www.aamj.

in
AAMJ ISSN: 2395-4159
Anveshana Ayurveda Medical Journal Review Article

A critical review on therapeutic potential of

Dhanvayāsa (Fagonia cretica Linn.)
Naresh Kumar Ghodela 1 Suresh Kumar 2
Ved Prakash 3

Abstract

Dhanvayāsa is a small spiny undershrub known as Fagonia cretica Linn. (Family Zygophyl-
laceae). It is used by Ayurveda physicians as well as folklore used for management of different
diseased conditions. This plant is highlighted for compound formulations in classical texts of
Ayurveda. It possesses Tikta, Kaṣāya, Madhur rasa; Laghu, Sara guṇa; Śīta vīrya. In this review,
an endeavour has been made to explore the therapeutic utilities of Dhanvayāsa. Its compound
formulations are compiled from 7 different compendia and presented in a systemic manner.
Whole plant has been used as an ingredient of about 201 compound formulations. Maximum
formulations are found in Charak Samhita and Yogratnakar. The drug is used in 16 different
dosages forms, where Kvātha (Decoction), Ghrita (Ghee) and Cūrṇa (Powder) are found to be
maximum number. Majority of formulations containing Dhanvayāsa are indicated in Jvara (Fe-
ver) followed by Kāsa (respiratory disease), Arśa (Haemorrhoids) and Śvāsa.

Key words: Dhanvayāsa, formulations, Jvara, Kvātha.

1
PhD. Scholar, Dept. of Shalya Tantra, IPGT&RA, Gujarat Ayurved University, Jamnagar.
2
P.G. Scholar, Dept. of Shalya Tantra, National Institute of Ayurved, Jaipur. Rajasthan.
3
Assi. Prof., Dept. of Rog Nidan evum Vikriti Vigyan, SGCA&H, Tantia Hospital, Sriganganagar.
Rajasthan.

CORRESPONDING AUTHOR
Dr. Naresh Kumar Ghodela
PhD. Scholar
Department of Shalya Tantra,
IPGT&RA, Gujarat Ayurved University,
Jamnagar., (India).
http://aamj.in/wp-
Email: drghodela@gmail.com content/uploads/Volume3/Iss
ue1/AAMJ_1133_1141.pdf

