HPV: Human Papillomavirus

The viruses and the vaccines –

A Risk-Benefit Analysis

Marcella Piper-Terry, M.S.

 What are human papillomaviruses?
• A group of more than 200 related viruses

• More than 40 types of HPV can be spread through direct sexual contact
• Vaginal, anal, oral, skin-to-skin

• Sexually-transmitted HPV viruses are classified as Low-Risk or High-Risk

• LR-HPV types are associated with warts and upper respiratory infections

• 15-18 HR-HPV types are associated with certain cancers

• Cervical cancer (women)
• Anal cancer (men and women)
• Vaginal and vulvar cancers (women)
Source: National Cancer Institute, CDC
 How prevalent is HPV infection?
• Most common sexually-transmitted infections in the United States

• 14 million newly acquired genital HPV infections each year in the U.S.

• 80-90% of all sexually active women and men will acquire at least one
HPV infection during their lifetime

Source: National Cancer Institute, CDC

Source: National Cancer Institute, CDC
 • There are 14 million new genital HPV cases each year in the U.S.
• There are 12,900 new cases of cervical cancer each year in the U.S.
Sources: NIH, CDC

12,900 is 0.09% of 14,000,000. That translates to a case ratio of 1 in 9,000.

That means about one case of every 9,000 new cases of HPV infection is associated with
cervical cancer.
That ALSO means that the other 8,999 new cases of HPV infection are NOT associated with
cervical cancer.
Source: National Cancer Institute, CDC
 Watch this video about cervical cancer
from the National Cancer Institute:
www.TinyURL.com/CervicalCancerVideo

Then come back to this presentation and let’s

discuss the information presented.
 The dark blue areas represent the highest number of
newly diagnosed cases of cervical cancer.

Notice how newly diagnosed cervical cancer cases decreased from 1995-2004.
Gardasil – the HPV vaccine used in the United States had NOTHING to do with this.

FACT: GARDASIL VACCINE WAS LICENSED IN 2006.

Source: National Cancer Institute
 “A simple Pap test can find abnormal cervical cells before they become cancer.”
As a result of increased screening programs, new diagnoses of cervical cancer…
• Decreased by more than 50% overall between 1975-2010.
• Decreased by more than 65% in women over the age of 50 years.

Groups still at increased risk include:

• Black Women in The South
• Hispanic Women along the U.S./Mexico Border
• White Women in Appalachia
• Native American Women
• Asian American Women
• Alaska Natives
• Pacific Islanders

Increased risk is “due at least in part to lack of access to screening programs.”

Source: National Cancer Institute
Watch this Gardasil commercial from Merck:
www.TinyURL.com/HPVoneless

Then come back to this presentation

and let’s discuss…
Did you notice how heavily Merck targeted African American, Hispanic, and Asian women?
These are the very groups identified by the National Cancer Institute as being at higher risk
of newly diagnosed cases of cervical cancer – not because of a lack of the vaccine… because
of inequality when it comes to healthcare and access to pap screens.
This is psychological manipulation and fear mongering for profit.
 HPV Vaccines: Cervarix, Gardasil, and Gardasil9
• Cervarix - licensed in 2009, for protection from HPV 16 & 18
• Gardasil - licensed in 2006, for protection from HPV 6, 11, 16 & 18
• Gardasil 9 - licensed in 2015, for protection from HPV 6, 11, 16, 18, 31, 33, 45, 52, and 58

Gardasil 9 is currently most widely used in the United States,

and is recommended for boys and girls as young as 9 years of age.
Vaccine Information Statement (VIS) for Gardasil 9
Who is Dr. Diane Harper?

TinyURL.com/DrHarperHuffpo
TinyURL.com/DrHarperHuffpo
More from Dr. Diane Harper…

TinyURL.com/DrHarperHuffpo
TinyURL.com/DrHarperHuffpo
TinyURL.com/DrHarperHuffpo
Please watch this video and hear from the young women
(and the families, in the cases of those who have died) about
how Gardasil vaccine took their lives.
www.tinyURL.com/NotACoincidence

TInyURL.com/NotACoincidence
VRBPAC: Vaccines and Related Biological Products Advisory Committee
Part of the U.S. Food and Drug Administration (FDA) that conducts meetings and reviews information submitted
by vaccine manufacturers regarding safety and efficacy in clinical trials.
TinyURL.com/GardasilVRBPAC
 What the heck is a “virus-like particle?”

