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Shainne L.

Reyes Oct 2, 2018


BSN301/Grp3 Prof. Lauro

Drug Study

Side effects/ Adverse Nursing


Drug Indication Contraindication Drug Action
Effects Responsibilities
Generic Name: Indicated in patients with Hypersensitive to Works by inhibiting the  Pain -Assess patient’s
Ceftriaxone neurologic complications, cephalosporins, mucopeptide synthesis in the  Induration previous sensitivity
carditis and arthritis. It is penicillins and bacterial cell wall. The beta-  Phlebitis reaction to penicillin
also effective in Gram related antibiotics. lactam moiety of Ceftriaxone  Rash or other
Brand Name: negative infections; binds to carboxypeptidases,  Diarrhea cephalosphorins.
Forgram Route and Meningitis, Gonorrhea. It endopeptidases, and  Thrombocytosis Assess patient for
Dosage: 1 gram TIV drip is also for Bone and joint transpeptidases in the  Leucopenia signs and symptoms
q12 infections, Lower bacterial of infection before
 Glossitis
respiratory tract infections, cytoplasmicmembrane. and during the
 Respiratory super
Classification: 3rd middle ear infection, PID, These enzymes are involved treatment
infections
generation Septicemia and Urinary in cell-wall synthesis and cell -Obtain C&S before
cephalosphprin Tract infections. division. By binding to these beginning drug
enzymes, Ceftriaxone results therapy to identify if
in the formation of of correct treatment has
defective cell walls and cell been initiated.
death. -Report signs such
as petechiae,
ecchymotic areas,
epistaxis or other
forms of unexplained
bleeding.
-Monitor hematologic,
electrolytes, renal
and hepatic function.
-Assess for possible
upper infection:
itching fever,
malaise, redness
Drug Study

Side effects/
Drug Indication Contraindication Drug Action Nursing Responsibilities
Adverse Effects
Generic Name: Treatment of infection of Hypersensitivity to Prevents bacterial cell wall  Vomiting -Advise the patient’s family
Amoxicillin respiratory tract, skin & skin penicillins, synthesis during replication.  Nausea to take the medication with
structures, genitourinary cephalosparins, or Bactericidal.  Abdominal meals for better absorption
Brand Name: tract, otitis media, imipenem. Not used to pain & to reduce GI discomfort.
Amoxil Route and meningitis, septicemia, treat severe  Diarrhea -Instruct the patient’s family
Dosage: 500mg tablet, 1 sinusitis, bacterial pneumonia,  Rash to take medication as
tab PO q8 endocarditis prophylaxis. empyema,  Pruritus prescribed even after
bacteremia,  Urticaria feeling better and not to
Classification: pericarditis, meningitis double dose.
Anti-infective Drug and purulent or septic -Teach the patient’s family
arthritis during acute to report sore throat,
stage. bruising, bleeding and joint
pain, this may indicate
blood dyscrasias.
-Advise patient’s family to
watch out for perineal
itching, fever, malaise,
redness, pain, swelling,
drainage, rash, diarrhea,
change in cough, sputum
or furry tongue, this may
indicate super infection.
-Advise patient’s family to
report bloody, mucoid
diarrhea which may
indicate
pseudomembranous colitis
Drug Study

Side effects/ Adverse Nursing


Drug Indication Contraindication Drug Action
Effects Responsibilities
Generic Name: Indicated in patients with Hypersensitive to Works by inhibiting the  Pain -Assess patient’s
Ceftriaxone neurologic complications, cephalosporins, mucopeptide synthesis in the  Induration previous sensitivity
carditis and arthritis. It is penicillins and related bacterial cell wall. The beta-  Phlebitis reaction to penicillin or
also effective in Gram antibiotics. lactam moiety of Ceftriaxone  Rash other cephalosphorins.
Brand Name: negative infections; binds to carboxypeptidases,  Diarrhea Assess patient for
Forgram Route and Meningitis, Gonorrhea. It is endopeptidases, and  Thrombocytosis signs and symptoms
Dosage: 1 gram TIV drip also for Bone and joint transpeptidases in the  Leucopenia of infection before and
q12 infections, Lower bacterial during the treatment
 Glossitis
respiratory tract infections, cytoplasmicmembrane. These -Obtain C&S before
 Respiratory
Classification: 3rd middle ear infection, PID, enzymes are involved in cell- beginning drug
super infections
generation Septicemia and Urinary wall synthesis and cell therapy to identify if
cephalosphprin Tract infections. division. By binding to these correct treatment has
enzymes, Ceftriaxone results been initiated.
in the formation of of defective -Report signs such as
cell walls and cell death. petechiae, ecchymotic
areas, epistaxis or
other forms of
unexplained bleeding.
-Monitor hematologic,
electrolytes, renal and
hepatic function.
Assess for possible
upper infection: itching
fever, malaise,
redness
Drug Study

