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Developing Engineering Thinking during an Ill-Structured Activity for

Kinetics and Reactor Design: A Technology Solution
Koretsky, M. D. (2015). Program level curriculum reform at scale: Using studios to flip
the classroom. Chemical Engineering Education, 49(1), 47-57.

Studio structure: large lecture sections (100 - 350 students) are interspersed with
smaller studio meetings (approximately 24 students). In studios, students work together
in mostly 3-person teams, facilitated by trained graduate student teaching assistants.
Studios are designed to extend students’ thinking and problem-solving techniques while
simultaneously reinforcing core content and developing teamwork and communication
skills. In its original manifestation, Studio 1.0, the activity relied on sequestered,
worksheet-based problems to help students identify and practice key conceptual and
procedural knowledge, and connect that understanding to lecture, but the activities were
clearly limited in developing students’ ability to connect the activity to professional practice
and to develop value systems corresponding to the profession.
In the Studio 2.0 reform, a shift in activity and re-situate learning by engaging students
in meaningful, consequential work that directly and clearly relates to professional practice
and desired professional attitudes and behaviors. The intent for these experiences is to
provide a foundation for development of students’ chemical engineering identity.
Rather than attempting to direct students procedurally to a “correct” solution, a Studio 2.0
memorandum might explain a situation where a company is seeking to optimize a
particular process and ask students to collaboratively decide on and perform calculations
to make a design recommendation. Assessment is formative and immediate, focused
on whether teams are “making progress” in grappling with the task. In this framing, as
learners struggle with difficult concepts and may even sometimes fail to accomplish their
short-term goals, they are continually positioned as engineers seeking meaningful
progress towards a viable solution, rather than students following directions to get a
Presented a four-hour studio progression where students work in teams in studio on a
situated problem where they must determine the rate constant for a sugar reaction and,
importantly, recommend a time for manufacturing to yield a minimum conversion. We
have developed a technology-based solution where the teams are provided data that is
generated by simulation. Each team has two reactors to work with and the simulation
generates unique results for the team. Variation is added mandating the teams apply
statistical reasoning in addition to utilizing their knowledge of kinetics. For some teams,
the reactors are different, for others they are the same. The technology solution
prompts students to respond to a set of prompts in which they report their findings
and engineering recommendations and justify them. how students within the same
team (with the same data sets) align, and how we can interpret the results to improve the
activity design. goal is to automate these assessment processes to provide an instructor
a broad understanding of the choices students are making that supports delivery and
assessment of more authentic ill-structured tasks.

2. Reading and Repetition Using an Interactive Textbook for Material and

Energy Balances
3. Check Your Homework with Your Phone
John Wagner Trine University
Unlike traditional paper-based problems, each student receives a different version of the
problem. In addition, the printed file contains a QR Code and website where students
can check their responses with their phone or computer. Context specific instructional
materials are provided on the website for students who need instructional support.
Besides homework problems, this system lends itself to in-class practice and group
problems especially for classrooms that are not equipped with computers.

problems tested in several chemical engineering classes including Energy Balances,

Thermodynamics, and as a curriculum review in Chemical Process Design I.
The proposed system combines the flexibility and efficiency of a paper-based system with
many of the advantages of a computer-based system and allows students to get
immediate feedback utilizing their cell phones.

4. Educational Augmented Reality Tools: Development, Implementation, and

Assessment of Phase I
Konstatinos Kakosimos
Investigated use of AR to enhance the instructional experience of engineering students.
A team of three faculty, one laboratory staff, two students, and an external programmer
developed a visual support tool as a means to improve learning of chemical engineering
students engaged in a specific laboratory activity while mitigating the challenges of
laboratory work. The pilot consists of 30 students, from multiple levels. The experimental
evaluation showed encouraging results, 43% showed significant and marginal
improvements on the learning outcomes. A tremendous impact on the learning attitude
was observed while impressive satisfaction and significant cognitive validity were
captured in the self-surveys. To the best of our knowledge, there are very few similar
efforts in engineering education and here we share the experiences gained during the
development, implementation and assessment of EduART.

