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68 Bulletin of the Hospital for Joint Diseases 2013;71(1):68-78

Total Hip Arthroplasty Periprosthetic Femoral


Fractures
A Review of Classification and Current Treatment

Ran Schwarzkopf, M.D., M.Sc., Julius K. Oni, M.D., and Scott E. Marwin, M.D.

Abstract bone quality, and high fall risk), and broader indications
Periprosthetic fractures of the femur after total hip replace- for THA that allow younger, more active, and consequently
ment can present some unique challenges to the treating high-energy trauma prone patients to undergo the surgery.
reconstructive orthopedic surgeon. Treatment may differ Periprosthetic femur fractures are divided into intraopera-
depending on fracture location, bone condition, implant tive and postoperative fractures. Intraoperative fractures oc-
stability, patient characteristics, and surgeon experience. cur during the course of surgery and postoperative fractures,
It is imperative that adequate and sufficient mechanical the main focus of this review, usually occur within days to
fixation be achieved in the treatment of these patients. It is several years after the procedure. In a Swedish National
crucial that the treating orthopaedic surgeon have a clear Hip Arthroplasty registry study, the mean time from THA
and effective treatment plan to manage these complex cases. to fracture was 7.4 years for primary THA and 3.9 years for
The patient’s final outcome is dependent on fracture union, revision THA.1 Also, in a Mayo Clinic Total Joint Registry
implant stability, early functional recovery, and return to study, average time between primary THA and fracture was
pre-injury independence. This review presents an overview 8.1 years.2
of the current diagnostic and treatment approaches, with the Periprosthetic femoral fractures may present many
goal of providing a template for optimal decision-making challenges to the reconstructive orthopedic surgeon. Such
when dealing with these complex injuries. fractures can range from minor injuries, with minimal effect
on the patient’s outcome to being catastrophic and possibly

T
otal hip arthroplasty (THA) has been an extremely creating a non-reconstructable problem with a detrimental
effective procedure in relieving pain and dysfunction effect on the patient’s function. The economic impact and
for patients with hip arthritis of varying etiologies. disabilities associated with femoral periprosthetic fractures
However, after many decades of successful total hip re- can therefore be substantial. Thus, having a clear and effec-
placements, there has also been a substantial increase in the tive treatment plan to manage these injuries is crucial for
incidence of periprosthetic fractures following THA. This the treating physician.
increase in fracture prevalence is attributed to the substantial
increase in the number of primary and revision THAs being Prevalence
performed annually, the growing number of patients with a The prevalence of postoperative periprosthetic femoral
THA in place for more than 20 years, the aging population fractures ranges from 0.1% to 4% depending on the series
of THA patients (with increasing life expectancy, poorer reviewed, with higher rates after revision surgery.3-6 In a
Mayo Clinic retrospective study of total hip arthroplas-
ties performed between 1969 and 1990, the postoperative
Ran Schwarzkopf, M.D., M.Sc., Julius K. Oni, M.D., and Scott
femoral fracture prevalence after 19,657 primary THAs was
E. Marwin, M.D., are in the Department of Orthopaedic Surgery,
0.6%. The postoperative fracture prevalence for cemented
NYU Hospital for Joint Diseases, New York, New York.
Correspondence: Scott E. Marwin, M.D., Department of Ortho- primary arthroplasties was 0.6% of the 17,579 cemented
paedic Surgery, NYU Hospital for Joint Diseases, 301 East 17th primary arthroplasties and 0.4% of the 2,078 uncemented
Street, Suite 1402, New York, New York 10003; scott.marwin@ primary arthroplasties. In the revision arthroplasty group, the
nyumc.org. overall prevalence of postoperative periprosthetic fracture

