KEYWORDS

RISK MODERN FACTOR

NON COMMUNICABLE DISEASES

PASCASARJANA
UNIVERSITAS MUHAMMADIYAH ACEH

OLEH:

KELOMPOK II

CUT AINI FAUZI YANTI (1807210037)

MONICA SUSANTI ANSKAR (1807210015)
NONONG HANIS (1807210038)
RAISULI RAMADHAN (1807210026)

PROGRAM STUDI
MAGISTER KESEHATAN MASYARAKAT
BANDA ACEH
2019
1. Social determinants of common metabolic risk factors (high blood pressure, high
blood sugar, high body mass index and high waist-hip ratio) of major non-
communicable diseases in South Asia region: a systematic review protocol (Sharma
et al., 2017)

Keywords:

Key words for searching articles for the review

Key words Other variations of key words

NCDs metabolic risk factors NCDs High blood pressure,

plus proximal determinants
plus distal determinants plus
geographic location
metabolic risk hypertension, high blood
factors glucose, hyperglycemia,
diabetes, high BMI, obesity,
overweight, waist
circumference, waist-hip ratio

Proximal Determinants, risk, diet, salt

determinants intake, tobacco, smoking,
alcohol, physical inactivity,
lifestyle

Distal Social determinants, education,

determinants income, gender, race, caste,
ethnicity, socio-economic
status, wealth index, income

South Asia Nepal, India, Bangladesh,

Pakistan, Sri Lanka, Bhutan,
Maldives, Afghanistan
2. Physical activity participation and the risk of chronic diseases among South Asian
adults: protocol for a systematic review and meta-analysis.(Paudel et al., 2018)

Keywords :

Outcome measure
The primary outcome variable of interest is the occurrence of chronic disease. For this
review, the following chronic diseases will be considered: type 2 diabetes mellitus (T2DM),
breast cancer, colorectal cancer, cardiovascular disease (CHD, stroke, vascular diseases) and
musculoskeletal diseases (osteoarthritis, osteoporosis, back and neck pain). Chronic disease
markers (body weight, body mass index, blood sugar, blood pressure, lipids, cholesterol, bone
mass density and the metabolic syndrome) are the secondary outcomes of interest.

3. Methodological quality and transparency of clinical practice guidelines for the

pharmacological treatment of non-communicable diseases using the AGREE II
instrument: a systematic review protocol(Molino et al., 2017)
Keywords :

CPGs for the treatment of the following NCDs will be selected: asthma, atrial fibrillation,
benign prostatic hyperplasia, chronic obstructive pulmonary disease, congestive heart failure,
coronary artery disease and/or stable angina, dementia, depression, type 2 diabetes mellitus,
gastroesophageal reflux disease, hypercholesterolemia, hypertension, osteoarthritis and
osteoporosis. A study will be considered a CPG when it comprises recommendations of
pharmacological treatment for the treatment of the NCDs listed.

4. Physical activity for the prevention and treatment of major chronic disease: an
overview of systematic reviews(Nunan et al., 2013)
Keywords :
Cochrane Library search strategy
Id Criteria

#1 MeSH descriptor: [Exercise] explode all trees

#2 MeSH descriptor: [Exercise Therapy] explode all trees

#3 MeSH descriptor: [Motor Activity] explode all trees

#4 MeSH descriptor: [Sports] explode all trees

#5 MeSH descriptor: [Recreation] explode all trees

#6 MeSH descriptor: [Dancing] explode all trees

#7 “exercise”:ti,ab,kw
Id Criteria

#8 “physical activity” or “motor activity”:ti,ab,kw

#9 ((physical or resistance or strength) near training):ti,ab,kw

#10 training:ti

#11 sport*:ti,ab,kw

#12 walk or walking or bicycle* or cycling or run or jog or running or

jogging:ti,ab,kw

#13 athlet* or basketball or cricket or dance or dancing or football* or hockey or

netball or rugby or ski or skiing or soccer or swim* or volleyball:ti,ab,kw

#14 “physical education” or “physical training” or “physical fitness”:ti,ab,kw

#15 #1 or #2 or #3 or #4 or #5 or #6 or #7 or #8 or #9 or #10 or #11 or #12 or #13

