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EMULSI
EMULSI
EMULSI
EMULSI
Terminologies  Two immiscible liquid:  Continues phase (external phase, medium)  Disperse phase (internal
Terminologies
 Two immiscible liquid:
 Continues phase (external phase, medium)
 Disperse phase (internal phase, droplet)
 Sistem multifase di mana salah satu fase (fase kontinyu)
mengandung droplet fase yang lain (fase terdispersi).
 Biasanya merupakan sistem dua fase di mana fase kontinyu
memiliki volume relatif lebih besar daripada fase terdispersi.
 dispersi koloidal dua cairan yang tidak bersatu ( immiscible
liquid),
 globul terdispersi di dalam fasa pendispersi
dispersi koloidal dua cairan yang tidak bersatu ( immiscible liquid),  globul terdispersi di dalam fasa
dispersi koloidal dua cairan yang tidak bersatu ( immiscible liquid),  globul terdispersi di dalam fasa
Tujuan & Keuntungan bentuk emulsi  Memperbaiki penampilan sediaan karena merupakan campuran yang ‘homogen’
Tujuan & Keuntungan bentuk emulsi
 Memperbaiki penampilan sediaan karena
merupakan campuran yang ‘homogen’ secara
visual  ESTETIKA
 Meningkatkan stabilitas obat yang lebih
mudah terhidrolisa dalam air.
 Penetrasi dan absorpsi dapat dikontrol
 Can be used to prolong the release of the
drug - sustained action/kerja panjang
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Keuntungan bentuk emulsi Pemakaian oral (biasanya tipe M/A). Tipe M/A bertujuan untuk:  Menutupi rasa
Keuntungan bentuk emulsi
Pemakaian oral (biasanya tipe M/A). Tipe M/A
bertujuan untuk:
 Menutupi rasa dan bau minyak yang tidak enak
 Lebih mudah diabsorpsi dan dicerna karena ukuran
minyak diperkecil.
 Ketersediaan hayati lebih baik karena sudah dalam
bentuk terlarut.
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Disadvantages Highly unstable 1. Susceptible to temperature and pH changes. 2. Microbial growth and subsequent
Disadvantages
Highly unstable
1.
Susceptible to temperature and pH changes.
2.
Microbial growth and subsequent spoilage is common in
3.
emulsions prepared by using natural emulgents.
Size of globules is of great concern in parenteral
4.
administration
PH 201.42
5
Komposisi dasar Td 3 komponen / Campuran Terner Fase lipid Fase air Emulsifying agent
Komposisi dasar
Td 3 komponen / Campuran Terner
Fase lipid
Fase air
Emulsifying agent
Aturan Gibs :
Aturan Gibs :

F C - P 2

F = jumlah derajat kebebasan sistem (suhu, tekanan, konsentrasi) C = jumlah komponen P =
F = jumlah derajat kebebasan sistem (suhu, tekanan,
konsentrasi)
C = jumlah komponen
P = jumlah fase yang ada
P  2 F = jumlah derajat kebebasan sistem (suhu, tekanan, konsentrasi) C = jumlah komponen
P  2 F = jumlah derajat kebebasan sistem (suhu, tekanan, konsentrasi) C = jumlah komponen
SISTEM TIGA KOMPONEN Pada system dengan 3 komponen derajat bebas tertinggi adalah F = 3
SISTEM TIGA KOMPONEN
Pada
system
dengan
3
komponen
derajat
bebas
tertinggi adalah F = 3 – 1 + 2 = 4
dengan
menganggap
sistem
terkondensasi
yaitu
uap
diabaikan,
dan
sistem
dikerjakan
pada
suhu
tetap
maka tinggal konsentrasi yang
divariasi.
Sistem
dapat
digambarkan
sebagai
diagram
terner.
Contohnya
adalah
campuran
air-emulgator-
minyak.
7
KAIDAH DIAGRAM SEGITIGA  Masing – masing sudut menunjukkan 100% berat satu komponen  Ketiga
KAIDAH DIAGRAM SEGITIGA
 Masing – masing sudut
menunjukkan 100%
berat satu komponen
 Ketiga
garis
yang
menghubungkan
titik
titik
sudut
menunjukkan
campuran
dua
komponen
dari
kemungkinan
kombinasi A, B, dan C
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Contoh Perhitungan  Apabila dibuat campuran dengan komposisi 5 gram zat A (Air), 15 gram
Contoh Perhitungan
 Apabila dibuat campuran dengan komposisi 5 gram zat A (Air), 15
gram zat B (Parafin) dan 100 gram zat C (Brij) , maka berapakah
persentase berat masing-masing bahan? Dimanakah letaknya dalam
diagram segitiga? Apakah terbentuk Emulsi yang baik?

