PATHOPHYSIOLOGY

Hormonal Renal problem Diabetes mellitus Age factors Polyhydramnios

changes and multifetal
gestation
Normal Insufficient Rejection Teenage Above
Alteration on the
progesterone insulin of insulin 35 y/o
body’s equilibruim Congestion
action
of nearby
organs
Insulin Increased blood Hormonal incapacity
Malnutrition Fluid deficit
antagonist glucose level
Kidneys
Inability to adjust to
Alteration in the functioning of Human Decrease glucose hormonal changes
the kidney placental reaches the cells
lactogen for consumption
Greater chances or
Altered Affects the Abnormal more severe
blood rennin- excretion Decrease cell malnutrition and fluid
productio angiotension- of protein functioning deficit
n aldosterone (including kidneys)
system
Decreased Proteinuria
platelet
count
Albuminemia

Risk for Increased intrauterine pressure

Fluid shifting
bleeding
among
compartments Congestion of the placenta

Edema Decreased placental perfusion

Hypovolemia Altered Placental hormone Decreased fetal

skin imbalance circulation
integrity
Aggravates
kidney Affects maternal
Fetal Placental
problem circulation
malnutrition infarction

Oliguria or
anuria SGA Stillbirth

Increased vascular
reistance

Hypertension
 Hypertension

Maternal effects Fetal effects

BRAIN KIDNEYS UTERUS Decreased

placental
Along with other circulation
hormonal chnages Aggravation of insult Decreased
placental
Chemical
perfusion Decreased delivery
imbalance Damage of some parts of oxygen and
essential nutrients
Hyperexcitation More insult Damage of SGA
to blood membrame
Shrinking Fetal
regulating oligohydr
Increased ICP of placenta malnutrition
system amnios
Increased
protein
Hyperirritability Congestion of excretion Abruption
nerves placentae

Convulsions Decreased
Visual osmolarity
disturbances
Coma
Increased
edema
Blurred

Halo

Dim

Blind spot

Disorientation

Severe headache

Irritability

Hyperreflexia