or #14

#16 MeSH descriptor: [Cardiovascular Diseases] explode all trees

#17 MeSH descriptor: [Heart Diseases] explode all trees

#18 MeSH descriptor: [Vascular Diseases] explode all trees

#19 MeSH descriptor: [Diabetes Mellitus] explode all trees

#20 MeSH descriptor: [Renal Insufficiency, Chronic] explode all trees

#21 MeSH descriptor: [Neoplasms by Site] explode all trees

#22 MeSH descriptor: [Neoplasms] explode all trees

#23 MeSH descriptor: [Lung Diseases, Obstructive] explode all trees

#24 MeSH descriptor: [Arthritis, Rheumatoid] explode all trees

#25 MeSH descriptor: [Osteoporosis] explode all trees

#26 cardiovascular or cardio-vascular or cvd:ti

#27 ((cardiovascular or cardio-vascular) near disease*):ti,ab,kw

#28 ((cardiovascular or cardio-vascular) near (event* or outcome* or

risk*)):ti,ab,kw (Word variations have been searched)

#29 coronary or heart or chd or myocardial:ti (Word variations have been searched)

#30 ((coronary or heart) near disease*):ti,ab,kw

Id Criteria

#31 ((coronary or heart) near (event* or outcome* or risk*)):ti,ab,kw

#32 (ischaemic or ischemic or ischaemia or ischemia):ti (Word variations have been

searched)

#33 ((ischaemic or ischemic or ischaemia or ischemia) near disease*):ti,ab,kw

#34 ((ischaemic or ischemic or ischaemia or ischemia) near (event* or outcome* or

risk*)):ti,ab,kw

#35 myocardial infarct*:ti,ab,kw

#36 vascular:ti (Word variations have been searched)

#37 vascular near disease*:ti,ab,kw

#38 (vascular near (event* or outcome* or risk*)):ti,ab,kw

#39 stroke:ti,ab,kw

#40 atherosclero* or arteriosclero*:ti,ab,kw

#41 “peripheral artery” or “peripheral arterial”:ti,ab,kw

#42 “heart failure”:ti,ab,kw

#43 thrombo* or embolism or embolus or PE or DVT:ti,ab,kw

#44 hypertens* or anti-hypertens* or antihypertens*:ti,ab,kw

#45 diabet*:ti,ab,kw

#46 rheumat* or arthritis:ti,ab,kw

#47 osteoporosis:ti,ab,kw

#48 MeSH descriptor: [Overweight] explode all trees

#49 obes* or overweight:ti,ab,kw

#50 neoplas* or cancer* or carcinoma* or tumor* or tumour*:ti,ab,kw

#51 ((kidney or renal) near (disease* or failure or insufficiency)):ti,ab,kw

#52 MeSH descriptor: [Hypertension] explode all trees

#53 MeSH descriptor: [Blood Pressure] explode all trees

#54 MeSH descriptor: [Mental Disorders] this term only

 Id Criteria

#55 MeSH descriptor: [Depressive Disorder] explode all trees

#56 MeSH descriptor: [Depression] explode all trees

#57 depress*:ti,ab,kw (Word variations have been searched)

#58 ((mental* or mood) near/3 (ill* or disorder* or health)):ti (Word variations have
been searched)

#59 MeSH descriptor: [Dementia] explode all trees

#60 dementia* or alzheimer*:ti,ab,kw (Word variations have been searched)

#61 #16 or #17 or #18 or #19 or #20 or #21 or #22 or #23 or #24 or #25 or #26 or
#27 or #28 or #29 or #30 or #31 or #32 or #33 or #34 or #35 or #36 or #37 or
#38 or #39 or #40 or #41 or #42 or #43 or #44 or #45 or #46 or #47 or #48 or
#49 or #50 or #51 or #52 or #53 or #54 or #55 or #56 or #57 or #58 or #59 or
#60

#62 #15 and #61

#63 MeSH descriptor: [Heart Diseases] explode all trees and with qualifiers:
[Rehabilitation - RH]

#64 MeSH descriptor: [Vascular Diseases] explode all trees and with qualifiers:
[Rehabilitation - RH]

#65 #62 or #63 or #64

MeSH, medical subject heading.