% zat A

5

(5

 

15 100)

x100%

4,17%

% zat B

15

(5

15 100)

x100%

12,5%

% zat C

100

(5

15 100)

x100%

83,33%

10
10
A = 4,17% B = 12,5% C = 83,33% Titik F A:B = 4,17 :
A = 4,17% B = 12,5% C = 83,33%
A = 4,17%
B = 12,5%
C = 83,33%
Titik F
Titik F

A:B = 4,17 : 12,5

= 1 : 3
= 1 : 3
Titik E
Titik E

A:B = 16,67 : 50

= 1 : 3
= 1 : 3
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Classification
Classification

Emulsions

Classification Emulsions Macro emulsions Mini emulsions Molecular emulsions Primary emulsions / Simple emulsions
Macro emulsions Mini emulsions Molecular emulsions Primary emulsions / Simple emulsions Secondary emulsions /
Macro emulsions
Mini emulsions
Molecular emulsions
Primary
emulsions /
Simple emulsions
Secondary emulsions /
Multiple emulsions
PIT emulsions
Micro emulsions
O/W/O
Micellar emulsions
O/W
Nano emulsions
W/O/W
W/O
PH 201.42
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Microscopic view of emulsions PH 201.42 13
Microscopic view of emulsions
PH 201.42
13
Droplet size and the appearance of emulsions M I N I E M U L

Droplet size and the appearance of

emulsions
emulsions

M

I

N

I

E

M

U

L

S

I

O

N

S

and the appearance of emulsions M I N I E M U L S I O
and the appearance of emulsions M I N I E M U L S I O
and the appearance of emulsions M I N I E M U L S I O

Macroemulsion

Microemulsions

PH 201.42 14
PH 201.42
14
Thermodynamic stability of different types of emulsions
Thermodynamic stability of different types of emulsions
Thermodynamic stability of different types of emulsions
Thermodynamic stability of different types of emulsions PH 201.42 15
Thermodynamic stability of different types of emulsions PH 201.42 15
PH 201.42 15
PH 201.42
15
Types of emulsion  Oil-in-Water (O/W):  oil droplets are dispersed throughout the aqueous phase.
Types of emulsion
 Oil-in-Water (O/W):
 oil droplets are dispersed throughout the aqueous
phase.
 Water-in-Oil (W/O):
 the water is dispersed throughout the oil phase.
dispersed throughout the aqueous phase.  Water-in-Oil (W/O):  the water is dispersed throughout the oil
dispersed throughout the aqueous phase.  Water-in-Oil (W/O):  the water is dispersed throughout the oil
dispersed throughout the aqueous phase.  Water-in-Oil (W/O):  the water is dispersed throughout the oil
Types of emulsion  Multiple emulsion: Multiple emulsions are primarily used for formulating sustained release
Types of emulsion
 Multiple emulsion: Multiple emulsions are primarily
used for formulating sustained release dosage forms.
 water-in-oil-in-water (w/o/w) emulsion  A small water droplet is enclosed in larger oil droplet
 water-in-oil-in-water (w/o/w) emulsion
 A small water droplet is enclosed in larger oil droplet which is itself
dispersed in water
 oil-in-water-in-oil (o/w/o) emulsion
 A small oil droplet is enclosed in water droplet which is itself dispersed
in oil phase
(o/w/o) emulsion  A small oil droplet is enclosed in water droplet which is itself dispersed
(o/w/o) emulsion  A small oil droplet is enclosed in water droplet which is itself dispersed
(o/w/o) emulsion  A small oil droplet is enclosed in water droplet which is itself dispersed

Differences between O/W and W/O emulsions

Oil in water emulsion (O/w)

Water in oil emulsion (w/o)

Water is the dispersion medium

Oil is the dispersion medium

Oil is the dispersed phase

Water is the dispersed phase

Non greasy and easily removable from the

Greasy and not water washable

skin surface

Used externally to provide cooling effect e.g.