5. Preparing Chemical Engineering Students for the Digitalization of Tomorrow

– Integrating Modelling across the Curriculum
Eva Sorensen and Pieter Schmal
System supports that modelling is integrated across the entire curriculum, rather than
being covered in a single course in the junior or senior year. To support the integration,
training material, exercises and tests developed and provided through the Process
systems engineering Academic Teaching Highway (PATH) initiative. The material is
modular in nature and covers the typical fundamental topics from a modelling perspective
and are supplementary to existing course material. Implementation and delivery of the
new curriculum over the past four years, and how the PATH material has supported the
students' learning, ultimately preparing them for a digital future
6. Aspen Plus®Videos for Chemical Engineering Undergraduates

Michael Shao
Introduced ASPEN Plus® in the sophomore level Material and Energy Balance (MEB)
course using videos and handouts created by an undergraduate who has taken the
course to teach MEB students how to create a chemical process. The presentation
shows how the videos were created using Camtasia Studio 9 screen capture software,
the advantages of traditional learning via handouts and more innovative learning
through videos, and benefits of a “student teaching students” learning experience.
The goal of the speaker (junior CPE undergraduate) is to create ASPEN Plus® training
modules for each course of the KU CPE curriculum. Thus, by graduation, a library of
videos will be available for students to use in all the chemical engineering courses at

7. The Current State of the Knowledge: Wax Deposition Modeling and Up

Scaling Challenges
Natu Darabiona
Wax deposition causes major flow assurance issues for offshore production systems.
This deposit may not only get thicker, but also get harder over time. As it gets harder, the
deposit removal process becomes more difficult. Proper understanding of wax deposition
behavior is required to develop accurate deposition models and cost-effective
management strategies. Available models rarely achieve acceptable agreement with
experimental data without fitting parameters, to the extent that more than 100%
uncertainty is common. It is necessary to identify the sources of uncertainty to improve
the model capability and up scaling efforts. Showed current state of the knowledge and
limitations on wax modeling in upstream pipelines.

8. Prospects of Amino Acids and Ionic Liquids As a Potential Gas Hydrate

Inhibitors for Offshore Flow Assurance
M. Fahed Qureshi
The gas hydrates are crystalline ice-like compounds that are formed under high pressure
Formation of hydrates is considered a major flow assurance issue in the oil and gas
Annually, it is reported that the oil and gas industry spends over 200 million US $ on the
purchase of chemical inhibitors like methanol and mono-ethylene glycol, to prevent
the risk of hydrate formation by shifting the hydrate vapor liquid equilibrium (HVLE) curve
to lower temperatures. However, these thermodynamic inhibitors are required in high
dosage (> 30 wt%), they are toxic, flammable and there are environmental constraints
associated with the disposal of these inhibitors. Therefore, the industry is in the quest of
finding hydrate inhibitors that are environmentally benign, economical, required in low
dosage and easily disposable.
Amino acids are biological compounds that naturally exist in nature and are considered
as building blocks of life. The amino acids due to their inherited eco-friendliness and
enhanced biodegradability do have a potential to act as the hydrate inhibitors. Ionic
liquids are organic salts that have a low melting point and negligible vapor pressure. To
determine the prospects, of amino acids and ionic liquids as future potential hydrate
inhibitors have been experimentally tested at different pressures and concentrations.
All the experimental work has been conducted using pure methane gas and rocking cell
assembly (RC-5) under diverse operating conditions (40-120 bars). Tested five
commercially available amino acids and four specially synthesize ammonium based ionic
liquids as hydrate inhibitors on pure methane gas. The dual functional behavior of ionic
liquids and amino acids has also been investigated and the results obtained have been
compared with the conventional hydrate inhibitors like methanol and mono-ethylene
glycol. Accordingly, the synergistic effect of a water soluble polymer on the hydrate
inhibition effectiveness of amino acids and ionic liquids has also been tested.

9. Effect of Stirring on the Hydrate Formation Rate for Natural Gas Storage and
Transportation Perspective
M. Fahed Qureshi
The liquefaction of natural gas (LNG) is an energy intensive and complex process, which
requires the cooling of natural gas up to -161oC. Therefore, the interest of academic and
industrial researchers is shifting towards the use of hydrates as the mode of natural gas
transportation and storage.
Transporting natural gas in the form of hydrates requires the conversion of natural gas
into hydrate bulky crystals by cooling natural gas until the optimum temperature and then
refrigerating at the suitable temperature of about -10 OC. This process compared to LNG
seems to be simple and less energy intensive. The hydrate formation rate is the key
when it comes to the conversion of natural gas to the hydrates determined by stirring
rate or agitation of gas-water mixture. Evaluated effect on Hydrate formation rate
varying stirring rates (100-1400 RPM) using high pressure cell that consist of a magnetic
stirrer. Gas mixture consist of four components such as methane, ethane, carbon
dioxide and nitrogen. Carried out under high pressure of 98 bars and variable stirring
rates (100-1400 RPM). The experimental results indicate that there exists a threshold
limit above and below which no hydrate formation occurs. This shows that optimum
stirring rate is necessary to facilitate the conversion of natural gas into the hydrates.
10. A Deep Neural Net Model for Oil/Water Separation in Oil Production Pipelines
Kuochen Tsai