AAMJ / Vol. 3 / Issue 1 / January – February 2017

 Naresh: A critical review on therapeutic potential of Dhanvayāsa (Fagonia cretica Linn.)
INTRODUCTION
A
yurveda deals with drugs of plant, animal, metal
and mineral origin. Among these maximum drugs
are of plant origin. [i] The classical Ayurveda text-
books elaborates protocols to study and understand the
occurrence of disease and validate the knowledge by
properties of drugs and their formulations for a diseased
condition.
Dhanvayāsa consists of dried whole plant of Fagonia
cretica Linn. syn. F. arabica Linn., F. bruguieri DC. (Fam-
ily. Zygophyllaceae)[ii]. It is a small spiny undershrub with
stiff branches often more or less prostrate. Leaves are op-
posite, 1-3 foliate, about 12 by 2.5mm, entire, linear or
elliptic, petiole very variable, 0.3cm long; stipules trans-
formed into sharp slender spines up to 1.2cm long, per-
sistent and continue growing long after the fall of the
leaves. Flowers are solitary and rose coloured or pinkish
violet in colour, arising from between the stipules. Fruits
are 5mm long, of 5, 1-seeded cocci. [iii] About thirty five
species are found in the entire Indian subcontinent and
is commonly known as ‘Dhamasa’. It is distributed
throughout the Mediterranean region of Africa, Afghani-
stan, India and Pakistan. It is well known in scientific lit-
terateur to be a therapeutic plant. It is used as diuretic,
analgesic, antipyretic, antihepatotoxic, antidysentric, an-
tidote, antiseptic, tonic, bitter, anti-asthmatic, stimulant,
stomachic and antitumor. [iv] Fagonia species have sapo-
nins, tannins, cardiac glycosides, triterpenoids, an-
thraquinines, alkaloids, coumarins and flavonoids. Phar-
macologically this plant possess Anti-inflammatory,
wound healing [v], Anti-allergic [vi], Antimicrobial [vii], Cy-
totoxic, antitumor [viii] and Neuroprotective activity. [ix]
Though the drug is used extensively in classics, recent
review shows that, literature regarding Dhanvayāsa, has
neither been explored nor presented in a systematic man-
ner. Hence, in this article an attempt has been made to
review the drug Dhanvayāsa from available classical lit-
erature and present in a systematic manner.
MATERIALS & METHODS
In this article, information of single and compound formu-
lations of Dhanvayāsa are compiled and critically ana-
lysed from Charaka Samhita [x], Sushruta Samhita [xi], Ash-
tanga Hridya [xii], Sharangadhara Samhita [xiii], Bha-
vaprakash Samhita [xiv],Yogaratnakar [xv] and Chakra-
dutta [xvi]. Obtained data are presented in precise manner
with regards to its synonyms, properties, action, various
compound formulations along with its dosage forms,
mode of administration, indications etc.[Table 2]
AAMJ / Vol. 3 / Issue 1 / January – February 2017
RESULTS & DISCUSSION
SYNONYMS:
In Ayurveda, traditionally various names known as Par-
yay (synonyms) have been attributed to a single plant can
be traced in texts known as Nighantus. About 21 syno-
nyms (Dhanvayāsa, Durālambha, Tāmramooli, Ka-
chhura, Durālabha, Dusparśa, Dhanvayāsaak, Sam-
udranta, Rodini, Gandhāri, Ananta, Kaṣāya,
Harivigraha, Tāmramoolika, Balapatra, Dhanvi,
Prabodhini, Sukshmadala, Virupa, Durlabha,
Duspragharsa) were attributed to Dhanvayāsa for de-
scribing its morphological and pharmacological charac-
ters by various classical texts of Ayurveda.
PHARMACOLOGICAL PROPERTIES
Dhanvayāsa has been attributed with Tikta, Kaṣāya,
Madhur rasa; Laghu, Sara guṇa; Śīta vīrya. Rajnighantu
mentioned Katu, amla rasa along with tikta and madhur
rasa and Ushna veerya; Pharmacological action in Pitta-
kapha-medo-mada roga, bhrama, Jvara, raktapitta.
FORMULATIONS
Formulations having Dhanvayāsa as an ingredient are
tabulated in [Table 1.] Analysis of compiled data from 7
different Samhita reveals that, about 201 single and com-
pound formulations of containing Dhanvayāsa as one of
the ingredients. Among them, maximum formulations
were used internally and only few formulations were
used externally. Among the ancient texts, maximum for-
mulations were mentioned in in Charaka Samhita (46),
Yogaratnakar (46) followed by and Astanga Hridaya
and Bhavprakash.
DOSAGE FORMS
Dhanvayāsa is being used in 16 different dosage forms
and among these maximum formulations were Kvātha
(70), Ghrita 28 and Cūrṇa (20). [Table 3] Kvātha form
suggests more water soluble constituents than other
forms. Kvātha is media to extract water soluble active
principles in the drug. While Ghrita is used as media for
absorption of lipid soluble contents to facilitate the
transport active principle across cell membrane.
DISEASE WISE INDICATIONS: [Table 4]
It is observed that, maximum number of formulations are
indicated in Jvara (Fever) followed by Kāsa, Arśa, Śvāsa.
External application of formulations indicated in lesions
of skin problems like Kuṣṭa.
1134
 Naresh: A critical review on therapeutic potential of Dhanvayāsa (Fagonia cretica Linn.)

Table 1: Total number of formulations found in classical texts.

SN Samhita No. of formulations

1 Charaka Samhita 46
2 Yogratnakar 46
3 Chakradutta 32
4 Ashtanga Hridaya 31
5 Bhavaprakasha Samhita 24
6 Sharangdhara Samhita 11
7 Sushruta Samhita 11
201