Used externally to prevent evaporation of

vanishing cream

moisture from the surface of skin e.g. Cold cream

Water soluble drugs are more quickly

Oil soluble drugs are more quickly released from

released from o/w emulsions

w/o emulsions

Preferred for formulations meant for internal use as bitter taste of oils can be masked.

Preferred for formulations meant for external use like creams.

Give a positive conductivity test as water is

Do not give a positive conductivity test as oil is

the external phase which is a good conductor of electricity.

the external phase which is a poor conductor of electricity.

PH 201.42

19
19
Identification tests for emulsions Since emulsion (o/w or w/o) looks the same in appearance with
Identification tests for emulsions
Since emulsion (o/w or w/o) looks the same in appearance
with naked eyes, therefore certain tests have been
developed to differentiate between them.
They are
1. Dilution test (emulsion can be diluted only with external
phase)
2. Dye test (using water or oil soluble dyes)
3. Electrical conductivity test (o/w emulsions conduct
electric current)
PH 201.43
20
Identification tests for emulsions…… Fluorescence test (some oils fluoresce under UV light) 4. 5. Cobalt
Identification tests for emulsions……
Fluorescence test (some oils fluoresce under UV light)
4.
5.
Cobalt chloride paper test (CoCl 2 blue paper turns pink
when hydrated)
Depending on the direction of creaming
6.
At least two tests should be done to reach a conclusive
decision about the identity of the emulsion.
PH 201.43
21
1. Dilution test Few drops of water Water distribute uniformly O/W emulsion Water separate out

1. Dilution test

1. Dilution test Few drops of water Water distribute uniformly O/W emulsion Water separate out as
1. Dilution test Few drops of water Water distribute uniformly O/W emulsion Water separate out as
Few drops of water
Few drops
of water
1. Dilution test Few drops of water Water distribute uniformly O/W emulsion Water separate out as
1. Dilution test Few drops of water Water distribute uniformly O/W emulsion Water separate out as

Water distribute

uniformly

Dilution test Few drops of water Water distribute uniformly O/W emulsion Water separate out as layer

O/W emulsionDilution test Few drops of water Water distribute uniformly Water separate out as layer Few drops

Few drops of water Water distribute uniformly O/W emulsion Water separate out as layer Few drops

Water separateFew drops of water Water distribute uniformly O/W emulsion out as layer Few drops of emulsion

out as layer

Few drops

of emulsion

emulsion Water separate out as layer Few drops of emulsion W/O emulsion Based on the solubility

W/O emulsionemulsion Water separate out as layer Few drops of emulsion Based on the solubility of external

Based on the solubility of external phase of emulsion.

- o/w emulsion can be diluted with water.

- w/o emulsion can be diluted with oil.

diluted with water. - w/o emulsion can be diluted with oil. Dilution Test for oil in

Dilution Test for oil in water

can be diluted with oil. Dilution Test for oil in water Dilution test for water in

Dilution test for water in oil emulsion

emulsion

PH 201.43 22
PH 201.43
22
 Emulsion is mixed with a water soluble dye such as amaranth and observed under
 Emulsion is mixed with a
water soluble dye such as
amaranth and observed under
the microscope, if the
continuous/external phase
appears red and
continuous/external phase
colorless, then it is w/o type.
 Similarly if an oil soluble dye
such as Scarlet red or Sudan
III is added to an emulsion and
the continuous phase appears
red, then it w/o emulsion. PH 201.43
2. Dye Solubility Test
2. Dye Solubility Test

water soluble dye amaranth

23
23
3. Electrical Conductivity Test  Based on the basic principle that water is a good
3. Electrical Conductivity Test
 Based on the basic principle that water is a good
conductor of electricity.
 This test will be positive as water is the external phase.
 An assembly consisting of a pair of electrodes connected
to a lamp is dipped into an emulsion.
 If the emulsion is o/w type, the lamp glows.
PH 201.43
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…… Electrical Conductivity Test
……
Electrical
Conductivity Test
…… Electrical Conductivity Test For oil in water emulsion F o r w a t e

