According to Philippine Diabetes Statistics, around 20% of Filipinos are suffering from

diabetes. (All About Diabetes, 2012). Of those suffering from diabetes, people are mostly of
working age. (IDF, 2015). Its complication is not only persistent hyperglycemia, but also includes
other long-term complications, to wit: cardiovascular, peripheral vascular, ocular, neurologic and
renal abnormalities, which are responsible for morbidity, disability and premature death in young
adults. In the Philippines alone, there were about, for the record in 2015, 51,197 deaths related to
diabetes.1 Moreover, it is said to be among the top ten leading causes of deaths across the globe.2
With the growing number of amputation, blindness, and other complications of diabetes,
its causes are attributable to many factors. It is often attributed to the eating habit or even lifestyle
which results to obesity. However, after thoroughly considering a part of the many causes of
diabetes, genetic association might have had the ultimate cause, and probably the solution as well,
of such disease. In fact, in a study made by The Danish Diabetes Association, Pociot and Dermott
said that with genome screening, there would be a dominant protection from the disease.3
Of different kinds of diabetes, Heterogeneous Type 2 DM, accounting for about 85% of all
diabetic patients, is supposed to be induced by multiple genes defects involved in insulin action
and/or insulin secretion. Other genetically influenced traits like obesity and hyperlipidemia are
strongly associated with the Type 2.4

1
IDF. (2015). Retrieved from https://www.idf.org/component/attachments/attachments.html. Retrieved:
September 21, 2017
2
WHO. (2015). Retrieved from http://www.who.int/gho/countries/phl.pdf. Retrieved: September 21, 2017)
F. Pociot and M F McDermott. (2002). Genetics of type 1 diabetes mellitus.
http://www.nature.com/gene/journal/v3/n5/full/6363875a.html. Retrieved: September 21, 2017)
E. Marklova. (2001) Genetic Aspects of Diabetes Mellitus. Retrieved from
http://www.ncbi.nlm.nih.gov/pubmed/11367889. Retrieved: September 21, 2017

All About Diabetes. (2012). Retrieved from http://www.allaboutdiabetes.net/philippine-diabetes-statistics/

Retrieved: September 21, 2012
Diabetes Research and Clinical practice (2016). Retrieved from http://www.ClinicalKey.com. Retrieved: September
20, 2017
WHO. Retrieved from http://www.who.int/genomics/about/Diabetis-fin.pdf. Retrieved: September 21, 2017)
IDF. (2015). Retrieved from https://www.idf.org/component/attachments/attachments.html. Retrieved:
September 21, 2017
WHO. (2015). Retrieved from http://www.who.int/gho/countries/phl.pdf. Retrieved: September 21, 2017)
F. Pociot and M F McDermott. (2002). Genetics of type 1 diabetes mellitus.
http://www.nature.com/gene/journal/v3/n5/full/6363875a.html. Retrieved: September 21, 2017)
E. Marklova. (2001) Genetic Aspects of Diabetes Mellitus. Retrieved from
http://www.ncbi.nlm.nih.gov/pubmed/11367889. Retrieved: September 21, 2017