Schwarzkopf R, Oni JK, Marwin, SE. Total hip arthroplasty periprosthetic femoral fractures: a review of classification and current treatment. Bull Hosp
Jt Dis. 2013;71(1):68-78.
Bulletin of the Hospital for Joint Diseases 2013;71(1):68-78 69

was higher at 2.4% of the 4,397 procedures performed, with and the condition of the acetabular component should be
2.8% of fractures occurring in the 3,265 cemented revision assessed as well, and if revision is warranted, it should be
cases and 1.5% of the 1,132 uncemented revision cases.2 addressed appropriately. Routine use of CT or MRI is usu-
ally not warranted.
Etiology
The main risk factor for sustaining a periprosthetic femur Classification
fracture is osteolysis associated with implant loosening.7 Several classification systems of periprosthetic fractures
In both the Mayo clinic and Swedish registry studies, 94% have been developed over the years.5,9-11 Most are descriptive
and 70% of patients respectively had a loose stem prior to and provide information about the location of the fracture
fracture.1,8 However, any pathologic process that weakens but have no significant value with regard to aiding the for-
bone may contribute to these fractures. Examples include os- mulation of a treatment strategy.
teoporosis and other conditions with pathologic bone such as The Vancouver classification system proposed by Duncan
rheumatoid arthritis, Paget’s disease, and polyneuropathies. and Masri is the most widely used system for classification of
Tumors, cortical defects, trauma, revision surgery, extruded total hip periprosthetic femoral fractures, although initially
cement, stress risers, and varus stem position are all also developed for THAs with cemented femoral components.5
significant risk factors for periprosthetic femoral fractures. The Vancouver classification takes into account the three
Age, sex, and body mass index have not been shown in any most important factors in management of these injuries: the
large study to be a significant risk factor. The most frequent site of the fracture, the stability of the femoral component,
mechanism for sustaining these fractures is a low energy and the quality of the surrounding femoral bone stock (Fig.
fall from sitting or standing, accounting for 75% of primary 1). In addition to being simple and reproducible, it is useful
THA and 56% of revision THA periprosthetic fractures.8 for devising a treatment strategy based on easily identifiable
characteristics. In particular, the Vancouver classification
Exam and Imaging helps the surgeon differentiate between a stable fracture and
A detailed assessment of the patient prior to treatment is es- an unstable fracture, which requires osteosynthesis, as well
sential in order to maximize the chances of a good outcome.
As previously stated, many periprosthetic femur fractures
occur from low-energy trauma such as a fall from standing
height. The treating physician must elicit from the patient’s
history any signs and symptoms that may suggest implant
loosening prior to the injury, such as thigh pain and start up
pain, usually reported as pain while rising from a chair or
at initiation of ambulation. A complete physical examina-
tion with an emphasis on the injured limb’s neurovascular
status should be carefully documented. Physical examination
may reveal inability to ambulate, tenderness to palpation
of the fracture site, and pain with range of motion of the
affected extremity. Preoperative planning should include
identification of previous surgical scars and soft tissue con-
dition, review of previous operative reports, especially for
identification of the currently implanted prosthesis and any
unusual intraoperative events, and appropriate workup if
septic loosening is suspected. Patients with fractures around
asymptomatic, well-fixed implants usually do not require an
infectious workup. High-quality standard anteroposterior
(AP) and lateral radiographs of the affected hip and femur
together with an AP radiograph of the pelvis should be ob-
tained. Images should be reviewed thoroughly to ascertain
the type of fracture and the stability of the implant.
Signs of a loose femoral stem include continuous lucency
at the cement-bone and cement-stem interfaces, as well as
cement mantle fractures prior to incurring the periprosthetic
fracture. Post-injury cement mantle fracture is not a sign
Figure 1 The Vancouver classification of periprosthetic femur
of stem loosening by itself. Failure to identify an unstable fractures around total hip arthroplasty. The classification is based
implant is likely to lead to treatment failure if osteosynthesis on the location of the fracture, stability of the femoral implant,
rather than revision arthroplasty is performed. The stability and quality of the surrounding bone stock.
70 Bulletin of the Hospital for Joint Diseases 2013;71(1):68-78