For oil in water emulsion

Electrical Conductivity Test For oil in water emulsion F o r w a t e r

For water in oil emulsion

PH 201.43 25
PH 201.43
25
4. Cobalt Chloride Test When an emulsion is added to a dried filter paper soaked
4. Cobalt Chloride Test When an emulsion is added to a dried filter paper soaked
4. Cobalt Chloride Test When an emulsion is added to a dried filter paper soaked

4. Cobalt Chloride Test

When an emulsion is added to a dried filter paper soaked in cobalt chloride solution, it turns from blue to pink, indicating that the emulsion is o/w type.

Cobalt chloride paper (Dried)

that the emulsion is o/w type. Cobalt chloride paper (Dried) If oil is the continuous If
that the emulsion is o/w type. Cobalt chloride paper (Dried) If oil is the continuous If
If oil is the continuous If water is the continuous phase phase
If oil is the
continuous
If water is the
continuous
phase
phase
Turns pink Remains same PH 201.43 26
Turns pink
Remains same
PH 201.43
26
5. Fluorescence Test If an emulsion on exposure to ultra-violet radiations shows continuous florescence under
5. Fluorescence Test
If an emulsion on exposure
to ultra-violet radiations
shows
continuous florescence under
microscope w/o
Spotty fluorescence
o/w
florescence under microscope w/o Spotty fluorescence o/w Emulsion On exposure to UV light O/W Emulsion W/O
florescence under microscope w/o Spotty fluorescence o/w Emulsion On exposure to UV light O/W Emulsion W/O

Emulsion

under microscope w/o Spotty fluorescence o/w Emulsion On exposure to UV light O/W Emulsion W/O Emulsion
under microscope w/o Spotty fluorescence o/w Emulsion On exposure to UV light O/W Emulsion W/O Emulsion

On exposure to UV light

under microscope w/o Spotty fluorescence o/w Emulsion On exposure to UV light O/W Emulsion W/O Emulsion
O/W Emulsion W/O Emulsion PH 201.43 27
O/W Emulsion
W/O Emulsion
PH 201.43
27
6. Depending on the direction of creaming Most of the oils are lighter than water
6. Depending on the direction of
creaming
Most of the oils are lighter than water except clove oil.
Creaming is the formation of relatively concentrated
emulsion.
If creaming occurs at the top of the emulsion
- oil is the dispersed phase (O/W)
If creaming occurs at the bottom of the emulsion
- water is the dispersed phase (W/O)
PH 201.43
28
What is Emulsification?
What is Emulsification?
OIL Emulsifier WATER
OIL
Emulsifier
WATER
W/O
W/O

W/O

W/O
O/W
O/W
PH 201. 44 29
PH 201. 44
29
Formula emulsi oral/internal: Zat aktif  Pembawa (air dan minyak)  Emulgator  Pengawet 
Formula emulsi oral/internal:
Zat aktif
Pembawa (air dan minyak)
Emulgator
Pengawet
Bahan pembantu:
Antioksidan
Pemanis
Flavor
Pewarna
30
Formula emulsi topikal/eksternal: Zat aktif  Pembawa (air dan minyak)  Emulgator  Pengawet 
Formula emulsi topikal/eksternal:
Zat aktif
Pembawa (air dan minyak)
Emulgator
Pengawet
Bahan pembantu:
Antioksidan
Emolient
Pewangi
Pewarna
31
Formulation 1. Selection of oily phase - Toxicity of the oil - Desired consistency -
Formulation
1. Selection of oily phase
- Toxicity of the oil
- Desired consistency
- Possible chemical incompatibilities
For oral emulsions
- Mineral oils
- Edible vegetable oils
PH 201. 44
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Formulation… 2. Phase volume ratio The internal phase concentration will be determined by A. Dosage
Formulation…
2. Phase volume ratio
The internal phase concentration will be determined by
A. Dosage requirement
For O/W emulsions – 31-45% water
For W/O emulsions - < 25% water
B. Consistency desired
PH 201. 44
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Formulation… 3. Other additives in emulsion A.Viscosity builders – To buildup the viscosity of the