Table 2: Formulations of Dhanvayāsa from classical texts with their indications and mode of administration
1. SWARAS
Formulations Mode Indications Ref.
1 Dhanvayāsa Int. Mūtrāghāta A.H.
2 Duralabha + Shilajatu Int. Mūtrāghāta C.D.
3 Dusparśa Swaras Int. Mūtra vega Vighataj
C.D.
Udāvarta
4 Dusparśa Swaras Int. Mūtra avrodhajnya
B.P., Su.S.
Udāvarta
5 Virtarvadigana Kvātha + Duralabha Swaras Int. Sharkra-ashmari Y.R.
2. KVĀTHA
1 Astadashanga Kvātha Int. Sannipata Jvara Y.R., B.P.
2 Bharangyadi Kvātha Int. Jeerna Jvara Y.R.
3 Chandan, Balak, Musta, Bhunimba, Duralabha. Int. Pitta-Atisar Su.S.
4 Chandan, Indrayava, Patha, Duralabha, Int. Trishna
Y.R.
Guduchi, Balak, Lodhra, Pippali
5 Chandan, Kiratatikta, Dhanvayāsa, Nagar Int. Raktarśa Y.R.
6 Chandanadi Kvātha (Chandan, Kirat Tikta, Dhan- Int. Raktarśa
B.P.
vayāsa, Nagar, Darvi, Twak ,Ushira, Nimba)
7 Darvi, Duralabha, Bilva, Balak, Rakta-Chandan Int. Pitta-Atisar Su.S.
8 Dashmooladhya Astadashanga Kvātha Int. Sannipata Jvara C.D.
9 Devadarvyadi Kvātha Int. Sutika Roga, Prasuti-
(Devadaru, Vacha, Kuṣṭa, Pippali, Vish- doṣa
vabhaishjam, Bhunimba Katphal, Musta, Tikta,
B.P., Sha.
Dhanya, Haritaki, Gajkrishna, Dusparśa,
Gokshru, Dhanvyas, Vrihati, Ativisha, Chinna,
Karkata, Krishanajeerak)
10 Devdaryadi Kvātha Sutika Y.R.
11 Dhanvayāsa kvātha Int. Śītapitta Y.R.
12 Draksha, Kashmari, Kharjura, Patola, Arista, Int. Pitta- Visphota
B.P.
Vasa, Katuka, Dusparśa,
13 Drakshadhya Astadashang Kvātha Int. Jeerna Jvara B.P.
14 Drakshadi Kvātha (Draksha, Kashmari, Kharjura, Int. Pittaj Masurika
C.D.
Patol, Arista, Vasa, Laja, Amlak, Dusparśa)
15 Duralabha + Ghrita Int. Bhrama C.D.,Y.R., B.P.
16 Duralabha, Amrita, Musta, Nagar Int. Vātaaj Jvara A.H.
17 Duralabha, Parpat, Priyangu, Bhunimba, Vasa, Int. Trishna
Y.R.
Katurohini
18 Duralabhadi Kvātha Int. Pitta- Kapha Masu-
Y.R.
(Duralabha, Parpatak, Patol, Katurohini) rika
19 Duralabhadi Kvātha Int. Pitta-Jvara
(Duralabha, Parpat, Priyangu, Bhunimba, Vasa, C.D.
Katurohini)

AAMJ / Vol. 3 / Issue 1 / January – February 2017 1135

 Naresh: A critical review on therapeutic potential of Dhanvayāsa (Fagonia cretica Linn.)

