Herbs simplex
b-Estazolam
c-Triazolam
d-Temazepam
b-Amphetamine
211-desmopressine used in :-
nocturnal enuresis &diabetes insipidus
24
*Pentofyllin is indicated in diseases, causing disorders in the peripheral
perfusion, and in diabetes, atherosclerotic and inflammatory disorders, including
shank ulcers; gangrene; diabetic angiopathy; intermittent claudication;
Raynaud’s disease. In acute disorders of the brain perfusion, including ischemic
stroke and resultant conditions. Acute disorders of the retinal blood supply.
b-Less toxicity
c-Narrow therapeutic
e-Usually IV , IM
b-vasoconstrictive
d-effective orally
e-S.C
b-1st order
c-2nd order
d-Mixed order
e-A + B
25
218- Which of the following is NOT predinsolone side effect ?
a-cataract b-hypoglycemia
b-Easy to handle
c-More stable
d-Faster action
e-B + C
b-Enteric coat
c-Grinding of tablet
26
224-drug used for peptic ulcer ?
Losec
225- drug infusion rate is 2mg\kg\hr , infused for 12 hours , for 70kg patient. what
is total dose?
(2x70x12)=1680 mg
228-when U know the preservative used with anti biotic is n’t suitable you make:-
a- use another one is suitable
c- use tow or more preservative may increase the activity and may become suitable
d- a+c
27
232-Cholystyramin resin act by :- anion exchange
237-Isoproterenol( Isoprenaline ):
adrenergic agonist medication.
e-clarithromycin
c-propranolol d-captopril
e- clonidine
28
243-comparison between sterile water &water for injection:-
a- pyrogen free b-free from sod. Chloride
e- A&C
c-propranolol d- hydralzyine
245- Which of the following drug has side effect lupus like syndrome :
a- lidocaine b-minoxdile
c- procainamide d-hydrochlorothiazide
c-cloramphinicol d-amikacine
e-Inhibitors of metabolism
c- Amoxicillin d- penicillin V
29
251-Auxliar of label are written on box contain CO-TRIMETHOXAZOLE all is true
except:-
a-shake the bottle before use
b-suspension
c-freezing of drug
b-in freezing
c-at 10-20 c*
d-A&C
e-A&B
[
b-vomiting .alopecia
d-A&B e-B&C
30
260-All (ACEIs) are prodrug except:- CAPTOPRIL (prototype)
271-The equation that determine the acid & base degree is:-
BRONESTED EQUATION
31
272-ISONIAZIDE used in: TuBERclosis .
c-Hypokalaemia d-Hyeruriceamia
e-Hyponatrimia
276-Vit. A daily dose is 30,000-50,000 IU for the correction of the deficiency &for
therapy from 100,000-200,000 IU/day.
c-Hypokalaemia d-Hyeruriceamia
e-Hyponatrimia
32
284- Calcipotriol is indicated for :- PSORIASIS
290-Prmethazine used as :-
Anti histaminic (pruritus , cough ,anti emetic)
292-ESMOLO is:-
Short acting B- blocker used in emergency in Acute arrhythmia as IV administration .
294-cyclizine used in :-
a-nausea &vomiting b-antibiotic
c-bronchodilator d-antihistaminic
c-constipation d-bronchospasm
e-urinary retention
33
296-propencid increase the con. Of penicillin through :-
a-increase renal tubular reabsorption
302-Isopretrenol is :-
a-alpha &beta agonist b-alpha blocker
e-beta blocker
(Anticholinesterases <irreversible> )
34
305- The latin abbreviation for<state>:- (Immediately )
e- Headach
c-senna d- a&b
c-1:5 d-1:10
35
317-Dipivefrine is:-
a-Anti HTN b-chelating agent
c-Glucoma
[[
36
327-The least sedating:-
a) Diazepam b) chlorodiazepoxide e) probamate
f) oxazepam g) buspirone
37
338-Na picosulfate is used for : laxative
344-Properties of catecholamine:-
a)rapid metabolism by ACHE. b)slow metabolism by ache
c)slow COMT d)rapid metabolism by COMT and MAO.
38
349- natural water can be used in :- external preparation
c-………………
C-hydralazin d-……………
c-……………………………………
39
359-pentoxifylline use as :-
a- peripheral vasoconstriction
b- dry cough
3-synthesis of cholesterol
4-decreas lipoprotein
b-distal water
365- pH use to :
a-determine acidity
b- increase with basic c-for POH
40
368- Which of the following drugs is a systemic amoebicide?
a-Diloxamide furoate
b-Pyrimethamine
c-Emetin
d-Sodium Stibogluconate
369-Which of following drugs is the drug of choice for the treatment of all forms
of Schistosomiasis?
a-Praziquantel
b-Mebendazole
c-Niclosamide
d-Thiabendazole
370-Which of the following drugs can be used for the treatment of influenza A
infection ?
a-Zidovudine(AZT)
b-Amantadine
c-Ribavarin
d-Vidarabine
41
c-Renal failure d-CNS suppression
376-Which of the following are side effects of phenytoin treatment?
a-Acne
b-Hirsuitism
c-Gingival hyperplasia
d-a,b,and c
42
384-All These drugs can be used for Parkinsonism except :
a- Selgitine HCL
b- Carbidopa
c- Pergolide
d- Nedocromil Sod.
