GO to Transaction SMQR to stop the inbound queues at APO /ECC :

Check for the CF* queue name

Select the deregistration Button in the below menu

 Once deregistration done , the queue selected mode will be with TYPE U . refer below
screenshot.

Once CIF queues are stopped .

Create and run the Integration model in CFM1 and activate it in CFM2 in ECC.
Goto CFM2
Click start on the above button screenshot . Then there will be a POPUP that there are CIF queues
blocked at APO . Click ignore and proceed .OPen APO system and see if queues are Blocked.\

Now open SMQ2 in APO system and see the queues are blocked . check the status of the queues in
NO EXEC status.

Select the stopped queue and reset the Queue status from NOEXEC to READY STATUS.

After reset, select the same queue and click debug LUW , now the debugger is ON.

Similarly to block the outbound queues in APO go to smqs (Outbound queue scheduler) and select
CF* queue to deregister it . once deregistered Exceute the transaction /sapapo/c5 to send the
generated orders in APO to ECC .see the queues are stopped in transction SMQ1 in APO . After
resetting the status , you can debug the luw in APO .