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Ischaemic Heart Disease (IHD)

In those AT RISK:
CASE DEFINITION Ask annually about symptoms of IHD:
Ischaemic heart disease (IHD) consists of a range of clinical  CLASSICAL symptoms include crushing central chest
syndromes resulting from atherosclerosis (blockages) in the Absolute contraindications to stress testing*:
pain with associated SOB, nausea and vomiting.
coronary arteries. This includes: Acute myocardial infarction or new LBBB, high risk unstable
 ATYPICAL symptoms include atypical chest pain (eg angina, symptomatic severe aortic stenosis, uncontrolled
1. PREVIOUSLY DOCUMENTED IHD INCLUDING: vague chest discomfort, sharp pain, “indigestion”),
arrhythmia which is symptomatic or with haemodynamic
- previous myocardial infarction (MI)/”heart attack” shortness of breath without associated chest pain
instability, unstable heart failure, acute pulmonary embolus,
and sudden change in exercise tolerance.
- previous unstable angina (ie. any new symptoms of acute aortic dissection
IHD once MI excluded, symptoms of IHD that have PRINCIPLES OF MANAGEMENT
become more severe, prolonged or frequent on Relative contraindications to stress testing*:
background of stable angina, symptoms of IHD at Left main coronary stenosis, severe arterial hypertension,
rest))
This protocol is not for treatment of acute
electrolyte abnormalities, hypertrophic obstructive
- previous abnormal coronary angiogram
cardiac ischaemia. Please refer to local chest cardiomyopathy, uncontrolled arrhythmia
pain protocols. *If present discuss with cardiologist/physician
2. STABLE ANGINA:
- symptoms of IHD occurring at the same exercise Assessment: After an admission:
threshold and no symptoms at rest
Document CAD risk factors (see ‘Screening’).  Chase discharge summary and reports of
3. ASYMPTOMATIC CORONARY ARTERY NARROWING
angiography
- which can cause silent MI or ischaemia Document BP, pulse, BMI, waist circumference.
 HbA1c Non-Pharmacological Management
 FBC, UEC, eGFR, LFT’s, lipids, urine ACR.  Encourage smoking cessation (see SMOKING
SCREENING  CXR as soon as practical. CESSATION) and healthy diet (see HEALTHY LIVING)
RISK FACTORS for IHD include:  Baseline ECG (at least 5yrly in patients at risk,  No alcohol is best
 Smoking yearly in patients with Type 2 DM)  Exercise– encourage walking or aerobic exercise for
 Aboriginal ethnicity Investigate symptoms suggestive of stable angina and confirm 30 minutes at least 5 days each week.

 Diabetes
diagnosis by:  Manage other CAD risk factors

 Family history (1st degree relative with onset of  Stress ECG; OR  Be aware of co-existent heart failure (See HEART
CAD at age < 65 yrs if female and < 55 yrs if male).  Dobutamine stress ECHO (for patients who are FAILURE)