Most simulations can be costly due to expensive computational requirements. Study,

used a deep neural network model trained by CFD simulations capable of predicting
oi/water separation in horizontal oil pipelines was developed to accelerate and replace
the CFD simulations. The CFD model was developed previously for oil/water separation
in horizontal pipelines to predict the water wetting probability on carbon steel pipeline
surfaces. The model correctly reproduce the flow regime map widely used in industry
across ranges of water cut, mixture velocity, pipe diameter, oil density, viscosity and
surface tension. However, the model requires expert set up and can take days to
complete. Recently deep learning neural network algorithms can automate the correlation
construction between input and output data and allows complex hyper-dimensional
correlations to be built with high accuracy. The efficiency comes from the optimization
procedure unique to convolutional neural network (CNN) models. By parametrizing the
CFD simulations it is possible to pre-calculate the results in all the necessary parametric
spaces and use them to train the CNN model. Presents preliminary results in two
parametric spaces, water cut and mixture velocity, are presented. The trained CNN
model showed very high accuracy with the mean square errors lower than 0.01 in all
cases. A total of ~4,000 data points were used to train the CNN model. The training time
was around 4 minutes, and the inferencing time was less than 5 milliseconds, a
performance gain of 106 in comparison to the CFD simulations. The model is being
extended to include the other parameters aforementioned. It can also be extended to
model other types of predictions as well, such as erosion and corrosion, and with more
complex geometries other than straight pipes.

11. End to end management and visualization system for cell culture process
Brian Doyle
Excel is limited in its processing capabilities, ability to directly compare differently sized or shaped
data sets, and ease in flexibly creating and formatting graphics. Using Excel as a repository and
analytical tool for comparison of data between experiments, bioreactor scales, laboratories, or
manufacturing facilities requires an inefficient and labor intensive workflow of manual transfers
and manipulations that is error prone, difficult to control, and time consuming. Developed an
end-to-end data management and visualization system to meet user requirements while presenting
familiar and user friendly interfaces that are accessible to both highly trained laboratory personnel
as well as site leadership.
In the cell culture process development laboratory, the core of the system is a customized control
system implementation for process control, coordination of run metadata, and automation of
process execution. A PI server archives data from the process control system and in-process
analyzers; parallel data streams from pilot plant and clinical manufacturing campaigns are shared
into the historian across enterprise level PI connections. PI data from active and historic runs across
all scales can be queried and retrieved by PI client applications for real-time visualization and
comparison or ad-hoc analysis. Archived data from all sources are processed through a routine to
automate data interpolation, alignment, and calculations. Processed data is available in a relational
SQL database for use by powerful visualization, business analytics, and analytical software.
This system has replaced Excel as the primary access point to cell culture data, reducing labor and
risk of errors by automating the data management process. It has enabled flexible comparison and
more valuable visualization and analysis of data across runs and scales which previously were not
feasible. We envision this system to have applicability from process development studies to
ongoing monitoring of manufacturing campaign data and to be expandable to be inclusive of
process data from contract manufacturing facilities and product quality analytical data.
12. Driving towards structured nucleic acid
Understanding nucleic acid evolution without use of enzymes. Challenge is product/strand
inhibition. However viscous glycoline though not too viscous to pose a challenge can be used to
overcome the problem. Strands can be copied. Design of experiment: dry glycoline, aqueous
buffer, heating and cooling: here we see full copying. Different cycle has been designed to see the
thermodynamic effect (controlling humidity and temperature). Viscous solvent can be used kinetic
and thermodynamic trap strands.
13. Analysis of a PEMFC
Polarization curve:
A: catalyst
O: Ohmic losses
C: poor gas diffusion, presence of water
Nanofiber electrospinning though pure Nafion cannot be spinned because it contains taflon
backbone hydrophilic and hydrophobic tail. To improve this we can improve oxygen reduction
catalyst. Consider selectivity, stability, activity. They used Pt/Ni to boost current density both high
and low humidity