20 Duralabhadi Kvātha (Duralabha, Parpatak, Int. Kaphaj Masurika

C.D.
Bhunimba, Katurohini)
21 Dusparśa, Musta Int. Doṣapachan Y.R.
22 Dusparśa, Parpatak, Megh, Kiratatikta Int. Pitta Jvara Y.R.
23 Dvipanchamool, Rasna, Darvi , Ushir, Duralabha, Int. Vātaaj Masurika ,
B.P.
Amrita, Dhanyak, Musta Vātaaj Visphota
24 Dvipanchamooladi Kvātha (Dvipanchmool, Int. Vātaaj Masurika
Rasna, Darvi, Usher, Duralabha, Amrit, Dhanyak, C.D.
Musta)
25 Dvipanchamulyadi Kvātha Int. Visphota Y.R.
26 Ghana, Ushira, Guduchi, Arlu, Dhanyaka, Du- Int. Raktasrava Before 3 rd
A.H.
ralabha, Parpata, Chandana, Ativisha, Bala Month
27 Guduchi, Ambudhar, Dhanvayāsa, Vishva, Int. Vātaaj Jvara Y.R.
28 Haritkyadi Kvātha Int. Mūtrakrichha
(Haritaki, Duralabha, Kritamal, Gokshura, Pa- Sha., C.D., B.P.
shanbheda)
29 Haritkyadi Kvātha Int. Mūtrakrichha Y.R.
30 Jambvadi Kvātha Int. Chhardi C.D.
31 Jatyadi Kaṣāya Int. Jvara
C.S.
(Jati, Aamalak, Musta, Dhanvayāsa)
32 Kiratatikadi Kvātha Int. Visarpa C.S.
33 Kiratatiktak, Shunthi, Dhanvayāsa, Kuchandan, Int. Arśa, Raktasrava
A.H.
Darvi, Nimba.
34 Maharasnadi Kvātha Int. Vātaavyadhi Sha.
35 Maharasnadi Kvātha Int. Sravanga Kamp Y.R.
36 Maharasnadi Kvātha Int. Vātaaroga B.P.
37 Musta, Parpatak, Shunthi, Guduchi, Duralabha Int. Kapha-Vātaa Jvara Y.R.
38 Musta, Vasa, Shunthi, Dhanvayāsa Int. Kaphaj Jvara Y.R.
39 Mustadhya Astadashanga Kwata Int. Sannipata Jvara C.D.
40 Mustadi Kvātha Int. Vātaa-Shleshma
C.D.
(Musta, Parpata, Shunthi, Guduchi, Duralabha ) Jvara
41 Nimba, Parpatak, Patha, Patol, Chandan Dvya, Int. Pittaj- Masurika
B.P.
Ushira, Katuka, Dhatri, Vasa, Duralabha,
42 Nimbadi Kvātha Int. Pitta- Rakta Masurika,
(Nimba, Parpatak, Patha, Patol, Katurohini, Vasa, Visarpa, Y.R., B.P.
Duralabha, Dhatri, Chandan Dvaya)
43 Nimbadi Kvātha (Nimba, Parpatak, Patha, Patol, Int. Tridoshj Masurika
Katurohini, Vasa, Duralabha, Dhatri, Ushira, C.D.
Chandan Dvya)
44 Parpatadi Kvātha (Parpata,Vasa,Tikta,Kirat, Int. Pitta-Jvara
Sha., B.P.
Dhanvayāsaa,Priyangu,Sharkara )
45 Parpatak, Dhanvayāsa, Vasa, Bhustrana, Kutaki, Int. Mukhagata Rak-
Y.R.
Phalini, Sharkara tsrava
46 Pashanabhedadi Kvātha Int. Sannirudhha Mūtra Y.R.
47 Patha, Sirisha, Dusparśa, Murva, Kinshuka, Tin- Int. Hastimeha
C.D.
duka, Kapithaa
48 Patha, Vidanga, Arjuna, Dhanvayāsa Int. Kaphaj Prameha Y.R.
49 Patoladi Kvātha Int. Raktaj Masurika,
(Patol, Kundali, Musta, Vasa, Dhanvayāsa, Vishota-Jvara Y.R., C.D.
Bhunimba, Katuka, Parpata)
50 Patoladi Kvātha Dvitiya Int. Visarpa C.D.
51 Pipplayadi Kvātha Int. Vātaa-Shleshma
(Pipali, Piplimool,Chavya,Chitrak, Nagar, Saniipataj- Jvara
Vacha,Ativisha,Ajaji,Patha,Vātasaka,Re-
nuk,Kirattiktak,Murva,Sarśapa,Mari- Sha.
cha,Katuka,Pushkar, Bharngi, Vidanga, Kar-
katavhyam, Arkamool, Vrihatsinhi,Shreyasi,Du-
ralabha,Dipyaka,Ajmoda, Shukanasa, Hingu,)

AAMJ / Vol. 3 / Issue 1 / January – February 2017 1136

 Naresh: A critical review on therapeutic potential of Dhanvayāsa (Fagonia cretica Linn.)

