WATER DISTRIBUTION
Osmosis is the process that constitutes the movement of solvent across a membrane in response to
differences in osmotic pressure across the two sides of the membrane.
Sodium
Glucose
Urea
THE CATIONS
SODIUM Reabsorption : Actively on Ascending loop of Henle (with chloride as limiting
factor) and Distal Tubule (in exchange for K)
POTASSIUM
CALCIUM
Filtration : 80% of Serum Mg2+
MAGNESIUM Reabsorption : 95% of Filtered Mg2+
Excretion : 5% of Filtered Mg2+
PATHOPHYSIOLOGY
Electrolytes/wynlor| 1
UNIVERSITY OF SANTO TOMAS
FACULTY OF PHARMACY | DEPARTMENT OF MEDICAL TECHNOLOGY
RENAL FAILURE
Potassium Sodium
Magnesium
Calcium
ALKALOSIS
[in metabolic alkalosis;
electroneutality : high bicarbonate
Chloride in blood, the negative charge must
be balanced by excreting chloride
ions]
[Intracellular shift : Hydrogen ions
move out of the cell to balance the
Potassium pH; potassium moves inside the
cell for every release of cellular
Hydrogen]
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