Formulation…

3. Other additives in emulsion A.Viscosity builders – To buildup the viscosity of the external
3. Other additives in emulsion
A.Viscosity builders – To buildup the viscosity of the external phase
Eg: Hydrocolloids
B. Antimicrobials – To protect against microbial degradation
Eg: Benzoic acid, Methyl paraben
C. Antioxidants
To protect against rancidity
Eg: BHT,BHA, Gallic acid,
Propylgallate, Tocopherols.
D. Organoleptic additives - To improve palatabilty of emulsion
Colour, Flavour and Sweetners.
PH 201. 44
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Formulation… 4. Choice of emulgent Selection based on A. B. Toxicity/ irritative Chemical incompatibility The
Formulation…
4. Choice of emulgent
Selection based on
A.
B.
Toxicity/ irritative
Chemical incompatibility
The cost
C.
Types of emulsion desired
D.
Shelf life
E.
PH 201. 44
35
Types of Emulgent  Surfactant  Hidrocolloid
Types of Emulgent
 Surfactant
 Hidrocolloid
Types of Emulgent  Surfactant  Hidrocolloid
Types of Emulgent  Surfactant  Hidrocolloid
Types of Emulgent  Surfactant  Hidrocolloid
Types of Emulgent  Surfactant  Hidrocolloid
Types of Emulgent  Surfactant  Hidrocolloid
Surfactants Cationics Nonionic Esters Quarternary Metallic soaps ammonium compounds Amine soaps Eg. Benzalkonium
Surfactants Cationics Nonionic Esters Quarternary Metallic soaps ammonium compounds Amine soaps Eg. Benzalkonium
Surfactants
Cationics
Nonionic
Esters
Quarternary
Metallic soaps
ammonium
compounds
Amine soaps
Eg. Benzalkonium
chloride
Ethers
compounds Amine soaps Eg. Benzalkonium chloride Ethers Anionics Ampholytics Alkali soaps Glyceryl monostearate
compounds Amine soaps Eg. Benzalkonium chloride Ethers Anionics Ampholytics Alkali soaps Glyceryl monostearate

Anionics

Ampholytics

Eg. Benzalkonium chloride Ethers Anionics Ampholytics Alkali soaps Glyceryl monostearate Sorbitan esters Meranols

Alkali soapsEg. Benzalkonium chloride Ethers Anionics Ampholytics Glyceryl monostearate Sorbitan esters Meranols Sulphated

Glyceryl

monostearate

Sorbitan esters

Meranols

Sulphated oilsAlkali soaps Glyceryl monostearate Sorbitan esters Meranols Brij Octoxynol Tyloxynol Ethers Esters Tweens Spans

Brij Octoxynol Tyloxynol Ethers Esters Tweens Spans
Brij
Octoxynol
Tyloxynol
Ethers Esters
Tweens
Spans

Sulphated alcoholsBrij Octoxynol Tyloxynol Ethers Esters Tweens Spans Deriphates Aliphatic sulphonates Aromatic sulphonates PH

Deriphates

Aliphatic sulphonatesBrij Octoxynol Tyloxynol Ethers Esters Tweens Spans Sulphated alcohols Deriphates Aromatic sulphonates PH 201. 45 37

Aromatic sulphonatesOctoxynol Tyloxynol Ethers Esters Tweens Spans Sulphated alcohols Deriphates Aliphatic sulphonates PH 201. 45 37