52 Pushkar, Eranda Mool, Yava, Dhanvayāsa Int. Gulma A.H.

53 Rasnadwadasha Kvātha Int. Amavātaa Y.R.
54 Rohish, Dhanvayāsa, Vasa, Parpat, Gandhalata, Int. Kshataj Sthivi
B.P.
Katuka,
55 Sariva, Ativisa, Kuṣṭa, Purahva, Duralabha, Int. Kapha Jvara
Su.S.
Musta
56 Shatyadi Kvātha Int. Saniipata Jvara C.D.
57 Sringi, Dhanvayāsa, Pushkar, Jata, Bharngi, Sati, Int. Abhinyasa Jvara
Y.R.
Sinhika
58 Tamra + Duralabha Kvātha Int. Bhrama B.P.
59 Tikta, Vrisha, Ushira, Trayanti, Triphla, Amrita, Int. Kapha-Pitta Jvara
A.H.
Patola, Ativisha, Nimba, Murva, Dhanvayāsa
60 Tinduk, Kapithha, Sirisha, Palash, Patha, Murva, Int. Hasti Meha
Su.S.
Dusparśa
61 Trikantak, Aragwadha, Darbha, Kasha, Du- Int. Mūtrakrichha
B.P.
ralabha, Parvātabheda, Pathya
62 Trikantakadi Kvātha Int. Ashmari Y.R.
63 Trikantakadi Kvātha Int. Mūtrakrichha
(Trikantaka, Aragwadha, Darbha, Kasha,Du- C.D.
ralabha, Parvātabeda, Pathya.)
64 Trivrata, Duralabha, , Musta, Sharkara, Udi- Int. Virechana In Sharad
Sha.
chaya, Chandana, Draksha, Yasti Ritu
65 Vātasak, Aaragwadha, Patha, Sadgrantha, Ka- Int. Jvara
turohini, Murva, Ativisa, Nimba, Patol, Dhan-
C.S.
vayāsa, Vacha, Musta, Ushir,Madhuk, Triphla,
Bala
66 Vrahatyadi Gana Kvātha Int. Sannipata Jvara C.D.
67 Vrahtyadi Kvātha (Vrahti, Pushkar, Bharngi, Sati, Int. Sannipat Jvara
B.P.
Sringi, Duralabha, Vātasak, Patol , Katurohini )
68 Vrahtyadi Varga Kvātha Int. Sannipat Jvara
C.S.
Nashak
69 Vrihatpippalaydi Kvātha Int. Vātaa-Kapha Jvara B.P.
70 Vrisha, Gangeyi, Shringaber, Duralabha Int. Kaphaj Jvara A.H.
3. ŚĪTA /HIMA
1 Darvi, Guduchi, Triphla, Draksha, Jatipallava, Gandush Mukhapaka
Sha.
Dhanvayāsa
2 Draksha, Parpatak, Shunthi, Guduchi, Dhan- Int. Trishna, Visarpa
C.S.
vayāsa
3 Duralabha, Parpatak, Guduchi, Shunthi Int. Trishna, Visarpa Y.R., A.H.
4 Jati, Amlaka, Musta, Dhanvayāsa Int. Sarva-Jvara A.H.
5 Kantakateri, Hribera, Bilva, Duralabha Int. Pittaj Atisar A.H.
6 Musta, Parpata, Shunthi, Dusparśa Int. Jvara A.H.
7 Nagar, Parpatak, Duralabha Int. Jvara, Deepan, Pa-
C.S.
chan
8 Satyadi Varga Kvātha Int. Sannipat Jvara C.S.
9 Sunthi, Sthira, Udichya, Dusparśa Int. Kaphaj Madatyay A.H.
10 Vātasak, Aaragwadha, Patha, Sadgrantha, Ka- Int. Jvara
turohini, Murva, Ativisa, Nimba, Patol, Dhan-
C.S.
vayāsa, Vacha, Musta, Ushir,Madhuk, Triphla,
Bala
4. CŪRṆA
1 Abhaya, Pipalli, Draksha, Sita, Dhanvayāsa. Int. Kantha Daha. B.P.
2 Darvi, Kiratatikta, Musta, Dusparśa Int. Raktarśa C.S.
3 Dashastanga Cūrṇa Int. Jeerna Jvara Y.R.
4 Devadaru, Sati, Rasna, Karkati, Duralabha Int. Kaphaj Kāsa
C.S.

AAMJ / Vol. 3 / Issue 1 / January – February 2017 1137

 Naresh: A critical review on therapeutic potential of Dhanvayāsa (Fagonia cretica Linn.)

5 Duralabha Int. Kaphaj Chhardi A.H., C.S.,

C.D.
6 Duralabha, Shati, Draksha, Sringber, Sitopala, Int. Kāsa
C.S., A.H.
Karkatsringi
7 Duralabhadi Cūrṇa Int. Rajyakshama C.S.
8 Dusparśa, Pippali, Musta, Bharngi, Karkatki, Sati. Int. Kāsa C.S.
9 Dusparśa, Patha Int. Arśa Ruja A.H., C.S.
10 Dusparśa, Pipali, Musta, Bhargi, Karkatki, Shati Int. Kāsa A.H.
11 Kiratatiktadi Cūrṇa Int. Raktapitta C.S.
12 Pathadi Cūrṇa Int Hridda-roga C.D.
13 Poskaradi Cūrṇa Int. Kāsa Y.R.
14 Puskar, Ativisha, Sringi, Magadhi, Dhanvayāsa Int Kāsa C.D.
15 Saindhava, Pippali, Bharngi, Sringaber, Du- Int. Kāsa
C.S.
ralabha
16 Shyama, Trivratta, Duralabha, Hastipippali, Int. Virechana
A.H.
Vastak, Nilini, Katuka, Musta, Shrestha
17 Sudarśana Cūrṇa Int. Jvara Sha.
18 Trivratta, Duralabha, Musta, Sharkar, Udichya, Int. Virechana
C.S.
Chandan, Yastimadhu, Satla
19 Trivratta, Shyama, Duralabha, Vātasak, Hastipip- Int. Virechana
C.S.
pali, Nilini, Triphla, Musta, Katuka
20 Vachadi Cūrṇa Int. Grahni C.S.
5. LEHA
1 Abhayadhya Leha Int. Kantha Daha,
Y.R.
(Abhaya, Pippali, Draksha, Sita, Dhanvayāsa) Shlesham- Amlapitta
2 Chitrakadi Leha Int. Kāsa, Hridda-roga C.S.
3 Devdaryadi Leha Int. Kāsa
A.H.
(Devdaru, Shati, Rasna,Karkataka,Duralabha)
4 Draksha, Haritaki, Musta, Karkatak, Duralabha Int. Śvāsaa
Y.R.

