PROPOSAL PROGRAM KREATIVITAS MAHASISWA

INOVASI KRIM KOMBINASI MINYAK IKAN SIDAT (Anguilla bicolor)

DAN GAMAT (Holuthoria leucospilota) SEBAGAI AGEN
ANTIINFLAMASI PADA MODEL HEWAN UJI MENCIT GALUR
BALB/C YANG DIINDUKSI CROTON OIL

BIDANG KEGIATAN:
PKM PENELITIAN

Diusulkan Oleh:

Waliyyin Razan Qanit M0615047 Angkatan 2015

Raka Sukmabayu Weninggalih Sugiantoro M0614045 Angkatan 2014
Agung Putu Surya Purna Kristyawan M0616002 Angkatan 2016

UNIVERSITAS SEBELAS MARET

SURAKARTA

2017

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 PENGESAHAN PROPOSAL PKM-PENELITIAN

1. Judul Kegiatan : Inovasi Krim Kombinasi Minyak Ikan

2. Bidang Kegiatan
3. Ketua Pelaksana Kegiatan
a. Nama Lengkap
b. NIM
c. Jurusan
d. Universitas
e. Alamat Rumah dan
No. Tel/HP
f. Alamat Email
4. Anggota Pelaksana
5. Dosen Pendamping
a. Nama Lengkap dan Gelar
b. NIDN
c.Alamat rumah dan No. HP
6. Biaya Kegiatan total
a. Kemristekdikti
b. Sumber lain
7. Jangka waktu pelaksanaan
Menyetujui,
Dosen Pendamping
Sidat (Anguilla bicolor) dan Gamat
(Holuthoria leucospilota) sebagai Agen
Antiinflamasi pada Model Hewan Uji
Mencit Galur BALB/C yang Diinduksi
Croton Oil
: PKM-PE
: Waliyyin Razan Qanit
: M0615047
: S1 Farmasi
: Universitas Sebelas Maret
: Jl. Selaawi Perum GMI Kav B21,
Tarogong Kaler Garut 44151
089671451582
: waliyyin.razan@gmail.com
: 2 orang
: Heru Sasongko, S.Farm., M.Sc., Apt.
: 0605118604
: Palur Wetan RT 03 RW 05 Mojolaban,
Sukoharjo (08562893838)
: Rp 12.000.000
: Rp -
: 5 bulan
Surakarta, 4 April 2018
20sadlask20129NI196606111991031
Ketua Pelaksana Kegiatan

Heru Sasongko, S.Farm.,M.Sc.,Apt. Waliyyin Razan Qanit

NIP. 1986120520140501 NIM. M0615047
Mengetahui,
Kepala Program Studi S1 Farmasi

Dr.rer.nat.Saptono Hadi S.Si, M.Si, Apt.

NIP. 197604032005011001

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 DAFTAR ISI
HALAMAN JUDUL........................................................................................i
HALAMAN PENGESAHAN..........................................................................ii
DAFTAR ISI.....................................................................................................iii
DAFTAR TABEL.............................................................................................iv
DAFTAR GAMBAR........................................................................................v
BAB I. PENDAHULUAN................................................................................1
1.1 Latar Belakang Masalah.......................................................................1
1.2 Rumusan Masalah.................................................................................2
1.3 Tujuan...................................................................................................2
1.4 Luaran...................................................................................................2
1.5 Manfaat.................................................................................................2
BAB II. TINJAUAN PUSTAKA......................................................................3
2.1 Ikan Sidat..............................................................................................3
2.2 Gamat....................................................................................................3
2.3 EPA dan DHA.......................................................................................3
2.4 Inflamasi...............................................................................................4
2.5 Krim......................................................................................................4
BAB III. METODE PENELITIAN..................................................................5
3.1 Tahap Preparasi Sampel Ikan Sidat & Gamat.......................................5
3.2 Tahap Ekstraksi Minyak Ikan Sidat & Ekstrak Gamat.........................5
3.3 Tahap Uji Kualitatif Dan Kuantitatif EPA DHA ..................................6
3.4 Formulasi Krim Kombinasi Minyak Ikan Sidat & Ekstrak Gamat......6
3.5 Uji Sifat Fisik Sediaan .........................................................................7
3.5.1. Organoleptis.................................................................................7
3.5.2. Tipe Emulsi .................................................................................7
3.5.3. Viskositas.....................................................................................7
3.5.4. pH................................................................................................7
3.5.5. Daya sebar...................................................................................7
3.6 Pengujian Krim Kombinasi Minyak Ikan Sidat & Ekstrak Gamat
Terhadap Hewan uji………………………………………………… 7
3.7 Analisis Data.........................................................................................8
BAB IV. BIAYA DAN JADWAL KEGIATAN................................................8
4.1 Anggaran Biaya....................................................................................8
4.2 Jadwal Kegiatan....................................................................................9
DAFTAR PUSTAKA........................................................................................9
LAMPIRAN.....................................................................................................11
Lampiran 1. Biodata Ketua, Anggota dan Dosen Pembimbing..................11

DAFTAR TABEL

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Tabel 1. Anggaran Biaya...................................................................................8
Tabel 2. Jadwal Kegiatan..................................................................................8

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 DAFTAR GAMBAR

Gambar 1. Diagram Alir Prosedur Penelitian ..................................................5