characteristics like age and medical co-morbidities, and


surgeon experience.
Historically, non-operative treatment was the mainstay
for periprosthetic femoral fractures.13 With advances in
surgical techniques and instrumentation, the balance has
shifted in favor of surgical management, thus avoiding
the recognized complications associated with prolonged
recumbency such as thromboembolism, pneumonia, pres-
sure ulceration and knee joint contractures. Nevertheless,
non-operative treatment is still recommended for a subset
of patients with otherwise operative fractures who are un-
able to tolerate a prolonged surgical procedure for medical
reasons, especially if they are non-ambulatory and have low
levels of physical function. There is no consensus regarding
the use of skeletal or cutaneous traction preoperatively for
periprosthetic femur fractures. The goals of surgery should
be fracture union, prosthetic stability, anatomical alignment,
rotation, and length, as well as return to pre-injury function.
In cases of severe osteopenia, osteosynthesis with relative
stability techniques, such as bridging of comminuted seg-
ments, should be employed. In cases where revision total hip
arthroplasty is being contemplated as the treatment option,
the possibility of infection should be considered and ruled
out. Unfortunately, laboratory studies, such as white blood
cell count, erythrocyte sedimentation rate, and C-reactive
Figure 2 Radiograph of a Vancouver type ALT periprosthetic protein, are not as useful in the presence of a periprosthetic
femur fracture. The lesser trochanter is fractured along with the
medial cortex.
fracture compared to failed total hip arthroplasty without a
fracture.14 A hip aspiration culture may, however, be helpful
as a stable implant from an unstable implant, which requires when septic loosening prior to fracture is suspected.
revision. The Vancouver classification has been validated in Many different treatment options have been described
several studies.12 in the literature, and no single treatment has been shown
to be the gold standard. The following is a presentation of
Vancouver Classification common treatment options for each fracture type.
Type A fractures include those involving the lesser tro-
chanter (ALT) (Fig. 2) or the greater trochanter (AGT). These Vancouver Type ALT
fractures are most commonly associated with osteopenia of Type ALT fractures are rare, and usually non-operative
the proximal femur. treatment is required, unless the fracture compromises the
Type B fractures occur around or just distal to the femoral stability of the implant by involving a large portion of the
stem. Type B fractures are further divided into subtypes: calcar region with loss of the medial buttress (Fig. 3). In this
B1-adjacent to a well-fixed stem, B2-adjacent to a loose case, treatment may include cerclage wiring and revision if
stem but with adequate bone stock, and B3-adjacent to the implant is deemed unstable.
a loose stem and associated with marked osteopenia and
loss of bone stock. This sub-classification is critical to the Vancouver Type AGT
decision making process of the treating physician because Type AGT fractures are usually stable, due to the composite
a fracture accompanied by a loose implant requires revision tendons of the vasti and glutei muscles, and treatment for
arthroplasty compared to osteosynthesis for fractures associ- non-displaced fractures is non-operative, with protected
ated with a stable implant. weight bearing for 6 to 12 weeks and avoidance of hip abduc-
Type C fractures are far distal to the femoral stem, such tion until fracture union is achieved.15 Displaced fractures
that their treatment is independent of the total hip arthro- may require fixation, either with a hook cable plate con-
plasty. struct or cerclage fixation, in order to restore the functional
leverage arm of the glutei muscles. Often, osteolysis of the
Treatment proximal femur is associated with these type A fractures.
Treatment of total hip periprosthetic femoral fractures is In these cases, operative treatment is warranted and should
dependent on a few fracture characteristics such as fracture include bone grafting of the osteolytic lesion, trochanteric
location, femoral bone stock, implant stability, patient’s fixation, and acetabular liner revision to address the underly-
Bulletin of the Hospital for Joint Diseases 2013;71(1):68-78 71

Type A

AGT ALT

Displaced Minimal Stable Displaced


or no medial
displacement cortex

No Osteolysis Osteolysis No No Cerclage


Osteolysis Osteolysis Treatment wire

Fixation with Fixation with Protected


cerclage wire or cerclage wire or weightbearing
trochanteric claw trochanteric claw
plate system plate system with
bone grafting
Figure 3 Treatment algorithm for Vancouver type A periprosthetic femur fractures.