5. Integrated models of care for diabetes and hypertension in low- and middle-income
countries (LMICs) : Protocol for a systematic review(Uwimana Nicol et al., 2018)
Keywords :
Search methods for identifying studies
We will search the following electronic databases: MEDLINE (PubMed), EMBASE
(Ovid), the Cochrane Central Register of Control Trials (CENTRAL), LILACS, Africa-
Wide Information (via EBSCO host), CINAHL, Web of Science (Core collection). For
ongoing studies, we will search the following trial registries: WHO ICTRP and
Clinicaltrials.gov. We will search conference abstracts from the International AIDS
Society Online Resource Library, the HIV/AIDS Implementers’ Meetings and the NCDs
Alliance meetings.
 Search terms will include ‘diabetes’, ‘hypertension’, ‘comorbidities , ‘integrated
healthcare delivery’, ‘low- and middle-income countries’ and their synonyms. The full
search strategy for MEDLINE (PubMed) is provided in Additional file 2. We will adapt it
for other electronic databases. We will report all search strategies in full in the final
version of the review. In addition, we will screen reference lists of included studies and
reference lists of relevant systematic reviews, and contact experts in the field and relevant
organisations (e.g. NCD Alliance) for unpublished studies. All languages will be included.

6. Modifiable and emerging risk factors for type 2 diabetes in Africa: a systematic
review and meta-analysis protocol (Issaka et al., 2018)
Keywords :
Search terms and strategy
AND
Diabet* OR T2DM*
“Risk factor*” OR “Physical activ*” OR “Physical inactivit*” OR Smok* Or Nicotin*
OR Snuff* OR diet* OR psychosocial* OR depress* OR Stress* OR Anxiet* OR
Tobacco* OR Cigarett* OR alcohol* OR Fruit* OR Vegetable* OR “Body Mass
Index*” OR BMI* OR Overweight* OR Obes* OR Urban* OR rural*
AND
Algeria* OR Angola* OR Benin* OR Botswana* OR “Burkina Faso*” OR Burundi*
OR “Cape Verde*” OR Cameroon* OR Chad* OR Comoros* OR Congo* OR
Djibouti* OR Egypt* OR “Equatorial Guinea*” OR Eritrea* OR Ethiopia* OR Gabon*
OR Gambia* OR Ghana* OR “Guinea-Bissau*” OR “Ivory Coast*” OR Kenya* OR
Lesotho* OR Liberia* OR Libya* OR Madagascar* OR Malawi* OR Mali* OR
Mauritania* OR Mauritius* OR Morocco* OR Mozambique* OR Namibia* OR
Niger* OR Rwanda* OR “Sao Tome and Principe*” OR Senegal* OR Seychelles* OR
“Sierra Leone*” OR Somalia* OR “South* Africa*” OR Sudan* OR Swaziland* OR
Tanzania* OR Togo* OR Tunisia* OR Uganda* OR Zambia* OR Zimbabwe* OR
“Central Africa*” OR “West* Africa*” OR “East* Africa*” OR “North* Africa*” OR
“sub Saharan Africa*” OR Afric*

7. Prevalence of metabolic syndrome among HIV-positive and HIV-negative

populations in sub-Saharan Africa—a systematic review and meta-analysis
(Todowede et al., 2019)
Keywords :
Outcome of interest
The primary outcome of this study was to compare the pooled prevalence of metabolic
syndrome among people living with HIV and uninfected populations in SSA. The
secondary aim was to compare metabolic syndrome subcomponents (namely visceral
obesity, hypertension, diabetes, triglycerides, HDL cholesterol) among people living
with HIV and uninfected populations in SSA.

MEDLINE (PubMed), EBSCOhost, and Cochrane Database of Systematic Reviews and

Web of sciences databases were searched for papers published between January 1990
and December 2017. The search terms used a combination of relevant medical subject
 headings (MeSH) and database specific terms with an African search filter. The search
strategy and the number of returned items are presented in Appendix 1 and 2. The
reference lists of identified articles were traced through a web of science, and conference
proceedings checked using the International AIDS society abstract archives. The titles of
retrieved articles were examined to exclude ineligible articles. Given a large number of
Francophile countries in SSA, this review included eligible studies published in French
and were reviewed by a French-speaking reviewer (SM). The selection of studies was a
multistep process with two reviewers (OO, SM) independently screening the abstract and
full text for potential eligibility using the inclusion criteria, and discrepancies were
resolved through arbitration with a third reviewer (BS). The flow diagram of the study
selection and exclusion process is presented in Fig. 1. The interrater agreement for
abstract and full-text screening was high at 90% and 100% respectively.