Nursing
Drug Indication Contraindication Drug Action Drug Interaction
Responsibilities
Brand Name: Multivitamins are used to The body needs these Multivitamins can -Find out the types,
Estroven provide vitamins that are Iron Metabolism Disorder nutrients for interact with certain amounts, and reason
not taken in through the causing Increased Iron reproduction, medications, or affect for using them.
diet. Multivitamins are also Storage maintenance, growth how medications work in -Gather information
Generic used to treat vitamin and regulation of bodily your body. The following about the ingredient
Name: Multivitamins deficiencies (lack of Increased Bodily Iron from processes. drugs: list on these
vitamins) caused by illness, High Red Blood Cell supplements and look
pregnancy, poor nutrition, Destruction Multivitamins may tretinoin or isotretinoin; for contraindications to
digestive disorders, and contain many of these an antacid; their use.
many other conditions. Hemolytic Anemia vitamins and minerals, an antibiotic; -Direct patients to
but in varying forms and a diuretic or "water pill"; reputable websites for
Ulcer from Stomach Acid amounts. They can also heart or blood pressure information on drug-
contain other medications; nutrient interactions
Ulcerated Colon ingredients like herbs, a sulfa drug; or and other
amino acids and fatty NSAIDs (nonsteroidal contraindications to
Inflammation of the Lining of acids. anti-inflammatory supplement use.
the Stomach and Intestines drugs)--ibuprofen (Advil,
Motrin), naproxen
Several Blood Transfusions (Aleve), celecoxib,
diclofenac,
indomethacin,
Diverticular Disease
meloxicam, and others.
Drug Study

Nursing
Drug Indication Contraindication Drug Action Drug Interaction
Responsibilities
Brand Name: Maalox Calcium is indicated for Essential for nervous, Hypercalcemia -Monitor VS
hypocalcemia (e.g. in Calcium salts are muscular, and skeletal increases the risk of especially BP and PR.
neonates and for contraindicated in patients systems. Maintain cell digoxin toxicity. Chronic - Obtain ECG result.
Generic hypocalcemic tetany). with ventricular fibrillation or membrane and use with antacids in -Asses for heartburn,
Name: Calcium Intravenously administered hypercalcemia. Intravenous capillary permeability. renal insufficiency may indigestion,
Carbonate calcium is also used for administration of calcium is Act as an activator in lead to milk-alkali abdominal pain.
hyperkalemia, contraindicated when serum the transmission of syndrome. Ingestion by -Monitor serum
hypermagnesemia, and calcium levels are above nerve impulses and mouth may decrease calcium before
during bypass operations. normal. contraction of cardiac, the absorption of orally treatment
Its use as an emergency skeletal and smooth administered -Assess for nausea
measure for cardiac arrest muscles. It is essential tetracyclines, and vomiting,
has not been sufficiently for bone formation and fluoroquinolones, anorexia, thirst,
demonstrated. blood coagulation. It is phenytoin, and iron severe constipation
also used a salts. Excessive
Calcium carbonate replacement of calcium amounts may decrease
neutralizes gastric acids in deficiency states. It the effects of calcium
and is well suited for the controls of channel blockers,
treatment of hyperphosphatemia in atenolol. Concurrent
hyperphosphatemia in end-stage renal use with diuretics may
dialysis patients. The disease without result in hypercalcemia
administration of aluminium promoting aluminum
hydroxide can thus be absorption
partially avoided.
Drug Study
Nursing
Drug Indication Contraindication Drug Action Drug Interaction
Responsibilities
Brand Name: Arthinol, Mild to moderate pain or Blocks pain impulses in Daily use of NSAIDs -Liver function studies:
fever including rheumatoid Hypersensitivity salicylates CNS inhibition of (such as ibuprofen) may AST,ALT, bilirubin,
Generic Name: Aspirin arthritis, osteoarthritis, tatrazin, GI bleeding, bleeding prostaglandin decrease aspirin's ability creatinine if patient is on
thromboembolic disorders, disorders, children <12 yr, synthesis; antipyretic to prevent heart long term therapy
Classifications : transient ischemic attacks, children with flulike symptoms, action results from attack/stroke. If you are -Renal function studies:
Nonnarcotic analgesic, rheumatic fever, post pregnancy (3rd trimester), vasodilation of taking low-dose aspirin BUN,urine creatinine if
nonsteroidal anti- myocardial infarction, lactation, vit K deficiency, peptic peripheral vessels; for prevention of heart patient is onlong term
inflammatory, antipyretic, prophylaxis of MI, ischemic ulcer decreases platelet attack/stroke, consult therapy
antiplatelet stroke, angina. aggregation. your doctor or -Blood Studies: CBC,
pharmacist for more Hct,Hgb, pro-time if
details and to discuss patient is onlong term
Arthritis Adult: 2.6-5.2 other possible therapy
g/day in divided doses treatments (such as -I&O ratio: decreasing
q4-q6h acetaminophen) for your outputmay indicate renal
pain/fever. failure
Pain/Fever Adult: 325- -Hepatotoxicity: dark
650 mgq4h prn, not urine,clay-colored stools,
4g/day yellowingof skin, sclera,
itching,abdominal pain,
fever anddiarrhea
-Visual changes:
blurring,halos; corneal,
retinal damageEdema in
feet, ankles and legs
Drug Study

