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Drug Study

Name of Drug Mechanism of Indication Contraindication Side Effects Nursing Responsibility


Action
Generic Name: Action: Binds to 50S Therapeutic Hypersensitivity to CNS: Dizziness, Assessment
Azithromycin ribosomal subunits outcome: azithromycin, headache, vertigo,  Assess for signs and
(ay-zi-thro-my’sin) of susceptible Bacteriostatic against erythromycin or any somnolence symptoms of infection:
bacteria and the following macrolide drainage, fever,
Brand Name: suppresses protein organisms: Monazella CV: Palpitations, increased white blood
Zithromax, Zmax synthesis; much catarrblis, chest pain cell (>10,000/mm3),
greater spectrum of Streptococcus Precautions: urine culture positive,
Functional class: activity than pneumoniae, Pregnancy category EENT: Hearing sore throat, sputum
Antiinfective erythromycin; more Streptococcus B, breastfeeding, loss, tinnitus culture positive
effective against pyogenes, child under 6  Monitor respiratory
Chemical class: gram-negative Staphylococcus months for otitis GI: Nausea, status: rate, character,
Macrolide (azalide) organisms aureus, Haemophilus media, child under 2 vomiting, diarrhea, wheezing, tightness in
influenza, years for hepatotoxicity, chest; discontinue
Pregnancy Clostridium, pharyngitis, abdominal pain, product if these occur
category: Legionella geriatric, stomatitis,  Monitor allergies
B pneumophila, renal/hepatic/cardiac heartburn, before treatment,
Chlamydia disease, tonsillitis dyspepsia, reaction of each
Dosage and routes: trachomatis, flatulence, melena, medication; place
Intravenous Mycoplasma; cholestatic allergies on chart,
jaundice, notify all people
Oral No effect on pseudomembranous giving products; skin
. methicillin-resistant S. colitis, tongue eruptions, itching
aureus; discoloration  Monitor intake and
output ration, renal
in children: acute GU: Vaginitis, studies; report
otitis media (H. moniliasis, nephrtis hematuria, oliguria in
influenzae, M. renal disease; check
catarrbalis, S. HEMA: Anemia urinalysis, protein,
pneumonia) PO, blood
 Monitor liver studies:
AST, ALT, bilirubin,
Drug Study

Acute INTEG: Rash, LDH, alkaline


pharyngitis/tonsillitis urticarial, pruritus, phosphatase; CBC
(group A photosensitivity with differential
streptococcal) PO;  Monitor bowel pattern
SYST: before, during
Acute skin/soft tissue Angioedema treatment
infections (PO);  Assess for
superinfection: sore
Community acquired throat. Mouth, tongue;
pneumonia (C. fever, fatigue,
pneumonia, H. diarrhea, anogenital
influenza, M. pruritus
pneumonia, S.
pneumonia) PO; Nursing Diagnosis
 Diarrhea (adverse
Pharyngitis/tonsillitis reaction)
(S.pyogenes)  Risk for infection
 Knowledge deficit
Uses: Mild to Implementation
moderate infections of  Provide adequate
the upper respiratory intake of fluids (2L)
tract, lower during diarrhea
respiratory tract; episodes
uncomplicated skin
 Give with a full glass
and skin structure of water, give susp 1
infection, hour before or 2 hours
nongonococcal after meals; tablet may
urethritis, or be taken without
cervicitis; prophylaxis regard to food; do not
of disseminated give with fruit juices
Mycobacterium avium
 Store at room
complex (MAC)
temperature
Drug Study

 Reconstitute 1g packet
for susp with 60ml
water, mix, rinse glass
with more water and
have patient drink to
consume all
medication; packets
not for pediatric use
 Do not take
aluminum/magnesium
containing antacids or
food simultaneously
with this product

Patient/family education
 Instruct patient to report
sore throat, black furry
tongue, fever, loose foul-
smelling stool, vaginal
itching, discharge,
fatigue; may indicate
superinfection
 Caution to patient not to
take
aluminum/magnesium-
containing antacids or
food simultaneously
with this product; blood
levels or azithromycin
will be decreased
 Instruct patient to notify
prescriber of diarrhea
stools, dark urine, pale
stools, yellow
discoloration of eyes or
Drug Study

skin, severe abdominal


pain; cholestatic
jaundice is a sever
adverse reaction
 Teach patient complete
dosage regimen
 Teach patient to notify
doctor if pregnancy is
suspected
 Inform patient that
sunburns may occur;
wear protective clothing
and sunscreen

Evaluation
Positive therapeutic
outcome
 WBC within 5,000-
10,000/mm3
 Culture and sensitivity
negative for infection