 Hypertension unable to physically to undertake a stress  If available locally, refer motivated patients for
ECG/ECHO); OR cardiac rehabilitation
 ACR > = 3.6 mg / mmol and/or known chronic
kidney disease (see protocol)  Stress ECHO. Best used in these patient groups:  Ensure influenza (annual) and pneumococcal 23PPV
o Left bundle branch block or abnormal ST vaccinations (at age 60 & 65yrs or ATSI patients >
 Dyslipidaemia 15yrs, two vaccinations, 5 years apart) are up to
segments on resting ECG
 Obesity as defined by BMI > 30 or waist date
o Perimenopausal women
circumference in men >94cm and in women >80cm.
*Consider wait times and availability when choosing
which stress test to request*
© Kimberley Aboriginal Medical Services Ltd (KAMS) and WA Country Health Service (WACHS) Kimberley – Reviewed April 2017
Ischaemic Heart Disease (IHD)
THERAPEUTIC PROTOCOLS  If angina continues: Add nifedipine SR 30mg daily WOMEN OF CHILD BEARING AGE
and double the dose to 60mg daily after 2 weeks as
needed (caution use in heart failure) Encourage use of reliable contraception, pre-pregnancy
Suspected IHD counseling and early antenatal care
 Then if pain continues add nicorandil 5mg BD and
1. Aspirin 100mg daily (if contraindicated use clopidogrel double weekly to maximum dose 20mg BD IF PREGNANT:
75mg daily)
 Discuss with obstetrician/physician as soon as
2. If HR > 60 bpm use a beta blocker Post Myocardial infarction pregnancy is confirmed.
 Atenolol 50mg daily, double dose after 2 weeks to As for stable angina:  With specialist input review medications, including:
maximum 100mg daily. (If contraindications discuss o nitrates, nicorandil, ACEIs and statins
with physician). 1. Aspirin 100mg daily (if contraindicated use clopidogrel 75mg daily)
2. If HR > 60 use a beta blocker o substitution of atenolol with labetalol
 If associated heart failure use bisoprolol (see HEART
FAILURE)  Atenolol 50mg daily, double dose after 2 weeks to maximum 100mg o aspirin and GTN (if indicated)
daily. (If contra-indications discuss with physician).
If HR <60 use isosorbide mononitrate MR IF BREASTFEEDING:
 If associated heart failure use bisoprolol (see HEART FAILURE)
 30mg daily doubling dose every 2 weeks to If HR <60 use isosorbide mononitrate MR
 AVOID statins, nitrates and nicorandil
maximum of 120mg daily  30mg daily doubling dose every 2 weeks to maximum of 120mg daily  Continue aspirin 100mg daily
3. Glyceryl trinitrate (GTN) 400mcg pump spray to use PRN 3. Glyceryl trinitrate (GTN) 400mcg pump spray to use PRN  If ACEI required, use enalapril 2.5-40mg
AND  If on beta blocker change to metoprolol or labetolol
Stable Angina
Regardless of initial lipid status ADD a statin (atorvastatin 40mg, increasing to  If on nifedipine continue
As for suspected IHD: 80mg) (See DYSLIPIDAEMIA).
IF EPISODES OF ANGINA PERSIST: FOLLOW UP
1. Aspirin 100mg daily (if contraindicated use clopidogrel 75mg daily)  Add isosorbide mononitrate MR 30mg daily (if not taking already) and
double every 2 weeks to maximum 120mg once daily Review patients within 1 week of any hospitalisation and
2. If HR > 60 use a beta blocker every 2 weeks when titrating medications
 If angina continues: Add nifedipine SR 30mg daily and double the dose
 Atenolol 50mg daily, double dose after 2 weeks to maximum 100mg to 60mg daily after 2 weeks as needed (caution use in heart failure)
daily (If contraindications discuss with physician) STABLE IHD:
 Then if pain continues add nicorandil 5mg BD and double weekly to
 If associated heart failure use bisoprolol (see HEART FAILURE) maximum dose 20mg BD  3 monthly: review angina symptoms. Check BP, BMI,
If HR <60 use isosorbide mononitrate MR
waist circumference and smoking status.
 30mg daily doubling dose every 2 weeks to maximum of 120mg daily  6 monthly: UEC, eGFR.
AND
3. Glyceryl trinitrate (GTN) 400mcg pump spray to use PRN  Annually: ECG, ACR, HbA1c
 Treat hypertension (BP >120/80) with ramipril,
AND starting with 2.5mg daily (see HYPERTENSION) REFER/DISCUSS
Regardless of initial lipid status ADD a statin (atorvastatin AND
CARDIOLOGIST +/- PHYSICIAN (for local input)
40mg daily, increasing to 80mg) (See DYSLIPIDAEMIA).  Check patient’s anticoagulant medications which
 newly diagnosed unstable angina
may be commenced on admission. Confirm the
IF EPISODES OF ANGINA PERSIST:  persisting angina despite maximal therapy
duration of planned therapy
 Add isosorbide mononitrate MR 30mg daily (if not  contraindications to stress testing
taking already) and double every 2 weeks to
maximum 120mg once daily  significant comorbidities eg heart failure, chronic
renal failure and valvular heart disease
© Kimberley Aboriginal Medical Services Ltd (KAMS) and WA Country Health Service (WACHS) Kimberley – Reviewed April 2017

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