Vial

Adapters
E nable needle-free drug
transfer and reconstitution
Vial adapters are the cost-effective solution for the safe and rapid
transfer and reconstitution of drugs between vials and syringes. Our
vial adapter spike technology provides a reproducible engineered depth
for drug and diluent aspiration, which greatly reduces the
end-user variability associated with traditional needle
aspirations. That means you can assure the most efficient
and cost-effective vial overfill volumes for your drug
product.
Vial Adapters
• Reduces exposure to needle-stick injuries
• Fewer steps, parts and sharps
• Reduce costly overfill requirements

Options
• Siliconized spike reduces insertion force
• In-line fluid path filters reduce particle transfer

Vented Vial Adapter

• Dual-channel spike facilitates rapid large-volume
withdrawal without pressurizing vial
• Reduces sprayback potential of toxic materials through
pressure equalization
• The design allows sterile inbound air and proper aspiration
• PTFE 0.2 micron hydrophobic air filter

Swabable Vial Adapter

• Silicone rubber valve with Luer-compatible connector
maintains sterility for repeat vial access
• Eliminates coring and stopper integrity issues associated
with multi-dose rubber stoppers
• Opens only when connected to/compressed by standard
Luer slip or Luer lock syringe
• Swabable surface to insure sterility

Vial adapters are 510(k) cleared by the United States Food and Drug Administration and
carry the CE mark.

North America South America Europe Asia Pacific

1-800-345-9800 +55 11 4055 6061 +49 (0) 2403-7960 +65 6862 3400
option 8
www.WestPharma.com • www.WestReconstitution.com
West Pharmaceutical Services, Inc. • 530 Herman O. West Drive • Exton, PA 19341

West and the diamond logo and By your side for a healthier world™ are registered trademarks or
trademarks of West Pharmaceutical Services, Inc., in the United States and other jurisdictions.
Copyright © 2014 West Pharmaceutical Services, Inc. #7250  •  0214
Dosing
Accuracy
Needle-Free Vial Adapters Reduce Drug Overfill
Drug overfill is a costly practice that is based Ordinary drug With West
withdrawl vial adapter
upon the variability in drug withdrawal technique
when using a needle. Typical overfill volumes in
use today vary from 10% to 30% of label claim.
The West reconstitution and transfer systems
with fluid openings on the side of the plastic
spike allows for greater consistency in drug
withdrawal and reduced overfill requirements.
This lowers your cost per vial and increases the
number of doses per lot. For example, reducing
the overfill by 20% provides enough drug for one
additional vial for each five vials filled.

Study Shows Consistent Delivered Volume

A West study showed greater consistency in drug withdrawal using a vial adapter
compared to a syringe and needle. The study groups consisted of 10 nurses and
10 hemophilia patients, neither having previously used vial adapters. A control group
consisted of four experienced lab analysts experienced with using vial adapters.

Needle and Syringe Versus Vial Adapter for 2 mL Solution Withdrawal

Needle and Syringe Vial Adapter

Overfill Required % Overfill for 2.0 mL Overfill Required % Overfill for 2.0 mL

Patients 0.711 mL 35.6% 0.142 mL 7.1%

Nurses 0.318 mL 15.9% 0.172 mL 8.6%

Lab Analysts 0.306 mL 15.3% 0.0750 mL 3.8%

The data clearly show more consistent fluid withdrawal with the vial adapter across all
groups of users.

Reducing the Need for Costly Overfill of Drug Vials

For drug companies, evaluation of vial overfill using vial adapters should be initiated
early in formulation development. The result can lead to lower API costs and increased
amounts of commercially available drug product.

North America South America Europe Asia Pacific

1-800-345-9800 +55 11 4055 6061 +49 (0) 2403-7960 +65 6862 3400
option 8
www.WestPharma.com • www.WestReconstitution.com
West Pharmaceutical Services, Inc. • 530 Herman O. West Drive • Exton, PA 19341

West and the diamond logo and By your side for a healthier world™ are registered trademarks or
trademarks of West Pharmaceutical Services, Inc., in the United States and other jurisdictions. Vial
adapters are 510(k) cleared by the United States Food and Drug Administration and carry the CE mark.
Copyright © 2014 West Pharmaceutical Services, Inc. #7250  •  0214