ing cause of osteolysis. In a study of with mean follow-up of the fracture by at least two femur widths. Biomechanical
of 11years, Hsieh and associates16 reported an incidence of studies by Larson and colleagues showed that perforation
greater trochanteric periprosthetic fractures as 2.6%. They of the femur led to a 44% reduction in the original strength
also reported that these fractures all occurred in the pres- of the femur and osteosynthesis with a plate that bridged
ence of an osteolytic lesion 4 to 11 years postoperatively. the fracture area by two femur widths re-established the
Fifteen of 17 patients treated non-operatively for minimally stability of the bone to 84% of its original strength.17 Intra-
displaced fractures healed clinically and radiographically operative stability testing can be done without an arthrotomy,
by 6 to 8 weeks, but all fractures eventually healed without if the distal stem is exposed in the fracture site. However, if
further displacement, as did all four patients that underwent there is any doubt about the implant stability, intraoperative
operative treatment. Pritchett and coworkers15 showed that stability testing utilizing hip arthrotomy and dislocation is
trochanteric fractures that have migrated less than 2 cm could recommended.
be treated successfully non-operatively, and internal fixa-
tion should be considered in cases of displacement greater Vancouver Type B1
than 2.5 cm or when trochanteric nonunion results in pain, Controversy still exists regarding the preferred fracture
instability, or abduction weakness. fixation technique for type B1 fractures, given the high
stress location of these fractures and the femoral implant.
Vancouver Type B In general, type B1 fractures should be treated with open
Type B fractures represent approximately 80% of all cases. reduction and internal fixation with or without cortical
Sub-classification and treatment options depend on the mor- strut allograft based on the bone quality observed intra-
phology of the fracture, the stability of the femoral compo- operatively (Fig. 5). There are several options for internal
nent, and the quality of the proximal femoral bone (Fig. 4). fixation, most of which have shown good to excellent
At the time of surgery, the surgeon should be familiar outcomes. Historically, these fractures were treated with
and feel comfortable with the extensile approaches to the stainless steel cerclage wires and open reduction and in-
hip and femur. The surgeon should try to minimize soft tis- ternal fixation with rigid dynamic compression plates.9,18-20
sue trauma when feasible and preserve blood supply to the However, many studies have reported that cerclage wir-
fracture fragments by limiting surgical dissection. When ing alone has a high failure rate, and proximal unicortical
using plate fixation, it is important to bypass the distal limit screws in dynamic compression plates, while more stable
72 Bulletin of the Hospital for Joint Diseases 2013;71(1):68-78

Type B

Minimal Displaced fracture


displacement and
stable implant

May treat Stable impant B1 Loose


with protected Implant
weightbearing

Surgical Poor bone Good bone


Fixation with stock B3 stock B2
osteosynthesis
and strut graft
Young Elderly Long stem
patient patient revision

Revision with a long Proximal femoral


stem implant and replacement
bone graft
Consider allograft
prosthesis composite

Figure 4 Treatment algorithm for Vancouver type B periprosthetic femur fractures.