5 Drakshadhya Leha Int. Śvāsa

(Draksha, Haritaki, Krishna, Karkatak, Du- Su.S.
ralabha)
6 Duralabha, Kana, Draksha, Pathya Int. Kāsa, Śvāsaa Y.R.
7 Duralabha, Pippali, Kutki, Haritaki Int. Śvāsa, Kāsa Su.S.
8 Durnamadijit Avleha Int. Gulma A.H.
9 Jeevantyadi Leha Int. Kāsa C.S.
10 Kantakaryavleha Int. Kāsa Y.R.
11 Kantakaryavleha Int. Hikka, Śvāsa Sha., B.P.
12 Kharjura, Pippli, Draksha, Pathya, Sringi, Du- Int. Kāsa, Śvāsaa, Parsh-
C.S.
ralabha vashool
13 Visvadi leha Int Vātaik Kāsa C.D.
6. GHRITA
1 Baladhya Ghrita Int. Rajyakshma C.D.
2 Baladi Ghrita Int. Jvara C.S., Y.R.
3 Chavikadi Ghrita Int. Kāsa A.H.
4 Duralabhadi Ghrita Int. Jvara, Daha, Bhrama C.S.
5 Dwipanchamulyadi Ghrita Int. Kshaya Kāsa C.S.
6 Gokshuradhya Ghrita Int. Jvara, Daha Y.R.
7 Jeevantyaadi Ghrita Int. Rajyakshma C.D., C.S.,
Y.R., A.H.
8 Kalyanakam Ghrita Int. Bala Roga C.D.
9 Kantakari Ghrita Int. Kāsa A.H., C.S., Y.R.

AAMJ / Vol. 3 / Issue 1 / January – February 2017 1138

 Naresh: A critical review on therapeutic potential of Dhanvayāsa (Fagonia cretica Linn.)

10 Katukadhya Ghrita Int. Raktapitta, Jvara,

C.S.
Daha,Visphotak
11 Mahamayura Ghrita Int. Siroroga C.S.
12 Mahapanchagavya Ghrita Int. Apasmar A.H., C.S.
13 Mahatikta Ghrita Int. Kuṣṭa C.D.
14 Mahatiktak Ghrita Int. Kuṣṭa Sha., A.H.,
Su.S., C.S.
15 Meda, Vidari, Kakoli, Swayamgupta, Bala, Int. Pittaj Kāsa
Sharkara, Jeevak, Mudagparni, Mashaparni, Du- A.H.
ralabha.
16 Pathadi Ghrita Int. Kāsa Su.S.
17 Patoladhya Ghrita Int. Mukharoga Y.R.
18 Patoladhya Ghrita Int. Netra Roga C.D.
19 Patoladi Ghrita Int. Netra roga Su.S.
20 Somraji Ghrita Int. Shwitra B.P.
21 Tiktak Ghrita Int. Kuṣṭa A.H.
22 Tiktasatapala Ghrita Int. Kuṣṭa, Y.R., C.S., C.D.
23 Trayamanadi Ghrita Int. Gulma Y.R., C.S., C.D.
24 Triphladi Ghrita Int. Visarpa, Jvara Su.S.
25 Vasadi Ghrita Int. Jeerna Jvara C.S.
26 Vidari Ghrita Int. Mūtrāghāta B.P.
27 Vidradhradyadi Nashak Ghrita Int. Vidhridhi A.H.
28 Vrahat-Kantakari Ghrita Int. Kāsa, Hikka, Śvāsaa C.D.
7. TAILA
1 Kuṣṭadi Taila Ext. Kuṣṭa C.S.
2 Mahavishagarbha Taila Ext. Sandhanartha, Y.R.
Gridhrasi
3 Rasnapootik Taila Int., Ext. Aakshepak, Y.R.
Ghridhrasi
8. ĀSAVA
1 Duralabhāsava Int. Grahni, Pandu, Rak- C.S.
tapitta
2 Sharkarāsava Int. Arśa, Grahni Y.R.
3 Ushirāsava Int. Raktapitta, Kuṣṭa, Sha.
Prameha, Arśa.
9. ARISTA
1 Duralabhadhyarista Int. Arśa A.H.
2 Dvitiya Phalarista Int. Arśa, Grahni Doṣa C.S.
10. PEYA
1 Bilva, Daruharidra, Twak, Hribera, Duralabha Int. Pitta-Atisar C.S.
2 Hribera, Dhataki, Bilva, Duralabha Int. Raktapitta A.H.
3 Katphala, Nagar, Patha, Jambu-Amra Asthi, Du- Int. Pitta-Atisar C.S.
ralabha
4 Vyaghri, Dusparśa, Gokshur Tidoṣaj Jvara B.P.
11. YUSHA
1 Nidighdikadi Yusha Int. Hikka, Śvāsa C.S.
2 Shigru, Vartak, Kāsaghna, Vrisha, Nimba-Kulak- Int. Hikka-Śvāsa A.H.
Vrihati-Matulunga Pallava, Vyaghri, Duralabha,
Shringi, Bilva, Trikantak, Amrita, Agni, Kullatha.
12. YAVAGU
1 Dhataki, Dhanvayāsa, Ambu, Bilva Int. Raktapitta C.S.
2 Vyaghri, Dusparśa, Gokshur Int. Tridoṣaj jvara C.D.