Ethers Esters Tweens Spans Sulphated alcohols Deriphates Aliphatic sulphonates Aromatic sulphonates PH 201. 45 37
PH 201. 45 37
PH 201. 45
37
NATURAL Animal Mineral Colloidal Gelatin alumina Bentonite Casein Attapulgite Milk of magnesia Wool fat Veegum
NATURAL Animal Mineral Colloidal Gelatin alumina Bentonite Casein Attapulgite Milk of magnesia Wool fat Veegum
NATURAL
Animal
Mineral
Colloidal
Gelatin
alumina
Bentonite
Casein
Attapulgite
Milk of
magnesia
Wool fat
Veegum
Casein Attapulgite Milk of magnesia Wool fat Veegum Egg yolk Magnesium HYDROCOLLOIDS I N O R

Egg yolk

Attapulgite Milk of magnesia Wool fat Veegum Egg yolk Magnesium HYDROCOLLOIDS I N O R G

Magnesium

HYDROCOLLOIDS

INORGANICS SEMISYNTHETICS

SYNTHETICS

I N O R G A N I C S SEMISYNTHETICS SYNTHETICS Carbopol Polyox Plants Acacia

Carbopol

Polyox

A N I C S SEMISYNTHETICS SYNTHETICS Carbopol Polyox Plants Acacia Tragacanth Alginates Chondron Guar gum

Plants

AcaciaI C S SEMISYNTHETICS SYNTHETICS Carbopol Polyox Plants Tragacanth Alginates Chondron Guar gum Pectin

TragacanthS SEMISYNTHETICS SYNTHETICS Carbopol Polyox Plants Acacia Alginates Chondron Guar gum Pectin Methylcellulose Carboxy

SYNTHETICS Carbopol Polyox Plants Acacia Tragacanth Alginates Chondron Guar gum Pectin Methylcellulose Carboxy

Alginates

Carbopol Polyox Plants Acacia Tragacanth Alginates Chondron Guar gum Pectin Methylcellulose Carboxy

Chondron

Guar gum

Pectin

Methylcellulose

Carboxy

methylcellulose

Hydroxy methylcellulose Microcrystalline cellulose
Hydroxy
methylcellulose
Microcrystalline
cellulose