than cerclage wiring alone, are also inadequate.21-26 Also, in isolation or may be augmented with cortical allograft
when standard plates and screws are used, they tend to struts, and they provide the surgeon with many options for
violate the cement mantle. Additionally, if a canal-filling securing the plate to the femur without interfering with the
uncemented stem is present, it may be difficult to insert femoral implant or the cement mantle.
screws around the implant, thereby compromising fixa- Some studies have shown that a trochanteric plate with
tion strength. Therefore, as an alternative, plates that can proximal unicortical and distal bicortical screws or a plate
accommodate cables and screws have been designed and with proximal unicortical screws combined with cerclage
are available from most implant manufacturers. The first of wires and distal bicortical screws are a sufficiently strong
these cable-plate constructs was the Ogden plate, (Zimmer, mechanical construct.21,28 Tadross and coworkers reported
Warsaw, IN) introduced in 1976, and best described as a on seven periprosthetic femoral fractures treated with cable
metallic bone side plate that was secured to the proximal plates, of which three achieved union, two failed to unite,
fragment by Parham bands and to the distal fragment by and two malunited in varus.29 In the Swedish Registry study,
screws.27 The relative ease, minimal morbidity, and stabil- Lindahl and associates found the revision rate after internal
ity of this technique made it popular, but its disadvantages fixation of Vancouver B1 periprosthetic fractures to be 59%.
included the potential for stress risers as a result of the They reported that the strongest negative prognostic factor
transcortical screws, fractures below the plate, prosthetic was the use of a single non-locked plate for fixation.1
loosening, and nonunion.27 Therefore, many modifications The use of cortical strut grafts is, therefore, a good alter-
on the same treatment modality have been developed since native or adjunct fixation method. Strut grafts, in the case of
the introduction of this technique, as evident in the mod- stable implants (type B1), may be used as the only means
ern day cable plating systems. These plates can be used of stabilization with either a single strut or as a double strut
Bulletin of the Hospital for Joint Diseases 2013;71(1):68-78 73

Figure 5 A, A radiograph of a
Vancouver type B1 femur frac-
ture, with a fracture at the level
of the tip of the stem with a stable
implant. B, This fracture was
treated with open reduction and
internal fixation with a locked
plate construct using unicortical
A B screws proximally and bicortical
screws distally.

complex in a 90° or 180° to each other or in combination unions, but all had less than 10º of malalignment, and the
with osteosynthesis (Fig. 6). Strut grafts have an advantage investigators suggested that cortical strut grafts should
of being a biological and osteoconductive osteosynthesis be routinely used in the treatment of these periprosthetic
technique, providing reduced stress shielding due to similar fractures. They also suggested that combined plating
modulus of elasticity as the native bone, and augmenting with proximal cable fixation augmented with an anterior
host bone stock and strength after union.12,21,30-32 Placing or medial strut graft may provide better fixation than an
two strut grafts with three fixation points above and below allograft strut alone.30 Biomechanical studies by Dennis
the fracture have been shown to yield good outcomes.33,34 and associates demonstrated that plates with proximal uni-
Emerson and colleagues reported a 96.6% incorporation rate cortical screws or unicortical screws and cerclage, as well
in 63 cases were strut grafts were used, with a high rate of as distal bicortical screws, achieved a significantly more
fracture healing.35 stable osteosynthesis than plates with cerclage alone, plates
In a multicenter study of 40 type B1 periprosthetic with just proximal cerclage and distal bicortical screws
fractures, Haddad and coworkers treated 19 patients with (Ogden construct) or two strut grafts (SGs) with cerclage
cortical strut onlay grafts alone, while 21 patients were alone.22 The disadvantages of strut grafts are their high
managed by a plate and one or two cortical struts. Union cost, limited availability, increased danger of infection, and
occurred in 98% of the fractures. There were four mal- potential for transmitting disease. In addition, remodeling
occurs subsequent to the initial incorporation of the strut
graft, and this leads, in turn, to biomechanical weakness
during the first 4 to 6 months following grafting.
The recent introduction of locking plates has provided
another excellent alternative for fixation of these fractures.
These plates use screws that lock into the plate allowing
multiple points of unicortical or bicortical fixation. These
plates have the advantage of increased axial and angular
stability, indirect fracture reduction, less soft tissue dissec-
tion, preservation of periosteal blood supply, strong fixation
in bone of poor quality, and less damage to cement mantle
or stable implant due to possibility of multiple proximal
unicortical fixation points. In a biomechanical study com-
paring the locking plate and Ogden construct, Fulkerson
and coworkers reported locking plates to be stiffer than the
Ogden construct in pre- and post-cyclic axial loading and
Figure 6 Clinical photograph of a periprosthetic femur fracture torsion.36 The investigators concluded that locked plating is
with a fixation construct utilizing a strut allograft and plate fixation not mechanically superior compared to conventional plating
with locked screws and cerclage wires. although it does offer the advantages of minimally invasive
74 Bulletin of the Hospital for Joint Diseases 2013;71(1):68-78

