List of Antidotes

Antidotes to Common Medications

No. Drugs Antidote
01
Acetaminophen N-Acetylcysteine or Mucomyst

02
Anticholinesterase Atropine or Pralidoxime

03
Anticholinergics, diphenhydramine, dimenhydrinate Physostigmine

04
Antifreeze Fomepizole, Ethanol

05
BenzodiazepinesZaleplonZolpidem Flumazenil (Romazicon)

06 Beta-Blocking agents, Calcium channel blockers,

Glucagon, Epinephrine
Hypoglycemia, Hypoglycemic agents
07
Calcium Channel Blockers Calcium Chloride, Glucagon

08
Coumadin Phytonadione or Vitamin K

09
Cyanide Amyl nitrite, sodium nitrite, sodium thiosulfate

10
Cyclophosphamide Mesna

11
Digoxin Digibind or Digoxin Immune Fab

13
Heroin Naloxone (Narcan) or Nalmefene

14
Iron Deferoxamine

15
Heparin Protamine Sulfate

16
Lead EDTA, dimercaprol, succimer

18
Methotrexate Leucovorin calcium

19
Potassium Insulin + Glucose, Kayexalate

20
Methanol Folic acid

21
Valproic acid L-Carnitine

22
Sulfonylureas Octreotide (Sandostatin )

23
Isoniazid, ethylene glycol Pyridoxine HCl (Vitamin B6)

24 Sodium channel blockers (e.g. cyclic antidepressants),

Sodium Bicarbonate
salicylates
25
Ethylene glycol Thiamine

Calcium channel blockersFluoride salts (e.g.,

26
NaF)Hydrofluoric acid (HF)Hyperkalemia (not digoxin- Calcium chloride andCalcium gluconate
induced)Hypermagnesemia
27
Ethylene glycolMethanol Ethanol

Alpha agonists (e.g., clonidine), Opioids (e.g., codeine,

28
diphenoxylate, fentanyl, heroin, meperidine, morphine and Naloxone
propoxyphene)
29
Arsenic, Copper, Lead, Mercury D-Penicillamine (Cuprimine )

Local anesthetics and possibly othercardiac toxins (e.g.,

30
bupropion, calciumchannel blockers, cocaine, beta blockers, Fat emulsion (Intralipid , Liposyn II , Liposyn III )
tricyclic antidepressants)