8. Impact of different dietary approaches on glycemic control and cardiovascular risk

factors in patients with type 2 diabetes: a protocol for a systematic review and
network meta-analysis(Schwingshackl et al., 2017)
Keywords :
Search strategy
The search will be performed by LS and CS, and differences will be resolved by
discussion with a third reviewer (HB). We will conduct searches in PubMed, Cochrane
CENTRAL, and Google Scholar. We will search for articles of original research using the
following search terms for PubMed:
#1
diet OR diet[MeSH Terms]

#2
diabetes OR diabetes[MeSH Terms]

#3
(low-carbohydrate[All Fields] OR high-carbohydrate[All Fields] OR low-fat[All Fields]
OR high-fat[All Fields] OR low-protein[All Fields] OR high-protein[All Fields] OR
vegetarian[All Fields] OR vegan[All Fields] OR Mediterranean[All Fields] OR
DASH[All Fields] OR dietary approaches to stop hypertension[All Fields] OR glycaemic
index[All Fields] OR glycaemic load[All Fields] OR Paleolithic[All Fields] OR low-
calorie[All Fields] OR atkins[All Fields])

#4
(glucose[MeSH Terms] OR glycemic[All Fields] OR glycaemia[All Fields] OR
glycaemic[All Fields] OR glycemia[All Fields] OR HbA1c[All Fields] OR A1c [All
Fields] OR glycated[All Fields] OR glycosylated[All Fields] OR lipids[MeSH Terms] OR
 body weight[MeSH Terms] OR cholesterol*[All Fields] OR lipid*[All Fields] OR
lipoprotein*[All Fields] OR “high density”[All Fields] OR “low density” [All Fields] OR
triacylglycerol*[All Fields] OR LDL[All Fields] OR HDL[All Fields])

#5
(randomized controlled trial[All Fields] OR randomized[All Fields] OR clinical trials as
topic[All Fields] OR placebo[All Fields] OR randomly[All Fields] OR trial[All Fields]
NOT animals[All Fields])

#6
(#1 AND #2 AND #3 AND #4 AND #5)

The search strategy will be adapted for each database.

Moreover, the reference lists from the retrieved original articles; systematic reviews and
meta-analyses will be checked to search for further relevant studies. We will also conduct
searches in Clinicaltrials.gov (http://clinicaltrials.gov/) and the World Health
Organization International Clinical Trials Registry Platform to look for ongoing trials and
opengrey (http://www.opengrey.eu/).
There will be no restrictions by language or publication year. Studies published in
languages other than English will be translated by international scientists in our institute.

9. T cell activation and cardiovascular risk in type 2 diabetes mellitus: a protocol for a
systematic review and meta-analysis (Nyambuya et al., 2018)
Keywords :
Search strategy
The systematic search will be conducted without any language restrictions. However, for
none English articles, only those google translatable will be searched. The search strategy
will consist of the following major keywords and their respective synonyms: type 2 diabetes
mellitus, hyperglycaemia, inflammation, CVDs, T cell activation and exhaustion. For each
keyword, multiple synonyms will be searched in the title or abstract. In addition, the
reference lists of selected studies will be scanned to identify relevant literature. A search
strategy will be developed using medical subject headings (MeSH) words and their respective
synonyms on MEDLINE (see Additional file 2). The search strategy will also be adapted to
grey literature, Embase and Cochrane Central Register of Controlled Trials electronic
databases and will be peer-reviewed by a librarian specialist.
10. Food groups and risk of chronic disease: a protocol for a systematic review and
network meta-analysis of cohort studies (Schwingshackl et al., 2016)
Keywords :
Search strategy
The search strategy was developed by LS, SS and HB, and will be performed by LS, AB,
MSM and KI, and differences resolved by discussion with a third reviewer (HB). We will
conduct searches in PubMed (from 1966) and EMBASE (from 1980). We will search for
articles of original research by using the following search terms:
#1
food and beverages [MeSH Terms]
#2
food*[tiab] OR whole grain*[tiab] OR refined grain*[tiab] OR cereal*[tiab] OR
pasta*[tiab] OR rice*[tiab] OR potato*[tiab] OR vegetable*[tiab] OR fruit*[tiab] OR
nut*[tiab] OR legume*[tiab] OR bean*[tiab] OR egg*[tiab] OR dairy[tiab] OR
dairies[tiab] OR milk[tiab] OR yogurt[tiab] OR cheese[tiab] OR fish[tiab] OR
seafood[tiab] OR meat[tiab] OR processed meat[tiab] OR sugar sweetened
beverage*[tiab]
#3
mortality OR incidence OR cardiovascular OR coronary OR stroke OR cancer OR
neoplasm OR neoplastic disease OR diabetes OR vascular OR myocardial infarction
#4
prospective OR follow-up OR cohort OR longitudinal