43
392-Sumatriptan is used for :-
a- Hypertension
b- Treatment of migraine
c- Angina Pectoris
d- Control of Epilepsy
44
401-Dobutamine is given I.V. because :-
a- It is not stable in the gastric PH
b- It is needed in large quantities in case of oral route
c- It is eliminated very quickly
d- None of the above
403-Cefaclor is :
a- Ist, Generation Cephalosporin
b- 2nd, generation Cephalosporin
c- 3rd, generation Cephalosporin
d- None of the above
45
1- ACE mechanism is:
a- converting Ag 11 to vasoconstrictor Ag1
b- converting Ag 1 to vasoconstrictor Ag11
c- converting Ag 1 to vasodilator Ag11
d- converting Ag 11 to vasoconstrictor Ag1
46
10- All of the following are ß2 antagonists except:
a- Salbutamol.
b- Metoprolol.
c- Nadolol.
d- Atenolol.
N.B.: Salbutamol is ß2 agonoist
47
d- Anti arrhythmic agent.
48
C- Urikinase. D- Vitamin A.
28- Zinnat contains:
A-Cefuroxime. B- Cefaclor.
49
37- Triazole is:
a- Antifungal.
b- The trade name of clotrimazole.
c- The trade name of amphotrecin B.
d- Nyatatin.
50
47- misoprostol [cytotec = prostaglandin] inhibits gastric acid by blocking
hydrogen-potassium adenosine triphosphate enzyme system [ATP] of gastric cell:
a- True
b- False.
54- All these medications are used in the treatment of T.B. except:
a- INH.
b- Rifampicin.
c- Cycloserin.
d- Cyclosporine.
51
58- Amantadine is used for all of the following except:
a- Antiviral.
b- For influenza A.
c- Anti-parkinsonism.
d- For influenza B.
66- What is the most drug can cause damage if it is given OTC?
a- Warfarin.
b- Captopril.
c- Chlorothiazide.
d- Rifampicin.
52
67- All are OTC drugs except:
a- Biscodil
b- Aspirin.
c- Antacids.
d- Tegretol.
53
76- Binding to plasma protein:
a- Increases half life.
b- Decreases half life.
54
86- Immunocompetent means?
Control resistant to infections.
91- Which one of the following is used in Benign prostatic hyperplasia [BPHP]?
a- Finasteride, (proscar).
b- Flumazenil.
c- Cefprozil.
d- Mevacurim.
55
96- Ticlopidine is used as:
a- Antiplatelet.
b- Antibiotic.
c- Anticholinergic.
d- Anti-coagulant.
56
*105- Drug which increases the action of warfarin is:
a- Carbimazole.
b- Oral contraceptive.
c- Phenobarbitone.
d- None of the above.
108- Which one reduces the metabolism of other drugs in the liver?
a- Rifampicin.
b- Vitamin C.
c- Cimetidine.
d- Metrinidazole.
109- Which one induces the metabolism of other drugs in the liver?
a- Rifampicin.
b- Vitamin C.
c- Cimetdine.
d- Metronidazole.
57
113- Hepatotoxicity is induced due to these drugs except:
a- Rifampicin.
b- Ketoconazole.
c- Quinolones.
d- Dipyridamole.
58
122- All of these are corticosteroids except:
a- Methyl prednisolone.
b- Prednisolone.
c- Triamcinolone.
d- Beclomethasone.
e- Dexamethasone.
f- Ondansteron [5HT3 receptor antagonist, anti emetic].
59
131- The drug of choice for febrile convulsion in children is:
Diazepam 250 microgram / Kg.
60
140- One of the following not used in epilepsy:
a- Clonazepam.
b- Phenytoin.
c- Primidone.
d- Imipramine (tricyclic antidepressant).
146- Omeprazole:
a- Acts as proton pump inhibitor.
b- Blocks the hydrogen-potassium ATP enzyme system.
c- A & B.
61
148- Hepatitis vaccine does is:
a- Three times / year.
b- Twice / year.
c- Once / year.
155- Vitamin A daily dose for the correction of deficiency is: 30,000 – 50,000 IU.
Vitamin A daily dose for therapy is: 100,000 – 200,000 IU.
62
158- Source of human insulin is E-coli by:
a- Biosynthetically by recombinant DNA technology using E-coli.
b- Semi synthetically by enzymatic modification of protein material.
c- A & B are correct.
159- When you store drug at low temperature you must consider the following:
a- Storage of dusting powder below 00C causes the accumulation of granules.
b- Storage of cream & ointment below 50C causes cracking.
c- Storage of insulin below 00C causes aggregation of insulin.
d- All of above.