fixation techniques. Another biomechanical study by Choi Cementless implants with distal fixation have an advan-
and colleagues compared the strength of three constructs tage of bypassing the fracture site and having their point of
for treating comminuted type B1 fractures and found that a fixation outside the area of injury. This allows the fracture to
double anterior and lateral locked plates construct is stronger be fixed around the stem, with cables, struts, and plates (Fig.
than the lateral plate and anterior strut allograft construct, 7). Fracture fragments should be separated to enable canal
which in turn was stronger than a single lateral locking plate debridement and reaming to provide adequate implant fit in
construct.37 A few studies have shown excellent outcomes patients treated with long stem bypass fixation. If rotational
with use of locking plates either in isolation or augmented stability, soft tissue tensioning, or restoration of limb length
with cerclage wires and strut allografts.38-40 In summary, it are concerns, then a fluted modular noncemented stem may
would, therefore, seem logical to combine a plate, locked or be considered. Strut allograft may be needed for preliminary
non-locked, with distal bicortical screw fixation and proxi- stability of the construct in select cases, such as that of a
mal unicortical screw fixation supplemented with an onlay rotationally unstable transverse fracture.
cortical strut allograft fixed by cables. Locking screws may, Sledge and associates proposed an algorithm for treatment
however, be preferred in patients with poor bone quality. of Vancouver type B2 fractures.41 They recommended that
fracture fragments should first be reduced to reconstitute the
Vancouver Type B2 proximal tube of the femur and held together with doubled
Revision arthroplasty is the treatment of choice when the 18 gauge cerclage wires. Once the new stem is in position,
prosthesis is loose or fractured. Duncan and Masri reported it is then stabilized by the addition of the allograft struts as
that 82% of type B fractures occurred in the presence of a needed.41
loose implant.5 Bethea and coworkers reported that 75% In cases where there is significant proximal bone de-
of all postoperative femoral fractures are related to loose ficiency in revision total hip arthroplasty, distally fixed
implants.9 Therefore, a majority of all periprosthetic femur porous-coated stems are used to gain intramedullary fixa-
fractures are either type B2 or B3. When considering type B2 tion for complex periprosthetic fractures. MacDonald and
fractures, some questions that need to be addressed include colleagues reported on 14 cases of postoperative fracture
how long the femoral prosthesis should be, cemented versus treated with extensively coated cementless stems, and all
non cemented stem, cerclage wires or plates for fracture 14 fractures healed with no deformity at an average of 8.4
reduction, and if strut allograft will be used to augment years status post-surgery.42
the fixation. The most commonly recommended fixation Tower and Beals studied 102 revisions for periprosthetic
for type B2 fractures is revision with a long femoral stem, fracture of the femur from 30 surgeons and reported a 62%
effectively bypassing the fracture by a minimal distance rate of complications for cemented revisions, with 38%
of two femoral diameters with at least 5 cm of diaphyseal loosening and 24% of other complications, such as infec-
fit.2,5,17 The disadvantage of a cemented implant is the pos- tion, dislocation, or trochanteric nonunion.43 Cementless
sible excursion of the cement into the fracture site, which revisions were reported to have a 34% complication rate,
can impede fracture union and healing. with 18% rate of subsidence (some of which stabilized), 7%

Figure 7 A, Radiograph of a
Vancouver type B2 periprosthetic
femur fracture, with a fracture
at the level of the stem with an
unstable implant. B, Cerclage
wires were used to reduce the
fracture and revision arthroplasty
A B was performed with a long stem
to gain distal fixation.
Bulletin of the Hospital for Joint Diseases 2013;71(1):68-78 75

Figure 8 A, Radiograph of a
Vancouver type B3 periprosthetic
femur fracture. The fracture is at
the level of the stem, with a loose
implant, and poor bone quality.
B, In this elderly, low demand
A B patient, a proximal femoral re-
placement was used.

