A.

 Boediono  /  Morula  Indonesia   4/2/18  

Teknologi  pemilihan  sperma  sampai  6000x   IMSI  

(Intracytoplasmic  Morphologically  Selected  Sperm  Injec8on)  
•  Memungkinkan  untuk  menghindari  pemilihan  
sperma  dengan  kualitas  buruk  yang  Bdak  terlihat  
dengan  metode  ICSI  

à  Sperma  dengan  kelainan  

berupa  ‘vacuole’  berkorelasi  
terhadap  kelainan  kroma8n  
6000x   selama  proses  maturasi  sperma  
400x  
200x  
100x  

IMSI  vs  ICSI    

Spindle Imaging System:
pada  pasien  yang  pernah  gagal  IVF    

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A.  Boediono  /  Morula  Indonesia   4/2/18  

ICSI  vs  IMSI   Witness  in  every  treatment…  

100%  
90%  
80%   71%   ICSI   IMSI  
70%   67%  
60%   52%  
50%   42%  
40%  
29%  
30%  
21%  
20%   16%  
10%  
10%  
0%  
FerBlizaBon  Rate   Quality  D3  Rate   Quality  D5  Rate   Pregnancy  Rate  

Time  Lapse  Incubator   Time  Lapse:  VIP  Incubator  

Miri  TL  =  
Multi-­‐Room  Incubator  Time  Lapse  

+   =  

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A.  Boediono  /  Morula  Indonesia   4/2/18  

Embryo  Biopsy  

PRE-IMPLANTATION
GENETIC SCREENING
(PGS)  
} 
Day-­‐3  Embryo  

Cleavage  stage:    
Blastocyst  Embryo  

 Biopsy  on  the  morning  on  day  3  post-­‐inseminaBon  is  recommended  

}  Blastocyst  stage:    
 Blastocyst  biopsy  on  the  morning  of  day  5  or  6  post-­‐inseminaBon.  

       Lab.  Molecular  GeneBc:        Lab.  Molecular  GeneBc:  

Biopsy   Sample     Electro-­‐

PCR  for  Whole   Labeling  
Cell  lysis   phoresis  
Genome  
AmplificaBon  

Analysis  and  report   Scanning   HybridizaBon  

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A.  Boediono  /  Morula  Indonesia   4/2/18  

Keberhasilan Kehamilan setelah PGS

Pregnancy  rate  indicated  is  as  of  20  weeks  aaer  IVF  cycle  

Keberhasilan  Kehamilan  berdasarkan  

     Upaya  mendapatkan  Bayi  Sehat  
Jumlah  Embrio  yang  Ditransfer:  
MulBple  ET  
49.28   à  MulBple  pregnancy  
<  35  tahun   >  35  tahun  
42.71  

33.33   31.4   Single  selected  ET  

22.22    à  SIngleton  pregnancy  
11.67  

CryopreservaBon  
1  Embrio   2  Embrio   3  Embrio  

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A.  Boediono  /  Morula  Indonesia   4/2/18  

Pembekuan (kriopreservasi):   Viabilitas  Embrio  setelah  Pembekuan:  

ü  Sperma  
ü  Sel  telur  
ü  Embrio  
93.86%  
•  Penyimpanan yang aman
•  Dapat digunakan setiap saat
diperlukan 68.97%  

Slow  freezing   VitrificaBon  

Kembar  Sehat  (beda  umur):   Assisted Hatching (AH)

精子

Setelah 5 tahun
menanti….

…When Dreams
Come True

5  
A.  Boediono  /  Morula  Indonesia   4/2/18  

Keberhasilan  Kehamilan  setelah    

Assisted  Hatching  (AH)  
Morula  IVF  Indonesia  

49.33  

44.17  

AH   NO-­‐AH  

certificate of registration Kunjungi  Website  kami:  

To
Reproductive Technology Accreditation Committee Code of
Practice for Assisted Reproductive Technology Units
hIp://www.morulaivf.com  
(International Edition, 2014)

THIS IS TO CERTIFY THAT

Reproductive Technology
Accreditation Committee
Morula IVF Jakarta
Jl. Teuku Cik Ditiro
No.12, Jakarta
10350
Indonesia

Has been assessed and registered as complying with the requirements of the Fertility
Society of Australia’s Code of Practice for Assisted Reproductive Technology Units
International Edition (2014) for the following scope. Further clarifications regarding the
•  Standar  internasional  dari  
Australia  
scope of this certificate and the applicability of RTAC requirements may be obtained by
consulting the organisation.

Fertility Treatment
•  Pertama  dan  satu2  klinik  bayi  
Di Wilde Registration Number: PRD/R62/0301
tabung  di  Indonesia  yang  telah  
diakui  layak  sesuai  standar  
Director Operations Registration Date: 12/Aug/2016
www.jas-anz.org/register ISC Pty Ltd, A.B.N. 45 071 810 949 Expiry Date: 12/Aug/2019

ISC (a DNV GL Company), Level 4,181 Miller Street, North Sydney NSW 2060, Australia.

This certificate is valid until the Expiry Date on the condition that audits are conducted and paid
for as per the Certification Agreement. Should this condition not be met, cancellation procedures
will be initiated and the client will be removed from the JAS-ANZ register. This Certificate
Internasional  
remains the property of International Standards Certifications Pty Ltd – A DNV-GL Company
and must be returned upon request. It must not be altered in any way. Intentional misuse of this
certificate will result in cancellation without prior notification.
•  Jaminan  atas  kualitas  

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