164- Estrogen:
a- Reduces the incidence of coronary diseases in postmenopausal women.
b- Can be taken for life time.
c- Are ineffective when taken orally.
63
167- Quinolones are contraindicated in children because:
a- Affect joints.
b- Affect liver.
c- Do not affect children.
171- Which one of these symptoms does not occur with morphine?
a- Respiratory depression.
b- Constipation.
c- Vomiting.
d- Diarrhea.
172- Which one of these drugs is not used for acute pain?
a- Naproxen.
b- Clochicine.
c- Ibuprofen.
d- Codeine.
e- Prednisolone.
173- Which one of these drugs is drugs of choice for Myxodema (hypothyroidism)?
a- Thyroxin sodium.
b- Carbimazole.
c- Iodine.
d- Propyl thiouracil.
64
176- The steady state concentration of the drug in the plasma depends on:
a- Direct proportion to the rate of elimination.
b- Indirect proportion to the rate of elimination.
c- Direct proportion to the rate of administration.
d- Indirect proportion to the rate of administration.
65
185- Cefaclor is:
a- 1st generation cepharosporins.
b- 2nd generation cepharosporins.
c- 3rd generation cepharosporins.
186- Teicoplanin antibiotic has similar effect on gram positive bacteria as:
a- Vancomycin.
b- Jamicain.
c- Gentamycin.
d- Kanamycine.
190- Tetracycline when taken with minerals such as calcium, iron and aluminium forms
a chelate which is:
a- Inactive & poorly absorbed.
b- Active & poorly absorbed
c- Inactive & not absorbed
d- Active & absorbed.
192- Mesalazine : is used for the treatment and maintenance of remission of ulcerative colitis.
66
196- Metoclopramide is a dopamine antagonist acts centrally by blocking chemo-
receptor Trigger zone & peripherally acts on GIT to be used as anti-emetic.
203- All of these are the components of calamine lotion B.P. except:
a- ZnO.
b- Calamine.
c- Sodium citrate.
d- Bentonite.
e- Sodium sulphate.
67
205- Which one is not benzodiazepine?
a- Temazepam.
b- Nitrozepam.
c- Loprazolam.
d- Clozapine.
206- Oral rehydrate solution is one of the following:
a- NaCl + K citrate + Na citrate + glucose.
b- Na citrate + KCl + NaCl.
c- Na citrate + KCl + NaCl.
d- NaCl + KCl + NaHCO3 + citric acid.
211- What are the instruction for the patient take Metamucil or any other bulk foaming
laxative as Bran, methyl cellulose and psyllum?
-The adequate fluid intake should be maintained to avoid intestinal obstruction.
68
216- Pharmacokynetic means:
a- Physiological and biochemical effect of the DRUG on the BODY.
b- Physiological and biochemical effect of the BODY on the DRUG.
c- None of the above.
69
227- In a bottle we have NaCl 500 ml, and to obtain we should add what volume of H2O
to get percent dilution 3 (H2O) : 1 (NaCl)?
a- 1500 ml.
b- 2500 ml.
c- 3000 ml.
70
239- All of these are precautions of becotide except:
Used only at the attack of asthma.
246- One of the following preparations used as otic drops for dewaxing:
a- 5% glycerin bicarbonate.
b- 5% alcoholic bicarbonate.
c- Glycerin magnesia.
d- Glycerin phenol.
71
251- Clonidine is used as:
a- Antihypertensive.
b- A drug which prevents the recurrence of migraine.
c- A & B.
d- None of the above.
72
260- All these are antibacterial except:
a- Lomefloxacin.
b- Cefprozil.
c- Cefpodoxime.
d- Zalcitabine.
73
268- Give two side effects of aminoglycosides:
Nephrotoxicity – ototoxicity.
275- Patient with G6 phosphate dehydrogenase deficiency, the drug may cause
haemolysis:
a- Sulphonamide.
b- Paracetamol.
c- Pencillin.
d- Ketoconazole.
74
277- Pentobarbital (often used as pre medication in children) differs from phenobarbital in:
a- Long duration.
b- Faster in action.
75
284- List of the trade name of the following:
Pindolol = Visken.
Baclofen = Lioresal.
Omeprazole = Losec.
Acitretin = Neotigasone.
Isotretinoin = Roaccutane.
Orlistat = Xenical.
Hexoprenaline = Ipradol.
Khellin = Lynamine.
Sildenafil = Viagra.
Pivampicillin = pondocillin.
Bufexamac = Droxaryl.
Codergocrin = hydergine.
Acarbose = Glucobay.
289- What is the difference between retard and entetic coated tablets?
>Retard tablets:
Are coated with a thin layer of different kind of coating agent which make the active
constituent sustained release.
>Enteric coated tablets:
Are dissolved in the intestine and not affected by the stomach juices e.g. anthelmentic.
Passes the stomach & releases in the intestine.
76
292- A child of weight 10 kg. Accidentally swallowed 10 tablets of aspirin and his father
came to you, what can you advice him?
a- Go to a hospital.
b- Give him a medicine.
c- Ignore the case.
d- None of the above.