rate of loosening, and 9% dislocation, trochanteric nonunion, fracture union. In summary, type B2 fractures are complex
or infection.43 Given the higher rates of complication with procedures needing both stabilization of the fracture while
cemented techniques, changing to a cemented stem is gener- also revising the femoral component.
ally only recommended for older patients with osteoporotic
bones or patients with irradiated bone, in whom cementless Vancouver Type B3
fixation would be more challenging. When the patient is frail Revision arthroplasty is the treatment of choice for type
and elderly and could benefit from a quicker procedure, the B3 fracture patterns. There are no major series of type B3
cement-in-cement technique may be considered. The tech- fractures in the literature. However, these are challenging
nique is indicated for non-comminuted fractures with well- cases with a high rate of complications. It is essential that
fixed, good-quality cement mantles. The approach is faster the implant obtain adequate distal fixation to provide axial
and technically less demanding, resulting in theoretically less and rotational stability, as the proximal bone does not usu-
blood loss and lower risk of iatrogenic bone fragmentation ally give sufficient support. In young patients, restoration
during cement removal.44 The use of the cement-in-cement of bone stock is a priority; therefore, an allograft-prosthesis
technique for femoral component revision has excellent composite is an attractive option.47 Wong and associates
clinical outcomes and long-term results, with survivorship reported their experience with 15 type B3 fractures treated
of 98% to 100% at 5 to 15 years.44 with an allograft-prosthesis composite, with a rate of heal-
Another alternative for treating type B2 fractures is the ing of 93.3%.32
use of cementless revision stems with distal interlocking In older and low functional demand patients, a proximal
screws. Mertl and coworkers retrospectively reviewed the femoral replacement or “megaprosthesis” may be used (Fig.
use of interlocking stems in 725 patients with an average 8). In contrast to an allograft composite, this option allows
follow up of 4.5 years.45 The main advantages of these immediate weightbearing after surgery, which is an essential
interlocking stems are initial axial and rotational stability component of care for this population group.21 Because of
and consistent bony in-growth due to the hydroxyapatite soft tissue deficiency, a constrained acetabular liner may be
coating.45 In a study of 118 type B2 and type B3 fractures, needed to prevent instability. There are only scarce reports
different uncemented stems (a proximally porous coated of treatment outcomes for Vancouver type B3 periprosthetic
uncemented stem, an extensively porous-coated stem, or fractures. Proximal femoral replacement for these fractures
an allograft prosthetic composite/tumor prosthesis) were has been shown to be effective with a 64% survivorship at
implanted in different patients, Springer and coworkers 12 years.48
found that the uncemented extensively porous coated im- Impaction grafting and cemented stem fixation should
plants had the most stable fixation and were not associated be considered for select cases of femoral periprosthetic
with any nonunions.6 In another study, Ko and colleagues fractures, with significant comminution at or below the level
followed 12 patients with type B2 fractures treated with the of the femoral isthmus that can prevent achieving axial and
Wagner revision stem for an average of 58.5 months.46 All rotational stability of a traditional long cementless porous-
12 patients were found to have stable prostheses and solid coated femoral stems. The advantages of long-stem cement-
76 Bulletin of the Hospital for Joint Diseases 2013;71(1):68-78