AAMJ / Vol. 3 / Issue 1 / January – February 2017 1139

 Naresh: A critical review on therapeutic potential of Dhanvayāsa (Fagonia cretica Linn.)

13. GUTIKA
1 Astadashanga Lauha Int. Pandu, Halimak, B.P.
Shotha, Prameha
2 Dwatrinshko Guggulu Int. Maha Jvara, Y.R.
Gridhrasi
3 Khadiradi Gutika Int. Mukharoga A.H.
4 Shadaasiti Guggulu Int. Yakshma, Vātaaroga Y.R.
14. AALEPA
1 Kuṣṭadi Yoga Ext. Kuṣṭagna C.S.
2 Kuṣṭadi Yoga Ext. Sidhma Kuṣṭa Y.R.
(Kuṣṭa, Mulak Beej, Priyangu, Sarśap, Du-
ralabha)
15. KSHARA
1 Chaturtha Kshara Int. Grahni, Shotha, C.S.
Arśa.
2 Duralabhadi Kshara Int. Grahnibal Vardhan C.S.
16. PANIYYA
1 Dusparśa, Musta Int. Kaphaj Madatyaya C.S.

Abbreviations: C.S. – Charaka Samhita, Y.R. – 7 Visarpa 06

Yogratnakara, B.P. - Bhavprakasha, C.D. - Chakradutta, 8 Raktapitta 06
Su.S. - Sushruta Samhita, A.H. - Astanga Hridaya, Sha. 9 Grahni 06
– Sharangdhara; Int. - Internal, Ext. - External 10 Prameha 05
11 Mūtrakrichha 05
12 Mūtrāghāta 05
Table 3: Different dosage forms of Dhanvayāsa
13 Daha 05
Sr.No. Formulations Number
14 Atisar 05
1 Kvātha 70
15 Visphota 04
2 Ghrita 28
16 Trishna 04
3 Cūrṇa 20
17 Rajyakshma 04
4 Avleha 13
18 Hikka 04
5 Śīta/ Hima 10
19 Vātaavyadhi 03
6 Swaras 05
20 Raktasrava 03
7 Vātai 04
21 Gulma 03
8 Peya 04
22 Bhrama 03
9 Taila 03
23 Sutika Roga 02
10 Āsava 03
24 Pandu 02
11 Arista 02
25 Netra Roga 02
12 Yūsha 02
26 Mukha Roga 02
13 Yavagu 02
27 Madatyay 02
14 Aalepa 02
28 Hridda-Roga 02
15 Kshara 02
29 Gridhrisi 02
16 Paaniya 01
30 Chhardi 02
31 Ashmari 02
Table 4: Different disease condition and number of 32 Vidhradhi 01
formulations 33 Siro Roga 01
Sr.No. Disease Formulations 34 Shwitra 01
1 Jvara 42 35 Śītapitta 01
2 Kāsa 21 36 Mukhapaka 01
3 Arśa 10 37 Apasmar 01
4 Śvāsa 09 38 Amvātaa 01
5 Masurika 09
6 Kuṣṭa 08