293- A patient of 10 kg is given a paracetamol one teaspoonful every 4-6 hours, you
should call the doctor to tell him:
a- There is no need to call the doctor.
b- The dose must not exceed 180 mg daily.
c- The dose is not sufficient.
d- The dose is very high.
294- Treatment with an anti arrhythmic drug depends on the following except:
a- Patient sex.
b- Type of medication.
c- Period of medication.
d- Doctors advise.
297- Patient take phenytoin and his hair be less growth. You advice him:
a- Go to doctor.
b- Stop the drug.
c- Give him another drug.
d- This is normal side effect.
298- Roaccutan is prescribed to patient who is women 22 years old, you ask?
a- If she is pregnant.
b- Consult doctor.
c- Give her the drug directly with no questions.
d- None of theabove.
77
300- If you have prescription containing Inderal & the patient is wheezing, what is your
advice?
Call the doctor.
303- A patient has a prescription of Enalapril + KCL, what do you ask him?
a- Which product of KCL do you need?
b- Do you take any other antihypertensive?
c- Do you need syrup or tablet?
d- None of the above.
78
1- drug stored in the body in:
a- fat b- protein
c- connective tissue d- muscle
e- A & B
2- if a drug has the same active ingredient like other drug but not
contain the same inactive ingredient this mean :-
a- Bioequivalent b-pharmaceutical equivalent
c- pharmaceutical alternative
d- A,B
79
8- Following the ethical principle of nonmaleficence requires that pharmacists:
a. respect the rights of patients to make choices.
b. do good to patients, placing the benefit of the patient above all else.
c. avoid, remove or prevent harm from people.
d. act with fairness, allowing people access to pharmacy care.
e. act with honesty, without deception.
14- You should keep the prescription of narcotics in the pharmacy for :
a- two year
b- three years
c- four years
e- five years
17- 6-syncop may occure with the 1st dose of the following :
a_digoxin
b_salbutamol
c_prazosin
d_reserpin
e-clonidin
80
18- Which one is more effective agaienst traveller diarrhea (quinolones have been the
drug of choice) :
a_amoxiciilin
b_ciprofloxacin
c_sulphamethoxasol
d_erythromycin
81
26- the solution contain 9ppm of NaCl the the concevtration of the compound in
the solution:
a- 0.9
b- .09
c- .009
d- .0009
e- .00009
29- Which one used in ventricular arrhthmia with heart block : Phynetoin
82
35- Volatile substance given by inhalation: a) Halothane
39- in tolerance :
patient need more dose to obtain the same effect
83
47- Mizolastine used as :
a- antibiotic
b- anticoagulant
c - anti platlet
d- non sedating -antihistaminic
84
56- Which of the following is found in vitamin b12?
a- Magnesium
b- Nickel
c- Iron
d- Cobalt
e- Manganese
60- for a 4 year old child, the maximum daily dose of paracetamol is :
a- 240mg
b- 480 mg
c- 1 g
d- 2 g
60- To supply the myocardium with O2 shortly after myocardial infarction we give :
a-anticoagulant
b-fibrinolytic
c-aspirin
d-ACEI
85
d- <180/110
63- A hospital on formulating drugs, Efficacy, Work overload, and Costs are taken in
concern. A, B, C, D, and E are antifungal drugs available in the market. All have the
same efficacy. The hospital was using drug E for a period of time. According to the
following data which drug is best to be used by the hospital:
(DRUG COST FREQUENCY DURATION )
A- 3.25 BID 14 DAYS
B- 2.25 ONCE DAILY 14 DAYS
C- 5.5 BID 7 DAYS
D- 2.25 BID 7 DAYS
E- 3.00 QID 7 DAYS
64- Solid dosage forms are better than Solution dosage form because:
a- Accurate dose
b- Easy to handle
c- More stable
d- Faster action
e- a & b and c
86
*Warfarin affects the vitamin K-dependent clotting factors (II, VII, IX,X) ,
whereas heparin and related compounds increase the action of antithrombin on
thrombin and factor Xa .
*73- If we have asolvent costs 150 riyal/kg and its specific gravity =1.07 ,so the
cost for 100 ml of the solvent is?
The sol. almost was: 16.05
76- At 25° C, benzoic acid is much more soluble in benzene (C6H6) than it is in
water. In this situation benzoic acid could be considered to be:
A. Hydrophilic
B. Colloidal
C. Non-polar
D. Polar
E. Both A and D
77- The following properties are similar for both solutions and suspensions:
87
A. The components of both solutions and suspensions can be separated from each
other by physical processes.
b. Solutions and suspensions are composed of two or more components.
C. Solute in the solutions and suspensions settle out over a period of time.
D. Both A and B
E. Both Band C
79- In the treatment of the osteoporosis, which of the following is not correct:
A. alendronate should be taken in the morning 60 min before breakfast
B. calcium and vitamin 0 are essential
C. Hormone replacement therapy (HRT) should be considered in all postmenopausal patients
with osteoporosis .