Colloidal

silicon

dioxide

oxide

Magnesium

trisilicate

PH 201. 44 38
PH 201. 44
38
1. Bila menggunakan surfaktan a). Surfaktan (sabun)  Substansi yg larut dlm minyak  larutkan
1. Bila menggunakan surfaktan
a). Surfaktan (sabun)
 Substansi yg larut dlm minyak  larutkan dalam
minyak.
 Substansi yg larut dalam air  dilarutkan dalam
air.
 Fase minyak ditambahkan kedalam fase air sambil
diaduk.
 Substansi yg larut dalam air  dilarutkan dalam air.  Fase minyak ditambahkan kedalam fase
 Substansi yg larut dalam air  dilarutkan dalam air.  Fase minyak ditambahkan kedalam fase
 b). Surfaktan  Minyak + surfaktan (misalnya Tween dan Span)  60o - 70o
 b). Surfaktan
 Minyak + surfaktan (misalnya Tween dan Span)  60o - 70o C
 Air (60o-70oC) + kan porsi/porsi  diaduk hingga tbt emulsi
Dinginkan sampai temperatur kamar sambil diaduk.
 Temperatur dinaikkan supaya viskositas masa turun, sehingga
mempermudah pengadukan. Dengan demikian akan mempermudah
terjadinya emulsifikasi.
supaya viskositas masa turun, sehingga mempermudah pengadukan. Dengan demikian akan mempermudah terjadinya emulsifikasi.
supaya viskositas masa turun, sehingga mempermudah pengadukan. Dengan demikian akan mempermudah terjadinya emulsifikasi.
supaya viskositas masa turun, sehingga mempermudah pengadukan. Dengan demikian akan mempermudah terjadinya emulsifikasi.
2. Bila menggunakan hidrokoloid atau padatan yang terdispersi. Also called as "4:2:1" Method 4 parts
2. Bila menggunakan hidrokoloid atau
padatan yang terdispersi.
Also called as "4:2:1" Method
4 parts (volumes) of oil
2 parts of water
1 part of gum used in the preparation of
primary emulsion
Method 4 parts (volumes) of oil 2 parts of water 1 part of gum used in
Method 4 parts (volumes) of oil 2 parts of water 1 part of gum used in
Method 4 parts (volumes) of oil 2 parts of water 1 part of gum used in
Teknologi Pembuatan Emulsi Alat yg digunakan untuk membuat emulsi :  Semua alat pembuat emulsi
Teknologi Pembuatan Emulsi
Alat yg digunakan untuk membuat emulsi :
 Semua alat pembuat emulsi mempunyai karakteristik sbb :
• Membuat system terdistribusi merata •Memperkecil ukuran partikel, menghomogenkan campuran.
• Membuat system terdistribusi merata
•Memperkecil ukuran partikel, menghomogenkan campuran.
karakteristik sbb : • Membuat system terdistribusi merata •Memperkecil ukuran partikel, menghomogenkan campuran.
karakteristik sbb : • Membuat system terdistribusi merata •Memperkecil ukuran partikel, menghomogenkan campuran.
karakteristik sbb : • Membuat system terdistribusi merata •Memperkecil ukuran partikel, menghomogenkan campuran.
karakteristik sbb : • Membuat system terdistribusi merata •Memperkecil ukuran partikel, menghomogenkan campuran.
1. Mixer
1. Mixer
1. Mixer
1. Mixer
Mesin Mixing  Bahan yang ingin dicampur dimasukkan dalam inlet hole product, kemudian motor penggerak
Mesin Mixing
 Bahan yang ingin dicampur dimasukkan dalam inlet
hole product, kemudian motor penggerak utama
akan berputar dengan kecepatan tertentu untuk
memixing produk.
dalam inlet hole product, kemudian motor penggerak utama akan berputar dengan kecepatan tertentu untuk memixing produk.
dalam inlet hole product, kemudian motor penggerak utama akan berputar dengan kecepatan tertentu untuk memixing produk.
2. Blender  Perbedaan dengan mixer?
2. Blender  Perbedaan dengan mixer?

2. Blender Perbedaan dengan mixer?

2. Blender  Perbedaan dengan mixer?
2. Blender  Perbedaan dengan mixer?
2. Blender  Perbedaan dengan mixer?
Homogenizer ultra turrax  Ultra turrax® digunakan untuk menghomogenisasikan partikel. Alat ini memberikan gelombang
Homogenizer ultra turrax  Ultra turrax® digunakan untuk menghomogenisasikan partikel. Alat ini memberikan gelombang
Homogenizer ultra turrax
Homogenizer ultra turrax
 Ultra turrax® digunakan untuk menghomogenisasikan partikel. Alat ini memberikan gelombang  ultrasonik. Dengan
Ultra turrax® digunakan untuk
menghomogenisasikan partikel.
Alat ini memberikan gelombang
ultrasonik. Dengan tingginya
kecepatan rotasi dari rotor, membuat
suatu media secara langsung tertarik
ke arah sumbu poros lalu menyebar
keluar sumbu poros melalui slot rotor
dalam stator. Adanya gelombang
tersebut akan mengakibatkan partikel
pecah menjadi ukuran yang lebih
kecil.
Kerja ultra turrax® yang menggilas
dan memotong membuat partikel
menjadi ukuran yang lebih kecil dan
membuat partikel menjadi homogen.
yang menggilas dan memotong membuat partikel menjadi ukuran yang lebih kecil dan membuat partikel menjadi homogen.
yang menggilas dan memotong membuat partikel menjadi ukuran yang lebih kecil dan membuat partikel menjadi homogen.
Ultra Turrax skala Industri
Ultra Turrax skala Industri
Ultra Turrax skala Industri
Ultra Turrax skala Industri
 Any Question?
 Any Question?
 Any Question?
 Any Question?
 Any Question?
 Any Question?
 Any Question?
 Any Question?
 Any Question?
 Any Question?
 Any Question?
 Thank you…
 Thank you…
 Thank you…
 Thank you…
 Thank you…
 Thank you…
 Thank you…
 Thank you…
 Thank you…
 Thank you…
 Thank you…