Type C with type B2 and B3 fractures treated with cementless, ta-


pered, fluted and distally fixed stems, Mulay and colleagues
reported that 91% of fractures healed although there were
five dislocations and two nonunions.51
Adequate Poor
Vancouver Type C
bone stock bone stock Surgical fixation is the treatment of choice for this pattern
of fractures (Fig. 9). There are numerous types of fixation
devices available to address these fractures including locking
Plate Plate and plates, screw and cable hybrid plates, and intramedullary
devices. Our recommended implant of choice is a hybrid
fixation strut graft plate with unicortical screws and cable fixation proximally
fixation around the femoral stem and bicortical screws distal to the
femoral stem (Fig. 10). Occasionally, a strut allograft may
Figure 9 Treatment algorithm for Vancouver type C periprosthetic be used to provide a more stable construct. Care should be
femur fractures. taken to avoid leaving a segment of weak, unprotected bone,
between the intramedullary implant and the proximal end
ed femoral fixation augmented with impaction bone grafting of the plate. Adequate overlap should be achieved to avoid
include intramedullary fixation of the implant, presence of such stress risers that may lead to a recurrent fracture.
osteoconductive agents at the fracture site, immediate stabil- The main concern with intramedullary nail fixation relates
ity provided by the use of cement, and potentially reliable to the possibility of creating a stress riser between the tip of
long-term prosthetic fixation and restoration of bone stock.49 the nail and the femoral component. Fractures close to the
An alternative to impaction grafting is the use of modular tip of the stem may be treated with the same techniques as
long-stemmed fluted cementless femoral components, as type B1 fractures.
these stems do not require as much femoral diaphysis for
fixation compared with the traditionally fully porous-coated Outcomes
implants and they provide three-point fixation to anchor Outcomes of periprosthetic femur fractures have been
the prosthesis distally. Berry and coworkers reported the reported on by many investigators. Young and coworkers
outcomes of seven patients with type B3 fractures treated compared 232 periprosthetic femur fracture patients with
with fluted, tapered stems and followed for an average of matched patients who underwent total hip revision; they
2 years.50 All fractures healed, and all implants were stable found a higher 6 month mortality rate (7.3% vs. 0.9%, p
as of the most recent follow-up. In a study of 24 patients < 0.001) and higher likelihood of re-revision (7.3% vs.

Figure 10 A, Radiograph of a
Vancouver type C periprosthetic
femur fracture, occurring distal
to the stem of the total hip arthro-
plasty. This patient also had an
ipsilateral total knee arthroplasty.
Both implants were determined to
be stable. B, A locked plate con-
struct was used with unicortical
screws proximally and bicortical
screws distally, with retention of
A B both the total hip and total knee
prostheses.
Bulletin of the Hospital for Joint Diseases 2013;71(1):68-78 77

2.6%, p = 0.06) in the periprosthetic fracture patients. The femur after total hip arthroplasty. Arch Orthop Trauma Surg.
most common indications for re-revision were dislocation 1987;106(6):353-7.
and re-fracture.52 Bhattacharyya and associates reported a 4. Berry DJ. Epidemiology: hip and knee. Orthop Clin North
1 year mortality rate of 11% in patients treated operatively Am. 1999 Apr;30(2):183-90.
5. Duncan CP, Masri BA. Fractures of the femur after hip re-
for periprosthetic femur fractures compared with 2.9% in
placement. Instr Course Lect. 1995;44:293-304.
patients who underwent primary joint replacement, and 16%
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Summary thetic femoral fractures classification and demographics
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National Hip Arthroplasty Register. J Arthroplasty. 2005
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Oct;20(7):857-65.
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57.
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Disclosure Statement
16. Hsieh PH, Chang YH, Lee PC, Shih CH. Periprosthetic frac-
None of the authors have a financial or proprietary interest
tures of the greater trochanter through osteolytic cysts with
in the subject matter or materials discussed, including, but
uncemented MicroStructured Omnifit prosthesis: retrospec-
not limited to, employment, consultancies, stock ownership,
tive analyses pf 23 fractures in 887 hips after 5-14 years. Acta
honoraria, and paid expert testimony.
Orthop. 2005 Aug;76(4):538-43.
17. Larson JE, Chao EY, Fitzgerald RH. Bypassing femoral corti-
Acknowledgments cal defects with cemented intramedullary stems. J Orthop Res.
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Nirmal Tejwani for providing some of the images used in 18. Partridge AJ, Evans PE. The treatment of fractions of the
this manuscript. shaft of the femur using nylon cerclage. J Bone Joint Surg
Br. 1982;64(2):210-4.
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