C
oronary artery disease (CAD) is one
of the most common causes of (libido), divert blood from the iliac artery into
morbidity and mortality in developed the corpora cavernosa to achieve penile
and developing countries. Coronary artery tumescence and rigidity (erection) adequate
bypass graft (CABG) is the most common for penetration, then discharge sperm and
cardiac surgery around the world (1, 2, 3). prostatic and seminal vesicle fluid through the
One of the most important post-operative urethra (ejaculation), and experience a sense
complications is sexual dysfunction after on- of pleasure (orgasm) (5, 6).
pump or off-pump CABG (2). Etiology of ED, also known as impotence, is the
sexual dysfunction in these patients may be inability to achieve and/or maintain a penile
psychological or organic due to hormonal erection sufficient enough to participate in
changes. Normal sexual function has common satisfactory sexual activity. Frequency of ED
implications for emotional health and has significant relationship with age: 25% of
happiness, and sexual dysfunction may have 60-years-old men and 49% of 70-years-old
negative impacts on psychologic life resulting men have ED (2). At least 75% of patients
to stress, depression, loneliness and with heart disease experience one or more
decreased quality of social relationship (4). types of sexual dysfunction (7).
Sexual dysfunction may be classified into Androgenic hormones include
four main groups: loss of libido, erectile dihydroepiandrostenedione (DHEA), DHEA
Forouzannia et al
426 Iranian Journal of Reproductive Medicine Vol. 10. No. 5. pp: 425-428, September 2012
Sex hormones & sexual dysfunction after CABG
Iranian Journal of Reproductive Medicine Vol. 10. No. 5. pp: 425-428, September 2012 427
Forouzannia et al
428 Iranian Journal of Reproductive Medicine Vol. 10. No. 5. pp: 425-428, September 2012