Drug Indication Contraindication Drug Action Drug Interaction Nursing Responsibilities

Brand Name: Treatment of angina Reduces cardiac oxygen Some products that -Monitor blood pressure
nitroglycerin(Nitrostat pectoris Hypersensitivity to nitroglycerin demand by decreasing left may interact with this and heart rate on a regular
Sublingual and other components- closed- ventricular pressure and drug include: drugs basis.
Generic angle glaucoma-severe anemia- systemic vascular used to treat erectile -Instruct patient to take
Name: Nitro patch increased intracranial pressure- resistance; dilates coronary dysfunction-ED or medication while sitting
head trauma- uncorrected arteries and improves pulmonary down and to change
hypovolemia collateral flow to ischemic hypertension (such as positions slowly.
regions sildenafil, tadalafil), -Instruct patient to allow
certain drugs to treat tablets to dissolve under
Classification: Nitrates migraine headaches tongue, and not to chew or
(ergot alkaloids such swallow sublingual tablets.
as ergotamine), -Instruct patient to seek
riociguat. emergency help promptly if
tablet:0.2-0.6 mg SL q 5 chest pain is unresolved
minor maximum of 3doses after 15 minutes.
in 15 mins -Instruct patient not to
change brands without
consulting prescriber.
-Instruct patient to keep
tablets in original, air-tight
container.
-Advise patient to use
caution when engaging in
activities requiring mental
alertness.
-Advise patient to report
acute headache, rapid
heartbeat, unusual
restlessness or dizziness,
or blurring of vision
Drug Study

Nursing
Drug Indication Contraindication Drug Action Drug Interaction
Responsibilities
Brand Name: Management of cardiac Non selective beta- Some products that may -Obtain careful medical
arrhythmias, myocardial Peripheral arterial insufficiency; blocker of both cardiac interact with this drug history to rule out
Generic infarction, tachyar rythmias history of systemic insect sting and bronchial adreno include: alpha blockers (e.g., allergies, asthma, and
Name: Propranolol associated with digitalis reaction; patients prone to no receptors that prazosin), aluminum obstructive pulmonary
intoxication, anesthesia, allergenic bronchospasm (e.g. competes with hydroxide, anticholinergics disease
and thyrotoxicosis, Chronic bronchitis, epinephrine and ,chlorpromazine, drugs -Monitor apical pulse,
hypertropic subaortic emphysema); major surgery; norepinephrine for affecting liver enzymes that respiration, BP, and
stenosis, angina pectoris cerebrovascular disease, available beta-receptor remove propranolol from circulation to extremities
ROUTE due to coronary stroke; renal or hepatic disease; site your body (such as closely throughout period
&FREQUENCY:PO 1 tab Atherosclerosis, pheochromocytoma, cimetidine, St. John's wort, of dosage adjustment.
q12 pheochromocytoma, vasospastic angina; diabetes certain SSRI -Monitor I&O and daily
hereditary essential tremor; mellitus; patients prone antidepressants including weight as significant
also treatment of tohypoglycaemia; fluoxetine/paroxetine/fluvoxa indexes for detecting fluid
hypertension alone, but hyperthyroidism, thyrotoxicosis; mine, HIV protease retention and developing
generally with thiazide or surgery,MG; Wolff- inhibitors including ritonavir, heart failure.
other antihypertensive Parkinson_Whitesyndrome; rifamycins including -If patient complains of
older adults; pregnancy, rifabutin), other drugs to cold, painful, or tender
lactation treat high blood pressure feet and hands, examine
(e.g., clonidine, hydralazine, carefully for evidence of
methyldopa, reserpine), poor circulation.
epinephrine, fingolimod,
haloperidol, other heart
medications (e.g., digoxin,
disopyramide, propafenone,
quinidine), mefloquine,
rizatriptan, theophylline,
thioridazine, thyroid
hormones (e.g.,
levothyroxine), warfarin.
Drug Study