TinyURL.com/HPVvlp

CIN: Cervical Intraepithelial Neoplasia 2/3: “Abnormal cells are found on the surface of the cervix. Cervical intraepithelial
neoplasia grade 2/3 is usually caused by certain types of human papillomavirus (HPV) and is found when a cervical biopsy
is done. Cervical intraepithelial neoplasia grade 2/3 has features of CIN 2 and CIN 3. It is not cancer, but may become cancer
and spread to nearby normal tissue if not treated. Treatment for cervical intraepithelial neoplasia grade 2/3 may include
cryotherapy, laser therapy, loop electrosurgical procedure (LEEP), or cone biopsy to remove or destroy the abnormal tissue.”
TinyURL.com/GardasilVRBPAC
Women and girls who were already infected with HPV strains covered in the vaccine had
a 45% increased incidence of pre-cancerous lesions following vaccination with Gardasil.

TinyURL.com/GardasilVRBPAC
Given that vaccination increases the incidence of pre-cancerous lesions in those previously
infected with HPV, it is important to determine who is HPV+ prior to vaccination.
This is not being done.
It has been known since at least 1997 that HPV can be transmitted from mother to infant.

TinyURL.com/HPVmombaby
TinyURL.com/HPVmombaby
“The Finnish HPV Family Study was designed to evaluate the natural history of HPV infections
of the infant, as well as the transmission of HPV between the parents and the infant. The
present report is focused on the dynamics and risk factors associated with the acquisition of
HR HPV in infants.”
TinyURL.com/HPVparentbaby
TinyURL.com/HPVparentbaby
TinyURL.com/GardasilVRBPAC
Only 28.2 percent of women with CIN2 or CIN3 confirmed by biopsy were infected
exclusively by HPV 16 or 18, a finding that places in doubt the degree of protection
afforded by HPV vaccination.
 Evidence of viral shift and replacement…

Among the findings:

• HPV+ women aged 16-22, who were more likely to be protected against vaccine-strains of HPV, had
increased rates of infection with other strains of High-Risk HPV, compared to older women who
had not been vaccinated
• Evidence of increased virulence of HPV strains not included in the vaccines, with strains previously
considered “Low-Risk HPV” now being classified as “High-Risk HPV”
TinyURL.com/HPVshift
The Clinical Trials for Gardasil…

Merck, the CDC, and many pediatricians

Claim that Gardasil is “safe” and
“effective” at preventing cancer.

What does the evidence really show?

TinyURL.com/HPVclinicaltrials
Table 1, part 1
Characteristics of 6 randomized
controlled trials (and 3 follow-up
studies) of human papillomavirus
(HPV) vaccination included in the
systematic review

TinyURL.com/HPVclinicaltrials
First issue: Ethnic background. Study subjects were overwhelmingly white. Risk factors for chronic HPV infection include
Hispanic or African American race. White women, and those with higher socio-economic status are the very women
who are most likely to clear the virus on their own within 6 months to 2 years.

Second issue: Lifetime number of sexual partners. Participants were excluded if they had more than 6 sexual partners;
in three of the studies, the median number of sexual partners was 2 or less. Risk factors for chronic HPV infection
include higher number of lifetime sexual partners. Women who have 6 or less partners, and certainly women who have
had 2 or less partners are not among those who would be considered to be at higher risk for long-term HPV infection.