#5
(#1 OR #2) AND #3 AND #4

Moreover, the reference lists from the retrieved articles; systematic reviews and meta-
analyses will be checked to search for further relevant studies (umbrella review of
systematic review and meta-analyses). There will be no restrictions on language or
publication year. Studies published in languages other than English will be translated by
international scientists in our institute.
DAFTAR PUSTAKA
Issaka A., Paradies Y. & Stevenson C., Modifiable and emerging risk factors for type 2
diabetes in Africa: a systematic review and meta-analysis protocol, Systematic Reviews,
2018;7(1):139.

Molino C.d.G.R.C., Ribeiro E., Romano-Lieber N.S., Stein A.T. & Melo D.O.d., Methodological
quality and transparency of clinical practice guidelines for the pharmacological treatment
of non-communicable diseases using the AGREE II instrument: a systematic review
protocol, Systematic Reviews, 2017;6(1):220.

Nunan D., Mahtani K.R., Roberts N. & Heneghan C., Physical activity for the prevention and
treatment of major chronic disease: an overview of systematic reviews, Systematic
Reviews, 2013;2(1):56.

Nyambuya T.M., Dludla P.V. & Nkambule B.B., T cell activation and cardiovascular risk in
type 2 diabetes mellitus: a protocol for a systematic review and meta-analysis, Systematic
Reviews, 2018;7(1):167.

Paudel S., Owen A.J., Owusu-Addo E. & Smith B.J., Physical activity participation and the
risk of chronic diseases among South Asian adults: protocol for a systematic review and
meta-analysis, Systematic Reviews, 2018;7(1):177.

Schwingshackl L., Chaimani A., Bechthold A., Iqbal K., Stelmach-Mardas M., Hoffmann G., et
al., Food groups and risk of chronic disease: a protocol for a systematic review and
network meta-analysis of cohort studies, Systematic Reviews, 2016;5(1):125.

Schwingshackl L., Chaimani A., Hoffmann G., Schwedhelm C. & Boeing H., Impact of
different dietary approaches on glycemic control and cardiovascular risk factors in patients
with type 2 diabetes: a protocol for a systematic review and network meta-analysis,
Systematic Reviews, 2017;6(1):57.

Sharma S.R., Mishra S.R., Wagle K., Page R., Matheson A., Lambrick D., et al., Social
determinants of common metabolic risk factors (high blood pressure, high blood sugar,
high body mass index and high waist-hip ratio) of major non-communicable diseases in
South Asia region: a systematic review protocol, Systematic Reviews, 2017;6(1):183.

Todowede O.O., Mianda S.Z. & Sartorius B., Prevalence of metabolic syndrome among HIV-
positive and HIV-negative populations in sub-Saharan Africa—a systematic review and
meta-analysis, Systematic Reviews, 2019;8(1):4.

Uwimana Nicol J., Rohwer A., Young T., Bavuma C.M. & Meerpohl J.J., Integrated models of
care for diabetes and hypertension in low- and middle-income countries (LMICs) : Protocol
for a systematic review, Systematic Reviews, 2018;7(1):203.