D. outcome should be assessed with periodic bone density studies
E. raloxifene is selective estrogen modulator that is contraindicated in DVTpatients
83- Which of the following statements describing first dose phenomenon that
associated with prazosin is true?
A. A marked increase in the level of glucose following the initial dose of prazocin.
B. A marked decrease in the level of glucose following the initial dose of prazocin.
C. A marked increase in the level of cholesterol foilowing the initial dose of prazocin.
88
D. A marked postural hypertension 30 to 90 minutes following the initial dose of prazocin.
87- Thiopental is ?
a ) short acting barbiturates
b ) long acting barbiturates
c ) spinal anaesthesia
d ) antihistaminic
e ) antibiotic
89
91- Milironin has following except :
a- +ve inotropic
b- vasodilator
c- increase ca intercellular
d- phosphodiasterase inhibitor
e- potantiate the effect of CAMP
93- How many gm of water add to 5% KCL soln to make 100 gm of solution(w\w)?
a-95
94- Very small molecule(1 part ) soluble in more than 10,000 part of water :
a- fairly soluble b- slightly soluble
C-immiscible d- miscible e- insoluble
95- Which one of the following cause hypertensive crisis if withdrawn suddenly :
a- Clonodine
b- hydrochlorthiazide
c- blocker
g- prazocin
90
101- most potent anti-inflammatory corticosteroid systemically is :
a-cortisone
b-hydrocortisone
c-triamcinolone
d-prednisone
e- dexmethasone
107- Phenylpherin :
a- used in nasal decongestant
b-in high doses stimulate b adrenergic receptor COMT
c- not substrate for chatecholamin o methyltransferase
d-all of the above
e- both a and c
91
110- Enzyme kinetics law:
A - Michaelis–Menten law.
B -henry s law.
C -franks law.
D - Henderson hasselbach law.
E - b&c
92
119- All of these are antichlonergic except :
a- Atropine sulphate
b- Hydroatropine
c- Mebeverine
d- Iprotropium bromide
e- Butrepium bromide
93
1- Terbutaline is used as >>>>>> Antiasthmatic
15- Reserpine mechanism >>>> deplete catecholamines from sympathatic nerve endings
17- Mech.of action hydrochlorothiazide>>> inhibition NACL absorbtion in early distal tube
94
24- The seizures usually involve ( tonic phase )muscle rigidity, followed by
violent muscle contractions( clonic phase) , and loss of alertness
25- Consciousness >>>> its also called grand-mal epilepsy and Pit may be start
with aura or not and it affect both children and adults.
95
sweating
trembling or shaking of the hands or feet
troubled breathing
unusual tiredness or weakness
96
Recommended Dietary Allowances (RDAs) for Vitamin C
Age Male Female Pregnancy Lactation
0–6 months 40 mg* 40 mg*
7–12 months 50 mg* 50 mg*
1–3 years 15 mg 15 mg
4–8 years 25 mg 25 mg
9–13 years 45 mg 45 mg
14–18 years 75 mg 65 mg 80 mg 115 mg
19+ years 90 mg 75 mg 85 mg 120 mg
Smokers Individuals who smoke require 35 mg/day
more vitamin C than nonsmokers.
97
- A, aa., OR aa = of each - comp. = compound, compounded
- a.c. = before meals - dil = dilute
- ad = to, up to - D.C.,dc, or disc. = discontinue
- a.d. = right ear - disp. = dispense
- ad lib. = At pleasure freely - div. = divide, to be divided
- a.m. = morning - dl or dL = deciliter
- amp. = ampoule - d.t.d. = give of such doses
- ante = before - DW = distilled water
- aq. = water - D5W = dextrose% in water
- a.s. = left ear - elix = elixir
- asa = aspirin - e.m.p. = as directed
- a.u. = each ear, both ears - et = and
- b.i.d. = twice daily - ex aq. = in water
- BP = British pharmacopeia - fl or fld = fluid
- BSA = body surface area - fl oz = fluid ounce
- c.or c = with - ft = make
- cp = chest pain - gal = gallon
- D.A.W. described as written - GI = gastrointestinal
- Cc or cc. cubic centimeter - gr or gr = grain
- Gtt or gtt = drop, drops - Non rep. = do not repeat
- H = hypodermic - NPO = nothing by mouth
- h.s. = at bed time - ½ NS = half-strength normal saline
- IM =intramuscular - O = pint
- o.d. = right eye every - o.I. or o.s. = left eye
- IVP = intervenous push - oz. = ounce
- IVPB = intervenous piggyback - o.u. = each eye, both eye
- I or L = litre - p.c. = after meals
- Lb = pound - PDR = Physicians, Desk Reference
- μ = Greek mu - p.o. = by mouth
- M = mix - Ppt = precipitated
- M2 or m2 = square meter - Pr = for rectum
- Mcg, mcg or μg = microgram - Prn or p.r.n. = as needed
- mEq = milliequivalent - Pt. = pint
- mg = milligram - Pulv. = powder
- ml or Ml = milliliter - Pv = vagenal use
- μl or μL = microlitre - q. = every
- N & V = nausea & vomiting - q.d. =every day
- N.F. = National formulary - q.h. = every hour
- Noct. = night, in the night - q.4 hr. = every 4 hours
98
1) 30gm of 1% hydrocortisone mixed with 40 gm 2.5% hydrocortisonen what is
the concentration of the resulting solution?