TinyURL.com/HPVclinicaltrials
Table 1, part 2
Characteristics of 6 randomized
controlled trials (and 3 follow-up
studies) of human papillomavirus
(HPV) vaccination included in the
systematic review

TinyURL.com/HPVclinicaltrials
Third issue: There were no true Control or Placebo groups. Five out of six
of the "Placebo" groups were given the adjuvant (aluminum, 225-500 mcg).
The sixth study used another vaccine (Hepatitis A vaccine) as the "Placebo."
The hepatitis A vaccine used (Havrix) contains 250 mcg. of aluminum.
TinyURL.com/HPVclinicaltrials
Merck
Placebo (definition): An inert or innocuous substance used especially in
controlled experiments testing the efficacy of another substance (such as a drug)

TinyURL.com/HPVclinicaltrials
 From Merck’s manufacturer’s insert for Gardasil:

29,323 / 40 = 733
In the clinical trials for Gardasil, 1 out of every 733 subjects DIED.
These were healthy adolescents and young adults, who had been
screened for preexisting conditions, prior to entering the trials.
TinyURL.com/GardasilInsert
From Merck’s manufacturer’s insert for Gardasil:

TinyURL.com/GardasilInsert
From Merck’s manufacturer’s insert for Gardasil9:

TinyURL.com/Gardasil9Insert
 From Merck’s manufacturer’s insert for Gardasil9:

…recipients reported new medical conditions potentially

indicative of systemic autoimmune disorders…
At 2.2% - 3.3%, that’s 22,000 – 33,000 per million. Not “one in a million.”
There are 4 million children born in the United States each year.
If just ONE birth cohort (all 11 year olds) were vaccinated with Gardasil or Gardasil 9,
we could expect 88,000 – 132,000 “new medical conditions potentially indicative of systemic
autoimmune disorders.”
That’s from their own data. How can they continue to claim this vaccine is safe?
TinyURL.com/Gardasil9Insert
Serious Adverse Events are “One in a million?”

22,000 in one million for Gardasil 9

33,000 in one million for Gardasil

What does 2.2 – 3.3% look like for one birth cohort in the United States?

88,000 – 132,000
How can they continue to deny the damage,
when they found it in their own clinical trials?
An article published in the Journal of the American Medical Association (JAMA) estimated that serious adverse
reactions to any medical product or device (including vaccines) are grossly under-reported, with as little as
1-10% of such reactions ever reported.
An article published in the Journal of the American Medical Association (JAMA) estimated that serious adverse
reactions to any medical product or device (including vaccines) are grossly under-reported, with as little as
1-10% of such reactions ever reported.
 Graph from Sanevax.org

Maroon bars = HPV vaccines (Gardasil, Cervarix) Blue bars = ALL other vaccines combined
SANE Vax Inc. Concerns
• Does the aluminum adjuvant become the carrier for HPV DNA
causing said DNA to remain in the blood and/or organs for an
extended length of time?

• Since viral DNA cannot replicate by itself (it needs a host cell)
what happens if genetically engineered viral DNA enters a
human host cell?

• How will this now ‘genetically-engineered cell’ replicate? Will

it mutate the host cell leading towards cancer?

• How will genetically engineered cells affect the reproductive

health of future generations?

• How does the immune system react to the detection of a

combination viral DNA and human DNA in what was once
a ‘normal’ cell? Will the immune system fight the now
genetically engineered human cell?

TinyURL.com/SanevaxHPVDNA
TinyURL.com/DrSuzanneHPV

TinyURL.com/DrSuzanneAAHS TinyURL.com/vaxxedTVgardasil
A class action lawsuit has been filed in
Colombia, on behalf of more than 700
girls and women whose health has been
negatively affected by Gardasil.

The group is suing Merck Sharp and Dohme

for damages in the amount of 490 Billion
Pesos ($30.5 million, U.S.).

TinyURL.com/GardasilColombia
TinyURL.com/GardasilJapan
Why isn’t the United States government looking into the problems with Gardasil/Gardasil9?
 The National Cancer Institute is part of
The National Institutes of Health…
A United States Government Agency.

TinyURL.com/NCIpatentHPVvax
The United States government and Merck are business partners.

TinyURL.com/NIHmerckpartners
Merck continues to use guilt and psychological
manipulation to increase sales of Gardasil with their
2016 commercial asking, “Mom, Dad… Did you know?”

Responsible parents want to do right by their children.

They have no idea the CDC and the U.S. government
have financial incentives to recommend Gardasil.

