DAFTAR ISI

Halaman

KATA PENGANTAR .......................................................................... i

DAFTAR ISI ......................................................................................... ii

BAB I PENDAHULUAN

1.1 Latar Belakang ..................................................................... 1

1.2 Rumusan Masalah ................................................................ 1
1.3 Tujuan Masalah .................................................................... 1
1.4 Manfaat Makalah ................................................................. 2
1.5 Metode Makalah ................................................................... 2

BAB II KAJIAN TEORITIS

2.1 Definisi Tetes Mata .............................................................. 3

2.2 Keuntungan dan Kerugian .................................................... 4

2.3 Faktor Penting Dalam Sediaan Tetes Mata

2.3.1 Syarat – syarat Sediaan Tetes Mata .......................... . 4
2.3.2 Faktor Penting ......................................................... .. 4
2.3.3 Pemilihan Bentuk Zat ............................................... . 5
2.3.4 Suspensi mata .......................................................... .. 6
2.3.5 Karakteristik Sediaan Mata ...................................... . 7
2.3.6 Penggunaan Tetes Mata ........................................... .. 9
2.4 Siklosporin ........................................................................ ... 9
2.5 Dry Eye Sindrome ............................................................. ... 10

BAB III METODOLOGI

2.3 Bahan .................................................................................... 11

3.2 Formulasi Tetes Mata ........................................................... 11

3.3 Analisis Kuantitatif .............................................................. 12

3.4 Fraksi Obat Padat ................................................................. 12

3.5 Pengukuran Spektroskopi .................................................... 13

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 3.6 Hamburan Cahaya Dinamis ................................................. 13

3.7 Mikroskop ............................................................................ 14

3.8 Sifat Fisikokimia ................................................................ .. 15

3.9 Studi In Vivo ..................................................................... ... 16

BAB IV PEMBAHASAN

4.1 Formulasi Tetes Mata ......................................................... .. 18

4.2 Sifat Fisikokimia ................................................................ .. 18
4.3 Analisis Partikel
4.3.1 Fraksi Obat Padat ..................................................... .. 19
4.3.2 Studi Spektroskopi Dari Supernatan ......................... . 19
4.3.3 Ukuran Partikel ........................................................ .. 19
4.4 Evaluasi Toksikologi ............................................................ 21

BAB V PENUTUP

5.1 Simpulan .............................................................................. 22

5.2 Saran ..................................................................................... 22

DAFTAR PUSTAKA ........................................................................... 23

LAMPIRAN .......................................................................................... 24

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