a) 3% b) 1.85%
c)10% d) none of the above
30gm--------------1% ------------=0.3gm
40gm--------------2.5% --------------=1gm
So, 70gm-------------X%--------------=1.3
So, the con. Result =1.3/70= 0.0185 ×100 = 1.857%
2) A solution is made by dissolving 17.52 g of NaCl exactly 2000 ml. What is the
molarity of this solution?
a- 3.33 b- 0.15 M
c- 1.60 d-3.00 x 10 -4 e-1.6x10 -4
Molarity=moles of solute/volume (L) of solution = milimoles solute / milliliter solution
No. of Moles(mol) = wt (g) / Mwt(g/mol)
So, molecular weight(= molecular mass= molar mass) of NACL=23+34=57
So, Mole=17.52/57=0.307
So, Morality=0.307/2=0.153
% W/W >>>> mass/mass , 1g/100g is 1% w/w
% W/V >>>> mass/volum , 1g/100ml is 1% w/v
% V/V >>>> volum / volum , 1ml/100ml is 1% v/v
w / v = g / ml >> eg.: 4% w/v means 4 gm in 100 ml
99
5% w/w >>> 5 g solute and 95g solvent in each 100g solution
Present by mass = mass of solute /mass of solution ×100
5g/ 100g * 100 = 5 % w/w
5) preperation contin coal tar 30 part , petroleum15 part , zno 150 part. what
conc. of coal tar in 500 ml:-
30 part present in 195ml of prep.
x part present in 500ml of prep.
so, conc. of coal tar in 500ml=30x500/195=76.9 part
6) How many grams needed from drug in one teaspoonful , if 5 one teaspfull
doses contain 7.5 gm of drug ?
a) 0.0005 5 tsp. ------- 7.5 g
b) 0.5 1 tsp. ------- x
c) 500
d) 1.5 g
e) 1500
1 cc = 1 ml = 1 cm3
0.001 * 30 = 0.03 g * 1000 = 30 mg
OR :
0.1 g ------100ml
X ------- 30 ml
( 1:1000 >>> 1/1000 = 0.001 = 0.1%)
100
11) How many milliliters of a NS solution can be made from 4500mg of sodium
chloride ?
a- 0.5 L b- 5L
c- 50 L d- None of the above
12) KI solu. Has 0.5mg/ml dissolve in 30ml water calculate the amount of KI in
the sol. ? (15mg)
0.5mg ------ 1ml
x----------- 30 ml
x = 0.5*30 /1 =15
13) What is The Specific gravity of substance has Weight=Y & the volume is X ?
The Specific gravity =Density of the substance/Density of water
So, the sp. gravity of sub. =weight (Y) /volume(X)/1
So, the sp. gravity of sub. =Y/X
Density( g/ml ) = mass ( g) / volum( ml) or( L)
Density of water = 1g/ml
SG>>> unitless
16) The dose of drug is 0.5ml per day and the total amount of the drug Is 100ml
what is the no. of doses ?
200 doses
NO. = total / size = 100/ 0.5 = 200
17) drug dose is 5 mg present in 1ml & we give 5 doses of one tea spoonful
What is the concentration by mcg?
5 mg ------ 1 ml
X ---------- 25 ml( 5doses* 5 ml)
X = 125 mg * 1000 = 125000mcg
1 tsp. = 5 ml
101
19) Drug X is a given to a 70 Kg patient at an infusion rate of 0.95 mg/kg/hr. How
much drug we need for a 12-hr infusion bottle if the patient weight is 70 kg:
A. 798 mg B. 66.5 mg
C. 840 mg C. 665 mg
D. 84 mg
> 70* 0.95* 12 =798 mg
20) An elixir contains 0.1 mg of drug X per ml. HOW many micrograms are there
in one tsp of the elixir :
A. 0.0005 micrograms B. 0.5 micrograms
C. 500 micrograms D. 5 micrograms
E. 1500 micrograms
0.1 ------- 1ml
x----------- 5ml
x= 0.5 *1000= 500 mcg
21) How many gm of water add to 5% KCL sol. to make 180gm of solution(w\w)?
5gm--------------100
Xgm--------------180
X= 5x180/100=9 gm of kcl
So, the amount of water is:-
180 - 9 =171 gm
22) A patient’s cholesterol level is equal to 4mM/L. This cholesterol level can be
expressed in terms of mg/dL. (molecular weight of cholesterol = 386)
A. 0.0154 mg/dL B. 0.154 mg/dL
C. 1.54 mg/dL D. 15.4 mg/dL
E. 154 mg/dL
24) A 500 infusion bottle contains 11.729mg of potassium chloride (KcI). How
many mEq of KCI are present? The molecular weight of KCI = 74.6 :
A. 0.1571 mEq
B. 1571 mEq
102
C. 6.37 mEq
D. 0.00637 mEq
E. 1.72 mEq
To convert (mg) to ( mEq):
mEq = mg * valence / Mwt
= 11. 729 *1 / 74.6 = 0.157 mEq
26) If we have solvent costs 150 riyal / kg & its specific gravity= 1.07 so the cost
for 100 ml of solvent is ?
