Drug Study

Name of Drug Mechanism of Indication Contraindication Side Effects Nursing Responsibility

Action
Generic Name: Action: Binds to 50S Therapeutic Hypersensitivity to CNS: Dizziness, Assessment
Azithromycin ribosomal subunits outcome: azithromycin, headache, vertigo,  Assess for signs and
(ay-zi-thro-my’sin) of susceptible Bacteriostatic against erythromycin or any somnolence symptoms of infection:
bacteria and the following macrolide drainage, fever,
Brand Name: suppresses protein organisms: Monazella CV: Palpitations, increased white blood
Zithromax, Zmax synthesis; much catarrblis, chest pain cell (>10,000/mm3),
greater spectrum of Streptococcus Precautions: urine culture positive,
Functional class: activity than pneumoniae, Pregnancy category EENT: Hearing sore throat, sputum
Antiinfective erythromycin; more Streptococcus B, breastfeeding, loss, tinnitus culture positive
effective against pyogenes, child under 6  Monitor respiratory
Chemical class: gram-negative Staphylococcus months for otitis GI: Nausea, status: rate, character,
Macrolide (azalide) organisms aureus, Haemophilus media, child under 2 vomiting, diarrhea, wheezing, tightness in
influenza, years for hepatotoxicity, chest; discontinue
Pregnancy Clostridium, pharyngitis, abdominal pain, product if these occur
category: Legionella geriatric, stomatitis,  Monitor allergies
B pneumophila, renal/hepatic/cardiac heartburn, before treatment,
Chlamydia disease, tonsillitis dyspepsia, reaction of each
Dosage and routes: trachomatis, flatulence, melena, medication; place
Intravenous Mycoplasma; cholestatic allergies on chart,
jaundice, notify all people
Oral No effect on pseudomembranous giving products; skin
. methicillin-resistant S. colitis, tongue eruptions, itching
aureus; discoloration  Monitor intake and
output ration, renal
in children: acute GU: Vaginitis, studies; report
otitis media (H. moniliasis, nephrtis hematuria, oliguria in
influenzae, M. renal disease; check
catarrbalis, S. HEMA: Anemia urinalysis, protein,
pneumonia) PO, blood
 Monitor liver studies:
AST, ALT, bilirubin,
 Drug Study

Acute INTEG: Rash, LDH, alkaline

pharyngitis/tonsillitis
(group A
streptococcal) PO;
Acute skin/soft tissue
infections (PO);
Community acquired
pneumonia (C.
pneumonia, H.
influenza, M.
pneumonia, S.
pneumonia) PO;
Pharyngitis/tonsillitis
(S.pyogenes)
Uses: Mild to
moderate infections of
the upper respiratory
tract, lower
respiratory tract;
uncomplicated skin
and skin structure
infection,
nongonococcal
urethritis, or
cervicitis; prophylaxis
of disseminated
Mycobacterium avium
complex (MAC)
urticarial, pruritus, phosphatase; CBC
photosensitivity with differential
 Monitor bowel pattern
SYST: before, during
Angioedema treatment
 Assess for
superinfection: sore
throat. Mouth, tongue;
fever, fatigue,
diarrhea, anogenital
pruritus
Nursing Diagnosis
 Diarrhea (adverse
reaction)
 Risk for infection
 Knowledge deficit
Implementation
 Provide adequate
intake of fluids (2L)
during diarrhea
episodes
 Give with a full glass
of water, give susp 1
hour before or 2 hours
after meals; tablet may
be taken without
regard to food; do not
give with fruit juices
 Store at room
temperature
Drug Study

 Reconstitute 1g packet
for susp with 60ml
water, mix, rinse glass
with more water and
have patient drink to
consume all
medication; packets
not for pediatric use
 Do not take
aluminum/magnesium
containing antacids or
food simultaneously
with this product

Patient/family education
 Instruct patient to report
sore throat, black furry
tongue, fever, loose foul-
smelling stool, vaginal
itching, discharge,
fatigue; may indicate
superinfection
 Caution to patient not to
take
aluminum/magnesium-
containing antacids or
food simultaneously
with this product; blood
levels or azithromycin
will be decreased
 Instruct patient to notify
prescriber of diarrhea
stools, dark urine, pale
stools, yellow
discoloration of eyes or
Drug Study

skin, severe abdominal

pain; cholestatic
jaundice is a sever
adverse reaction
 Teach patient complete
dosage regimen
 Teach patient to notify
doctor if pregnancy is
suspected
 Inform patient that
sunburns may occur;
wear protective clothing
and sunscreen

Evaluation
Positive therapeutic
outcome
 WBC within 5,000-
10,000/mm3
 Culture and sensitivity
negative for infection