AAMJ / Vol. 3 / Issue 1 / January – February 2017 1140

 Naresh: A critical review on therapeutic potential of Dhanvayāsa (Fagonia cretica Linn.)
CONCLUSION
Dhanvayāsa an undershrub; is indicated for Jvara, rak-
tapitta, vātavyadi, dusta- rakta janya rogas (visarpa,
kuṣṭa, kandu), mūtragat vikar (mūtraghat, mūtrakrichha),
kāsa, śvāsa, hikka, chhardi and raktarśa etc. It is used
in almost 201 different formulations described in ancient
literatures in various doses forms either externally or in-
ternally. This review claim that this drug can be consid-
ered as an important medicine for Ayurveda practicing.
This drug is already proved as anti-inflammatory, anal-
gesic, antipyretic, anti-allergic, antimicrobial, antioxi-
dant activity and can be used for various pharmacologi-
cal action. There is a need to conduct clinical trials for
intensive scientific validation on various claimed disease
conditions.
ΛΛΛΛ
REFERENCES
i. Anonymous. Ayurvedic Formulary of India. E-book, 2nd
Edn. Delhi: Published by the Controller of Publication.
2000. Part I. Single Drugs – List of Plant Origin
ii. The Ayurvedic Pharmacopoeia of India Part- I Volume – V.
Government of India. Page. No. 30
iii. Kirtikar K.R. and Basu B.D., Indian Medicinal Plants, Ed-
ited by E. Blatter, J.F. Caius and K.S. Mhaskar, Vol. 1,Deh-
radun : International book distributors; 1994.p.427.
iv. B. Sajid, E. Alia, K. Rizwana, S. Uzma, Alamgeer andM.
Hafiz .Phytochemical screening and antimicrobial activity
of Fagonia cretica plant extracts against selected mi-
crobes. Journal of Pharmacy Research. 2011.4; 962.
v. Saleh IA, Hasan SY, Aftab A. Anti-inflammantory and
wound healing activity of Fagonia schweinfurthi alcoholic
AAMJ / Vol. 3 / Issue 1 / January – February 2017
extract herbal gel on albino rats. African Journal of Phar-
macy and Pharmacology 2011; 5(17): 1996-2001.
vi. Yahya AL, Abdulaziz M. Fagonia bruguieri freeze dried
extract as anti-allergic treatment. WIPO Patent Application
WO/2007/072100.
vii. Anjum MI, Ahmed E, Jabbar A, Malik A, Ashraf M, Mo-
azzam M, et al. Antimicrobial constituents from Fagonia
cretica 2007; 29(6):634-639.
viii. Lam M, Carmichael AR, Griffiths HR. An aqueous extract
of Fagonia cretica induces DNA damage, cell cycle arrest
and apoptosis in breast cancer cells via FOXO3a and p53
expression. Plosone 2012; 7(6).
ix. Rawal AK, Muddeshwar MG, Biswas SK. Rubia cordifolia,
Fagonia cretica linn and Tinospora cordifolia exert neuro-
protection by modulating the antioxidant system in rat hip-
pocampal slices subjected to oxygen glucose depriva-
tion.BMC Complementary and Alternative Medicine
2004, 4: 11.
x. Agnivesha, Charaka, Dridhabala, Charaka samhita, ed-
ited by Dr. Brahmanand Tripatii, Chaukhambha Surabha-
rati Prakashana, Varanasi. Reprint 2007.
xi. Sushruta samhita, edited by Kaviraj Ambikadutta Shastri,
Chaukhamba Sanskrit sansthan, Varanasi. Reprint 2006.
xii. Vagabhat, Astanga Hridya,With Vidyotini Hindi commen-
tary, edited by Vaidya Sri Yadunandana Upadhyaya,
Chowkhamba Sanskrit Series office, Varanasi, Reprint
1970.
xiii. Sharangdhar Samhita, edited by Pt. Durgadutta Sastri,
with Tatvadipika Hindi commentary, Chaukhamba vidya
bhavan, Varanasi. Reprint 2002.
xiv. Bhavmishra, Bhavaprakasa, edited by Pandit Sri Brahma
Sankara Misra with the Vidyotani Hindi Commentary,
Chaukhambha Sanskrit Sansthan, Varanasi, 7th Edition
2000.
xv. Yogaratnakara, edited by Bhisagratna Brahmasankar
Sastri with Vidyotini Hindi Commentary, Chaukhamba pra-
kashan, Varanasi, reprint 2010.
xvi. Sri Chakrapanidatta, Chakradatta, edited by Ramanath
Dwivedy, with Vaidayaprabha Hindi commentary, Chau-
khambha Sanskrit bhawan, Varanasi. Reprint 2015.
Source of Support: Nil.
Conflict of Interest: None declared
How to cite this article: Naresh: A critical review on thera-
peutic potential of Dhanvayāsa (Fagonia cretica Linn.).
AAMJ 2017; 1:1133 – 1141.
ΛΛΛΛ
1141