SG = density
Density = mass (g) / volum (ml)
1.07 = mass / 100ml >>> mass = 1.07 * 100 = 107 g / 1000 = 0.107 kg
150 * 0.107 = 16.05 riyal
27) 0.8687g cacl2 in 500 ml solvent , density of the solvent 0.95 g/cm3 , find the
MOLALITY ?
a- 0.0165 Molal # ( molar >>M , molal >> m )
b- 0.0156 Molal
c- 0.0165 m
d- 0.0230 m
e- 0.0156 m
Mass= density * volum >> = 0.95 * 500 = 475 g /1000 = 0.475 kg Of solvent .
Moles = 0.8687g/ 111( mwt of cacl2) =0.0078mol
Molality = 0.0078 / 0.475 = 0.0165 molal
28) The molal concentration of solution 0.559 M is , ( Mwt = 331.23 g / mole &
density of solution = 1.157 g/ml ) ?
a- 1.882
b- 0.882
c- 0.559
d- 0.575 molal
103
2- find the total mass of solution :
Mass= density * volum >> 1.157 g/ml * 1000 ml = 1157g of solution
3- calculate the grams of solute :
0.559 M >> means 0.559 moles of solute per 1 L of solution
( convert 0.559 moles to grams)
Mass= mol * mwt = 0.559 * 331.23g/mol = 185.16 g of solute
4- calculate the grams of the solvent :
1157 g of solution – 185.16 g of solute = 971.84 g of solvent
5- calculate the molality :
0.559 moles / 0.97184 kg solvent = 0.575 molal
29) The solution contain 9ppm of NaCl the the concentration of the compound in
the solution ?
a- 0.9
b- .09
c- .009
d- .0009%
e- .00009
30) How many gm of water add to 5% KCL soln to make 100 gm of solution
(w\w)?
95 g
31) Drug container contain 90 mg each tablet contain 0.75mg. how man doses?
90 / 0.75 = 120 doses
32) Sol. contain D5W another one contain D50W we want to prepare sol. contain
D15W its volum is 450ml. How much ml we need of each sol. ??
50% 10
15%
5% 35
------------
45
50% >> 10 / 45 * 450 = 99.99ml >> 100 ml
5% >> 35 /45 * 450 = 350 ml
ﻣﺠﻤﻮﻋﮭﻢ450 ml
ﻣﻞ350 ------ %5 *ﯾﻌﻨﻲ ﻧﺄﺧﺬ ﻣﻦ
ﻣﻞ100 -------- % 50 و ﻣﻦ
10:35 اﻟﻨﺴﺒﮫ
Or: 1: 3.5
104
33) Sol. contain D5W another one contain D50W we want to prepare sol. cotain
D15W its volume is 450ml. How much ml we need of each sol. ??
5% ---------------------------------- 35
15%
50% -------------------------------- 10
50 ﻣن ﺗرﻛﯾز100 ﻣﻊ%5 ﻣن ﺗرﻛﯾز350 اﻟﻣﻔروض ﻧﺧﻠط3.5:1 ﯾﻌﻧﻰ10 : 35 اﻟﻧﺳﺑﺔ%
34) The dose of paracetamol for 3 month children to one year old child is :
a- 120 – 250 mg / 4-6 hours daily
b- 250 – 500 mg / 4-6 hours daily
c- 60 – 120 mg / 4-6 hours daily
d- 20 – 60 mg / 4-6 hours daily
i- 500 – 1000 mg / 4-6 hours daily
35) A child who came with prescription for paracetamol (whose weight is 12 Kg )
and dose ( 5 ml Q4H to Q6H PRN ) you are going to tell the doctor to tell him :
a- The dose is too high as the daily dose is 5 mg / kg
b- The dose is adequate but frequency should be Q6H only
c- The dose is small and a dose of a 180 mg is required
d- The dose is inadequate and no need to call the doctor
e- The dose is adequate but frequency should be Q4H only
paracetamol>> 10 mg / kg / dose
120 mg for every 5ml
10 mg ------- 1kg
x------------- 12 kg
x= 120 mg = 5ml
105
c- 60 ml
d- 30 ml
e- 15 ml
39) How many gram of magnesium oxide are required to make 300 ml of 15%
(W/V) solution ?
a- 15
b- 30
c- 45g
d- 60
e- 75
*40) How much sodium chloride is required to prepare 500 ml of 0.9% normal
saline ?