TinyURL.com/MerckHPVcommercial
Merck’s new ad shaming and blaming parents first aired on June 28, 2016, running on all
major networks, including during the Summer Olympics, maximizing the impact of
advertising dollars.
It paid off.
The cost of Gardasil 9 for use in the private sector is currently $217.11 per dose. (2019)
Of the Top 5 Vaccine Products Worldwide, Gardasil ranks 2nd,
with projected sales at $2.5 Billion by 2020

Remember… Merck isn’t the only one benefitting from this surge in sales. The U.S. government also benefits
financially from the sale of Gardasil. Could this be a factor in why our elected officials and their agencies are
turning a blind eye?
Source: Evaluate Pharma: http://info.evaluategroup.com/rs/607-YGS-364/images/wp15.pdf
 Recap: Take-away points for HPV & Gardasil
• There are more than 200 types of HPV.
• Nearly everyone is infected with HPV at some time of their life; 95% clear the infection spontaneously within 1-2 years.
• Routine Pap Screens reduced the incidence of cervical cancer in the U.S. by 74% prior to the invention of HPV vaccines.
• Cervical cancer is a slow growing cancer, with nearly 100% recovery rate with timely diagnosis and treatment.
• Gardasil 9 is the current vaccine used in the United States and most other countries in the world.
• Gardasil 9 targets only 9 strains of HPV: 7 are considered High-Risk; 2 are considered Low-Risk
• Gardasil 9 was developed because of antigenic replacement (viral shift), because Gardasil (quad) only covered 4 strains.
• There are many other HR-HPV strains that are NOT COVERED in Gardasil 9.
• HPV can be passed from mother and father to infants – it’s not just a sexually transmitted infection.
• Those infected with HPV prior to receiving Gardasil vaccine are at 44.6% increased risk of developing precancerous lesions.
• There has been no effort to test children to see if they are already HPV+, prior to administration of Gardasil vaccine.
• There is no TRUE SAFETY DATA for either Gardasil (quadrivalent) or Gardasil 9.
• Clinical trials used either Aluminum Adjuvant or another vaccine as the “placebo.”
• Gardasil 9 was approved on the basis of Gardasil being considered GRAS (generally regarded as safe).
• In the original clinical trials for Gardasil (quad), the death rate among subjects was 1 in 733.
• In the clinical trials for Gardasil 9, the rate of new autoimmune disease was 2.2%.
• Serious Adverse Events reported to VAERS for HPV vaccines are higher than SAEs reported for all other recommended
childhood (age 7-18) vaccines COMBINED, with infertility and disability among the most frequently reported outcomes.
• While other countries have responded with lawsuits and removal of recommendations after increasing reports
of serious adverse reactions to Gardasil, the United States continues to push for increased uptake of the vaccine.
• The United States government (via National Cancer Institute/NIH) is a business partner of Merck, and benefits
financially from the sale and uptake of Gardasil/Gardasil 9. Marcella Piper-Terry 10/1/2017
 WHERE’S THE GOOD NEWS???
We are not helpless. There are things we CAN DO to protect ourselves and our children.
Ways to avoid cervical cancer, according to the published medical literature
include:
• Delay coital debut.
• Minimize the number of partners, when one becomes sexually active.
• Practice consistent and correct condom use - every time.
• Don’t smoke cigarettes.
• Eat a healthy diet rich in nutrient-dense foods.
• Ensure optimal levels of folate and antioxidants, especially vitamins A,C, E,
and selenium.
• Routine Pap Smears, beginning at age 21 and continuing throughout the
lifespan, reduced the incidence of Cervical Cancer by 74% in American
women before HPV vaccines were invented.

What else can we do to guard against cervical cancer?

PROTECT THE VAGINAL MICROBIOME!!!

TInyURL.com/VagMicrobiomeHPV
TinyURL.com/VagMicrobiomeCC
TinyURL.com/VagMicrobiomeCIN
 Anything ELSE we can do?
YES!!!
And the people viewing this presentation are doing it!
• Keep learning!

• Keep reaching out and helping others to learn what you know!

• Build relationships with your legislators and educate them about the facts.

• Join your local groups and register with NVICadvocacy.org to keep up with
what’s happening in your state.