Drug Indication Contraindication Drug Action Drug Interaction Nursing Responsibilities

Brand Name: Zocor Adjunct to dietary therapy Inhibits an enzyme, 3- Simvastatin, like several other -Obtain a dietary history,
in the management of Contraindicated in: hydroxy-3- inhibitors of HMG-CoA reductase, especially with regard to fat
Generic primary hypersensitivity, cross- methylglutarylcoenzyme( is a substrate of CYP3A4. consumption.
Name: Simvastatin hypercholesterolemia and sensitivity among agents HMG-CoA) reductase, Simvastatin is metabolized by -Evaluate serum cholesterol
mixed dyslipidemias. may occur. Sepsis, acute which is responsible for CYP3A4 but has no CYP3A4 and triglyceride levels before
Reduction of hypotension, major catalysing an early step inhibitory activity; therefore it is not initiating, after 4-6 weeks
Classification: Lipid- lipids/cholesterol reduces surgery, trauma, severe in the synthesis of expected to affect the plasma therapy, and periodically there
lowering agent the risk of MI and stroke metabolic disturbances, cholesterol. Therapeutic concentrations of other drugs after.
sequelae and decreases endocrine or electrolyte Effects:>Lowering of total metabolized by CYP3A4. -Monitor liver function tests.
the need for by pass disorders, uncontrolled and LDL -Administer once daily in the
Dose:40 mg Route: procedures/angioplasty seizures and active liver cholesterol.>Increase Elevated plasma levels of HMG- evening. May be administered
PO disease. HDL and decrease VLDL CoA reductase inhibitory activity without regard to food.
Frequency: OD HS cholesterol and increases the risk of myopathy -Instruct patient to take
Use cautiously in: History triglycerides.>Slowing of and rhabdomyolysis, particularly medication as directed and not
of liver disease or the progression of with higher doses of simvastatin. to skip doses or double up on
significant alcohol coronary artery disease Concomitant use of drugs labeled missed doses
use/abuse. with resultant decrease as having a strong inhibitory effect
in MI/stroke and need for on CYP3A4 is contraindicated. If
myocardial treatment with it raconazole,
revascularization ketoconazole, posaconazole,
voriconazole, erythromycin,
clarithromycin or telithromycin is
unavoidable, therapy with
simvastatin must be suspended
during the course of treatment.
Drug Study

Nursing
Drug Indication Contraindication Drug Action Drug Interaction
Responsibilities
Brand Name: Calcibloc OD Treatment of high blood Inhibits Calcium ion from Calcibloc Capsule may -Monitor BP, heart rate,
pressure hypersensitivity to nifedipine or entering the “slow channels interact with the and I and O ratio closely
Generic any other calcium channel or select voltage-sensitive following drugs and when starting or
Name: Nifedipine blocker and adenosine areas of vascular smooth products: adjusting dosage. -
muscle and myocardium Aminophylline Monitor BP closely when
during depolarization, Neuromuscular-blocking used in conjunction with
producing a relaxation of agents other
Therapeutic category: coronary vascular smooth Theophylline antihypertensives.Use
Calcium channel blockers muscle and coronary orthostatic precautions
vasodilation; increases for inpatients; advise
Adults and Elderly: Initial: myocardial oxygen delivery outpatients about
10 mg 3 times/day as in patients with vasospatic orthostatic precautions.
capsules or 30 mg once angina -Monitor serum glucose
daily as sustained release. closely in diabetic
Usual dose: 10-30 mg 3 patients.
times/day as capsules. -Monitor for gingival
Maximum: 120-180 mg/day hyperplasia. Pregnancy
Risk Factor C- benefits of
use should outweigh
possible risks