a- 0.45 grams
b- 4.5 milligrams
c- 450 milligrams
d- 4500 milligram
e- 4.5 grams
42) Grains :
a- 65 gm
b- 6.5 gm
c- 0.065 gm
d- 0.0065 gm
e- None of the above
106
45) Nurse ask you to dilute 3 ml lidocain 1% to 1: 1000. How many ml of water
you will need ?
a- 100 ml
b- 10 ml
c- 30 ml
d- 300 ml
e- 3 ml
C1 x V1 = C2 x V2
C1>> conc. Of starting solution
V1>> volume of starting solution need to make new solution
C2>> final conc. Of new solution
V2>> final volume of new solution
>>>>> 1 % * 3 ml = 1: 1000 * v2
V2 = 30 ml
V2 – v1 = 30 - 3 = 27 ml of water
46) Solution of 160 ml containing 5% NaCl how much water in this solution ?
a- 100 ml
b- 152 ml
c- 135 ml
d- 8 ml
e- 130 ml
0.05 * 160 = 8g
160 - 8 = 152 ml of water
49) Patient use (Augmentin 250 mg Tablets) three time daily for one week. How
many tablet this patient will consume ?
(a) 20 tablet
(b) 21 tablet
(c) 18 tablet
(d) 9 tablet
(E) 24 tablet
3* 7 = 21
107
50) Patient take drug A (250 ml/5mg). he take 1000 ml a.m. 750 ml p.m. How he
will receive in 20 days in mg ?
(a) 700 mg
(b) 1250 gm
(c) 1000 gm
(d) 600 gm
(E) 900 gm
51) Antiseptic contain 150 ml of active ingrident with supply label 5mg for 10 ml
How many mg of active ingrident in 150 ml ?
(a) 75 mg
(b) 15 mg
(c) 1500 mg
(d) 50 mg
(E) 100 mg
5 mg--------10ml
x-----------150 ml
54) How many gram needed from water to prepare 160 gram from potassium
acetate (5 % W/W) ?
(a) 100
108
(b) 130
(c) 135
(d) 152g
(E) 125
55) How many gram needed from substance (X) to prepare 30 ml solution
(1:1000) ?
(a) 10 mg
(b) 30 mg
(c) 300 mg
(d) 0.03 mg
(E) 1000 mg
56) If 100 mg of the drug is administered orally and 70mg of this drug is absorbed
unchanged the bioavailability is ?
(a) 100 %
(b) 10 %
(c) 70 %
(d) 30 %
(E) 90 %
57) You find 20 ml vial of aminophylline with supply labeled 20mg/ml How many
mg in the vial??
a) 200mg
b) 400mg
c) 600mg
d) 800mg
e) 1 gm
20 mg ------1 ml
X mg-------20 ml
58) You find 20 ml vial of aminophylline with supply labeled 20mg/ml How many
ml must to be injected to supply patient with 100mg??
a) 6 ml
b) 10 ml
C) 5 ml
D) 20 ml
e) 25 ml
20 mg ------1 ml
100 mg ---- x ml
109
60) Dilute avail of tetracycline for aqueous injection labeled 10000 I.U To obtain
dose of 5000 I.U using water for injection 10 ml ??
a) 4 ml
b) 5 ml
c) 6 ml
d) 7 ml
e) non of the above
10000 iu--------10 ml
5000 iu---------x
64) Drug infusion rate is 2mg\kg\hr , infused for 12 hours , for 70kg patient. what
is total dose?
(2x70x12)=1680 mg
66) In a bottle we have NaCl 500 ml, and to obtain we should add what volume
of H2O to get percent dilution 3 (H2O) : 1 (NaCl)?
a- 1500 ml.
b- 2500 ml.
c- 3000 ml.
500-------1
x---------3
110
67) How much lidocaine for solution of 1/1000 to obtain 30 cc ?
a- 0.03.
b- 0.3.
c- 30mg
d- None of the above.
70) 2 L glucose solution contains 72g glucose. If glucose has molar mass of 180g/mol
, What is the molarity of glucose solution?
a- 0.2M
b- 5M
c- 36 M
d- none of the above
72) How many mgs. of substance (x) required to prepare 30 ml solution (1:1000)?
a- 10 mg
b- 30 mg
c- 300 mg
d- 0.03 mg
# L water = kg water
73) 100 gms of source ( C12H22011, mol.wt.=342.3 g/mol) are dissolved in 1.5 L
of water (density of water = 1g/ml). what is the molality ?
a- 0.19 m
b- 1.9 m
c- 0.019 m
d- None of the above
74) How much amount of water added to 250ml of sol. as 1/500 of benzonium
chloride to be 1/2000 ?
a- 0.125 L
b- 0.250 L
111
c- 0.4 L
d- 2 L
e- 4 L
C *v = c* v
1: 2000 * v = 1: 500* 250
V= 1000ml solution
1000- 250 = 750 ml water = 0.75 L
2 *
75) Amoxil 500 mg taken t.i.d the total capsules taken for a week equal :
21
80) Drug container contain 90 mg each tablet contain 0.75mg. how many
doses?
90 / 0.75 = 120 doses
112
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